paxilline has been researched along with Disease Exacerbation in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (13.79) | 29.6817 |
| 2010's | 19 (65.52) | 24.3611 |
| 2020's | 6 (20.69) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, Y; Ding, X; Li, M; Li, Y; Liu, B; Shen, H; Wang, Y; Xie, SM; Xing, L | 1 |
| Chen, S; Hu, J; Ma, Y; Wang, J; Wang, X; Wen, L; Wu, T; Yue, T; Zhang, J; Zhang, X; Zhu, J | 1 |
| Guo, M; He, B; He, Y; Xiao, F; Yan, H; Yi, L; Zou, J | 1 |
| Bach, DH; Bayraktar, E; Cho, MS; Choi, HJ; Dasari, SK; Ivan, C; Kim, MS; Lopez-Berestein, G; Mangala, LS; Noh, K; Pradeep, S; Rodriguez-Aguayo, C; Sood, AK; Stur, E; Wu, SY | 1 |
| Antoniades, I; Charalambous, A; Christodoulou, A; Christoforou, M; Kalalidou, K; Kyriakou, M; Skourides, PA | 1 |
| Gu, H; Wen, J | 1 |
| Alexandrou, P; Coutts, RH; Danas, E; Giaginis, C; Klijanienko, J; Kotta-Loizou, I; Tasoulas, J; Theocharis, S; Tsoukalas, N; Tsourouflis, G | 1 |
| Alaoui-Jamali, MA; Bijian, K; Chang, CH; Dahabieh, MS; Miller, WH; Qiu, D; Saad, A; Su, J | 1 |
| Chen, L; Li, J; Liu, Q; Qi, X; Qiu, H; Tang, M; Wang, J; Wang, Y; Yu, J | 1 |
| Bruggeman, LA; Byfield, FJ; Chang, AN; Cruz, K; Doelger, R; Embry, AE; Gillombardo, CB; Henderson, JM; Hussain, RZ; Janmey, PA; Liu, L; Liu, Z; Miller, RT; Moradi, S; Stuve, O; Wu, Z; Yoon, J | 1 |
| Deng, Y; Ding, Q; He, K; Li, H; Mu, G; Wu, L; Xu, M; Yang, D; Yu, H; Zhang, L; Zhou, J | 1 |
| Chen, HM; Cheng, YM; Lin, YH; Tsai, SJ; Wing, LY | 1 |
| Bai, L; Chen, DL; Li, YH; Luo, HY; Qiu, MZ; Ren, C; Wang, DS; Wang, F; Wang, FH; Wang, ZQ; Xu, RH; Zeng, ZL; Zhang, DS | 1 |
| Bi, H; Bi, Y; Gao, F; Han, Y; Wang, X | 1 |
| Chen, H; Fan, KH; Jiang, Y; Jin, WH; Jing, L; Ren, JD; Wang, SH; Wu, J; Wu, XC; Xing, YJ; Yu, BT | 1 |
| Dai, JF; Ding, QS; Li, YX; Mu, GG; Shi, YB; Yu, HG; Zhang, LL | 1 |
| Matsuyama, R; Okada, M; Okuzaki, D; Oneyama, C | 1 |
| Bao, ZS; Jiang, T; Jin, S; Liang, JS; Sun, LH; Wang, HJ; Wang, Z; Wu, YP; Yang, FQ; Yang, ZX; Zhang, CB | 1 |
| Huang, CY; Lin, FY; Lin, YW; Lu, HY; Shih, CC; Shih, CM; Tsai, CS | 1 |
| Albitar, L; Aponte, M; Cramer, DW; Edwards, D; Jiang, W; Lakkis, M; Li, MJ; Mok, SC; Vitonis, A; Ye, B | 1 |
| Bu, Y; Gelman, IH; Sachdev, S | 1 |
| Elbling, L; Fiebiger, E; Gerner, C; Jäger, W; Kunstfeld, R; Mikula, M; Paulitschke, V; Pehamberger, H; Riemer, AB; Scheiner, O; Schicher, N; Swoboda, A; Szekeres, T; Trimurtulu, G; Venkateswarlu, S | 1 |
| Chen, XL; Kim, L; Lim, ST; Miller, NL; Nam, JO; Schlaepfer, DD; Shi, L; Tanjoni, I; Tomar, A; Walsh, C; Yu, HG | 1 |
| Berchtold, S; Erkan, M; Esposito, I; Höfler, H; Paron, I; Shamarla, M; Vörös, J | 1 |
