Page last updated: 2024-08-26

paxilline and Lung Neoplasms

paxilline has been researched along with Lung Neoplasms in 45 studies

Research

Studies (45)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (2.22)	18.2507
2000's	15 (33.33)	29.6817
2010's	25 (55.56)	24.3611
2020's	4 (8.89)	2.80

Authors

Authors	Studies
Chen, H; He, P; Lin, G; Lin, Z; Liu, C; Liu, G; Lu, Z; Mu, D; Shi, Y; Zhang, Y; Zheng, H	1
Gan, L; Han, D; Liu, S; Lu, S; Lu, T; Qin, W; Wen, W; Wu, X; Xu, C; Yang, F; Zhang, J; Zhang, K	1
Awanis, G; Banerjee, S; Elmeligy, A; Gavrilovic, J; Johnson, R; Raveenthiraraj, S; Sobolewski, A; Warren, D	1
Chang, Y; Ding, X; Li, M; Li, Y; Liu, B; Shen, H; Wang, Y; Xie, SM; Xing, L	1
He, Q; Li, M; Liu, J; Rao, J; Tang, X; Wan, D; Wang, X; Wang, Y; Wei, J; Xia, C; Yin, S; Zhang, Z	1
Chen, G; Jiang, WG; Li, S; Ye, L; Yu, H; Zhao, H	1
De Rycker, M; Hibbert, A; Kermorgant, S; Lachmann, S; Milanovic, M; Parker, PJ; Radtke, S; Rossé, C	1
Chen, XP; Dang, YY; Lu, JJ; Wang, YT; Xu, WS	1
Mu, W; Yue, S; Zöller, M	1
Arif, Q; Bindokas, VP; Brand, TM; Carey, G; Ferguson, MK; Hasina, R; Hseu, RD; Husain, AN; Iida, M; Kawada, I; Krishnaswamy, S; Lennon, FE; Natarajan, V; Robinson, M; Salgia, R; Singleton, PA; Tan, YH; Tretiakova, M; Usatyuk, P; Vokes, EE; Wheeler, DL	1
Díaz, J; Leyton, L; Mendoza, P; Ortiz, R; Quest, AF; Stupack, D; Torres, VA	1
Hwan Kim, S; Kim, J	1
Chen, CY; Chen, YC; Cheng, YW; Lee, H; Lee, MC; Wu, DW; Wu, JY; Wu, TC	1
Bi, H; Bi, Y; Gao, F; Han, Y; Wang, X	1
Chan, SH; Chang, JW; Cheng, AJ; Chiang, SL; Chiang, WF; Huang, WC; Jang, TH; Juang, JL; Ko, YC; Liao, CT; Lu, YC; Shieh, TY; Wang, HC; Wang, LH; Yen, TC	1
Li, Y; Liu, BL; Liu, DZ; Wang, F; Wang, W; Xu, H; Zhang, LY	1
Bianco, C; Bianco, R; Ciardiello, F; Cipolletta, A; D'Amato, C; D'Amato, V; De Placido, S; Di Mauro, C; Formisano, L; Fulciniti, F; Marciano, R; Nappi, L; Raimondo, L; Rosa, R; Servetto, A; Veneziani, BM	1
Huang, CC; Lee, H; Lin, PL; Wu, DW	1
Chen, CY; Chu, CL; Lee, H; Wu, DW	1
Choi, WJ; Jung, J; Kim, J; Kim, SH; Lee, JO; Moon, SH; Park, JK	1
Blons, H; Cazes, A; Houllier, AM; Laurent-Puig, P; Le Corre, D; Pallier, K	1
