parthenolide has been researched along with Cancer of Prostate in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (46.15) | 29.6817 |
| 2010's | 7 (53.85) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bezak, E; Morel, KL; Ormsby, RJ; Sweeney, CJ; Sykes, PJ | 1 |
| Cordes, N; Klebe, S; Morel, KL; Ormsby, RJ; Solly, EL; Sweeney, CJ; Sykes, PJ; Tran, LNK | 1 |
| Bishop, RT; Carrasco, G; Idris, AI; Li, B; Logan, JG; Marino, S | 1 |
| Chaiswing, L; Clair, DK; Clair, WH; Crooks, PA; Fang, F; Holley, AK; Kiningham, KK; Miriyala, S; Noel, T; Oberley, TD; Xu, Y; Zhao, Y | 1 |
| Duhagon, MA; Farrar, WL; Hurt, EM; Kalathur, M; Kawasaki, BT; Kim, YS; Milner, JA | 1 |
| Chin-Sinex, H; Hughes, W; Losch, A; Mendonca, MS; Miller, DA; Sweeney, C; Watson, C | 1 |
| Altuwaijri, S; Bhanot, UK; Chang, C; Chen, L; Deng, F; Gerald, WL; Korets, R; Lal, P; Lilja, HG; Scher, HI; Wenske, S; Zhang, L | 1 |
| Crooks, PA; St Clair, DK; St Clair, WH; Sun, Y; Xu, Y | 1 |
| de las Pozas, A; Parrondo, R; Perez-Stable, C; Rai, P; Reiner, T | 1 |
| Hatashita, M; Hayashi, S; Jujo, Y; Koshiba, K; Sato, T; Shioura, H; Suzuki, R; Tanaka, Y | 1 |
| Bhat-Nakshatri, P; Cheng, L; DeGrado, T; Gokmen-Polar, Y; Hutchins, GD; Jayaprakasan, V; Kelich, S; Miller, KD; Miller, MA; Nakshatri, H; Shanmugam, R; Sledge, GW; Sweeney, CJ; Yip-Schneider, M; Zheng, QH | 1 |
| Crooks, PA; Fang, F; Rangnekar, VM; St Clair, DK; St Clair, WH; Sun, Y; Warren, GW | 1 |
| Berry, PA; Birnie, R; Bryce, SD; Collins, AT; Droop, A; Dussupt, V; Hyde, CF; Lang, SH; Lewis, JL; Maitland, NJ; Roome, C; Stower, MJ | 1 |
13 other study(ies) available for parthenolide and Cancer of Prostate
| Article | Year |
|---|---|
Parthenolide Selectively Sensitizes Prostate Tumor Tissue to Radiotherapy while Protecting Healthy Tissues In Vivo.
Topics: Animals; Antineoplastic Agents; Chemoradiotherapy; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Male; Mice; Mice, Transgenic; Organ Sparing Treatments; Organs at Risk; Prostatic Neoplasms; Radiation Injuries; Radiation Tolerance; Radiation-Sensitizing Agents; Sesquiterpenes; Treatment Outcome | 2017 |
Chronic low dose ethanol induces an aggressive metastatic phenotype in TRAMP mice, which is counteracted by parthenolide.
Topics: Adenocarcinoma; Animals; Disease Progression; Drug Interactions; Ethanol; Female; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplasm Metastasis; Prostatic Neoplasms; Sesquiterpenes | 2018 |
Pharmacological Inhibition of NFκB Reduces Prostate Cancer Related Osteoclastogenesis In Vitro and Osteolysis Ex Vivo.
Topics: Animals; Apoptosis; Cell Adhesion; Cell Line, Tumor; Cell Survival; Coculture Techniques; DNA Fragmentation; Humans; Male; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; NF-kappa B p50 Subunit; Organ Culture Techniques; Osteoblasts; Osteoclasts; Osteogenesis; Prostatic Neoplasms; Rats; Sesquiterpenes; Signal Transduction; X-Ray Microtomography | 2019 |
KEAP1 is a redox sensitive target that arbitrates the opposing radiosensitive effects of parthenolide in normal and cancer cells.
Topics: Animals; Antioxidants; bcl-X Protein; Carrier Proteins; Cell Line; Cell Line, Tumor; Epithelial Cells; Humans; Intracellular Signaling Peptides and Proteins; Kelch-Like ECH-Associated Protein 1; Male; Mice; Mice, Nude; Mitochondrial Proteins; NF-E2-Related Factor 2; Oxidation-Reduction; Oxidative Stress; Phosphoprotein Phosphatases; Prostatic Neoplasms; Radiation Tolerance; Radiation-Sensitizing Agents; Random Allocation; Reactive Oxygen Species; Sesquiterpenes; Thioredoxins; Ubiquitin; Xenograft Model Antitumor Assays | 2013 |
Effects of the sesquiterpene lactone parthenolide on prostate tumor-initiating cells: An integrated molecular profiling approach.