| Aroukatos, P; Athanasopoulou, A; Bravou, V; Nakas, D; Papadaki, H; Repanti, M | 1 |
| Hwang, Y; Jo, JY; Kim, JM; Kim, S; Kim, SJ; Koh, SS; Lee, DK; Park, EH; Song, SY | 1 |
| Chen, DL; Kang, TB; Li, YH; Luo, HY; Qiu, MZ; Ren, C; Wang, DS; Wang, FH; Wang, ZQ; Wu, WJ; Xu, RH; Zeng, ZL; Zhang, DS | 1 |
| Lai, YJ; Lin, FT; Lin, WC; Xu, J | 1 |
| Bar-Shavit, R; Lotem, M; Maoz, M; Pokroy, E; Salah, Z; Uziely, B | 1 |
29 other study(ies) available for paxilline and Disease Exacerbation
| Article | Year |
|---|---|
ETV4 overexpression promotes progression of non-small cell lung cancer by upregulating PXN and MMP1 transcriptionally.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Matrix Metalloproteinase 1; Mice, Inbred BALB C; Mice, Nude; Paxillin; Proto-Oncogene Proteins c-ets; Transcriptional Activation | 2020 |
Paxillin knockdown suppresses metastasis and epithelial‑mesenchymal transition in colorectal cancer via the ERK signalling pathway.
Topics: Aged; Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colon; Colorectal Neoplasms; Desmosomes; Disease Progression; Epithelial-Mesenchymal Transition; Extracellular Signal-Regulated MAP Kinases; Female; Follow-Up Studies; Humans; Intestinal Mucosa; Liver; Liver Neoplasms; Lymphatic Metastasis; Male; MAP Kinase Signaling System; Mice; Microscopy, Electron, Transmission; Microvilli; Middle Aged; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Paxillin; Retrospective Studies; Xenograft Model Antitumor Assays | 2020 |
Promotive effect of Talin-1 protein on gastric cancer progression through PTK2-PXN-VCL-E-Cadherin-CAPN2-MAPK1 signaling axis.
Topics: Antigens, CD; Cadherins; Calpain; Cell Line, Tumor; Disease Progression; Focal Adhesion Kinase 1; Humans; Immunohistochemistry; MAP Kinase Signaling System; Paxillin; Stomach; Stomach Neoplasms; Talin; Vinculin | 2020 |
The hidden role of paxillin: localization to nucleus promotes tumor angiogenesis.
Topics: Animals; Apoptosis; Biomarkers, Tumor; Cell Nucleus; Cell Proliferation; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Nude; Neovascularization, Pathologic; Ovarian Neoplasms; Paxillin; Prognosis; src-Family Kinases; Survival Rate; Tissue Plasminogen Activator; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2021 |
FAK displacement from focal adhesions: a promising strategy to target processes implicated in cancer progression and metastasis.
Topics: Cell Line; Cell Movement; Disease Progression; Focal Adhesion Protein-Tyrosine Kinases; Focal Adhesions; Humans; Neoplasms; Paxillin; Protein Domains | 2021 |
Abnormal level of paxillin in cervical cancer cells is involved in tumor progression and invasion.
