Page last updated: 2024-08-23

paroxetine and Pregnancy

paroxetine has been researched along with Pregnancy in 140 studies

Research

Studies (140)

TimeframeStudies, this research(%)All Research%
pre-19901 (0.71)18.7374
1990's20 (14.29)18.2507
2000's66 (47.14)29.6817
2010's44 (31.43)24.3611
2020's9 (6.43)2.80

Authors

AuthorsStudies
Alexandre, C; Alexandre, J; Desaunay, P; Dreyfus, M; Eude, LG; Fedrizzi, S; Guénolé, F; Uguz, F1
Breur, JMPJ; Leerssen, ECM; Tak, RO1
Doucet, N; Hudon Thibeault, AA; López de Los Santos, Y; Sanderson, JT; Vaillancourt, C1
Aucott, L; Fitton, CA; Fleming, M; Mackay, DF; McLay, JS; Pell, JP; Steiner, MFC1
Baryshnikova, E; Bellissima, V; Gabriella Tina, L; Gavilanes, D; Gazzolo, D; Godos, J; Nigro, F; Pluchinotta, F; Varrica, A; Ververs, T; Visser, GHA1
Akazawa, M; Ishikawa, T; Kikuchi, S; Kobayashi, N; Kuriyama, S; Mano, N; Miyakoda, K; Nishigori, H; Obara, T; Tomita, H; Yaegashi, N1
Cabrera, RM; Kim, J; Law, E; Linda Lin, Y; Wlodarczyk, BJ1
Esposito, DB; Petersen, JM; Werler, MM1
Reimers, A; Reis, M; Svensson, M1
Almurjan, A; Badhan, RKS; Macfarlane, H1
Brekke, M; Molden, E; Skogvoll, E; Spigset, O; Westin, AA1
Agius, M; Ripullone, K; Womersley, K1
Bewley, S; Braillon, A1
Bassi, M; Cauli, G; Gala, C; Iapichino, E; Marconi, AM; Quartieri Bollani, M; Rucci, P1
Clinton, SM; Glover, ME; Jackson, NL; McCoy, CR; Shupe, EA; Unroe, KA1
Bonsel, GJ; Lambregtse-van den Berg, MP; Molenaar, NM1
Hebert, MF; Hu, T; Wang, J; Zha, W1
Fujii, T; Hori, S; Matsuoka, S; Nagai, M; Ohtani, H; Satoh, H; Sawada, Y; Taketani, Y1
Blackwell, KA; Forray, A; Glover, J; Yonkers, KA1
Aydin, B; Beken, S; Dilli, D; Dinlen, N; Okumuş, N; Zenciroğlu, A1
Herings, RM; Houweling, LM; Ruiter, R; Straus, SM; Stricker, BH; Zomerdijk, IM1
Akil, H; Clinton, SM; Cohen, JL; Fant, AD; Glover, ME; Jackson, NL; Pugh, PC1
Bérard, A; Boukhris, T; Chaabane, S; Iessa, N; Muanda, FT; Zhao, JP1
Bérard, A; Boukhris, T; Chaabane, S; Muanda, FT; Zhao, J1
Arpaci, N; Uguz, F1
Avgil, M; Clementi, M; Di Gianantonio, E; Diav-Citrin, O; Ornoy, A; Schaefer, C; Shechtman, S; Wajnberg, R; Weber-Schoendorfer, C; Weinbaum, D1
Einarson, A; Einarson, TR; Koren, G; O'Brien, L; Sarkar, M1
Jureidini, J; Mintzes, B1
Ham, BJ; Han, C; Marks, DM; Masand, PS; Pae, CU; Park, MH; Patkar, AA1
Kennedy, D1
Bellantuono, C; Gentile, S1
Davidson, S; Gil-Ad, I; Harell, D; Maayan, R; Prokonov, D; Taler, M; Weizman, A1
Freeman, MP1
Lanza di Scalea, T; Wisner, KL1
Berant, M; Birk, E; Klinger, G; Linder, N; Merlob, P; Sirota, L; Stahl, B1
Ephross, SA; Olshan, AF; Poole, C; Wurst, KE1
Belitser, SV; Egberts, TC; Schobben, AF; Ververs, FF; Visser, GH; Voorbij, HA; Zwarts, P1
Einarson, A4
Tanne, JH1
Bakker, MK; Buys, CH; de Jong-van den Berg, LT; de Walle, HE; Kerstjens-Frederikse, WS1
Bérard, A1
Scialli, AR1
Ellfolk, M; Malm, H1
Brocco, M; Cremers, TI; de Jong, TR; de Nanteuil, G; Dekeyne, A; Di Cara, B; Flik, G; Gobert, A; Lejeune, F; Mannoury la Cour, C; Millan, MJ; Olivier, B; Rivet, JM1
Favrelière, S; Jaafari, N; Nourrisson, A; Pérault Pochat, MC1
Bérard, A; Broy, P; Nakhai-Pour, HR1
Einarson, A; Koren, G3
Antonioli, L; Blandizzi, C; Colucci, R; Corona, T; Fornai, M; Mantarro, S; Montagnani, S; Pergola, A; Ruggiero, E; Scollo, C; Testi, A; Tuccori, M1
Aitchison, KJ; Keers, R1
Aoun, J; Gorsane, MA; Krebs, MO; Soufia, M1
Koren, G1
Beste, J; Blackwell, JC; Patel, BN1
Artama, M; Gissler, M; Malm, H; Ritvanen, A1
Akulova, VK; Fedotova, YO; Ordian, NÉ; Pivina, SG1
Bozzo, P; Koren, G; Pupco, A1
Gilbert, AL; Grzeskowiak, LE; Morrison, JL1
Einarson, A; Puryear, LJ; Spinelli, M1
Evans, S; Gilbert, R; Nazareth, I; Petersen, I1
Bérard, A; De Vera, MA1
Dilillo, D; Penagini, F; Pogliani, L; Schneider, L; Zuccotti, GV1
Bérard, A; Crespin, S; Damase-Michel, C; Sheehy, O1
Coffey, DB; John, N; Potter, PO1
Byatt, N; Deligiannidis, KM; Freeman, MP1
Isoherranen, N; Ke, AB; Nallani, SC; Rostami-Hodjegan, A; Unadkat, JD; Zhao, P1
Costei, AM; Ho, T; Ito, S; Koren, G; Kozer, E1
Kelly, PA; McBean, DE; Olverman, HJ; Quate, L; Ritchie, IM1
Chilton, AP; Elias, E; Hubscher, SG; Milkiewicz, P1
Chiu, CC; Huang, SY; Shen, WW; Su, KP1
Altshuler, LL; Haynes, D; Hendrick, V; Hwang, S; Lee, E; Stowe, ZN1
Pham, B; Pryse-Phillips, W; Yuen, DE1
Coombs, RC; Isbister, GK; Jaiswal, S1
Newport, DJ; Stowe, ZN1
Dahlem, P; Duijvestijn, YC; Kalmeijer, MD; Passier, AL; Smiers, F1
Sari, Y; Zhou, FC1
Battaglia, G; Carrasco, GA; Chen, Z; Landry, M; Van de Kar, LD; Waimey, K1
Batash, D; Bulkowstein, M; Heyman, E; Keidar, R; Morag, I1
Sari, Y; Xu, Y; Zhou, FC1
Aamo, TO; Berle, JØ; Breilid, H; Spigset, O; Steen, VM; Zahlsen, K1
Bertilsson, L; Kytölä, J; Laine, K1
Battaglia, G; Carrasco, GA; Chen, Z; Muma, NA; Shankaran, M; Sripathirathan, K; Tetzlaff, J; Van De Kar, LD1
Clarke, P; Haddad, PM; Pal, BR; Sridhiran, S; Wieck, A1
Stiskal, JA2
Hashimoto, K1
Williams, M; Wooltorton, E1
Källén, B; Otterblad Olausson, P1
Knoppert, DC; Nimkar, R; Principi, T; Yuen, D1
McClendon, J1
Cuzzell, JZ1
Hallberg, P; Odlind, V; Sjöblom, V1
de Jong-van den Berg, L; Egberts, T; Kaasenbrood, H; Schobben, F; Ververs, T; Visser, G1
Thormahlen, GM1
Einarson, A; Wood, W1
Bérard, A; Blais, L; Oraichi, D; Ramos, E; Rey, E; St-André, M1
Ahmed, M; Parameshwaran, A; Swamy, P1
de la Rosa M, A; De Las Cuevas, C; Sanz, EJ; Troyano, JM1
Entsuah, R; Mangano, R; Pollack, M; Simon, NM; Tzanis, E; Zhang, Y1
Blanco, CE; Desbonnet, L; Leonard, BE; Myint, AM; Prickaerts, J; Scheepens, A; Steinbusch, HW; Van den Hove, DL1
Bar-Oz, B; Bérard, A; Boskovic, R; Einarson, A; Einarson, T; Koren, G; Malm, H; O'Brien, L1
Cole, JA; Cosmatos, IS; Ephross, SA; Walker, AM1
Bakker, MK; de Jong van den Berg, LT; de Walle, HE; Kölling, P; van den Berg, PB1
Burbeck, R; McDonald, L; Pilling, S; Tomson, D1
DeSantis, M; Einarson, A; Einarson, TR; Kennedy, D; Koren, G; Malm, H; Panchaud, A; Paulus, WD; Pistelli, A1
González, MI; Leret, ML; Molina-Holgado, E; Molina-Holgado, F; Reader, TA1
Kelly, PA; McBean, DE; Ritchie, IM; Sharkey, J1
Ganapathy, V; Leibach, FH; Mahesh, VB; Prasad, PD1
Caldecott-Hazard, S; Weissman, AD1
Barnes, GA; McCook, EC; Seidler, FJ; Slotkin, TA1
Ahlner, J; Dahl, ML; Olhager, E1
Kamei, K; Kitera, K; Mikuni, M; Muneoka, K; Ogawa, T; Takahashi, K; Takigawa, M1
Brochu, J; Cook, L; Feldkamp, M; Koren, G; Kulin, NA; Matsui, D; Ormond, K; Pastuszak, A; Rieder, M; Sage, SR; Schick-Boschetto, B; Spivey, G; Stein-Schechman, AK1
Grush, LR1
McReynolds, AM; Meyer, JS1
McReynolds, AM; Meyer, JS; Shearman, LP; Zhou, FC1
Kristensen, AS; Mortensen, OV; Rudnick, G; Wiborg, O1
Lamberg, L1
Christensen, HD; Coleman, FH; Gonzalez, CL; Rayburn, WF1
Cohen, LS; Hostetter, A; Nemeroff, CB; Owens, MJ; Ritchie, JC; Stowe, ZN1
Hostetter, A; Llewellyn, A; McLaughlin, E; Stowe, ZN; Strader, JR1
Hagino, Y; Kodama, Y; Nonaka, R; Watanabe, M1
Friedman, EH1
Kamei, K; Kato, H; Mimura, Y; Muneoka, K; Ogawa, T; Takigawa, M1
Bosschaart, AN; Kok-Van Rooij, GW; Nijhuis, IJ1
Einarson, A; Koren, G; Selby, P1
Raines, KW; Seidler, FJ; Slotkin, TA1
Ali, SF; Seidler, FJ; Slikker, W; Slotkin, TA; Xu, Z1
Bell, J; Whitaker-Azmitia, PM; Zhang, XN1
Akbari, HM; Azmitia, EC; Kramer, HK; Spear, LP; Whitaker-Azmitia, PM1
Cool, DR; Ganapathy, V; Leibach, FH1
Cool, DR; Ganapathy, V; Liebach, FH1
Quartermain, D; Shemer, AV; Whitaker-Azmitia, PM1
Baldwin, JA; Davidson, EJ; Pritchard, AL; Ridings, JE1

