paroxetine and Aging
paroxetine has been researched along with Aging in 37 studies
Research
Studies (37)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.70) | 18.7374 |
| 1990's | 17 (45.95) | 18.2507 |
| 2000's | 12 (32.43) | 29.6817 |
| 2010's | 6 (16.22) | 24.3611 |
| 2020's | 1 (2.70) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Buck, LB; Petrascheck, M; Ye, X | 1 |
| Cui, P; Hao, L; He, X; Jia, Y; Liang, Z; Tong, B; Yang, F; Yuan, J; Zhao, L; Zhu, R | 1 |
| Liebl, C; Müller, MB; Scharf, SH; Schmidt, MV; Sterlemann, V | 1 |
| Dampney, B; Hunt, GE; Karanges, EA; Li, KM; McGregor, IS; Ramos, L; Suraev, AS | 1 |
| Ciliberto, M; De Crescenzo, F; Ebmeier, KP; Janiri, L; Menghini, D; Treglia, G | 1 |
| Bouzinova, EV; Finsen, B; Hasselstrøm, JB; Olesen, LØ; Severino, M; Sivasaravanaparan, M; Wiborg, O | 1 |
| Ellison, JM | 1 |
| Ershoff, BD; Lazzeroni, LC; Murphy, GM; Ryan, HS; Sarginson, JE; Schatzberg, AF | 1 |
| Callaghan, PD; Karanges, E; Katsifis, A; Li, KM; McGregor, IS; Motbey, C | 1 |
| Duncan, MJ; Hensler, JG | 1 |
| Duncan, MJ; Krajnak, K; Rosewell, KL; Wise, PM | 1 |
| Dew, MA; Houck, P; Lenze, EJ; Mulsant, BH; Pollock, BG; Reynolds, CF; Shear, MK | 1 |
| Brooks, SJ; Kutcher, S | 1 |
| Baroni, S; Carlini, M; Catena Dell'Osso, M; Consoli, G; Galassi, A; Giannaccini, G; Marazziti, D; Massimetti, G; Picchetti, M; Provenzano, S | 1 |
| Fartacek, R; Geretsegger, C; Heim, M; Mair, M; Platz, T; Stuppaeck, CH | 1 |
| Arranz, B; Eriksson, A; Marcusson, J; Mellerup, E; Plenge, P | 1 |
| Arora, RC; Crayton, JW; Gulati, A | 1 |
| Carroll, BJ; McCook, EC; Ritchie, JC; Seidler, FJ; Slotkin, TA | 1 |
| Huether, G; Rüther, E; Schmidt, S; Wiltfang, J; Zhou, D | 1 |
| Kamei, K; Kitera, K; Mikuni, M; Muneoka, K; Ogawa, T; Takahashi, K; Takigawa, M | 1 |
| McReynolds, AM; Meyer, JS | 1 |
| Barsanti, A; Carrai, M; Cassano, GB; Giannaccini, G; Lucacchini, A; Marazziti, D; Palego, L; Rossi, A; Serra, P | 1 |
| Cassano, GB; Giannaccini, G; Lucacchini, A; Marazziti, D; Masala, I; Mazzoni, M; Palego, L; Rossi, A; Rotondo, A | 1 |
| Kelly, PA; Noble, J; Olsson, T; Seckl, JR; Yau, JL | 1 |
| Bissette, G; Fumagalli, F; McCook, EC; Miller, DB; Seidler, FJ; Slotkin, TA; Zhang, J | 1 |
| Bagli, M; Huether, G; Moll, GH; Rothenberger, A; Rüther, E; Wegerer, V | 1 |
| Allard, P; Hägglöf, B; Mjörndal, T; Sigurdh, J; Spigset, O | 1 |
| Bock, N; Huether, G; Mehnert, C; Moll, GH; Rothenberger, A; Rüther, E; Wicker, M | 1 |
| Crafton, CJ; Duncan, MJ; Wheeler, DL | 1 |
| Dew, MA; Hernandez, CR; Houck, PR; Mulsant, B; Pollock, BG; Reynolds, CF; Smith, GS | 1 |
| Baroni, S; Cassano, GB; Giannaccini, G; Gori, V; Lucacchini, A; Marazziti, D; Masala, I; Rossi, A | 1 |
| Ali, SF; Seidler, FJ; Slikker, W; Slotkin, TA; Xu, Z | 1 |
| Andersson, A; Marcusson, J; Sundman, I | 1 |
