Page last updated: 2024-09-03

pd 117302 and Ache

pd 117302 has been researched along with Ache in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's5 (62.50)18.2507
2000's0 (0.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abraham, S; Hayes, ES; Pugsley, MK; Saint, DA; Walker, MJ1
Carruette, A; Garret, C; Moussaoui, S1
Diop, L; Junien, JL; Langlois, A; Pascaud, X; Rivière, PJ1
Angel, F; Chevalier, E; Dahl, SG; Friese, N; Junien, JL; Pascaud, X; Riviere, PJ1
Cowan, A; Wheeler-Aceto, H2
Cowan, A; Ianone, M; Porreca, F; Wheeler, H1
Hill, RG; Hughes, J; Johnson, MA; Leighton, GE; Meecham, KG1

Other Studies

8 other study(ies) available for pd 117302 and Ache

ArticleYear
An examination of the cardiac actions of PD117,302, a κ-opioid receptor agonist.
    European journal of pharmacology, 2015, Aug-15, Volume: 761

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Binding, Competitive; Cardiac Pacing, Artificial; Cerebellum; Coronary Occlusion; Disease Models, Animal; Dose-Response Relationship, Drug; Electrocardiography; Guinea Pigs; Heart Conduction System; Heart Rate; Heart Ventricles; Isolated Heart Preparation; Ligands; Male; Mice, Inbred BALB C; Myocardial Contraction; Pain; Pain Threshold; Potassium Channel Blockers; Potassium Channels; Protein Binding; Pyrroles; Radioligand Assay; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Sodium Channel Blockers; Sodium Channels; Thiophenes; Ventricular Function, Left; Ventricular Pressure

2015
Further evidence that substance P is a mediator of both neurogenic inflammation and pain: two phenomena inhibited either by postsynaptic blockade of NK1 receptors or by presynaptic action of opioid receptor agonists.
    Regulatory peptides, 1993, Jul-02, Volume: 46, Issue:1-2

    Topics: Analgesics; Animals; Anticonvulsants; Electric Stimulation; Formaldehyde; Indoles; Inflammation; Isoindoles; Male; Mice; Mice, Inbred Strains; Morphine; Pain; Peripheral Nerves; Pyrroles; Rats; Rats, Sprague-Dawley; Substance P; Thiophenes

1993
Effect of fedotozine on the cardiovascular pain reflex induced by distension of the irritated colon in the anesthetized rat.
    European journal of pharmacology, 1994, Dec-27, Volume: 271, Issue:2-3

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Acetates; Acetic Acid; Amino Acid Sequence; Anesthesia; Animals; Benzyl Compounds; Blood Pressure; Colon; Dose-Response Relationship, Drug; Male; Molecular Sequence Data; Pain; Propylamines; Pyrroles; Pyrrolidines; Rats; Rats, Sprague-Dawley; Reflex; Thiophenes

1994
Reversal by kappa-agonists of peritoneal irritation-induced ileus and visceral pain in rats.
    Life sciences, 1997, Volume: 60, Issue:9

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Acetic Acid; Analgesics; Animals; Benzofurans; Benzomorphans; Cyclazocine; Fentanyl; Gastric Emptying; Intestinal Pseudo-Obstruction; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Peritoneum; Pyrroles; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Opioid, mu; Thiophenes

1997
Involvement of a peripheral component in the antinociceptive effects of opioids in a model of tonic pain.
    NIDA research monograph, 1990, Volume: 105

    Topics: Animals; Anticonvulsants; Disease Models, Animal; Male; Morphine; Narcotics; Pain; Peripheral Nerves; Pyrroles; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Thiophenes

1990
Standardization of the rat paw formalin test for the evaluation of analgesics.
    Psychopharmacology, 1991, Volume: 104, Issue:1

    Topics: Analgesics; Animals; Aspirin; Behavior, Animal; Decerebrate State; Foot; Formaldehyde; Male; Morphine; Pain; Pyrroles; Rats; Rats, Inbred Strains; Reference Standards; Thiophenes

1991
Comparison of PD 117302, a kappa agonist, and morphine on colonic transit and formalin-induced pain in rats.
    Proceedings of the Western Pharmacology Society, 1989, Volume: 32

    Topics: Animals; Colon; Dose-Response Relationship, Drug; Formaldehyde; Gastrointestinal Transit; Male; Morphine; Pain; Pyrroles; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Thiophenes

1989
Pharmacological profile of PD 117302, a selective kappa-opioid agonist.
    British journal of pharmacology, 1987, Volume: 92, Issue:4

    Topics: Analgesics; Animals; Depression, Chemical; Diuretics; Gastrointestinal Motility; Injections, Intravenous; Male; Mice; Pain; Pyrroles; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Opioid; Receptors, Opioid, kappa; Respiration; Substance-Related Disorders; Thiophenes

1987