paromomycin has been researched along with Black Fever in 96 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 17 (17.71) | 18.2507 |
2000's | 20 (20.83) | 29.6817 |
2010's | 48 (50.00) | 24.3611 |
2020's | 11 (11.46) | 2.80 |
Authors | Studies |
---|---|
Boykin, DW; Hall, JE; Kyle, DE; Liu, Q; Madhubala, R; Mandal, S; Munde, M; Pandharkar, T; Parman, T; Riccio, E; Srivastava, A; Stephens, CE; Sweat, JM; Tidwell, RR; Wang, MZ; Werbovetz, KA; Wilson, WD; Zhu, X | 1 |
Blaser, A; Braillard, S; Chatelain, E; Cooper, CB; Denny, WA; Franzblau, SG; Gupta, S; Launay, D; Ma, Z; Maes, L; Marshall, AJ; O'Connor, PD; Thompson, AM; Wan, B; Yardley, V | 1 |
Atnafu, S; Hailu, A; Medhin, G; Mohammed, R; Tamiru, A | 1 |
Abdella, AM; Dessie, G; Endale, HT; Malik, T; Mengstie, TA; Mohammed, R; Mulaw, T | 1 |
Coelho, AC; Coser, EM; Cotrim, PC; da L Oliveira, V; Ferreira, BA; Martins, TFC; Pinto, MM; Rocha, MC; Yamashiro-Kanashiro, EH | 1 |
Alcoba, G; Alvar, J; Alves, F; Dorlo, TPC; Egondi, T; Fikre, H; Ismail Omer Haroun, A; Khalil, EAG; Mbui, J; Mekonnen, T; Mersha, D; Mohammed, R; Musa Younis, B; Musa, AM; Muthoni Ouattara, G; Nakanwagi, P; Njenga, S; Nour, A; Olobo, J; Omollo, T; Ritmeijer, K; Sagaki, P; Sisay, K; Solomos, A; Taha Ahmed Elmukashfi, E; Verrest, L; Wasunna, M | 1 |
Alves, F; Beijnen, JH; Dorlo, TPC; Musa, AM; Roseboom, IC; Rosing, H; Thijssen, B; Younis, BM | 1 |
Henriquez-Figuereo, A; Moreno, E; Plano, D; Sanmartin, C | 1 |
Alves, F; Chu, WY; Dorlo, TPC; Huitema, ADR; Mbui, J; Mohammed, R; Musa, AM; Njenga, S; Olobo, J; Ritmeijer, K; Roseboom, IC; Solomos, A; Verrest, L; Wasunna, M | 1 |
Apostolidis, K; Buono, A; Chatzis, MK; Kasabalis, D; Leontides, LS; Petanides, T; Polizopoulou, ZS; Saridomichelakis, MN; Steiner, JM; Suchodolski, JS; Xenoulis, PG | 1 |
Alvar, J; Alves, F; Bern, C; Burza, S; Das, P; Das, VNR; Goyal, V; Hightower, A; Lima, N; Pandey, K; Rijal, S; Singh, RS; Singh, SN; Strub-Wourgaft, N; Sunyoto, T | 1 |
Berriman, M; Blackburn, G; Carter, KC; Coombs, GH; Cotton, JA; Downing, T; Dujardin, JC; Imamura, H; Rijal, S; Sanders, M; Shaw, CD; Westrop, GD | 1 |
Beijnen, JH; Dorlo, TPC; Mbui, J; Roseboom, IC; Rosing, H; Thijssen, B | 1 |
Apostolidis, K; Athanasiou, LV; Chatzis, MK; Ikonomopoulos, J; Kasabalis, D; Leontides, LS; Mataragka, A; Petanides, T; Saridomichelakis, MN; Xenoulis, PG | 1 |
Gedda, MR; Mudavath, SL; Parvez, S; Singh, A; Singh, OP; Sundar, S; Verma, A; Yadagiri, G | 1 |
Alves, F; Aman, R; Beijnen, JH; Chakravarty, J; Dorlo, TPC; Hailu, A; Hailu, W; Huitema, ADR; Hurissa, Z; Khalil, EAG; Kokwaro, G; Kshirsagar, SA; Makonnen, E; Mekonnen, Y; Mudawi, M; Musa, AM; Rai, M; Sundar, S; Tesfaye, S; Verrest, L; Wasunna, M; Younis, BM | 1 |
Asensi-Diez, R; Furones Araujo, D; Gallego Fernández, C | 1 |