| Dorman, T | 1 |
| Hindmarch, I | 1 |
| Bell, J; Whitaker-Azmitia, PM; Zhang, XN | 1 |
| Brunello, N; Galimberti, R; Racagni, G; Riva, M; Rovescalli, AC | 1 |
Reviews
2 review(s) available for paroxetine and Aging
| Article | Year |
|---|---|
Is
Topics: Aged; Aging; Blood Glucose; Brain; Case-Control Studies; Depression; Fluorodeoxyglucose F18; Humans; Paroxetine; Positron-Emission Tomography; Selective Serotonin Reuptake Inhibitors; Sensitivity and Specificity; Sleep Deprivation | 2017 |
A review of the psychomotor effects of paroxetine.
Topics: Adult; Aged; Aging; Depressive Disorder; Female; Humans; Male; Middle Aged; Paroxetine; Psychomotor Performance | 1992 |
Trials
8 trial(s) available for paroxetine and Aging
| Article | Year |
|---|---|
Agomelatine might be more appropriate for elderly, depressed, type 2 diabetes mellitus patients than paroxetine/fluoxetine.
Topics: Acetamides; Adult; Aged; Aging; Antidepressive Agents, Second-Generation; Depression; Diabetes Mellitus, Type 2; Female; Fluoxetine; Humans; Hypnotics and Sedatives; Male; Middle Aged; Paroxetine | 2021 |
Chronic social stress during adolescence: interplay of paroxetine treatment and ageing.
Topics: Adrenal Glands; Aging; Animals; Arginine Vasopressin; Body Weight; Chronic Disease; Corticosterone; Corticotropin-Releasing Hormone; Dexamethasone; Disease Models, Animal; Exploratory Behavior; Gene Expression Regulation; Longitudinal Studies; Male; Mice; Paroxetine; Receptors, Glucocorticoid; Selective Serotonin Reuptake Inhibitors; Social Isolation; Stress, Psychological; Thymus Gland | 2013 |
Good treatment outcomes in late-life depression with comorbid anxiety.
Topics: Age of Onset; Aged; Aged, 80 and over; Aging; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Anxiety Disorders; Combined Modality Therapy; Comorbidity; Depressive Disorder; Double-Blind Method; Female; Humans; Middle Aged; Nortriptyline; Paroxetine; Patient Dropouts; Prognosis; Psychotherapy; Treatment Outcome | 2003 |
The Kutcher Generalized Social Anxiety Disorder Scale for Adolescents: assessment of its evaluative properties over the course of a 16-week pediatric psychopharmacotherapy trial.
Topics: Adolescent; Aging; Antidepressive Agents, Second-Generation; Anxiety; Child; Depressive Disorder; Double-Blind Method; Female; Humans; Interpersonal Relations; Male; Paroxetine; Phobic Disorders; Psychiatric Status Rating Scales; Psychometrics; Reproducibility of Results; Sex Characteristics; Treatment Outcome | 2004 |
Multicenter double blind study of paroxetine and amitriptyline in elderly depressed inpatients.
Topics: Aged; Aging; Amitriptyline; Depression; Double-Blind Method; Female; Humans; Male; Paroxetine; Time Factors | 1995 |
Pharmacological characterization of the serotonin transporter in young and elderly subjects.
