paxilline has been researched along with Breast Cancer in 77 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (10.39) | 18.2507 |
| 2000's | 24 (31.17) | 29.6817 |
| 2010's | 39 (50.65) | 24.3611 |
| 2020's | 6 (7.79) | 2.80 |
| Authors | Studies |
|---|---|
| Alpha, KM; Turner, CE; Xu, W; Zehrbach, NM | 1 |
| Khan, A; Shan, S; Suleman, M; Toor, TF; Wang, Y; Wei, DQ; Zhou, J | 1 |
| Hu, T; Huang, C; Jiang, W; Kundu, M; Liang, P; Ma, S; Wang, B; Wang, J; Wu, Y; Xiao, L; Xing, Q; Xu, Z; Yang, S; Zhang, J; Zheng, S | 1 |
| Kishi, H; Kobayashi, S; Maeda, N; Nagano, H; Tsunedomi, R; Xu, M; Zhang, Y; Zheng, H | 1 |
| Chang, TT; Chen, CL; Chen, WS; Fu, CW; Hsiao, PW; Li, WS; Tsai, HE | 1 |
| Ahnlide, JK; Axelson, H; Englund, E; Kanzaki, R; Kjellman, P; Li, Z; Lindgren, D; Madsen, CD; Pietras, K; Prinz, CN; Rodriguez-Cupello, C; Saggioro, M; Swaminathan, V; Wang, S | 1 |
| Bednarczyk-Cwynar, B; Lisiak, N; Pakuła, M; Paszel-Jaworska, A; Rubiś, B; Rybczyńska, M; Totoń, E; Zaprutko, L | 1 |
| Barnes, JM; Bell, ES; Cassereau, L; Chang, AC; Davidson, MW; DuFort, CC; Dunn, AR; Kai, F; Lakins, JN; Lammerding, J; McGregor, AL; Mekhdjian, AH; Odde, DJ; Ou, G; Pickup, MW; Prahl, LS; Przybyla, LM; Rubashkin, MG; Tan, SJ; Weaver, VM; Ye, X | 1 |
| Alaoui-Jamali, MA; Bijian, K; Chang, CH; Dahabieh, MS; Miller, WH; Qiu, D; Saad, A; Su, J | 1 |
| Li, BH; Yuan, L | 1 |
| Jiang, WG; Mason, MD; Sanders, AJ; Sobkowicz, AD | 1 |
| Ding, J; Fu, XH; Geng, MY; Huang, X; Sun, DN; Wei, RR; Yan, J; Yang, H; Zhang, X; Zheng, XL | 1 |
| Chen, XP; Lu, JJ; Luo, WW; Wang, YT; Zhao, WW | 1 |
| Brüne, B; Ebersberger, I; Ebersberger, S; Fink, AF; Frank, AC; Lampe, S; Schmid, T; Syed, SN; Weigert, A | 1 |
| Atanasov, AG; de Martin, R; Diederich, M; Dirsch, VM; Dolznig, H; Giessrigl, B; Grusch, M; Huttary, N; Jäger, W; Jarukamjorn, K; Kopf, S; Kretschy, N; Krieger, S; Krupitza, G; Mikulits, W; Raab, I; Rarova, L; Saiko, P; Schumacher, M; Strnad, M; Szekeres, T; Teichmann, M; Viola, K; Vonach, C | 1 |
| Kandelman, JD; Smith, RL; Szejnfeld, J; Waitzberg, AF | 1 |
| Díaz, J; Leyton, L; Mendoza, P; Ortiz, R; Quest, AF; Stupack, D; Torres, VA | 1 |
| Chang, LS; Chiu, CC; Chu, CL; Lin, SR; Tsai, PC | 1 |
| Chen, XP; Guo, JJ; Lu, JJ; Song, YL; Wang, SP; Wang, YT; Wu, GS; Yin, ZQ; Zhang, QW; Zhao, WW | 1 |
| Akl, MR; El Sayed, KA; Foudah, AI; Liu, YY; Meyer, SA; Mohyeldin, MM; Nazzal, S; Sallam, AA | 1 |
| Akl, MR; Ebrahim, HY; El Sayed, KA; Elsayed, HE; Haggag, EG; Kamal, AM; Sallam, AA | 1 |
| Hammes, SR; Miedlich, SU; Sen, A | 1 |
| Ameka, M; Cuevas, BD; Gentile, S; Kahle, MP; Mirza, AA; Perez-Neut, M | 1 |
| De Las Casas, LE; Diakonova, M; Hammer, A; Oladimeji, P | 1 |
| Claing, A; Ramirez, RA; Schlienger, S | 1 |
| Ackerman, WE; Blackstone, BN; Ghadiali, SN; Kniss, DA; Li, R; Powell, HM | 1 |
| Feldmann, P; Heintzmann, R; Jost, A; Sentenac, A; Tolstik, E; Wicker, K | 1 |
| Al Sheeha, M; Omran, OM | 1 |
| Chang, FR; Chen, IH; Hsieh, PW; Shih, HC; Wu, CC; Wu, YC | 1 |
| Davidson, D; Li, J; Martins Souza, C; Muller, WJ; Park, M; Veillette, A; Wu, N; Zhong, MC | 1 |
| Hill, A; McFarlane, C; McFarlane, S; Montgomery, N; Waugh, DJ | 1 |
| Hu, XJ; Li, Y; Liu, CM; Xiong, XY | 1 |
| Flamini, MI; Neira, FJ; Sanchez, AM; Shortrede, JE; Uzair, ID | 1 |
| Flamini, MI; Sanchez, AM; Shortrede, JE; Vargas-Roig, LM | 1 |
| Carvalho, C; Lucas, J; West, M | 1 |
| Chan, KT; Cortesio, CL; Huttenlocher, A | 1 |
| Dong, Z; Huang, S; Li, Y; Luo, Y; Padia, RN; Pan, ZK; Sheng, Y; Su, S; Su, Y | 1 |
| Entschladen, F; Lang, K; Niggemann, B; Strell, C; Zaenker, KS | 1 |
| Cai, H; Li, SL; Tang, WX; Zhang, T | 1 |
| Chen, CC; Chen, PH; Pai, HC; Peng, CY; Teng, CM; Yang, CR | 1 |
| Deakin, NO; Turner, CE | 1 |
| Athanassiadou, AM; Athanassiadou, P; Kyriakidou, V; Lagoudianakis, E; Manouras, A; Panousis, D; Pappas, A; Patsouris, E; Voulgaris, Z; Xepapadakis, G | 1 |
| Allgayer, H; Baumann, P; Cremers, N; Diefenbacher, M; Frame, M; Kassel, O; Krachulec, J; Mudduluru, G; Muppala, S; Sleeman, JP; Thiele, W | 1 |