Caljon, G; Cos, P; Delputte, P; Hendrickx, S; Mabille, D; Maes, L; Van den Kerkhof, M | 1 |
Alvar, J; Alves, F; Balasegaram, M; Boer, MD; Ellis, S; Faiz, A; Goyal, V; Haque, R; Jamil, K; Rahman, R; Rijal, S; Samad, R; Sharma, B; Strub-Wourgaft, N | 1 |
Arrese Estrada, J; Cnops, L; Darcis, G; de Leval, L; Giot, JB; Hayette, MP; Leonard, P; Moutschen, M; Tassin, F; Van der Auwera, G | 1 |
Bhandari, V; Deep, DK; Dujardin, JC; Salotra, P; Singh, R; Sundar, S; Verma, A | 1 |
Fernando, SD; Rajapakse, S; Rodrigo, C; Weeratunga, P | 1 |
Singh, A; Sundar, S | 1 |
Ahuja, V; Ghosh, P; Haque, R; Hossain, AFMA; Hossain, MA; Hossain, MS; Kumar, A; Mahshin, M; Maruf, S; Mondal, D; Shamsuzzaman, AKM; Sharma, A; Sharma, V | 1 |
Alvar, J; Alves, F; Balasegaram, M; Bern, C; Burza, S; Das, P; Ellis, S; Goyal, V; Hightower, A; Lima, N; Mahajan, R; Pandey, K; Rabi Das, VN; Rijal, S; Sharma, B; Singh, RS; Singh, SN; Strub-Wourgaft, N; Sunyoto, T; Topno, RK | 1 |
Alvar, J; Boelaert, M; Das, P; Mondal, D; Rijal, S; Sundar, S | 1 |
Afzal, I; Akhtar, S; Jahan, S; Sarwar, HS; Satoskar, AR; Shahnaz, G; Sohail, MF; Varikuti, S; Yasinzai, M | 1 |
Agarwal, N; Arya, SC | 1 |
Das, P; Das, S; Pandey, K; Rabidas, V; Rani, M; Sahoo, GC | 1 |
Ben Messaoud, N; Ben Salah, A; Buffet, PA; Grogl, M; Kidar, A; Kopydlowski, KM; Kreishman-Deitrick, M; Morizot, G; Nielsen, CJ; Novitt-Moreno, A; Ransom, JH; Smith, PL; Zaâtour, A | 1 |
Assefa, A; Belew, Z; Boelaert, M; Diro, E; Gebregziabiher, B; Hailu, A; Lakew, W; Lynen, L; van Griensven, J | 1 |
Cos, P; Delputte, P; Eberhardt, E; Hendrickx, S; Maes, L; Mondelaers, A | 1 |
Alcoba, G; Alnour, M; Atia, AM; Boulle, P; Chappuis, F; Elhag, MS; Mumina, A; Shah, S; Tayler-Smith, K; van Griensven, J; Zachariah, R | 1 |
Cos, P; Delputte, P; Dujardin, JC; Hendrickx, S; Khanal, B; Leemans, A; Maes, L; Mondelaers, A; Rijal, S | 1 |
Bhuiyan, AT; Bhuiyan, MA; Desjeux, P; Dhalaria, P; Faiz, MA; Ghosh, RS; Haque, R; Hassan, SM; Jamil, KM; Kelly, H; Khan, MM; Kochhar, S; Kumar, A; Rahman, R | 1 |
Beyers, J; Cos, P; Delputte, P; Eberhardt, E; Hendrickx, S; Lachaud, L; Maes, L; Mondelaers, A | 1 |
Alvar, J; Balasegaram, M; Hailu, A; Juma, R; Khalil, EA; Musa, A; Olobo, J; Wasunna, M; Wells, S | 1 |
Ali, V; Bimal, S; Das, P; Das, VNR; Lal, CS; Murti, K; Pal, B; Pandey, K; Siddiqi, NA; Topno, RK; Verma, N; Verma, RB | 1 |
Alirol, E; Alvar, J; Alves, F; Balasegaram, M; Chappuis, F; Diro, E; Ellis, S; Hailu, A; Jameneh, A; Khalil, EA; Kimutai, R; Makonnen, E; Mohammed, R; Musa, AM; Musa, B; Njoroge, S; Okello, L; Olobo, J; Omollo, R; Rashid, J; Ritmeijer, K; Sagaki, P; Salman, K; Soipei, P; Strub, N; Wasunna, M | 1 |
Thakur, CP | 1 |
Davidson, RN; den Boer, M; Ritmeijer, K | 1 |
Olliaro, P; Sundar, S | 1 |
Darley, S; Laxminarayan, R; Olliaro, P; Sundar, S | 1 |
