paroxetine has been researched along with Pregnancy in 140 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (0.71) | 18.7374 |
1990's | 20 (14.29) | 18.2507 |
2000's | 66 (47.14) | 29.6817 |
2010's | 44 (31.43) | 24.3611 |
2020's | 9 (6.43) | 2.80 |
Authors | Studies |
---|---|
Alexandre, C; Alexandre, J; Desaunay, P; Dreyfus, M; Eude, LG; Fedrizzi, S; Guénolé, F; Uguz, F | 1 |
Breur, JMPJ; Leerssen, ECM; Tak, RO | 1 |
Doucet, N; Hudon Thibeault, AA; López de Los Santos, Y; Sanderson, JT; Vaillancourt, C | 1 |
Aucott, L; Fitton, CA; Fleming, M; Mackay, DF; McLay, JS; Pell, JP; Steiner, MFC | 1 |
Baryshnikova, E; Bellissima, V; Gabriella Tina, L; Gavilanes, D; Gazzolo, D; Godos, J; Nigro, F; Pluchinotta, F; Varrica, A; Ververs, T; Visser, GHA | 1 |
Akazawa, M; Ishikawa, T; Kikuchi, S; Kobayashi, N; Kuriyama, S; Mano, N; Miyakoda, K; Nishigori, H; Obara, T; Tomita, H; Yaegashi, N | 1 |
Cabrera, RM; Kim, J; Law, E; Linda Lin, Y; Wlodarczyk, BJ | 1 |
Esposito, DB; Petersen, JM; Werler, MM | 1 |
Reimers, A; Reis, M; Svensson, M | 1 |
Almurjan, A; Badhan, RKS; Macfarlane, H | 1 |
Brekke, M; Molden, E; Skogvoll, E; Spigset, O; Westin, AA | 1 |
Agius, M; Ripullone, K; Womersley, K | 1 |
Bewley, S; Braillon, A | 1 |
Bassi, M; Cauli, G; Gala, C; Iapichino, E; Marconi, AM; Quartieri Bollani, M; Rucci, P | 1 |
Clinton, SM; Glover, ME; Jackson, NL; McCoy, CR; Shupe, EA; Unroe, KA | 1 |
Bonsel, GJ; Lambregtse-van den Berg, MP; Molenaar, NM | 1 |
Hebert, MF; Hu, T; Wang, J; Zha, W | 1 |
Fujii, T; Hori, S; Matsuoka, S; Nagai, M; Ohtani, H; Satoh, H; Sawada, Y; Taketani, Y | 1 |
Blackwell, KA; Forray, A; Glover, J; Yonkers, KA | 1 |
Aydin, B; Beken, S; Dilli, D; Dinlen, N; Okumuş, N; Zenciroğlu, A | 1 |
Herings, RM; Houweling, LM; Ruiter, R; Straus, SM; Stricker, BH; Zomerdijk, IM | 1 |
Akil, H; Clinton, SM; Cohen, JL; Fant, AD; Glover, ME; Jackson, NL; Pugh, PC | 1 |
Bérard, A; Boukhris, T; Chaabane, S; Iessa, N; Muanda, FT; Zhao, JP | 1 |
Bérard, A; Boukhris, T; Chaabane, S; Muanda, FT; Zhao, J | 1 |
Arpaci, N; Uguz, F | 1 |
Avgil, M; Clementi, M; Di Gianantonio, E; Diav-Citrin, O; Ornoy, A; Schaefer, C; Shechtman, S; Wajnberg, R; Weber-Schoendorfer, C; Weinbaum, D | 1 |
Einarson, A; Einarson, TR; Koren, G; O'Brien, L; Sarkar, M | 1 |
Jureidini, J; Mintzes, B | 1 |
Ham, BJ; Han, C; Marks, DM; Masand, PS; Pae, CU; Park, MH; Patkar, AA | 1 |
Kennedy, D | 1 |
Bellantuono, C; Gentile, S | 1 |
Davidson, S; Gil-Ad, I; Harell, D; Maayan, R; Prokonov, D; Taler, M; Weizman, A | 1 |
Freeman, MP | 1 |
Lanza di Scalea, T; Wisner, KL | 1 |
Berant, M; Birk, E; Klinger, G; Linder, N; Merlob, P; Sirota, L; Stahl, B | 1 |
Ephross, SA; Olshan, AF; Poole, C; Wurst, KE | 1 |
Belitser, SV; Egberts, TC; Schobben, AF; Ververs, FF; Visser, GH; Voorbij, HA; Zwarts, P | 1 |
Einarson, A | 4 |
Tanne, JH | 1 |
Bakker, MK; Buys, CH; de Jong-van den Berg, LT; de Walle, HE; Kerstjens-Frederikse, WS | 1 |
Bérard, A | 1 |
Scialli, AR | 1 |
Ellfolk, M; Malm, H | 1 |
Brocco, M; Cremers, TI; de Jong, TR; de Nanteuil, G; Dekeyne, A; Di Cara, B; Flik, G; Gobert, A; Lejeune, F; Mannoury la Cour, C; Millan, MJ; Olivier, B; Rivet, JM | 1 |
Favrelière, S; Jaafari, N; Nourrisson, A; Pérault Pochat, MC | 1 |
Bérard, A; Broy, P; Nakhai-Pour, HR | 1 |
Einarson, A; Koren, G | 3 |
Antonioli, L; Blandizzi, C; Colucci, R; Corona, T; Fornai, M; Mantarro, S; Montagnani, S; Pergola, A; Ruggiero, E; Scollo, C; Testi, A; Tuccori, M | 1 |
Aitchison, KJ; Keers, R | 1 |
Aoun, J; Gorsane, MA; Krebs, MO; Soufia, M | 1 |
Koren, G | 1 |
Beste, J; Blackwell, JC; Patel, BN | 1 |
Artama, M; Gissler, M; Malm, H; Ritvanen, A | 1 |
Akulova, VK; Fedotova, YO; Ordian, NÉ; Pivina, SG | 1 |
Bozzo, P; Koren, G; Pupco, A | 1 |
Gilbert, AL; Grzeskowiak, LE; Morrison, JL | 1 |
Einarson, A; Puryear, LJ; Spinelli, M | 1 |
Evans, S; Gilbert, R; Nazareth, I; Petersen, I | 1 |
Bérard, A; De Vera, MA | 1 |
Dilillo, D; Penagini, F; Pogliani, L; Schneider, L; Zuccotti, GV | 1 |
Bérard, A; Crespin, S; Damase-Michel, C; Sheehy, O | 1 |
Coffey, DB; John, N; Potter, PO | 1 |
Byatt, N; Deligiannidis, KM; Freeman, MP | 1 |
Isoherranen, N; Ke, AB; Nallani, SC; Rostami-Hodjegan, A; Unadkat, JD; Zhao, P | 1 |
Costei, AM; Ho, T; Ito, S; Koren, G; Kozer, E | 1 |
Kelly, PA; McBean, DE; Olverman, HJ; Quate, L; Ritchie, IM | 1 |
Chilton, AP; Elias, E; Hubscher, SG; Milkiewicz, P | 1 |
Chiu, CC; Huang, SY; Shen, WW; Su, KP | 1 |
Altshuler, LL; Haynes, D; Hendrick, V; Hwang, S; Lee, E; Stowe, ZN | 1 |
Pham, B; Pryse-Phillips, W; Yuen, DE | 1 |
Coombs, RC; Isbister, GK; Jaiswal, S | 1 |
Newport, DJ; Stowe, ZN | 1 |
Dahlem, P; Duijvestijn, YC; Kalmeijer, MD; Passier, AL; Smiers, F | 1 |
Sari, Y; Zhou, FC | 1 |
Battaglia, G; Carrasco, GA; Chen, Z; Landry, M; Van de Kar, LD; Waimey, K | 1 |
Batash, D; Bulkowstein, M; Heyman, E; Keidar, R; Morag, I | 1 |
Sari, Y; Xu, Y; Zhou, FC | 1 |
Aamo, TO; Berle, JØ; Breilid, H; Spigset, O; Steen, VM; Zahlsen, K | 1 |
Bertilsson, L; Kytölä, J; Laine, K | 1 |
Battaglia, G; Carrasco, GA; Chen, Z; Muma, NA; Shankaran, M; Sripathirathan, K; Tetzlaff, J; Van De Kar, LD | 1 |
Clarke, P; Haddad, PM; Pal, BR; Sridhiran, S; Wieck, A | 1 |
Stiskal, JA | 2 |
Hashimoto, K | 1 |
Williams, M; Wooltorton, E | 1 |
Källén, B; Otterblad Olausson, P | 1 |
Knoppert, DC; Nimkar, R; Principi, T; Yuen, D | 1 |
McClendon, J | 1 |
Cuzzell, JZ | 1 |
Hallberg, P; Odlind, V; Sjöblom, V | 1 |
de Jong-van den Berg, L; Egberts, T; Kaasenbrood, H; Schobben, F; Ververs, T; Visser, G | 1 |
Thormahlen, GM | 1 |
Einarson, A; Wood, W | 1 |
Bérard, A; Blais, L; Oraichi, D; Ramos, E; Rey, E; St-André, M | 1 |
Ahmed, M; Parameshwaran, A; Swamy, P | 1 |
de la Rosa M, A; De Las Cuevas, C; Sanz, EJ; Troyano, JM | 1 |
Entsuah, R; Mangano, R; Pollack, M; Simon, NM; Tzanis, E; Zhang, Y | 1 |
