Page last updated: 2024-08-26

paxilline and Neoplasms

paxilline has been researched along with Neoplasms in 34 studies

Research

Studies (34)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (5.88)	18.2507
2000's	11 (32.35)	29.6817
2010's	14 (41.18)	24.3611
2020's	7 (20.59)	2.80

Authors

Authors	Studies
Kmoníčková, E; Peterková, L; Rimpelová, S; Ruml, T	1
Chen, H; He, P; Lin, G; Lin, Z; Liu, C; Liu, G; Lu, Z; Mu, D; Shi, Y; Zhang, Y; Zheng, H	1
Chen, W; Huang, X; Liu, W; Liu, X; Luo, W	1
Abu-Thuraia, A; Apcher, C; Bagci, H; Boulais, J; Chidiac, R; Côté, JF; Daly, RJ; Davidson, D; Delliaux, C; Ferron, M; Gingras, AC; Goyette, MA; Gratton, JP; Schott, C; Thibault, MP; Veillette, A	1
Alpha, KM; Turner, CE; Xu, W	1
Antoniades, I; Charalambous, A; Christodoulou, A; Christoforou, M; Kalalidou, K; Kyriakou, M; Skourides, PA	1
Chen, Y; Feng, Y; Gao, Z; Guo, Y; Liu, Q; Shen, P; Tan, L; Xiao, Y; Zhang, S; Zhao, H; Zhao, J; Zhao, Y	1
Deakin, NO; Dubois, F; Goreczny, GJ; Gulvady, AC; Turner, CE	1
Ferrari, A; Giampietro, C; Lendenmann, T; Panagiotakopoulou, M; Poulikakos, D; Pramotton, FM; Stefopoulos, G	1
Baker, M; Birdsey, GM; Hart, IR; Hodivala-Dilke, K; Jones, DT; Kostourou, V; Lechertier, T; Lees, DM; Parsons, M; Ramjaun, AR; Randi, AM; Reynolds, LE; Robinson, SD; Tavora, B	1
Gao, M; Liu, X; Ren, H; Shen, Y; Sun, H; Wang, L	1
Hammes, SR; Miedlich, SU; Sen, A	1
Bendell, JC; Dellinger, A; Howard, L; Hurwitz, HI; Jia, J; Lee, PH; Nixon, AB; Pang, H; Ready, NA; Starr, MD; Uronis, HE	1
Cemeli, T; Colomina, N; Dolcet, X; Fernández-Hernández, R; Ferrezuelo, F; Fusté, NP; Garí, E; Mirantes, C; Pedraza, N; Rafel, M; Torres-Rosell, J	1
Chen, H; Collier, C; Drake, LE; Macleod, KF; Mowers, EE; Mui, S; Sharifi, MN; Zamora, M	1
Macleod, KF; Mowers, EE; Sharifi, MN	1
Akasaka, T; Iwabuchi, S; Kishi, T; Mayanagi, T; Sobue, K	1
Haura, EB; Kim, LC; Song, L	1
Lu, Z; Zheng, Y	1
Ozawa, T; Sato, H; Takino, T; Tsuge, H	1
Adachi, E; Fujisaki, H; Hattori, S; Irie, S; Sasaki, J	1
Furukawa, K; Hamamura, K; Nakashima, H; Ohkawa, Y; Zhang, Q	1
Bennin, DA; Boateng, LR; Cortesio, CL; Huttenlocher, A; Piazza, TM	1
Avraamides, CJ; Foubert, P; Kang, SW; Kerbel, RS; Schmid, MC; Shaked, Y; Varner, JA	1
Enns, A; Haier, J; Korb, T; Nicolson, GL; Schlüter, K; Senninger, N; Spiegel, HU	1
Enns, A; Fisch, KM; Gassmann, P; Haier, J; Nicolson, GL; von Sengbusch, A	1
Chiariotti, L; Florio, T; Fusco, A; Iuliano, R; Pera, IL; Santoro, M; Schettini, G; Susini, C; Trapasso, F; Viglietto, G	1
Asahara, T; Hino, S; Kikuchi, A; Kobayashi, T; Oue, N; Yasui, W; Zollo, M	1
Hashimoto, S; Mazaki, Y; Onodera, Y; Sabe, H	1
Bar-Shavit, R; Lotem, M; Maoz, M; Pokroy, E; Salah, Z; Uziely, B	1
Ahn, K; Choi, S; Lee, HK; Lee, JW; Lee, SA; Lee, SY; Oh, SR	1
Chambers, AF; Denhardt, DT	1
Hashimoto, S; Mazaki, Y; Sabe, H	1
Morrison, PT; Pisick, E; Salgia, R; Sattler, M	1

