parthenolide has been researched along with Colorectal Neoplasms in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 7 (53.85) | 24.3611 |
| 2020's | 4 (30.77) | 2.80 |
| Authors | Studies |
|---|---|
| Abdelhay, ESFW; de Souza, WF; Gehren, AS; Morgado-Diaz, JA; Pires, BRB; Ramos, DAA; Sousa-Squiavinato, ACM | 1 |
| Han, Q; Jin, J; Sun, X; Wang, X; Yang, Y; Yao, W; Yao, X; You, J; Zeng, P; Zhou, J | 1 |
| An, T; Cai, B; Chen, L; Duan, A; Ju, X; Kong, L; Li, X; Li, Y; Yang, Q | 1 |
| Fan, D; Ju, X; Kong, L; Li, Y; Su, G; Yang, Q; Zhang, S; Zhu, Y | 1 |
| Ke, J; Li, X; Liu, B; Lv, X; Yang, H; Zhang, Y | 1 |
| Kang, SB; Kim, DG; Kim, IH; Kim, SH; Kim, SL; Kim, SW; Lee, SO; Lee, ST; Trang, KT | 1 |
| Guo, C; Li, B; Li, Y; Liu, L; Wan, L; Yang, Q; Yu, Q; Zhou, Z | 1 |
| Kim, DG; Kim, IH; Kim, SH; Kim, SL; Kim, SW; Lee, SO; Lee, ST; Trang, KT | 2 |
| Kim, DG; Kim, IH; Kim, SH; Kim, SL; Kim, SW; Lee, SO; Lee, ST; Liu, YC; Park, YR; Seo, SY | 1 |
| Jeong, HJ; Kim, EM; Kim, IH; Kim, SH; Kim, SL; Kim, SW; Kim, YN; Lee, SO; Lee, ST; Liu, YC; Park, YR; Seo, SY | 1 |
| Ong, CN; Shen, HM; Zhang, S | 2 |
13 other study(ies) available for parthenolide and Colorectal Neoplasms
| Article | Year |
|---|---|
Parthenolide inhibits proliferation and invasion, promotes apoptosis, and reverts the cell-cell adhesion loss through downregulation of NF-κB pathway TNF-α-activated in colorectal cancer cells.
Topics: Apoptosis; Caco-2 Cells; Cell Adhesion; Cell Proliferation; Colorectal Neoplasms; Down-Regulation; Humans; NF-kappa B; NF-KappaB Inhibitor alpha; Tumor Necrosis Factor-alpha | 2023 |
[Liposome nanoparticles for targeted delivery of parthenolide induce colorectal cancer necroptosis to ameliorate tumor-infiltrating T cell exhaustion in mice].
Topics: Animals; CD8-Positive T-Lymphocytes; Colorectal Neoplasms; Hepatitis A Virus Cellular Receptor 2; Humans; Liposomes; Mice; Nanoparticles; Necroptosis; T-Cell Exhaustion | 2023 |
Parthenolide inhibits ubiquitin-specific peptidase 7 (USP7), Wnt signaling, and colorectal cancer cell growth.
Topics: 4-Butyrolactone; Apoptosis; beta Catenin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Down-Regulation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Proteolysis; Sesquiterpenes; Ubiquitin-Specific Peptidase 7; Ubiquitination; Wnt Signaling Pathway | 2020 |
USP47 maintains the stemness of colorectal cancer cells and is inhibited by parthenolide.
Topics: Apoptosis; Carcinogenesis; Cell Line, Tumor; Colorectal Neoplasms; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Neoplastic Stem Cells; Prognosis; Protein Binding; Sesquiterpenes; Ubiquitin Thiolesterase; Ubiquitin-Specific Proteases; Up-Regulation | 2021 |
Smad4 re-expression increases the sensitivity to parthenolide in colorectal cancer.