Reviews

21 review(s) available for paroxetine and Pregnancy

ArticleYear
Benefits and Risks of Antidepressant Drugs During Pregnancy: A Systematic Review of Meta-analyses.
    Paediatric drugs, 2023, Volume: 25, Issue:3

    Topics: Antidepressive Agents; Child; Female; Fluoxetine; Humans; Infant, Newborn; Paroxetine; Pregnancy; Premature Birth; Risk Assessment; Sertraline

2023
In utero exposure to antidepressant medication and neonatal and child outcomes: a systematic review.
    Acta psychiatrica Scandinavica, 2020, Volume: 141, Issue:1

    Topics: Antidepressive Agents; Attention Deficit Disorder with Hyperactivity; Autism Spectrum Disorder; Child; Conduct Disorder; Congenital Abnormalities; Depressive Disorder; Female; Gestational Age; Heart Defects, Congenital; Humans; Infant, Newborn; Neurodevelopmental Disorders; Paroxetine; Pregnancy; Pregnancy Complications; Premature Birth; Prenatal Exposure Delayed Effects; Risk Factors

2020
What are the risks associated with different Selective Serotonin Re-uptake Inhibitors (SSRIs) to treat depression and anxiety in pregnancy? An evaluation of current evidence.
    Psychiatria Danubina, 2017, Volume: 29, Issue:Suppl 3

    Topics: Adult; Anxiety; Citalopram; Depression; Female; Humans; Paroxetine; Pregnancy; Pregnancy Complications; Selective Serotonin Reuptake Inhibitors; Serotonin

2017
Antidepressant use in pregnant and postpartum women.
    Annual review of clinical psychology, 2014, Volume: 10

    Topics: Antidepressive Agents; Depression, Postpartum; Depressive Disorder; Female; Heart Defects, Congenital; Humans; Infant, Newborn; Paroxetine; Persistent Fetal Circulation Syndrome; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects

2014
The risk of major cardiac malformations associated with paroxetine use during the first trimester of pregnancy: a systematic review and meta-analysis.
    British journal of clinical pharmacology, 2016, Volume: 81, Issue:4

    Topics: Abnormalities, Drug-Induced; Female; Heart Defects, Congenital; Humans; Maternal Exposure; Paroxetine; Pregnancy; Pregnancy Trimester, First; Risk Assessment; Selective Serotonin Reuptake Inhibitors

2016
Does paroxetine cause cardiac malformations?
    Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC, 2008, Volume: 30, Issue:8

    Topics: Case-Control Studies; Cohort Studies; Drug-Related Side Effects and Adverse Reactions; Female; Heart Defects, Congenital; Humans; Paroxetine; Pregnancy; Pregnancy Trimester, First; Selective Serotonin Reuptake Inhibitors

2008
Paroxetine: safety and tolerability issues.
    Expert opinion on drug safety, 2008, Volume: 7, Issue:6

    Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Child; Clinical Trials as Topic; Delayed-Action Preparations; Drug Interactions; Female; Humans; Mental Disorders; Paroxetine; Pregnancy; Selective Serotonin Reuptake Inhibitors

2008
Selective serotonin reuptake inhibitor exposure during early pregnancy and the risk of fetal major malformations: focus on paroxetine.
    The Journal of clinical psychiatry, 2009, Volume: 70, Issue:3

    Topics: Abnormalities, Drug-Induced; Antidepressive Agents, Second-Generation; Controlled Clinical Trials as Topic; Cross-Sectional Studies; Depressive Disorder; Female; Humans; Infant, Newborn; Paroxetine; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Prospective Studies; Risk; Selective Serotonin Reuptake Inhibitors

2009
Antidepressant medication use during breastfeeding.
    Clinical obstetrics and gynecology, 2009, Volume: 52, Issue:3

    Topics: Antidepressive Agents, Second-Generation; Breast Feeding; Citalopram; Depression, Postpartum; Female; Fluoxetine; Humans; Infant; Lactation; Paroxetine; Pregnancy; Selective Serotonin Reuptake Inhibitors; Sertraline

2009
First trimester paroxetine use and the prevalence of congenital, specifically cardiac, defects: a meta-analysis of epidemiological studies.
    Birth defects research. Part A, Clinical and molecular teratology, 2010, Volume: 88, Issue:3

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Female; Heart Defects, Congenital; Humans; Odds Ratio; Paroxetine; Pregnancy; Pregnancy Trimester, First; Selective Serotonin Reuptake Inhibitors

2010
Risks associated with in utero and lactation exposure to selective serotonin reuptake inhibitors (SSRIs).
    Reproductive toxicology (Elmsford, N.Y.), 2010, Volume: 30, Issue:2

    Topics: Adult; Breast Feeding; Cardiovascular Abnormalities; Congenital Abnormalities; Female; Fluoxetine; Humans; Hypertension, Pulmonary; Infant, Newborn; Lactation; Maternal Exposure; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; PubMed; Respiratory Distress Syndrome, Newborn; Risk Assessment; Selective Serotonin Reuptake Inhibitors

2010
[Treatment of depressed pregnant women by selective serotonin reuptake inhibitors: risk for the foetus and the newborn].
    L'Encephale, 2010, Volume: 36 Suppl 2

    Topics: Abnormalities, Drug-Induced; Antidepressive Agents, Second-Generation; Depressive Disorder; Female; Gestational Age; Humans; Infant, Newborn; Paroxetine; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Risk; Secondary Prevention; Selective Serotonin Reuptake Inhibitors

2010
Use of selective serotonin reuptake inhibitors during pregnancy and risk of major and cardiovascular malformations: an update.
    Postgraduate medicine, 2010, Volume: 122, Issue:4

    Topics: Abnormalities, Drug-Induced; Cardiovascular Abnormalities; Citalopram; Depression; Female; Fluoxetine; Fluvoxamine; Humans; Maternal-Fetal Exchange; Paroxetine; Pregnancy; Pregnancy Complications; Selective Serotonin Reuptake Inhibitors; Sertraline; Teratogens

2010
Gender differences in antidepressant drug response.
    International review of psychiatry (Abingdon, England), 2010, Volume: 22, Issue:5

    Topics: Abnormalities, Drug-Induced; Antidepressive Agents; Antidepressive Agents, Tricyclic; Depression, Postpartum; Depressive Disorder; Drug Tolerance; Female; Humans; Male; Milk, Human; Paroxetine; Pregnancy; Prevalence; Risk Factors; Selective Serotonin Reuptake Inhibitors; Sex Factors; Treatment Outcome; Women

2010
[SSRIs and pregnancy: a review of the literature].
    L'Encephale, 2010, Volume: 36, Issue:6

    Topics: Abnormalities, Drug-Induced; Antidepressive Agents; Depressive Disorder, Major; Drug-Related Side Effects and Adverse Reactions; Female; Heart Defects, Congenital; Humans; Infant, Newborn; Infant, Newborn, Diseases; Paroxetine; Pregnancy; Pregnancy Complications; Pregnancy Trimester, Third; Risk Assessment; Selective Serotonin Reuptake Inhibitors