| Jiang, WG; Li, J; Sanders, AJ; Ye, L | 1 |
| Chang, CH; Chang, HW; Chen, CS; Chen, LC; Ho, CT; Ho, YS; Huang, CS; Lee, CH; Lee, WS; Lin, HW; Tu, SH; Wu, CH | 1 |
| Calcabrini, A; Gómez-Domínguez, D; Gómez-López, G; Martín-Forero, E; Martín-Pérez, J; Molinari, A; Morte, B; Sánchez-Bailón, MP; Wagner, KU | 1 |
| Chen, J; Gallo, KA | 1 |
| Bose, R; Boyer, AP; Collier, TS; Vidavsky, I | 1 |
| Garvalov, BK; Griffiths, G; Higgins, TE; Köcher, T; Piddini, E; Scaplehorn, N; Sutherland, JD; Way, M; Zettl, M | 1 |
| Davies, G; Jiang, WG; Lane, J; Mansel, RE; Martin, TA; Matsumoto, K; Nakamura, T; Parr, C; Watkins, G | 1 |
| Cance, WG; Craven, RJ; Golubovskaya, V; Lee, JW; Park, HB; Scully, S; Xu, L; Yang, X | 1 |
| Avraham, HK; Avraham, S; Fu, Y; Jiang, S; Zrihan-Licht, S | 1 |
| Bokoch, GM; Gardiner, EM; Sanders, LC; Stofega, MR | 1 |
| Adachi, M; Hashimoto, A; Hashimoto, S; Manabe, T; Matsuura, N; Mazaki, Y; Morishige, M; Ogawa, E; Onodera, Y; Sabe, H; Sakurai, T; Wada, H; Yamada, A | 1 |
| Barrow, D; Gee, J; Green, TP; Hiscox, S; Morgan, L; Nicholson, RI | 1 |
| Cocker, R; Fayyad, R; Madan, R; Oktay, MH; Smolkin, MB | 1 |
| Hashimoto, S; Onodera, Y | 1 |
| Doong, H; Guancial, EA; Kassis, JN; Kohn, EC; Virador, V | 1 |
| Califano, JA; Chang, X; Chatterjee, A; Gollin, SM; Guo, Z; Huang, X; Mambo, E; Moon, C; Osada, M; Ratovitski, EA; Rubin, E; Sidransky, D; Sook Kim, M; Sukumar, S; Trink, B; Wu, F; Wu, G | 1 |
| Antico, G; Clevenger, CV; Miller, SL; Raghunath, PN; Tomaszewski, JE | 1 |
| Babu, MS; Cha, ST; Chang, KJ; Chen, CN; Chen, MW; Chen, PS; Chuang, SE; Hong, CC; Hua, KT; Kuo, ML; Lee, PH; Su, JL; Wang, MY; Wu, SN; Wu, YL | 1 |
| Boyce, T; Clack, G; Duffield, E; Fennell, M; Green, T; Jacobs, V; Jones, RJ; Kelly, J; Pinto, F; Robertson, J | 1 |
| Jove, R; Rivera, M; Scuto, A; Torres-Roca, JF; Yeatman, TJ; Zhang, H; Zhao, H | 1 |
| Anderson, GM; Chen, Q; Doshi, P; Ferrante, C; Manning, CD; McCabe, FL; Millar, H; Nakada, MT; Shahied-Arruda, L; Sharp, C | 1 |
| Donahue, HJ; Li, Z; Zhou, Z | 1 |
| Clack, G; Dixon, JM; Elvin, P; Fennell, M; Green, TP; Jacobs, V; Jones, RJ; Marshall, A; Renshaw, L; Womack, C; Young, O | 1 |
| Canbay, E; Goffin, V; Kilic, E; Norman, M; Zachary, I | 1 |
| Bartholomew, PJ; DePasquale, JA; Vinci, JM | 1 |
| Amin, S; Chandraratna, RA; De Luca, LM; Haque, M; Jones, CS; Matsukuma, K; Vuligonda, V; Zhu, WY | 1 |
| Nohara, K; Olivera, A; Spiegel, S; Thompson, EW; Wang, F | 1 |
| Adam, L; Costa, L; Kumar, R; Tseng, B; Vadlamudi, R | 1 |
| Guvakova, MA; Surmacz, E | 1 |
| Barth, M; Bowden, ET; Glazer, RI; Mueller, SC; Thomas, D | 1 |
| Adam, L; Kumar, R; Mendelsohn, J; Talukder, A; Vadlamudi, R | 1 |
| Aw, SE; Bay, BH; Lin, VC; Ng, EH; Tan, MG | 1 |
| Kang, MS; Lee, KH; Lee, YJ; Song, SH | 1 |
| Avraham, H; Avraham, S; Fu, Y; McShan, GD; Park, SY; Zagozdzon, R; Zrihan-Licht, S | 1 |
1 review(s) available for paxilline and Breast Cancer
| Article | Year |
|---|---|
[Breast cancer invasiveness: how does it emerge?].
Topics: Adaptor Proteins, Signal Transducing; ADP-Ribosylation Factor 6; ADP-Ribosylation Factors; Animals; Breast Neoplasms; Cadherins; Cell Adhesion; Female; Humans; Hypoxia-Inducible Factor 1; Integrins; Neoplasm Invasiveness; Neovascularization, Pathologic; Paxillin; Protein Binding; Transcription, Genetic | 2006 |
76 other study(ies) available for paxilline and Breast Cancer
| Article | Year |
|---|---|
Paxillin promotes breast tumor collective cell invasion through maintenance of adherens junction integrity.
Topics: Adherens Junctions; Animals; Breast; Breast Neoplasms; Cadherins; Cell Adhesion; Cell Line, Tumor; Cell Movement; Epithelial Cells; Female; Focal Adhesions; Mice; Mice, Inbred C57BL; Mice, Knockout; Neoplasm Invasiveness; Paxillin; rho GTP-Binding Proteins | 2022 |
Repositioning of experimentally validated anti-breast cancer peptides to target FAK-PAX complex to halt the breast cancer progression: a biomolecular simulation approach.