Reviews

7 review(s) available for paxilline and Neoplasms

Article	Year
Sarco/Endoplasmic Reticulum Calcium ATPase Inhibitors: Beyond Anticancer Perspective. Journal of medicinal chemistry, 2020, 03-12, Volume: 63, Issue:5 Topics: Animals; Antineoplastic Agents; Enzyme Inhibitors; Gene Regulatory Networks; Humans; Neoplasms; Protein Structure, Secondary; Sarcoplasmic Reticulum Calcium-Transporting ATPases	2020
The Role of Paxillin Aberrant Expression in Cancer and Its Potential as a Target for Cancer Therapy. International journal of molecular sciences, 2023, May-04, Volume: 24, Issue:9 Topics: Antineoplastic Agents; Carcinogenesis; Cell Line, Tumor; Cell Movement; Humans; Neoplasms; Paxillin	2023
Src kinases as therapeutic targets for cancer. Nature reviews. Clinical oncology, 2009, Volume: 6, Issue:10 Topics: Actins; Animals; Cell Adhesion; Cell Movement; Cell Proliferation; Cell Survival; Clinical Trials as Topic; Crk-Associated Substrate Protein; Drug Evaluation, Preclinical; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation, Neoplastic; Genes, ras; GTPase-Activating Proteins; Humans; Integrins; MAP Kinase Signaling System; Neoplasm Metastasis; Neoplasms; Paxillin; Protein Structure, Tertiary; Receptor Protein-Tyrosine Kinases; Signal Transduction; src-Family Kinases; Time Factors; Transcription Factors	2009
[Molecular complex in the vicinity of cell membrane generating cancer phenotypes]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 2008, Volume: 53, Issue:12 Suppl Topics: Animals; Antigens, Neoplasm; Cell Adhesion; Cell Division; Cell Survival; Crk-Associated Substrate Protein; Epitopes; Focal Adhesion Protein-Tyrosine Kinases; Gangliosides; Integrins; Neoplasm Invasiveness; Neoplasms; Paxillin; Signal Transduction	2008
ArfGAP family proteins in cell adhesion, migration and tumor invasion. Current opinion in cell biology, 2006, Volume: 18, Issue:5 Topics: Adaptor Proteins, Signal Transducing; ADP-Ribosylation Factors; Animals; Cell Adhesion; Cell Cycle Proteins; Cell Movement; GTPase-Activating Proteins; Humans; Neoplasm Invasiveness; Neoplasms; Paxillin; Superoxides	2006
Overcoming obstacles to metastasis--defenses against host defenses: osteopontin (OPN) as a shield against attack by cytotoxic host cells. Journal of cellular biochemistry, 1994, Volume: 56, Issue:1 Topics: Amino Acid Oxidoreductases; Animals; Cell Adhesion; Cell Adhesion Molecules; Cytoskeletal Proteins; Endothelium, Vascular; Gene Expression; Humans; Integrins; Macrophages; Models, Biological; Neoplasm Metastasis; Neoplasms; Nitric Oxide Synthase; Osteopontin; Paxillin; Phosphoproteins; Phosphorylation; Receptors, Cytoadhesin; Receptors, Vitronectin; Sialoglycoproteins; Signal Transduction	1994
Role of the cytoskeletal protein paxillin in oncogenesis. Critical reviews in oncogenesis, 2000, Volume: 11, Issue:1 Topics: Amino Acid Motifs; Animals; Cell Adhesion Molecules; Cell Transformation, Neoplastic; Cytokines; Cytoskeletal Proteins; Humans; Integrins; Neoplasms; Paxillin; Phosphoproteins; Phosphorylation; Receptors, Growth Factor; Signal Transduction	2000

Trials

1 trial(s) available for paxilline and Neoplasms

Article	Year
A Phase I/biomarker study of bevacizumab in combination with CNTO 95 in patients with advanced solid tumors. Cancer chemotherapy and pharmacology, 2015, Volume: 75, Issue:2 Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Biomarkers, Tumor; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Neoplasms; Neovascularization, Pathologic; Paxillin	2015

Article

Year

A Phase I/biomarker study of bevacizumab in combination with CNTO 95 in patients with advanced solid tumors.

