paxilline has been researched along with Melanoma in 26 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 3 (11.54) | 18.2507 |
2000's | 10 (38.46) | 29.6817 |
2010's | 12 (46.15) | 24.3611 |
2020's | 1 (3.85) | 2.80 |
Authors | Studies |
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Harada, Y; Isei, T; Kanto, N; Maeda, K; Ohe, S; Ohkawa, Y; Tachibana, K; Taniguchi, N | 1 |
He, Q; Li, M; Liu, J; Rao, J; Tang, X; Wan, D; Wang, X; Wang, Y; Wei, J; Xia, C; Yin, S; Zhang, Z | 1 |
Chen, SH; Hung, WC; Konstantopoulos, K; Lo, YC; Paul, CD; Stroka, KM; Yang, JT | 1 |
Bai, H; Chen, F; Dong, C; Fu, C; Song, E; Song, Y; Wu, C; Ye, Q; Zeng, P; Zhang, P | 1 |
Aissaoui, H; Bordet, JC; Boucharaba, A; Boukerche, H; Négrier, C; Prévost, C; Sanhadji, K | 1 |
Bhuiyan, RH; Furukawa, K; Hamamura, K; Makino, Y; Nakashima, H; Ohkawa, Y; Ohmi, Y; Takei, Y | 1 |
Furukawa, K; Hamamura, K; Miyata, M; Miyazaki, S; Ohkawa, Y | 1 |
Clark, E; Eskandarpour, M; Hansson, J; Huang, F; Reeves, KA | 1 |
Estrada-Bernal, A; Gatlin, JC; Pfenninger, KH; Sunpaweravong, S | 1 |
Elbling, L; Fiebiger, E; Gerner, C; Jäger, W; Kunstfeld, R; Mikula, M; Paulitschke, V; Pehamberger, H; Riemer, AB; Scheiner, O; Schicher, N; Swoboda, A; Szekeres, T; Trimurtulu, G; Venkateswarlu, S | 1 |
Furukawa, K; Hamamura, K; Kambe, M; Miyata, M; Miyazaki, S; Ohkawa, Y; Ohmi, Y; Tajima, O; Yamauchi, Y | 1 |
Dong, Y; Furukawa, K; Hamamura, K; Ikeda, K; Kondo, Y; Matsumoto, Y; Ohmi, Y; Taguchi, R; Yamauchi, Y; Zhang, Q | 1 |
Itokazu, Y; Käkelä, R; Korpi, ER; Somerharju, P; Tajima, N | 1 |
Arellano-Sánchez, N; Bartolomé, RA; Coló, GP; Hernández-Varas, P; Lock, J; Strömblad, S; Teixidó, J | 1 |
Ludwig, FT; Schwab, A; Stock, C | 1 |
Baur, AS; Bräu, T; Dindorf, J; Dreyer, FS; Federico, M; Gross, S; Harrer, T; Johnston, IC; Krätzel, K; Kremmer, E; Lee, JH; Lichtenheld, M; Saksela, K; Schlötzer-Schrehardt, U; Schuler, G; Wittki, S; Zeidler, R | 1 |
Critchley, DR; Giannone, G; Jiang, G; Sheetz, MP; Sutton, DH | 1 |
Ding, M; Fu, X; Fu, YM; Li, YQ; Meadows, GG; Yu, ZX; Zhang, H | 1 |
Furukawa, K; Hamamura, K; Hattori, H; Hattori, T; Hayashi, T; Lloyd, KO; Mizutani, H; Nakano, J; Nakashima, H; Okuda, T; Ueda, M; Urano, T | 1 |
Aixinjueluo, W; Furukawa, K; Hamamura, K | 1 |
Furukawa, K; Hamamura, K; Houjou, T; Mitsudo, K; Nakashima, H; Taguchi, R; Tohnai, I; Ueda, M; Urano, T; Yamamoto, N | 1 |
Furukawa, K; Hamamura, K; Miyazaki, S; Nakashima, H; Ohkawa, Y; Tsuji, M; Ueda, M; Urano, T; Yamamoto, N | 1 |
Aznavoorian, S; Liotta, LA; McClanahan, J; Parsons, J; Stracke, ML | 1 |
Darbon, JM; Malecaze, F; Manenti, S | 1 |
Amemiya, M; Ishizuka, M; Kawada, M; Takeuchi, T | 1 |
Amodeo, DM; Byers, HR; Dekker, SK; Jalbert, NL; Leccia, MT; van der Gaag, EJ | 1 |
1 review(s) available for paxilline and Melanoma
Article | Year |
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Biosignals modulated by tumor-associated carbohydrate antigens: novel targets for cancer therapy.