Topics: Breast Neoplasms; Drug Repositioning; Female; Humans; Magainins; Molecular Docking Simulation; Molecular Dynamics Simulation; Paxillin; Protein-Tyrosine Kinases | 2023 |
An ULK1/2-PXN mechanotransduction pathway suppresses breast cancer cell migration.
Topics: Autophagy-Related Protein-1 Homolog; Breast Neoplasms; Cell Movement; Female; Humans; Intracellular Signaling Peptides and Proteins; Mechanotransduction, Cellular; Paxillin; Phosphorylation; Serine | 2023 |
Fyn-Mediated Paxillin Tyrosine 31 Phosphorylation Regulates Migration and Invasion of Breast Cancer Cells.
Topics: Breast Neoplasms; Cell Movement; Female; Humans; Paxillin; Phosphorylation; Tyrosine | 2023 |
Sialyltransferase Inhibitors Suppress Breast Cancer Metastasis.
Topics: Animals; Animals, Genetically Modified; Breast Neoplasms; Catalysis; Cell Line, Tumor; Enzyme Inhibitors; Female; Focal Adhesion Protein-Tyrosine Kinases; Glycoproteins; Humans; Integrins; Isoenzymes; Molecular Docking Simulation; Neoplasm Metastasis; NF-kappa B; Paxillin; Phosphorylation; Sialyltransferases; Signal Transduction; Talin; Zebrafish | 2021 |
CCM3 is a gatekeeper in focal adhesions regulating mechanotransduction and YAP/TAZ signalling.
Topics: Adaptor Proteins, Signal Transducing; Animals; Apoptosis Regulatory Proteins; Breast Neoplasms; Cancer-Associated Fibroblasts; Cell Communication; Cell Differentiation; Cell Line, Tumor; Female; Focal Adhesion Kinase 1; Focal Adhesions; Gene Expression Regulation, Neoplastic; Humans; Intracellular Signaling Peptides and Proteins; Mechanotransduction, Cellular; Membrane Proteins; Mesenchymal Stem Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Paxillin; Phosphorylation; Protein Binding; Proto-Oncogene Proteins; src-Family Kinases; Stress, Mechanical; Transcription Factors; Transcriptional Coactivator with PDZ-Binding Motif Proteins; YAP-Signaling Proteins | 2021 |
Semisynthetic oleanane triterpenoids inhibit migration and invasion of human breast cancer cells through downregulated expression of the ITGB1/PTK2/PXN pathway.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Down-Regulation; Focal Adhesion Kinase 1; Humans; Integrin beta1; Neoplasm Invasiveness; Oleanolic Acid; Paxillin; Signal Transduction | 2017 |
Integrin-mediated traction force enhances paxillin molecular associations and adhesion dynamics that increase the invasiveness of tumor cells into a three-dimensional extracellular matrix.
Topics: Breast; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Extracellular Matrix; Female; Focal Adhesion Protein-Tyrosine Kinases; Humans; Integrins; Neoplasm Metastasis; Paxillin; Phosphorylation; Signal Transduction | 2017 |
Endosomal sorting and c-Cbl targeting of paxillin to autophagosomes regulate cell-matrix adhesion turnover in human breast cancer cells.
Topics: Autophagosomes; Autophagy; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Disease Progression; Endosomes; Extracellular Matrix; Gene Knockdown Techniques; Humans; Microtubule-Associated Proteins; Neoplasm Metastasis; Paxillin; Phosphorylation; Protein Binding; Proteolysis; Proto-Oncogene Proteins c-cbl; rab GTP-Binding Proteins; rab7 GTP-Binding Proteins; Signal Transduction | 2017 |
[Inhibitory effects of capsaicin on migration and invasion of breast cancer MDA-MB-231 cells and its mechanism].
Topics: Breast Neoplasms; Capsaicin; Cell Line, Tumor; Cell Movement; CSK Tyrosine-Protein Kinase; Down-Regulation; Focal Adhesion Kinase 1; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Paxillin; Phosphorylation; src-Family Kinases | 2017 |
Potential Implication of Paxillin in Cancer Establishment Within the Bone Environment.
Topics: Bone Matrix; Bone Neoplasms; Breast Neoplasms; Cell Extracts; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Hepatocyte Growth Factor; Humans; Male; Neoplasm Invasiveness; Paxillin; Prostatic Neoplasms | 2017 |
CTC clusters induced by heparanase enhance breast cancer metastasis.
Topics: Animals; Breast Neoplasms; Cell Adhesion; Cell Aggregation; Cell Line, Tumor; Female; Focal Adhesion Kinase 1; Glucuronidase; Humans; Intercellular Adhesion Molecule-1; Mice, Inbred BALB C; Neoplasm Metastasis; Neoplastic Cells, Circulating; Paxillin; src-Family Kinases; Up-Regulation | 2018 |
Cucurbitacin B suppresses metastasis mediated by reactive oxygen species (ROS) via focal adhesion kinase (FAK) in breast cancer MDA-MB-231 cells.
Topics: Acetylcysteine; Antineoplastic Agents; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Collagen Type I; Dose-Response Relationship, Drug; Down-Regulation; Female; Fibronectins; Focal Adhesion Kinase 1; Humans; Neoplasm Invasiveness; Neoplasm Metastasis; Paxillin; Phosphorylation; Reactive Oxygen Species; Triterpenes | 2018 |
Apoptotic tumor cell-derived microRNA-375 uses CD36 to alter the tumor-associated macrophage phenotype.
Topics: Animals; Apoptosis; Breast Neoplasms; CD36 Antigens; Cell Movement; Chemokine CCL2; Coculture Techniques; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Macrophages; MCF-7 Cells; Mice; Mice, Nude; MicroRNAs; Paxillin; Phenotype; Signal Transduction; Spheroids, Cellular; Tensins; Tumor Burden; Tumor Microenvironment; Xenograft Model Antitumor Assays | 2019 |
In vitro characterisation of the anti-intravasative properties of the marine product heteronemin.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Blotting, Western; Breast Neoplasms; Cell Movement; Coculture Techniques; Cytochrome P-450 CYP1A1; Endothelial Cells; Female; Humans; Lymphatic Metastasis; MCF-7 Cells; NF-kappa B; Paxillin; Terpenes | 2013 |
Expression of claudin, paxillin and FRA-1 in non-nodular breast lesions in association with microcalcifications.
