Page last updated: 2024-08-26

paxilline and Neoplasm Metastasis

paxilline has been researched along with Neoplasm Metastasis in 53 studies

Research

Studies (53)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	5 (9.43)	18.2507
2000's	16 (30.19)	29.6817
2010's	28 (52.83)	24.3611
2020's	4 (7.55)	2.80

Authors

Authors	Studies
Bai, Y; Cao, Z; Chen, X; Cheng, W; Cui, H; Guan, XY; Huang, L; Liu, M; Liu, S; Ma, L; Ma, NF; Mo, Y; Qi, L; Wang, G; Zhang, X	1
Chang, TT; Chen, CL; Chen, WS; Fu, CW; Hsiao, PW; Li, WS; Tsai, HE	1
Hu, J; Quan, HY; Song, M	1
Ahnlide, JK; Axelson, H; Englund, E; Kanzaki, R; Kjellman, P; Li, Z; Lindgren, D; Madsen, CD; Pietras, K; Prinz, CN; Rodriguez-Cupello, C; Saggioro, M; Swaminathan, V; Wang, S	1
Barnes, JM; Bell, ES; Cassereau, L; Chang, AC; Davidson, MW; DuFort, CC; Dunn, AR; Kai, F; Lakins, JN; Lammerding, J; McGregor, AL; Mekhdjian, AH; Odde, DJ; Ou, G; Pickup, MW; Prahl, LS; Przybyla, LM; Rubashkin, MG; Tan, SJ; Weaver, VM; Ye, X	1
Alaoui-Jamali, MA; Bijian, K; Chang, CH; Dahabieh, MS; Miller, WH; Qiu, D; Saad, A; Su, J	1
Chen, L; Li, J; Liu, Q; Qi, X; Qiu, H; Tang, M; Wang, J; Wang, Y; Yu, J	1
Ding, J; Fu, XH; Geng, MY; Huang, X; Sun, DN; Wei, RR; Yan, J; Yang, H; Zhang, X; Zheng, XL	1
Chen, XP; Lu, JJ; Luo, WW; Wang, YT; Zhao, WW	1
Chang, YS; Chung, AK; Hsu, T; Hsueh, C; Jiang, SS; Liu, SC; Liu, YP; OuYang, CN; Tsang, NM; Yuh, CH	1
Pal, M	1
Díaz, J; Leyton, L; Mendoza, P; Ortiz, R; Quest, AF; Stupack, D; Torres, VA	1
Akita, K; Furukawa, K; Hamamura, K; Matsumoto, Y; Nakada, H; Okajima, T; Tsuchida, A; Urano, T; Zhang, Q	1
Kong, CZ; Wang, Y; Zhang, YX; Zhang, Z; Zhu, YY	1
Cao, R; Liu, T; Meng, Z; Wang, X; Wang, Y; Yang, Z	1
Chan, SH; Chang, JW; Cheng, AJ; Chiang, SL; Chiang, WF; Huang, WC; Jang, TH; Juang, JL; Ko, YC; Liao, CT; Lu, YC; Shieh, TY; Wang, HC; Wang, LH; Yen, TC	1
de Bock, GH; Li, Q; Lu, W; Shen, X; Wei, W; Zhou, H	1
Chen, H; Jiang, L; Wang, P	1
Aissaoui, H; Bordet, JC; Boucharaba, A; Boukerche, H; Négrier, C; Prévost, C; Sanhadji, K	1
Choi, J; Kang, M; Kim, D; Kim, DG; Kim, HJ; Kim, S; Kim, SY; Kim, TY; Kwak, TK; Kwon, NH; Lee, D; Lee, GH; Lee, JW; Lee, MS; Nam, SH; Park, SH; Ryu, J; Song, HE; Thiery, JP	1
Aoyama, H; Ferreira, CV; Fuhler, GM; Hoekstra, E; Hoogland, AM; Jenster, G; Pelizzaro-Rocha, K; Peppelenbosch, MP; Ruela-de-Sousa, RR; Souza Queiroz, KC; Stubbs, AP; van Leenders, GJLH	1
Hu, XJ; Li, Y; Liu, CM; Xiong, XY	1
Cemeli, T; Colomina, N; Dolcet, X; Fernández-Hernández, R; Ferrezuelo, F; Fusté, NP; Garí, E; Mirantes, C; Pedraza, N; Rafel, M; Torres-Rosell, J	1
Chen, H; Collier, C; Drake, LE; Macleod, KF; Mowers, EE; Mui, S; Sharifi, MN; Zamora, M	1
Macleod, KF; Mowers, EE; Sharifi, MN	1
Ando, K; Kaneda, T; Kasahara, T; Oshio, T; Sasaki, Y; Sonoda, Y; Suzuki, T; Tago, M	1
Chen, ZN; Jiang, JL; Tang, J; Wu, YM; Yang, XM; Zhao, P	1
Spiczka, KS; Yeaman, C	1
Haura, EB; Kim, LC; Song, L	1
Lu, Z; Zheng, Y	1
Cai, H; Li, SL; Tang, WX; Zhang, T	1
Chen, CC; Chen, PH; Pai, HC; Peng, CY; Teng, CM; Yang, CR	1
Deakin, NO; Turner, CE	1
Balraj, G; Chang, TT; Chen, JY; Cheng, HC; Huang, SM; Juan, HF; Li, WS; Sun, YC; Tang, YA; Wang, SC; Wang, YC; Wu, KW; Wu, LW	1
Chang, CC; Chang, KJ; Chen, CN; Chen, ST; Hsu, WM; Lee, H; Lu, YC; Wang, B	1
Chang, CH; Chang, HW; Chen, CS; Chen, LC; Ho, CT; Ho, YS; Huang, CS; Lee, CH; Lee, WS; Lin, HW; Tu, SH; Wu, CH	1
Chen, DL; Kang, TB; Li, YH; Luo, HY; Qiu, MZ; Ren, C; Wang, DS; Wang, FH; Wang, ZQ; Wu, WJ; Xu, RH; Zeng, ZL; Zhang, DS	1
Liu, SW; Meisinger, J; Young, MR	1
Adamson, ED; Hahn, KM; Junger, S; Pertz, O; Subauste, MC; Turner, CE	1
Enns, A; Haier, J; Korb, T; Nicolson, GL; Schlüter, K; Senninger, N; Spiegel, HU	1
Boyd, DD; Chiosea, S; Fischer, AH; Hill, DA; Imbalzano, AN; Jamaluddin, S; Nickerson, JA; Roy, K	1
Enns, A; Fisch, KM; Gassmann, P; Haier, J; Nicolson, GL; von Sengbusch, A	1
Azuma, K; Inoue, S; Ouchi, Y; Sakai, R; Tanaka, M; Uekita, T; Yokota, J	1
Ching, YP; Jin, DY; Lee, MF; Leong, VY; Ng, IO; Xu, HT	1
Babu, MS; Cha, ST; Chang, KJ; Chen, CN; Chen, MW; Chen, PS; Chuang, SE; Hong, CC; Hua, KT; Kuo, ML; Lee, PH; Su, JL; Wang, MY; Wu, SN; Wu, YL	1
Che, MI; Chen, HY; Huang, HC; Huang, J; Huang, MC; Liang, JT; Lin, NY; Lin, WC; Shen, TL	1
Basson, MD; Craig, DH; Downey, C	1
Chambers, AF; Denhardt, DT	1
Cooper, DR; Jenq, W; Ramirez, G	1
Hioki, K; Kameshita, I; Mohri, T; Suzuki, S; Takatani, S; Tokunaga, R	1
Newell, SW; Perchellet, EM; Perchellet, JP; Ulug, ET	1
Kreuser, ED; Musatkina, E; Rodina, A; Schramm, K; Tatosyan, A; Tavitian, A	1
Blume-Jensen, P; Hunter, T; Jiang, G; Lu, Z	1