2010
Investigating outcomes following the use of selective serotonin reuptake inhibitors for treating depression in pregnancy: a focus on methodological issues.
    Drug safety, 2011, Nov-01, Volume: 34, Issue:11

    Topics: Depressive Disorder; Female; Humans; Paroxetine; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Selective Serotonin Reuptake Inhibitors; Treatment Outcome

2011
Publishing statistically significant results with questionable clinical importance: focus on antidepressant use in pregnancy.
    The Journal of clinical psychiatry, 2012, Volume: 73, Issue:11

    Topics: Abnormalities, Drug-Induced; Antidepressive Agents; Bias; Causality; Compensation and Redress; Cross-Sectional Studies; Data Interpretation, Statistical; Depressive Disorder; Drug Utilization; Female; Heart Defects, Congenital; Humans; Infant, Newborn; Paroxetine; Preconception Care; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Product Surveillance, Postmarketing; Publishing; Risk Factors; Selective Serotonin Reuptake Inhibitors

2012
Antidepressant use in pregnancy: a critical review focused on risks and controversies.
    Acta psychiatrica Scandinavica, 2013, Volume: 127, Issue:2

    Topics: Abnormalities, Drug-Induced; Antidepressive Agents; Depressive Disorder; Female; Humans; Infant, Newborn; Paroxetine; Persistent Fetal Circulation Syndrome; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Prenatal Exposure Delayed Effects; Risk Factors; Selective Serotonin Reuptake Inhibitors

2013
Clinical management of perinatal depression: focus on paroxetine.
    Psychopharmacology bulletin, 2003,Spring, Volume: 37 Suppl 1

    Topics: Adult; Antidepressive Agents, Second-Generation; Depression, Postpartum; Female; Fetus; Humans; Infant, Newborn; Paroxetine; Pregnancy; Pregnancy Complications; Selective Serotonin Reuptake Inhibitors

2003
Paroxetine use during pregnancy: is it safe?
    The Annals of pharmacotherapy, 2006, Volume: 40, Issue:10

    Topics: Female; Humans; Infant, Newborn; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Risk Factors

2006
Paroxetine and congenital malformations: meta-Analysis and consideration of potential confounding factors.
    Clinical therapeutics, 2007, Volume: 29, Issue:5

    Topics: Abnormalities, Drug-Induced; Adult; Amniocentesis; Antidepressive Agents, Second-Generation; Anxiety; Depression; Electrocardiography; Female; Humans; Infant, Newborn; Paroxetine; Pregnancy; Pregnancy Complications; Pregnancy Trimesters; Ultrasonography

2007

Trials

3 trial(s) available for paroxetine and Pregnancy

ArticleYear
Promoting the well-being of mothers with multidisciplinary psychosocial interventions in the perinatal period.
    Journal of affective disorders, 2019, 03-01, Volume: 246

    Topics: Adult; Antidepressive Agents; Anxiety; Combined Modality Therapy; Depression; Depression, Postpartum; Female; Humans; Longitudinal Studies; Mothers; Paroxetine; Patient Acceptance of Health Care; Perinatal Care; Pregnancy; Pregnancy Complications; Psychotherapy; Risk Factors; Sertraline; Treatment Outcome

2019
Effect of cytochrome P450 2D6 genotype on maternal paroxetine plasma concentrations during pregnancy.
    Clinical pharmacokinetics, 2009, Volume: 48, Issue:10

    Topics: Adult; Antidepressive Agents, Second-Generation; Cohort Studies; Cytochrome P-450 CYP2D6; Depression; Drug Monitoring; Female; Genotype; Humans; Middle Aged; Paroxetine; Pharmacogenetics; Pregnancy; Surveys and Questionnaires; Treatment Outcome; Young Adult

2009
A randomized controlled trial of venlafaxine ER and paroxetine in the treatment of outpatients with panic disorder.
    Psychopharmacology, 2007, Volume: 194, Issue:2

    Topics: Abortion, Spontaneous; Administration, Oral; Adult; Affective Disorders, Psychotic; Cyclohexanols; Delayed-Action Preparations; Diagnostic and Statistical Manual of Mental Disorders; Diarrhea; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Outpatients; Panic Disorder; Paroxetine; Pregnancy; Pregnancy, Unplanned; Remission Induction; Selective Serotonin Reuptake Inhibitors; Time Factors; Treatment Outcome; Venlafaxine Hydrochloride

2007

Other Studies

116 other study(ies) available for paroxetine and Pregnancy

ArticleYear
Severe transient neonatal long QT syndrome due to maternal paroxetine usage: a case report.
    Cardiology in the young, 2019, Volume: 29, Issue:10

    Topics: Electrocardiography; Female; Humans; Infant, Newborn; Long QT Syndrome; Maternal Exposure; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index

2019
Serotonin and serotonin reuptake inhibitors alter placental aromatase.
    The Journal of steroid biochemistry and molecular biology, 2019, Volume: 195

    Topics: Aromatase; Cells, Cultured; Citalopram; Female; Fluoxetine; Humans; Molecular Docking Simulation; Paroxetine; Placenta; Pregnancy; Selective Serotonin Reuptake Inhibitors; Serotonin; Sertraline; Trophoblasts; Venlafaxine Hydrochloride

2019
Antenatal maternal antidepressants drugs treatment affects S100B levels in maternal-fetal biological fluids in a dose dependent manner.
    Clinica chimica acta; international journal of clinical chemistry, 2020, Volume: 501

    Topics: Adult; Amniotic Fluid; Antidepressive Agents; Biomarkers; Central Nervous System Diseases; Clinical Laboratory Techniques; Cross-Sectional Studies; Dose-Response Relationship, Drug; Female; Humans; Maternal-Fetal Relations; Paroxetine; Pregnancy; S100 Calcium Binding Protein beta Subunit

2020
Antidepressant prescriptions for prenatal and postpartum women in Japan: A health administrative database study.
    Journal of affective disorders, 2020, 03-01, Volume: 264

    Topics: Antidepressive Agents; Female; Humans; Japan; Paroxetine; Postpartum Period; Pregnancy; Selective Serotonin Reuptake Inhibitors

2020
The teratogenic effects of sertraline in mice.
    Birth defects research, 2020, Volume: 112, Issue:13

    Topics: Animals; Citalopram; Female; Humans; Mice; Mice, Inbred ICR; Paroxetine; Pregnancy; Selective Serotonin Reuptake Inhibitors; Sertraline

2020
Selective serotonin reuptake inhibitor use patterns among commercially insured US pregnancies (2005-2014).
    Archives of women's mental health, 2021, Volume: 24, Issue:1

    Topics: Adolescent; Adult; Cohort Studies; Female; Humans; Middle Aged; Paroxetine; Pregnancy; Pregnancy Trimesters; Selective Serotonin Reuptake Inhibitors; Sertraline; Young Adult

2021
[Pharmacokinetics of antidepressants during pregnancy].
    Lakartidningen, 2020, 04-21, Volume: 117

    Topics: Antidepressive Agents; Cytochrome P-450 CYP2D6; Female; Fluoxetine; Humans; Paroxetine; Pregnancy; Pregnancy Complications; Selective Serotonin Reuptake Inhibitors

2020
Precision dosing-based optimisation of paroxetine during pregnancy for poor and ultrarapid CYP2D6 metabolisers: a virtual clinical trial pharmacokinetics study.
    The Journal of pharmacy and pharmacology, 2020, Volume: 72, Issue:8

    Topics: Adult; Computer Simulation; Cytochrome P-450 CYP2D6; Drug Dosage Calculations; Female; Humans; Middle Aged; Models, Biological; Paroxetine; Pharmacogenomic Variants; Phenotype; Pregnancy; Pregnancy Trimesters; Selective Serotonin Reuptake Inhibitors

2020
Selective serotonin reuptake inhibitors and venlafaxine in pregnancy: Changes in drug disposition.
    PloS one, 2017, Volume: 12, Issue:7

    Topics: Adult; Antidepressive Agents; Citalopram; Databases, Factual; Depressive Disorder; Drug Monitoring; Female; Fluvoxamine; Humans; Norway; Paroxetine; Pregnancy; Pregnancy Trimester, Third; Selective Serotonin Reuptake Inhibitors; Venlafaxine Hydrochloride

2017
The easy misuse of antidepressants during pregnancy is depressing.
    British journal of clinical pharmacology, 2018, Volume: 84, Issue:10

    Topics: Antidepressive Agents; Cohort Studies; Female; Humans; Paroxetine; Pregnancy

2018
Perinatal exposure to the SSRI paroxetine alters the methylome landscape of the developing dentate gyrus.
    The European journal of neuroscience, 2019, Volume: 50, Issue:2

    Topics: Animals; Animals, Newborn; Antidepressive Agents; Behavior, Animal; Dentate Gyrus; Depression; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; Female; Gene Expression; Male; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Selective Serotonin Reuptake Inhibitors; Sex Factors

2019
Dispensing patterns of selective serotonin reuptake inhibitors before, during and after pregnancy: a 16-year population-based cohort study from the Netherlands.
    Archives of women's mental health, 2020, Volume: 23, Issue:1