Agarwal, D; Agrawal, N; Arora, R; Chakravarty, J; Rai, M; Sundar, S | 1 |
Khan, W; Kumar, N | 1 |
Barragán, P; López-Velez, R; Olmo, M; Podzamczer, D | 1 |
Balasegaram, M; Boelaert, M; Faiz, MA; Meheus, F; Olliaro, P; Rijal, S; Sundar, S | 1 |
Gupta, S; Sane, SA; Shakya, N | 1 |
Murray, HW | 2 |
Olliaro, PL | 1 |
Ahmed, O; Alobo, M; Balasegaram, M; Edwards, T; El-Hassan, A; Ellis, S; Fadlalla, A; Hailu, A; Hailu, W; Hurissa, Z; Kesusu, J; Khalil, E; Kinuthia, J; Kirigi, G; Kirui, F; Koummuki, Y; Lodenyo, H; Makonnen, E; Manduku, V; Mbui, J; Mengistu, G; Mucee, G; Mueller, M; Musa, A; Musibi, A; Mutea, D; Muthami, L; Mutuma, G; Njoroge, S; Omollo, R; Owiti, R; Raheem, M; Rashid, J; Royce, C; Smith, P; Tesfaye, S; Wasunna, M; Weldegebreal, T; Yifru, S | 1 |
Balasegaram, M; Edwards, T; El-Hassan, A; Fadlalla, A; Hailu, A; Khalil, E; Kokwaro, G; Mudawi, M; Musa, AM; Omollo, R; Royce, C; Wasunna, M; Younis, B | 1 |
Ali, N; Banerjee, A; De, M | 1 |
Alam, S; Arora, R; Balasegaram, M; Chakravarty, J; Das, P; Ellis, S; Kumari, P; Lal, CS; Modabber, F; Nawin, K; Olliaro, P; Pandey, K; Rai, M; Sharma, B; Sinha, PK; Strub-Wourgaft, N; Sundar, S; Vaillant, M; Verma, DK; Verma, N | 1 |
Boelaert, M; van Griensven, J | 1 |
Alvar, J; Arana, B; Battacharya, S; Das, P; Kroeger, A; Matlashewski, G; Mondal, D; Rijal, S; Sinha, PK; Sundar, S; Zilberstein, D | 1 |
Croft, SL; Olliaro, P | 1 |
Bimal, S; Das, P; Das, S; Das, VN; Lal, CS; Pandey, K; Siddiqui, NA; Singh, D; Sinha, PK; Topno, RK; Verma, N; Verma, RB | 1 |
Arora, SK; Khan, W; Kumar, N; Kumar, R; Singh, S | 1 |
Bhandari, V; Deep, DK; Dujardin, JC; Kulshrestha, A; Prajapati, VK; Ramesh, V; Salotra, P; Schonian, G; Stark, O; Sundar, S | 1 |
Bhandari, V; Carter, K; Cos, P; Dujardin, JC; Hendrickx, S; Inocêncio da Luz, RA; Kuypers, K; Lonchamp, J; Maes, L; Rijal, S; Salotra, P; Shaw, CD; Sundar, S | 1 |
Abuzaid, AA; Ahmed, O; Apadet, L; Balasegaram, M; Edwards, T; El-Hassan, A; Ellis, S; Fadlalla, A; Hailu, A; Hailu, W; Hurissa, Z; Kesusu, J; Khalil, E; Kimutai, R; Kirigi, G; Lodenyo, H; Makonnen, E; Manduku, V; Mbui, J; Mekonnen, Y; Mengistu, G; Mucee, G; Mueller, M; Musa, A; Musa, B; Mutea, D; Mutuma, G; Ndegwa, S; Njoroge, S; Olobo, J; Omollo, R; Owiti, R; Rashid, J; Sagaki, P; Tafes, H; Wasunna, M; Weldegebreal, T; Yifru, S | 1 |
Athanasiou, LV; Kontos, VI; Rallis, TS; Saridomichelakis, MN; Spanakos, G | 1 |
Chakravarty, J; Sundar, S | 1 |
Boelaert, M; Bryceson, AD; Croft, SL; Desjeux, P; Guerin, PJ; Olliaro, P; Sundar, S; Wasunna, MK | 1 |
Carter, KC; Mullen, AB; Pereira, OC; Spickett, C; Sundar, S | 1 |
Desjeux, P | 1 |
Kumar, A; Sundar, S | 1 |
Pandey, HP; Singh, RK; Sundar, S | 1 |
Croft, SL; Seifert, K; Yardley, V | 1 |
Hu, LT; Klempner, MS; Unnasch, TR | 1 |
Bhattacharya, SK; Jha, TK; Sinha, PK; Sundar, S; Thakur, CP | 1 |