Blanco, CE; Desbonnet, L; Leonard, BE; Myint, AM; Prickaerts, J; Scheepens, A; Steinbusch, HW; Van den Hove, DL | 1 |
Bar-Oz, B; Bérard, A; Boskovic, R; Einarson, A; Einarson, T; Koren, G; Malm, H; O'Brien, L | 1 |
Cole, JA; Cosmatos, IS; Ephross, SA; Walker, AM | 1 |
Bakker, MK; de Jong van den Berg, LT; de Walle, HE; Kölling, P; van den Berg, PB | 1 |
Burbeck, R; McDonald, L; Pilling, S; Tomson, D | 1 |
DeSantis, M; Einarson, A; Einarson, TR; Kennedy, D; Koren, G; Malm, H; Panchaud, A; Paulus, WD; Pistelli, A | 1 |
González, MI; Leret, ML; Molina-Holgado, E; Molina-Holgado, F; Reader, TA | 1 |
Kelly, PA; McBean, DE; Ritchie, IM; Sharkey, J | 1 |
Ganapathy, V; Leibach, FH; Mahesh, VB; Prasad, PD | 1 |
Caldecott-Hazard, S; Weissman, AD | 1 |
Barnes, GA; McCook, EC; Seidler, FJ; Slotkin, TA | 1 |
Ahlner, J; Dahl, ML; Olhager, E | 1 |
Kamei, K; Kitera, K; Mikuni, M; Muneoka, K; Ogawa, T; Takahashi, K; Takigawa, M | 1 |
Brochu, J; Cook, L; Feldkamp, M; Koren, G; Kulin, NA; Matsui, D; Ormond, K; Pastuszak, A; Rieder, M; Sage, SR; Schick-Boschetto, B; Spivey, G; Stein-Schechman, AK | 1 |
Grush, LR | 1 |
McReynolds, AM; Meyer, JS | 1 |
McReynolds, AM; Meyer, JS; Shearman, LP; Zhou, FC | 1 |
Kristensen, AS; Mortensen, OV; Rudnick, G; Wiborg, O | 1 |
Lamberg, L | 1 |
Christensen, HD; Coleman, FH; Gonzalez, CL; Rayburn, WF | 1 |
Cohen, LS; Hostetter, A; Nemeroff, CB; Owens, MJ; Ritchie, JC; Stowe, ZN | 1 |
Hostetter, A; Llewellyn, A; McLaughlin, E; Stowe, ZN; Strader, JR | 1 |
Hagino, Y; Kodama, Y; Nonaka, R; Watanabe, M | 1 |
Friedman, EH | 1 |
Kamei, K; Kato, H; Mimura, Y; Muneoka, K; Ogawa, T; Takigawa, M | 1 |
Bosschaart, AN; Kok-Van Rooij, GW; Nijhuis, IJ | 1 |
Einarson, A; Koren, G; Selby, P | 1 |
Raines, KW; Seidler, FJ; Slotkin, TA | 1 |
Ali, SF; Seidler, FJ; Slikker, W; Slotkin, TA; Xu, Z | 1 |
Bell, J; Whitaker-Azmitia, PM; Zhang, XN | 1 |
Akbari, HM; Azmitia, EC; Kramer, HK; Spear, LP; Whitaker-Azmitia, PM | 1 |
Cool, DR; Ganapathy, V; Leibach, FH | 1 |
Cool, DR; Ganapathy, V; Liebach, FH | 1 |
Quartermain, D; Shemer, AV; Whitaker-Azmitia, PM | 1 |
Baldwin, JA; Davidson, EJ; Pritchard, AL; Ridings, JE | 1 |
21 review(s) available for paroxetine and Pregnancy
Article | Year |
---|---|
Benefits and Risks of Antidepressant Drugs During Pregnancy: A Systematic Review of Meta-analyses.
Topics: Antidepressive Agents; Child; Female; Fluoxetine; Humans; Infant, Newborn; Paroxetine; Pregnancy; Premature Birth; Risk Assessment; Sertraline | 2023 |
In utero exposure to antidepressant medication and neonatal and child outcomes: a systematic review.
Topics: Antidepressive Agents; Attention Deficit Disorder with Hyperactivity; Autism Spectrum Disorder; Child; Conduct Disorder; Congenital Abnormalities; Depressive Disorder; Female; Gestational Age; Heart Defects, Congenital; Humans; Infant, Newborn; Neurodevelopmental Disorders; Paroxetine; Pregnancy; Pregnancy Complications; Premature Birth; Prenatal Exposure Delayed Effects; Risk Factors | 2020 |
What are the risks associated with different Selective Serotonin Re-uptake Inhibitors (SSRIs) to treat depression and anxiety in pregnancy? An evaluation of current evidence.
Topics: Adult; Anxiety; Citalopram; Depression; Female; Humans; Paroxetine; Pregnancy; Pregnancy Complications; Selective Serotonin Reuptake Inhibitors; Serotonin | 2017 |
Antidepressant use in pregnant and postpartum women.
Topics: Antidepressive Agents; Depression, Postpartum; Depressive Disorder; Female; Heart Defects, Congenital; Humans; Infant, Newborn; Paroxetine; Persistent Fetal Circulation Syndrome; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects | 2014 |
The risk of major cardiac malformations associated with paroxetine use during the first trimester of pregnancy: a systematic review and meta-analysis.
Topics: Abnormalities, Drug-Induced; Female; Heart Defects, Congenital; Humans; Maternal Exposure; Paroxetine; Pregnancy; Pregnancy Trimester, First; Risk Assessment; Selective Serotonin Reuptake Inhibitors | 2016 |
Does paroxetine cause cardiac malformations?
Topics: Case-Control Studies; Cohort Studies; Drug-Related Side Effects and Adverse Reactions; Female; Heart Defects, Congenital; Humans; Paroxetine; Pregnancy; Pregnancy Trimester, First; Selective Serotonin Reuptake Inhibitors | 2008 |
Paroxetine: safety and tolerability issues.
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Child; Clinical Trials as Topic; Delayed-Action Preparations; Drug Interactions; Female; Humans; Mental Disorders; Paroxetine; Pregnancy; Selective Serotonin Reuptake Inhibitors | 2008 |
Selective serotonin reuptake inhibitor exposure during early pregnancy and the risk of fetal major malformations: focus on paroxetine.
Topics: Abnormalities, Drug-Induced; Antidepressive Agents, Second-Generation; Controlled Clinical Trials as Topic; Cross-Sectional Studies; Depressive Disorder; Female; Humans; Infant, Newborn; Paroxetine; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Prospective Studies; Risk; Selective Serotonin Reuptake Inhibitors | 2009 |
Antidepressant medication use during breastfeeding.
Topics: Antidepressive Agents, Second-Generation; Breast Feeding; Citalopram; Depression, Postpartum; Female; Fluoxetine; Humans; Infant; Lactation; Paroxetine; Pregnancy; Selective Serotonin Reuptake Inhibitors; Sertraline | 2009 |
First trimester paroxetine use and the prevalence of congenital, specifically cardiac, defects: a meta-analysis of epidemiological studies.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Female; Heart Defects, Congenital; Humans; Odds Ratio; Paroxetine; Pregnancy; Pregnancy Trimester, First; Selective Serotonin Reuptake Inhibitors | 2010 |
Risks associated with in utero and lactation exposure to selective serotonin reuptake inhibitors (SSRIs).
