paxilline has been researched along with Colorectal Cancer in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (16.67) | 29.6817 |
| 2010's | 14 (77.78) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, S; Hu, J; Ma, Y; Wang, J; Wang, X; Wen, L; Wu, T; Yue, T; Zhang, J; Zhang, X; Zhu, J | 1 |
| Shi, YB; Zhang, LF; Zhang, LL | 1 |
| Li, T; Liu, Y; Wan, Y; Wang, X; Yin, H; Zhang, Q; Zhu, J | 1 |
| Chang, SW; Chen, TH; Huang, CC; Lee, H; Wu, DW | 1 |
| Huang, CC; Lee, H; Lin, PL; Wu, DW | 1 |
| Fukumoto, M; Kurisu, S; Takenawa, T; Yamada, T | 1 |
| Jiang, H; Jiang, Y; Qin, J; Wang, F; Wang, Z; Xu, J | 1 |
| Dang, XB; Du, SK; Gong, M; Zhao, CJ | 1 |
| Du, C; Liu, X; Liu, Y; Wang, X; Zhang, J; Zhu, J | 1 |
| Aalbers, RI; de Heer, P; Koudijs, MM; Kuppen, PJ; Morreau, J; Putter, H; Tollenaar, RA; van de Velde, CJ; van de Water, B | 1 |
| Asano, M; Dawson, D; Guda, K; Iwakura, Y; Lawrence, E; Markowitz, SD; Satake, M; Sun, Q; Wang, Z; Watanabe, T; Wei, L; Willis, J; Yang, Z; Zhang, X; Zhao, Y; Zheng, W | 1 |
| Chen, XL; Kim, L; Lim, ST; Miller, NL; Nam, JO; Schlaepfer, DD; Shi, L; Tanjoni, I; Tomar, A; Walsh, C; Yu, HG | 1 |
| Ahn, KJ; Chang, CH; Jo, YS; Kang, JK; Kang, YJ; Kim, H; Kim, SK; Nam, HJ; Park, SJ; Seok, H; Shong, M | 1 |
| Elliott, VA; Evers, BM; Gulhati, P; Lee, EY; Morris, AJ; Mustain, WC; O'Connor, K; Rychahou, PG; Sunkara, M; Weiss, HL; Zaytseva, YY | 1 |
| Chen, DL; Kang, TB; Li, YH; Luo, HY; Qiu, MZ; Ren, C; Wang, DS; Wang, FH; Wang, ZQ; Wu, WJ; Xu, RH; Zeng, ZL; Zhang, DS | 1 |
| Cushman, I; Hurwitz, HI; Jia, J; Liu, Y; Marshall, DJ; Nixon, AB; Starodub, A | 1 |
| Dong, JM; Manser, E; Quah, SY; Tang, JP; Wang, H; Zeng, Q | 1 |
| Ayaki, M; Ishiguro, S; Kameyama, M; Komatsu, K; Miyoshi, J; Mukai, M; Murata, K; Nakamura, H; Tatsuta, M | 1 |
1 trial(s) available for paxilline and Colorectal Cancer
| Article | Year |
|---|---|
Bcl-2 stabilization by paxillin confers 5-fluorouracil resistance in colorectal cancer.
Topics: Amino Acid Substitution; Cell Line, Tumor; Colorectal Neoplasms; Drug Resistance, Neoplasm; Female; Fluorouracil; Follow-Up Studies; Gene Expression Regulation, Neoplastic; Humans; Male; Mutation, Missense; p21-Activated Kinases; Paxillin; Proto-Oncogene Proteins c-bcl-2; Retrospective Studies | 2015 |
17 other study(ies) available for paxilline and Colorectal Cancer
| Article | Year |
|---|---|
Paxillin knockdown suppresses metastasis and epithelial‑mesenchymal transition in colorectal cancer via the ERK signalling pathway.
