paxilline and Melanoma

Topics: Anoikis; Antibodies, Monoclonal; Carcinoma, Small Cell; Cell Line, Tumor; Cell Proliferation; Crk-Associated Substrate Protein; Focal Adhesion Protein-Tyrosine Kinases; Gangliosides; Glycosphingolipids; Humans; Lung Neoplasms; Melanoma; Neoplasm Invasiveness; Paxillin; Phosphorylation; Tyrosine

Topics: Cell Line, Tumor; Glycolipids; Humans; Keratan Sulfate; Melanoma; Melanoma, Cutaneous Malignant; Paxillin; Proteoglycans; Skin Neoplasms

Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Cell Line; Humans; Hydroxychloroquine; Integrin alphaVbeta3; Liposomes; Lung Neoplasms; Melanoma; Mice, Inbred C57BL; Neuropilin-1; Oligopeptides; Paclitaxel; Paxillin; Phosphatidylethanolamines; Polyethylene Glycols; Receptors, CXCR4

Topics: 3T3 Cells; Animals; Cell Line, Tumor; Cell Movement; CHO Cells; Cricetinae; Cricetulus; Focal Adhesions; Heterocyclic Compounds, 4 or More Rings; Humans; Integrin alpha4; Integrin alpha4beta1; Jurkat Cells; Melanoma; Mice; Mutant Proteins; Mutation; Myosin Type II; Neoplasm Invasiveness; Paxillin; Phenotype; Protein Binding; rac1 GTP-Binding Protein; rhoA GTP-Binding Protein; Signal Transduction; Stress Fibers

Topics: Adherens Junctions; Cell Line, Tumor; Cell Movement; Endothelial Cells; Focal Adhesion Kinase 1; Focal Adhesions; GTPase-Activating Proteins; Human Umbilical Vein Endothelial Cells; Humans; Melanoma; Mutation; Paxillin; Phosphorylation; Protein-Tyrosine Kinases; rhoA GTP-Binding Protein; Transendothelial and Transepithelial Migration

Topics: Animals; cdc42 GTP-Binding Protein; Cell Line, Tumor; Cell Movement; Factor VIIa; Factor X; Gene Expression Regulation, Neoplastic; Humans; JNK Mitogen-Activated Protein Kinases; Matrix Metalloproteinase 2; Melanoma; Mice; Neoplasm Metastasis; NF-kappa B; NIH 3T3 Cells; Paxillin; PDZ Domains; Protein Binding; rac1 GTP-Binding Protein; Receptor, PAR-1; Signal Transduction; src-Family Kinases; Syntenins; Up-Regulation

Topics: Animals; Cell Line, Tumor; Crk-Associated Substrate Protein; Gangliosides; Gene Expression Regulation, Neoplastic; Humans; Melanoma; Mice; Mice, Nude; Neoplasm Proteins; Paxillin; RNA, Small Interfering; Signal Transduction; Xenograft Model Antitumor Assays

Topics: Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Crk-Associated Substrate Protein; Extracellular Matrix; Focal Adhesions; Gangliosides; Humans; Integrin beta1; Melanoma; Neoplasm Invasiveness; Paxillin; Phosphorylation; Signal Transduction; Skin Neoplasms

Topics: Cell Adhesion Molecules; Cell Line, Tumor; Cyclin D1; Cyclins; Cytoskeleton; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Melanoma; Mutation; Oncogene Protein p21(ras); Paxillin; Phenotype; Phosphoproteins; Skin Neoplasms; Vinculin

Topics: Animals; Cell Adhesion; Cell Line, Tumor; Cell Movement; Humans; Integrin alpha3; Intercellular Junctions; Intracellular Signaling Peptides and Proteins; Isoenzymes; Melanoma; Melanoma, Experimental; Membrane Proteins; Mice; Myristoylated Alanine-Rich C Kinase Substrate; Paxillin; Protein Kinase C; Rats; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Vinculin

Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p21; Disease Models, Animal; Disease Progression; DNA Damage; Dose-Response Relationship, Drug; Female; Humans; Melanoma; Mice; Mice, SCID; Paxillin; Pyrogallol; Skin Neoplasms; Stilbenes; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays

Topics: Cell Adhesion; Cell Line, Tumor; Collagen Type I; Collagen Type IV; Crk-Associated Substrate Protein; Extracellular Matrix; Focal Adhesion Kinase 1; Focal Adhesions; Gangliosides; Gene Expression Regulation, Neoplastic; Glycolipids; Humans; Integrin beta1; Melanoma; Membrane Microdomains; Paxillin; Phosphorylation; Signal Transduction

Topics: Blotting, Western; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Chromatography, Thin Layer; Crk-Associated Substrate Protein; Flow Cytometry; Ganglioside Galactosyltransferase; Gangliosides; Humans; Intracellular Space; Melanoma; Membrane Microdomains; Paxillin; Phosphorylation; Transfection

Topics: Caveolins; Cell Line, Tumor; Cell Proliferation; Cholesterol; Humans; Ion Transport; Large-Conductance Calcium-Activated Potassium Channels; Melanoma; Membrane Microdomains; Membrane Potentials; Neoplasm Proteins; Paxillin; Sodium-Potassium-Exchanging ATPase