Haga, H; Ishihara, S; Kawaguchi, H; Nakamura, H; Nishioka, T; Ohba, Y; Shirato, H; Tsuda, M; Tsutsumi, K; Yamazaki, R; Yasuda, M; Yazawa, N	1
Ferguson, MK; Kanteti, R; Salgia, R; Yala, S	1
Cagle, PT; Husain, AN; Li, M; Salgia, R; Song, J; Tretiakova, M	1
Henderson, L; Husain, AN; Joseph, L; Krausz, T; Mackinnon, AC; Mehta, RG; Reid, ME; Salgia, R; Tretiakova, M; Yan, BC	1
Deakin, NO; Turner, CE	1
Chen, CY; Cheng, YW; Lee, H; Wang, J; Wu, DW	1
Balraj, G; Chang, TT; Chen, JY; Cheng, HC; Huang, SM; Juan, HF; Li, WS; Sun, YC; Tang, YA; Wang, SC; Wang, YC; Wu, KW; Wu, LW	1
Azzalis, LA; de Abreu, LC; Feder, D; Fonseca, FL; Junqueira, VB; Nogoceke, E; Valenti, VE	1
Callison, C; Chen, H; Gonzalez, AL; Massion, PP; Ocak, S	1
Chen, MY; Hsu, PC; Huang, SM; Li, WS; Lu, KT; More, SV; Wang, YC	1
Frame, MC; Lahlou, H; Muller, WJ; Sanguin-Gendreau, V	1
Li, H; Zuo, W	1
Fox, EA; Griffin, JD; Johnson, BE; Kijima, T; Ma, PC; Maulik, G; Salgia, R; Sattler, M	1
Beinke, C; Cordes, N; Van Beuningen, D	1
Cordes, N	1
Brábek, J; Constancio, SS; Hanks, SK; Pozzi, A; Shin, NY; Siesser, PF	1
Donato, NJ; Johnson, FM; Saigal, B; Talpaz, M	1
Aixinjueluo, W; Furukawa, K; Hamamura, K	1
Han, IO; Hwang, JS; Hwang, SY; Jung, JW; Oh, ES; Park, S	1
Anderson, GM; Chen, Q; Doshi, P; Ferrante, C; Manning, CD; McCabe, FL; Millar, H; Nakada, MT; Shahied-Arruda, L; Sharp, C	1
Ahmed, S; Bindokas, VP; Bueno, R; Faoro, L; Ferguson, MK; Girard, L; Gordon, GJ; Husain, AN; Jagadeeswaran, R; Janamanchi, V; Kanteti, R; Krausz, T; Krishnaswamy, S; Lingen, MW; Loganathan, S; Mackinnon, AC; Minna, J; Nallasura, V; Natarajan, V; Reichman, T; Salgia, R; Sattler, M; Schwartz, S; Seiwert, TY; Soulii, L; Sugarbaker, D; Surawska, H; Szeto, LL; Tretiakova, MS; Vigneswaran, W; Vokes, EE; Wang, YC; Zumba, O	1
Clack, G; Dixon, JM; Elvin, P; Fennell, M; Green, TP; Jacobs, V; Jones, RJ; Marshall, A; Renshaw, L; Womack, C; Young, O	1
Chen, LB; Chen, WC; Ewaniuk, DS; Griffin, JD; Li, JL; Pisick, E; Richards, W; Rollins, BJ; Salgia, R; Sattler, M; Shapiro, GI; Sugarbaker, DJ; Wang, YB	1
Garcia-Marin, LJ; Jensen, RT; Leyton, J; Moody, TW; Tapia, JA	1

