paxilline has been researched along with Cell Transformation, Neoplastic in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (27.59) | 18.2507 |
| 2000's | 14 (48.28) | 29.6817 |
| 2010's | 7 (24.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fujita, Y; Ishikawa, S; Kadeer, A; Kajita, M; Kasai, N; Maruyama, T; Saitoh, S | 1 |
| Al-aidaroos, AQ; Guo, K; Li, J; Liu, H; Wang, H; Zeng, Q; Zhang, HF | 1 |
| Alberghina, L; Baffa, R; Genua, M; Gomella, LG; Iozzo, RV; Lovat, F; Metalli, D; Morrione, A; Spinelli, M; Tripodi, F; Vanoni, M; Xu, SQ | 1 |
| Ahn, KJ; Chang, CH; Jo, YS; Kang, JK; Kang, YJ; Kim, H; Kim, SK; Nam, HJ; Park, SJ; Seok, H; Shong, M | 1 |
| Frame, MC; Lahlou, H; Muller, WJ; Sanguin-Gendreau, V | 1 |
| Chen, SY; Chiu, HY; Jwo, SC; Lee, MY; Sun, GH; Sun, KH; Tang, SJ; Tsou, YC; Wang, HH | 1 |
| Antonyak, MA; Cerione, RA; Yoo, SM | 1 |
| Konger, RL; Ladenson, JH; Landt, Y; Pentland, AP; Scott, GA | 1 |
| Eckman, MS; Jacks, T; Johnson, KC; Kissil, JL; Wilker, EW; Yaffe, MB | 1 |
| Chuang, YC; Huang, CC; Leu, TH; Maa, MC; Su, SL; Yeh, HH | 1 |
| Healy, NC; Huigsloot, M; Kedersha, NL; Kiely, PA; Loughran, G; O'Connor, R | 1 |
| Chang, LC; Chen, BH; Chen, HC; Cheng, CH; Huang, CH | 1 |
| Cocker, R; Fayyad, R; Madan, R; Oktay, MH; Smolkin, MB | 1 |
| Bode, AM; Cho, YY; Dong, Z; He, Z; Mizuno, H; Seok Choi, H; Tatsumi, Y | 1 |
| Baron, S; Cohen, N; Geiger, B; Katz, BZ; Nadav, L; Naparstek, E | 1 |
| Califano, JA; Chang, X; Chatterjee, A; Gollin, SM; Guo, Z; Huang, X; Mambo, E; Moon, C; Osada, M; Ratovitski, EA; Rubin, E; Sidransky, D; Sook Kim, M; Sukumar, S; Trink, B; Wu, F; Wu, G | 1 |
| Han, IO; Hwang, JS; Hwang, SY; Jung, JW; Oh, ES; Park, S | 1 |
| Di Fiore, PP; Romano, A; Santoro, M; Thorgeirsson, SS; Wirth, PJ; Wong, WT | 1 |
| Chan-Hui, PY; Frisch, SM; Ruoslahti, E; Vuori, K | 1 |
| Brazinski, SE; Goldstein, DJ; McCormack, SJ; Moore, JL; Werness, BA | 1 |
| Feltkamp, CA; McCarthy, JB; Meijne, AM; Roos, E; Ruuls-Van Stalle, L | 1 |
| Feller, SM; Kardinal, C; Knudsen, BS; Posern, G; Sakkab, D; Voss, J; Zheng, J | 1 |
| Newell, SW; Perchellet, EM; Perchellet, JP; Ulug, ET | 1 |
| Hung, MC; Lo, SH; Lo, SS; Wang, SC | 1 |
| Chang, JS; Iwashita, S; Kim, MJ; Lee, YH; Ryu, SH; Suh, PG | 1 |
| Morrison, PT; Pisick, E; Salgia, R; Sattler, M | 1 |
| Nakaigawa, N; Schmidt, L; Weirich, G; Zbar, B | 1 |
| Cheng, HY; Rogers, JA; Smithgall, TE | 1 |
| Kamikura, DM; Lamorte, L; Park, M | 1 |
2 review(s) available for paxilline and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Physiological signals and oncogenesis mediated through Crk family adapter proteins.