Cancer chemotherapy and pharmacology, 2015, Volume: 75, Issue:2

Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Biomarkers, Tumor; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Neoplasms; Neovascularization, Pathologic; Paxillin

2015

Other Studies

26 other study(ies) available for paxilline and Neoplasms

Article	Year
Biomimetic nanoparticles blocking autophagy for enhanced chemotherapy and metastasis inhibition via reversing focal adhesion disassembly. Journal of nanobiotechnology, 2021, Dec-24, Volume: 19, Issue:1 Topics: Animals; Antineoplastic Agents; Autophagy; Biomimetic Materials; Cadherins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Carriers; Drug Liberation; Focal Adhesions; Humans; Hydroxychloroquine; Lung Neoplasms; Mice; Nanoparticles; Neoplasms; Oxaliplatin; Paxillin; Polylactic Acid-Polyglycolic Acid Copolymer	2021
AXL confers cell migration and invasion by hijacking a PEAK1-regulated focal adhesion protein network. Nature communications, 2020, 07-17, Volume: 11, Issue:1 Topics: Adaptor Proteins, Signal Transducing; Axl Receptor Tyrosine Kinase; Cell Line, Tumor; Cell Movement; Focal Adhesions; Humans; Neoplasm Invasiveness; Neoplasms; Paxillin; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Signal Transduction	2020
Paxillin family of focal adhesion adaptor proteins and regulation of cancer cell invasion. International review of cell and molecular biology, 2020, Volume: 355 Topics: Focal Adhesions; Humans; Intracellular Signaling Peptides and Proteins; LIM Domain Proteins; Neoplasm Invasiveness; Neoplasms; Paxillin; Signal Transduction	2020
FAK displacement from focal adhesions: a promising strategy to target processes implicated in cancer progression and metastasis. Cell communication and signaling : CCS, 2021, 01-07, Volume: 19, Issue:1 Topics: Cell Line; Cell Movement; Disease Progression; Focal Adhesion Protein-Tyrosine Kinases; Focal Adhesions; Humans; Neoplasms; Paxillin; Protein Domains	2021
Pan-cancer analysis reveals an immunological role and prognostic potential of PXN in human cancer. Aging, 2021, 06-16, Volume: 13, Issue:12 Topics: Cancer-Associated Fibroblasts; Gene Expression Regulation, Neoplastic; Humans; Kaplan-Meier Estimate; Lymphocytes, Tumor-Infiltrating; Mutation; Neoplasms; Paxillin; Phosphorylation; Prognosis; Survival Analysis	2021
Hic-5 expression is a major indicator of cancer cell morphology, migration, and plasticity in three-dimensional matrices. Molecular biology of the cell, 2018, 07-15, Volume: 29, Issue:13 Topics: Amino Acid Motifs; Cell Line, Tumor; Cell Movement; Cell Plasticity; Cell Shape; Extracellular Matrix; Humans; Intracellular Signaling Peptides and Proteins; LIM Domain Proteins; Mesoderm; Neoplasm Invasiveness; Neoplasms; Paxillin; Phenotype; Phosphorylation; Protein Binding; Protein Domains; Vinculin	2018
Cell cycle-dependent force transmission in cancer cells. Molecular biology of the cell, 2018, 10-15, Volume: 29, Issue:21 Topics: Biomechanical Phenomena; Cell Cycle; Cell Movement; Cell Proliferation; Drug Resistance, Neoplasm; Focal Adhesion Protein-Tyrosine Kinases; HEK293 Cells; HeLa Cells; Humans; MCF-7 Cells; Neoplasm Invasiveness; Neoplasms; Paxillin; Phenotype; Phosphorylation; Tamoxifen	2018
FAK-heterozygous mice display enhanced tumour angiogenesis. Nature communications, 2013, Volume: 4 Topics: Animals; Cell Proliferation; Cell Separation; Cell Survival; Endothelial Cells; Focal Adhesion Kinase 1; Heterozygote; Immunohistochemistry; In Vitro Techniques; Mice; Mutant Proteins; Neoplasms; Neovascularization, Pathologic; Paxillin; Proto-Oncogene Proteins c-akt; Signal Transduction; Subcutaneous Tissue; Talin; Tumor Burden; Vinculin	2013
[Study on FAK regulation of migration of vascular endothelial cells depending upon focal adhesion proteins]. Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi, 2013, Volume: 30, Issue:3 Topics: Cell Adhesion; Cell Movement; Cells, Cultured; Endothelial Cells; Focal Adhesion Protein-Tyrosine Kinases; Focal Adhesions; Humans; Neoplasms; Neovascularization, Pathologic; Paxillin; Talin; Vinculin	2013