Reviews

1 review(s) available for paxilline and Lung Neoplasms

Article	Year
Biosignals modulated by tumor-associated carbohydrate antigens: novel targets for cancer therapy. Annals of the New York Academy of Sciences, 2006, Volume: 1086 Topics: Anoikis; Antibodies, Monoclonal; Carcinoma, Small Cell; Cell Line, Tumor; Cell Proliferation; Crk-Associated Substrate Protein; Focal Adhesion Protein-Tyrosine Kinases; Gangliosides; Glycosphingolipids; Humans; Lung Neoplasms; Melanoma; Neoplasm Invasiveness; Paxillin; Phosphorylation; Tyrosine	2006

Article

Year

Biosignals modulated by tumor-associated carbohydrate antigens: novel targets for cancer therapy.

Annals of the New York Academy of Sciences, 2006, Volume: 1086

Topics: Anoikis; Antibodies, Monoclonal; Carcinoma, Small Cell; Cell Line, Tumor; Cell Proliferation; Crk-Associated Substrate Protein; Focal Adhesion Protein-Tyrosine Kinases; Gangliosides; Glycosphingolipids; Humans; Lung Neoplasms; Melanoma; Neoplasm Invasiveness; Paxillin; Phosphorylation; Tyrosine

2006

Other Studies

44 other study(ies) available for paxilline and Lung Neoplasms

Article	Year
Biomimetic nanoparticles blocking autophagy for enhanced chemotherapy and metastasis inhibition via reversing focal adhesion disassembly. Journal of nanobiotechnology, 2021, Dec-24, Volume: 19, Issue:1 Topics: Animals; Antineoplastic Agents; Autophagy; Biomimetic Materials; Cadherins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Carriers; Drug Liberation; Focal Adhesions; Humans; Hydroxychloroquine; Lung Neoplasms; Mice; Nanoparticles; Neoplasms; Oxaliplatin; Paxillin; Polylactic Acid-Polyglycolic Acid Copolymer	2021
CD248 promotes migration and metastasis of osteosarcoma through ITGB1-mediated FAK-paxillin pathway activation. BMC cancer, 2023, Mar-30, Volume: 23, Issue:1 Topics: Animals; Antigens, CD; Antigens, Neoplasm; Bone Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Gene Expression Regulation, Neoplastic; Integrin beta1; Lung Neoplasms; Mice; Mice, Nude; Osteosarcoma; Paxillin	2023
HGF/c-Met/β1-integrin signalling axis induces tunneling nanotubes in A549 lung adenocarcinoma cells. Life science alliance, 2023, Volume: 6, Issue:10 Topics: Adenocarcinoma of Lung; Carcinoma, Non-Small-Cell Lung; Hepatocyte Growth Factor; Humans; Integrins; Lung Neoplasms; Paxillin; Phosphatidylinositol 3-Kinases	2023
ETV4 overexpression promotes progression of non-small cell lung cancer by upregulating PXN and MMP1 transcriptionally. Molecular carcinogenesis, 2020, Volume: 59, Issue:1 Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Matrix Metalloproteinase 1; Mice, Inbred BALB C; Mice, Nude; Paxillin; Proto-Oncogene Proteins c-ets; Transcriptional Activation	2020
Dual receptor recognizing liposomes containing paclitaxel and hydroxychloroquine for primary and metastatic melanoma treatment via autophagy-dependent and independent pathways. Journal of controlled release : official journal of the Controlled Release Society, 2018, 10-28, Volume: 288 Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Cell Line; Humans; Hydroxychloroquine; Integrin alphaVbeta3; Liposomes; Lung Neoplasms; Melanoma; Mice, Inbred C57BL; Neuropilin-1; Oligopeptides; Paclitaxel; Paxillin; Phosphatidylethanolamines; Polyethylene Glycols; Receptors, CXCR4	2018
DOK7V1 influences the malignant phenotype of lung cancer cells through PI3K/AKT/mTOR and FAK/paxillin signaling pathways. International journal of oncology, 2019, Volume: 54, Issue:1 Topics: A549 Cells; Alternative Splicing; Cell Line, Tumor; Down-Regulation; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Muscle Proteins; Paxillin; Phosphatidylinositol 3-Kinases; Prognosis; Proto-Oncogene Proteins c-akt; Signal Transduction; Survival Analysis	2019