Topics: Carcinogenesis; Carcinoma, Squamous Cell; Cell Movement; Cells, Cultured; Disease Progression; DNA, Viral; Female; Human papillomavirus 16; Humans; Neoplasm Invasiveness; Papillomavirus E7 Proteins; Papillomavirus Infections; Paxillin; Prognosis; Transfection; Up-Regulation; Uterine Cervical Neoplasms | 2021 |
Expression and Clinical Significance of Concomitant FAK/SRC and p-Paxillin in Mobile Tongue Squamous Cell Carcinoma.
Topics: Aged; Carcinoma, Squamous Cell; Cell Differentiation; Disease Progression; Disease-Free Survival; Female; Focal Adhesion Protein-Tyrosine Kinases; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Lymphatic Metastasis; Male; Middle Aged; Paxillin; Prognosis; Proportional Hazards Models; src-Family Kinases; Tongue Neoplasms; Treatment Outcome | 2017 |
Endosomal sorting and c-Cbl targeting of paxillin to autophagosomes regulate cell-matrix adhesion turnover in human breast cancer cells.
Topics: Autophagosomes; Autophagy; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Disease Progression; Endosomes; Extracellular Matrix; Gene Knockdown Techniques; Humans; Microtubule-Associated Proteins; Neoplasm Metastasis; Paxillin; Phosphorylation; Protein Binding; Proteolysis; Proto-Oncogene Proteins c-cbl; rab GTP-Binding Proteins; rab7 GTP-Binding Proteins; Signal Transduction | 2017 |
The overexpression of PXN promotes tumor progression and leads to radioresistance in cervical cancer.
Topics: Adult; Aged; Animals; Apoptosis; Case-Control Studies; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Disease Progression; Female; Gene Expression; Gene Knockdown Techniques; Humans; Mice; Middle Aged; Neoplasm Grading; Neoplasm Metastasis; Neoplasm Staging; Paxillin; Prognosis; Radiation Tolerance; Uterine Cervical Neoplasms; Xenograft Model Antitumor Assays | 2018 |
Similar Biophysical Abnormalities in Glomeruli and Podocytes from Two Distinct Models.
Topics: Animals; Biophysical Phenomena; Cell Adhesion; Collagen; Cytoskeleton; Disease Models, Animal; Disease Progression; Elastic Modulus; Glomerulonephritis; HIV; Kidney Glomerulus; Mice; Mice, Transgenic; Microscopy, Atomic Force; Microscopy, Fluorescence; Nephrosis, Lipoid; Paxillin; Podocytes; Protamines; Real-Time Polymerase Chain Reaction | 2018 |
Gastrin stimulates pancreatic cancer cell directional migration by activating the Gα12/13-RhoA-ROCK signaling pathway.
Topics: Animals; Cell Line, Tumor; Cell Movement; Cell Polarity; Disease Progression; Focal Adhesions; Gastrins; Golgi Apparatus; GTP-Binding Protein alpha Subunits, G12-G13; Humans; Mice, Inbred BALB C; Mice, Nude; Models, Biological; Neoplasm Invasiveness; Organic Chemicals; Pancreatic Neoplasms; Paxillin; Phosphorylation; Phosphotyrosine; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Time Factors | 2018 |
Overexpression of integrin-β1 in leiomyoma promotes cell spreading and proliferation.
Topics: Antigens, Neoplasm; Cell Adhesion; Cell Movement; Cell Proliferation; Cell Shape; Cyclin D1; Disease Progression; Disintegrins; Extracellular Matrix Proteins; Female; Focal Adhesion Protein-Tyrosine Kinases; Humans; Integrin beta1; Leiomyoma; Paxillin; Phosphorylation; Protein Processing, Post-Translational; RNA Interference; RNA, Small Interfering; Tumor Cells, Cultured; Up-Regulation; Uterine Neoplasms | 2013 |
Abnormal expression of paxillin correlates with tumor progression and poor survival in patients with gastric cancer.
Topics: Adult; Aged; Base Sequence; Blotting, Western; Cell Line, Tumor; Disease Progression; DNA Primers; Female; Humans; Male; Middle Aged; Paxillin; Real-Time Polymerase Chain Reaction; Stomach Neoplasms; Survival Rate | 2013 |
miR-137 impairs the proliferative and migratory capacity of human non-small cell lung cancer cells by targeting paxillin.