    Topics: Adult; Antidepressive Agents; Cohort Studies; Drug Prescriptions; Female; Humans; Netherlands; Paroxetine; Peripartum Period; Population; Postpartum Period; Pregnancy; Pregnancy Complications; Selective Serotonin Reuptake Inhibitors

2020
Effect of Pregnancy on Paroxetine-Induced Adiposity and Glucose Intolerance in Mice.
    The Journal of pharmacology and experimental therapeutics, 2019, Volume: 371, Issue:1

    Topics: Adiposity; Animals; Aromatase; Estradiol; Female; Glucose Intolerance; Hormone Replacement Therapy; Mice; Mice, Inbred C57BL; Obesity; Ovary; Paroxetine; Pregnancy; Pregnancy Complications; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins

2019
Characterization of transplacental transfer of paroxetine in perfused human placenta: development of a pharmacokinetic model to evaluate tapered dosing.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:12

    Topics: Antidepressive Agents, Second-Generation; Antipyrine; Female; Fetus; Humans; Kinetics; Maternal-Fetal Exchange; Models, Biological; Paroxetine; Perfusion; Permeability; Placenta; Pregnancy

2013
Treacher Collins syndrome with multiple congenital heart defects after paroxetine exposure: case report.
    Genetic counseling (Geneva, Switzerland), 2014, Volume: 25, Issue:1

    Topics: Abnormalities, Multiple; Adult; Fatal Outcome; Female; Heart Defects, Congenital; Humans; Infant, Newborn; Male; Mandibulofacial Dysostosis; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Selective Serotonin Reuptake Inhibitors

2014
Dispensing of potentially teratogenic drugs before conception and during pregnancy: a population-based study.
    BJOG : an international journal of obstetrics and gynaecology, 2015, Volume: 122, Issue:8

    Topics: Adult; Doxycycline; Drug Prescriptions; Female; Humans; Netherlands; Norethindrone; Paroxetine; Practice Patterns, Physicians'; Pregnancy; Simvastatin; Teratogens; Time Factors; Triptorelin Pamoate

2015
Early-life exposure to the SSRI paroxetine exacerbates depression-like behavior in anxiety/depression-prone rats.
    Neuroscience, 2015, Jan-22, Volume: 284

    Topics: Amygdala; Animals; Animals, Newborn; Anxiety Disorders; Depressive Disorder; Disease Models, Animal; Exploratory Behavior; Female; Gene Expression Regulation, Developmental; Genetic Predisposition to Disease; Hippocampus; Male; Maternal Behavior; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors

2015
Paroxetine use during pregnancy and the risk of cardiac defects.
    British journal of clinical pharmacology, 2016, Volume: 82, Issue:2

    Topics: Abnormalities, Drug-Induced; Antidepressive Agents, Second-Generation; Female; Heart Defects, Congenital; Humans; Paroxetine; Pregnancy; Pregnancy Complications; Risk; Selective Serotonin Reuptake Inhibitors

2016
Short-Term Safety of Paroxetine and Sertraline in Breastfed Infants: A Retrospective Cohort Study from a University Hospital.
    Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine, 2016, Volume: 11

    Topics: Breast Feeding; Depression, Postpartum; Female; Hospitals, University; Humans; Infant; Infant, Newborn; Milk, Human; Mothers; Paroxetine; Practice Guidelines as Topic; Pregnancy; Retrospective Studies; Risk Assessment; Selective Serotonin Reuptake Inhibitors; Sertraline

2016
Paroxetine and fluoxetine in pregnancy: a prospective, multicentre, controlled, observational study.
    British journal of clinical pharmacology, 2008, Volume: 66, Issue:5

    Topics: Abnormalities, Drug-Induced; Abortion, Induced; Adult; Antidepressive Agents, Second-Generation; Birth Weight; Case-Control Studies; Confidence Intervals; Drug Administration Schedule; Female; Fluoxetine; Gestational Age; Heart Defects, Congenital; Humans; Infant, Newborn; Maternal Age; Odds Ratio; Paroxetine; Pregnancy; Pregnancy Trimester, First; Prospective Studies; Risk; Selective Serotonin Reuptake Inhibitors

2008
Should paroxetine be used to treat depression during pregnancy?
    The American journal of psychiatry, 2008, Volume: 165, Issue:11

    Topics: Abnormalities, Drug-Induced; Antidepressive Agents, Second-Generation; Depressive Disorder; Drug-Related Side Effects and Adverse Reactions; Evidence-Based Medicine; Female; Heart Defects, Congenital; Humans; Infant, Newborn; Paroxetine; Pregnancy; Pregnancy Complications; Randomized Controlled Trials as Topic; Secondary Prevention; Substance Withdrawal Syndrome

2008
Re: alcohol and pregnancy: the pivotal role of the obstetrician.
    The Australian & New Zealand journal of obstetrics & gynaecology, 2008, Volume: 48, Issue:6

    Topics: Alcohol Drinking; Alcohol-Induced Disorders; Antidepressive Agents, Second-Generation; Female; Fetal Alcohol Spectrum Disorders; Humans; Obstetrics; Paroxetine; Physician's Role; Pregnancy; Prenatal Exposure Delayed Effects; Risk Assessment

2008
Effect of exposure to selective serotonin reuptake inhibitors in utero on fetal growth: potential role for the IGF-I and HPA axes.
    Pediatric research, 2009, Volume: 65, Issue:2

    Topics: Adult; Birth Weight; Case-Control Studies; Citalopram; Female; Fetal Blood; Fetal Development; Fetal Growth Retardation; Fetus; Fluoxetine; Hormones; Humans; Hypothalamo-Hypophyseal System; Infant, Newborn; Insulin-Like Growth Factor I; Male; Paroxetine; Pituitary-Adrenal System; Placenta; Pregnancy; Selective Serotonin Reuptake Inhibitors

2009
An imperfect literature and evidence-based medicine.
    The Journal of clinical psychiatry, 2009, Volume: 70, Issue:3

    Topics: Abnormalities, Drug-Induced; Aged, 80 and over; Antidepressive Agents, Second-Generation; Depression, Postpartum; Evidence-Based Medicine; Female; Humans; Nortriptyline; Paroxetine; Pregnancy; Pregnancy Trimester, First; Randomized Controlled Trials as Topic; Review Literature as Topic; Selective Serotonin Reuptake Inhibitors; Sertraline; Sexual Behavior

2009
Are selective serotonin reuptake inhibitors cardiac teratogens? Echocardiographic screening of newborns with persistent heart murmur.
    Birth defects research. Part A, Clinical and molecular teratology, 2009, Volume: 85, Issue:10

    Topics: Case-Control Studies; Echocardiography; Female; Fluoxetine; Heart Murmurs; Humans; Infant, Newborn; Maternal Exposure; Paroxetine; Pregnancy; Prevalence; Prospective Studies; Selective Serotonin Reuptake Inhibitors; Teratogens

2009
Influence of the media on women taking antidepressants during pregnancy.
    The Journal of clinical psychiatry, 2009, Volume: 70, Issue:9

    Topics: Adult; Adverse Drug Reaction Reporting Systems; Antidepressive Agents; Cardiovascular Abnormalities; Depressive Disorder; Drug Industry; Drug Information Services; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Internet; Mass Media; Paroxetine; Physician-Patient Relations; Pregnancy; Pregnancy Complications; Prevalence

2009
GlaxoSmithKline told to pay family $2.5m after jury finds paroxetine caused son's heart defects.
    BMJ (Clinical research ed.), 2009, Oct-15, Volume: 339

    Topics: Antidepressive Agents, Second-Generation; Child, Preschool; Compensation and Redress; Depressive Disorder; Drug Industry; Female; Heart Defects, Congenital; Humans; Male; Paroxetine; Philadelphia; Pregnancy; Pregnancy Complications

2009
First-trimester use of paroxetine and congenital heart defects: a population-based case-control study.
    Birth defects research. Part A, Clinical and molecular teratology, 2010, Volume: 88, Issue:2

    Topics: Adult; Alcohol Drinking; Antidepressive Agents, Second-Generation; Case-Control Studies; Child; Female; Heart Septal Defects, Atrial; Humans; Infant, Newborn; Maternal Age; Netherlands; Paroxetine; Pregnancy; Pregnancy Trimester, First; Prenatal Exposure Delayed Effects; Selective Serotonin Reuptake Inhibitors; Smoking; Vital Statistics; Young Adult

2010
Paroxetine exposure during pregnancy and the risk of cardiac malformations: what is the evidence?
    Birth defects research. Part A, Clinical and molecular teratology, 2010, Volume: 88, Issue:3

    Topics: Abnormalities, Drug-Induced; Adult; Data Interpretation, Statistical; Evidence-Based Medicine; Female; Heart Defects, Congenital; Humans; Meta-Analysis as Topic; Paroxetine; Pregnancy; Pregnancy Trimester, First; Selective Serotonin Reuptake Inhibitors; Uncertainty

2010
Paroxetine exposure during pregnancy and cardiac malformations.
    Birth defects research. Part A, Clinical and molecular teratology, 2010, Volume: 88, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Data Interpretation, Statistical; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Heart Defects, Congenital; Humans; Meta-Analysis as Topic; Mice; Odds Ratio; Paroxetine; Pregnancy; Pregnancy Trimester, First; Rabbits; Rats; Selective Serotonin Reuptake Inhibitors; Species Specificity; Uncertainty

