parthenolide has been researched along with Breast Neoplasms in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 13 (43.33) | 29.6817 |
| 2010's | 15 (50.00) | 24.3611 |
| 2020's | 2 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Al-Harrasi, A; Gollahon, LS; Halim, SA; Hussain, F; Khan, A; Khan, ZS; Munir, MT; Rahman, SM; Santos, JM; Sufian, HB; Zahid, MK | 1 |
| Ghorbani-Abdi-Saedabad, A; Hanafi-Bojd, MY; Hoshyar, R; Mollaei, H; Parsamanesh, N; Tayarani-Najaran, Z | 1 |
| Bishop, RT; Idris, AI; Logan, JG; Marino, S; Mollat, P | 1 |
| Enferadi, ST; Jafari, N; Nazeri, S | 1 |
| Altobelli, CR; Berdan, CA; Demeulenaere, SG; Ho, R; Hu, X; Huffman, TR; Lehtola, HS; Maimone, TJ; Nomura, DK; Olzmann, JA; Petri, Y; To, M | 1 |
| Boggs, AE; Charpentier, MS; Martin, SS; Thompson, K; Vitolo, MI; Whipple, RA | 1 |
| Buttitta, G; Carlisi, D; D'Anneo, A; Di Fiore, R; Emanuele, S; Lauricella, M; Tesoriere, G; Vento, R | 1 |
| Carlisi, D; D'Anneo, A; Di Bella, S; Di Fiore, R; Di Marco, P; Emanuele, S; Guercio, A; Lauricella, M; Martinez, R; Puleio, R; Tesoriere, G; Vento, R | 1 |
| Jia, Y; Li, B; Liu, X; Lu, C; Tong, Z; Wang, W | 1 |
| Buttitta, G; Carlisi, D; D'Anneo, A; Di Fiore, R; Emanuele, S; Lauricella, M; Martinez, R; Tesoriere, G; Vento, R | 1 |
| Chen, XY; Chen, Y; Jia, YS; Liu, XD; Lu, C; Tong, ZS; Xu, HJ; Zhou, LY | 1 |
| Buttitta, G; Carlisi, D; D'Anneo, A; di Fiore, R; Emanuele, S; Lauricella, M; Martinez, R; Rolfo, C; Tesoriere, G; Vento, R | 1 |
| Buttitta, G; Carlisi, D; Di Fiore, R; Drago-Ferrante, R; Scerri, C; Tesoriere, G; Vento, R | 1 |
| Diamandis, EP; Paliouras, M | 1 |
| Gach, K; Hrabec, E; Janecka, A; Janecki, T; Koszuk, J; Szemraj, J; Szewczyk, K; Wyrębska, A | 1 |
| Guo, SF; Li, CJ; Shi, TM | 1 |
| Gach, K; Janecka, A; Janecki, T; Koszuk, J; Piekielna, J; Szymański, J; Wyrębska, A | 1 |
| Guo, S; Li, C; Shi, T | 1 |
| Chandrasekar, B; deGraffenried, LA; Donzis, E; Freeman, JW; Friedrichs, WE; Hidalgo, M; Silva, J; Weiss, GR | 1 |
| Lin, ZN; Ong, CN; Shen, HM; Shi, X; Yang, CF; Zhang, S | 1 |
| Bhat-Nakshatri, P; Nakshatri, H; Rice, SE | 1 |
| Bocca, C; Bozzo, F; Gabriel, L; Miglietta, A | 1 |
| Clarke, R; Nehra, R; Riggins, RB; Zwart, A | 1 |
| Badve, S; Campbell, RA; Kumar, S; Mehrotra, S; Murry, DJ; Nakshatri, H; Roman, Y; Sadaria, MR; Sheridan, C; Shortle, NH; Sweeney, CJ | 1 |
| Chen, F; Haley-Zitlin, V; He, G; Huang, G; Kim, HJ; Rushing, JW; Wang, X; Wu, C | 1 |
| Crawford, S; Kraak, MM; Nobert, GS | 1 |
| Bai, J; Gu, P; Margolick, JB; Zhang, H; Zhang, Y; Zhou, J | 1 |
| Du, J; Guo, J; Li, T; Liu, Y; Lu, WL; Wang, GL; Wang, JC; Wu, JW; Zhang, Q; Zhang, X | 1 |
| Bhat-Nakshatri, P; Boswell, SH; Gelfanov, V; Goulet, RJ; Nakshatri, H; Newton, TR; Nozaki, S; Patel, NM; Rice, S; Shortle, NH; Sledge, GW | 1 |
| Nakshatri, H; Nozaki, S; Sledge, GW | 1 |
30 other study(ies) available for parthenolide and Breast Neoplasms
| Article | Year |
|---|---|
Parthenolide reverses the epithelial to mesenchymal transition process in breast cancer by targeting TGFbeta1: In vitro and in silico studies.
