parthenolide has been researched along with Neoplasms in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (28.57) | 29.6817 |
| 2010's | 9 (42.86) | 24.3611 |
| 2020's | 6 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Chen, Y; Long, J; Wang, PP; Yang, ZJ; Zhang, Q; Zhang, SF; Zhang, XM | 1 |
| Borrelli, MJ; Crooks, PA; Janganati, V; Jordan, CT; Penthala, NR; Ponder, J | 1 |
| Kinghorn, AD; Ren, Y | 1 |
| Dong, Y; Li, J; Qian, X | 1 |
| Deng, Y; Gao, W; Gu, H; Jiang, X; Li, A; Wen, J; Zhang, X; Zhu, Y | 1 |
| Liu, X; Wang, X | 1 |
| Bouchal, P; Bouchalova, P; Janacova, L; Jilkova, K; Lapcik, P; Müller, P; Potesil, D; Sulc, P | 1 |
| Gach, K; Janecka, A; Wyrębska, A | 1 |
| Duan, D; Fang, J; Liu, Y; Yao, J; Zhang, J | 1 |
| Iranshahi, M; Nasseri, MA; Taleghani, A | 1 |
| Gajkowska, B; Orzechowski, A; Pajak, B | 1 |
| Aimiuwu, J; Bhasin, D; Chan, KK; Chen, P; Fuchs, JR; Huang, TH; Li, C; Li, PK; Liu, S; Liu, Z; Marcucci, G; Neviani, P; Pang, J; Pavlovicz, RE; Perrotti, D; Plass, C; Rush, L; Wang, H; Wu, J; Wu, LC; Xie, Z | 1 |
| Czyz, M; Koprowska, K | 1 |
| Koh, YS; Mathema, VB; Sillanpää, M; Thakuri, BC | 1 |
| Biavatti, MW; D'Herde, K; Grootjans, S; Kreuger, MR; Vandenabeele, P | 1 |
| Darwiche, N; Gali-Muhtasib, H; Ghantous, A; Rau, T; Saikali, M; Schneider-Stock, R | 1 |
| Choi, YK; Kim, DG; Liu, MJ; Won, YS; You, KR | 1 |
| Armstrong, V; Curry, EA; Fife, K; Murry, DJ; Nakshatri, H; O'Connell, M; Sweeney, CJ; Yoder, C | 1 |
| Chen, F; Haley-Zitlin, V; He, G; Huang, G; Kim, HJ; Rushing, JW; Wang, X; Wu, C | 1 |
| Butini, S; Campiani, G; Carullo, G; Federico, S; Gemma, S; Papa, A; Pozzetti, L; Relitti, N | 1 |
8 review(s) available for parthenolide and Neoplasms
| Article | Year |
|---|---|
Sesquiterpene Lactones and Cancer: New Insight into Antitumor and Anti-inflammatory Effects of Parthenolide-Derived Dimethylaminomicheliolide and Micheliolide.
Topics: Anti-Inflammatory Agents; Humans; Lactones; Neoplasms; Sesquiterpenes; Sesquiterpenes, Guaiane | 2022 |
Recent advances on the structural modification of parthenolide and its derivatives as anticancer agents.
Topics: Antineoplastic Agents; Neoplasms; Plant Extracts; Sesquiterpenes; Tanacetum parthenium | 2022 |
Combined effect of parthenolide and various anti-cancer drugs or anticancer candidate substances on malignant cells in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Drug Interactions; Humans; Neoplasms; Sesquiterpenes | 2014 |
Molecular basis of parthenolide-dependent proapoptotic activity in cancer cells.
Topics: Animals; Apoptosis; Humans; Mitochondria; Neoplasms; NF-kappa B; Sesquiterpenes; STAT Transcription Factors | 2008 |
[Molecular mechanisms of parthenolide's action: Old drug with a new face].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Neoplasms; Neoplastic Stem Cells; Sesquiterpenes | 2010 |
Parthenolide, a sesquiterpene lactone, expresses multiple anti-cancer and anti-inflammatory activities.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; Cytochromes c; Humans; I-kappa B Kinase; Inflammation; Neoplasms; NF-kappa B; Plant Extracts; Reactive Oxygen Species; Sesquiterpenes; Signal Transduction; STAT Transcription Factors; Tanacetum parthenium; Transcription, Genetic | 2012 |
Sesquiterpene lactones as drugs with multiple targets in cancer treatment: focus on parthenolide.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; Cell Line, Tumor; Humans; Molecular Structure; Neoplasms; NF-kappa B; Plants, Medicinal; Quantitative Structure-Activity Relationship; Sesquiterpenes; Xenograft Model Antitumor Assays | 2012 |
Modulation of the Innate Immune Response by Targeting Toll-like Receptors: A Perspective on Their Agonists and Antagonists.