ERK2 but not ERK1 mediates HGF-induced motility in non-small cell lung carcinoma cell lines. Journal of cell science, 2013, Jun-01, Volume: 126, Issue:Pt 11 Topics: Carcinoma, Non-Small-Cell Lung; Cell Movement; Focal Adhesions; Glycogen Synthase Kinase 3; HeLa Cells; Hepatocyte Growth Factor; Humans; Lung Neoplasms; MAP Kinase Kinase 1; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Paxillin; Proto-Oncogene Proteins c-met	2013
Furanodiene presents synergistic anti-proliferative activity with paclitaxel via altering cell cycle and integrin signaling in 95-D lung cancer cells. Phytotherapy research : PTR, 2014, Volume: 28, Issue:2 Topics: Cell Cycle; Cell Line, Tumor; Curcuma; Cyclin B1; Cyclin D1; Cyclin-Dependent Kinase 6; Drug Synergism; Drugs, Chinese Herbal; Endoplasmic Reticulum Stress; Focal Adhesion Kinase 1; Furans; Heterocyclic Compounds, 2-Ring; Humans; Integrin beta4; Lung Neoplasms; Paclitaxel; Paxillin; Proto-Oncogene Proteins c-myc; Signal Transduction	2014
Tspan8 and CD151 promote metastasis by distinct mechanisms. European journal of cancer (Oxford, England : 1990), 2013, Volume: 49, Issue:13 Topics: Adenocarcinoma; Animals; Apoptosis; Cell Adhesion; Cell Line, Tumor; Cell Movement; Collagen Type I; Collagen Type IV; Focal Adhesion Kinase 1; Integrin alpha3; Integrin alpha6beta4; Laminin; Lung Neoplasms; Lymphatic Metastasis; Matrix Metalloproteinase 13; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Pancreatic Neoplasms; Paxillin; Phosphorylation; ras Proteins; Rats; RNA Interference; src-Family Kinases; Tetraspanin 24; Tetraspanins; Time Factors; Transfection; Tumor Burden	2013
Paxillin mutations affect focal adhesions and lead to altered mitochondrial dynamics: relevance to lung cancer. Cancer biology & therapy, 2013, Volume: 14, Issue:7 Topics: Focal Adhesions; HEK293 Cells; Humans; Lung Neoplasms; Mitochondrial Dynamics; Mutation; Paxillin	2013
Rab5 activation promotes focal adhesion disassembly, migration and invasiveness in tumor cells. Journal of cell science, 2013, Sep-01, Volume: 126, Issue:Pt 17 Topics: Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Enzyme Activation; Female; Focal Adhesions; Humans; Lung Neoplasms; Neoplasm Invasiveness; Neoplasm Metastasis; Paxillin; rab5 GTP-Binding Proteins; RNA Interference; RNA, Small Interfering; Vinculin	2013
CK2 inhibitor CX-4945 blocks TGF-β1-induced epithelial-to-mesenchymal transition in A549 human lung adenocarcinoma cells. PloS one, 2013, Volume: 8, Issue:9 Topics: Adenocarcinoma; Adenocarcinoma of Lung; Cadherins; Casein Kinase II; Cell Line, Tumor; Cell Movement; Epithelial-Mesenchymal Transition; Focal Adhesion Kinase 1; Humans; Lung Neoplasms; Naphthyridines; Neoplasm Invasiveness; Paxillin; Phenazines; Protein Kinase Inhibitors; Signal Transduction; Smad Proteins; Transforming Growth Factor beta1; Wnt Proteins	2013
Phosphorylation of paxillin confers cisplatin resistance in non-small cell lung cancer via activating ERK-mediated Bcl-2 expression. Oncogene, 2014, Aug-28, Volume: 33, Issue:35 Topics: Animals; Antineoplastic Agents; Benzimidazoles; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cisplatin; Dasatinib; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; MAP Kinase Signaling System; Mice; Mice, Nude; Paxillin; Phosphorylation; Pyrimidines; Thiazoles; Xenograft Model Antitumor Assays	2014
miR-137 impairs the proliferative and migratory capacity of human non-small cell lung cancer cells by targeting paxillin. Human cell, 2014, Volume: 27, Issue:3 Topics: Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Progression; Humans; Lung Neoplasms; MicroRNAs; Molecular Targeted Therapy; Neoplasm Invasiveness; Paxillin	2014
miRNA-491-5p and GIT1 serve as modulators and biomarkers for oral squamous cell carcinoma invasion and metastasis. Cancer research, 2014, Feb-01, Volume: 74, Issue:3 Topics: Adaptor Proteins, Signal Transducing; Animals; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Cycle Proteins; Cell Line, Tumor; Cell Movement; Disease Models, Animal; ErbB Receptors; Focal Adhesion Kinase 1; Focal Adhesions; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; MicroRNAs; Mouth Neoplasms; Neoplasm Invasiveness; Neoplasm Metastasis; Paxillin; Proteolysis; RNA Interference; Signal Transduction	2014