Topics: Aged; Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colon; Colorectal Neoplasms; Desmosomes; Disease Progression; Epithelial-Mesenchymal Transition; Extracellular Signal-Regulated MAP Kinases; Female; Follow-Up Studies; Humans; Intestinal Mucosa; Liver; Liver Neoplasms; Lymphatic Metastasis; Male; MAP Kinase Signaling System; Mice; Microscopy, Electron, Transmission; Microvilli; Middle Aged; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Paxillin; Retrospective Studies; Xenograft Model Antitumor Assays | 2020 |
miR-24 inhibited the killing effect of natural killer cells to colorectal cancer cells by downregulating Paxillin.
Topics: Animals; Case-Control Studies; Cell Line; Cell Line, Tumor; Colorectal Neoplasms; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Female; Gene Expression Regulation, Neoplastic; Humans; Interferon-gamma; Killer Cells, Natural; Mice; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Paxillin; Reverse Transcriptase Polymerase Chain Reaction; Tumor Necrosis Factor-alpha | 2018 |
Role of paxillin in colorectal carcinoma and its relationship to clinicopathological features.
Topics: Apoptosis; Biomarkers, Tumor; Carcinoembryonic Antigen; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Female; Humans; Immunohistochemistry; In Vitro Techniques; Male; Paxillin; RNA, Small Interfering | 2014 |
Paxillin promotes colorectal tumor invasion and poor patient outcomes via ERK-mediated stabilization of Bcl-2 protein by phosphorylation at Serine 87.
Topics: Animals; Benzimidazoles; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Colorectal Neoplasms; Dasatinib; Enzyme Activation; Enzyme Induction; Extracellular Signal-Regulated MAP Kinases; Heterografts; Humans; Kaplan-Meier Estimate; Leupeptins; Lung Neoplasms; Matrix Metalloproteinase 2; Mice; Mice, Nude; Neoplasm Invasiveness; Neoplasm Proteins; Paxillin; Phosphorylation; Proportional Hazards Models; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-bcl-2; Recombinant Fusion Proteins; RNA Interference; RNA, Small Interfering; Sulfonamides | 2015 |
α-Actinin-4 enhances colorectal cancer cell invasion by suppressing focal adhesion maturation.
Topics: Actinin; Caco-2 Cells; Cell Line, Tumor; Cell Movement; Colorectal Neoplasms; Focal Adhesions; HT29 Cells; Humans; Microscopy, Fluorescence; Neoplasm Invasiveness; Paxillin; Protein Binding; Recombinant Proteins; RNA Interference; RNA, Small Interfering; Zyxin | 2015 |
MicroRNA-145 suppresses cell migration and invasion by targeting paxillin in human colorectal cancer cells.
Topics: Cell Line, Tumor; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; Neoplasm Invasiveness; Paxillin | 2015 |
Expression of Paxillin is Correlated with Clinical Prognosis in Colorectal Cancer Patients.
Topics: Biomarkers, Tumor; Colorectal Neoplasms; Female; Humans; Male; Middle Aged; Paxillin; Prognosis; Real-Time Polymerase Chain Reaction | 2015 |
Paxillin is positively correlated with the clinicopathological factors of colorectal cancer, and knockdown of Paxillin improves sensitivity to cetuximab in colorectal cancer cells.
Topics: Caco-2 Cells; Cell Line, Tumor; Cell Proliferation; Cetuximab; Colorectal Neoplasms; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; HT29 Cells; Humans; Paxillin; Prognosis; Survival Analysis | 2016 |
Combined expression of the non-receptor protein tyrosine kinases FAK and Src in primary colorectal cancer is associated with tumor recurrence and metastasis formation.
Topics: Adolescent; Adult; Biomarkers, Tumor; Child; Child, Preschool; Colorectal Neoplasms; Female; Focal Adhesion Protein-Tyrosine Kinases; Humans; Immunohistochemistry; Infant; Infant, Newborn; Liver Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Paxillin; Prognosis; src-Family Kinases | 2008 |
Identification and functional characterization of paxillin as a target of protein tyrosine phosphatase receptor T.