Topics: Animals; Caco-2 Cells; Colorectal Neoplasms; Combined Modality Therapy; Drug Resistance, Neoplasm; Genetic Therapy; HCT116 Cells; HEK293 Cells; HT29 Cells; Humans; Male; Mice; Mice, Inbred C3H; Random Allocation; Sesquiterpenes; Smad4 Protein; Transfection; Xenograft Model Antitumor Assays | 2017 |
Synergistic antitumor effect of 5-fluorouracil in combination with parthenolide in human colorectal cancer.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites, Antineoplastic; Apoptosis; Caspase 3; Caspase 9; Cell Cycle; Cell Line, Tumor; Colorectal Neoplasms; Cytochromes c; Drug Combinations; Drug Resistance, Neoplasm; Drug Synergism; Fluorouracil; Humans; Mice; Mice, Nude; Mitochondria; Neoplasm Transplantation; NF-kappa B; Proto-Oncogene Proteins c-bcl-2; Sesquiterpenes; Xenograft Model Antitumor Assays | 2013 |
Parthenolide from Parthenium integrifolium reduces tumor burden and alleviate cachexia symptoms in the murine CT-26 model of colorectal carcinoma.
Topics: Animals; Antineoplastic Agents, Phytogenic; Asteraceae; Body Weight; Cachexia; Colorectal Neoplasms; Disease Models, Animal; Male; Mice; Mice, Inbred BALB C; Muscle Proteins; Muscle, Skeletal; Neoplasm Transplantation; Organ Size; Phytotherapy; Plant Extracts; Sesquiterpenes; Tripartite Motif Proteins; Tumor Burden; Tumor Necrosis Factor-alpha; Ubiquitin-Protein Ligases | 2013 |
Parthenolide exerts inhibitory effects on angiogenesis through the downregulation of VEGF/VEGFRs in colorectal cancer.
Topics: Cell Movement; Cell Survival; Colorectal Neoplasms; HCT116 Cells; HT29 Cells; Human Umbilical Vein Endothelial Cells; Humans; Neovascularization, Pathologic; Receptors, Vascular Endothelial Growth Factor; Sesquiterpenes; Vascular Endothelial Growth Factor A | 2014 |
Parthenolide enhances sensitivity of colorectal cancer cells to TRAIL by inducing death receptor 5 and promotes TRAIL-induced apoptosis.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Death; Cells, Cultured; Colorectal Neoplasms; Drug Synergism; HCT116 Cells; HT29 Cells; Humans; Receptors, TNF-Related Apoptosis-Inducing Ligand; Sesquiterpenes; TNF-Related Apoptosis-Inducing Ligand; Up-Regulation | 2015 |
Combined Parthenolide and Balsalazide Have Enhanced Antitumor Efficacy Through Blockade of NF-κB Activation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinogenesis; Cell Proliferation; Colitis; Colorectal Neoplasms; Drug Synergism; Female; Humans; Mesalamine; Mice; Mice, Inbred BALB C; NF-kappa B; Phenylhydrazines; Sesquiterpenes; Signal Transduction | 2017 |
Parthenolide suppresses tumor growth in a xenograft model of colorectal cancer cells by inducing mitochondrial dysfunction and apoptosis.
Topics: Apoptosis; Carcinogenesis; Colorectal Neoplasms; Cytochromes c; Genes, bcl-2; HT29 Cells; Humans; Mitochondria; Neovascularization, Pathologic; Sesquiterpenes; Signal Transduction; Xenograft Model Antitumor Assays | 2012 |
Critical roles of intracellular thiols and calcium in parthenolide-induced apoptosis in human colorectal cancer cells.
Topics: Acetylcysteine; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Buthionine Sulfoximine; Calcium; Cell Line, Tumor; Colorectal Neoplasms; Dose-Response Relationship, Drug; Endoplasmic Reticulum Chaperone BiP; Humans; Oxidation-Reduction; Reactive Oxygen Species; Sesquiterpenes; Sulfhydryl Compounds | 2004 |
Involvement of proapoptotic Bcl-2 family members in parthenolide-induced mitochondrial dysfunction and apoptosis.
Topics: Apoptosis; Caspase 8; Caspases; Colorectal Neoplasms; Genes, bcl-2; Humans; Mitochondria; Proto-Oncogene Proteins c-bcl-2; Sesquiterpenes; Signal Transduction; Tanacetum parthenium; Tumor Cells, Cultured; Up-Regulation | 2004 |