Page last updated: 2024-11-02

patulin and Pregnancy

patulin has been researched along with Pregnancy in 8 studies

Patulin: 4-Hydroxy-4H-furo(3,2-c)pyran-2(6H)-one. A mycotoxin produced by several species of Aspergillus and Penicillium. It is found in unfermented apple and grape juice and field crops. It has antibiotic properties and has been shown to be carcinogenic and mutagenic and causes chromosome damage in biological systems.
patulin : A furopyran and lactone that is (2H-pyran-3(6H)-ylidene)acetic acid which is substituted by hydroxy groups at positions 2 and 4 and in which the hydroxy group at position 4 has condensed with the carboxy group to give the corresponding bicyclic lactone. A mycotoxin produced by several species of Aspergillus and Penicillium, it has antibiotic properties but has been shown to be carcinogenic and mutagenic.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"0 mg/kg of patulin on days 6 through 17 of pregnancy and mutagenic effects of acute i."3.66Teratogenic and dominant lethal studies of patulin in mice. ( Chan, PK; Hayes, AW; Reddy, CS, 1978)
"Patulin treatment also resulted in an increase in the frequency of defective embryos."1.29Effects of patulin on postimplantation rat embryos. ( Duffus, EA; Small, MH; Smith, EE, 1993)
" No other teratological abnormalities related to patulin dosing at the 1."1.26Intermediate-duration toxicity study of patulin in rats. ( Blaschka, AM; Brouwer, E; Dailey, RE; Green, S; Monlux, WS; Reynaldo, EF; Ruggles, DI, 1977)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19907 (87.50)18.7374
1990's1 (12.50)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fuks-Holmberg, D1
Smith, EE1
Duffus, EA1
Small, MH1
Osswald, H1
Frank, HK1
Komitowski, D1
Winter, H1
Reddy, CS1
Chan, PK1
Hayes, AW1
Jarvis, B1
Dailey, RE1
Brouwer, E1
Blaschka, AM1
Reynaldo, EF1
Green, S1
Monlux, WS1
Ruggles, DI1
Harwig, J1
Munro, IC1

Reviews

2 reviews available for patulin and Pregnancy

ArticleYear
Mycotoxins in food.
    Society for Applied Bacteriology symposium series, 1976, Volume: 4

    Topics: Aflatoxins; Citrinin; Dairy Products; Edible Grain; Female; Fermentation; Food Contamination; Food M

1976
Mycotoxins of possible importance in diseases of Canadian farm animals.
    The Canadian veterinary journal = La revue veterinaire canadienne, 1975, Volume: 16, Issue:5

    Topics: Aflatoxins; Animals; Animals, Domestic; Canada; Cattle; Cattle Diseases; Chickens; Citrinin; Female;

1975

Other Studies

6 other studies available for patulin and Pregnancy

ArticleYear
The influence of patulin on rat fetus and rat and human placenta enzymes.
    Toxicon : official journal of the International Society on Toxinology, 1980, Volume: 18, Issue:4

    Topics: Animals; Body Weight; Female; Fetus; Humans; In Vitro Techniques; Patulin; Placenta; Pregnancy; Pyra

1980
Effects of patulin on postimplantation rat embryos.
    Archives of environmental contamination and toxicology, 1993, Volume: 25, Issue:2

    Topics: Animals; Culture Techniques; DNA; Embryo, Mammalian; Embryonic Development; Female; Patulin; Pregnan

1993
Long-term testing of patulin administered orally to Sprague-Dawley rats and Swiss mice.
    Food and cosmetics toxicology, 1978, Volume: 16, Issue:3

    Topics: Animals; Animals, Suckling; Female; Male; Maternal-Fetal Exchange; Mice; Neoplasms; Patulin; Pregnan

1978
Teratogenic and dominant lethal studies of patulin in mice.
    Toxicology, 1978, Volume: 11, Issue:3

    Topics: Animals; Birth Weight; Female; Genes, Dominant; Genes, Lethal; Male; Mice; Mice, Inbred ICR; Patulin

1978
Intermediate-duration toxicity study of patulin in rats.
    Journal of toxicology and environmental health, 1977, Volume: 2, Issue:3

    Topics: Animals; Body Weight; Dose-Response Relationship, Drug; Female; Fetus; Genes, Dominant; Genes, Letha

1977
Patulin.
    IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans, 1986, Volume: 40

    Topics: Animals; Chemical Phenomena; Chemistry; Chickens; Female; Lethal Dose 50; Male; Mice; Mutagenicity T

1986