patulin has been researched along with Abnormalities, Autosome in 10 studies
Patulin: 4-Hydroxy-4H-furo(3,2-c)pyran-2(6H)-one. A mycotoxin produced by several species of Aspergillus and Penicillium. It is found in unfermented apple and grape juice and field crops. It has antibiotic properties and has been shown to be carcinogenic and mutagenic and causes chromosome damage in biological systems.
patulin : A furopyran and lactone that is (2H-pyran-3(6H)-ylidene)acetic acid which is substituted by hydroxy groups at positions 2 and 4 and in which the hydroxy group at position 4 has condensed with the carboxy group to give the corresponding bicyclic lactone. A mycotoxin produced by several species of Aspergillus and Penicillium, it has antibiotic properties but has been shown to be carcinogenic and mutagenic.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aneuploidogenic and clastogenic potentials of the mycotoxins citrinin (CIT) and patulin (PAT) were studied by determining inhibition of microtubule assembly under cell-free conditions and by measuring induction of mitotic arrest and micronuclei in cultured Chinese hamster V79 cells." | 7.70 | Aneuploidogenic and clastogenic potential of the mycotoxins citrinin and patulin. ( Gross, K; Metzler, M; Pfeiffer, E, 1998) |
| "The aneuploidogenic and clastogenic potentials of the mycotoxins citrinin (CIT) and patulin (PAT) were studied by determining inhibition of microtubule assembly under cell-free conditions and by measuring induction of mitotic arrest and micronuclei in cultured Chinese hamster V79 cells." | 3.70 | Aneuploidogenic and clastogenic potential of the mycotoxins citrinin and patulin. ( Gross, K; Metzler, M; Pfeiffer, E, 1998) |
| "Patulin (PAT) is a mycotoxin produced by certain species of Penicillium, Aspergillus, and Byssochlamys." | 1.40 | Hepatotoxicity and genotoxicity of patulin in mice, and its modulation by green tea polyphenols administration. ( Dong, W; Song, E; Song, Y; Su, C; Wang, W; Xia, X; Xian, Y, 2014) |
| "Patulin (PAT) is a mycotoxin produced in fruits, mainly in apples, by certain species of Penicillium, Aspergillus, and Byssochlamys." | 1.39 | Antioxidative and antigenotoxic effect of vitamin E against patulin cytotoxicity and genotoxicity in HepG2 cells. ( Abassi, H; Ayed, Y; Ayed-Boussema, I; Bacha, H; Bouaziz, C; Hlima, WB, 2013) |
| "Patulin is a frequently found food contaminant mainly produced by the fungi Aspergillus and Penicillium." | 1.38 | Patulin: Mechanism of genotoxicity. ( Glaser, N; Stopper, H, 2012) |
| "Patulin is a mycotoxin produced by several species of Penicillium, Aspergillus and BYSSOCHLAMYS: Patulin is a common contaminant of ripe apples used for the production of apple juice concentrates and is also present in other fruits, vegetables and food products." | 1.31 | Induction of micronuclei and chromosomal aberrations by the mycotoxin patulin in mammalian cells: role of ascorbic acid as a modulator of patulin clastogenicity. ( Alves, I; Laires, A; Oliveira, NG; Rodrigues, AS; Rueff, J, 2000) |
| "Patulin is a potent inducer of chromatid-type aberrations in Chinese hamster V79-E cells, but loses its activity when 9000 g supernatant of rat-liver homogenate is added." | 1.26 | Patulin, a further clastogenic mycotoxin, is negative in the SCE assay in Chinese hamster V79-E cells in vitro. ( Kneist, S; Mendel, J; Thust, R, 1982) |
