Page last updated: 2024-08-26

paxilline and Melanoma

paxilline has been researched along with Melanoma in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (11.54)18.2507
2000's10 (38.46)29.6817
2010's12 (46.15)24.3611
2020's1 (3.85)2.80

Authors

AuthorsStudies
Harada, Y; Isei, T; Kanto, N; Maeda, K; Ohe, S; Ohkawa, Y; Tachibana, K; Taniguchi, N1
He, Q; Li, M; Liu, J; Rao, J; Tang, X; Wan, D; Wang, X; Wang, Y; Wei, J; Xia, C; Yin, S; Zhang, Z1
Chen, SH; Hung, WC; Konstantopoulos, K; Lo, YC; Paul, CD; Stroka, KM; Yang, JT1
Bai, H; Chen, F; Dong, C; Fu, C; Song, E; Song, Y; Wu, C; Ye, Q; Zeng, P; Zhang, P1
Aissaoui, H; Bordet, JC; Boucharaba, A; Boukerche, H; Négrier, C; Prévost, C; Sanhadji, K1
Bhuiyan, RH; Furukawa, K; Hamamura, K; Makino, Y; Nakashima, H; Ohkawa, Y; Ohmi, Y; Takei, Y1
Furukawa, K; Hamamura, K; Miyata, M; Miyazaki, S; Ohkawa, Y1
Clark, E; Eskandarpour, M; Hansson, J; Huang, F; Reeves, KA1
Estrada-Bernal, A; Gatlin, JC; Pfenninger, KH; Sunpaweravong, S1
Elbling, L; Fiebiger, E; Gerner, C; Jäger, W; Kunstfeld, R; Mikula, M; Paulitschke, V; Pehamberger, H; Riemer, AB; Scheiner, O; Schicher, N; Swoboda, A; Szekeres, T; Trimurtulu, G; Venkateswarlu, S1
Furukawa, K; Hamamura, K; Kambe, M; Miyata, M; Miyazaki, S; Ohkawa, Y; Ohmi, Y; Tajima, O; Yamauchi, Y1
Dong, Y; Furukawa, K; Hamamura, K; Ikeda, K; Kondo, Y; Matsumoto, Y; Ohmi, Y; Taguchi, R; Yamauchi, Y; Zhang, Q1
Itokazu, Y; Käkelä, R; Korpi, ER; Somerharju, P; Tajima, N1
Arellano-Sánchez, N; Bartolomé, RA; Coló, GP; Hernández-Varas, P; Lock, J; Strömblad, S; Teixidó, J1
Ludwig, FT; Schwab, A; Stock, C1
Baur, AS; Bräu, T; Dindorf, J; Dreyer, FS; Federico, M; Gross, S; Harrer, T; Johnston, IC; Krätzel, K; Kremmer, E; Lee, JH; Lichtenheld, M; Saksela, K; Schlötzer-Schrehardt, U; Schuler, G; Wittki, S; Zeidler, R1
Critchley, DR; Giannone, G; Jiang, G; Sheetz, MP; Sutton, DH1
Ding, M; Fu, X; Fu, YM; Li, YQ; Meadows, GG; Yu, ZX; Zhang, H1
Furukawa, K; Hamamura, K; Hattori, H; Hattori, T; Hayashi, T; Lloyd, KO; Mizutani, H; Nakano, J; Nakashima, H; Okuda, T; Ueda, M; Urano, T1
Aixinjueluo, W; Furukawa, K; Hamamura, K1
Furukawa, K; Hamamura, K; Houjou, T; Mitsudo, K; Nakashima, H; Taguchi, R; Tohnai, I; Ueda, M; Urano, T; Yamamoto, N1
Furukawa, K; Hamamura, K; Miyazaki, S; Nakashima, H; Ohkawa, Y; Tsuji, M; Ueda, M; Urano, T; Yamamoto, N1
Aznavoorian, S; Liotta, LA; McClanahan, J; Parsons, J; Stracke, ML1
Darbon, JM; Malecaze, F; Manenti, S1
Amemiya, M; Ishizuka, M; Kawada, M; Takeuchi, T1
Amodeo, DM; Byers, HR; Dekker, SK; Jalbert, NL; Leccia, MT; van der Gaag, EJ1