Thapsigargin induces apoptosis by impairing cytoskeleton dynamics in human lung adenocarcinoma cells. TheScientificWorldJournal, 2014, Volume: 2014 Topics: Adenocarcinoma; Apoptosis; Blotting, Western; Calcium; Calcium-Transporting ATPases; Cell Line, Tumor; Cofilin 1; Cytoskeletal Proteins; Cytoskeleton; Endoplasmic Reticulum Stress; Humans; Lung Neoplasms; Paxillin; Thapsigargin	2014
Inhibition of Hedgehog signalling by NVP-LDE225 (Erismodegib) interferes with growth and invasion of human renal cell carcinoma cells. British journal of cancer, 2014, Sep-09, Volume: 111, Issue:6 Topics: Actin Cytoskeleton; Actins; Animals; Antineoplastic Combined Chemotherapy Protocols; Biphenyl Compounds; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Synergism; Everolimus; Hedgehog Proteins; Humans; Indoles; Inhibitory Concentration 50; Kidney Neoplasms; Kruppel-Like Transcription Factors; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Mitogen-Activated Protein Kinases; Neoplasm Micrometastasis; Nuclear Proteins; Paxillin; Proto-Oncogene Proteins c-akt; Pyridines; Pyrroles; Receptors, G-Protein-Coupled; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Sirolimus; Smoothened Receptor; Sunitinib; Transcription Factors; Tumor Burden; Xenograft Model Antitumor Assays; Zinc Finger Protein GLI1; Zinc Finger Protein Gli2	2014
Paxillin promotes colorectal tumor invasion and poor patient outcomes via ERK-mediated stabilization of Bcl-2 protein by phosphorylation at Serine 87. Oncotarget, 2015, Apr-20, Volume: 6, Issue:11 Topics: Animals; Benzimidazoles; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Colorectal Neoplasms; Dasatinib; Enzyme Activation; Enzyme Induction; Extracellular Signal-Regulated MAP Kinases; Heterografts; Humans; Kaplan-Meier Estimate; Leupeptins; Lung Neoplasms; Matrix Metalloproteinase 2; Mice; Mice, Nude; Neoplasm Invasiveness; Neoplasm Proteins; Paxillin; Phosphorylation; Proportional Hazards Models; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-bcl-2; Recombinant Fusion Proteins; RNA Interference; RNA, Small Interfering; Sulfonamides	2015
Paxillin confers resistance to tyrosine kinase inhibitors in EGFR-mutant lung cancers via modulating BIM and Mcl-1 protein stability. Oncogene, 2016, Feb-04, Volume: 35, Issue:5 Topics: Animals; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Cell Line, Tumor; Drug Resistance, Neoplasm; ErbB Receptors; Female; Humans; Lung Neoplasms; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Nude; Myeloid Cell Leukemia Sequence 1 Protein; Paxillin; Protein Kinase Inhibitors; Protein Stability; Proto-Oncogene Proteins; Random Allocation; Xenograft Model Antitumor Assays	2016
Micropillar arrays as potential drug screens: Inhibition of micropillar-mediated activation of the FAK-Src-paxillin signaling pathway by the CK2 inhibitor CX-4945. Acta biomaterialia, 2015, Volume: 27 Topics: Apoptosis; Biological Assay; Casein Kinase II; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Activation; Equipment Design; Equipment Failure Analysis; Focal Adhesion Kinase 1; Humans; Lung Neoplasms; Mechanotransduction, Cellular; Naphthyridines; Paxillin; Phenazines; src-Family Kinases; Tissue Array Analysis; Treatment Outcome	2015
No somatic genetic change in the paxillin gene in nonsmall-cell lung cancer. Molecular carcinogenesis, 2009, Volume: 48, Issue:7 Topics: Axons; Base Sequence; Carcinoma, Non-Small-Cell Lung; DNA Primers; Humans; Introns; Lung Neoplasms; Paxillin; Polymerase Chain Reaction	2009
Increased motility and invasiveness in tumor cells that survive 10 Gy irradiation. Cell structure and function, 2009, Volume: 34, Issue:2 Topics: Carcinoma, Non-Small-Cell Lung; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Survival; Focal Adhesion Kinase 1; Humans; Integrin beta1; Lung Neoplasms; Matrix Metalloproteinase 1; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Paxillin; Radiation Dosage; Vinculin	2009