| "However, the rate of chromosomal aberrations induced by the direct mutagen PA was clearly suppressed in ethanol drinking animals." | 1.26 | The influence of ethanol treatment of cytogenetic effects in bone marrow cells of Chinese hamsters by cyclophosphamide, aflatoxin B1 and patulin. ( Korte, A; Obe, G; Slacik-Erben, R, 1979) |
| "Incidence of chromosome aberrations by the treatment with these mycotoxins correlated fairly well with their mutagenic activity." | 1.26 | Mutagenicity and inducibility of DNA single-strand breaks and chromosome aberrations by various mycotoxins. ( Saito, M; Tsutsui, T; Umeda, M, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (50.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Song, E | 1 |
| Xia, X | 1 |
| Su, C | 1 |
| Dong, W | 1 |
| Xian, Y | 1 |
| Wang, W | 1 |
| Song, Y | 1 |
| Ayed-Boussema, I | 1 |
| Abassi, H | 1 |
| Bouaziz, C | 1 |
| Hlima, WB | 1 |
| Ayed, Y | 1 |
| Bacha, H | 1 |
| Glaser, N | 1 |
| Stopper, H | 1 |
| Thust, R | 1 |
| Kneist, S | 1 |
| Mendel, J | 1 |
| Korte, A | 2 |
| Pfeiffer, E | 1 |
| Gross, K | 1 |
| Metzler, M | 1 |
| Alves, I | 1 |
| Oliveira, NG | 1 |
| Laires, A | 1 |
| Rodrigues, AS | 1 |
| Rueff, J | 1 |
| Slacik-Erben, R | 1 |
| Obe, G | 1 |
| Umeda, M | 1 |
| Tsutsui, T | 1 |
| Saito, M | 1 |
1 review available for patulin and Abnormalities, Autosome
| Article | Year |
|---|---|
Patulin.
Topics: Animals; Carcinogens; Chromosome Aberrations; Drug Evaluation, Preclinical; Lethal Dose 50; Male; Mi | 1976 |
9 other studies available for patulin and Abnormalities, Autosome
| Article | Year |
|---|---|
Hepatotoxicity and genotoxicity of patulin in mice, and its modulation by green tea polyphenols administration.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bone Marrow; Chromosome Aberrations; Glu | 2014 |
Antioxidative and antigenotoxic effect of vitamin E against patulin cytotoxicity and genotoxicity in HepG2 cells.
Topics: Antioxidants; Carcinogens; Cell Survival; Chromosome Aberrations; DNA Damage; Hep G2 Cells; Humans; | 2013 |
Patulin: Mechanism of genotoxicity.
Topics: Chromosome Aberrations; Comet Assay; DNA Damage; Glutathione; Micronucleus Tests; Mutagens; Patulin | 2012 |
Patulin, a further clastogenic mycotoxin, is negative in the SCE assay in Chinese hamster V79-E cells in vitro.
Topics: Animals; Biotransformation; Cell Line; Chromosome Aberrations; Cricetinae; Cricetulus; Crossing Over | 1982 |
Chromosomal analysis in bone-marrow cells of Chinese hamsters after treatment with mycotoxins.
Topics: Administration, Oral; Aflatoxins; Animals; Bone Marrow; Chromosome Aberrations; Chromosomes; Criceti | 1980 |
Aneuploidogenic and clastogenic potential of the mycotoxins citrinin and patulin.
Topics: Aneuploidy; Animals; Anti-Bacterial Agents; Cattle; Cells, Cultured; Chromosome Aberrations; Chromos | 1998 |
Induction of micronuclei and chromosomal aberrations by the mycotoxin patulin in mammalian cells: role of ascorbic acid as a modulator of patulin clastogenicity.
Topics: Animals; Antimutagenic Agents; Ascorbic Acid; Cell Division; Cell Line; Cell Survival; Cells, Cultur | 2000 |
The influence of ethanol treatment of cytogenetic effects in bone marrow cells of Chinese hamsters by cyclophosphamide, aflatoxin B1 and patulin.
Topics: Aflatoxins; Animals; Bone Marrow; Bone Marrow Cells; Chromosome Aberrations; Chromosomes; Cricetinae | 1979 |
Mutagenicity and inducibility of DNA single-strand breaks and chromosome aberrations by various mycotoxins.
Topics: Aflatoxins; Animals; Azaguanine; Cell Line; Chromosome Aberrations; DNA, Single-Stranded; Drug Evalu | 1977 |