Topics: Anoikis; Antibodies, Monoclonal; Carcinoma, Small Cell; Cell Line, Tumor; Cell Proliferation; Crk-Associated Substrate Protein; Focal Adhesion Protein-Tyrosine Kinases; Gangliosides; Glycosphingolipids; Humans; Lung Neoplasms; Melanoma; Neoplasm Invasiveness; Paxillin; Phosphorylation; Tyrosine | 2006 |
25 other study(ies) available for paxilline and Melanoma
Article | Year |
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The expression of keratan sulfate in malignant melanoma enhances the adhesion and invasion activity of melanoma cells.
Topics: Cell Line, Tumor; Glycolipids; Humans; Keratan Sulfate; Melanoma; Melanoma, Cutaneous Malignant; Paxillin; Proteoglycans; Skin Neoplasms | 2022 |
Dual receptor recognizing liposomes containing paclitaxel and hydroxychloroquine for primary and metastatic melanoma treatment via autophagy-dependent and independent pathways.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Cell Line; Humans; Hydroxychloroquine; Integrin alphaVbeta3; Liposomes; Lung Neoplasms; Melanoma; Mice, Inbred C57BL; Neuropilin-1; Oligopeptides; Paclitaxel; Paxillin; Phosphatidylethanolamines; Polyethylene Glycols; Receptors, CXCR4 | 2018 |
Distinct signaling mechanisms regulate migration in unconfined versus confined spaces.
Topics: 3T3 Cells; Animals; Cell Line, Tumor; Cell Movement; CHO Cells; Cricetinae; Cricetulus; Focal Adhesions; Heterocyclic Compounds, 4 or More Rings; Humans; Integrin alpha4; Integrin alpha4beta1; Jurkat Cells; Melanoma; Mice; Mutant Proteins; Mutation; Myosin Type II; Neoplasm Invasiveness; Paxillin; Phenotype; Protein Binding; rac1 GTP-Binding Protein; rhoA GTP-Binding Protein; Signal Transduction; Stress Fibers | 2013 |
RacGAP1-driven focal adhesion formation promotes melanoma transendothelial migration through mediating adherens junction disassembly.
Topics: Adherens Junctions; Cell Line, Tumor; Cell Movement; Endothelial Cells; Focal Adhesion Kinase 1; Focal Adhesions; GTPase-Activating Proteins; Human Umbilical Vein Endothelial Cells; Humans; Melanoma; Mutation; Paxillin; Phosphorylation; Protein-Tyrosine Kinases; rhoA GTP-Binding Protein; Transendothelial and Transepithelial Migration | 2015 |
MDA-9/syntenin is essential for factor VIIa-induced signaling, migration, and metastasis in melanoma cells.
Topics: Animals; cdc42 GTP-Binding Protein; Cell Line, Tumor; Cell Movement; Factor VIIa; Factor X; Gene Expression Regulation, Neoplastic; Humans; JNK Mitogen-Activated Protein Kinases; Matrix Metalloproteinase 2; Melanoma; Mice; Neoplasm Metastasis; NF-kappa B; NIH 3T3 Cells; Paxillin; PDZ Domains; Protein Binding; rac1 GTP-Binding Protein; Receptor, PAR-1; Signal Transduction; src-Family Kinases; Syntenins; Up-Regulation | 2015 |
A therapeutic trial of human melanomas with combined small interfering RNAs targeting adaptor molecules p130Cas and paxillin activated under expression of ganglioside GD3.
Topics: Animals; Cell Line, Tumor; Crk-Associated Substrate Protein; Gangliosides; Gene Expression Regulation, Neoplastic; Humans; Melanoma; Mice; Mice, Nude; Neoplasm Proteins; Paxillin; RNA, Small Interfering; Signal Transduction; Xenograft Model Antitumor Assays | 2016 |
Essential roles of integrin-mediated signaling for the enhancement of malignant properties of melanomas based on the expression of GD3.
Topics: Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Crk-Associated Substrate Protein; Extracellular Matrix; Focal Adhesions; Gangliosides; Humans; Integrin beta1; Melanoma; Neoplasm Invasiveness; Paxillin; Phosphorylation; Signal Transduction; Skin Neoplasms | 2008 |
Oncogenic NRAS has multiple effects on the malignant phenotype of human melanoma cells cultured in vitro.
Topics: Cell Adhesion Molecules; Cell Line, Tumor; Cyclin D1; Cyclins; Cytoskeleton; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Melanoma; Mutation; Oncogene Protein p21(ras); Paxillin; Phenotype; Phosphoproteins; Skin Neoplasms; Vinculin | 2009 |
Dynamic adhesions and MARCKS in melanoma cells.