Reviews

2 review(s) available for paxilline and Neoplasm Metastasis

Article	Year
Src kinases as therapeutic targets for cancer. Nature reviews. Clinical oncology, 2009, Volume: 6, Issue:10 Topics: Actins; Animals; Cell Adhesion; Cell Movement; Cell Proliferation; Cell Survival; Clinical Trials as Topic; Crk-Associated Substrate Protein; Drug Evaluation, Preclinical; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation, Neoplastic; Genes, ras; GTPase-Activating Proteins; Humans; Integrins; MAP Kinase Signaling System; Neoplasm Metastasis; Neoplasms; Paxillin; Protein Structure, Tertiary; Receptor Protein-Tyrosine Kinases; Signal Transduction; src-Family Kinases; Time Factors; Transcription Factors	2009
Overcoming obstacles to metastasis--defenses against host defenses: osteopontin (OPN) as a shield against attack by cytotoxic host cells. Journal of cellular biochemistry, 1994, Volume: 56, Issue:1 Topics: Amino Acid Oxidoreductases; Animals; Cell Adhesion; Cell Adhesion Molecules; Cytoskeletal Proteins; Endothelium, Vascular; Gene Expression; Humans; Integrins; Macrophages; Models, Biological; Neoplasm Metastasis; Neoplasms; Nitric Oxide Synthase; Osteopontin; Paxillin; Phosphoproteins; Phosphorylation; Receptors, Cytoadhesin; Receptors, Vitronectin; Sialoglycoproteins; Signal Transduction	1994

Article

Year

Src kinases as therapeutic targets for cancer.

Nature reviews. Clinical oncology, 2009, Volume: 6, Issue:10

Topics: Actins; Animals; Cell Adhesion; Cell Movement; Cell Proliferation; Cell Survival; Clinical Trials as Topic; Crk-Associated Substrate Protein; Drug Evaluation, Preclinical; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation, Neoplastic; Genes, ras; GTPase-Activating Proteins; Humans; Integrins; MAP Kinase Signaling System; Neoplasm Metastasis; Neoplasms; Paxillin; Protein Structure, Tertiary; Receptor Protein-Tyrosine Kinases; Signal Transduction; src-Family Kinases; Time Factors; Transcription Factors

2009

Overcoming obstacles to metastasis--defenses against host defenses: osteopontin (OPN) as a shield against attack by cytotoxic host cells.

