parthenolide has been researched along with Lung Neoplasms in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (17.65) | 29.6817 |
| 2010's | 12 (70.59) | 24.3611 |
| 2020's | 2 (11.76) | 2.80 |
| Authors | Studies |
|---|---|
| Cai, N; Jin, X; Yang, Q; Zhang, Z | 1 |
| Chen, C; Gan, X; Sun, L; Tang, J; Wen, G; Xu, F; Yu, B; Yuan, W; Zeng, Q; Zhang, W; Zhu, L | 1 |
| Bi, H; Huang, W; Lin, M; Liu, Y; Ma, J; Tang, S; Yan, Y; Zhang, G; Zhang, J; Zhang, L | 1 |
| Cordes, N; Klebe, S; Morel, KL; Ormsby, RJ; Solly, EL; Sweeney, CJ; Sykes, PJ; Tran, LNK | 1 |
| Al Kury, LT; Talib, WH | 1 |
| Jin, X; Lv, H; Zhang, Z; Zhou, J | 1 |
| Cipolla, GA; Hwang, CY; Kuh, HJ; Lee, DJ; Moeng, S; Park, JK; Seo, HA | 1 |
| Lan, L; Luo, L; Qi, S; Shen, L; Xin, Y; Xu, Y; Yin, F; Yin, Z | 1 |
| Liu, X; Su, L; Zhao, X | 1 |
| Guo, C; Guo, Z; Jin, X; Qiu, L; Zhang, D | 1 |
| Fang, LJ; Lu, GH; Shao, XT; Wang, S; Xu, T; Zhou, JY | 1 |
| Hatashita, M; Hayashi, A; Hayashi, S; Sakurai, H; Shioura, H; Tanaka, Y | 1 |
| Gao, ZW; Guo, CB; Zhang, DL | 1 |
| Appaiah, H; Cheng, L; Crooks, P; Klaunig, J; Kusumanchi, P; Matthews, W; Nakshatri, H; Neelakantan, S; Peat, T; Shanmugam, R; Sweeney, CJ | 1 |
| Gill, KK; Kaddoumi, A; Nazzal, S | 1 |
| Zhong, D; Zhong, M; Zhu, R | 1 |
| Hatashita, M; Hayashi, A; Hayashi, S; Kitai, R; Matsumoto, H; Shioura, H | 1 |
17 other study(ies) available for parthenolide and Lung Neoplasms
| Article | Year |
|---|---|
A cocktail of betulinic acid, parthenolide, honokiol and ginsenoside Rh2 in liposome systems for lung cancer treatment.
Topics: A549 Cells; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Betulinic Acid; Biphenyl Compounds; Cell Proliferation; Cisplatin; Ginsenosides; Humans; Lignans; Liposomes; Lung Neoplasms; Mice; Neoplasm Invasiveness; Pentacyclic Triterpenes; Sesquiterpenes; Triterpenes; Xenograft Model Antitumor Assays | 2020 |
Parthenolide inhibits human lung cancer cell growth by modulating the IGF‑1R/PI3K/Akt signaling pathway.
Topics: Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; Forkhead Box Protein O3; Humans; Insulin-Like Growth Factor I; Lung Neoplasms; Male; Mice; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Receptor, IGF Type 1; Sesquiterpenes; Signal Transduction; Xenograft Model Antitumor Assays | 2020 |
Parthenolide suppresses non-small cell lung cancer GLC-82 cells growth via B-Raf/MAPK/Erk pathway.
Topics: A549 Cells; Apoptosis; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Neoplastic; Glycogen Synthase Kinase 3; Humans; Immunohistochemistry; Inhibitory Concentration 50; Lung Neoplasms; Male; MAP Kinase Signaling System; Middle Aged; Phosphorylation; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-myc; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Sesquiterpenes; STAT3 Transcription Factor | 2017 |
Chronic low dose ethanol induces an aggressive metastatic phenotype in TRAMP mice, which is counteracted by parthenolide.
Topics: Adenocarcinoma; Animals; Disease Progression; Drug Interactions; Ethanol; Female; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplasm Metastasis; Prostatic Neoplasms; Sesquiterpenes | 2018 |
Parthenolide inhibits tumor-promoting effects of nicotine in lung cancer by inducing P53 - dependent apoptosis and inhibiting VEGF expression.
Topics: A549 Cells; Angiogenesis Inhibitors; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cell Survival; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Neovascularization, Pathologic; Nicotine; Real-Time Polymerase Chain Reaction; Sesquiterpenes; Tumor Suppressor Protein p53; Vascular Endothelial Growth Factor A | 2018 |
The combined administration of parthenolide and ginsenoside CK in long circulation liposomes with targeted tLyp-1 ligand induce mitochondria-mediated lung cancer apoptosis.
Topics: A549 Cells; Animals; Apoptosis; Delayed-Action Preparations; Ginsenosides; Humans; Liposomes; Lung Neoplasms; Mice; Mice, Nude; Mitochondria; Reactive Oxygen Species; Sesquiterpenes; Xenograft Model Antitumor Assays | 2018 |
MicroRNA-107 Targets IKBKG and Sensitizes A549 Cells to Parthenolide.