Collin, SM; Davidson, RN; Gatluak, F; Keus, K; Melaku, Y; Ritmeijer, K | 1 |
Hale, V | 1 |
Calza, L; Manfredi, R; Marinacci, G; Passarini, B | 1 |
Baat, DB; Hassan, K; Hassan, M | 1 |
Boer, C; Davidson, R; de Jong, J; de Wilde, E; Seaman, J; Sondorp, E; Wilkinson, R | 1 |
Allen, S; Croft, SL; McCoy, N; Neal, RA; Olliaro, P | 1 |
Bryceson, AD; Davidson, RN; Moody, A; Pryce, D; Seaman, J; Sondorp, HE | 1 |
Buffet, PA; Derouin, F; Garin, YJ; Nassar, N; Sulahian, A | 1 |
Bandinelli, P; Guidi, G; Mancianti, F; Poli, A; Sozzi, S | 1 |
Derouin, F; Gangneux, JP; Garin, YJ; Sulahian, A | 1 |
del Giudice, P; Dellamonica, P; Haas, H; Lacour, JP; Le Fichoux, Y; Marty, P; Perrin, C; Pratlong, F | 1 |
Cavalcante, R; Fonseca de Castro, JA; Furtado Campos, JH; Miles, MA; Olliaro, PL; Tavares, JP; Vexenat, JA | 1 |
Akhoury, S; Jha, S; Jha, TK; Kanyok, TP; Olliaro, P; Singh, IJ; Singh, NK; Singhania, BL; Thakur, CP | 1 |
Ciaramella, P; Cortese, L; de Luna, R; Gradoni, L; Oliva, G; Orsini, S; Persechino, A; Scalone, A | 1 |
Craciunescu, DG; Loiseau, PM; Mbongo, N; Robert-Gero, M | 1 |
Jha, TK; Olliaro, P | 1 |
Baillie, AJ; Carter, KC; Mullen, AB; Williams, D | 1 |
Belloli, C; Bertini, S; Carli, S; Crescenzo, G; Mengozzi, G; Ormas, P; Zaghini, A | 1 |
Murray , HW | 1 |
Sundar, S | 2 |
Zijlstra, EE | 1 |
14 review(s) available for paromomycin and Black Fever
Article | Year |
---|---|
Amphotericin B for treatment of visceral leishmaniasis: systematic review and meta-analysis of prospective comparative clinical studies including dose-ranging studies.
Topics: Amphotericin B; Antiprotozoal Agents; Clinical Trials as Topic; Deoxycholic Acid; Drug Combinations; Drug Compounding; Evidence-Based Medicine; Female; Humans; Leishmaniasis, Visceral; Male; Paromomycin; Phosphorylcholine; Survival Analysis; Treatment Outcome | 2018 |
Chemotherapeutics of visceral leishmaniasis: present and future developments.
Topics: Amphotericin B; Animals; Antiprotozoal Agents; Clinical Trials as Topic; Drug Resistance, Multiple; Drug Therapy, Combination; HIV Infections; Humans; India; Leishmania donovani; Leishmaniasis, Visceral; Meglumine Antimoniate; Paromomycin; Phosphorylcholine; Psychodidae; Sheep; South America; Treatment Outcome | 2018 |
Paromomycin.
Topics: Animals; Anti-Bacterial Agents; Antiprotozoal Agents; Communicable Diseases, Emerging; Drug Resistance; Humans; Leishmaniasis, Visceral; Paromomycin | 2009 |
Drug combinations for visceral leishmaniasis.
Topics: Amphotericin B; Antimony Sodium Gluconate; Antiprotozoal Agents; Cost-Benefit Analysis; Drug Resistance; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Leishmaniasis, Visceral; Paromomycin; Phosphorylcholine | 2010 |
Visceral leishmaniasis: elimination with existing interventions.