Journal of cellular biochemistry, 1994, Volume: 56, Issue:1

Topics: Amino Acid Oxidoreductases; Animals; Cell Adhesion; Cell Adhesion Molecules; Cytoskeletal Proteins; Endothelium, Vascular; Gene Expression; Humans; Integrins; Macrophages; Models, Biological; Neoplasm Metastasis; Neoplasms; Nitric Oxide Synthase; Osteopontin; Paxillin; Phosphoproteins; Phosphorylation; Receptors, Cytoadhesin; Receptors, Vitronectin; Sialoglycoproteins; Signal Transduction

1994

Other Studies

51 other study(ies) available for paxilline and Neoplasm Metastasis

Article	Year
CHD1L augments autophagy-mediated migration of hepatocellular carcinoma through targeting ZKSCAN3. Cell death & disease, 2021, 10-15, Volume: 12, Issue:10 Topics: Animals; Autophagy; Autophagy-Related Protein 5; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; DNA Helicases; DNA-Binding Proteins; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Liver Neoplasms; Mice, Inbred BALB C; Mice, Nude; Microtubule-Associated Proteins; Neoplasm Metastasis; Paxillin; RNA, Small Interfering; Transcription Factors; Transcription, Genetic	2021
Sialyltransferase Inhibitors Suppress Breast Cancer Metastasis. Journal of medicinal chemistry, 2021, 01-14, Volume: 64, Issue:1 Topics: Animals; Animals, Genetically Modified; Breast Neoplasms; Catalysis; Cell Line, Tumor; Enzyme Inhibitors; Female; Focal Adhesion Protein-Tyrosine Kinases; Glycoproteins; Humans; Integrins; Isoenzymes; Molecular Docking Simulation; Neoplasm Metastasis; NF-kappa B; Paxillin; Phosphorylation; Sialyltransferases; Signal Transduction; Talin; Zebrafish	2021
Abnormal expression of FAK and paxillin correlates with oral cancer invasion and metastasis. Acta biochimica Polonica, 2021, Apr-16, Volume: 68, Issue:2 Topics: Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Focal Adhesion Protein-Tyrosine Kinases; Humans; Matrix Metalloproteinase 11; Mouth Neoplasms; Neoplasm Invasiveness; Neoplasm Metastasis; Paxillin; RNA Interference; Side-Population Cells	2021
CCM3 is a gatekeeper in focal adhesions regulating mechanotransduction and YAP/TAZ signalling. Nature cell biology, 2021, Volume: 23, Issue:7 Topics: Adaptor Proteins, Signal Transducing; Animals; Apoptosis Regulatory Proteins; Breast Neoplasms; Cancer-Associated Fibroblasts; Cell Communication; Cell Differentiation; Cell Line, Tumor; Female; Focal Adhesion Kinase 1; Focal Adhesions; Gene Expression Regulation, Neoplastic; Humans; Intracellular Signaling Peptides and Proteins; Mechanotransduction, Cellular; Membrane Proteins; Mesenchymal Stem Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Paxillin; Phosphorylation; Protein Binding; Proto-Oncogene Proteins; src-Family Kinases; Stress, Mechanical; Transcription Factors; Transcriptional Coactivator with PDZ-Binding Motif Proteins; YAP-Signaling Proteins	2021
Integrin-mediated traction force enhances paxillin molecular associations and adhesion dynamics that increase the invasiveness of tumor cells into a three-dimensional extracellular matrix. Molecular biology of the cell, 2017, Jun-01, Volume: 28, Issue:11 Topics: Breast; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Extracellular Matrix; Female; Focal Adhesion Protein-Tyrosine Kinases; Humans; Integrins; Neoplasm Metastasis; Paxillin; Phosphorylation; Signal Transduction	2017
Endosomal sorting and c-Cbl targeting of paxillin to autophagosomes regulate cell-matrix adhesion turnover in human breast cancer cells. Oncotarget, 2017, May-09, Volume: 8, Issue:19 Topics: Autophagosomes; Autophagy; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Disease Progression; Endosomes; Extracellular Matrix; Gene Knockdown Techniques; Humans; Microtubule-Associated Proteins; Neoplasm Metastasis; Paxillin; Phosphorylation; Protein Binding; Proteolysis; Proto-Oncogene Proteins c-cbl; rab GTP-Binding Proteins; rab7 GTP-Binding Proteins; Signal Transduction	2017
The overexpression of PXN promotes tumor progression and leads to radioresistance in cervical cancer. Future oncology (London, England), 2018, Volume: 14, Issue:3 Topics: Adult; Aged; Animals; Apoptosis; Case-Control Studies; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Disease Progression; Female; Gene Expression; Gene Knockdown Techniques; Humans; Mice; Middle Aged; Neoplasm Grading; Neoplasm Metastasis; Neoplasm Staging; Paxillin; Prognosis; Radiation Tolerance; Uterine Cervical Neoplasms; Xenograft Model Antitumor Assays	2018
CTC clusters induced by heparanase enhance breast cancer metastasis. Acta pharmacologica Sinica, 2018, Volume: 39, Issue:8 Topics: Animals; Breast Neoplasms; Cell Adhesion; Cell Aggregation; Cell Line, Tumor; Female; Focal Adhesion Kinase 1; Glucuronidase; Humans; Intercellular Adhesion Molecule-1; Mice, Inbred BALB C; Neoplasm Metastasis; Neoplastic Cells, Circulating; Paxillin; src-Family Kinases; Up-Regulation	2018