Topics: Antibodies, Monoclonal; Biomarkers, Tumor; Breast; Breast Neoplasms; Calcinosis; Claudins; Epidemiologic Methods; Female; Humans; Hyperplasia; Paxillin; Precancerous Conditions; Proto-Oncogene Proteins c-fos; Receptor, ErbB-2 | 2013 |
Rab5 activation promotes focal adhesion disassembly, migration and invasiveness in tumor cells.
Topics: Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Enzyme Activation; Female; Focal Adhesions; Humans; Lung Neoplasms; Neoplasm Invasiveness; Neoplasm Metastasis; Paxillin; rab5 GTP-Binding Proteins; RNA Interference; RNA, Small Interfering; Vinculin | 2013 |
Inhibition of Src activation with cardiotoxin III blocks migration and invasion of MDA-MB-231 cells.
Topics: Apoptosis; Breast Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cobra Cardiotoxin Proteins; Female; Focal Adhesion Protein-Tyrosine Kinases; Humans; MAP Kinase Signaling System; Matrix Metalloproteinase 9; Paxillin; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; src-Family Kinases | 2013 |
Ganoderiol A-enriched extract suppresses migration and adhesion of MDA-MB-231 cells by inhibiting FAK-SRC-paxillin cascade pathway.
Topics: Actins; Apoptosis; Breast Neoplasms; Cell Adhesion; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Female; Focal Adhesion Protein-Tyrosine Kinases; Humans; Paxillin; Phosphorylation; Polysaccharides; Protein Binding; rho GTP-Binding Proteins; Signal Transduction; src-Family Kinases | 2013 |
Marine natural products-inspired phenylmethylene hydantoins with potent in vitro and in vivo antitumor activities via suppression of Brk and FAK signaling.
Topics: Animals; Antineoplastic Agents; Benzaldehydes; Biological Products; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Female; Focal Adhesion Kinase 1; Gene Expression Regulation, Neoplastic; Humans; Hydantoins; Male; Mice; Mice, Nude; Mice, Transgenic; Neoplasm Proteins; Paxillin; Prostate; Protein-Tyrosine Kinases; rac1 GTP-Binding Protein; Receptor Protein-Tyrosine Kinases; Signal Transduction; Xenograft Model Antitumor Assays | 2014 |
Discovery, optimization, and pharmacophore modeling of oleanolic acid and analogues as breast cancer cell migration and invasion inhibitors through targeting Brk/Paxillin/Rac1 axis.
Topics: Antineoplastic Agents, Phytogenic; Breast; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Drug Discovery; Female; Humans; Models, Molecular; Neoplasm Invasiveness; Neoplasm Proteins; Oleanolic Acid; Paxillin; Protein-Tyrosine Kinases; rac1 GTP-Binding Protein; Signal Transduction; Terminalia | 2015 |
Paxillin and steroid signaling: from frog to human.
Topics: Animals; Anura; Breast Neoplasms; Female; Germ Cells; Humans; Intercellular Signaling Peptides and Proteins; Male; Meiosis; Neoplasms; Paxillin; Prostatic Neoplasms; Signal Transduction; Steroids | 2014 |
MEKK2 regulates paxillin ubiquitylation and localization in MDA-MB 231 breast cancer cells.
Topics: Breast Neoplasms; Cell Line, Tumor; Female; HEK293 Cells; Humans; MAP Kinase Kinase Kinase 2; MAP Kinase Kinase Kinases; MCF-7 Cells; Paxillin; Ubiquitination | 2014 |
Phosphorylation of tyrosine 285 of PAK1 facilitates βPIX/GIT1 binding and adhesion turnover.
Topics: Adaptor Proteins, Signal Transducing; Blotting, Western; Breast Neoplasms; Cell Adhesion; Cell Cycle Proteins; Cell Movement; Cell Proliferation; Female; Fluorescent Antibody Technique; Humans; Immunoenzyme Techniques; Immunoprecipitation; p21-Activated Kinases; Paxillin; Phosphorylation; Protein Binding; Rho Guanine Nucleotide Exchange Factors; Signal Transduction; Tumor Cells, Cultured; Tyrosine | 2015 |
ARF1 regulates adhesion of MDA-MB-231 invasive breast cancer cells through formation of focal adhesions.
Topics: ADP-Ribosylation Factor 1; Aniline Compounds; Benzimidazoles; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Epidermal Growth Factor; Female; Focal Adhesion Kinase 1; Focal Adhesions; Gene Expression Regulation; Humans; Integrin beta1; Paxillin; Phosphorylation; Protein Binding; RNA Interference; RNA, Small Interfering; Talin | 2015 |
Myoferlin depletion elevates focal adhesion kinase and paxillin phosphorylation and enhances cell-matrix adhesion in breast cancer cells.
Topics: Breast Neoplasms; Calcium-Binding Proteins; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell-Matrix Junctions; Extracellular Matrix; Female; Focal Adhesion Protein-Tyrosine Kinases; Focal Adhesions; Humans; MCF-7 Cells; Membrane Proteins; Muscle Proteins; Neoplasm Invasiveness; Paxillin; Phosphorylation; RNA Interference; RNA, Small Interfering | 2015 |
Optical Sectioning and High Resolution in Single-Slice Structured Illumination Microscopy by Thick Slice Blind-SIM Reconstruction.
Topics: Actins; Algorithms; Artifacts; Breast Neoplasms; Cell Line, Tumor; Female; Humans; Lighting; Microscopy, Fluorescence; Optical Imaging; Paxillin | 2015 |
Cytoskeletal Focal Adhesion Proteins Fascin-1 and Paxillin Are Predictors of Malignant Progression and Poor Prognosis in Human Breast Cancer.
Topics: Adult; Biomarkers, Tumor; Breast Neoplasms; Carrier Proteins; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Microfilament Proteins; Middle Aged; Paxillin; Prognosis | 2015 |
HPW-RX40 restores anoikis sensitivity of human breast cancer cells by inhibiting integrin/FAK signaling.