Reviews

1 review(s) available for paxilline and Melanoma

ArticleYear
Biosignals modulated by tumor-associated carbohydrate antigens: novel targets for cancer therapy.
    Annals of the New York Academy of Sciences, 2006, Volume: 1086

    Topics: Anoikis; Antibodies, Monoclonal; Carcinoma, Small Cell; Cell Line, Tumor; Cell Proliferation; Crk-Associated Substrate Protein; Focal Adhesion Protein-Tyrosine Kinases; Gangliosides; Glycosphingolipids; Humans; Lung Neoplasms; Melanoma; Neoplasm Invasiveness; Paxillin; Phosphorylation; Tyrosine

2006

Other Studies

25 other study(ies) available for paxilline and Melanoma

ArticleYear
The expression of keratan sulfate in malignant melanoma enhances the adhesion and invasion activity of melanoma cells.
    The Journal of dermatology, 2022, Volume: 49, Issue:10

    Topics: Cell Line, Tumor; Glycolipids; Humans; Keratan Sulfate; Melanoma; Melanoma, Cutaneous Malignant; Paxillin; Proteoglycans; Skin Neoplasms

2022
Dual receptor recognizing liposomes containing paclitaxel and hydroxychloroquine for primary and metastatic melanoma treatment via autophagy-dependent and independent pathways.
    Journal of controlled release : official journal of the Controlled Release Society, 2018, 10-28, Volume: 288

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Cell Line; Humans; Hydroxychloroquine; Integrin alphaVbeta3; Liposomes; Lung Neoplasms; Melanoma; Mice, Inbred C57BL; Neuropilin-1; Oligopeptides; Paclitaxel; Paxillin; Phosphatidylethanolamines; Polyethylene Glycols; Receptors, CXCR4

2018
Distinct signaling mechanisms regulate migration in unconfined versus confined spaces.
    The Journal of cell biology, 2013, Sep-02, Volume: 202, Issue:5

    Topics: 3T3 Cells; Animals; Cell Line, Tumor; Cell Movement; CHO Cells; Cricetinae; Cricetulus; Focal Adhesions; Heterocyclic Compounds, 4 or More Rings; Humans; Integrin alpha4; Integrin alpha4beta1; Jurkat Cells; Melanoma; Mice; Mutant Proteins; Mutation; Myosin Type II; Neoplasm Invasiveness; Paxillin; Phenotype; Protein Binding; rac1 GTP-Binding Protein; rhoA GTP-Binding Protein; Signal Transduction; Stress Fibers

2013
RacGAP1-driven focal adhesion formation promotes melanoma transendothelial migration through mediating adherens junction disassembly.
    Biochemical and biophysical research communications, 2015, Mar-27, Volume: 459, Issue:1

    Topics: Adherens Junctions; Cell Line, Tumor; Cell Movement; Endothelial Cells; Focal Adhesion Kinase 1; Focal Adhesions; GTPase-Activating Proteins; Human Umbilical Vein Endothelial Cells; Humans; Melanoma; Mutation; Paxillin; Phosphorylation; Protein-Tyrosine Kinases; rhoA GTP-Binding Protein; Transendothelial and Transepithelial Migration

2015
MDA-9/syntenin is essential for factor VIIa-induced signaling, migration, and metastasis in melanoma cells.
    The Journal of biological chemistry, 2015, Feb-06, Volume: 290, Issue:6

    Topics: Animals; cdc42 GTP-Binding Protein; Cell Line, Tumor; Cell Movement; Factor VIIa; Factor X; Gene Expression Regulation, Neoplastic; Humans; JNK Mitogen-Activated Protein Kinases; Matrix Metalloproteinase 2; Melanoma; Mice; Neoplasm Metastasis; NF-kappa B; NIH 3T3 Cells; Paxillin; PDZ Domains; Protein Binding; rac1 GTP-Binding Protein; Receptor, PAR-1; Signal Transduction; src-Family Kinases; Syntenins; Up-Regulation