Topics: Animals; Cell Adhesion; Cell Line, Tumor; Cell Movement; Humans; Integrin alpha3; Intercellular Junctions; Intracellular Signaling Peptides and Proteins; Isoenzymes; Melanoma; Melanoma, Experimental; Membrane Proteins; Mice; Myristoylated Alanine-Rich C Kinase Substrate; Paxillin; Protein Kinase C; Rats; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Vinculin | 2009 |
3,3',4,4',5,5'-hexahydroxystilbene impairs melanoma progression in a metastatic mouse model.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p21; Disease Models, Animal; Disease Progression; DNA Damage; Dose-Response Relationship, Drug; Female; Humans; Melanoma; Mice; Mice, SCID; Paxillin; Pyrogallol; Skin Neoplasms; Stilbenes; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2010 |
Ganglioside GD3 enhances adhesion signals and augments malignant properties of melanoma cells by recruiting integrins to glycolipid-enriched microdomains.
Topics: Cell Adhesion; Cell Line, Tumor; Collagen Type I; Collagen Type IV; Crk-Associated Substrate Protein; Extracellular Matrix; Focal Adhesion Kinase 1; Focal Adhesions; Gangliosides; Gene Expression Regulation, Neoplastic; Glycolipids; Humans; Integrin beta1; Melanoma; Membrane Microdomains; Paxillin; Phosphorylation; Signal Transduction | 2010 |
GM1 / GD1b / GA1 synthase expression results in the reduced cancer phenotypes with modulation of composition and raft-localization of gangliosides in a melanoma cell line.
Topics: Blotting, Western; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Chromatography, Thin Layer; Crk-Associated Substrate Protein; Flow Cytometry; Ganglioside Galactosyltransferase; Gangliosides; Humans; Intracellular Space; Melanoma; Membrane Microdomains; Paxillin; Phosphorylation; Transfection | 2010 |
Activity of BK(Ca) channel is modulated by membrane cholesterol content and association with Na+/K+-ATPase in human melanoma IGR39 cells.
Topics: Caveolins; Cell Line, Tumor; Cell Proliferation; Cholesterol; Humans; Ion Transport; Large-Conductance Calcium-Activated Potassium Channels; Melanoma; Membrane Microdomains; Membrane Potentials; Neoplasm Proteins; Paxillin; Sodium-Potassium-Exchanging ATPase | 2011 |
Focal adhesion disassembly is regulated by a RIAM to MEK-1 pathway.
Topics: Adaptor Proteins, Signal Transducing; Animals; Cell Line, Tumor; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Focal Adhesion Protein-Tyrosine Kinases; Focal Adhesions; Gene Knockdown Techniques; Humans; MAP Kinase Kinase 1; MAP Kinase Signaling System; Melanoma; Membrane Proteins; Mice; Models, Biological; Paxillin; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatase, Non-Receptor Type 12; rhoA GTP-Binding Protein; src-Family Kinases; Up-Regulation | 2012 |
The Na+ /H+ -exchanger (NHE1) generates pH nanodomains at focal adhesions.
Topics: Cation Transport Proteins; Cell Line, Tumor; Cell Movement; Fluoresceins; Fluorescent Dyes; Focal Adhesions; Guanidines; Humans; Hydrogen-Ion Concentration; Luminescent Proteins; Melanoma; Microscopy, Fluorescence; Neoplasm Invasiveness; Paxillin; Recombinant Fusion Proteins; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Sulfones; Transfection; Wheat Germ Agglutinins | 2013 |
HIV Nef, paxillin, and Pak1/2 regulate activation and secretion of TACE/ADAM10 proteases.
Topics: ADAM Proteins; ADAM10 Protein; ADAM17 Protein; Adaptor Proteins, Signal Transducing; Amino Acid Substitution; Amyloid Precursor Protein Secretases; Case-Control Studies; Enzyme Activation; HEK293 Cells; Heterogeneous-Nuclear Ribonucleoprotein K; HIV Infections; Humans; Melanoma; Membrane Microdomains; Membrane Proteins; Mutagenesis, Site-Directed; nef Gene Products, Human Immunodeficiency Virus; p21-Activated Kinases; Paxillin; Phosphorylation; Polycomb Repressive Complex 2; Protein Binding; Protein Kinase C-delta; Protein Precursors; Protein Processing, Post-Translational; Protein Transport; Ribonucleoproteins; Secretory Vesicles; Signal Transduction; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2013 |
Talin1 is critical for force-dependent reinforcement of initial integrin-cytoskeleton bonds but not tyrosine kinase activation.