Topics: Anoikis; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis Regulatory Proteins; Breast Neoplasms; Cell Adhesion; Cell Aggregation; Cell Line, Tumor; Chlorobenzoates; Dose-Response Relationship, Drug; Enzyme Activation; ErbB Receptors; Female; Focal Adhesion Kinase 1; Humans; Integrin beta1; Paxillin; Phosphorylation; Protein Kinase Inhibitors; Quinazolines; Signal Transduction; src-Family Kinases; Styrenes; Tyrphostins | 2015 |
Loss of PTPN12 Stimulates Progression of ErbB2-Dependent Breast Cancer by Enhancing Cell Survival, Migration, and Epithelial-to-Mesenchymal Transition.
Topics: Animals; Anoikis; Breast; Breast Neoplasms; Cell Movement; Cell Survival; Epithelial-Mesenchymal Transition; Female; Focal Adhesion Kinase 2; Gene Deletion; Gene Knockout Techniques; Humans; Mice; Neoplasm Invasiveness; Paxillin; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 12; Receptor, ErbB-2; Tumor Cells, Cultured | 2015 |
CD44-mediated activation of α5β1-integrin, cortactin and paxillin signaling underpins adhesion of basal-like breast cancer cells to endothelium and fibronectin-enriched matrices.
Topics: Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cortactin; Female; Fibronectins; Humans; Hyaluronan Receptors; Integrin alpha5beta1; Paxillin; Signal Transduction | 2015 |
Inhibitory Effects of Enterolactone on Growth and Metastasis in Human Breast Cancer.
Topics: 4-Butyrolactone; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclins; Cytoskeleton; Focal Adhesion Kinase 1; Forkhead Box Protein M1; Forkhead Transcription Factors; Gene Expression; Humans; Ki-67 Antigen; Lignans; Neoplasm Invasiveness; Neoplasm Metastasis; Paxillin; Proliferating Cell Nuclear Antigen; RNA, Messenger; S Phase; Signal Transduction | 2015 |
Paxillin, a novel controller in the signaling of estrogen to FAK/N-WASP/Arp2/3 complex in breast cancer cells.
Topics: Actin Cytoskeleton; Actin-Related Protein 2-3 Complex; Breast Neoplasms; cdc42 GTP-Binding Protein; Cell Adhesion; Cell Line, Tumor; Cell Movement; Estrogen Receptor alpha; Estrogens; Female; Focal Adhesion Protein-Tyrosine Kinases; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein beta Subunits; Humans; Neoplasm Invasiveness; Paxillin; Phosphorylation; Protein Transport; Raloxifene Hydrochloride; Signal Transduction; src-Family Kinases; Wiskott-Aldrich Syndrome Protein, Neuronal | 2016 |
Retinoic acid induces nuclear FAK translocation and reduces breast cancer cell adhesion through Moesin, FAK, and Paxillin.
Topics: Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Nucleus; Female; Focal Adhesion Protein-Tyrosine Kinases; HSP27 Heat-Shock Proteins; HSP72 Heat-Shock Proteins; Humans; Microfilament Proteins; Paxillin; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Transport; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Signal Transduction; src-Family Kinases; Tretinoin; Tumor Suppressor Protein p53 | 2016 |
A bayesian analysis strategy for cross-study translation of gene expression biomarkers.
Topics: Bayes Theorem; Biomarkers; Breast Neoplasms; Comparative Genomic Hybridization; Female; Gene Dosage; Gene Expression Profiling; Genome-Wide Association Study; Humans; Models, Genetic; Normal Distribution; Paxillin; Proto-Oncogene Proteins c-myc; Regression Analysis; Survival Analysis; Vinculin | 2009 |
FAK alters invadopodia and focal adhesion composition and dynamics to regulate breast cancer invasion.
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Surface Extensions; Female; Focal Adhesion Protein-Tyrosine Kinases; Focal Adhesions; Humans; Neoplasm Invasiveness; Paxillin; Recombinant Fusion Proteins; RNA, Small Interfering; src-Family Kinases; Tyrosine | 2009 |
Proteinase-activated receptor 2 expression in breast cancer and its role in breast cancer cell migration.
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Movement; Chemotaxis; CSK Tyrosine-Protein Kinase; Female; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; JNK Mitogen-Activated Protein Kinases; Paxillin; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Receptor, PAR-2; Signal Transduction; src-Family Kinases; Trypsin | 2009 |
Neutrophil granulocytes promote the migratory activity of MDA-MB-468 human breast carcinoma cells via ICAM-1.
Topics: Antibodies, Monoclonal; Breast Neoplasms; Calcium Signaling; Cell Communication; Cell Line, Tumor; Cell Movement; Chemokine CXCL1; Coculture Techniques; Cross-Linking Reagents; Culture Media, Conditioned; Estrenes; Female; Focal Adhesion Kinase 1; Humans; Intercellular Adhesion Molecule-1; Interleukin-8; Macrophage-1 Antigen; Neutrophils; p38 Mitogen-Activated Protein Kinases; Paxillin; Phosphorylation; Protein Kinase C; Protein Kinase Inhibitors; Pyrimidines; Pyrrolidinones; rho-Associated Kinases; RNA, Small Interfering; Signal Transduction; src-Family Kinases; Thapsigargin | 2010 |
[Expression of paxillin in breast cancer cell with high and low metastatic potentiality].
Topics: Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Female; Humans; Neoplasm Metastasis; Paxillin | 2010 |
Denbinobin suppresses breast cancer metastasis through the inhibition of Src-mediated signaling pathways.
Topics: Animals; Anthraquinones; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; Crk-Associated Substrate Protein; Female; Focal Adhesion Kinase 1; Humans; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Paxillin; Phenanthrenes; Phosphorylation; Signal Transduction; src-Family Kinases; Transfection | 2011 |
Distinct roles for paxillin and Hic-5 in regulating breast cancer cell morphology, invasion, and metastasis.
Topics: Animals; Breast Neoplasms; Cattle; Cell Adhesion; Cell Line, Tumor; Cell Movement; Extracellular Matrix; Female; Humans; Intracellular Signaling Peptides and Proteins; LIM Domain Proteins; Lung Neoplasms; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Invasiveness; Neoplasm Metastasis; Paxillin; rhoA GTP-Binding Protein; Signal Transduction | 2011 |
The value of TOP2A, EZH2 and paxillin expression as markers of aggressive breast cancer: relationship with other prognostic factors.