Paxillin and steroid signaling: from frog to human. Methods in molecular biology (Clifton, N.J.), 2014, Volume: 1204 Topics: Animals; Anura; Breast Neoplasms; Female; Germ Cells; Humans; Intercellular Signaling Peptides and Proteins; Male; Meiosis; Neoplasms; Paxillin; Prostatic Neoplasms; Signal Transduction; Steroids	2014
Cytoplasmic cyclin D1 regulates cell invasion and metastasis through the phosphorylation of paxillin. Nature communications, 2016, 05-16, Volume: 7 Topics: Animals; Cell Line, Tumor; Cell Membrane; Cyclin D1; Cyclin-Dependent Kinase 4; Cytoplasm; Down-Regulation; Fibroblasts; Gene Knockdown Techniques; HEK293 Cells; Humans; Mice; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms; Paxillin; Phosphorylation; Phosphoserine; Protein Binding; rac1 GTP-Binding Protein; Rats; Substrate Specificity	2016
Autophagy Promotes Focal Adhesion Disassembly and Cell Motility of Metastatic Tumor Cells through the Direct Interaction of Paxillin with LC3. Cell reports, 2016, 05-24, Volume: 15, Issue:8 Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Autophagosomes; Autophagy; Autophagy-Related Proteins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Focal Adhesions; Gene Knockdown Techniques; Mice, Inbred BALB C; Microtubule-Associated Proteins; Neoplasm Metastasis; Neoplasms; Paxillin; Protein Binding; Protein Stability; Protein Transport; src-Family Kinases	2016
Novel insights into how autophagy regulates tumor cell motility. Autophagy, 2016, Volume: 12, Issue:9 Topics: Amino Acid Motifs; Autophagy; Cell Adhesion; Cell Movement; Cytoskeletal Proteins; Cytoskeleton; Focal Adhesions; Humans; Neoplasm Metastasis; Neoplasms; Paxillin; Phosphorylation; Signal Transduction	2016
Myocardin-related transcription factor A (MRTF-A) activity-dependent cell adhesion is correlated to focal adhesion kinase (FAK) activity. Oncotarget, 2016, Nov-01, Volume: 7, Issue:44 Topics: Actins; Animals; Cell Adhesion; Cell Line, Tumor; Cell Movement; Focal Adhesion Kinase 1; Focal Adhesions; Gene Expression Regulation, Neoplastic; Humans; Integrins; Mice; Microscopy, Fluorescence; Neoplasms; Paxillin; Phosphorylation; Rats; Real-Time Polymerase Chain Reaction; RNA Interference; RNA, Small Interfering; Serum Response Factor; Signal Transduction; src-Family Kinases; Trans-Activators; Up-Regulation	2016
Paradoxical roles of FAK in tumor cell migration and metastasis. Cell cycle (Georgetown, Tex.), 2009, Nov-01, Volume: 8, Issue:21 Topics: Animals; Cell Adhesion; Cell Movement; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation; Genes, ras; Humans; Integrins; Mice; Neoplasm Metastasis; Neoplasms; Paxillin; Phosphorylation; Receptor Protein-Tyrosine Kinases; Signal Transduction	2009
MT1-MMP promotes cell growth and ERK activation through c-Src and paxillin in three-dimensional collagen matrix. Biochemical and biophysical research communications, 2010, Jun-11, Volume: 396, Issue:4 Topics: Cell Line, Tumor; Cell Proliferation; Collagen; CSK Tyrosine-Protein Kinase; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; HeLa Cells; Humans; Matrix Metalloproteinase 14; Neoplasms; Paxillin; Protein-Tyrosine Kinases; src-Family Kinases	2010
Delay of cell cycle progression and induction death of cancer cells on type I collagen fibrils [corrected]. Connective tissue research, 2011, Volume: 52, Issue:3 Topics: Animals; Bromodeoxyuridine; Caspase 3; Caspase 9; Cattle; Cell Cycle; Cell Death; Cell Line, Tumor; Cell Proliferation; Cell Shape; Cell Survival; Collagen Type I; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Focal Adhesion Protein-Tyrosine Kinases; Focal Adhesions; Humans; Integrin alpha2beta1; Microscopy, Electron, Scanning; Neoplasms; Paxillin; Poly(ADP-ribose) Polymerases; Protein Transport; Proto-Oncogene Proteins c-akt; Time Factors	2011
Calpain-mediated proteolysis of paxillin negatively regulates focal adhesion dynamics and cell migration. The Journal of biological chemistry, 2011, Mar-25, Volume: 286, Issue:12 Topics: Amino Acid Motifs; Amino Acid Substitution; Calpain; Cell Movement; Cytoskeletal Proteins; Focal Adhesions; Glycoproteins; HEK293 Cells; HeLa Cells; Humans; Neoplasm Invasiveness; Neoplasms; Paxillin; Point Mutation; Zyxin	2011