2010
S41744, a dual neurokinin (NK)1 receptor antagonist and serotonin (5-HT) reuptake inhibitor with potential antidepressant properties: a comparison to aprepitant (MK869) and paroxetine.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2010, Volume: 20, Issue:9

    Topics: Animals; Antidepressive Agents; Aprepitant; Behavior, Animal; Brain; Extracellular Signal-Regulated MAP Kinases; Female; Gerbillinae; Guinea Pigs; Humans; Indans; Male; Mice; Morpholines; Motor Activity; Neurokinin-1 Receptor Antagonists; Pain Measurement; Paroxetine; Piperazines; Pregnancy; Radioligand Assay; Rats; Rats, Wistar; Receptors, Neurokinin-1; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Stress, Physiological

2010
Use of antidepressants during pregnancy and the risk of spontaneous abortion.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2010, Jul-13, Volume: 182, Issue:10

    Topics: Abortion, Spontaneous; Adolescent; Adult; Antidepressive Agents; Antidepressive Agents, Tricyclic; Case-Control Studies; Confidence Intervals; Cyclohexanols; Depressive Disorder; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Gestational Age; Humans; Middle Aged; Odds Ratio; Paroxetine; Pregnancy; Pregnancy Complications; Quebec; Registries; Risk Factors; Selective Serotonin Reuptake Inhibitors; Venlafaxine Hydrochloride; Young Adult

2010
First trimester exposure to paroxetine and prevalence of cardiac defects: Meta-analysis of the literature: Unfortunately incomplete.
    Birth defects research. Part A, Clinical and molecular teratology, 2010, Volume: 88, Issue:7

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Female; Heart Defects, Congenital; Humans; Meta-Analysis as Topic; Paroxetine; Pregnancy; Pregnancy Trimester, First; Selective Serotonin Reuptake Inhibitors

2010
Paroxetine use in pregnancy and increased risk of heart defects: Evaluating the evidence.
    Canadian family physician Medecin de famille canadien, 2010, Volume: 56, Issue:8

    Topics: Abnormalities, Drug-Induced; Adult; Depression; Evidence-Based Medicine; Female; Heart Defects, Congenital; Humans; Meta-Analysis as Topic; Paroxetine; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Selective Serotonin Reuptake Inhibitors; Uncertainty

2010
The effect of ascertainment bias in evaluating gestational antidepressant exposure.
    Journal of population therapeutics and clinical pharmacology = Journal de la therapeutique des populations et de la pharmacologie clinique, 2011, Volume: 18

    Topics: Abnormalities, Drug-Induced; Antidepressive Agents, Second-Generation; Female; Heart Septal Defects, Ventricular; Humans; Paroxetine; Pregnancy

2011
Antidepressant use during pregnancy. FPIN’s clinical inquiries.
    American family physician, 2011, May-15, Volume: 83, Issue:10

    Topics: Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Citalopram; Cyclohexanols; Evidence-Based Medicine; Female; Fluoxetine; Humans; Odds Ratio; Paroxetine; Physicians, Family; Pregnancy; Pregnancy Complications; Risk Assessment; Selective Serotonin Reuptake Inhibitors; Sertraline; Venlafaxine Hydrochloride

2011
Selective serotonin reuptake inhibitors and risk for major congenital anomalies.
    Obstetrics and gynecology, 2011, Volume: 118, Issue:1

    Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Alcohol Drinking; Female; Finland; Fluoxetine; Heart Septal Defects, Ventricular; Humans; Middle Aged; Paroxetine; Pregnancy; Risk Assessment; Selective Serotonin Reuptake Inhibitors; United States; Young Adult

2011
[Influence of fluoxetine and paroxetine on anxiety-like behavior in young and adult prenatally stressed male rats].
    Eksperimental'naia i klinicheskaia farmakologiia, 2011, Volume: 74, Issue:4

    Topics: Age Factors; Animals; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Anxiety; Behavior, Animal; Female; Fluoxetine; Male; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Sex Factors; Stress, Psychological

2011
Selective serotonin reuptake inhibitors and risk for major congenital anomalies.
    Obstetrics and gynecology, 2011, Volume: 118, Issue:4

    Topics: Abnormalities, Drug-Induced; Female; Fluoxetine; Humans; Paroxetine; Pregnancy; Selective Serotonin Reuptake Inhibitors

2011
Selective serotonin reuptake inhibitors and risk for major congenital anomalies.
    Obstetrics and gynecology, 2011, Volume: 118, Issue:6

    Topics: Abnormalities, Drug-Induced; Female; Fluoxetine; Humans; Paroxetine; Pregnancy; Selective Serotonin Reuptake Inhibitors

2011
Selective serotonin reuptake inhibitors and risk for major congenital anomalies.
    Obstetrics and gynecology, 2012, Volume: 119, Issue:1

    Topics: Abnormalities, Drug-Induced; Female; Fluoxetine; Humans; Paroxetine; Pregnancy; Selective Serotonin Reuptake Inhibitors

2012
Antidepressant use during pregnancy and the risk of pregnancy-induced hypertension.
    British journal of clinical pharmacology, 2012, Volume: 74, Issue:2

    Topics: Adult; Antidepressive Agents; Case-Control Studies; Female; Humans; Hypertension, Pregnancy-Induced; Logistic Models; Multivariate Analysis; Odds Ratio; Paroxetine; Pregnancy; Pregnancy Complications; Prospective Studies; Quebec; Registries; Risk Assessment; Risk Factors; Selective Serotonin Reuptake Inhibitors; Young Adult

2012
Paroxetine and neonatal withdrawal syndrome.
    BMJ case reports, 2010, Apr-29, Volume: 2010

    Topics: Adult; Antidepressive Agents, Second-Generation; Depression; Female; Humans; Infant, Newborn; Male; Neonatal Abstinence Syndrome; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects

2010
Paroxetine use during pregnancy and perinatal outcomes including types of cardiac malformations in Quebec and France: a short communication.
    Current drug safety, 2012, Volume: 7, Issue:3

    Topics: Abnormalities, Drug-Induced; Antidepressive Agents, Second-Generation; Female; France; Heart Defects, Congenital; Humans; Infant, Newborn; Paroxetine; Pregnancy; Prevalence; Quebec

2012
Onset of abnormal movements and cardiovascular symptoms after acute change in complex polypharmacy in a child with attention-deficit/hyperactivity disorder and mood symptoms.
    Journal of child and adolescent psychopharmacology, 2012, Volume: 22, Issue:5

    Topics: Adrenergic alpha-Agonists; Antimanic Agents; Antipsychotic Agents; Aripiprazole; Asthma; Attention Deficit Disorder with Hyperactivity; Cardiovascular Diseases; Chest Pain; Child; Dyskinesia, Drug-Induced; Family; Female; Guanfacine; Humans; Lithium Chloride; Male; Mood Disorders; Neuropsychological Tests; Obesity; Paroxetine; Piperazines; Polypharmacy; Pregnancy; Prenatal Exposure Delayed Effects; Psychomotor Agitation; Quinolones; Selective Serotonin Reuptake Inhibitors; Smoking; Social Environment

2012
A physiologically based pharmacokinetic model to predict disposition of CYP2D6 and CYP1A2 metabolized drugs in pregnant women.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:4

    Topics: Clonidine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Dextromethorphan; Female; Humans; Models, Biological; Paroxetine; Pregnancy; Theophylline

2013
Perinatal outcome following third trimester exposure to paroxetine.
    Archives of pediatrics & adolescent medicine, 2002, Volume: 156, Issue:11

    Topics: Adult; Case-Control Studies; Female; Humans; Hypoglycemia; Infant, Newborn; Jaundice; Maternal-Fetal Exchange; Neonatal Abstinence Syndrome; Paroxetine; Pregnancy; Pregnancy Trimester, Third; Prospective Studies; Respiratory Distress Syndrome, Newborn; Selective Serotonin Reuptake Inhibitors

2002
Functional consequences of perinatal exposure to 3,4-methylenedioxymethamphetamine in rat brain.
    British journal of pharmacology, 2002, Volume: 137, Issue:7

    Topics: Adrenergic Uptake Inhibitors; Animals; Animals, Newborn; Binding, Competitive; Brain; Female; Glucose; Male; N-Methyl-3,4-methylenedioxyamphetamine; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Serotonin; Time Factors; Tritium

2002
Antidepressant induced cholestasis: hepatocellular redistribution of multidrug resistant protein (MRP2).
    Gut, 2003, Volume: 52, Issue:2

    Topics: Acute Disease; Adult; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Biopsy; Cholestasis; Citalopram; Dothiepin; Female; Humans; Immunohistochemistry; Liver; Male; Middle Aged; Mitochondrial Proteins; Paroxetine; Pregnancy; Pregnancy Complications; Ribosomal Proteins; Saccharomyces cerevisiae Proteins

2003
Omega-3 fatty acids for depression in pregnancy.
    The American journal of psychiatry, 2003, Volume: 160, Issue:2

    Topics: Adult; Depressive Disorder; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids, Omega-3; Female; Humans; Paroxetine; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Selective Serotonin Reuptake Inhibitors; Treatment Outcome

2003
Placental passage of antidepressant medications.
    The American journal of psychiatry, 2003, Volume: 160, Issue:5

    Topics: Adult; Antidepressive Agents; Citalopram; Depressive Disorder; Dose-Response Relationship, Drug; Female; Fetal Blood; Fluoxetine; Humans; Maternal-Fetal Exchange; Paroxetine; Placenta; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Sertraline