Cucurbitacin B suppresses metastasis mediated by reactive oxygen species (ROS) via focal adhesion kinase (FAK) in breast cancer MDA-MB-231 cells. Chinese journal of natural medicines, 2018, Volume: 16, Issue:1 Topics: Acetylcysteine; Antineoplastic Agents; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Collagen Type I; Dose-Response Relationship, Drug; Down-Regulation; Female; Fibronectins; Focal Adhesion Kinase 1; Humans; Neoplasm Invasiveness; Neoplasm Metastasis; Paxillin; Phosphorylation; Reactive Oxygen Species; Triterpenes	2018
Cytoplasmic LIF reprograms invasive mode to enhance NPC dissemination through modulating YAP1-FAK/PXN signaling. Nature communications, 2018, 11-30, Volume: 9, Issue:1 Topics: Adaptor Proteins, Signal Transducing; Adult; Aged; Aged, 80 and over; Animals; Blotting, Western; Epithelial-Mesenchymal Transition; Female; Focal Adhesion Kinase 1; Human Umbilical Vein Endothelial Cells; Humans; Immunohistochemistry; Leukemia Inhibitory Factor; Male; Mice; Mice, SCID; Middle Aged; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Invasiveness; Neoplasm Metastasis; Paxillin; Phosphoproteins; Receptors, OSM-LIF; Signal Transduction; Transcription Factors; Xenograft Model Antitumor Assays; YAP-Signaling Proteins; Young Adult	2018
Tumor metastasis suppressor functions of Ets transcription factor through integrin β3-mediated signaling pathway. Journal of cellular physiology, 2019, Volume: 234, Issue:11 Topics: Cell Adhesion; Cell Line, Tumor; Cell Movement; Cytoskeleton; Gene Expression Regulation, Neoplastic; Humans; Integrin beta3; Male; Neoplasm Metastasis; Paxillin; PC-3 Cells; Prostate; Prostatic Neoplasms; Proto-Oncogene Proteins c-ets; Signal Transduction; Talin	2019
Rab5 activation promotes focal adhesion disassembly, migration and invasiveness in tumor cells. Journal of cell science, 2013, Sep-01, Volume: 126, Issue:Pt 17 Topics: Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Enzyme Activation; Female; Focal Adhesions; Humans; Lung Neoplasms; Neoplasm Invasiveness; Neoplasm Metastasis; Paxillin; rab5 GTP-Binding Proteins; RNA Interference; RNA, Small Interfering; Vinculin	2013
Trimeric Tn antigen on syndecan 1 produced by ppGalNAc-T13 enhances cancer metastasis via a complex formation with integrin α5β1 and matrix metalloproteinase 9. The Journal of biological chemistry, 2013, Aug-16, Volume: 288, Issue:33 Topics: Animals; Antigens, Tumor-Associated, Carbohydrate; Base Sequence; Carcinoma, Lewis Lung; Cell Adhesion; Fibronectins; Focal Adhesion Protein-Tyrosine Kinases; Gene Knockdown Techniques; Integrin alpha5beta1; Matrix Metalloproteinase 9; Membrane Microdomains; Mice; Models, Biological; Molecular Sequence Data; N-Acetylgalactosaminyltransferases; Neoplasm Invasiveness; Neoplasm Metastasis; Paxillin; Phosphotyrosine; Polypeptide N-acetylgalactosaminyltransferase; Protein Multimerization; Signal Transduction; Syndecan-1	2013
Loss of P53 facilitates invasion and metastasis of prostate cancer cells. Molecular and cellular biochemistry, 2013, Volume: 384, Issue:1-2 Topics: Cell Adhesion; Cell Line, Tumor; Cell Movement; Cortactin; Cytoskeleton; Epithelial-Mesenchymal Transition; Extracellular Signal-Regulated MAP Kinases; Focal Adhesion Kinase 1; Humans; JNK Mitogen-Activated Protein Kinases; Male; Matrix Metalloproteinase 14; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Neoplasm Metastasis; Paxillin; Phosphorylation; Prostatic Neoplasms; RNA Interference; RNA, Small Interfering; src-Family Kinases; Tumor Suppressor Protein p53; Wound Healing	2013
Inhibitor of 5-lipoxygenase, zileuton, suppresses prostate cancer metastasis by upregulating E-cadherin and paxillin. Urology, 2013, Volume: 82, Issue:6 Topics: Animals; Arachidonate 5-Lipoxygenase; Cadherins; Cell Migration Assays; Enzyme-Linked Immunosorbent Assay; Humans; Hydroxyeicosatetraenoic Acids; Hydroxyurea; Immunohistochemistry; Lipoxygenase Inhibitors; Male; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Paxillin; Prostatic Neoplasms; Up-Regulation	2013
miRNA-491-5p and GIT1 serve as modulators and biomarkers for oral squamous cell carcinoma invasion and metastasis. Cancer research, 2014, Feb-01, Volume: 74, Issue:3 Topics: Adaptor Proteins, Signal Transducing; Animals; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Cycle Proteins; Cell Line, Tumor; Cell Movement; Disease Models, Animal; ErbB Receptors; Focal Adhesion Kinase 1; Focal Adhesions; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; MicroRNAs; Mouth Neoplasms; Neoplasm Invasiveness; Neoplasm Metastasis; Paxillin; Proteolysis; RNA Interference; Signal Transduction	2014