Topics: Adult; Breast Feeding; Cardiovascular Abnormalities; Congenital Abnormalities; Female; Fluoxetine; Humans; Hypertension, Pulmonary; Infant, Newborn; Lactation; Maternal Exposure; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; PubMed; Respiratory Distress Syndrome, Newborn; Risk Assessment; Selective Serotonin Reuptake Inhibitors | 2010 |
[Treatment of depressed pregnant women by selective serotonin reuptake inhibitors: risk for the foetus and the newborn].
Topics: Abnormalities, Drug-Induced; Antidepressive Agents, Second-Generation; Depressive Disorder; Female; Gestational Age; Humans; Infant, Newborn; Paroxetine; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Risk; Secondary Prevention; Selective Serotonin Reuptake Inhibitors | 2010 |
Use of selective serotonin reuptake inhibitors during pregnancy and risk of major and cardiovascular malformations: an update.
Topics: Abnormalities, Drug-Induced; Cardiovascular Abnormalities; Citalopram; Depression; Female; Fluoxetine; Fluvoxamine; Humans; Maternal-Fetal Exchange; Paroxetine; Pregnancy; Pregnancy Complications; Selective Serotonin Reuptake Inhibitors; Sertraline; Teratogens | 2010 |
Gender differences in antidepressant drug response.
Topics: Abnormalities, Drug-Induced; Antidepressive Agents; Antidepressive Agents, Tricyclic; Depression, Postpartum; Depressive Disorder; Drug Tolerance; Female; Humans; Male; Milk, Human; Paroxetine; Pregnancy; Prevalence; Risk Factors; Selective Serotonin Reuptake Inhibitors; Sex Factors; Treatment Outcome; Women | 2010 |
[SSRIs and pregnancy: a review of the literature].
Topics: Abnormalities, Drug-Induced; Antidepressive Agents; Depressive Disorder, Major; Drug-Related Side Effects and Adverse Reactions; Female; Heart Defects, Congenital; Humans; Infant, Newborn; Infant, Newborn, Diseases; Paroxetine; Pregnancy; Pregnancy Complications; Pregnancy Trimester, Third; Risk Assessment; Selective Serotonin Reuptake Inhibitors | 2010 |
Investigating outcomes following the use of selective serotonin reuptake inhibitors for treating depression in pregnancy: a focus on methodological issues.
Topics: Depressive Disorder; Female; Humans; Paroxetine; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Selective Serotonin Reuptake Inhibitors; Treatment Outcome | 2011 |
Publishing statistically significant results with questionable clinical importance: focus on antidepressant use in pregnancy.
Topics: Abnormalities, Drug-Induced; Antidepressive Agents; Bias; Causality; Compensation and Redress; Cross-Sectional Studies; Data Interpretation, Statistical; Depressive Disorder; Drug Utilization; Female; Heart Defects, Congenital; Humans; Infant, Newborn; Paroxetine; Preconception Care; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Product Surveillance, Postmarketing; Publishing; Risk Factors; Selective Serotonin Reuptake Inhibitors | 2012 |
Antidepressant use in pregnancy: a critical review focused on risks and controversies.
Topics: Abnormalities, Drug-Induced; Antidepressive Agents; Depressive Disorder; Female; Humans; Infant, Newborn; Paroxetine; Persistent Fetal Circulation Syndrome; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Prenatal Exposure Delayed Effects; Risk Factors; Selective Serotonin Reuptake Inhibitors | 2013 |
Clinical management of perinatal depression: focus on paroxetine.
Topics: Adult; Antidepressive Agents, Second-Generation; Depression, Postpartum; Female; Fetus; Humans; Infant, Newborn; Paroxetine; Pregnancy; Pregnancy Complications; Selective Serotonin Reuptake Inhibitors | 2003 |
Paroxetine use during pregnancy: is it safe?
Topics: Female; Humans; Infant, Newborn; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Risk Factors | 2006 |
Paroxetine and congenital malformations: meta-Analysis and consideration of potential confounding factors.
Topics: Abnormalities, Drug-Induced; Adult; Amniocentesis; Antidepressive Agents, Second-Generation; Anxiety; Depression; Electrocardiography; Female; Humans; Infant, Newborn; Paroxetine; Pregnancy; Pregnancy Complications; Pregnancy Trimesters; Ultrasonography | 2007 |
3 trial(s) available for paroxetine and Pregnancy
Article | Year |
---|---|
Promoting the well-being of mothers with multidisciplinary psychosocial interventions in the perinatal period.
Topics: Adult; Antidepressive Agents; Anxiety; Combined Modality Therapy; Depression; Depression, Postpartum; Female; Humans; Longitudinal Studies; Mothers; Paroxetine; Patient Acceptance of Health Care; Perinatal Care; Pregnancy; Pregnancy Complications; Psychotherapy; Risk Factors; Sertraline; Treatment Outcome | 2019 |
Effect of cytochrome P450 2D6 genotype on maternal paroxetine plasma concentrations during pregnancy.
Topics: Adult; Antidepressive Agents, Second-Generation; Cohort Studies; Cytochrome P-450 CYP2D6; Depression; Drug Monitoring; Female; Genotype; Humans; Middle Aged; Paroxetine; Pharmacogenetics; Pregnancy; Surveys and Questionnaires; Treatment Outcome; Young Adult | 2009 |
A randomized controlled trial of venlafaxine ER and paroxetine in the treatment of outpatients with panic disorder.
Topics: Abortion, Spontaneous; Administration, Oral; Adult; Affective Disorders, Psychotic; Cyclohexanols; Delayed-Action Preparations; Diagnostic and Statistical Manual of Mental Disorders; Diarrhea; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Outpatients; Panic Disorder; Paroxetine; Pregnancy; Pregnancy, Unplanned; Remission Induction; Selective Serotonin Reuptake Inhibitors; Time Factors; Treatment Outcome; Venlafaxine Hydrochloride | 2007 |
116 other study(ies) available for paroxetine and Pregnancy
Article | Year |
---|---|
Severe transient neonatal long QT syndrome due to maternal paroxetine usage: a case report.
Topics: Electrocardiography; Female; Humans; Infant, Newborn; Long QT Syndrome; Maternal Exposure; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index | 2019 |
Serotonin and serotonin reuptake inhibitors alter placental aromatase.
Topics: Aromatase; Cells, Cultured; Citalopram; Female; Fluoxetine; Humans; Molecular Docking Simulation; Paroxetine; Placenta; Pregnancy; Selective Serotonin Reuptake Inhibitors; Serotonin; Sertraline; Trophoblasts; Venlafaxine Hydrochloride | 2019 |
Antenatal maternal antidepressants drugs treatment affects S100B levels in maternal-fetal biological fluids in a dose dependent manner.
Topics: Adult; Amniotic Fluid; Antidepressive Agents; Biomarkers; Central Nervous System Diseases; Clinical Laboratory Techniques; Cross-Sectional Studies; Dose-Response Relationship, Drug; Female; Humans; Maternal-Fetal Relations; Paroxetine; Pregnancy; S100 Calcium Binding Protein beta Subunit | 2020 |
Antidepressant prescriptions for prenatal and postpartum women in Japan: A health administrative database study.
Topics: Antidepressive Agents; Female; Humans; Japan; Paroxetine; Postpartum Period; Pregnancy; Selective Serotonin Reuptake Inhibitors | 2020 |
The teratogenic effects of sertraline in mice.
Topics: Animals; Citalopram; Female; Humans; Mice; Mice, Inbred ICR; Paroxetine; Pregnancy; Selective Serotonin Reuptake Inhibitors; Sertraline | 2020 |
Selective serotonin reuptake inhibitor use patterns among commercially insured US pregnancies (2005-2014).
Topics: Adolescent; Adult; Cohort Studies; Female; Humans; Middle Aged; Paroxetine; Pregnancy; Pregnancy Trimesters; Selective Serotonin Reuptake Inhibitors; Sertraline; Young Adult | 2021 |
[Pharmacokinetics of antidepressants during pregnancy].