2003
Perinatal outcome following third-trimester exposure to paroxetine: an alternative interpretation.
    Archives of pediatrics & adolescent medicine, 2003, Volume: 157, Issue:6

    Topics: Female; Humans; Infant, Newborn; Paroxetine; Pregnancy; Pregnancy Outcome; Pregnancy Trimester, Third; Prospective Studies; Respiratory Distress Syndrome, Newborn; Selective Serotonin Reuptake Inhibitors

2003
Paroxetine withdrawal in a neonate with historical and laboratory confirmation.
    European journal of pediatrics, 2003, Volume: 162, Issue:10

    Topics: Adult; Antidepressive Agents, Second-Generation; Female; Humans; Hydroxyindoleacetic Acid; Infant, Newborn; Male; Neonatal Abstinence Syndrome; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects

2003
Neonatal intraventricular haemorrhage associated with maternal use of paroxetine.
    British journal of clinical pharmacology, 2003, Volume: 56, Issue:5

    Topics: Cerebral Hemorrhage; Contraindications; Female; Humans; Infant, Newborn; Male; Paroxetine; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Selective Serotonin Reuptake Inhibitors

2003
Serotonin and its transporter on proliferation of fetal heart cells.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2003, Volume: 21, Issue:8

    Topics: Analysis of Variance; Animals; Bromodeoxyuridine; Carrier Proteins; Cell Count; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Female; Fetal Heart; Immunohistochemistry; Male; Membrane Glycoproteins; Membrane Transport Proteins; Myocytes, Cardiac; Myosin Heavy Chains; Nerve Tissue Proteins; Paroxetine; Pregnancy; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins

2003
Prenatal cocaine exposure potentiates paroxetine-induced desensitization of 5-HT2A receptor function in adult male rat offspring.
    Neuropharmacology, 2004, Volume: 46, Issue:7

    Topics: Adrenocorticotropic Hormone; Animals; Cocaine; Corticosterone; Drug Synergism; Female; Male; Oxytocin; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Protein Binding; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Serotonin 5-HT2 Receptor Antagonists

2004
Paroxetine use throughout pregnancy: does it pose any risk to the neonate?
    Journal of toxicology. Clinical toxicology, 2004, Volume: 42, Issue:1

    Topics: Abnormalities, Drug-Induced; Adult; Electroencephalography; Female; Humans; Hyperalgesia; Infant, Newborn; Male; Maternal Age; Maternal Exposure; Paroxetine; Pregnancy; Pregnancy, High-Risk; Selective Serotonin Reuptake Inhibitors

2004
Selective serotonin reuptake inhibitor disrupts organization of thalamocortical somatosensory barrels during development.
    Brain research. Developmental brain research, 2004, Jun-21, Volume: 150, Issue:2

    Topics: Age Factors; Animals; Animals, Newborn; Body Weight; Carrier Proteins; Female; Immunohistochemistry; Isoenzymes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neural Pathways; Paroxetine; Phospholipase C beta; Pregnancy; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Somatosensory Cortex; Thalamus; Type C Phospholipases; Vibrissae

2004
Neonatal complications after intrauterine exposure to SSRI antidepressants.
    Prescrire international, 2004, Volume: 13, Issue:71

    Topics: Antidepressive Agents; Citalopram; Depression; Female; Fluoxetine; Fluvoxamine; Follow-Up Studies; France; Humans; Infant, Newborn; Neonatal Abstinence Syndrome; Paroxetine; Pregnancy; Pregnancy Complications; Pregnancy Trimester, Third; Risk; Selective Serotonin Reuptake Inhibitors; Sertraline

2004
Breastfeeding during maternal antidepressant treatment with serotonin reuptake inhibitors: infant exposure, clinical symptoms, and cytochrome p450 genotypes.
    The Journal of clinical psychiatry, 2004, Volume: 65, Issue:9

    Topics: Adult; Aryl Hydrocarbon Hydroxylases; Breast Feeding; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Depression, Postpartum; Female; Genotype; Humans; Infant; Infant, Newborn; Lactation; Male; Maternal Exposure; Milk, Human; Mixed Function Oxygenases; Paroxetine; Pharmacogenetics; Phenotype; Pregnancy; Selective Serotonin Reuptake Inhibitors; Sertraline; Triglycerides

2004
Severe adverse effects in a newborn with two defective CYP2D6 alleles after exposure to paroxetine during late pregnancy.
    Therapeutic drug monitoring, 2004, Volume: 26, Issue:6

    Topics: Alleles; Cytochrome P-450 CYP2D6; Female; Humans; Infant, Newborn; Nervous System Diseases; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects

2004
Paroxetine is effective in desensitizing 5-HT1A receptor function in adult offspring exposed prenatally to cocaine.
    Psychopharmacology, 2005, Volume: 180, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; Animals; Cocaine; Corticosterone; Female; Fetus; Growth; Oxytocin; Paroxetine; Piperazines; Pregnancy; Prolactin; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Renin; Weight Gain

2005
Neonatal symptoms following maternal paroxetine treatment: serotonin toxicity or paroxetine discontinuation syndrome?
    Journal of psychopharmacology (Oxford, England), 2005, Volume: 19, Issue:5

    Topics: Adult; Antidepressive Agents, Second-Generation; Depressive Disorder; Diagnosis, Differential; Female; Humans; Infant, Newborn; Neonatal Abstinence Syndrome; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome

2005
Defective alleles may not have contributed to adverse effects.
    Therapeutic drug monitoring, 2005, Volume: 27, Issue:5

    Topics: Alleles; Cytochrome P-450 CYP2D6; Female; Fetus; Genotype; Humans; Paroxetine; Pregnancy; Selective Serotonin Reuptake Inhibitors

2005
Neonatal signs following exposure to SSRIs.
    Human psychopharmacology, 2005, Volume: 20, Issue:7

    Topics: Adult; Behavior; Female; Humans; Infant, Newborn; Neonatal Abstinence Syndrome; Paroxetine; Pregnancy; Receptors, sigma; Selective Serotonin Reuptake Inhibitors; Sigma-1 Receptor

2005
Paroxetine (Paxil) and congenital malformations.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2005, Nov-22, Volume: 173, Issue:11

    Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Databases, Factual; Female; Humans; Incidence; Middle Aged; Paroxetine; Pregnancy; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; United States

2005
Antidepressant drugs during pregnancy and infant congenital heart defect.
    Reproductive toxicology (Elmsford, N.Y.), 2006, Volume: 21, Issue:3

    Topics: Abnormalities, Drug-Induced; Antidepressive Agents; Clomipramine; Female; Heart Defects, Congenital; Humans; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Sweden

2006
Paroxetine toxicity in a newborn after in utero exposure: clinical symptoms correlate with serum levels.
    Therapeutic drug monitoring, 2006, Volume: 28, Issue:1

    Topics: Adult; Breast Feeding; Drug Monitoring; Female; Humans; Infant, Newborn; Maternal-Fetal Exchange; Neonatal Abstinence Syndrome; Paroxetine; Pregnancy; Selective Serotonin Reuptake Inhibitors

2006
Defective alleles may not have contributed to adverse effects.
    Therapeutic drug monitoring, 2006, Volume: 28, Issue:1

    Topics: Female; Humans; Infant, Newborn; Maternal-Fetal Exchange; Paroxetine; Pregnancy; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome

2006
Defective alleles may not have contributed to adverse effects.
    Therapeutic drug monitoring, 2006, Volume: 28, Issue:1

    Topics: Cytochrome P-450 CYP2D6; Female; Humans; Infant, Newborn; Maternal-Fetal Exchange; Neonatal Abstinence Syndrome; Paroxetine; Pregnancy; Selective Serotonin Reuptake Inhibitors

2006
Reexamining paroxetine and cognitive-behavioral therapy in postpartum depression and anxiety.
    The Journal of clinical psychiatry, 2005, Volume: 66, Issue:11

    Topics: Anxiety Disorders; Bias; Cognitive Behavioral Therapy; Combined Modality Therapy; Comorbidity; Depression, Postpartum; Female; Humans; Paroxetine; Patient Selection; Pregnancy; Puerperal Disorders; Randomized Controlled Trials as Topic; Research Design; Selective Serotonin Reuptake Inhibitors; Treatment Outcome

2005
Abrupt discontinuation of psychotropic drugs following confirmation of pregnancy: a risky practice.
    Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC, 2005, Volume: 27, Issue:11

    Topics: Adult; Antidepressive Agents, Second-Generation; Counseling; Depression, Postpartum; Female; Humans; Mental Disorders; Paroxetine; Pregnancy; Pregnancy Complications; Psychotropic Drugs; Risk Factors; Substance Withdrawal Syndrome; Teratogens

2005
Paroxetine may increase risk for congenital malformations.
    Dermatology nursing, 2006, Volume: 18, Issue:1

    Topics: Abnormalities, Drug-Induced; Antidepressive Agents, Second-Generation; Female; Heart Defects, Congenital; Humans; Paroxetine; Pregnancy; Pregnancy Trimester, First; Teratogens

2006
Selective serotonin-reuptake inhibitors and persistent pulmonary hypertension of the newborn.
    The New England journal of medicine, 2006, May-18, Volume: 354, Issue:20