2015
A therapeutic trial of human melanomas with combined small interfering RNAs targeting adaptor molecules p130Cas and paxillin activated under expression of ganglioside GD3.
    Biochimica et biophysica acta, 2016, Volume: 1860, Issue:8

    Topics: Animals; Cell Line, Tumor; Crk-Associated Substrate Protein; Gangliosides; Gene Expression Regulation, Neoplastic; Humans; Melanoma; Mice; Mice, Nude; Neoplasm Proteins; Paxillin; RNA, Small Interfering; Signal Transduction; Xenograft Model Antitumor Assays

2016
Essential roles of integrin-mediated signaling for the enhancement of malignant properties of melanomas based on the expression of GD3.
    Biochemical and biophysical research communications, 2008, Aug-15, Volume: 373, Issue:1

    Topics: Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Crk-Associated Substrate Protein; Extracellular Matrix; Focal Adhesions; Gangliosides; Humans; Integrin beta1; Melanoma; Neoplasm Invasiveness; Paxillin; Phosphorylation; Signal Transduction; Skin Neoplasms

2008
Oncogenic NRAS has multiple effects on the malignant phenotype of human melanoma cells cultured in vitro.
    International journal of cancer, 2009, Jan-01, Volume: 124, Issue:1

    Topics: Cell Adhesion Molecules; Cell Line, Tumor; Cyclin D1; Cyclins; Cytoskeleton; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Melanoma; Mutation; Oncogene Protein p21(ras); Paxillin; Phenotype; Phosphoproteins; Skin Neoplasms; Vinculin

2009
Dynamic adhesions and MARCKS in melanoma cells.
    Journal of cell science, 2009, Jul-01, Volume: 122, Issue:Pt 13

    Topics: Animals; Cell Adhesion; Cell Line, Tumor; Cell Movement; Humans; Integrin alpha3; Intercellular Junctions; Intracellular Signaling Peptides and Proteins; Isoenzymes; Melanoma; Melanoma, Experimental; Membrane Proteins; Mice; Myristoylated Alanine-Rich C Kinase Substrate; Paxillin; Protein Kinase C; Rats; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Vinculin

2009
3,3',4,4',5,5'-hexahydroxystilbene impairs melanoma progression in a metastatic mouse model.
    The Journal of investigative dermatology, 2010, Volume: 130, Issue:6

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p21; Disease Models, Animal; Disease Progression; DNA Damage; Dose-Response Relationship, Drug; Female; Humans; Melanoma; Mice; Mice, SCID; Paxillin; Pyrogallol; Skin Neoplasms; Stilbenes; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays

2010
Ganglioside GD3 enhances adhesion signals and augments malignant properties of melanoma cells by recruiting integrins to glycolipid-enriched microdomains.
    The Journal of biological chemistry, 2010, Aug-27, Volume: 285, Issue:35

    Topics: Cell Adhesion; Cell Line, Tumor; Collagen Type I; Collagen Type IV; Crk-Associated Substrate Protein; Extracellular Matrix; Focal Adhesion Kinase 1; Focal Adhesions; Gangliosides; Gene Expression Regulation, Neoplastic; Glycolipids; Humans; Integrin beta1; Melanoma; Membrane Microdomains; Paxillin; Phosphorylation; Signal Transduction

2010
GM1 / GD1b / GA1 synthase expression results in the reduced cancer phenotypes with modulation of composition and raft-localization of gangliosides in a melanoma cell line.
    Cancer science, 2010, Volume: 101, Issue:9

    Topics: Blotting, Western; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Chromatography, Thin Layer; Crk-Associated Substrate Protein; Flow Cytometry; Ganglioside Galactosyltransferase; Gangliosides; Humans; Intracellular Space; Melanoma; Membrane Microdomains; Paxillin; Phosphorylation; Transfection

2010
Activity of BK(Ca) channel is modulated by membrane cholesterol content and association with Na+/K+-ATPase in human melanoma IGR39 cells.
    The Journal of biological chemistry, 2011, Feb-18, Volume: 286, Issue:7