MET, HGF, EGFR, and PXN gene copy number in lung cancer using DNA extracts from FFPE archival samples and prognostic significance. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 2009, Volume: 28, Issue:2 Topics: Adenocarcinoma; Base Sequence; Cell Line, Tumor; DNA Primers; DNA, Neoplasm; ErbB Receptors; Gene Dosage; Hepatocyte Growth Factor; Humans; Lung Neoplasms; Paxillin; Polymerase Chain Reaction; Prognosis; Proto-Oncogene Proteins c-met	2009
Expression patterns of PAX5, c-Met, and paxillin in neuroendocrine tumors of the lung. Archives of pathology & laboratory medicine, 2010, Volume: 134, Issue:11 Topics: Humans; Immunohistochemistry; Lung Neoplasms; Neuroendocrine Tumors; PAX5 Transcription Factor; Paxillin; Phosphorylation; Proto-Oncogene Proteins c-met; Tissue Array Analysis	2010
Paxillin expression and amplification in early lung lesions of high-risk patients, lung adenocarcinoma and metastatic disease. Journal of clinical pathology, 2011, Volume: 64, Issue:1 Topics: Adenocarcinoma; Adenocarcinoma of Lung; Adenocarcinoma, Bronchiolo-Alveolar; Aged; Biopsy; Chromosomes, Human, Pair 12; Female; Gene Dosage; Genes, erbB-1; Humans; In Situ Hybridization, Fluorescence; Lung Neoplasms; Male; Middle Aged; Mutation; Neoplasm Proteins; Paxillin; Precancerous Conditions; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins	2011
Distinct roles for paxillin and Hic-5 in regulating breast cancer cell morphology, invasion, and metastasis. Molecular biology of the cell, 2011, Feb-01, Volume: 22, Issue:3 Topics: Animals; Breast Neoplasms; Cattle; Cell Adhesion; Cell Line, Tumor; Cell Movement; Extracellular Matrix; Female; Humans; Intracellular Signaling Peptides and Proteins; LIM Domain Proteins; Lung Neoplasms; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Invasiveness; Neoplasm Metastasis; Paxillin; rhoA GTP-Binding Protein; Signal Transduction	2011
Paxillin predicts survival and relapse in non-small cell lung cancer by microRNA-218 targeting. Cancer research, 2010, Dec-15, Volume: 70, Issue:24 Topics: Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Female; Gene Knockdown Techniques; Humans; Lung Neoplasms; Male; MicroRNAs; Molecular Targeted Therapy; Neoplasm Invasiveness; Oncogene Proteins, Viral; Paxillin; Repressor Proteins; RNA, Messenger; Transcription, Genetic; Up-Regulation	2010
A novel sialyltransferase inhibitor suppresses FAK/paxillin signaling and cancer angiogenesis and metastasis pathways. Cancer research, 2011, Jan-15, Volume: 71, Issue:2 Topics: Animals; Cell Line; Cell Line, Tumor; Focal Adhesion Kinase 1; Humans; Integrins; Lithocholic Acid; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Neovascularization, Pathologic; Paxillin; Proteomics; Sialyltransferases; Signal Transduction	2011
Adhesion molecules affected by treatment of lung cancer cells with epidermal growth factor. Lung, 2011, Volume: 189, Issue:5 Topics: Adenocarcinoma; Adenocarcinoma of Lung; beta Catenin; Cadherins; Carcinoma, Non-Small-Cell Lung; Catenins; Cell Adhesion Molecules; Cell Line, Tumor; Crk-Associated Substrate Protein; Delta Catenin; Epidermal Growth Factor; Focal Adhesion Kinase 1; Humans; Lung Neoplasms; Paxillin; rap1 GTP-Binding Proteins; Talin; Vinculin	2011
Expression of focal adhesion kinase in small-cell lung carcinoma. Cancer, 2012, Mar-01, Volume: 118, Issue:5 Topics: Aged; Female; Focal Adhesion Kinase 1; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Paxillin; Phosphorylation; Small Cell Lung Carcinoma; Survival Analysis	2012