Topics: Animals; Cell Differentiation; Cell Movement; Cell Transformation, Neoplastic; Chickens; Clonal Anergy; Consensus Sequence; Crk-Associated Substrate Protein; Cytokines; Cytoskeletal Proteins; Enzyme Activation; Fusion Proteins, bcr-abl; Gene Expression Regulation; Growth Substances; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Models, Biological; Multigene Family; Oncogene Protein v-crk; Paxillin; Phosphoproteins; Protein Kinases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-crk; Receptors, Antigen, B-Cell; Receptors, Antigen, T-Cell; Retinoblastoma-Like Protein p130; Retroviridae Proteins, Oncogenic; Signal Transduction; src Homology Domains | 1998 |
Role of the cytoskeletal protein paxillin in oncogenesis.
Topics: Amino Acid Motifs; Animals; Cell Adhesion Molecules; Cell Transformation, Neoplastic; Cytokines; Cytoskeletal Proteins; Humans; Integrins; Neoplasms; Paxillin; Phosphoproteins; Phosphorylation; Receptors, Growth Factor; Signal Transduction | 2000 |
27 other study(ies) available for paxilline and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
The paxillin-plectin-EPLIN complex promotes apical elimination of RasV12-transformed cells by modulating HDAC6-regulated tubulin acetylation.
Topics: Acetylation; Animals; Cell Transformation, Neoplastic; Cytoskeletal Proteins; Dogs; Histone Deacetylase 6; Kidney; Madin Darby Canine Kidney Cells; Mutation; Paxillin; Plectin; Proto-Oncogene Proteins p21(ras); Tubulin; Tubulin Modulators | 2018 |
PRL-3 suppresses c-Fos and integrin α2 expression in ovarian cancer cells.
Topics: Animals; Cell Line, Tumor; Cell Movement; Cell Transformation, Neoplastic; Disease Models, Animal; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Integrin alpha2; Mice; Neoplasm Invasiveness; Neoplasm Proteins; Ovarian Neoplasms; Paxillin; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-fos; Transplantation, Heterologous; Tumor Burden; Up-Regulation | 2013 |
The insulin-like growth factor receptor I promotes motility and invasion of bladder cancer cells through Akt- and mitogen-activated protein kinase-dependent activation of paxillin.
Topics: Cell Line, Tumor; Cell Movement; Cell Transformation, Neoplastic; Focal Adhesion Protein-Tyrosine Kinases; Humans; Mitogen-Activated Protein Kinases; Neoplasm Invasiveness; Paxillin; Proto-Oncogene Proteins c-akt; Receptor, IGF Type 1; RNA, Small Interfering; Signal Transduction; Urinary Bladder Neoplasms | 2010 |
Downregulation of erythropoietin receptor by overexpression of phospholipase C-gamma 1 is critical for decrease on focal adhesion in transformed cells.
Topics: Animals; Cell Adhesion; Cell Movement; Cell Transformation, Neoplastic; Colorectal Neoplasms; Down-Regulation; Erythropoietin; Fibroblasts; Focal Adhesions; Humans; Male; Mice; Middle Aged; Paxillin; PC12 Cells; Phospholipase C gamma; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Rats; Receptors, Erythropoietin; Signal Transduction | 2011 |
Focal adhesion kinase contributes to proliferative potential of ErbB2 mammary tumour cells but is dispensable for ErbB2 mammary tumour induction in vivo.
Topics: Animals; Apoptosis; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Crk-Associated Substrate Protein; Female; Focal Adhesion Kinase 1; Focal Adhesion Kinase 2; Gene Deletion; Integrases; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Neoplasm Transplantation; Paxillin; Phosphorylation; Receptor, ErbB-2; Tumor Burden | 2012 |
Autocrine CCL2 promotes cell migration and invasion via PKC activation and tyrosine phosphorylation of paxillin in bladder cancer cells.
Topics: Animals; Autocrine Communication; Cell Line, Tumor; Cell Movement; Cell Transformation, Neoplastic; Chemokine CCL2; Enzyme Activation; Female; Gene Knockdown Techniques; Humans; Mice; Neoplasm Invasiveness; Paxillin; Phosphorylation; Phosphotyrosine; Protein Kinase C; Receptors, CCR2; Urinary Bladder Neoplasms | 2012 |
The adaptor protein and Arf GTPase-activating protein Cat-1/Git-1 is required for cellular transformation.