Topics: Adult; Aged; Aging; Antidepressive Agents, Tricyclic; Binding, Competitive; Blood Platelets; Carrier Proteins; Cell Membrane; Female; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Paroxetine; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins | 2001 |
Sleep and paroxetine: a comparison with mianserin in elderly depressed patients.
Topics: Aged; Aging; Depressive Disorder; Double-Blind Method; Humans; Mianserin; Paroxetine; Psychiatric Status Rating Scales; Sleep | 1992 |
A review of the psychomotor effects of paroxetine.
Topics: Adult; Aged; Aging; Depressive Disorder; Female; Humans; Male; Middle Aged; Paroxetine; Psychomotor Performance | 1992 |
Other Studies
28 other study(ies) available for paroxetine and Aging
| Article | Year |
|---|---|
An antidepressant that extends lifespan in adult Caenorhabditis elegans.
Topics: Aging; Animals; Antidepressive Agents; Caenorhabditis elegans; Caloric Restriction; Humans; Longevity; Methiothepin; Mianserin; Octopamine; Receptors, Biogenic Amine; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin 5-HT4 Receptor Antagonists; Serotonin Antagonists; Signal Transduction; Starvation | 2007 |
Contrasting regional Fos expression in adolescent and young adult rats following acute administration of the antidepressant paroxetine.
Topics: Age Factors; Aging; Analysis of Variance; Animals; Animals, Newborn; Antidepressive Agents; Brain; Corticosterone; Gene Expression Regulation, Developmental; Male; Oncogene Proteins v-fos; Paroxetine; Rats | 2016 |
Behavioural Phenotyping of APPswe/PS1δE9 Mice: Age-Rrelated Changes and Effect of Long-Term Paroxetine Treatment.
Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Cognition Disorders; Disease Models, Animal; Male; Maze Learning; Memory Disorders; Mice; Mice, Transgenic; Paroxetine; Presenilin-1; Social Behavior | 2016 |
A 60-year-old woman with mild memory impairment: review of mild cognitive impairment.
Topics: Aging; Alzheimer Disease; Cognition; Cognition Disorders; Counseling; Diagnosis, Differential; Diet; Female; Humans; Life Style; Magnetic Resonance Imaging; Memory Disorders; Middle Aged; Neurotransmitter Agents; Paroxetine; Positron-Emission Tomography; Psychotropic Drugs; Risk Factors | 2008 |
ABCB1 (MDR1) polymorphisms and antidepressant response in geriatric depression.
Topics: Aged; Aging; Antidepressive Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Depression; Female; Genotype; Humans; Japan; Male; Paroxetine; Polymorphism, Single Nucleotide; Survival Analysis; Treatment Outcome | 2010 |
Differential behavioural and neurochemical outcomes from chronic paroxetine treatment in adolescent and adult rats: a model of adverse antidepressant effects in human adolescents?
Topics: Adolescent; Aging; Animals; Antidepressive Agents; Behavior, Animal; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Humans; Male; Neurotransmitter Agents; Paroxetine; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Time Factors | 2011 |
Aging alters in a region-specific manner serotonin transporter sites and 5-HT(1A) receptor-G protein interactions in hamster brain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Animals; Autoradiography; Binding, Competitive; Brain; Carrier Proteins; Cricetinae; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Hippocampus; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mesocricetus; Nerve Tissue Proteins; Paroxetine; Piperazines; Pyridines; Raphe Nuclei; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins; Serotonin Receptor Agonists | 2002 |
Aging, estradiol and time of day differentially affect serotonin transporter binding in the central nervous system of female rats.
Topics: Aging; Animals; Autoradiography; Brain; Carrier Proteins; Central Nervous System; Circadian Rhythm; Estradiol; Female; Hippocampus; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Ovariectomy; Paraventricular Hypothalamic Nucleus; Paroxetine; Protein Binding; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Sleep; Suprachiasmatic Nucleus; Wakefulness | 2003 |
Thermal balneotherapy induces changes of the platelet serotonin transporter in healthy subjects.