Topics: Adult; Aged; Antigens, Neoplasm; Biomarkers, Tumor; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; DNA Topoisomerases, Type II; DNA-Binding Proteins; Enhancer of Zeste Homolog 2 Protein; Female; Humans; Immunohistochemistry; Middle Aged; Paxillin; Poly-ADP-Ribose Binding Proteins; Polycomb Repressive Complex 2; Prognosis; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Transcription Factors | 2011 |
CD24 interacts with and promotes the activity of c-src within lipid rafts in breast cancer cells, thereby increasing integrin-dependent adhesion.
Topics: Anti-Bacterial Agents; Breast Neoplasms; CD24 Antigen; Cell Adhesion; Cell Line, Tumor; Cell Movement; CSK Tyrosine-Protein Kinase; Doxycycline; Female; Fibronectins; Focal Adhesion Kinase 1; Humans; Integrins; Membrane Microdomains; Paxillin; Phosphorylation; Protein Binding; Protein-Tyrosine Kinases; Pyrimidines; src-Family Kinases | 2012 |
Repulsive guidance molecule B (RGMB) plays negative roles in breast cancer by coordinating BMP signaling.
Topics: Apoptosis; Bone Morphogenetic Proteins; Breast Neoplasms; Caspase 3; Cell Adhesion; Cell Adhesion Molecules, Neuronal; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Female; Focal Adhesion Kinase 1; Focal Adhesions; Gene Knockdown Techniques; Humans; JNK Mitogen-Activated Protein Kinases; Nuclear Proteins; Paxillin; Signal Transduction; Smad Proteins; Snail Family Transcription Factors; Transcription Factors; Twist-Related Protein 1 | 2012 |
Human breast cancer cell metastasis is attenuated by lysyl oxidase inhibitors through down-regulation of focal adhesion kinase and the paxillin-signaling pathway.
Topics: Adult; Aged; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Down-Regulation; Enzyme Inhibitors; Female; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression; Humans; Hydrogen Peroxide; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Paxillin; Prognosis; Protein-Lysine 6-Oxidase; RNA, Messenger; Signal Transduction; src-Family Kinases | 2012 |
Src kinases catalytic activity regulates proliferation, migration and invasiveness of MDA-MB-231 breast cancer cells.
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dasatinib; Female; Humans; Indoles; Neoplasm Invasiveness; Paxillin; Protein Kinase Inhibitors; Pyrimidines; src-Family Kinases; Sulfonamides; Thiazoles | 2012 |
MLK3 regulates paxillin phosphorylation in chemokine-mediated breast cancer cell migration and invasion to drive metastasis.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Chemokine CXCL12; Female; Humans; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Mice; Mice, Nude; Mitogen-Activated Protein Kinase Kinase Kinase 11; Neoplasm Invasiveness; Paxillin; Phosphorylation | 2012 |
Quantitative proteomics with siRNA screening identifies novel mechanisms of trastuzumab resistance in HER2 amplified breast cancers.
Topics: Antibodies, Monoclonal, Humanized; Antigens, CD; Antigens, Neoplasm; Breast Neoplasms; Cell Adhesion Molecules; Cell Line, Tumor; Cyclin-Dependent Kinases; Drug Resistance, Neoplasm; Female; Humans; Isotope Labeling; Neoplasm Proteins; Paxillin; Phosphatidylinositol 3-Kinase; Phosphorylation; Phosphotyrosine; Proteomics; Proto-Oncogene Proteins c-akt; Receptor, ErbB-2; RNA Interference; RNA, Small Interfering; Signal Transduction; Trastuzumab | 2013 |
The conformational state of Tes regulates its zyxin-dependent recruitment to focal adhesions.
Topics: Actinin; Breast Neoplasms; Carcinoma; Carrier Proteins; Cell Adhesion; Cell Adhesion Molecules; Cell Division; Cytoskeletal Proteins; Eukaryotic Cells; Female; Focal Adhesions; Genes, Tumor Suppressor; Glycoproteins; Green Fluorescent Proteins; HeLa Cells; Homeodomain Proteins; Humans; LIM Domain Proteins; Luminescent Proteins; Metalloproteins; Microfilament Proteins; Molecular Conformation; Paxillin; Phosphoproteins; Protein Structure, Tertiary; Protein Transport; Recombinant Fusion Proteins; RNA-Binding Proteins; Stress Fibers; Tumor Suppressor Proteins; Vinculin; Zyxin | 2003 |
Growth and angiogenesis of human breast cancer in a nude mouse tumour model is reduced by NK4, a HGF/SF antagonist.
Topics: Animals; Blotting, Western; Breast Neoplasms; Cell Adhesion; Cell Division; Cell Movement; Cytoskeletal Proteins; Disease Models, Animal; Female; Fibroblasts; Gene Expression Regulation, Neoplastic; Hepatocyte Growth Factor; Humans; Mice; Mice, Nude; Mitogens; Neoplasm Invasiveness; Neovascularization, Pathologic; Paxillin; Phosphoproteins; Phosphorylation; Proto-Oncogene Proteins c-met; Survival Rate; Tumor Cells, Cultured; Tyrosine | 2003 |
Activated Src increases adhesion, survival and alpha2-integrin expression in human breast cancer cells.
Topics: Apoptosis; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Survival; Cytoskeletal Proteins; Enzyme Activation; Female; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Integrin alpha2; Paxillin; Phosphoproteins; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src) | 2004 |
Coupling of RAFTK/Pyk2 kinase with c-Abl and their role in the migration of breast cancer cells.
Topics: Breast Neoplasms; Cell Adhesion Molecules; Cell Line; Cell Line, Tumor; Cell Movement; Crk-Associated Substrate Protein; Cytoskeletal Proteins; Electrophoresis, Polyacrylamide Gel; Focal Adhesion Kinase 2; GTPase-Activating Proteins; Guanine Nucleotide Exchange Factors; Humans; Mutation; Neuregulin-1; Nuclear Proteins; Paxillin; Phosphoproteins; Phosphorylation; Protein Binding; Protein-Tyrosine Kinases; Proteins; Proto-Oncogene Proteins c-abl; Repressor Proteins; Retinoblastoma-Like Protein p130; Tyrosine | 2004 |
Constitutive p21-activated kinase (PAK) activation in breast cancer cells as a result of mislocalization of PAK to focal adhesions.