The roles of Wnt5a, JNK and paxillin in the occurrence of metastasis of pancreatic adenocarcinoma. International journal of clinical oncology, 2014, Volume: 19, Issue:6 Topics: Adenocarcinoma; Female; Gene Expression Regulation, Neoplastic; Humans; Lymph Nodes; Male; Middle Aged; Mitogen-Activated Protein Kinase 8; Neoplasm Metastasis; Pancreatic Neoplasms; Paxillin; Proto-Oncogene Proteins; Wnt Proteins; Wnt-5a Protein	2014
Overexpression of FOXM1 is associated with metastases of nasopharyngeal carcinoma. Upsala journal of medical sciences, 2014, Volume: 119, Issue:4 Topics: Adult; Aged; Carcinoma; Carrier Proteins; Cell Line, Tumor; Cell Movement; Cytoskeletal Proteins; Female; Forkhead Box Protein M1; Forkhead Transcription Factors; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Microfilament Proteins; Middle Aged; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Invasiveness; Neoplasm Metastasis; Paxillin; Thiostrepton	2014
MDA-9/syntenin is essential for factor VIIa-induced signaling, migration, and metastasis in melanoma cells. The Journal of biological chemistry, 2015, Feb-06, Volume: 290, Issue:6 Topics: Animals; cdc42 GTP-Binding Protein; Cell Line, Tumor; Cell Movement; Factor VIIa; Factor X; Gene Expression Regulation, Neoplastic; Humans; JNK Mitogen-Activated Protein Kinases; Matrix Metalloproteinase 2; Melanoma; Mice; Neoplasm Metastasis; NF-kappa B; NIH 3T3 Cells; Paxillin; PDZ Domains; Protein Binding; rac1 GTP-Binding Protein; Receptor, PAR-1; Signal Transduction; src-Family Kinases; Syntenins; Up-Regulation	2015
Noncanonical roles of membranous lysyl-tRNA synthetase in transducing cell-substrate signaling for invasive dissemination of colon cancer spheroids in 3D collagen I gels. Oncotarget, 2015, Aug-28, Volume: 6, Issue:25 Topics: Animals; Cadherins; Cell Adhesion; Cell Line, Tumor; Collagen Type I; Colonic Neoplasms; Cytosol; Extracellular Matrix; Female; Fluorescence Resonance Energy Transfer; Fluorescent Antibody Technique, Indirect; HCT116 Cells; Humans; Lysine-tRNA Ligase; Mice; Neoplasm Metastasis; Paxillin; Phosphorylation; Protein Biosynthesis; Signal Transduction	2015
Low-Molecular-Weight Protein Tyrosine Phosphatase Predicts Prostate Cancer Outcome by Increasing the Metastatic Potential. European urology, 2016, Volume: 69, Issue:4 Topics: Aged; Anoikis; Biomarkers, Tumor; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chi-Square Distribution; Focal Adhesion Kinase 1; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Molecular Weight; Multivariate Analysis; Neoplasm Metastasis; Neoplasm Recurrence, Local; Patient Selection; Paxillin; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Prostatectomy; Prostatic Neoplasms; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins; Risk Assessment; Risk Factors; Time Factors; Tissue Array Analysis; Transfection; Up-Regulation; Watchful Waiting	2016
Inhibitory Effects of Enterolactone on Growth and Metastasis in Human Breast Cancer. Nutrition and cancer, 2015, Volume: 67, Issue:8 Topics: 4-Butyrolactone; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclins; Cytoskeleton; Focal Adhesion Kinase 1; Forkhead Box Protein M1; Forkhead Transcription Factors; Gene Expression; Humans; Ki-67 Antigen; Lignans; Neoplasm Invasiveness; Neoplasm Metastasis; Paxillin; Proliferating Cell Nuclear Antigen; RNA, Messenger; S Phase; Signal Transduction	2015
Cytoplasmic cyclin D1 regulates cell invasion and metastasis through the phosphorylation of paxillin. Nature communications, 2016, 05-16, Volume: 7 Topics: Animals; Cell Line, Tumor; Cell Membrane; Cyclin D1; Cyclin-Dependent Kinase 4; Cytoplasm; Down-Regulation; Fibroblasts; Gene Knockdown Techniques; HEK293 Cells; Humans; Mice; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms; Paxillin; Phosphorylation; Phosphoserine; Protein Binding; rac1 GTP-Binding Protein; Rats; Substrate Specificity	2016
Autophagy Promotes Focal Adhesion Disassembly and Cell Motility of Metastatic Tumor Cells through the Direct Interaction of Paxillin with LC3. Cell reports, 2016, 05-24, Volume: 15, Issue:8 Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Autophagosomes; Autophagy; Autophagy-Related Proteins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Focal Adhesions; Gene Knockdown Techniques; Mice, Inbred BALB C; Microtubule-Associated Proteins; Neoplasm Metastasis; Neoplasms; Paxillin; Protein Binding; Protein Stability; Protein Transport; src-Family Kinases	2016
