patulin has been researched along with Colorectal Cancer in 3 studies
Patulin: 4-Hydroxy-4H-furo(3,2-c)pyran-2(6H)-one. A mycotoxin produced by several species of Aspergillus and Penicillium. It is found in unfermented apple and grape juice and field crops. It has antibiotic properties and has been shown to be carcinogenic and mutagenic and causes chromosome damage in biological systems.
patulin : A furopyran and lactone that is (2H-pyran-3(6H)-ylidene)acetic acid which is substituted by hydroxy groups at positions 2 and 4 and in which the hydroxy group at position 4 has condensed with the carboxy group to give the corresponding bicyclic lactone. A mycotoxin produced by several species of Aspergillus and Penicillium, it has antibiotic properties but has been shown to be carcinogenic and mutagenic.
| Excerpt | Relevance | Reference |
|---|---|---|
| "IC50 values of oxaliplatin, emetine and patulin were determined against human colorectal cancer cell lines (HT-29 and Caco-2) using MTT reduction assay." | 7.96 | Dose and Sequence Dependent Synergism from the Combination of Oxaliplatin with Emetine and Patulin Against Colorectal Cancer. ( Alam, MN; Beale, P; Huq, F; Yu, JQ, 2020) |
| "Patulin is a fungal mycotoxin of Aspergilus and Penicillium that is commonly found in rotting fruits and exerts its potential toxic effect mainly by reactive oxygen species (ROS) generation." | 5.38 | Patulin induces colorectal cancer cells apoptosis through EGR-1 dependent ATF3 up-regulation. ( Ahn, JS; Chung, JK; Erikson, RL; Jang, JH; Jeong, SJ; Kim, BY; Kwon, O; Kwon, YT; Lee, KS; Moon, DO; Soung, NK; Thimmegowda, NR, 2012) |
| "IC50 values of oxaliplatin, emetine and patulin were determined against human colorectal cancer cell lines (HT-29 and Caco-2) using MTT reduction assay." | 3.96 | Dose and Sequence Dependent Synergism from the Combination of Oxaliplatin with Emetine and Patulin Against Colorectal Cancer. ( Alam, MN; Beale, P; Huq, F; Yu, JQ, 2020) |
| "Patulin is a fungal mycotoxin of Aspergilus and Penicillium that is commonly found in rotting fruits and exerts its potential toxic effect mainly by reactive oxygen species (ROS) generation." | 1.38 | Patulin induces colorectal cancer cells apoptosis through EGR-1 dependent ATF3 up-regulation. ( Ahn, JS; Chung, JK; Erikson, RL; Jang, JH; Jeong, SJ; Kim, BY; Kwon, O; Kwon, YT; Lee, KS; Moon, DO; Soung, NK; Thimmegowda, NR, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Alam, MN | 1 |
| Yu, JQ | 1 |
| Beale, P | 1 |
| Huq, F | 1 |
| Ouhibi, S | 1 |
| Vidal, A | 1 |
| Martins, C | 1 |
| Gali, R | 1 |
| Hedhili, A | 1 |
| De Saeger, S | 1 |
| De Boevre, M | 1 |
| Kwon, O | 1 |
| Soung, NK | 1 |
| Thimmegowda, NR | 1 |
| Jeong, SJ | 1 |
| Jang, JH | 1 |
| Moon, DO | 1 |
| Chung, JK | 1 |
| Lee, KS | 1 |
| Kwon, YT | 1 |
| Erikson, RL | 1 |
| Ahn, JS | 1 |
| Kim, BY | 1 |
3 other studies available for patulin and Colorectal Cancer
| Article | Year |
|---|---|
Dose and Sequence Dependent Synergism from the Combination of Oxaliplatin with Emetine and Patulin Against Colorectal Cancer.
Topics: Antineoplastic Agents; Caco-2 Cells; Colorectal Neoplasms; Drug Synergism; Drug Therapy, Combination | 2020 |
LC-MS/MS methodology for simultaneous determination of patulin and citrinin in urine and plasma applied to a pilot study in colorectal cancer patients.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Case-Control Studies; Chromatography, Liquid; Citrinin; | 2020 |
Patulin induces colorectal cancer cells apoptosis through EGR-1 dependent ATF3 up-regulation.
Topics: Acetylcysteine; Activating Transcription Factor 3; Antioxidants; Apoptosis; Caco-2 Cells; Caspase 3; | 2012 |