Topics: Antidepressive Agents; Cytochrome P-450 CYP2D6; Female; Fluoxetine; Humans; Paroxetine; Pregnancy; Pregnancy Complications; Selective Serotonin Reuptake Inhibitors | 2020 |
Precision dosing-based optimisation of paroxetine during pregnancy for poor and ultrarapid CYP2D6 metabolisers: a virtual clinical trial pharmacokinetics study.
Topics: Adult; Computer Simulation; Cytochrome P-450 CYP2D6; Drug Dosage Calculations; Female; Humans; Middle Aged; Models, Biological; Paroxetine; Pharmacogenomic Variants; Phenotype; Pregnancy; Pregnancy Trimesters; Selective Serotonin Reuptake Inhibitors | 2020 |
Selective serotonin reuptake inhibitors and venlafaxine in pregnancy: Changes in drug disposition.
Topics: Adult; Antidepressive Agents; Citalopram; Databases, Factual; Depressive Disorder; Drug Monitoring; Female; Fluvoxamine; Humans; Norway; Paroxetine; Pregnancy; Pregnancy Trimester, Third; Selective Serotonin Reuptake Inhibitors; Venlafaxine Hydrochloride | 2017 |
The easy misuse of antidepressants during pregnancy is depressing.
Topics: Antidepressive Agents; Cohort Studies; Female; Humans; Paroxetine; Pregnancy | 2018 |
Perinatal exposure to the SSRI paroxetine alters the methylome landscape of the developing dentate gyrus.
Topics: Animals; Animals, Newborn; Antidepressive Agents; Behavior, Animal; Dentate Gyrus; Depression; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; Female; Gene Expression; Male; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Selective Serotonin Reuptake Inhibitors; Sex Factors | 2019 |
Dispensing patterns of selective serotonin reuptake inhibitors before, during and after pregnancy: a 16-year population-based cohort study from the Netherlands.
Topics: Adult; Antidepressive Agents; Cohort Studies; Drug Prescriptions; Female; Humans; Netherlands; Paroxetine; Peripartum Period; Population; Postpartum Period; Pregnancy; Pregnancy Complications; Selective Serotonin Reuptake Inhibitors | 2020 |
Effect of Pregnancy on Paroxetine-Induced Adiposity and Glucose Intolerance in Mice.
Topics: Adiposity; Animals; Aromatase; Estradiol; Female; Glucose Intolerance; Hormone Replacement Therapy; Mice; Mice, Inbred C57BL; Obesity; Ovary; Paroxetine; Pregnancy; Pregnancy Complications; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins | 2019 |
Characterization of transplacental transfer of paroxetine in perfused human placenta: development of a pharmacokinetic model to evaluate tapered dosing.
Topics: Antidepressive Agents, Second-Generation; Antipyrine; Female; Fetus; Humans; Kinetics; Maternal-Fetal Exchange; Models, Biological; Paroxetine; Perfusion; Permeability; Placenta; Pregnancy | 2013 |
Treacher Collins syndrome with multiple congenital heart defects after paroxetine exposure: case report.
Topics: Abnormalities, Multiple; Adult; Fatal Outcome; Female; Heart Defects, Congenital; Humans; Infant, Newborn; Male; Mandibulofacial Dysostosis; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Selective Serotonin Reuptake Inhibitors | 2014 |
Dispensing of potentially teratogenic drugs before conception and during pregnancy: a population-based study.
Topics: Adult; Doxycycline; Drug Prescriptions; Female; Humans; Netherlands; Norethindrone; Paroxetine; Practice Patterns, Physicians'; Pregnancy; Simvastatin; Teratogens; Time Factors; Triptorelin Pamoate | 2015 |
Early-life exposure to the SSRI paroxetine exacerbates depression-like behavior in anxiety/depression-prone rats.
Topics: Amygdala; Animals; Animals, Newborn; Anxiety Disorders; Depressive Disorder; Disease Models, Animal; Exploratory Behavior; Female; Gene Expression Regulation, Developmental; Genetic Predisposition to Disease; Hippocampus; Male; Maternal Behavior; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors | 2015 |
Paroxetine use during pregnancy and the risk of cardiac defects.
Topics: Abnormalities, Drug-Induced; Antidepressive Agents, Second-Generation; Female; Heart Defects, Congenital; Humans; Paroxetine; Pregnancy; Pregnancy Complications; Risk; Selective Serotonin Reuptake Inhibitors | 2016 |
Short-Term Safety of Paroxetine and Sertraline in Breastfed Infants: A Retrospective Cohort Study from a University Hospital.
Topics: Breast Feeding; Depression, Postpartum; Female; Hospitals, University; Humans; Infant; Infant, Newborn; Milk, Human; Mothers; Paroxetine; Practice Guidelines as Topic; Pregnancy; Retrospective Studies; Risk Assessment; Selective Serotonin Reuptake Inhibitors; Sertraline | 2016 |
Paroxetine and fluoxetine in pregnancy: a prospective, multicentre, controlled, observational study.
Topics: Abnormalities, Drug-Induced; Abortion, Induced; Adult; Antidepressive Agents, Second-Generation; Birth Weight; Case-Control Studies; Confidence Intervals; Drug Administration Schedule; Female; Fluoxetine; Gestational Age; Heart Defects, Congenital; Humans; Infant, Newborn; Maternal Age; Odds Ratio; Paroxetine; Pregnancy; Pregnancy Trimester, First; Prospective Studies; Risk; Selective Serotonin Reuptake Inhibitors | 2008 |
Should paroxetine be used to treat depression during pregnancy?
Topics: Abnormalities, Drug-Induced; Antidepressive Agents, Second-Generation; Depressive Disorder; Drug-Related Side Effects and Adverse Reactions; Evidence-Based Medicine; Female; Heart Defects, Congenital; Humans; Infant, Newborn; Paroxetine; Pregnancy; Pregnancy Complications; Randomized Controlled Trials as Topic; Secondary Prevention; Substance Withdrawal Syndrome | 2008 |
Re: alcohol and pregnancy: the pivotal role of the obstetrician.
Topics: Alcohol Drinking; Alcohol-Induced Disorders; Antidepressive Agents, Second-Generation; Female; Fetal Alcohol Spectrum Disorders; Humans; Obstetrics; Paroxetine; Physician's Role; Pregnancy; Prenatal Exposure Delayed Effects; Risk Assessment | 2008 |
Effect of exposure to selective serotonin reuptake inhibitors in utero on fetal growth: potential role for the IGF-I and HPA axes.
Topics: Adult; Birth Weight; Case-Control Studies; Citalopram; Female; Fetal Blood; Fetal Development; Fetal Growth Retardation; Fetus; Fluoxetine; Hormones; Humans; Hypothalamo-Hypophyseal System; Infant, Newborn; Insulin-Like Growth Factor I; Male; Paroxetine; Pituitary-Adrenal System; Placenta; Pregnancy; Selective Serotonin Reuptake Inhibitors | 2009 |
An imperfect literature and evidence-based medicine.
Topics: Abnormalities, Drug-Induced; Aged, 80 and over; Antidepressive Agents, Second-Generation; Depression, Postpartum; Evidence-Based Medicine; Female; Humans; Nortriptyline; Paroxetine; Pregnancy; Pregnancy Trimester, First; Randomized Controlled Trials as Topic; Review Literature as Topic; Selective Serotonin Reuptake Inhibitors; Sertraline; Sexual Behavior | 2009 |
Are selective serotonin reuptake inhibitors cardiac teratogens? Echocardiographic screening of newborns with persistent heart murmur.
Topics: Case-Control Studies; Echocardiography; Female; Fluoxetine; Heart Murmurs; Humans; Infant, Newborn; Maternal Exposure; Paroxetine; Pregnancy; Prevalence; Prospective Studies; Selective Serotonin Reuptake Inhibitors; Teratogens | 2009 |
Influence of the media on women taking antidepressants during pregnancy.
Topics: Adult; Adverse Drug Reaction Reporting Systems; Antidepressive Agents; Cardiovascular Abnormalities; Depressive Disorder; Drug Industry; Drug Information Services; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Internet; Mass Media; Paroxetine; Physician-Patient Relations; Pregnancy; Pregnancy Complications; Prevalence | 2009 |
GlaxoSmithKline told to pay family $2.5m after jury finds paroxetine caused son's heart defects.