Novel insights into how autophagy regulates tumor cell motility. Autophagy, 2016, Volume: 12, Issue:9 Topics: Amino Acid Motifs; Autophagy; Cell Adhesion; Cell Movement; Cytoskeletal Proteins; Cytoskeleton; Focal Adhesions; Humans; Neoplasm Metastasis; Neoplasms; Paxillin; Phosphorylation; Signal Transduction	2016
Mutation of Y925F in focal adhesion kinase (FAK) suppresses melanoma cell proliferation and metastasis. Cancer letters, 2008, Nov-08, Volume: 270, Issue:2 Topics: Animals; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Extracellular Matrix; Extracellular Signal-Regulated MAP Kinases; Focal Adhesion Kinase 1; Gene Expression Regulation, Neoplastic; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mutation; Neoplasm Invasiveness; Neoplasm Metastasis; Paxillin; Phosphorylation; Transfection; Vascular Endothelial Growth Factor A	2008
Overexpression of HAb18G/CD147 promotes invasion and metastasis via alpha3beta1 integrin mediated FAK-paxillin and FAK-PI3K-Ca2+ pathways. Cellular and molecular life sciences : CMLS, 2008, Volume: 65, Issue:18 Topics: Basigin; Calcium; Carcinoma, Hepatocellular; Cell Line, Tumor; Cytoskeleton; Focal Adhesion Protein-Tyrosine Kinases; Focal Adhesions; Gene Silencing; Humans; Integrin alpha3beta1; Liver Neoplasms; Neoplasm Invasiveness; Neoplasm Metastasis; Paxillin; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors	2008
Ral-regulated interaction between Sec5 and paxillin targets Exocyst to focal complexes during cell migration. Journal of cell science, 2008, Sep-01, Volume: 121, Issue:Pt 17 Topics: Animals; Cadherins; Cell Line, Tumor; Cell Movement; Cell Polarity; Cell Proliferation; Exocytosis; Focal Adhesions; Humans; Male; Neoplasm Metastasis; Paxillin; Prostatic Neoplasms; Protein Binding; Protein Subunits; Protein Transport; Pseudopodia; ral GTP-Binding Proteins; Rats; Secretory Vesicles; Vesicular Transport Proteins	2008
Paradoxical roles of FAK in tumor cell migration and metastasis. Cell cycle (Georgetown, Tex.), 2009, Nov-01, Volume: 8, Issue:21 Topics: Animals; Cell Adhesion; Cell Movement; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation; Genes, ras; Humans; Integrins; Mice; Neoplasm Metastasis; Neoplasms; Paxillin; Phosphorylation; Receptor Protein-Tyrosine Kinases; Signal Transduction	2009
[Expression of paxillin in breast cancer cell with high and low metastatic potentiality]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2010, Volume: 41, Issue:1 Topics: Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Female; Humans; Neoplasm Metastasis; Paxillin	2010
Denbinobin suppresses breast cancer metastasis through the inhibition of Src-mediated signaling pathways. The Journal of nutritional biochemistry, 2011, Volume: 22, Issue:8 Topics: Animals; Anthraquinones; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; Crk-Associated Substrate Protein; Female; Focal Adhesion Kinase 1; Humans; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Paxillin; Phenanthrenes; Phosphorylation; Signal Transduction; src-Family Kinases; Transfection	2011
Distinct roles for paxillin and Hic-5 in regulating breast cancer cell morphology, invasion, and metastasis. Molecular biology of the cell, 2011, Feb-01, Volume: 22, Issue:3 Topics: Animals; Breast Neoplasms; Cattle; Cell Adhesion; Cell Line, Tumor; Cell Movement; Extracellular Matrix; Female; Humans; Intracellular Signaling Peptides and Proteins; LIM Domain Proteins; Lung Neoplasms; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Invasiveness; Neoplasm Metastasis; Paxillin; rhoA GTP-Binding Protein; Signal Transduction	2011
A novel sialyltransferase inhibitor suppresses FAK/paxillin signaling and cancer angiogenesis and metastasis pathways. Cancer research, 2011, Jan-15, Volume: 71, Issue:2 Topics: Animals; Cell Line; Cell Line, Tumor; Focal Adhesion Kinase 1; Humans; Integrins; Lithocholic Acid; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Neovascularization, Pathologic; Paxillin; Proteomics; Sialyltransferases; Signal Transduction	2011
Changes in tumor growth and metastatic capacities of J82 human bladder cancer cells suppressed by down-regulation of calreticulin expression. The American journal of pathology, 2011, Volume: 179, Issue:3 Topics: Animals; Calreticulin; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Focal Adhesion Kinase 1; Humans; Mice; Mice, Nude; Mice, SCID; Neoplasm Metastasis; Neoplasm Transplantation; Paxillin; Phosphorylation; Urinary Bladder Neoplasms	2011