Topics: Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Progression; Humans; Lung Neoplasms; MicroRNAs; Molecular Targeted Therapy; Neoplasm Invasiveness; Paxillin | 2014 |
Pharmacological blockade of the MaxiK channel attenuates experimental acute pancreatitis and associated lung injury in rats.
Topics: Animals; Chemokine CXCL2; Disease Progression; Humans; Large-Conductance Calcium-Activated Potassium Channels; Liver; Lung; Lung Injury; Macrophages; Male; Mice; Models, Animal; Pancreatitis, Acute Necrotizing; Paxillin; Rats; Rats, Wistar; Taurocholic Acid; Tumor Necrosis Factor-alpha | 2014 |
Phosphatase and Tensin Homolog (PTEN) Represses Colon Cancer Progression through Inhibiting Paxillin Transcription via PI3K/AKT/NF-κB Pathway.
Topics: Animals; Base Sequence; Chromatin Immunoprecipitation; Colonic Neoplasms; Disease Progression; DNA; DNA Primers; Humans; Mice; Mice, Nude; NF-kappa B; Paxillin; Phosphatidylinositol 3-Kinases; Promoter Regions, Genetic; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Real-Time Polymerase Chain Reaction; Transcription, Genetic | 2015 |
MicroRNA-27b suppresses tumor progression by regulating ARFGEF1 and focal adhesion signaling.
Topics: Animals; Colonic Neoplasms; CSK Tyrosine-Protein Kinase; Disease Models, Animal; Disease Progression; Focal Adhesions; Gene Expression Regulation, Neoplastic; Guanine Nucleotide Exchange Factors; HCT116 Cells; Heterografts; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Neoplasm Invasiveness; Paxillin; src-Family Kinases | 2016 |
Overexpression of Paxillin Correlates with Tumor Progression and Predicts Poor Survival in Glioblastoma.
Topics: Adult; Aged; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Databases, Nucleic Acid; Disease Progression; Female; Glioblastoma; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Paxillin; RNA, Messenger; RNA, Small Interfering | 2017 |
A potential contribution of dipeptidyl peptidase-4 by the mediation of monocyte differentiation in the development and progression of abdominal aortic aneurysms.
Topics: Aged; Aged, 80 and over; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Case-Control Studies; Cell Differentiation; Cell Line, Tumor; Dilatation, Pathologic; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Disease Progression; Extracellular Signal-Regulated MAP Kinases; Female; Focal Adhesion Kinase 2; Glucagon-Like Peptide 1; Humans; Macrophages; Male; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Paxillin; RNA Interference; Transfection | 2017 |
Activation of platelet-activating factor receptor and pleiotropic effects on tyrosine phospho-EGFR/Src/FAK/paxillin in ovarian cancer.
Topics: Cell Line, Tumor; Disease Progression; ErbB Receptors; Female; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Models, Biological; Neoplasm Invasiveness; Ovarian Neoplasms; Paxillin; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Signal Transduction; src-Family Kinases; Tyrosine | 2008 |
Paxillin-Y118 phosphorylation contributes to the control of Src-induced anchorage-independent growth by FAK and adhesion.
Topics: Animals; Cell Adhesion; Cell Culture Techniques; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Disease Models, Animal; Disease Progression; Fibroblasts; Focal Adhesion Protein-Tyrosine Kinases; Humans; Immunoblotting; Mice; Neoplastic Processes; Neovascularization, Pathologic; Paxillin; Phosphorylation; src-Family Kinases; Transfection | 2009 |
3,3',4,4',5,5'-hexahydroxystilbene impairs melanoma progression in a metastatic mouse model.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p21; Disease Models, Animal; Disease Progression; DNA Damage; Dose-Response Relationship, Drug; Female; Humans; Melanoma; Mice; Mice, SCID; Paxillin; Pyrogallol; Skin Neoplasms; Stilbenes; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2010 |
p190RhoGEF (Rgnef) promotes colon carcinoma tumor progression via interaction with focal adhesion kinase.