Topics: Cell Adhesion; Cell Adhesion Molecules; Cell Line; Cell Line, Transformed; Contractile Proteins; Cytoskeletal Proteins; Cytoskeleton; Enzyme Activation; Fibronectins; Filamins; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Focal Adhesions; Humans; Integrins; Melanoma; Microfilament Proteins; Models, Biological; Paxillin; Phosphoproteins; Protein-Tyrosine Kinases; src-Family Kinases; Stress, Mechanical; Talin; Vinculin | 2003 |
Specific amino acid restriction inhibits attachment and spreading of human melanoma via modulation of the integrin/focal adhesion kinase pathway and actin cytoskeleton remodeling.
Topics: Amino Acids; Blotting, Western; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cytoskeletal Proteins; Cytoskeleton; Flow Cytometry; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Immunoprecipitation; Integrins; Melanoma; Microscopy, Confocal; Oncogene Protein pp60(v-src); Paxillin; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases | 2004 |
Ganglioside GD3 promotes cell growth and invasion through p130Cas and paxillin in malignant melanoma cells.
Topics: Cell Division; Cell Line, Tumor; Crk-Associated Substrate Protein; Cytoskeletal Proteins; Gangliosides; Humans; Melanoma; Neoplasm Invasiveness; Paxillin; Phenotype; Phosphoproteins; Phosphorylation; Proteins; Retinoblastoma-Like Protein p130; RNA, Small Interfering; Sialyltransferases; Transfection; Tyrosine | 2005 |
Overexpression of caveolin-1 in a human melanoma cell line results in dispersion of ganglioside GD3 from lipid rafts and alteration of leading edges, leading to attenuation of malignant properties.
Topics: Caveolin 1; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chromatography, Thin Layer; Crk-Associated Substrate Protein; Gangliosides; Humans; Mass Spectrometry; Melanoma; Membrane Microdomains; Mutation; Paxillin; Phosphorylation; Transfection | 2007 |
Focal adhesion kinase as well as p130Cas and paxillin is crucially involved in the enhanced malignant properties under expression of ganglioside GD3 in melanoma cells.
Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Cattle; Cell Line, Tumor; Cell Proliferation; Crk-Associated Substrate Protein; Focal Adhesion Protein-Tyrosine Kinases; Gangliosides; Humans; Immunoprecipitation; Mass Spectrometry; Melanoma; Molecular Sequence Data; Mutation; Neoplasm Invasiveness; Paxillin; Phosphorylation; Phosphotyrosine; Protein Binding; Serum; Transfection | 2008 |
Integrin alphavbeta3 mediates chemotactic and haptotactic motility in human melanoma cells through different signaling pathways.
Topics: Amino Acid Sequence; Antibodies; Cell Adhesion; Cell Line; Cell Movement; Chemotaxis; Cytoskeletal Proteins; Extracellular Matrix Proteins; GTP-Binding Proteins; Humans; Kinetics; Melanoma; Oligopeptides; Paxillin; Pertussis Toxin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Receptors, Vitronectin; Signal Transduction; Tumor Cells, Cultured; Virulence Factors, Bordetella; Vitronectin | 1996 |
The major myristoylated PKC substrate (MARCKS) is involved in cell spreading, tyrosine phosphorylation of paxillin, and focal contact formation.
Topics: Cell Adhesion; Cell Adhesion Molecules; Cell Size; Choroid Neoplasms; Cytoskeletal Proteins; Humans; Intracellular Signaling Peptides and Proteins; Melanoma; Membrane Proteins; Myristoylated Alanine-Rich C Kinase Substrate; Paxillin; Phosphoproteins; Phosphorylation; Proteins; Transfection; Tumor Cells, Cultured; Tyrosine; Vinculin | 1997 |
Cytostatin, an inhibitor of cell adhesion to extracellular matrix, selectively inhibits protein phosphatase 2A.
Topics: Animals; Antibiotics, Antineoplastic; Cell Adhesion; Cytoskeletal Proteins; Extracellular Matrix; Melanoma; Mice; Molecular Structure; Organophosphates; Paxillin; Phosphoprotein Phosphatases; Phosphoproteins; Protein Phosphatase 2; Pyrones; Tumor Cells, Cultured | 1999 |
Role of zyxin in differential cell spreading and proliferation of melanoma cells and melanocytes.
Topics: Cell Differentiation; Cell Division; Cells, Cultured; Cytoskeletal Proteins; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Glycoproteins; Humans; Melanocytes; Melanoma; Metalloproteins; Paxillin; Phenotype; Phosphoproteins; Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate; Zyxin | 2002 |