Topics: Adaptor Proteins, Signal Transducing; Breast Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Cytoskeletal Proteins; Enzyme Activation; Focal Adhesions; Guanine Nucleotide Exchange Factors; Humans; Mutation; Oncogene Proteins; p21-Activated Kinases; Paxillin; Phosphoproteins; Protein Binding; Protein Serine-Threonine Kinases; Protein Transport; rho GTP-Binding Proteins; Rho Guanine Nucleotide Exchange Factors | 2004 |
Expression of AMAP1, an ArfGAP, provides novel targets to inhibit breast cancer invasive activities.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Breast Neoplasms; Cell Line, Tumor; Cortactin; Cytoskeletal Proteins; Female; Gene Expression; Gene Silencing; GTPase-Activating Proteins; Humans; In Vitro Techniques; Mice; Mice, Inbred BALB C; Microfilament Proteins; Molecular Sequence Data; Neoplasm Invasiveness; Paxillin; Phosphoproteins; Proline; Protein Binding; RNA, Small Interfering | 2005 |
Elevated Src activity promotes cellular invasion and motility in tamoxifen resistant breast cancer cells.
Topics: Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Synergism; ErbB Receptors; Female; Focal Adhesion Kinase 1; Gefitinib; Humans; Microscopy, Fluorescence; Neoplasm Invasiveness; Paxillin; Protein Kinase Inhibitors; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; src-Family Kinases; Tamoxifen | 2006 |
Focal adhesion proteins as markers of malignant transformation and prognostic indicators in breast carcinoma.
Topics: Biomarkers, Tumor; Breast; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Intraductal, Noninfiltrating; Cell Transformation, Neoplastic; Female; Fibroadenoma; Focal Adhesion Protein-Tyrosine Kinases; Humans; Immunohistochemistry; Lymph Nodes; Paxillin; Prognosis; Protein Array Analysis; Proto-Oncogene Proteins pp60(c-src); Signal Transduction | 2006 |
CAIR-1/BAG-3 modulates cell adhesion and migration by downregulating activity of focal adhesion proteins.
Topics: Adaptor Proteins, Signal Transducing; Apoptosis Regulatory Proteins; Breast Neoplasms; Cell Adhesion; Cell Movement; Down-Regulation; Female; Focal Adhesion Kinase 1; Focal Adhesions; Gene Silencing; Humans; Paxillin; Proline; Protein Structure, Tertiary; Tumor Cells, Cultured | 2006 |
Overexpression of glycosylphosphatidylinositol (GPI) transamidase subunits phosphatidylinositol glycan class T and/or GPI anchor attachment 1 induces tumorigenesis and contributes to invasion in human breast cancer.
Topics: Acyltransferases; Breast Neoplasms; Cell Line, Tumor; Cell Transformation, Neoplastic; Cloning, Molecular; Gene Amplification; Gene Dosage; Glycosylphosphatidylinositols; Humans; Membrane Glycoproteins; Neoplasm Invasiveness; Oncogenes; Paxillin; Phosphorylation; Protein Subunits | 2006 |
Nek3 kinase regulates prolactin-mediated cytoskeletal reorganization and motility of breast cancer cells.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Movement; CHO Cells; Cricetinae; Cricetulus; Cytoskeleton; Female; Humans; Neoplasm Invasiveness; NIMA-Related Kinases; Paxillin; Phosphorylation; Prolactin; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-vav; rac1 GTP-Binding Protein; RNA, Small Interfering; Serine; Transfection | 2007 |
CTGF enhances the motility of breast cancer cells via an integrin-alphavbeta3-ERK1/2-dependent S100A4-upregulated pathway.
Topics: Actins; Animals; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Shape; Connective Tissue Growth Factor; Enzyme Activation; Female; Focal Adhesions; Gene Expression Regulation, Neoplastic; Humans; Immediate-Early Proteins; Integrin alphaVbeta3; Intercellular Signaling Peptides and Proteins; Mice; Mice, Nude; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neoplasm Metastasis; Oligonucleotides, Antisense; Paxillin; S100 Calcium-Binding Protein A4; S100 Proteins; Signal Transduction | 2007 |
The impact of delay in cryo-fixation on biomarkers of Src tyrosine kinase activity in human breast and bladder cancers.
Topics: Aged; Aged, 80 and over; Biomarkers; Biopsy; Breast Neoplasms; Female; Focal Adhesion Protein-Tyrosine Kinases; Freezing; Humans; Immunoassay; Male; Middle Aged; Paxillin; Phosphorylation; Phosphotyrosine; src-Family Kinases; Time Factors; Tissue Fixation; Urinary Bladder Neoplasms | 2008 |
RbAp48 regulates cytoskeletal organization and morphology by increasing K-Ras activity and signaling through mitogen-activated protein kinase.
Topics: 3T3 Cells; Actins; Animals; Breast Neoplasms; Carrier Proteins; Cell Line, Tumor; Cytoskeleton; Female; Focal Adhesions; Genes, ras; Humans; MAP Kinase Signaling System; Mice; Nuclear Proteins; Paxillin; Retinoblastoma-Binding Protein 4; RNA, Small Interfering | 2007 |
CNTO 95, a fully human anti alphav integrin antibody, inhibits cell signaling, migration, invasion, and spontaneous metastasis of human breast cancer cells.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Female; Focal Adhesion Kinase 1; Humans; Integrin alphaV; Lung Neoplasms; Mice; Mice, SCID; Neoplasm Invasiveness; Paxillin; Phosphorylation; Signal Transduction; Transplantation, Heterologous; Vitronectin | 2008 |
Alterations in Cx43 and OB-cadherin affect breast cancer cell metastatic potential.
Topics: Blotting, Western; Bone Neoplasms; Breast Neoplasms; Cadherins; Cell Adhesion; Cell Communication; Cell Movement; Connexin 26; Connexin 43; Connexins; Focal Adhesion Protein-Tyrosine Kinases; Gap Junctions; Humans; Neoplasm Invasiveness; Paxillin; Proto-Oncogene Proteins c-crk; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tumor Cells, Cultured | 2008 |
Src inhibitors in early breast cancer: a methodology, feasibility and variability study.