    Topics: Caveolins; Cell Line, Tumor; Cell Proliferation; Cholesterol; Humans; Ion Transport; Large-Conductance Calcium-Activated Potassium Channels; Melanoma; Membrane Microdomains; Membrane Potentials; Neoplasm Proteins; Paxillin; Sodium-Potassium-Exchanging ATPase

2011
Focal adhesion disassembly is regulated by a RIAM to MEK-1 pathway.
    Journal of cell science, 2012, Nov-15, Volume: 125, Issue:Pt 22

    Topics: Adaptor Proteins, Signal Transducing; Animals; Cell Line, Tumor; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Focal Adhesion Protein-Tyrosine Kinases; Focal Adhesions; Gene Knockdown Techniques; Humans; MAP Kinase Kinase 1; MAP Kinase Signaling System; Melanoma; Membrane Proteins; Mice; Models, Biological; Paxillin; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatase, Non-Receptor Type 12; rhoA GTP-Binding Protein; src-Family Kinases; Up-Regulation

2012
The Na+ /H+ -exchanger (NHE1) generates pH nanodomains at focal adhesions.
    Journal of cellular physiology, 2013, Volume: 228, Issue:6

    Topics: Cation Transport Proteins; Cell Line, Tumor; Cell Movement; Fluoresceins; Fluorescent Dyes; Focal Adhesions; Guanidines; Humans; Hydrogen-Ion Concentration; Luminescent Proteins; Melanoma; Microscopy, Fluorescence; Neoplasm Invasiveness; Paxillin; Recombinant Fusion Proteins; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchangers; Sulfones; Transfection; Wheat Germ Agglutinins

2013
HIV Nef, paxillin, and Pak1/2 regulate activation and secretion of TACE/ADAM10 proteases.
    Molecular cell, 2013, Feb-21, Volume: 49, Issue:4

    Topics: ADAM Proteins; ADAM10 Protein; ADAM17 Protein; Adaptor Proteins, Signal Transducing; Amino Acid Substitution; Amyloid Precursor Protein Secretases; Case-Control Studies; Enzyme Activation; HEK293 Cells; Heterogeneous-Nuclear Ribonucleoprotein K; HIV Infections; Humans; Melanoma; Membrane Microdomains; Membrane Proteins; Mutagenesis, Site-Directed; nef Gene Products, Human Immunodeficiency Virus; p21-Activated Kinases; Paxillin; Phosphorylation; Polycomb Repressive Complex 2; Protein Binding; Protein Kinase C-delta; Protein Precursors; Protein Processing, Post-Translational; Protein Transport; Ribonucleoproteins; Secretory Vesicles; Signal Transduction; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

2013
Talin1 is critical for force-dependent reinforcement of initial integrin-cytoskeleton bonds but not tyrosine kinase activation.
    The Journal of cell biology, 2003, Oct-27, Volume: 163, Issue:2

    Topics: Cell Adhesion; Cell Adhesion Molecules; Cell Line; Cell Line, Transformed; Contractile Proteins; Cytoskeletal Proteins; Cytoskeleton; Enzyme Activation; Fibronectins; Filamins; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Focal Adhesions; Humans; Integrins; Melanoma; Microfilament Proteins; Models, Biological; Paxillin; Phosphoproteins; Protein-Tyrosine Kinases; src-Family Kinases; Stress, Mechanical; Talin; Vinculin

2003
Specific amino acid restriction inhibits attachment and spreading of human melanoma via modulation of the integrin/focal adhesion kinase pathway and actin cytoskeleton remodeling.
    Clinical & experimental metastasis, 2004, Volume: 21, Issue:7

    Topics: Amino Acids; Blotting, Western; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cytoskeletal Proteins; Cytoskeleton; Flow Cytometry; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Immunoprecipitation; Integrins; Melanoma; Microscopy, Confocal; Oncogene Protein pp60(v-src); Paxillin; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases

2004
Ganglioside GD3 promotes cell growth and invasion through p130Cas and paxillin in malignant melanoma cells.
    Proceedings of the National Academy of Sciences of the United States of America, 2005, Aug-02, Volume: 102, Issue:31