Topics: 3' Untranslated Regions; A549 Cells; Binding Sites; Carcinoma, Non-Small-Cell Lung; Cell Movement; Cell Proliferation; Cell Survival; Computational Biology; Gene Expression Regulation, Neoplastic; Humans; I-kappa B Kinase; Lung Neoplasms; MicroRNAs; Sesquiterpenes | 2018 |
Parthenolide reverses doxorubicin resistance in human lung carcinoma A549 cells by attenuating NF-κB activation and HSP70 up-regulation.
Topics: Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cell Survival; Doxorubicin; Drug Resistance, Neoplasm; HSP70 Heat-Shock Proteins; Humans; In Situ Nick-End Labeling; Lung Neoplasms; Microscopy, Confocal; NF-kappa B; Sesquiterpenes; Signal Transduction; Up-Regulation | 2013 |
Parthenolide induces apoptosis via TNFRSF10B and PMAIP1 pathways in human lung cancer cells.
Topics: Activating Transcription Factor 4; Antineoplastic Agents; Apoptosis; CASP8 and FADD-Like Apoptosis Regulating Protein; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Gene Expression; Humans; Lung Neoplasms; Myeloid Cell Leukemia Sequence 1 Protein; Neoplastic Stem Cells; Proto-Oncogene Proteins c-bcl-2; Receptors, TNF-Related Apoptosis-Inducing Ligand; Sesquiterpenes; Transcription Factor CHOP; Up-Regulation | 2014 |
Nuclear factor-kappaB inhibition by parthenolide potentiates the efficacy of Taxol in non-small cell lung cancer in vitro and in vivo.
Topics: Analysis of Variance; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; bcl-X Protein; Carcinoma, Non-Small-Cell Lung; Caspases; Cell Line, Tumor; Cell Survival; Cytochromes c; Drug Synergism; Histocytochemistry; I-kappa B Kinase; Kaplan-Meier Estimate; Lung Neoplasms; Mice; Mitochondrial Membranes; NF-kappa B; Paclitaxel; Sesquiterpenes; Xenograft Model Antitumor Assays | 2009 |
Sesquiterpene lactone parthenolide markedly enhances sensitivity of human A549 cells to low-dose oxaliplatin via inhibition of NF-kappaB activation and induction of apoptosis.
Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Humans; Lactones; Lung Neoplasms; NF-kappa B; Organoplatinum Compounds; Oxaliplatin; Phytotherapy; Plant Extracts; Sesquiterpenes; Tanacetum | 2010 |
Inhibition of NF-kappaB by combination therapy with parthenolide and hyperthermia and kinetics of apoptosis induction and cell cycle arrest in human lung adenocarcinoma cells.
Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Combined Modality Therapy; Humans; Hyperthermia, Induced; Lung Neoplasms; NF-kappa B; Sesquiterpenes | 2010 |
Paclitaxel efficacy is increased by parthenolide via nuclear factor-kappaB pathways in in vitro and in vivo human non-small cell lung cancer models.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Nucleus; Cell Survival; Drug Synergism; Humans; I-kappa B Proteins; Lung Neoplasms; Mice; Mice, Nude; NF-kappa B; Paclitaxel; Phosphorylation; Protein Transport; Random Allocation; Sesquiterpenes; Survival Analysis; Xenograft Model Antitumor Assays | 2010 |
A water soluble parthenolide analog suppresses in vivo tumor growth of two tobacco-associated cancers, lung and bladder cancer, by targeting NF-κB and generating reactive oxygen species.
Topics: Animals; Base Sequence; Carcinogens; Cell Cycle; Cell Division; DNA Primers; Electrophoretic Mobility Shift Assay; Flow Cytometry; Lung Neoplasms; Male; Mice; Mice, Nude; NF-kappa B; Nicotiana; Nitrosamines; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Sesquiterpenes; Urinary Bladder Neoplasms | 2011 |
Mixed micelles of PEG(2000)-DSPE and vitamin-E TPGS for concurrent delivery of paclitaxel and parthenolide: enhanced chemosenstization and antitumor efficacy against non-small cell lung cancer (NSCLC) cell lines.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Drug Carriers; Humans; Inhibitory Concentration 50; Lung Neoplasms; Magnetic Resonance Spectroscopy; Micelles; Paclitaxel; Particle Size; Phosphatidylethanolamines; Polyethylene Glycols; Sesquiterpenes; Vitamin E | 2012 |
[Effects of parthenolide on the activity and expression of urokinase type plasminogen activator in PGCL3 cells].
Topics: Actins; Cell Line, Tumor; Cell Proliferation; Humans; Lung Neoplasms; NF-kappa B; Plants, Medicinal; Sesquiterpenes; Tanacetum; Urokinase-Type Plasminogen Activator | 2005 |
Thermosensitization by parthenolide in human lung adenocarcinoma A549 cells and p53- and hsp72-independent apoptosis induction via the nuclear factor-kappaB signal pathway.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Hot Temperature; HSP72 Heat-Shock Proteins; Humans; Lung Neoplasms; NF-kappa B; Sesquiterpenes; Signal Transduction; Tumor Suppressor Protein p53 | 2008 |