Topics: Adaptor Proteins, Signal Transducing; ADP-Ribosylation Factor 6; ADP-Ribosylation Factors; Animals; cdc42 GTP-Binding Protein; Cell Cycle Proteins; Cell Transformation, Neoplastic; Fibroblasts; GTPase-Activating Proteins; HEK293 Cells; HeLa Cells; Humans; Mice; NIH 3T3 Cells; Paxillin; Protein Binding | 2012 |
Loss of the EP2 prostaglandin E2 receptor in immortalized human keratinocytes results in increased invasiveness and decreased paxillin expression.
Topics: Alprostadil; Animals; Antibodies, Monoclonal; Cell Line; Cell Size; Cell Transformation, Neoplastic; Cyclic AMP; Cytoskeletal Proteins; DNA, Antisense; Down-Regulation; Fibroblasts; Genetic Vectors; Humans; Keratinocytes; Paxillin; Phenotype; Phosphoproteins; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Skin | 2002 |
Merlin, the product of the Nf2 tumor suppressor gene, is an inhibitor of the p21-activated kinase, Pak1.
Topics: Animals; Binding Sites; Cell Line, Tumor; Cell Transformation, Neoplastic; Cytoskeletal Proteins; Focal Adhesions; Gene Expression Regulation, Enzymologic; Genes, Neurofibromatosis 2; Humans; Mice; Neurofibromatosis 2; Neurofibromin 2; p21-Activated Kinases; Paxillin; Phosphoproteins; Protein Binding; Protein Serine-Threonine Kinases; rac GTP-Binding Proteins | 2003 |
Participation of p97Eps8 in Src-mediated transformation.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Agar; Animals; Blotting, Northern; Cell Division; Cell Line; Cell Transformation, Neoplastic; Chickens; Cortactin; Cytoskeletal Proteins; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Histones; Hydroxamic Acids; Immunoblotting; Microfilament Proteins; Mutation; Paxillin; Phosphoproteins; Phosphotyrosine; Precipitin Tests; Protein-Tyrosine Kinases; Proteins; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Shc Signaling Adaptor Proteins; Src Homology 2 Domain-Containing, Transforming Protein 1; src-Family Kinases; Time Factors; Transfection | 2004 |
Mystique is a new insulin-like growth factor-I-regulated PDZ-LIM domain protein that promotes cell attachment and migration and suppresses Anchorage-independent growth.
Topics: Actins; Amino Acid Sequence; Animals; Cell Adhesion; Cell Line; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Collagen; Contact Inhibition; Cytoskeletal Proteins; Cytoskeleton; Fibronectins; Gene Silencing; Humans; Insulin-Like Growth Factor I; Integrin beta1; LIM Domain Proteins; Mice; Microfilament Proteins; Molecular Sequence Data; Paxillin; Phosphoproteins; Phosphotyrosine; Protein Isoforms; Protein Structure, Tertiary; Sequence Alignment | 2005 |
Differential effect of the focal adhesion kinase Y397F mutant on v-Src-stimulated cell invasion and tumor growth.
Topics: Actins; Agar; Androstadienes; Animals; Anoikis; Binding Sites; Cell Adhesion; Cell Cycle; Cell Line; Cell Movement; Cell Transformation, Neoplastic; Collagen; Crk-Associated Substrate Protein; Drug Combinations; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Focal Adhesion Protein-Tyrosine Kinases; Focal Adhesions; Gelatin; Genes, Dominant; Immunoblotting; Immunoprecipitation; Laminin; Matrix Metalloproteinase 2; Mice; Mice, Nude; Mice, Transgenic; Microscopy, Fluorescence; Mutation; Neoplasm Invasiveness; Oncogene Protein pp60(v-src); Paxillin; Phosphatidylinositol 3-Kinases; Phosphorylation; Proteoglycans; Proto-Oncogene Proteins c-akt; Signal Transduction; src-Family Kinases; Talin; Time Factors; Transfection; Tyrosine; Vinculin; Wortmannin | 2005 |
Focal adhesion proteins as markers of malignant transformation and prognostic indicators in breast carcinoma.