The novel indole compound SK228 induces apoptosis and FAK/Paxillin disruption in tumor cell lines and inhibits growth of tumor graft in the nude mouse. International journal of cancer, 2012, Aug-01, Volume: 131, Issue:3 Topics: Actin Cytoskeleton; Animals; Antineoplastic Agents; Apoptosis; Caspase 3; Caspase 8; Caspase 9; Cell Line, Tumor; Cell Proliferation; Cytochromes c; DNA Damage; Esophageal Neoplasms; Focal Adhesion Protein-Tyrosine Kinases; Humans; Indoles; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Mitochondria; Neoplasm Invasiveness; Neoplasms, Experimental; Paxillin; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; rhoA GTP-Binding Protein; Signal Transduction; Xenograft Model Antitumor Assays; Xylenes	2012
Focal adhesion kinase contributes to proliferative potential of ErbB2 mammary tumour cells but is dispensable for ErbB2 mammary tumour induction in vivo. Breast cancer research : BCR, 2012, Feb-28, Volume: 14, Issue:1 Topics: Animals; Apoptosis; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Crk-Associated Substrate Protein; Female; Focal Adhesion Kinase 1; Focal Adhesion Kinase 2; Gene Deletion; Integrases; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Neoplasm Transplantation; Paxillin; Phosphorylation; Receptor, ErbB-2; Tumor Burden	2012
[Relationship of the expression of CD44v6 and paxillin to the prognosis of non-small cell lung carcinoma]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2003, Volume: 34, Issue:3 Topics: Adult; Aged; Carcinoma, Non-Small-Cell Lung; Cell Adhesion Molecules; Cytoskeletal Proteins; Female; Glycoproteins; Humans; Hyaluronan Receptors; Immunohistochemistry; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Paxillin; Phosphoproteins; Prognosis	2003
c-MET mutational analysis in small cell lung cancer: novel juxtamembrane domain mutations regulating cytoskeletal functions. Cancer research, 2003, Oct-01, Volume: 63, Issue:19 Topics: Alternative Splicing; Animals; Carcinoma, Small Cell; Cell Adhesion; Cell Division; Cell Line, Tumor; Cell Movement; Cytoskeletal Proteins; Cytoskeleton; DNA Mutational Analysis; Humans; Lung Neoplasms; Mice; Mutation, Missense; Paxillin; Phosphoproteins; Phosphorylation; Protein Isoforms; Protein Structure, Tertiary; Proto-Oncogene Proteins c-met; Rats; Signal Transduction; Transfection	2003
Ionizing radiation modules of the expression and tyrosine phosphorylation of the focal adhesion-associated proteins focal adhesion kinase (FAK) and its substrates p130cas and paxillin in A549 human lung carcinoma cells in vitro. International journal of radiation biology, 2003, Volume: 79, Issue:9 Topics: Cell Line, Tumor; Crk-Associated Substrate Protein; Cytoskeletal Proteins; Dose-Response Relationship, Radiation; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation, Enzymologic; Humans; Lung Neoplasms; Paxillin; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Proteins; Radiation Dosage; Radiation, Ionizing; Retinoblastoma-Like Protein p130; Tyrosine; X-Rays	2003
Overexpression of hyperactive integrin-linked kinase leads to increased cellular radiosensitivity. Cancer research, 2004, Aug-15, Volume: 64, Issue:16 Topics: Actins; Cell Line, Tumor; Cyclin D1; Cytoskeletal Proteins; Extracellular Matrix Proteins; Focal Adhesions; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Integrin beta1; Lung Neoplasms; MAP Kinase Signaling System; Paxillin; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Radiation Tolerance; Retinoblastoma Protein; Subcellular Fractions; Transfection; Tyrosine	2004
Crk-associated substrate tyrosine phosphorylation sites are critical for invasion and metastasis of SRC-transformed cells. Molecular cancer research : MCR, 2005, Volume: 3, Issue:6 Topics: Animals; Binding Sites; Cell Line, Transformed; Cell Movement; Cells, Cultured; Collagen; Cytoskeletal Proteins; Drug Combinations; Enzyme Activation; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Genes, src; Injections, Subcutaneous; Laminin; Lung Neoplasms; Matrix Metalloproteinase 2; Mice; Mice, Nude; Neoplasm Invasiveness; Neoplasm Transplantation; Oncogene Protein v-crk; Paxillin; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Proteoglycans; Retroviridae Proteins, Oncogenic; src Homology Domains; Tyrosine	2005