Topics: Animals; Antigens, CD; Cell Line, Tumor; Flow Cytometry; Gene Expression Profiling; Humans; Hyaluronan Receptors; Male; Mice; Neoplasm Proteins; Oligonucleotide Array Sequence Analysis; Prostate; Prostatic Neoplasms; RNA, Neoplasm; Sesquiterpenes; Transcription, Genetic | 2009 |
Suppression of NF-kappaB activity by parthenolide induces X-ray sensitivity through inhibition of split-dose repair in TP53 null prostate cancer cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Cycle; Cell Line, Tumor; Dose-Response Relationship, Radiation; Humans; Male; Models, Biological; NF-kappa B; Prostatic Neoplasms; Radiation Tolerance; RNA, Small Interfering; Sesquiterpenes; Transcription Factor RelA; Tumor Suppressor Protein p53; X-Rays | 2009 |
NF-kappaB regulates androgen receptor expression and prostate cancer growth.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Nude; NF-kappa B; Promoter Regions, Genetic; Prostatic Neoplasms; Receptors, Androgen; Sesquiterpenes; Transcription Factor RelA; Xenograft Model Antitumor Assays | 2009 |
A NADPH oxidase-dependent redox signaling pathway mediates the selective radiosensitization effect of parthenolide in prostate cancer cells.
Topics: Catalase; Cell Line, Tumor; Enzyme Activation; Forkhead Box Protein O3; Forkhead Transcription Factors; Glutathione; Humans; Male; NADPH Oxidases; Oncogene Protein v-akt; Oxidation-Reduction; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphorylation; Prostatic Neoplasms; Radiation-Sensitizing Agents; Sesquiterpenes; Signal Transduction; Superoxide Dismutase; Thioredoxins | 2010 |
NF-kappaB activation enhances cell death by antimitotic drugs in human prostate cancer cells.
Topics: 2-Methoxyestradiol; Antineoplastic Agents; Apoptosis; Base Sequence; Betulinic Acid; Blotting, Western; Cell Line, Tumor; DNA Primers; Docetaxel; Estradiol; Flow Cytometry; Humans; Immunohistochemistry; Male; Mitosis; NF-kappa B; Pentacyclic Triterpenes; Prostatic Neoplasms; Sesquiterpenes; Taxoids; Triterpenes | 2010 |
Thermosensitization and induction of apoptosis or cell-cycle arrest via the MAPK cascade by parthenolide, an NF-κB inhibitor, in human prostate cancer androgen-independent cell lines.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Division; Cell Line, Tumor; Combined Modality Therapy; Extracellular Signal-Regulated MAP Kinases; Flow Cytometry; G2 Phase Cell Cycle Checkpoints; Hot Temperature; Humans; Hyperthermia, Induced; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; NF-kappa B; Prostatic Neoplasms; Sesquiterpenes | 2011 |
Restoring chemotherapy and hormone therapy sensitivity by parthenolide in a xenograft hormone refractory prostate cancer model.
Topics: Androgen Antagonists; Anilides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Bridged-Ring Compounds; Cell Line, Tumor; Docetaxel; Drug Synergism; Endothelium, Vascular; Fibroblast Growth Factor 2; Humans; JNK Mitogen-Activated Protein Kinases; Male; Mice; Mice, Nude; Neovascularization, Pathologic; NF-kappa B; Nitriles; Prostatic Neoplasms; Radionuclide Imaging; Sesquiterpenes; Taxoids; TNF Receptor-Associated Factor 1; TNF Receptor-Associated Factor 2; Tosyl Compounds; Umbilical Veins; Vascular Endothelial Growth Factor A | 2006 |
The radiosensitization effect of parthenolide in prostate cancer cells is mediated by nuclear factor-kappaB inhibition and enhanced by the presence of PTEN.
Topics: Blotting, Western; Electrophoretic Mobility Shift Assay; Gamma Rays; Gene Expression Regulation, Neoplastic; Humans; Male; NF-kappa B; Phosphatidylinositol 3-Kinases; Phosphorylation; Promoter Regions, Genetic; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Radiation Tolerance; Sesquiterpenes; Signal Transduction; Superoxide Dismutase; Tumor Cells, Cultured | 2007 |
Gene expression profiling of human prostate cancer stem cells reveals a pro-inflammatory phenotype and the importance of extracellular matrix interactions.
Topics: Aged; Extracellular Matrix; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Inflammation; Male; Microarray Analysis; Middle Aged; Neoplastic Stem Cells; NF-kappa B; Prostate; Prostatic Neoplasms; Sesquiterpenes | 2008 |