    Topics: Abnormalities, Drug-Induced; Confounding Factors, Epidemiologic; Female; Heart Defects, Congenital; Humans; Infant, Newborn; Mental Disorders; Paroxetine; Persistent Fetal Circulation Syndrome; Pregnancy; Pregnancy Complications; Selective Serotonin Reuptake Inhibitors

2006
Counseling pregnant women treated with paroxetine. Concern about cardiac malformations.
    Canadian family physician Medecin de famille canadien, 2006, Volume: 52

    Topics: Canada; Depressive Disorder; Female; Heart Defects, Congenital; Humans; Paroxetine; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications; Risk; Selective Serotonin Reuptake Inhibitors

2006
Prevalence and patterns of antidepressant drug use during pregnancy.
    European journal of clinical pharmacology, 2006, Volume: 62, Issue:10

    Topics: Adolescent; Adult; Age Factors; Antidepressive Agents; Benzodiazepines; Databases, Factual; Depressive Disorder; Drug Prescriptions; Drug Therapy, Combination; Drug Utilization Review; Female; Fluoxetine; Humans; Insurance, Pharmaceutical Services; Netherlands; Paroxetine; Pregnancy; Pregnancy Complications; Pregnancy Trimesters; Prevalence; Time Factors

2006
Comment: paroxetine use during pregnancy: is it safe?
    The Annals of pharmacotherapy, 2006, Volume: 40, Issue:12

    Topics: Depressive Disorder; Female; Humans; Paroxetine; Pregnancy; Pregnancy Complications

2006
SSRI antidepressants and birth defects.
    Prescrire international, 2006, Volume: 15, Issue:86

    Topics: Abnormalities, Drug-Induced; Antidepressive Agents, Second-Generation; Clinical Trials as Topic; Cohort Studies; Cost-Benefit Analysis; Denmark; Depression; Female; Heart Defects, Congenital; Humans; Infant, Newborn; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Selective Serotonin Reuptake Inhibitors; Sweden; Teratogens; United States

2006
First trimester exposure to paroxetine and risk of cardiac malformations in infants: the importance of dosage.
    Birth defects research. Part B, Developmental and reproductive toxicology, 2007, Volume: 80, Issue:1

    Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Antidepressive Agents, Second-Generation; Dose-Response Relationship, Drug; Female; Heart Defects, Congenital; Humans; Middle Aged; Paroxetine; Pregnancy; Pregnancy Trimester, First; Selective Serotonin Reuptake Inhibitors

2007
Neonatal convulsions secondary to paroxetine withdrawal.
    JPMA. The Journal of the Pakistan Medical Association, 2007, Volume: 57, Issue:3

    Topics: Antidepressive Agents, Second-Generation; Depression; Diagnosis, Differential; Epilepsy, Benign Neonatal; Female; Humans; Infant, Newborn; Male; Maternal Exposure; Neonatal Abstinence Syndrome; Paroxetine; Pregnancy; Pregnancy Complications

2007
Are psychotropics drugs used in pregnancy?
    Pharmacoepidemiology and drug safety, 2007, Volume: 16, Issue:9

    Topics: Adolescent; Adult; Antidepressive Agents; Benzodiazepines; Cesarean Section; Depressive Disorder; Drug Utilization Review; Feeding and Eating Disorders; Female; Humans; Infant, Newborn; Lithium Compounds; Middle Aged; Obsessive-Compulsive Disorder; Paroxetine; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prospective Studies; Psychotropic Drugs; Spain; Surveys and Questionnaires; Treatment Outcome; Withholding Treatment

2007
Prenatal maternal paroxetine treatment and neonatal mortality in the rat: a preliminary study.
    Neonatology, 2008, Volume: 93, Issue:1

    Topics: Animals; Animals, Newborn; Female; Male; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred F344; Selective Serotonin Reuptake Inhibitors; Stress, Psychological

2008
Paroxetine in the first trimester and the prevalence of congenital malformations.
    Pharmacoepidemiology and drug safety, 2007, Volume: 16, Issue:10

    Topics: Abnormalities, Drug-Induced; Adult; Cardiovascular Abnormalities; Cohort Studies; Female; Humans; Infant, Newborn; Male; Odds Ratio; Paroxetine; Pregnancy; Pregnancy Trimester, First; Prevalence; Selective Serotonin Reuptake Inhibitors

2007
Increase in use of selective serotonin reuptake inhibitors in pregnancy during the last decade, a population-based cohort study from the Netherlands.
    British journal of clinical pharmacology, 2008, Volume: 65, Issue:4

    Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Depressive Disorder; Female; Fetal Development; Humans; Male; Middle Aged; Netherlands; Paroxetine; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Pregnancy Trimesters; Risk Assessment; Selective Serotonin Reuptake Inhibitors

2008
Antidepressants in the postpartum period: additional considerations.
    The American journal of psychiatry, 2008, Volume: 165, Issue:2

    Topics: Antidepressive Agents; Breast Feeding; Depression, Postpartum; Female; Humans; Infant, Newborn; Paroxetine; Pregnancy; Pregnancy Complications; Psychotherapy; Risk Assessment; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome; Substance Withdrawal Syndrome

2008
Evaluation of the risk of congenital cardiovascular defects associated with use of paroxetine during pregnancy.
    The American journal of psychiatry, 2008, Volume: 165, Issue:6

    Topics: Abnormalities, Drug-Induced; Antidepressive Agents, Second-Generation; Depressive Disorder, Major; Female; Heart Defects, Congenital; Humans; Infant; Infant, Newborn; Odds Ratio; Paroxetine; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Risk Assessment

2008
Distribution of indoleamines and [3H]paroxetine binding in rat brain regions following acute or perinatal delta 9-tetrahydrocannabinol treatments.
    Neurochemical research, 1993, Volume: 18, Issue:11

    Topics: Animals; Brain; Dronabinol; Female; Gyrus Cinguli; Hippocampus; Hydroxyindoleacetic Acid; Hypothalamus, Anterior; Locus Coeruleus; Male; Neostriatum; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Raphe Nuclei; Rats; Rats, Wistar; Serotonin; Substantia Nigra; Tritium

1993
Alterations in local cerebral blood flow in mature rats following prenatal exposure to cocaine.
    Neuroscience, 1994, Volume: 60, Issue:1

    Topics: Animals; Autoradiography; Brain; Brain Chemistry; Cerebrovascular Circulation; Cocaine; Female; Glucose; Male; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley

1994
Human placenta as a target organ for cocaine action: interaction of cocaine with the placental serotonin transporter.
    Placenta, 1994, Volume: 15, Issue:3

    Topics: Carrier Proteins; Cells, Cultured; Choriocarcinoma; Cocaine; Female; Humans; Iodine Radioisotopes; Membrane Glycoproteins; Membrane Transport Proteins; Microvilli; Nerve Tissue Proteins; Organ Specificity; Paroxetine; Placenta; Pregnancy; Serotonin; Serotonin Plasma Membrane Transport Proteins; Uterine Neoplasms

1994
In utero methamphetamine effects: I. Behavior and monoamine uptake sites in adult offspring.
    Synapse (New York, N.Y.), 1993, Volume: 13, Issue:3

    Topics: Animals; Behavior, Animal; Biogenic Monoamines; Brain; Female; Male; Mazindol; Methamphetamine; Paroxetine; Piperazines; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley

1993
Programming of brainstem serotonin transporter development by prenatal glucocorticoids.
    Brain research. Developmental brain research, 1996, May-31, Volume: 93, Issue:1-2

    Topics: Animals; Binding Sites; Body Weight; Brain Stem; Carrier Proteins; Cell Differentiation; Cell Division; Dexamethasone; Female; Glucocorticoids; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neurons; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Tritium

1996
Paroxetine withdrawal syndrome in a neonate.
    The British journal of psychiatry : the journal of mental science, 1997, Volume: 171

    Topics: Adult; Antidepressive Agents, Second-Generation; Female; Humans; Infant, Newborn; Male; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Substance Withdrawal Syndrome

1997
Prenatal dexamethasone exposure alters brain monoamine metabolism and adrenocortical response in rat offspring.
    The American journal of physiology, 1997, Volume: 273, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenal Cortex; Aging; Analysis of Variance; Animals; Biogenic Monoamines; Brain; Corticosterone; Defecation; Dexamethasone; Dopamine; Female; Gestational Age; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Motor Activity; Organ Specificity; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Serotonin

1997
Pregnancy outcome following maternal use of the new selective serotonin reuptake inhibitors: a prospective controlled multicenter study.
    JAMA, 1998, Feb-25, Volume: 279, Issue:8

    Topics: 1-Naphthylamine; Abnormalities, Drug-Induced; Adult; Antidepressive Agents; Cohort Studies; Female; Fluvoxamine; Humans; Infant, Newborn; Paroxetine; Pregnancy; Pregnancy Outcome; Pregnancy Trimester, First; Prospective Studies; Selective Serotonin Reuptake Inhibitors; Sertraline

1998
Risk of fetal anomalies with exposure to selective serotonin reuptake inhibitors.
    JAMA, 1998, Jun-17, Volume: 279, Issue:23

    Topics: 1-Naphthylamine; Antidepressive Agents; Female; Fluvoxamine; Humans; Paroxetine; Pregnancy; Pregnancy Outcome; Risk; Selective Serotonin Reuptake Inhibitors; Sertraline

1998
Effects of prenatal cocaine exposure on serotonin and norepinephrine transporter density in the rat brain.
    Annals of the New York Academy of Sciences, 1998, Jun-21, Volume: 846