Topics: Antidepressive Agents, Second-Generation; Child, Preschool; Compensation and Redress; Depressive Disorder; Drug Industry; Female; Heart Defects, Congenital; Humans; Male; Paroxetine; Philadelphia; Pregnancy; Pregnancy Complications | 2009 |
First-trimester use of paroxetine and congenital heart defects: a population-based case-control study.
Topics: Adult; Alcohol Drinking; Antidepressive Agents, Second-Generation; Case-Control Studies; Child; Female; Heart Septal Defects, Atrial; Humans; Infant, Newborn; Maternal Age; Netherlands; Paroxetine; Pregnancy; Pregnancy Trimester, First; Prenatal Exposure Delayed Effects; Selective Serotonin Reuptake Inhibitors; Smoking; Vital Statistics; Young Adult | 2010 |
Paroxetine exposure during pregnancy and the risk of cardiac malformations: what is the evidence?
Topics: Abnormalities, Drug-Induced; Adult; Data Interpretation, Statistical; Evidence-Based Medicine; Female; Heart Defects, Congenital; Humans; Meta-Analysis as Topic; Paroxetine; Pregnancy; Pregnancy Trimester, First; Selective Serotonin Reuptake Inhibitors; Uncertainty | 2010 |
Paroxetine exposure during pregnancy and cardiac malformations.
Topics: Abnormalities, Drug-Induced; Animals; Data Interpretation, Statistical; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Heart Defects, Congenital; Humans; Meta-Analysis as Topic; Mice; Odds Ratio; Paroxetine; Pregnancy; Pregnancy Trimester, First; Rabbits; Rats; Selective Serotonin Reuptake Inhibitors; Species Specificity; Uncertainty | 2010 |
S41744, a dual neurokinin (NK)1 receptor antagonist and serotonin (5-HT) reuptake inhibitor with potential antidepressant properties: a comparison to aprepitant (MK869) and paroxetine.
Topics: Animals; Antidepressive Agents; Aprepitant; Behavior, Animal; Brain; Extracellular Signal-Regulated MAP Kinases; Female; Gerbillinae; Guinea Pigs; Humans; Indans; Male; Mice; Morpholines; Motor Activity; Neurokinin-1 Receptor Antagonists; Pain Measurement; Paroxetine; Piperazines; Pregnancy; Radioligand Assay; Rats; Rats, Wistar; Receptors, Neurokinin-1; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Stress, Physiological | 2010 |
Use of antidepressants during pregnancy and the risk of spontaneous abortion.
Topics: Abortion, Spontaneous; Adolescent; Adult; Antidepressive Agents; Antidepressive Agents, Tricyclic; Case-Control Studies; Confidence Intervals; Cyclohexanols; Depressive Disorder; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Gestational Age; Humans; Middle Aged; Odds Ratio; Paroxetine; Pregnancy; Pregnancy Complications; Quebec; Registries; Risk Factors; Selective Serotonin Reuptake Inhibitors; Venlafaxine Hydrochloride; Young Adult | 2010 |
First trimester exposure to paroxetine and prevalence of cardiac defects: Meta-analysis of the literature: Unfortunately incomplete.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Female; Heart Defects, Congenital; Humans; Meta-Analysis as Topic; Paroxetine; Pregnancy; Pregnancy Trimester, First; Selective Serotonin Reuptake Inhibitors | 2010 |
Paroxetine use in pregnancy and increased risk of heart defects: Evaluating the evidence.
Topics: Abnormalities, Drug-Induced; Adult; Depression; Evidence-Based Medicine; Female; Heart Defects, Congenital; Humans; Meta-Analysis as Topic; Paroxetine; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Selective Serotonin Reuptake Inhibitors; Uncertainty | 2010 |
The effect of ascertainment bias in evaluating gestational antidepressant exposure.
Topics: Abnormalities, Drug-Induced; Antidepressive Agents, Second-Generation; Female; Heart Septal Defects, Ventricular; Humans; Paroxetine; Pregnancy | 2011 |
Antidepressant use during pregnancy. FPIN’s clinical inquiries.
Topics: Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Citalopram; Cyclohexanols; Evidence-Based Medicine; Female; Fluoxetine; Humans; Odds Ratio; Paroxetine; Physicians, Family; Pregnancy; Pregnancy Complications; Risk Assessment; Selective Serotonin Reuptake Inhibitors; Sertraline; Venlafaxine Hydrochloride | 2011 |
Selective serotonin reuptake inhibitors and risk for major congenital anomalies.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Alcohol Drinking; Female; Finland; Fluoxetine; Heart Septal Defects, Ventricular; Humans; Middle Aged; Paroxetine; Pregnancy; Risk Assessment; Selective Serotonin Reuptake Inhibitors; United States; Young Adult | 2011 |
[Influence of fluoxetine and paroxetine on anxiety-like behavior in young and adult prenatally stressed male rats].
Topics: Age Factors; Animals; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Anxiety; Behavior, Animal; Female; Fluoxetine; Male; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Sex Factors; Stress, Psychological | 2011 |
Selective serotonin reuptake inhibitors and risk for major congenital anomalies.
Topics: Abnormalities, Drug-Induced; Female; Fluoxetine; Humans; Paroxetine; Pregnancy; Selective Serotonin Reuptake Inhibitors | 2011 |
Selective serotonin reuptake inhibitors and risk for major congenital anomalies.
Topics: Abnormalities, Drug-Induced; Female; Fluoxetine; Humans; Paroxetine; Pregnancy; Selective Serotonin Reuptake Inhibitors | 2011 |
Selective serotonin reuptake inhibitors and risk for major congenital anomalies.
Topics: Abnormalities, Drug-Induced; Female; Fluoxetine; Humans; Paroxetine; Pregnancy; Selective Serotonin Reuptake Inhibitors | 2012 |
Antidepressant use during pregnancy and the risk of pregnancy-induced hypertension.
Topics: Adult; Antidepressive Agents; Case-Control Studies; Female; Humans; Hypertension, Pregnancy-Induced; Logistic Models; Multivariate Analysis; Odds Ratio; Paroxetine; Pregnancy; Pregnancy Complications; Prospective Studies; Quebec; Registries; Risk Assessment; Risk Factors; Selective Serotonin Reuptake Inhibitors; Young Adult | 2012 |
Paroxetine and neonatal withdrawal syndrome.
Topics: Adult; Antidepressive Agents, Second-Generation; Depression; Female; Humans; Infant, Newborn; Male; Neonatal Abstinence Syndrome; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects | 2010 |
Paroxetine use during pregnancy and perinatal outcomes including types of cardiac malformations in Quebec and France: a short communication.
Topics: Abnormalities, Drug-Induced; Antidepressive Agents, Second-Generation; Female; France; Heart Defects, Congenital; Humans; Infant, Newborn; Paroxetine; Pregnancy; Prevalence; Quebec | 2012 |
Onset of abnormal movements and cardiovascular symptoms after acute change in complex polypharmacy in a child with attention-deficit/hyperactivity disorder and mood symptoms.
Topics: Adrenergic alpha-Agonists; Antimanic Agents; Antipsychotic Agents; Aripiprazole; Asthma; Attention Deficit Disorder with Hyperactivity; Cardiovascular Diseases; Chest Pain; Child; Dyskinesia, Drug-Induced; Family; Female; Guanfacine; Humans; Lithium Chloride; Male; Mood Disorders; Neuropsychological Tests; Obesity; Paroxetine; Piperazines; Polypharmacy; Pregnancy; Prenatal Exposure Delayed Effects; Psychomotor Agitation; Quinolones; Selective Serotonin Reuptake Inhibitors; Smoking; Social Environment | 2012 |
A physiologically based pharmacokinetic model to predict disposition of CYP2D6 and CYP1A2 metabolized drugs in pregnant women.
Topics: Clonidine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Dextromethorphan; Female; Humans; Models, Biological; Paroxetine; Pregnancy; Theophylline | 2013 |
Perinatal outcome following third trimester exposure to paroxetine.
Topics: Adult; Case-Control Studies; Female; Humans; Hypoglycemia; Infant, Newborn; Jaundice; Maternal-Fetal Exchange; Neonatal Abstinence Syndrome; Paroxetine; Pregnancy; Pregnancy Trimester, Third; Prospective Studies; Respiratory Distress Syndrome, Newborn; Selective Serotonin Reuptake Inhibitors | 2002 |
Functional consequences of perinatal exposure to 3,4-methylenedioxymethamphetamine in rat brain.