Topics: Adaptor Proteins, Signal Transducing; Animals; Cell Line, Tumor; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Focal Adhesion Protein-Tyrosine Kinases; Focal Adhesions; Gene Knockdown Techniques; Humans; MAP Kinase Kinase 1; MAP Kinase Signaling System; Melanoma; Membrane Proteins; Mice; Models, Biological; Paxillin; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatase, Non-Receptor Type 12; rhoA GTP-Binding Protein; src-Family Kinases; Up-Regulation

Topics: Cation Transport Proteins; Cell Line, Tumor; Cell Movement; Fluoresceins; Fluorescent Dyes; Focal Adhesions; Guanidines; Humans; Hydrogen-Ion Concentration; Luminescent Proteins; Melanoma; Microscopy, Fluorescence; Neoplasm Invasiveness; Paxillin; Recombinant Fusion Proteins; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Sulfones; Transfection; Wheat Germ Agglutinins

Topics: ADAM Proteins; ADAM10 Protein; ADAM17 Protein; Adaptor Proteins, Signal Transducing; Amino Acid Substitution; Amyloid Precursor Protein Secretases; Case-Control Studies; Enzyme Activation; HEK293 Cells; Heterogeneous-Nuclear Ribonucleoprotein K; HIV Infections; Humans; Melanoma; Membrane Microdomains; Membrane Proteins; Mutagenesis, Site-Directed; nef Gene Products, Human Immunodeficiency Virus; p21-Activated Kinases; Paxillin; Phosphorylation; Polycomb Repressive Complex 2; Protein Binding; Protein Kinase C-delta; Protein Precursors; Protein Processing, Post-Translational; Protein Transport; Ribonucleoproteins; Secretory Vesicles; Signal Transduction; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

Topics: Cell Adhesion; Cell Adhesion Molecules; Cell Line; Cell Line, Transformed; Contractile Proteins; Cytoskeletal Proteins; Cytoskeleton; Enzyme Activation; Fibronectins; Filamins; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Focal Adhesions; Humans; Integrins; Melanoma; Microfilament Proteins; Models, Biological; Paxillin; Phosphoproteins; Protein-Tyrosine Kinases; src-Family Kinases; Stress, Mechanical; Talin; Vinculin

Topics: Amino Acids; Blotting, Western; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cytoskeletal Proteins; Cytoskeleton; Flow Cytometry; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Immunoprecipitation; Integrins; Melanoma; Microscopy, Confocal; Oncogene Protein pp60(v-src); Paxillin; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases

Topics: Cell Division; Cell Line, Tumor; Crk-Associated Substrate Protein; Cytoskeletal Proteins; Gangliosides; Humans; Melanoma; Neoplasm Invasiveness; Paxillin; Phenotype; Phosphoproteins; Phosphorylation; Proteins; Retinoblastoma-Like Protein p130; RNA, Small Interfering; Sialyltransferases; Transfection; Tyrosine

Topics: Caveolin 1; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chromatography, Thin Layer; Crk-Associated Substrate Protein; Gangliosides; Humans; Mass Spectrometry; Melanoma; Membrane Microdomains; Mutation; Paxillin; Phosphorylation; Transfection

Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Cattle; Cell Line, Tumor; Cell Proliferation; Crk-Associated Substrate Protein; Focal Adhesion Protein-Tyrosine Kinases; Gangliosides; Humans; Immunoprecipitation; Mass Spectrometry; Melanoma; Molecular Sequence Data; Mutation; Neoplasm Invasiveness; Paxillin; Phosphorylation; Phosphotyrosine; Protein Binding; Serum; Transfection

Topics: Amino Acid Sequence; Antibodies; Cell Adhesion; Cell Line; Cell Movement; Chemotaxis; Cytoskeletal Proteins; Extracellular Matrix Proteins; GTP-Binding Proteins; Humans; Kinetics; Melanoma; Oligopeptides; Paxillin; Pertussis Toxin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Receptors, Vitronectin; Signal Transduction; Tumor Cells, Cultured; Virulence Factors, Bordetella; Vitronectin

Topics: Cell Adhesion; Cell Adhesion Molecules; Cell Size; Choroid Neoplasms; Cytoskeletal Proteins; Humans; Intracellular Signaling Peptides and Proteins; Melanoma; Membrane Proteins; Myristoylated Alanine-Rich C Kinase Substrate; Paxillin; Phosphoproteins; Phosphorylation; Proteins; Transfection; Tumor Cells, Cultured; Tyrosine; Vinculin

Topics: Animals; Antibiotics, Antineoplastic; Cell Adhesion; Cytoskeletal Proteins; Extracellular Matrix; Melanoma; Mice; Molecular Structure; Organophosphates; Paxillin; Phosphoprotein Phosphatases; Phosphoproteins; Protein Phosphatase 2; Pyrones; Tumor Cells, Cultured

Topics: Cell Differentiation; Cell Division; Cells, Cultured; Cytoskeletal Proteins; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Glycoproteins; Humans; Melanocytes; Melanoma; Metalloproteins; Paxillin; Phenotype; Phosphoproteins; Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate; Zyxin