Topics: Amphotericin B; Antiprotozoal Agents; Communicable Disease Control; Drug Therapy, Combination; Humans; Leishmaniasis, Visceral; Paromomycin; Phosphorylcholine | 2011 |
Leishmaniasis chemotherapy--challenges and opportunities.
Topics: Anti-HIV Agents; Antiprotozoal Agents; Clinical Trials as Topic; Coinfection; Drug Discovery; HIV; HIV Infections; Humans; India; Leishmania; Leishmaniasis, Cutaneous; Leishmaniasis, Visceral; Paromomycin; Research | 2011 |
Leishmaniasis: an update of current pharmacotherapy.
Topics: Amphotericin B; Antimony Sodium Gluconate; Antiprotozoal Agents; Drug Therapy, Combination; Humans; Leishmania donovani; Leishmaniasis, Visceral; Meglumine; Meglumine Antimoniate; Organometallic Compounds; Parasitic Sensitivity Tests; Paromomycin; Phosphorylcholine; Practice Guidelines as Topic; Species Specificity; Treatment Outcome | 2013 |
Visceral leishmaniasis: current status of control, diagnosis, and treatment, and a proposed research and development agenda.
Topics: Aminoquinolines; Animals; Antiprotozoal Agents; Asia, Western; Brazil; Developing Countries; Dogs; Female; Humans; Leishmaniasis, Visceral; Male; Paromomycin; Phosphorylcholine; Sudan | 2002 |
Progress in the treatment of a neglected infectious disease: visceral leishmaniasis.
Topics: Amphotericin B; Antimony; Antiprotozoal Agents; Clinical Trials as Topic; Deoxycholic Acid; Drug Combinations; Drug Costs; Humans; Leishmaniasis, Visceral; Paromomycin; Phosphatidylcholines; Phosphatidylglycerols; Phosphorylcholine; Practice Guidelines as Topic | 2004 |
Visceral leishmaniasis (kala-azar): challenges ahead.
Topics: Aminoquinolines; Amphotericin B; Animals; Antimony; Antiprotozoal Agents; Drug Resistance; Enzyme-Linked Immunosorbent Assay; Humans; India; Leishmania; Leishmaniasis, Visceral; Lipids; Paromomycin; Public Health; Sensitivity and Specificity | 2006 |
Current scenario of drug development for leishmaniasis.
Topics: Amphotericin B; Animals; Antiprotozoal Agents; Drug Design; Humans; Leishmania; Leishmaniasis; Leishmaniasis, Cutaneous; Leishmaniasis, Visceral; Models, Chemical; Paromomycin; Phosphorylcholine | 2006 |
Cutaneous leishmaniasis due to Leishmania infantum. Case reports and literature review.
Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Animals; Anti-Bacterial Agents; Antigens, Protozoan; Antiprotozoal Agents; Blotting, Western; Child, Preschool; Female; Follow-Up Studies; Humans; Infant; Injections, Intradermal; Leishmania infantum; Leishmaniasis, Cutaneous; Leishmaniasis, Visceral; Male; Meglumine; Middle Aged; Paromomycin | 1998 |
Treatment of visceral leishmaniasis (kala-azar): a decade of progress and future approaches.
Topics: Adult; Amphotericin B; Animals; Antimony; Antiprotozoal Agents; Child; Humans; Leishmania donovani; Leishmaniasis, Visceral; Mice; Paromomycin; Phosphorylcholine; Treatment Outcome | 2000 |
Treatment of visceral leishmaniasis.
Topics: Administration, Oral; Amphotericin B; Antiprotozoal Agents; Humans; Leishmaniasis, Visceral; Paromomycin; Pentamidine | 2001 |
22 trial(s) available for paromomycin and Black Fever
Article | Year |
---|---|
Paromomycin and Miltefosine Combination as an Alternative to Treat Patients With Visceral Leishmaniasis in Eastern Africa: A Randomized, Controlled, Multicountry Trial.
Topics: Adult; Africa, Eastern; Antimony Sodium Gluconate; Antiprotozoal Agents; Child; Drug Therapy, Combination; Humans; Leishmaniasis, Visceral; Paromomycin; Phosphorylcholine; Treatment Outcome | 2023 |
Population pharmacokinetics of a combination of miltefosine and paromomycin in Eastern African children and adults with visceral leishmaniasis.