Combined blockade of integrin-α4β1 plus cytokines SDF-1α or IL-1β potently inhibits tumor inflammation and growth. Cancer research, 2011, Nov-15, Volume: 71, Issue:22 Topics: Animals; CD11b Antigen; Cell Movement; Chemokine CXCL12; Inflammation; Integrin alpha4beta1; Interleukin-1beta; Mice; Mice, Inbred C57BL; Myeloid Cells; Neoplasms; Paxillin; Talin	2011
Integrity of actin fibers and microtubules influences metastatic tumor cell adhesion. Experimental cell research, 2004, Sep-10, Volume: 299, Issue:1 Topics: Actin Cytoskeleton; Animals; Cell Adhesion; Cytoskeletal Proteins; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Liver; Male; Microcirculation; Microtubules; Neoplasm Metastasis; Neoplasms; Paxillin; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Signal Transduction; Tubulin; Tubulin Modulators; Tumor Cells, Cultured	2004
Focal adhesion kinase regulates metastatic adhesion of carcinoma cells within liver sinusoids. The American journal of pathology, 2005, Volume: 166, Issue:2 Topics: Animals; Carcinoma; Carcinoma, Hepatocellular; Cell Adhesion; Cell Line, Tumor; Collagen; Colon; Cytoskeletal Proteins; Dose-Response Relationship, Drug; Endothelium, Vascular; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Immunoprecipitation; Liver; Liver Neoplasms; Male; Microcirculation; Microscopy, Fluorescence; Neoplasm Metastasis; Neoplasms; Oligonucleotides; Paxillin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Time Factors; Transfection; Tyrosine	2005
The rat tyrosine phosphatase eta increases cell adhesion by activating c-Src through dephosphorylation of its inhibitory phosphotyrosine residue. Oncogene, 2005, Apr-28, Volume: 24, Issue:19 Topics: Animals; Blotting, Western; Cell Adhesion; CSK Tyrosine-Protein Kinase; Cytoskeletal Proteins; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Glutathione Transferase; Humans; Immunoblotting; Immunoprecipitation; Mutation; Neoplasms; Paxillin; Peptides; Phenotype; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Binding; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Receptor-Like Protein Tyrosine Phosphatases, Class 3; src-Family Kinases; Thyroid Gland; Thyroid Neoplasms; Transfection; Tyrosine	2005
Glycogen synthase kinase 3 and h-prune regulate cell migration by modulating focal adhesions. Molecular and cellular biology, 2006, Volume: 26, Issue:3 Topics: Animals; Carrier Proteins; Cell Movement; Cells, Cultured; Enzyme Activation; Focal Adhesion Protein-Tyrosine Kinases; Focal Adhesions; Glycogen Synthase Kinase 3; Humans; Neoplasm Invasiveness; Neoplasms; Paxillin; Phosphoric Monoester Hydrolases; Protein Interaction Mapping; Proto-Oncogene Proteins c-akt; RNA Interference	2006
Protease-activated receptor-1 (hPar1), a survival factor eliciting tumor progression. Molecular cancer research : MCR, 2007, Volume: 5, Issue:3 Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Bcl-2-Like Protein 11; Cell Line, Tumor; Cell Survival; Disease Progression; DNA, Antisense; Gene Expression Regulation, Neoplastic; Humans; Membrane Proteins; Mice; Mice, Nude; Neoplasm Invasiveness; Neoplasm Transplantation; Neoplasms; Paxillin; Phosphorylation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptor, PAR-1	2007
Regulation of TM4SF5-mediated tumorigenesis through induction of cell detachment and death by tiarellic acid. Biochimica et biophysica acta, 2008, Volume: 1783, Issue:9 Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Adhesion; Cell Line, Tumor; Crk-Associated Substrate Protein; Female; Focal Adhesion Protein-Tyrosine Kinases; Focal Adhesions; Humans; Membrane Proteins; Mice; Mice, Nude; Neoplasms; Paxillin; Triterpenes	2008
Monocyte cells and cancer cells express novel paxillin isoforms with different binding properties to focal adhesion proteins. The Journal of biological chemistry, 1997, Mar-14, Volume: 272, Issue:11 Topics: Cell Adhesion Molecules; Cytoskeletal Proteins; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Molecular Sequence Data; Monocytes; Neoplasms; Paxillin; Phosphoproteins; Protein Binding; Protein-Tyrosine Kinases; Tumor Cells, Cultured; Vinculin	1997