Topics: Amino Acid Sequence; Animals; Caco-2 Cells; Cell Movement; Colorectal Neoplasms; Disease Progression; Enzyme Activation; Extracellular Matrix; Female; Focal Adhesion Kinase 1; Gastrins; Gene Knockdown Techniques; Guanine Nucleotide Exchange Factors; HCT116 Cells; Humans; Mice; Mice, Nude; Molecular Sequence Data; Paxillin; Phosphorylation; Signal Transduction | 2011 |
Tenascin-C enhances pancreatic cancer cell growth and motility and affects cell adhesion through activation of the integrin pathway.
Topics: Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Disease Progression; Enzyme Activation; Epithelial Cells; Extracellular Matrix; Fibronectins; Gene Expression Regulation, Neoplastic; Humans; Integrins; Pancreatic Neoplasms; Paxillin; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Tenascin | 2011 |
Decreased ezrin and paxillin expression in human urothelial bladder tumors correlate with tumor progression.
Topics: Antigens, CD; beta Catenin; Cadherins; Cell Adhesion; Cytoskeletal Proteins; Disease Progression; Gene Expression Profiling; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Multivariate Analysis; Neoplasm Invasiveness; Paxillin; Signal Transduction; Tumor Suppressor Protein p53; Urinary Bladder Neoplasms; Urothelium | 2013 |
Collagen triple helix repeat containing-1 promotes pancreatic cancer progression by regulating migration and adhesion of tumor cells.
Topics: Animals; Carcinoma, Pancreatic Ductal; Case-Control Studies; Cell Adhesion; Cell Line, Tumor; Cell Movement; Disease Progression; Enzyme Activation; Epithelium; Extracellular Matrix Proteins; Focal Adhesion Kinase 1; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Pancreas; Pancreatic Neoplasms; Paxillin; rac1 GTP-Binding Protein; Signal Transduction; src-Family Kinases; Up-Regulation | 2013 |
Overexpression of paxillin induced by miR-137 suppression promotes tumor progression and metastasis in colorectal cancer.
Topics: Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Disease Progression; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Paxillin; Prognosis; RNA Interference; RNA, Messenger; RNA, Small Interfering; Transplantation, Heterologous | 2013 |
TRIP6 enhances lysophosphatidic acid-induced cell migration by interacting with the lysophosphatidic acid 2 receptor.
Topics: Adaptor Proteins, Signal Transducing; Animals; ATPases Associated with Diverse Cellular Activities; Carrier Proteins; Cell Line, Tumor; Cell Movement; Cytoskeletal Proteins; Disease Progression; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Glutathione Transferase; Green Fluorescent Proteins; Humans; LIM Domain Proteins; Luminescent Proteins; Lysophospholipids; Mice; Microscopy, Fluorescence; Mutation; NIH 3T3 Cells; Paxillin; Phosphoproteins; Plasmids; Precipitin Tests; Proteasome Endopeptidase Complex; Protein Binding; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Receptors, G-Protein-Coupled; Receptors, Lysophosphatidic Acid; Reverse Transcriptase Polymerase Chain Reaction; rho GTP-Binding Proteins; RNA, Small Interfering; Signal Transduction; src-Family Kinases; Transcription Factors; Two-Hybrid System Techniques | 2004 |
Protease-activated receptor-1 (hPar1), a survival factor eliciting tumor progression.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Bcl-2-Like Protein 11; Cell Line, Tumor; Cell Survival; Disease Progression; DNA, Antisense; Gene Expression Regulation, Neoplastic; Humans; Membrane Proteins; Mice; Mice, Nude; Neoplasm Invasiveness; Neoplasm Transplantation; Neoplasms; Paxillin; Phosphorylation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptor, PAR-1 | 2007 |