Topics: Adult; Antiprotozoal Agents; Child; Humans; Kenya; Leishmaniasis, Visceral; Paromomycin; Phosphorylcholine; Treatment Outcome; Uganda | 2023 |
Evaluation of nephrotoxicity and ototoxicity of aminosidine (paromomycin)-allopurinol combination in dogs with leishmaniosis due to Leishmania infantum: A randomized, blinded, controlled study.
Topics: Allopurinol; Animals; Cochlea; Creatinine; Dog Diseases; Dogs; Double-Blind Method; Drug Combinations; Evoked Potentials, Auditory, Brain Stem; Female; Hearing; Hearing Loss; Injections, Subcutaneous; Kidney; Leishmania infantum; Leishmaniasis, Visceral; Male; Meglumine Antimoniate; Neurologic Examination; Paromomycin; Random Allocation; Vestibule, Labyrinth | 2019 |
A randomized, blinded, controlled clinical trial comparing the efficacy of aminosidine (paromomycin)-allopurinol combination with the efficacy of meglumine antimoniate-allopurinol combination for the treatment of canine leishmaniosis due to Leishmania inf
Topics: Allopurinol; Animals; Dog Diseases; Dogs; Drug Therapy, Combination; Female; Injections, Subcutaneous; Leishmania infantum; Leishmaniasis, Visceral; Male; Meglumine Antimoniate; Paromomycin; Trypanocidal Agents | 2020 |
Safety and efficacy of short course combination regimens with AmBisome, miltefosine and paromomycin for the treatment of visceral leishmaniasis (VL) in Bangladesh.
Topics: Adolescent; Adult; Amphotericin B; Antiprotozoal Agents; Bangladesh; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Leishmaniasis, Visceral; Male; Middle Aged; Paromomycin; Phosphorylcholine; Recurrence; Treatment Outcome; Young Adult | 2017 |
Field safety and effectiveness of new visceral leishmaniasis treatment regimens within public health facilities in Bihar, India.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amphotericin B; Antiprotozoal Agents; Child; Child, Preschool; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Female; Humans; India; Leishmaniasis, Visceral; Male; Middle Aged; Paromomycin; Phosphorylcholine; Prospective Studies; Treatment Outcome; Young Adult | 2018 |
TLR9 and MyD88 are crucial for the maturation and activation of dendritic cells by paromomycin-miltefosine combination therapy in visceral leishmaniasis.
Topics: Adult; Antiprotozoal Agents; Cells, Cultured; Dendritic Cells; Drug Combinations; Female; HEK293 Cells; Humans; Interleukin-10; Interleukin-12; Leishmaniasis, Visceral; Male; Myeloid Differentiation Factor 88; Paromomycin; Phosphorylcholine; Toll-Like Receptor 9 | 2014 |
Parasite load decrease during application of a safe and easily applied antileishmanial aminoglycoside cream.
Topics: Administration, Topical; Adolescent; Adult; Aged; Dermis; Drug Combinations; Female; Gentamicins; Humans; Leishmania donovani; Leishmaniasis, Visceral; Male; Middle Aged; Parasite Load; Paromomycin; Trypanocidal Agents; Young Adult | 2014 |
Effectiveness Study of Paromomycin IM Injection (PMIM) for the Treatment of Visceral Leishmaniasis (VL) in Bangladesh.
Topics: Adolescent; Adult; Anti-Infective Agents; Bangladesh; Child; Child, Preschool; Drug-Related Side Effects and Adverse Reactions; Female; Health Care Costs; Humans; Injections, Intramuscular; Leishmaniasis, Visceral; Male; Middle Aged; Paromomycin; Treatment Outcome; Young Adult | 2015 |
Safety and efficacy of a combination of paromomycin and miltefosine for two vs. three courses in patients with post-kala-azar dermal leishmaniasis: an observational pilot study.
Topics: Administration, Oral; Adult; Antiprotozoal Agents; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Injections, Intramuscular; Leishmaniasis, Cutaneous; Leishmaniasis, Visceral; Male; Paromomycin; Phosphorylcholine; Pilot Projects; Treatment Outcome | 2017 |
Short-course paromomycin treatment of visceral leishmaniasis in India: 14-day vs 21-day treatment.