Human breast cancer cell metastasis is attenuated by lysyl oxidase inhibitors through down-regulation of focal adhesion kinase and the paxillin-signaling pathway. Breast cancer research and treatment, 2012, Volume: 134, Issue:3 Topics: Adult; Aged; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Down-Regulation; Enzyme Inhibitors; Female; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression; Humans; Hydrogen Peroxide; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Paxillin; Prognosis; Protein-Lysine 6-Oxidase; RNA, Messenger; Signal Transduction; src-Family Kinases	2012
Overexpression of paxillin induced by miR-137 suppression promotes tumor progression and metastasis in colorectal cancer. Carcinogenesis, 2013, Volume: 34, Issue:4 Topics: Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Disease Progression; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Paxillin; Prognosis; RNA Interference; RNA, Messenger; RNA, Small Interfering; Transplantation, Heterologous	2013
Protein phosphatase-2A restricts migration of Lewis lung carcinoma cells by modulating the phosphorylation of focal adhesion proteins. International journal of cancer, 2003, Jan-01, Volume: 103, Issue:1 Topics: Animals; Birds; Blotting, Western; Carcinoma, Lewis Lung; Cell Movement; Cytoskeletal Proteins; Down-Regulation; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Focal Adhesions; Genes, src; Humans; Mice; Mutation; Neoplasm Metastasis; Neoplasm Proteins; Paxillin; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Precipitin Tests; Protein Phosphatase 2; Protein Processing, Post-Translational; Protein-Tyrosine Kinases	2003
Vinculin modulation of paxillin-FAK interactions regulates ERK to control survival and motility. The Journal of cell biology, 2004, May-10, Volume: 165, Issue:3 Topics: Animals; Apoptosis; Binding Sites; Cell Adhesion; Cell Movement; Cell Survival; Cytoskeletal Proteins; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Mice; Mitogen-Activated Protein Kinases; Mutation; Neoplasm Metastasis; Neoplastic Stem Cells; Paxillin; Peptide Fragments; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Transfection; Up-Regulation; Vinculin	2004
Integrity of actin fibers and microtubules influences metastatic tumor cell adhesion. Experimental cell research, 2004, Sep-10, Volume: 299, Issue:1 Topics: Actin Cytoskeleton; Animals; Cell Adhesion; Cytoskeletal Proteins; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Liver; Male; Microcirculation; Microtubules; Neoplasm Metastasis; Neoplasms; Paxillin; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Signal Transduction; Tubulin; Tubulin Modulators; Tumor Cells, Cultured	2004
Inducible changes in cell size and attachment area due to expression of a mutant SWI/SNF chromatin remodeling enzyme. Journal of cell science, 2004, Nov-15, Volume: 117, Issue:Pt 24 Topics: Actins; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Blotting, Northern; Blotting, Western; Cell Adhesion; Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Nucleus; Cell Size; Chromatin; Collagen; Cytoskeletal Proteins; Cytoskeleton; DNA Helicases; DNA, Complementary; Dose-Response Relationship, Drug; Drug Combinations; Focal Adhesions; Gene Expression Regulation; Heterozygote; Humans; Laminin; Mice; Mutation; Neoplasm Metastasis; Nuclear Proteins; Paxillin; Phosphoproteins; Protein Binding; Protein Structure, Tertiary; Proteoglycans; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; RNA, Messenger; Time Factors; Transcription Factors	2004
Focal adhesion kinase regulates metastatic adhesion of carcinoma cells within liver sinusoids. The American journal of pathology, 2005, Volume: 166, Issue:2 Topics: Animals; Carcinoma; Carcinoma, Hepatocellular; Cell Adhesion; Cell Line, Tumor; Collagen; Colon; Cytoskeletal Proteins; Dose-Response Relationship, Drug; Endothelium, Vascular; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Immunoprecipitation; Liver; Liver Neoplasms; Male; Microcirculation; Microscopy, Fluorescence; Neoplasm Metastasis; Neoplasms; Oligonucleotides; Paxillin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Time Factors; Transfection; Tyrosine	2005
Tyrosine phosphorylation of paxillin affects the metastatic potential of human osteosarcoma. Oncogene, 2005, Jul-14, Volume: 24, Issue:30 Topics: Animals; Cell Line, Tumor; Cell Movement; Cytoskeletal Proteins; Humans; Neoplasm Metastasis; Osteosarcoma; Paxillin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Proteins; Retinoblastoma-Like Protein p130; RNA Interference; src-Family Kinases	2005
P21-activated protein kinase is overexpressed in hepatocellular carcinoma and enhances cancer metastasis involving c-Jun NH2-terminal kinase activation and paxillin phosphorylation. Cancer research, 2007, Apr-15, Volume: 67, Issue:8 Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Enzyme Activation; Humans; JNK Mitogen-Activated Protein Kinases; Liver Neoplasms; Neoplasm Metastasis; p21-Activated Kinases; Paxillin; Phosphorylation; Protein Serine-Threonine Kinases	2007
