pca 4248 has been researched along with Inflammation in 3 studies
PCA 4248: structure given in first source; platelet activating factor antagonist
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Zymosan-induced articular hyperalgesia, oedema and neutrophil migration were dose-dependently reduced following pretreatment with selective PAFR antagonists, UK74505 (5, 10 and 20 mg/kg) and PCA4248 (3, 10, 30 mg/kg)." | 1.39 | The role of PAF/PAFR signaling in zymosan-induced articular inflammatory hyperalgesia. ( Cunha, FQ; Cunha, TM; Ferreira, SH; Guerrero, AT; Pinto, LG; Verri, WA; Vieira, SM; Zaperlon, AC; Zarpelon, AC, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Guerrero, AT | 1 |
| Zarpelon, AC | 1 |
| Zaperlon, AC | 1 |
| Vieira, SM | 1 |
| Pinto, LG | 1 |
| Ferreira, SH | 1 |
| Cunha, FQ | 1 |
| Verri, WA | 1 |
| Cunha, TM | 1 |
| Matsumura, Y | 1 |
| Byrne, SN | 1 |
| Nghiem, DX | 1 |
| Miyahara, Y | 1 |
| Ullrich, SE | 1 |
| Melnikova, V | 1 |
| Bar-Eli, M | 1 |
1 review available for pca 4248 and Inflammation
| Article | Year |
|---|---|
Inflammation and melanoma growth and metastasis: the role of platelet-activating factor (PAF) and its receptor.
Topics: Animals; Cyclic AMP Response Element-Binding Protein; Dihydropyridines; Humans; Inflammation; Lung N | 2007 |
2 other studies available for pca 4248 and Inflammation
| Article | Year |
|---|---|
The role of PAF/PAFR signaling in zymosan-induced articular inflammatory hyperalgesia.
Topics: Animals; Dihydropyridines; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperalgesia; I | 2013 |
A role for inflammatory mediators in the induction of immunoregulatory B cells.
Topics: Adoptive Transfer; Animals; Antigens, CD19; B-Lymphocytes; Dermatitis, Contact; Dihydropyridines; Fl | 2006 |