Topics: Adult; Aging; Balneology; Blood Platelets; Female; Hot Temperature; Humans; Male; Middle Aged; Mineral Waters; Paroxetine; Reference Values; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Sex Characteristics | 2007 |
Effect of aging in human cortical pre- and postsynaptic serotonin binding sites.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adolescent; Adult; Aged; Aging; Binding Sites; Female; Frontal Lobe; Humans; Ketanserin; Male; Middle Aged; Paroxetine; Radioligand Assay; Serotonin; Synapses | 1993 |
Aging and 3H-paroxetine binding in rat brain: effect of imipramine and tetrahydroacridine.
Topics: Aging; Animals; Brain; Imipramine; Male; Paroxetine; Rats; Rats, Inbred F344; Tacrine; Tritium | 1993 |
Serotonin transporter expression in rat brain regions and blood platelets: aging and glucocorticoid effects.
Topics: Aging; Animals; Antidepressive Agents, Tricyclic; Blood Platelets; Brain Mapping; Carrier Proteins; Cerebral Cortex; Dexamethasone; Glucocorticoids; Hippocampus; Hypothalamo-Hypophyseal System; Imipramine; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Paroxetine; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Plasma Membrane Transport Proteins; Synaptosomes | 1997 |
Long-term food restriction down-regulates the density of serotonin transporters in the rat frontal cortex.
Topics: Aging; Animals; Body Weight; Carrier Proteins; Down-Regulation; Frontal Lobe; Male; Membrane Glycoproteins; Membrane Transport Proteins; Membranes; Mesencephalon; Nerve Tissue Proteins; Paroxetine; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Starvation | 1997 |
Prenatal dexamethasone exposure alters brain monoamine metabolism and adrenocortical response in rat offspring.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenal Cortex; Aging; Analysis of Variance; Animals; Biogenic Monoamines; Brain; Corticosterone; Defecation; Dexamethasone; Dopamine; Female; Gestational Age; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Motor Activity; Organ Specificity; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Serotonin | 1997 |
Effects of prenatal cocaine exposure on serotonin and norepinephrine transporter density in the rat brain.
Topics: Aging; Animals; Brain; Carrier Proteins; Cocaine; Female; Fluoxetine; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Organ Specificity; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Reference Values; Serotonin; Serotonin Plasma Membrane Transport Proteins; Symporters | 1998 |
Effect of aging and sex on the [3H]-paroxetine binding to human platelets.
Topics: Adult; Aged; Aged, 80 and over; Aging; Blood Platelets; Female; Humans; Male; Paroxetine; Selective Serotonin Reuptake Inhibitors; Sex Characteristics | 1998 |
Regulation of the platelet serotonin transporter by protein kinase C in the young and elderly.
Topics: Adult; Aged; Aged, 80 and over; Aging; Binding Sites; Blood Platelets; Carrier Proteins; Enzyme Activation; Female; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Paroxetine; Protein Kinase C; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Tetradecanoylphorbol Acetate | 1999 |
Chronic amitriptyline administration increases serotonin transporter binding sites in the hippocampus of aged rats.
Topics: Aging; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Binding Sites; Carrier Proteins; Dentate Gyrus; Hippocampus; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Paroxetine; Rats; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Up-Regulation | 1999 |
Modeling geriatric depression in animals: biochemical and behavioral effects of olfactory bulbectomy in young versus aged rats.
Topics: Adenylyl Cyclases; Aging; Animals; Antidepressive Agents, Second-Generation; Avoidance Learning; Behavior, Animal; Body Weight; Brain; Carrier Proteins; Depressive Disorder; In Vitro Techniques; Male; Membrane Glycoproteins; Membrane Transport Proteins; Motor Activity; Nerve Tissue Proteins; Olfactory Bulb; Paroxetine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Reflex, Startle; RNA, Messenger; Serotonin; Serotonin Plasma Membrane Transport Proteins | 1999 |
Persistently increased density of serotonin transporters in the frontal cortex of rats treated with fluoxetine during early juvenile life.