CTGF enhances the motility of breast cancer cells via an integrin-alphavbeta3-ERK1/2-dependent S100A4-upregulated pathway. Journal of cell science, 2007, Jun-15, Volume: 120, Issue:Pt 12 Topics: Actins; Animals; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Shape; Connective Tissue Growth Factor; Enzyme Activation; Female; Focal Adhesions; Gene Expression Regulation, Neoplastic; Humans; Immediate-Early Proteins; Integrin alphaVbeta3; Intercellular Signaling Peptides and Proteins; Mice; Mice, Nude; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neoplasm Metastasis; Oligonucleotides, Antisense; Paxillin; S100 Calcium-Binding Protein A4; S100 Proteins; Signal Transduction	2007
Beta1,4-N-acetylgalactosaminyltransferase III enhances malignant phenotypes of colon cancer cells. Molecular cancer research : MCR, 2007, Volume: 5, Issue:6 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Nude; N-Acetylgalactosaminyltransferases; Neoplasm Invasiveness; Neoplasm Metastasis; Paxillin; Phenotype	2007
Pressure activates colon cancer cell adhesion via paxillin phosphorylation, Crk, Cas, and Rac1. Cellular and molecular life sciences : CMLS, 2008, Volume: 65, Issue:9 Topics: Actinin; Cell Adhesion; Cell Line, Tumor; Colonic Neoplasms; Crk-Associated Substrate Protein; Humans; Neoplasm Metastasis; Paxillin; Phosphorylation; Pressure; Proto-Oncogene Proteins c-crk; rac1 GTP-Binding Protein; RNA Interference; Tumor Cells, Cultured; Tyrosine	2008
Integrin expression on cell adhesion function and up-regulation of P125FAK and paxillin in metastatic renal carcinoma cells. Connective tissue research, 1996, Volume: 34, Issue:3 Topics: Blotting, Western; Cell Adhesion; Cell Adhesion Molecules; Cell Line; Cytoskeletal Proteins; Electrophoresis, Polyacrylamide Gel; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Integrins; Kidney Neoplasms; Neoplasm Metastasis; Nucleic Acid Hybridization; Paxillin; Phosphoproteins; Precipitin Tests; Protein-Tyrosine Kinases; RNA, Messenger; Tumor Cells, Cultured; Up-Regulation	1996
Rapid adhesion and spread of non-adherent colon cancer Colo201 cells induced by the protein kinase inhibitors, K252a and KT5720 and suppression of the adhesion by the immunosuppressants FK506 and cyclosporin A. Cell structure and function, 1998, Volume: 23, Issue:5 Topics: Adenocarcinoma; Carbazoles; Cell Adhesion; Cell Adhesion Molecules; Colonic Neoplasms; Cyclosporine; Cytoskeletal Proteins; Enzyme Inhibitors; Extracellular Matrix; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Immunosuppressive Agents; Indole Alkaloids; Indoles; Integrins; Neoplasm Metastasis; Paxillin; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Pyrroles; Sulfonamides; Tacrolimus; Tumor Cells, Cultured; Tyrosine	1998
Alterations in focal adhesion kinase activity and associated proteins during malignant conversion of mouse keratinocytes. Molecular carcinogenesis, 1999, Volume: 25, Issue:1 Topics: Animals; Blotting, Western; Calcium; Cell Adhesion Molecules; Cell Differentiation; Cell Line; Cell Line, Transformed; Cell Transformation, Neoplastic; Cytoskeletal Proteins; Enzyme Activation; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Immunohistochemistry; Integrin beta1; Keratinocytes; Mice; Neoplasm Metastasis; Papilloma; Paxillin; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Binding; Protein-Tyrosine Kinases; Skin Neoplasms	1999
Phosphorylation of p125FAK and paxillin focal adhesion proteins in src-transformed cells with different metastatic capacity. FEBS letters, 1999, Jul-16, Volume: 455, Issue:1-2 Topics: Animals; Cell Adhesion Molecules; Cell Line, Transformed; Cricetinae; Cytoskeletal Proteins; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Mesocricetus; Neoplasm Metastasis; Paxillin; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases	1999
Epidermal growth factor-induced tumor cell invasion and metastasis initiated by dephosphorylation and downregulation of focal adhesion kinase. Molecular and cellular biology, 2001, Volume: 21, Issue:12 Topics: 3T3 Cells; Alu Elements; Animals; Base Sequence; Cell Adhesion; Cell Movement; Cytoskeletal Proteins; DNA Primers; Down-Regulation; Epidermal Growth Factor; ErbB Receptors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Mice; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Paxillin; Phenotype; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Proteins; Retinoblastoma-Like Protein p130; Tumor Cells, Cultured	2001