Topics: Animals; Azoxymethane; Blotting, Western; Cell Line; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Female; HCT116 Cells; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; Mutation; Neoplasms, Experimental; Paxillin; Phosphorylation; Receptor-Like Protein Tyrosine Phosphatases, Class 2; Substrate Specificity; Transfection; Transplantation, Heterologous; Tyrosine | 2010 |
p190RhoGEF (Rgnef) promotes colon carcinoma tumor progression via interaction with focal adhesion kinase.
Topics: Amino Acid Sequence; Animals; Caco-2 Cells; Cell Movement; Colorectal Neoplasms; Disease Progression; Enzyme Activation; Extracellular Matrix; Female; Focal Adhesion Kinase 1; Gastrins; Gene Knockdown Techniques; Guanine Nucleotide Exchange Factors; HCT116 Cells; Humans; Mice; Mice, Nude; Molecular Sequence Data; Paxillin; Phosphorylation; Signal Transduction | 2011 |
Downregulation of erythropoietin receptor by overexpression of phospholipase C-gamma 1 is critical for decrease on focal adhesion in transformed cells.
Topics: Animals; Cell Adhesion; Cell Movement; Cell Transformation, Neoplastic; Colorectal Neoplasms; Down-Regulation; Erythropoietin; Fibroblasts; Focal Adhesions; Humans; Male; Mice; Middle Aged; Paxillin; PC12 Cells; Phospholipase C gamma; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Rats; Receptors, Erythropoietin; Signal Transduction | 2011 |
Inhibition of fatty acid synthase attenuates CD44-associated signaling and reduces metastasis in colorectal cancer.
Topics: Animals; Cell Line, Tumor; Colorectal Neoplasms; Down-Regulation; Fatty Acid Synthases; Focal Adhesion Kinase 1; Gene Knockdown Techniques; Humans; Hyaluronan Receptors; Lipogenesis; Liver Neoplasms; Male; Mice; Mice, Nude; Oncogene Protein v-akt; Paxillin; Proto-Oncogene Proteins c-met; Signal Transduction; Xenograft Model Antitumor Assays | 2012 |
Overexpression of paxillin induced by miR-137 suppression promotes tumor progression and metastasis in colorectal cancer.
Topics: Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Disease Progression; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Paxillin; Prognosis; RNA Interference; RNA, Messenger; RNA, Small Interfering; Transplantation, Heterologous | 2013 |
Dual inhibition of αV integrins and Src kinase activity as a combination therapy strategy for colorectal cancer.
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Dasatinib; Focal Adhesion Kinase 1; Human Umbilical Vein Endothelial Cells; Humans; Integrin alphaV; Paxillin; Phosphorylation; Pyrimidines; Signal Transduction; src-Family Kinases; Thiazoles | 2013 |
PRL-3 down-regulates PTEN expression and signals through PI3K to promote epithelial-mesenchymal transition.
Topics: Actins; Animals; CHO Cells; Colorectal Neoplasms; Cricetinae; Cricetulus; Down-Regulation; Epithelial Cells; HeLa Cells; Humans; Mesoderm; Neoplasm Proteins; Paxillin; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Tyrosine Phosphatases; PTEN Phosphohydrolase; rac1 GTP-Binding Protein; rhoA GTP-Binding Protein; Signal Transduction; Transfection; Vinculin | 2007 |
Reduced expression of focal adhesion kinase in liver metastases compared with matched primary human colorectal adenocarcinomas.
Topics: Adenocarcinoma; Blotting, Western; Colorectal Neoplasms; Cytoskeletal Proteins; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Immunohistochemistry; Liver Neoplasms; Paxillin; Phosphoproteins; Protein-Tyrosine Kinases; Talin; Vinculin | 2001 |