Topics: Adrenergic Uptake Inhibitors; Animals; Animals, Newborn; Binding, Competitive; Brain; Female; Glucose; Male; N-Methyl-3,4-methylenedioxyamphetamine; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Serotonin; Time Factors; Tritium | 2002 |
Antidepressant induced cholestasis: hepatocellular redistribution of multidrug resistant protein (MRP2).
Topics: Acute Disease; Adult; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Biopsy; Cholestasis; Citalopram; Dothiepin; Female; Humans; Immunohistochemistry; Liver; Male; Middle Aged; Mitochondrial Proteins; Paroxetine; Pregnancy; Pregnancy Complications; Ribosomal Proteins; Saccharomyces cerevisiae Proteins | 2003 |
Omega-3 fatty acids for depression in pregnancy.
Topics: Adult; Depressive Disorder; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids, Omega-3; Female; Humans; Paroxetine; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Selective Serotonin Reuptake Inhibitors; Treatment Outcome | 2003 |
Placental passage of antidepressant medications.
Topics: Adult; Antidepressive Agents; Citalopram; Depressive Disorder; Dose-Response Relationship, Drug; Female; Fetal Blood; Fluoxetine; Humans; Maternal-Fetal Exchange; Paroxetine; Placenta; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Sertraline | 2003 |
Perinatal outcome following third-trimester exposure to paroxetine: an alternative interpretation.
Topics: Female; Humans; Infant, Newborn; Paroxetine; Pregnancy; Pregnancy Outcome; Pregnancy Trimester, Third; Prospective Studies; Respiratory Distress Syndrome, Newborn; Selective Serotonin Reuptake Inhibitors | 2003 |
Paroxetine withdrawal in a neonate with historical and laboratory confirmation.
Topics: Adult; Antidepressive Agents, Second-Generation; Female; Humans; Hydroxyindoleacetic Acid; Infant, Newborn; Male; Neonatal Abstinence Syndrome; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects | 2003 |
Neonatal intraventricular haemorrhage associated with maternal use of paroxetine.
Topics: Cerebral Hemorrhage; Contraindications; Female; Humans; Infant, Newborn; Male; Paroxetine; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Selective Serotonin Reuptake Inhibitors | 2003 |
Serotonin and its transporter on proliferation of fetal heart cells.
Topics: Analysis of Variance; Animals; Bromodeoxyuridine; Carrier Proteins; Cell Count; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Female; Fetal Heart; Immunohistochemistry; Male; Membrane Glycoproteins; Membrane Transport Proteins; Myocytes, Cardiac; Myosin Heavy Chains; Nerve Tissue Proteins; Paroxetine; Pregnancy; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins | 2003 |
Prenatal cocaine exposure potentiates paroxetine-induced desensitization of 5-HT2A receptor function in adult male rat offspring.
Topics: Adrenocorticotropic Hormone; Animals; Cocaine; Corticosterone; Drug Synergism; Female; Male; Oxytocin; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Protein Binding; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Serotonin 5-HT2 Receptor Antagonists | 2004 |
Paroxetine use throughout pregnancy: does it pose any risk to the neonate?
Topics: Abnormalities, Drug-Induced; Adult; Electroencephalography; Female; Humans; Hyperalgesia; Infant, Newborn; Male; Maternal Age; Maternal Exposure; Paroxetine; Pregnancy; Pregnancy, High-Risk; Selective Serotonin Reuptake Inhibitors | 2004 |
Selective serotonin reuptake inhibitor disrupts organization of thalamocortical somatosensory barrels during development.
Topics: Age Factors; Animals; Animals, Newborn; Body Weight; Carrier Proteins; Female; Immunohistochemistry; Isoenzymes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neural Pathways; Paroxetine; Phospholipase C beta; Pregnancy; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Somatosensory Cortex; Thalamus; Type C Phospholipases; Vibrissae | 2004 |
Neonatal complications after intrauterine exposure to SSRI antidepressants.
Topics: Antidepressive Agents; Citalopram; Depression; Female; Fluoxetine; Fluvoxamine; Follow-Up Studies; France; Humans; Infant, Newborn; Neonatal Abstinence Syndrome; Paroxetine; Pregnancy; Pregnancy Complications; Pregnancy Trimester, Third; Risk; Selective Serotonin Reuptake Inhibitors; Sertraline | 2004 |
Breastfeeding during maternal antidepressant treatment with serotonin reuptake inhibitors: infant exposure, clinical symptoms, and cytochrome p450 genotypes.
Topics: Adult; Aryl Hydrocarbon Hydroxylases; Breast Feeding; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Depression, Postpartum; Female; Genotype; Humans; Infant; Infant, Newborn; Lactation; Male; Maternal Exposure; Milk, Human; Mixed Function Oxygenases; Paroxetine; Pharmacogenetics; Phenotype; Pregnancy; Selective Serotonin Reuptake Inhibitors; Sertraline; Triglycerides | 2004 |
Severe adverse effects in a newborn with two defective CYP2D6 alleles after exposure to paroxetine during late pregnancy.
Topics: Alleles; Cytochrome P-450 CYP2D6; Female; Humans; Infant, Newborn; Nervous System Diseases; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects | 2004 |
Paroxetine is effective in desensitizing 5-HT1A receptor function in adult offspring exposed prenatally to cocaine.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; Animals; Cocaine; Corticosterone; Female; Fetus; Growth; Oxytocin; Paroxetine; Piperazines; Pregnancy; Prolactin; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Renin; Weight Gain | 2005 |
Neonatal symptoms following maternal paroxetine treatment: serotonin toxicity or paroxetine discontinuation syndrome?
Topics: Adult; Antidepressive Agents, Second-Generation; Depressive Disorder; Diagnosis, Differential; Female; Humans; Infant, Newborn; Neonatal Abstinence Syndrome; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome | 2005 |
Defective alleles may not have contributed to adverse effects.
Topics: Alleles; Cytochrome P-450 CYP2D6; Female; Fetus; Genotype; Humans; Paroxetine; Pregnancy; Selective Serotonin Reuptake Inhibitors | 2005 |
Neonatal signs following exposure to SSRIs.
Topics: Adult; Behavior; Female; Humans; Infant, Newborn; Neonatal Abstinence Syndrome; Paroxetine; Pregnancy; Receptors, sigma; Selective Serotonin Reuptake Inhibitors; Sigma-1 Receptor | 2005 |
Paroxetine (Paxil) and congenital malformations.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Databases, Factual; Female; Humans; Incidence; Middle Aged; Paroxetine; Pregnancy; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; United States | 2005 |
Antidepressant drugs during pregnancy and infant congenital heart defect.
Topics: Abnormalities, Drug-Induced; Antidepressive Agents; Clomipramine; Female; Heart Defects, Congenital; Humans; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Sweden | 2006 |
Paroxetine toxicity in a newborn after in utero exposure: clinical symptoms correlate with serum levels.
Topics: Adult; Breast Feeding; Drug Monitoring; Female; Humans; Infant, Newborn; Maternal-Fetal Exchange; Neonatal Abstinence Syndrome; Paroxetine; Pregnancy; Selective Serotonin Reuptake Inhibitors | 2006 |
Defective alleles may not have contributed to adverse effects.
Topics: Female; Humans; Infant, Newborn; Maternal-Fetal Exchange; Paroxetine; Pregnancy; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome | 2006 |
Defective alleles may not have contributed to adverse effects.
Topics: Cytochrome P-450 CYP2D6; Female; Humans; Infant, Newborn; Maternal-Fetal Exchange; Neonatal Abstinence Syndrome; Paroxetine; Pregnancy; Selective Serotonin Reuptake Inhibitors | 2006 |
Reexamining paroxetine and cognitive-behavioral therapy in postpartum depression and anxiety.
Topics: Anxiety Disorders; Bias; Cognitive Behavioral Therapy; Combined Modality Therapy; Comorbidity; Depression, Postpartum; Female; Humans; Paroxetine; Patient Selection; Pregnancy; Puerperal Disorders; Randomized Controlled Trials as Topic; Research Design; Selective Serotonin Reuptake Inhibitors; Treatment Outcome | 2005 |
Abrupt discontinuation of psychotropic drugs following confirmation of pregnancy: a risky practice.