Topics: Aging; Animals; Behavior, Animal; Brain Chemistry; Carrier Proteins; Fluoxetine; Growth; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Paroxetine; Prefrontal Cortex; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins | 1999 |
Binding of [(3)H]lysergic acid diethylamide to serotonin 5-HT(2A) receptors and of [(3)H]paroxetine to serotonin uptake sites in platelets from healthy children, adolescents and adults.
Topics: Adolescent; Adult; Aging; Binding Sites; Blood Platelets; Child; Female; Humans; Lysergic Acid Diethylamide; Male; Paroxetine; Receptors, Serotonin; Reference Values; Selective Serotonin Reuptake Inhibitors; Serotonin Agents | 1999 |
Age-associated changes in the densities of presynaptic monoamine transporters in different regions of the rat brain from early juvenile life to late adulthood.
Topics: Aging; Animals; Brain; Brain Stem; Carrier Proteins; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Female; Fluoxetine; Frontal Lobe; Ligands; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mesencephalon; Nerve Tissue Proteins; Norepinephrine Plasma Membrane Transport Proteins; Paroxetine; Piperazines; Presynaptic Terminals; Protein Binding; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Symporters; Tritium | 2000 |
Aging regulates 5-HT(1B) receptors and serotonin reuptake sites in the SCN.
Topics: Aging; Animals; Autoradiography; Brain; Cricetinae; Iodine Radioisotopes; Iodocyanopindolol; Kinetics; Male; Mesocricetus; Paroxetine; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Serotonin; Suprachiasmatic Nucleus; Tritium | 2000 |
The clinical response to total sleep deprivation and recovery sleep in geriatric depression: potential indicators of antidepressant treatment outcome.
Topics: Aged; Aging; Antidepressive Agents, Second-Generation; Combined Modality Therapy; Depression; Depressive Disorder, Major; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Paroxetine; Predictive Value of Tests; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Sleep Deprivation; Treatment Outcome | 2000 |
Fetal and adolescent nicotine administration: effects on CNS serotonergic systems.
Topics: Aging; Animals; Binding Sites; Brain; Carrier Proteins; Embryo, Mammalian; Female; Hydroxyindoleacetic Acid; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Degeneration; Nerve Tissue Proteins; Nicotine; Paroxetine; Pregnancy; Prenatal Exposure Delayed Effects; Presynaptic Terminals; Radioligand Assay; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Plasma Membrane Transport Proteins; Sex Characteristics; Synaptic Transmission; Tobacco Use Disorder | 2001 |
Age stability of human brain 5-HT terminals studied with [3H]paroxetine binding.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Binding Sites; Biological Transport, Active; Brain; Child; Child, Preschool; Female; Humans; In Vitro Techniques; Infant; Infant, Newborn; Kinetics; Male; Middle Aged; Paroxetine; Piperidines; Serotonin; Serotonin Antagonists; Sex Characteristics | 1992 |
5-HT3 receptor-active drugs alter development of spinal serotonergic innervation: lack of effect of other serotonergic agents.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Animals; Biguanides; Female; Fenfluramine; Hypoglycemic Agents; Maternal-Fetal Exchange; Neurons; Pain; Paroxetine; Piperazines; Piperidines; Pregnancy; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spinal Cord; Tetrahydronaphthalenes; Tropanes | 1992 |
Age-related changes in rat serotonergic and adrenergic systems and in receptor responsiveness to subchronic desipramine treatment.
Topics: Aging; Animals; Brain; Clonidine; Desipramine; Dihydroalprenolol; Hydroxyindoleacetic Acid; Imipramine; Ketanserin; Kinetics; Male; Paroxetine; Piperidines; Prazosin; Proteins; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Serotonin; Serotonin; Time Factors | 1988 |