Topics: Animals; Benzodioxoles; Breast Neoplasms; CSK Tyrosine-Protein Kinase; Feasibility Studies; Female; Focal Adhesion Kinase 1; Humans; Immunoenzyme Techniques; Lung Neoplasms; Paxillin; Phosphorylation; Protein-Tyrosine Kinases; Quinazolines; Rats; Rats, Nude; src-Family Kinases; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2009 |
Prolactin stimulates the JAK2 and focal adhesion kinase pathways in human breast carcinoma T47-D cells.
Topics: Breast Neoplasms; Cell Adhesion Molecules; Cytoskeletal Proteins; Female; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Janus Kinase 2; Kinetics; Paxillin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Prolactin; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Recombinant Proteins; Tumor Cells, Cultured | 1997 |
Decreased tyrosine phosphorylation of focal adhesion kinase after estradiol treatment of MCF-7 human breast carcinoma cells.
Topics: Breast Neoplasms; Cell Adhesion; Cell Adhesion Molecules; Cytoskeletal Proteins; Dimethyl Sulfoxide; Estradiol; Female; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Paxillin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Receptors, Estrogen; Tamoxifen; Tumor Cells, Cultured; Tyrosine | 1998 |
Retinoic acid increases tyrosine phosphorylation of focal adhesion kinase and paxillin in MCF-7 human breast cancer cells.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Adhesion Molecules; Cytoskeletal Proteins; Female; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Paxillin; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Receptors, Retinoic Acid; Signal Transduction; Tretinoin; Tumor Cells, Cultured; Tyrosine | 1999 |
Involvement of focal adhesion kinase in inhibition of motility of human breast cancer cells by sphingosine 1-phosphate.
Topics: Breast Neoplasms; Cell Adhesion; Cell Adhesion Molecules; Cell Division; Cell Movement; Chemotaxis; Collagen; Cytoskeletal Proteins; Drug Combinations; Enzyme Activation; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Gelatinases; Humans; Laminin; Lysophospholipids; Matrix Metalloproteinase 2; Metalloendopeptidases; Paxillin; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Proteoglycans; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-crk; Sphingosine; Tumor Cells, Cultured; Tyrosine | 1999 |
Transcriptional up-regulation of paxillin expression by heregulin in human breast cancer cells.
Topics: Breast Neoplasms; Carrier Proteins; Cytoskeletal Proteins; Gene Expression Regulation, Neoplastic; Humans; Neuregulin-1; Paxillin; Phosphoproteins; Receptor, ErbB-2; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured; Up-Regulation | 1999 |
The activated insulin-like growth factor I receptor induces depolarization in breast epithelial cells characterized by actin filament disassembly and tyrosine dephosphorylation of FAK, Cas, and paxillin.
Topics: Actins; Breast Neoplasms; Cell Adhesion; Cell Adhesion Molecules; Cell Movement; Cell Size; Crk-Associated Substrate Protein; Cytoplasm; Cytoskeletal Proteins; Cytoskeleton; Epithelial Cells; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Insulin-Like Growth Factor I; Membrane Potentials; Paxillin; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proteins; Receptor, IGF Type 1; Retinoblastoma-Like Protein p130; Signal Transduction; Tumor Cells, Cultured | 1999 |
An invasion-related complex of cortactin, paxillin and PKCmu associates with invadopodia at sites of extracellular matrix degradation.
Topics: Actins; Breast Neoplasms; Cell Adhesion Molecules; Cell Membrane; Cortactin; Cytoskeletal Proteins; Extracellular Matrix; Female; Gelatin; Humans; Integrin beta1; Microfilament Proteins; Microscopy, Electron; Models, Biological; Neoplasm Invasiveness; Paxillin; Phosphoproteins; Protein Kinase C; Tumor Cells, Cultured | 1999 |
Serine phosphorylation of paxillin by heregulin-beta1: role of p38 mitogen activated protein kinase.
Topics: Breast Neoplasms; Cell Adhesion; Cell Adhesion Molecules; Cytoskeletal Proteins; Female; Humans; Mitogen-Activated Protein Kinases; Neuregulin-1; p38 Mitogen-Activated Protein Kinases; Paxillin; Phosphoproteins; Phosphorylation; Serine; Signal Transduction; Tumor Cells, Cultured | 1999 |
Progesterone induces focal adhesion in breast cancer cells MDA-MB-231 transfected with progesterone receptor complementary DNA.
Topics: Breast Neoplasms; Carcinoma; Cell Adhesion; Cell Adhesion Molecules; Cell Size; Cytoskeletal Proteins; DNA, Complementary; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Integrin beta1; Neoplasm Proteins; Paxillin; Phosphoproteins; Phosphorylation; Progesterone; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Receptors, Estrogen; Receptors, Progesterone; Recombinant Fusion Proteins; Signal Transduction; Transfection; Tumor Cells, Cultured | 2000 |
Role of paxillin in metabolic oxidative stress-induced cytoskeletal reorganization: involvement of SAPK signal transduction pathway and PTP-PEST gene expression.
Topics: Acetylcysteine; Antioxidants; Breast Neoplasms; Cell Adhesion Molecules; Cytoskeletal Proteins; Cytoskeleton; Doxorubicin; Drug Resistance, Multiple; Female; Gene Expression Regulation, Neoplastic; Glucose; Humans; Mitogen-Activated Protein Kinases; Oxidative Stress; Paxillin; Phosphoproteins; Protein Tyrosine Phosphatase, Non-Receptor Type 12; Protein Tyrosine Phosphatases; Signal Transduction; Tumor Cells, Cultured | 2000 |
Csk homologous kinase associates with RAFTK/Pyk2 in breast cancer cells and negatively regulates its activation and breast cancer cell migration.
Topics: Blotting, Western; Breast Neoplasms; Cell Movement; CSK Tyrosine-Protein Kinase; Cytoskeletal Proteins; Down-Regulation; Female; Focal Adhesion Kinase 2; Focal Adhesions; Humans; Megakaryocytes; Neoplasm Invasiveness; Neuregulin-1; Paxillin; Phosphoproteins; Phosphorylation; Plasmids; Precipitin Tests; Protein Binding; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Receptor, ErbB-2; Recombinant Proteins; Signal Transduction; src-Family Kinases; Transfection; Tumor Cells, Cultured; Tyrosine | 2002 |