Topics: Biomarkers, Tumor; Breast; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Intraductal, Noninfiltrating; Cell Transformation, Neoplastic; Female; Fibroadenoma; Focal Adhesion Protein-Tyrosine Kinases; Humans; Immunohistochemistry; Lymph Nodes; Paxillin; Prognosis; Protein Array Analysis; Proto-Oncogene Proteins pp60(c-src); Signal Transduction | 2006 |
Involvement of the paxillin pathway in JB6 Cl41 cell transformation.
Topics: Animals; Base Sequence; Cell Growth Processes; Cell Line; Cell Transformation, Neoplastic; Down-Regulation; Epidermal Growth Factor; MAP Kinase Kinase 4; Mice; Molecular Sequence Data; Paxillin; Phosphorylation; Proto-Oncogene Proteins c-jun; RNA, Small Interfering; Serine; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection | 2006 |
The generation and regulation of functional diversity of malignant plasma cells.
Topics: Cell Adhesion; Cell Line; Cell Line, Tumor; Cell Transformation, Neoplastic; Genetic Variation; Humans; Integrins; Leukemia; Multiple Myeloma; Paxillin; Plasma Cells; Trinucleotide Repeats | 2006 |
Overexpression of glycosylphosphatidylinositol (GPI) transamidase subunits phosphatidylinositol glycan class T and/or GPI anchor attachment 1 induces tumorigenesis and contributes to invasion in human breast cancer.
Topics: Acyltransferases; Breast Neoplasms; Cell Line, Tumor; Cell Transformation, Neoplastic; Cloning, Molecular; Gene Amplification; Gene Dosage; Glycosylphosphatidylinositols; Humans; Membrane Glycoproteins; Neoplasm Invasiveness; Oncogenes; Paxillin; Phosphorylation; Protein Subunits | 2006 |
Ionising radiation induces changes associated with epithelial-mesenchymal transdifferentiation and increased cell motility of A549 lung epithelial cells.
Topics: Actins; Adenocarcinoma; Cell Adhesion; Cell Movement; Cell Transformation, Neoplastic; Epithelial Cells; Focal Adhesion Kinase 1; Humans; Lung Neoplasms; p38 Mitogen-Activated Protein Kinases; Paxillin; Phosphorylation; Radiation, Ionizing; RNA, Messenger; Tumor Cells, Cultured | 2007 |
The high transforming potency of erbB-2 and ret is associated with phosphorylation of paxillin and a 23 kDa protein.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Cell Division; Cell Line, Transformed; Cell Transformation, Neoplastic; Cytoskeletal Proteins; Drosophila Proteins; Electrophoresis, Gel, Two-Dimensional; ErbB Receptors; Mice; Molecular Sequence Data; Paxillin; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret; Receptor Protein-Tyrosine Kinases; Receptor, ErbB-2; Sequence Homology, Amino Acid; Signal Transduction | 1994 |
Control of adhesion-dependent cell survival by focal adhesion kinase.
Topics: Animals; Apoptosis; Calcium-Calmodulin-Dependent Protein Kinases; CD2 Antigens; Cell Adhesion; Cell Adhesion Molecules; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Cytoskeletal Proteins; Dogs; Enzyme Activation; Epithelial Cells; Fibroblasts; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Kidney; Mice; Mice, Nude; Paxillin; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Recombinant Fusion Proteins; Tyrosine | 1996 |
Activation of the focal adhesion kinase signal transduction pathway in cervical carcinoma cell lines and human genital epithelial cells immortalized with human papillomavirus type 18.
Topics: Cell Adhesion Molecules; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Cervix Uteri; Cytoskeletal Proteins; Epithelium; Female; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Genes, src; Humans; Keratinocytes; Papillomaviridae; Paxillin; Phosphoproteins; Phosphorylation; Polymerase Chain Reaction; Protein-Tyrosine Kinases; Signal Transduction; Simian virus 40; Tumor Cells, Cultured; Uterine Cervical Neoplasms | 1997 |
v-src-induced cell shape changes in rat fibroblasts require new gene transcription and precede loss of focal adhesions.