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Movement; Epithelial-Mesenchymal Transition; Female; Humans; Molecular Docking Simulation; Sesquiterpenes; Transforming Growth Factor beta1 | 2022 |
Anticancer and apoptotic activities of parthenolide in combination with epirubicin in mda-mb-468 breast cancer cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Epirubicin; Female; Humans; Proto-Oncogene Proteins c-bcl-2; Sesquiterpenes; Topoisomerase II Inhibitors | 2020 |
Pharmacological evidence for the bone-autonomous contribution of the NFκB/β-catenin axis to breast cancer related osteolysis.
Topics: Animals; Apoptosis; beta Catenin; Bone Neoplasms; Breast Neoplasms; Cell Differentiation; Cell Proliferation; Dose-Response Relationship, Drug; Female; Humans; MCF-7 Cells; Mice, Inbred BALB C; Mice, Inbred C57BL; NF-kappa B; Osteoblasts; Osteoclasts; Osteogenesis; Osteolysis; Sesquiterpenes; Signal Transduction; Time Factors | 2017 |
Parthenolide reduces metastasis by inhibition of vimentin expression and induces apoptosis by suppression elongation factor α - 1 expression.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cell Death; Female; Humans; MCF-7 Cells; Peptide Elongation Factor 1; Sesquiterpenes; Tanacetum parthenium; Vimentin | 2018 |
Parthenolide Covalently Targets and Inhibits Focal Adhesion Kinase in Breast Cancer Cells.
Topics: Biological Products; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Female; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Lactones; Sesquiterpenes; Signal Transduction; Tanacetum parthenium | 2019 |
Parthenolide and costunolide reduce microtentacles and tumor cell attachment by selectively targeting detyrosinated tubulin independent from NF-κB inhibition.
Topics: Breast Neoplasms; Cell Line, Tumor; Enzyme Activation; Female; Humans; Microtubules; NF-kappa B; Protein Processing, Post-Translational; Sesquiterpenes; Signal Transduction; Tubulin | 2013 |
Parthenolide induces superoxide anion production by stimulating EGF receptor in MDA-MB-231 breast cancer cells.
Topics: Acetophenones; Acetylcysteine; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Breast Neoplasms; Cell Line, Tumor; Enzyme Inhibitors; ErbB Receptors; Female; Humans; NADPH Oxidases; NF-kappa B; Phosphorylation; Protein Tyrosine Phosphatases; Quinazolines; Sesquiterpenes; Superoxides; Tyrphostins | 2013 |
Parthenolide generates reactive oxygen species and autophagy in MDA-MB231 cells. A soluble parthenolide analogue inhibits tumour growth and metastasis in a xenograft model of breast cancer.
Topics: Animals; Autophagy; Breast Neoplasms; Calcium; CASP8 and FADD-Like Apoptosis Regulating Protein; Cell Line, Tumor; Cell Survival; Fas-Associated Death Domain Protein; Female; Humans; Membrane Potential, Mitochondrial; Mice; NF-kappa B; Nuclear Pore Complex Proteins; Reactive Oxygen Species; RNA-Binding Proteins; Sesquiterpenes; Xenograft Model Antitumor Assays | 2013 |
Inhibition of AMPK/autophagy potentiates parthenolide-induced apoptosis in human breast cancer cells.
Topics: AMP-Activated Protein Kinases; Apoptosis; Autophagy; Breast Neoplasms; Cell Cycle Checkpoints; Female; Humans; MCF-7 Cells; Reactive Oxygen Species; Sesquiterpenes | 2014 |
The oxygen radicals involved in the toxicity induced by parthenolide in MDA-MB-231 cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Female; Humans; Hydrogen Peroxide; Mitochondria; NADPH Oxidases; Sesquiterpenes; Superoxide Dismutase; Superoxide Dismutase-1; Superoxides | 2014 |
RIP3 overexpression sensitizes human breast cancer cells to parthenolide in vitro via intracellular ROS accumulation.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; Breast; Breast Neoplasms; Cell Line, Tumor; Female; Gene Deletion; Gene Expression Regulation, Neoplastic; Humans; Reactive Oxygen Species; Receptor-Interacting Protein Serine-Threonine Kinases; Sesquiterpenes; Up-Regulation | 2014 |
The synergistic effect of SAHA and parthenolide in MDA-MB231 breast cancer cells.