Dasatinib (BMS-354825) tyrosine kinase inhibitor suppresses invasion and induces cell cycle arrest and apoptosis of head and neck squamous cell carcinoma and non-small cell lung cancer cells. Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Oct-01, Volume: 11, Issue:19 Pt 1 Topics: Adenosine Triphosphate; Antineoplastic Agents; Apoptosis; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Collagen; Crk-Associated Substrate Protein; Dasatinib; Dose-Response Relationship, Drug; Drug Combinations; Enzyme Inhibitors; Focal Adhesion Protein-Tyrosine Kinases; G1 Phase; Gentian Violet; Head and Neck Neoplasms; Humans; Immunoprecipitation; Inhibitory Concentration 50; Laminin; Lung Neoplasms; Neoplasm Invasiveness; Neovascularization, Pathologic; Paxillin; Phosphorylation; Protein-Tyrosine Kinases; Proteoglycans; Pyrimidines; Retinoblastoma Protein; S Phase; Signal Transduction; src-Family Kinases; Thiazoles; Time Factors; Trypan Blue	2005
Ionising radiation induces changes associated with epithelial-mesenchymal transdifferentiation and increased cell motility of A549 lung epithelial cells. European journal of cancer (Oxford, England : 1990), 2007, Volume: 43, Issue:7 Topics: Actins; Adenocarcinoma; Cell Adhesion; Cell Movement; Cell Transformation, Neoplastic; Epithelial Cells; Focal Adhesion Kinase 1; Humans; Lung Neoplasms; p38 Mitogen-Activated Protein Kinases; Paxillin; Phosphorylation; Radiation, Ionizing; RNA, Messenger; Tumor Cells, Cultured	2007
CNTO 95, a fully human anti alphav integrin antibody, inhibits cell signaling, migration, invasion, and spontaneous metastasis of human breast cancer cells. Clinical & experimental metastasis, 2008, Volume: 25, Issue:2 Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Female; Focal Adhesion Kinase 1; Humans; Integrin alphaV; Lung Neoplasms; Mice; Mice, SCID; Neoplasm Invasiveness; Paxillin; Phosphorylation; Signal Transduction; Transplantation, Heterologous; Vitronectin	2008
Paxillin is a target for somatic mutations in lung cancer: implications for cell growth and invasion. Cancer research, 2008, Jan-01, Volume: 68, Issue:1 Topics: Animals; Cell Proliferation; Gene Dosage; Genes, erbB-1; Humans; Lung Neoplasms; Mice; Mice, Inbred Strains; Mutation; Neoplasm Invasiveness; Paxillin; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-met; RNA Interference	2008
Src inhibitors in early breast cancer: a methodology, feasibility and variability study. Breast cancer research and treatment, 2009, Volume: 114, Issue:2 Topics: Animals; Benzodioxoles; Breast Neoplasms; CSK Tyrosine-Protein Kinase; Feasibility Studies; Female; Focal Adhesion Kinase 1; Humans; Immunoenzyme Techniques; Lung Neoplasms; Paxillin; Phosphorylation; Protein-Tyrosine Kinases; Quinazolines; Rats; Rats, Nude; src-Family Kinases; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2009
Expression of the focal adhesion protein paxillin in lung cancer and its relation to cell motility. Oncogene, 1999, Jan-07, Volume: 18, Issue:1 Topics: 3T3 Cells; Animals; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cell Adhesion Molecules; Cell Movement; Cytoskeletal Proteins; Gene Expression; Humans; Lung Neoplasms; Mice; Paxillin; Phosphoproteins; Recombinant Fusion Proteins; Tumor Cells, Cultured	1999
Bombesin and gastrin releasing peptide increase tyrosine phosphorylation of focal adhesion kinase and paxillin in non-small cell lung cancer cells. Cancer letters, 2001, Jan-10, Volume: 162, Issue:1 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Bombesin; Carcinoma, Non-Small-Cell Lung; Cell Division; Cytoskeletal Proteins; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Gastrin-Releasing Peptide; Genistein; Humans; Lung Neoplasms; Paxillin; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Tumor Cells, Cultured; Tyrosine	2001