Topics: Actin Cytoskeleton; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Adhesion; Cell Adhesion Molecules; Cell Line, Transformed; Cell Size; Cell Transformation, Neoplastic; Cytoskeletal Proteins; DNA-Binding Proteins; Fibroblasts; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Fusion Proteins, gag-onc; Guanine Nucleotide Exchange Factors; Mutation; Nuclear Proteins; Nucleic Acid Synthesis Inhibitors; Oncogene Protein pp60(v-src); Paxillin; Phosphoproteins; Phosphorylation; Protein Synthesis Inhibitors; Protein-Tyrosine Kinases; Rats; Repressor Proteins; RNA-Binding Proteins; Temperature; Transcription, Genetic; Tyrosine | 1997 |
Alterations in focal adhesion kinase activity and associated proteins during malignant conversion of mouse keratinocytes.
Topics: Animals; Blotting, Western; Calcium; Cell Adhesion Molecules; Cell Differentiation; Cell Line; Cell Line, Transformed; Cell Transformation, Neoplastic; Cytoskeletal Proteins; Enzyme Activation; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Immunohistochemistry; Integrin beta1; Keratinocytes; Mice; Neoplasm Metastasis; Papilloma; Paxillin; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Binding; Protein-Tyrosine Kinases; Skin Neoplasms | 1999 |
Inhibition of focal contact formation in cells transformed by p185neu.
Topics: 3T3 Cells; Animals; Cell Adhesion; Cell Adhesion Molecules; Cell Transformation, Neoplastic; Crk-Associated Substrate Protein; Cytoskeletal Proteins; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Genes, erbB-2; Integrins; Mice; Paxillin; Phosphoproteins; Protein-Tyrosine Kinases; Proteins; Retinoblastoma-Like Protein p130; Signal Transduction; Tyrosine | 1999 |
Transformation of rat fibroblasts by phospholipase C-gamma1 overexpression is accompanied by tyrosine dephosphorylation of paxillin.
Topics: Animals; Cell Adhesion; Cell Size; Cell Transformation, Neoplastic; Cytoskeletal Proteins; Fibroblasts; Fibronectins; Isoenzymes; Paxillin; Phospholipase C gamma; Phosphoproteins; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein Binding; Rats; Type C Phospholipases; Tyrosine | 1999 |
Tumorigenesis mediated by MET mutant M1268T is inhibited by dominant-negative Src.
Topics: 3T3 Cells; Animals; Blood; Cell Division; Cell Transformation, Neoplastic; Cytoskeletal Proteins; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Genes, Dominant; Isoenzymes; Mice; Mitogen-Activated Protein Kinases; Oncogene Protein pp60(v-src); Paxillin; Phospholipase C gamma; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-met; Transfection; Type C Phospholipases | 2000 |
Src homology 2 domain substitution modulates the kinase and transforming activities of the Fes protein-tyrosine kinase.
Topics: Amino Acid Substitution; Animals; Cell Adhesion; Cell Differentiation; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cytoskeletal Proteins; Enzyme Activation; Fibroblasts; Focal Adhesions; Fusion Proteins, gag-onc; Hematopoietic Stem Cells; Humans; Myeloid Cells; Oncogene Protein pp60(v-src); Paxillin; Phosphoproteins; Phosphorylation; Protein Transport; Protein-Tyrosine Kinases; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fes; ras GTPase-Activating Proteins; Rats; Recombinant Fusion Proteins; src Homology Domains | 2000 |
A switch from p130Cas/Crk to Gab1/Crk signaling correlates with anchorage independent growth and JNK activation in cells transformed by the Met receptor oncoprotein.
Topics: 3T3 Cells; Actins; Adaptor Proteins, Signal Transducing; Animals; Cell Adhesion; Cell Division; Cell Size; Cell Transformation, Neoplastic; Crk-Associated Substrate Protein; Cytoskeletal Proteins; Enzyme Activation; Fibronectins; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Focal Adhesions; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mice; Mitogen-Activated Protein Kinase Kinases; Mutation; Oncogene Proteins; Paxillin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Binding; Protein-Tyrosine Kinases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-crk; Proto-Oncogene Proteins c-met; Retinoblastoma-Like Protein p130; Signal Transduction; Stress Fibers; Wound Healing | 2000 |