Topics: Animals; Antineoplastic Agents; Communicable Diseases; Drug Delivery Systems; Humans; Hypoglycemic Agents; Immunity, Innate; Metabolic Diseases; Neoplasms; Protein Structure, Secondary; Toll-Like Receptors | 2020 |
1 trial(s) available for parthenolide and Neoplasms
| Article | Year |
|---|---|
Phase I dose escalation trial of feverfew with standardized doses of parthenolide in patients with cancer.
Topics: Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Male; Mass Spectrometry; Middle Aged; Neoplasms; Phytotherapy; Plant Preparations; Sesquiterpenes; Tanacetum parthenium | 2004 |
12 other study(ies) available for parthenolide and Neoplasms
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Total syntheses of parthenolide and its analogues with macrocyclic stereocontrol.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Chemistry Techniques, Synthetic; Drug Screening Assays, Antitumor; Humans; MCF-7 Cells; Neoplasms; Sesquiterpenes; Structure-Activity Relationship | 2014 |
Dimers of Melampomagnolide B Exhibit Potent Anticancer Activity against Hematological and Solid Tumor Cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; Dimerization; Drug Screening Assays, Antitumor; Gliosarcoma; Hematologic Neoplasms; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Neoplasms; Primary Cell Culture; Rats; Sesquiterpenes; Structure-Activity Relationship; Tumor Stem Cell Assay | 2015 |
Development of Potential Antitumor Agents from the Scaffolds of Plant-Derived Terpenoid Lactones.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Biological Products; Diterpenes; Humans; Neoplasms; Sesquiterpenes; Structure-Activity Relationship; Triterpenes | 2020 |
A dual-responsive "Yin-Yang" photothermal delivery system to accelerate Parthenolide anti-tumor efficacy.
Topics: Antineoplastic Agents; Gold; Humans; Hyperthermia, Induced; Liposomes; Neoplasms; Phototherapy; Sesquiterpenes; Tumor Microenvironment | 2022 |
Desmocollin-1 is associated with pro-metastatic phenotype of luminal A breast cancer cells and is modulated by parthenolide.
Topics: Chromatography, Liquid; Desmocollins; Humans; MCF-7 Cells; Neoplasms; Proteome; Sesquiterpenes; Tandem Mass Spectrometry | 2023 |
Targeting Thioredoxin Reductase by Parthenolide Contributes to Inducing Apoptosis of HeLa Cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; HeLa Cells; Humans; NADPH Oxidases; Neoplasm Proteins; Neoplasms; Sesquiterpenes; Superoxides; Tanacetum parthenium; Thioredoxin Reductase 1; Thioredoxin Reductase 2 | 2016 |
Synthesis of dual-action parthenolide prodrugs as potent anticancer agents.
Topics: Antineoplastic Agents; Apoptosis; Catalysis; Cell Line, Tumor; Chemistry Techniques, Synthetic; Cytarabine; Humans; Lactones; Melphalan; Neoplasms; Prodrugs; Sesquiterpenes | 2017 |
Modulation of DNA methylation by a sesquiterpene lactone parthenolide.
Topics: Alkylation; Animals; Antineoplastic Agents; Apoptosis; Catalytic Domain; Cell Cycle; Cell Line, Tumor; Cell Survival; Chromatin Immunoprecipitation; Cysteine; Cytokines; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Electrophoretic Mobility Shift Assay; Female; Humans; Immunoblotting; Lactones; Mice; Mice, Nude; Models, Molecular; Neoplasms; Promoter Regions, Genetic; Sesquiterpenes; Sp1 Transcription Factor; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays | 2009 |
Inhibition of tumor promotion by parthenolide: epigenetic modulation of p21.
Topics: Animals; Animals, Newborn; Antineoplastic Agents, Phytogenic; Cell Transformation, Neoplastic; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Dose-Response Relationship, Drug; Down-Regulation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Inbred BALB C; Neoplasms; Sesquiterpenes; Xenograft Model Antitumor Assays | 2012 |
GADD153-mediated anticancer effects of N-(4-hydroxyphenyl)retinamide on human hepatoma cells.
Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; CCAAT-Enhancer-Binding Proteins; Cell Cycle; DNA Fragmentation; Fenretinide; Flow Cytometry; Gene Expression Profiling; Gene Expression Regulation; Genes, Reporter; Humans; Neoplasms; NF-kappa B; Sesquiterpenes; Transcription Factor CHOP; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured | 2002 |
Antiproliferative activities of parthenolide and golden feverfew extract against three human cancer cell lines.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apigenin; Breast Neoplasms; Camphor; Cell Division; Cell Line, Tumor; Drug Synergism; Female; Humans; Luteolin; Neoplasms; Plant Extracts; Sesquiterpenes; Tanacetum parthenium; Uterine Cervical Neoplasms | 2006 |