    Topics: Aging; Animals; Brain; Carrier Proteins; Cocaine; Female; Fluoxetine; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Organ Specificity; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Reference Values; Serotonin; Serotonin Plasma Membrane Transport Proteins; Symporters

1998
Relationship between [125I]RTI-55-labeled cocaine binding sites and the serotonin transporter in rat placenta.
    The American journal of physiology, 1998, Volume: 275, Issue:6

    Topics: Animals; Autoradiography; Binding Sites; Carrier Proteins; Cocaine; Female; Immunohistochemistry; Iodine Radioisotopes; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Paroxetine; Placenta; Pregnancy; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Plasma Membrane Transport Proteins; Tissue Distribution

1998
Molecular cloning, expression and characterization of a bovine serotonin transporter.
    Brain research. Molecular brain research, 1999, Jul-23, Volume: 71, Issue:1

    Topics: Amino Acid Sequence; Animals; Carrier Proteins; Cattle; Citalopram; Cloning, Molecular; Desipramine; Female; Fluoxetine; HeLa Cells; Humans; Imipramine; Kinetics; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Sequence Data; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Tissue Proteins; Organ Specificity; Paroxetine; Phylogeny; Pregnancy; Rats; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Sequence Alignment; Sequence Homology, Amino Acid; Serotonin; Serotonin Plasma Membrane Transport Proteins; Transfection

1999
Safety of antidepressant use in pregnant and nursing women.
    JAMA, 1999, Jul-21, Volume: 282, Issue:3

    Topics: Antidepressive Agents; Breast Feeding; Depression, Postpartum; Depressive Disorder; Female; Humans; Infant, Newborn; Lactation; Paroxetine; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Risk; Selective Serotonin Reuptake Inhibitors; Sleep

1999
Behavioral changes in developing mice after prenatal exposure to paroxetine (Paxil)
    American journal of obstetrics and gynecology, 1999, Volume: 181, Issue:5 Pt 1

    Topics: Aggression; Animals; Animals, Newborn; Anxiety; Behavior, Animal; Body Weight; Depression; Exploratory Behavior; Female; Homing Behavior; Litter Size; Male; Maternal Exposure; Mice; Motor Activity; Paroxetine; Play and Playthings; Pregnancy; Prenatal Exposure Delayed Effects; Random Allocation; Selective Serotonin Reuptake Inhibitors; Sleep; Time Factors; Vocalization, Animal

1999
Paroxetine in human breast milk and nursing infants.
    The American journal of psychiatry, 2000, Volume: 157, Issue:2

    Topics: Breast Feeding; Chromatography, High Pressure Liquid; Depressive Disorder; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Infant, Newborn; Milk, Human; Paroxetine; Pregnancy; Puerperal Disorders

2000
Dose of selective serotonin uptake inhibitors across pregnancy: clinical implications.
    Depression and anxiety, 2000, Volume: 11, Issue:2

    Topics: Depressive Disorder, Major; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluoxetine; Humans; Infant, Newborn; Paroxetine; Pregnancy; Pregnancy Complications; Selective Serotonin Reuptake Inhibitors; Sertraline; Treatment Outcome

2000
The distribution of serotonergic nerves in microencephalic rats treated prenatally with methylazoxymethanol.
    Neurochemical research, 2000, Volume: 25, Issue:4

    Topics: Animals; Autoradiography; Binding Sites; Brain; Carrier Proteins; Cerebellum; Cerebral Cortex; Female; Hippocampus; Membrane Glycoproteins; Membrane Transport Proteins; Methylazoxymethanol Acetate; Microcephaly; Nerve Tissue Proteins; Neurons; Nucleus Accumbens; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Raphe Nuclei; Rats; Rats, Wistar; RNA, Messenger; Serotonin; Serotonin Plasma Membrane Transport Proteins; Thalamus

2000
Neurobiology of behavioral changes after prenatal exposure to paroxetine (Paxil)
    American journal of obstetrics and gynecology, 2000, Volume: 183, Issue:2

    Topics: Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Female; Mice; Nervous System; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects

2000
Nicotine exposure during pregnancy is a factor which influences serotonin transporter density in the rat brain.
    European journal of pharmacology, 2001, Jan-12, Volume: 411, Issue:3

    Topics: Animals; Brain Chemistry; Carrier Proteins; Female; Infusion Pumps; Injections, Subcutaneous; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Nicotine; Nicotinic Agonists; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins

2001
Withdrawal reactions of a premature neonate after maternal use of paroxetine.
    Archives of disease in childhood. Fetal and neonatal edition, 2001, Volume: 84, Issue:1

    Topics: Antidepressive Agents, Second-Generation; Female; Humans; Infant, Newborn; Infant, Premature; Neonatal Abstinence Syndrome; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Remission, Spontaneous

2001
Discontinuing antidepressants and benzodiazepines upon becoming pregnant. Beware of the risks of abrupt discontinuation.
    Canadian family physician Medecin de famille canadien, 2001, Volume: 47

    Topics: Anti-Anxiety Agents; Antidepressive Agents; Evidence-Based Medicine; Female; Humans; Informed Consent; Lorazepam; Paroxetine; Patient Education as Topic; Preconception Care; Pregnancy; Risk Factors; Safety; Substance Withdrawal Syndrome

2001
Serotonin reuptake inhibitor antidepressants and pregnancy: many unanswered questions.
    Prescrire international, 1999, Volume: 8, Issue:43

    Topics: Abnormalities, Drug-Induced; Antidepressive Agents, Second-Generation; Child; Child, Preschool; Clinical Trials as Topic; Depressive Disorder; Female; Fluoxetine; Fluvoxamine; Humans; Infant; Infant, Newborn; Paroxetine; Pregnancy; Selective Serotonin Reuptake Inhibitors; Sertraline; Treatment Outcome

1999
Alterations in serotonin transporter expression in brain regions of rats exposed neonatally to chlorpyrifos.
    Brain research. Developmental brain research, 2001, Sep-23, Volume: 130, Issue:1

    Topics: Animals; Animals, Newborn; Brain Chemistry; Carrier Proteins; Chlorpyrifos; Cholinesterase Inhibitors; Female; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Paroxetine; Pregnancy; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Tritium

2001
Fetal and adolescent nicotine administration: effects on CNS serotonergic systems.
    Brain research, 2001, Sep-28, Volume: 914, Issue:1-2

    Topics: Aging; Animals; Binding Sites; Brain; Carrier Proteins; Embryo, Mammalian; Female; Hydroxyindoleacetic Acid; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Degeneration; Nerve Tissue Proteins; Nicotine; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Presynaptic Terminals; Radioligand Assay; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Plasma Membrane Transport Proteins; Sex Characteristics; Synaptic Transmission; Tobacco Use Disorder

2001
5-HT3 receptor-active drugs alter development of spinal serotonergic innervation: lack of effect of other serotonergic agents.
    Brain research, 1992, Feb-07, Volume: 571, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Animals; Biguanides; Female; Fenfluramine; Hypoglycemic Agents; Maternal-Fetal Exchange; Neurons; Pain; Paroxetine; Piperazines; Piperidines; Pregnancy; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spinal Cord; Tetrahydronaphthalenes; Tropanes

1992
Prenatal cocaine exposure disrupts the development of the serotonergic system.
    Brain research, 1992, Feb-14, Volume: 572, Issue:1-2

    Topics: Animals; Animals, Newborn; Cocaine; Embryonic and Fetal Development; Female; Immunohistochemistry; Maternal-Fetal Exchange; Nerve Fibers; Neurons; Paroxetine; Piperidines; Pregnancy; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists

1992
High-affinity paroxetine binding to the human placental serotonin transporter.
    The American journal of physiology, 1990, Volume: 259, Issue:2 Pt 1

    Topics: 4-Chloro-7-nitrobenzofurazan; Binding, Competitive; Biological Transport; Carrier Proteins; Female; Humans; Imidazoles; Kinetics; Microvilli; Paroxetine; Piperidines; Placenta; Pregnancy; Serotonin; Serotonin Antagonists; Sodium; Tetranitromethane; Tyrosine

1990
Interaction of fluoxetine with the human placental serotonin transporter.
    Biochemical pharmacology, 1990, Nov-01, Volume: 40, Issue:9

    Topics: Carrier Proteins; Female; Fluoxetine; Humans; In Vitro Techniques; Microvilli; Paroxetine; Piperidines; Placenta; Pregnancy; Serotonin; Serotonin Antagonists

1990
Prenatal treatment with a selective D1 receptor agonist (SKF 38393) alters adult [3H]paroxetine binding and dopamine and serotonin behavioral sensitivity.
    Brain research. Developmental brain research, 1990, Dec-15, Volume: 57, Issue:2

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Behavior, Animal; Brain Stem; Cerebral Cortex; Conditioning, Operant; Dopamine; Female; Kinetics; Paroxetine; Piperidines; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Serotonin

1990
The reproductive toxicology of paroxetine.
    Acta psychiatrica Scandinavica. Supplementum, 1989, Volume: 350

    Topics: Abnormalities, Drug-Induced; Animals; Antidepressive Agents; Body Weight; Dose-Response Relationship, Drug; Female; Litter Size; Paroxetine; Piperidines; Pregnancy; Pregnancy, Animal; Rabbits; Rats; Serotonin Antagonists

1989