    Topics: Cell Division; Cell Line, Tumor; Crk-Associated Substrate Protein; Cytoskeletal Proteins; Gangliosides; Humans; Melanoma; Neoplasm Invasiveness; Paxillin; Phenotype; Phosphoproteins; Phosphorylation; Proteins; Retinoblastoma-Like Protein p130; RNA, Small Interfering; Sialyltransferases; Transfection; Tyrosine

2005
Overexpression of caveolin-1 in a human melanoma cell line results in dispersion of ganglioside GD3 from lipid rafts and alteration of leading edges, leading to attenuation of malignant properties.
    Cancer science, 2007, Volume: 98, Issue:4

    Topics: Caveolin 1; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chromatography, Thin Layer; Crk-Associated Substrate Protein; Gangliosides; Humans; Mass Spectrometry; Melanoma; Membrane Microdomains; Mutation; Paxillin; Phosphorylation; Transfection

2007
Focal adhesion kinase as well as p130Cas and paxillin is crucially involved in the enhanced malignant properties under expression of ganglioside GD3 in melanoma cells.
    Biochimica et biophysica acta, 2008, Volume: 1780, Issue:3

    Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Cattle; Cell Line, Tumor; Cell Proliferation; Crk-Associated Substrate Protein; Focal Adhesion Protein-Tyrosine Kinases; Gangliosides; Humans; Immunoprecipitation; Mass Spectrometry; Melanoma; Molecular Sequence Data; Mutation; Neoplasm Invasiveness; Paxillin; Phosphorylation; Phosphotyrosine; Protein Binding; Serum; Transfection

2008
Integrin alphavbeta3 mediates chemotactic and haptotactic motility in human melanoma cells through different signaling pathways.
    The Journal of biological chemistry, 1996, Feb-09, Volume: 271, Issue:6

    Topics: Amino Acid Sequence; Antibodies; Cell Adhesion; Cell Line; Cell Movement; Chemotaxis; Cytoskeletal Proteins; Extracellular Matrix Proteins; GTP-Binding Proteins; Humans; Kinetics; Melanoma; Oligopeptides; Paxillin; Pertussis Toxin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Receptors, Vitronectin; Signal Transduction; Tumor Cells, Cultured; Virulence Factors, Bordetella; Vitronectin

1996
The major myristoylated PKC substrate (MARCKS) is involved in cell spreading, tyrosine phosphorylation of paxillin, and focal contact formation.
    FEBS letters, 1997, Dec-08, Volume: 419, Issue:1

    Topics: Cell Adhesion; Cell Adhesion Molecules; Cell Size; Choroid Neoplasms; Cytoskeletal Proteins; Humans; Intracellular Signaling Peptides and Proteins; Melanoma; Membrane Proteins; Myristoylated Alanine-Rich C Kinase Substrate; Paxillin; Phosphoproteins; Phosphorylation; Proteins; Transfection; Tumor Cells, Cultured; Tyrosine; Vinculin

1997
Cytostatin, an inhibitor of cell adhesion to extracellular matrix, selectively inhibits protein phosphatase 2A.
    Biochimica et biophysica acta, 1999, Nov-11, Volume: 1452, Issue:2

    Topics: Animals; Antibiotics, Antineoplastic; Cell Adhesion; Cytoskeletal Proteins; Extracellular Matrix; Melanoma; Mice; Molecular Structure; Organophosphates; Paxillin; Phosphoprotein Phosphatases; Phosphoproteins; Protein Phosphatase 2; Pyrones; Tumor Cells, Cultured

1999
Role of zyxin in differential cell spreading and proliferation of melanoma cells and melanocytes.
    The Journal of investigative dermatology, 2002, Volume: 118, Issue:2

    Topics: Cell Differentiation; Cell Division; Cells, Cultured; Cytoskeletal Proteins; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Glycoproteins; Humans; Melanocytes; Melanoma; Metalloproteins; Paxillin; Phenotype; Phosphoproteins; Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate; Zyxin

2002