Topics: Adult; Antidepressive Agents, Second-Generation; Counseling; Depression, Postpartum; Female; Humans; Mental Disorders; Paroxetine; Pregnancy; Pregnancy Complications; Psychotropic Drugs; Risk Factors; Substance Withdrawal Syndrome; Teratogens | 2005 |
Paroxetine may increase risk for congenital malformations.
Topics: Abnormalities, Drug-Induced; Antidepressive Agents, Second-Generation; Female; Heart Defects, Congenital; Humans; Paroxetine; Pregnancy; Pregnancy Trimester, First; Teratogens | 2006 |
Selective serotonin-reuptake inhibitors and persistent pulmonary hypertension of the newborn.
Topics: Abnormalities, Drug-Induced; Confounding Factors, Epidemiologic; Female; Heart Defects, Congenital; Humans; Infant, Newborn; Mental Disorders; Paroxetine; Persistent Fetal Circulation Syndrome; Pregnancy; Pregnancy Complications; Selective Serotonin Reuptake Inhibitors | 2006 |
Counseling pregnant women treated with paroxetine. Concern about cardiac malformations.
Topics: Canada; Depressive Disorder; Female; Heart Defects, Congenital; Humans; Paroxetine; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications; Risk; Selective Serotonin Reuptake Inhibitors | 2006 |
Prevalence and patterns of antidepressant drug use during pregnancy.
Topics: Adolescent; Adult; Age Factors; Antidepressive Agents; Benzodiazepines; Databases, Factual; Depressive Disorder; Drug Prescriptions; Drug Therapy, Combination; Drug Utilization Review; Female; Fluoxetine; Humans; Insurance, Pharmaceutical Services; Netherlands; Paroxetine; Pregnancy; Pregnancy Complications; Pregnancy Trimesters; Prevalence; Time Factors | 2006 |
Comment: paroxetine use during pregnancy: is it safe?
Topics: Depressive Disorder; Female; Humans; Paroxetine; Pregnancy; Pregnancy Complications | 2006 |
SSRI antidepressants and birth defects.
Topics: Abnormalities, Drug-Induced; Antidepressive Agents, Second-Generation; Clinical Trials as Topic; Cohort Studies; Cost-Benefit Analysis; Denmark; Depression; Female; Heart Defects, Congenital; Humans; Infant, Newborn; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Selective Serotonin Reuptake Inhibitors; Sweden; Teratogens; United States | 2006 |
First trimester exposure to paroxetine and risk of cardiac malformations in infants: the importance of dosage.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Antidepressive Agents, Second-Generation; Dose-Response Relationship, Drug; Female; Heart Defects, Congenital; Humans; Middle Aged; Paroxetine; Pregnancy; Pregnancy Trimester, First; Selective Serotonin Reuptake Inhibitors | 2007 |
Neonatal convulsions secondary to paroxetine withdrawal.
Topics: Antidepressive Agents, Second-Generation; Depression; Diagnosis, Differential; Epilepsy, Benign Neonatal; Female; Humans; Infant, Newborn; Male; Maternal Exposure; Neonatal Abstinence Syndrome; Paroxetine; Pregnancy; Pregnancy Complications | 2007 |
Are psychotropics drugs used in pregnancy?
Topics: Adolescent; Adult; Antidepressive Agents; Benzodiazepines; Cesarean Section; Depressive Disorder; Drug Utilization Review; Feeding and Eating Disorders; Female; Humans; Infant, Newborn; Lithium Compounds; Middle Aged; Obsessive-Compulsive Disorder; Paroxetine; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prospective Studies; Psychotropic Drugs; Spain; Surveys and Questionnaires; Treatment Outcome; Withholding Treatment | 2007 |
Prenatal maternal paroxetine treatment and neonatal mortality in the rat: a preliminary study.
Topics: Animals; Animals, Newborn; Female; Male; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred F344; Selective Serotonin Reuptake Inhibitors; Stress, Psychological | 2008 |
Paroxetine in the first trimester and the prevalence of congenital malformations.
Topics: Abnormalities, Drug-Induced; Adult; Cardiovascular Abnormalities; Cohort Studies; Female; Humans; Infant, Newborn; Male; Odds Ratio; Paroxetine; Pregnancy; Pregnancy Trimester, First; Prevalence; Selective Serotonin Reuptake Inhibitors | 2007 |
Increase in use of selective serotonin reuptake inhibitors in pregnancy during the last decade, a population-based cohort study from the Netherlands.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Depressive Disorder; Female; Fetal Development; Humans; Male; Middle Aged; Netherlands; Paroxetine; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Pregnancy Trimesters; Risk Assessment; Selective Serotonin Reuptake Inhibitors | 2008 |
Antidepressants in the postpartum period: additional considerations.
Topics: Antidepressive Agents; Breast Feeding; Depression, Postpartum; Female; Humans; Infant, Newborn; Paroxetine; Pregnancy; Pregnancy Complications; Psychotherapy; Risk Assessment; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome; Substance Withdrawal Syndrome | 2008 |
Evaluation of the risk of congenital cardiovascular defects associated with use of paroxetine during pregnancy.
Topics: Abnormalities, Drug-Induced; Antidepressive Agents, Second-Generation; Depressive Disorder, Major; Female; Heart Defects, Congenital; Humans; Infant; Infant, Newborn; Odds Ratio; Paroxetine; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Risk Assessment | 2008 |
Distribution of indoleamines and [3H]paroxetine binding in rat brain regions following acute or perinatal delta 9-tetrahydrocannabinol treatments.
Topics: Animals; Brain; Dronabinol; Female; Gyrus Cinguli; Hippocampus; Hydroxyindoleacetic Acid; Hypothalamus, Anterior; Locus Coeruleus; Male; Neostriatum; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Raphe Nuclei; Rats; Rats, Wistar; Serotonin; Substantia Nigra; Tritium | 1993 |
Alterations in local cerebral blood flow in mature rats following prenatal exposure to cocaine.
Topics: Animals; Autoradiography; Brain; Brain Chemistry; Cerebrovascular Circulation; Cocaine; Female; Glucose; Male; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley | 1994 |
Human placenta as a target organ for cocaine action: interaction of cocaine with the placental serotonin transporter.
Topics: Carrier Proteins; Cells, Cultured; Choriocarcinoma; Cocaine; Female; Humans; Iodine Radioisotopes; Membrane Glycoproteins; Membrane Transport Proteins; Microvilli; Nerve Tissue Proteins; Organ Specificity; Paroxetine; Placenta; Pregnancy; Serotonin; Serotonin Plasma Membrane Transport Proteins; Uterine Neoplasms | 1994 |
In utero methamphetamine effects: I. Behavior and monoamine uptake sites in adult offspring.
Topics: Animals; Behavior, Animal; Biogenic Monoamines; Brain; Female; Male; Mazindol; Methamphetamine; Paroxetine; Piperazines; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley | 1993 |
Programming of brainstem serotonin transporter development by prenatal glucocorticoids.
Topics: Animals; Binding Sites; Body Weight; Brain Stem; Carrier Proteins; Cell Differentiation; Cell Division; Dexamethasone; Female; Glucocorticoids; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neurons; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Tritium | 1996 |
Paroxetine withdrawal syndrome in a neonate.
Topics: Adult; Antidepressive Agents, Second-Generation; Female; Humans; Infant, Newborn; Male; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Substance Withdrawal Syndrome | 1997 |
Prenatal dexamethasone exposure alters brain monoamine metabolism and adrenocortical response in rat offspring.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenal Cortex; Aging; Analysis of Variance; Animals; Biogenic Monoamines; Brain; Corticosterone; Defecation; Dexamethasone; Dopamine; Female; Gestational Age; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Motor Activity; Organ Specificity; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Serotonin | 1997 |
Pregnancy outcome following maternal use of the new selective serotonin reuptake inhibitors: a prospective controlled multicenter study.
Topics: 1-Naphthylamine; Abnormalities, Drug-Induced; Adult; Antidepressive Agents; Cohort Studies; Female; Fluvoxamine; Humans; Infant, Newborn; Paroxetine; Pregnancy; Pregnancy Outcome; Pregnancy Trimester, First; Prospective Studies; Selective Serotonin Reuptake Inhibitors; Sertraline | 1998 |
Risk of fetal anomalies with exposure to selective serotonin reuptake inhibitors.