Topics: Apoptosis; Autophagy; Breast Neoplasms; Cell Line, Tumor; Down-Regulation; Drug Synergism; Female; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; NF-kappa B; Sesquiterpenes; Vorinostat | 2015 |
Parthenolide and DMAPT exert cytotoxic effects on breast cancer stem-like cells by inducing oxidative stress, mitochondrial dysfunction and necrosis.
Topics: Acetophenones; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Female; Fluorescent Dyes; Humans; Membrane Potential, Mitochondrial; Mitochondria; NADPH Oxidases; Neoplastic Stem Cells; NF-E2-Related Factor 2; Oligopeptides; Onium Compounds; Oxidative Stress; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Sesquiterpenes; Transcription Factors | 2016 |
Intracellular signaling pathways regulate hormone-dependent kallikrein gene expression.
Topics: Androgens; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Extracellular Signal-Regulated MAP Kinases; Female; Gene Expression Regulation, Neoplastic; Humans; Kallikreins; MAP Kinase Kinase Kinases; NF-kappa B; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Prostate-Specific Antigen; Proto-Oncogene Proteins c-myc; Receptors, Androgen; Serine Endopeptidases; Sesquiterpenes; Signal Transduction; Transcriptional Activation | 2008 |
Comparison of anti-invasive activity of parthenolide and 3-isopropyl-2-methyl-4-methyleneisoxazolidin-5-one (MZ-6)--a new compound with α-methylene-γ-lactone motif--on two breast cancer cell lines.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Survival; Female; Humans; Isoxazoles; Lactones; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Sesquiterpenes; Urokinase-Type Plasminogen Activator | 2012 |
Culture supernatants of breast cancer cell line MDA-MB-231 treated with parthenolide inhibit the proliferation, migration, and lumen formation capacity of human umbilical vein endothelial cells.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Human Umbilical Vein Endothelial Cells; Humans; Interleukin-8; Matrix Metalloproteinase 9; Sesquiterpenes; Vascular Endothelial Growth Factor A | 2012 |
Apoptosis-mediated cytotoxic effects of parthenolide and the new synthetic analog MZ-6 on two breast cancer cell lines.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Cell Cycle Checkpoints; Cell Proliferation; Cell Shape; DNA Replication; Drug Screening Assays, Antitumor; Female; Humans; Isoxazoles; Lipid Peroxidation; MCF-7 Cells; Oxidative Stress; Sesquiterpenes; Transcription, Genetic | 2013 |
Role of NF-κB activation in matrix metalloproteinase 9, vascular endothelial growth factor and interleukin 8 expression and secretion in human breast cancer cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Breast Neoplasms; Cell Line, Tumor; DNA; Electrophoretic Mobility Shift Assay; Female; Gene Expression; Humans; Interleukin-8; Matrix Metalloproteinase 9; NF-kappa B; Protein Binding; Sesquiterpenes; Vascular Endothelial Growth Factor A | 2013 |
NF-kappa B inhibition markedly enhances sensitivity of resistant breast cancer tumor cells to tamoxifen.
Topics: Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Humans; I-kappa B Proteins; NF-kappa B; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Sesquiterpenes; Signal Transduction; Tamoxifen | 2004 |
Suppressed NF-kappaB and sustained JNK activation contribute to the sensitization effect of parthenolide to TNF-alpha-induced apoptosis in human cancer cells.
Topics: Apoptosis; Breast Neoplasms; Cell Line, Tumor; Enzyme Activation; Female; Humans; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; NF-kappa B; Sesquiterpenes; Tumor Necrosis Factor-alpha | 2004 |
Antitumor agent parthenolide reverses resistance of breast cancer cells to tumor necrosis factor-related apoptosis-inducing ligand through sustained activation of c-Jun N-terminal kinase.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis Regulatory Proteins; Breast Neoplasms; Cell Division; Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Fibroblasts; Humans; JNK Mitogen-Activated Protein Kinases; Membrane Glycoproteins; Mice; Mice, Knockout; Mitogen-Activated Protein Kinases; NF-kappa B; Oxidative Stress; Sesquiterpenes; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha | 2004 |
Microtubule-interfering activity of parthenolide.
Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Colchicine; Cytoskeleton; Dose-Response Relationship, Drug; Female; Humans; Microscopy, Electron; Microscopy, Fluorescence; Microtubules; Paclitaxel; Plant Extracts; Sesquiterpenes; Tanacetum parthenium; Tubulin | 2004 |
The nuclear factor kappa B inhibitor parthenolide restores ICI 182,780 (Faslodex; fulvestrant)-induced apoptosis in antiestrogen-resistant breast cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Division; Cell Line, Tumor; Drug Resistance, Neoplasm; Estradiol; Estrogen Receptor Modulators; Female; Fulvestrant; Humans; NF-kappa B; Sesquiterpenes | 2005 |
The sesquiterpene lactone parthenolide in combination with docetaxel reduces metastasis and improves survival in a xenograft model of breast cancer.
Topics: Adipocytes; Animals; Breast Neoplasms; Cell Death; Cell Line, Tumor; Disease Models, Animal; Docetaxel; Humans; Interferon-gamma; Interleukin-6; Interleukin-8; Lactones; Mice; Mice, Nude; Neoplasm Metastasis; Sesquiterpenes; Survival Rate; Taxoids; Tumor Necrosis Factor-alpha; Xenograft Model Antitumor Assays | 2005 |
Antiproliferative activities of parthenolide and golden feverfew extract against three human cancer cell lines.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apigenin; Breast Neoplasms; Camphor; Cell Division; Cell Line, Tumor; Drug Synergism; Female; Humans; Luteolin; Neoplasms; Plant Extracts; Sesquiterpenes; Tanacetum parthenium; Uterine Cervical Neoplasms | 2006 |
Estrogen dependent growth inhibitory effects of tamoxifen but not genistein in solid tumors derived from estrogen receptor positive (ER+) primary breast carcinoma MCF7: single agent and novel combined treatment approaches.
Topics: Anticarcinogenic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Estradiol; Female; Genistein; Humans; Neoplasms, Hormone-Dependent; Receptors, Estrogen; Sesquiterpenes; Spheroids, Cellular; Tamoxifen; Tretinoin | 2006 |
NF-kappaB pathway inhibitors preferentially inhibit breast cancer stem-like cells.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Ditiocarb; Female; Humans; Mice; Mice, Nude; Neoplastic Stem Cells; NF-kappa B; Paclitaxel; Pyrrolidines; Sesquiterpenes; Spheroids, Cellular; Thiocarbamates; Time Factors; Xenograft Model Antitumor Assays | 2008 |
A potential target associated with both cancer and cancer stem cells: a combination therapy for eradication of breast cancer using vinorelbine stealthy liposomes plus parthenolide stealthy liposomes.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Drug Compounding; Female; Humans; Lipids; Liposomes; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplastic Stem Cells; Sesquiterpenes; Technology, Pharmaceutical; Time Factors; Vinblastine; Vinorelbine; Xenograft Model Antitumor Assays | 2008 |
Paclitaxel sensitivity of breast cancer cells with constitutively active NF-kappaB is enhanced by IkappaBalpha super-repressor and parthenolide.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Northern; Blotting, Western; Breast Neoplasms; Caenorhabditis elegans Proteins; DNA; DNA-Binding Proteins; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Humans; I-kappa B Proteins; Inhibitor of Apoptosis Proteins; NF-kappa B; NF-KappaB Inhibitor alpha; Paclitaxel; Plants, Medicinal; Protein Binding; Proteins; Repressor Proteins; Sesquiterpenes; Superoxide Dismutase; TNF Receptor-Associated Factor 1; Tumor Cells, Cultured | 2000 |
Repression of GADD153/CHOP by NF-kappaB: a possible cellular defense against endoplasmic reticulum stress-induced cell death.
Topics: Animals; Apoptosis; Breast Neoplasms; Calcimycin; CCAAT-Enhancer-Binding Proteins; Endoplasmic Reticulum; Fibroblasts; Gene Expression Regulation, Neoplastic; Humans; Ionophores; Mice; NF-kappa B; Sesquiterpenes; Stress, Physiological; Transcription Factor CHOP; Transcription Factors; Transfection; Tumor Cells, Cultured; Tunicamycin | 2001 |