Topics: 1-Naphthylamine; Antidepressive Agents; Female; Fluvoxamine; Humans; Paroxetine; Pregnancy; Pregnancy Outcome; Risk; Selective Serotonin Reuptake Inhibitors; Sertraline | 1998 |
Effects of prenatal cocaine exposure on serotonin and norepinephrine transporter density in the rat brain.
Topics: Aging; Animals; Brain; Carrier Proteins; Cocaine; Female; Fluoxetine; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Organ Specificity; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Reference Values; Serotonin; Serotonin Plasma Membrane Transport Proteins; Symporters | 1998 |
Relationship between [125I]RTI-55-labeled cocaine binding sites and the serotonin transporter in rat placenta.
Topics: Animals; Autoradiography; Binding Sites; Carrier Proteins; Cocaine; Female; Immunohistochemistry; Iodine Radioisotopes; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Paroxetine; Placenta; Pregnancy; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Plasma Membrane Transport Proteins; Tissue Distribution | 1998 |
Molecular cloning, expression and characterization of a bovine serotonin transporter.
Topics: Amino Acid Sequence; Animals; Carrier Proteins; Cattle; Citalopram; Cloning, Molecular; Desipramine; Female; Fluoxetine; HeLa Cells; Humans; Imipramine; Kinetics; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Sequence Data; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Tissue Proteins; Organ Specificity; Paroxetine; Phylogeny; Pregnancy; Rats; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Sequence Alignment; Sequence Homology, Amino Acid; Serotonin; Serotonin Plasma Membrane Transport Proteins; Transfection | 1999 |
Safety of antidepressant use in pregnant and nursing women.
Topics: Antidepressive Agents; Breast Feeding; Depression, Postpartum; Depressive Disorder; Female; Humans; Infant, Newborn; Lactation; Paroxetine; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Risk; Selective Serotonin Reuptake Inhibitors; Sleep | 1999 |
Behavioral changes in developing mice after prenatal exposure to paroxetine (Paxil)
Topics: Aggression; Animals; Animals, Newborn; Anxiety; Behavior, Animal; Body Weight; Depression; Exploratory Behavior; Female; Homing Behavior; Litter Size; Male; Maternal Exposure; Mice; Motor Activity; Paroxetine; Play and Playthings; Pregnancy; Prenatal Exposure Delayed Effects; Random Allocation; Selective Serotonin Reuptake Inhibitors; Sleep; Time Factors; Vocalization, Animal | 1999 |
Paroxetine in human breast milk and nursing infants.
Topics: Breast Feeding; Chromatography, High Pressure Liquid; Depressive Disorder; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Infant, Newborn; Milk, Human; Paroxetine; Pregnancy; Puerperal Disorders | 2000 |
Dose of selective serotonin uptake inhibitors across pregnancy: clinical implications.
Topics: Depressive Disorder, Major; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluoxetine; Humans; Infant, Newborn; Paroxetine; Pregnancy; Pregnancy Complications; Selective Serotonin Reuptake Inhibitors; Sertraline; Treatment Outcome | 2000 |
The distribution of serotonergic nerves in microencephalic rats treated prenatally with methylazoxymethanol.
Topics: Animals; Autoradiography; Binding Sites; Brain; Carrier Proteins; Cerebellum; Cerebral Cortex; Female; Hippocampus; Membrane Glycoproteins; Membrane Transport Proteins; Methylazoxymethanol Acetate; Microcephaly; Nerve Tissue Proteins; Neurons; Nucleus Accumbens; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Raphe Nuclei; Rats; Rats, Wistar; RNA, Messenger; Serotonin; Serotonin Plasma Membrane Transport Proteins; Thalamus | 2000 |
Neurobiology of behavioral changes after prenatal exposure to paroxetine (Paxil)
Topics: Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Female; Mice; Nervous System; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects | 2000 |
Nicotine exposure during pregnancy is a factor which influences serotonin transporter density in the rat brain.
Topics: Animals; Brain Chemistry; Carrier Proteins; Female; Infusion Pumps; Injections, Subcutaneous; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Nicotine; Nicotinic Agonists; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins | 2001 |
Withdrawal reactions of a premature neonate after maternal use of paroxetine.
Topics: Antidepressive Agents, Second-Generation; Female; Humans; Infant, Newborn; Infant, Premature; Neonatal Abstinence Syndrome; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Remission, Spontaneous | 2001 |
Discontinuing antidepressants and benzodiazepines upon becoming pregnant. Beware of the risks of abrupt discontinuation.
Topics: Anti-Anxiety Agents; Antidepressive Agents; Evidence-Based Medicine; Female; Humans; Informed Consent; Lorazepam; Paroxetine; Patient Education as Topic; Preconception Care; Pregnancy; Risk Factors; Safety; Substance Withdrawal Syndrome | 2001 |
Serotonin reuptake inhibitor antidepressants and pregnancy: many unanswered questions.
Topics: Abnormalities, Drug-Induced; Antidepressive Agents, Second-Generation; Child; Child, Preschool; Clinical Trials as Topic; Depressive Disorder; Female; Fluoxetine; Fluvoxamine; Humans; Infant; Infant, Newborn; Paroxetine; Pregnancy; Selective Serotonin Reuptake Inhibitors; Sertraline; Treatment Outcome | 1999 |
Alterations in serotonin transporter expression in brain regions of rats exposed neonatally to chlorpyrifos.
Topics: Animals; Animals, Newborn; Brain Chemistry; Carrier Proteins; Chlorpyrifos; Cholinesterase Inhibitors; Female; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Paroxetine; Pregnancy; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Tritium | 2001 |
Fetal and adolescent nicotine administration: effects on CNS serotonergic systems.
Topics: Aging; Animals; Binding Sites; Brain; Carrier Proteins; Embryo, Mammalian; Female; Hydroxyindoleacetic Acid; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Degeneration; Nerve Tissue Proteins; Nicotine; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Presynaptic Terminals; Radioligand Assay; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Plasma Membrane Transport Proteins; Sex Characteristics; Synaptic Transmission; Tobacco Use Disorder | 2001 |
5-HT3 receptor-active drugs alter development of spinal serotonergic innervation: lack of effect of other serotonergic agents.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Animals; Biguanides; Female; Fenfluramine; Hypoglycemic Agents; Maternal-Fetal Exchange; Neurons; Pain; Paroxetine; Piperazines; Piperidines; Pregnancy; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spinal Cord; Tetrahydronaphthalenes; Tropanes | 1992 |
Prenatal cocaine exposure disrupts the development of the serotonergic system.
Topics: Animals; Animals, Newborn; Cocaine; Embryonic and Fetal Development; Female; Immunohistochemistry; Maternal-Fetal Exchange; Nerve Fibers; Neurons; Paroxetine; Piperidines; Pregnancy; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists | 1992 |
High-affinity paroxetine binding to the human placental serotonin transporter.
Topics: 4-Chloro-7-nitrobenzofurazan; Binding, Competitive; Biological Transport; Carrier Proteins; Female; Humans; Imidazoles; Kinetics; Microvilli; Paroxetine; Piperidines; Placenta; Pregnancy; Serotonin; Serotonin Antagonists; Sodium; Tetranitromethane; Tyrosine | 1990 |
Interaction of fluoxetine with the human placental serotonin transporter.
Topics: Carrier Proteins; Female; Fluoxetine; Humans; In Vitro Techniques; Microvilli; Paroxetine; Piperidines; Placenta; Pregnancy; Serotonin; Serotonin Antagonists | 1990 |
Prenatal treatment with a selective D1 receptor agonist (SKF 38393) alters adult [3H]paroxetine binding and dopamine and serotonin behavioral sensitivity.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Behavior, Animal; Brain Stem; Cerebral Cortex; Conditioning, Operant; Dopamine; Female; Kinetics; Paroxetine; Piperidines; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Serotonin | 1990 |
The reproductive toxicology of paroxetine.
Topics: Abnormalities, Drug-Induced; Animals; Antidepressive Agents; Body Weight; Dose-Response Relationship, Drug; Female; Litter Size; Paroxetine; Piperidines; Pregnancy; Pregnancy, Animal; Rabbits; Rats; Serotonin Antagonists | 1989 |