Topics: Adolescent; Adult; Animals; Antiprotozoal Agents; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; India; Injections, Intramuscular; Leishmaniasis, Visceral; Male; Middle Aged; Paromomycin; Time Factors; Treatment Outcome; Young Adult | 2009 |
Geographical variation in the response of visceral leishmaniasis to paromomycin in East Africa: a multicentre, open-label, randomized trial.
Topics: Adolescent; Adult; Africa, Eastern; Antiprotozoal Agents; Child; Child, Preschool; Female; Geography; Humans; Leishmania donovani; Leishmaniasis, Visceral; Male; Middle Aged; Paromomycin; Treatment Outcome; Young Adult | 2010 |
Paromomycin for the treatment of visceral leishmaniasis in Sudan: a randomized, open-label, dose-finding study.
Topics: Adolescent; Adult; Antiprotozoal Agents; Bone Marrow; Child; Child, Preschool; Female; Humans; Injections, Intramuscular; Leishmania donovani; Leishmaniasis, Visceral; Male; Microscopy; Middle Aged; Paromomycin; Sudan; Time Factors; Treatment Outcome; Young Adult | 2010 |
Comparison of short-course multidrug treatment with standard therapy for visceral leishmaniasis in India: an open-label, non-inferiority, randomised controlled trial.
Topics: Adolescent; Adult; Amphotericin B; Antiprotozoal Agents; Child; Child, Preschool; Creatinine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Hemoglobins; Humans; India; Leishmaniasis, Visceral; Liver; Liver Function Tests; Male; Middle Aged; Paromomycin; Phosphorylcholine; Recurrence; Young Adult | 2011 |
Sodium stibogluconate (SSG) & paromomycin combination compared to SSG for visceral leishmaniasis in East Africa: a randomised controlled trial.
Topics: Adolescent; Adult; Africa, Eastern; Antimony Sodium Gluconate; Antiprotozoal Agents; Child; Child, Preschool; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Leishmaniasis, Visceral; Male; Middle Aged; Paromomycin; Treatment Outcome; Young Adult | 2012 |
Treatment of canine leishmaniosis with aminosidine at an optimized dosage regimen: a pilot open clinical trial.
Topics: Animals; Antibodies, Protozoan; Antiprotozoal Agents; Bone Marrow; DNA, Protozoan; Dog Diseases; Dogs; Drug Dosage Calculations; Female; Fluorescent Antibody Technique, Indirect; Injections, Subcutaneous; Leishmania infantum; Leishmaniasis, Visceral; Lymph Nodes; Male; Paromomycin; Pilot Projects; Polymerase Chain Reaction; Treatment Outcome | 2013 |
Injectable paromomycin for Visceral leishmaniasis in India.
Topics: Adolescent; Adult; Amphotericin B; Animals; Antiprotozoal Agents; Audiometry; Child; Child, Preschool; Disease Reservoirs; Female; Hearing Disorders; Humans; India; Infusions, Intravenous; Injections, Intramuscular; Kidney Diseases; Leishmania donovani; Leishmaniasis, Visceral; Male; Middle Aged; Paromomycin; Prospective Studies; Treatment Outcome | 2007 |
Liposomal amphotericin B (AmBisome) in the treatment of complicated kala-azar under field conditions.
Topics: Adolescent; Adult; Aged; Amebicides; Amphotericin B; Animals; Anti-Bacterial Agents; Antimony; Child; Child, Preschool; Drug Administration Schedule; Drug Carriers; Female; Humans; Infant; Leishmania donovani; Leishmania infantum; Leishmaniasis, Visceral; Liposomes; Lymph Nodes; Male; Middle Aged; Paromomycin; Recurrence; Spleen; Sudan | 1995 |
Epidemic visceral leishmaniasis in Sudan: a randomized trial of aminosidine plus sodium stibogluconate versus sodium stibogluconate alone.
Topics: Adolescent; Adult; Antimony Sodium Gluconate; Child; Child, Preschool; Disease Outbreaks; Drug Therapy, Combination; Female; Giardiasis; Humans; Infant; Leishmaniasis, Visceral; Malaria; Male; Middle Aged; Nutrition Disorders; Paromomycin; Pregnancy; Sudan; Weight Loss | 1993 |
Comparison of aminosidine (paromomycin) and sodium stibogluconate for treatment of canine leishmaniasis.
Topics: Amebicides; Animals; Antibodies, Protozoan; Antigen-Antibody Complex; Antigens, Protozoan; Antimony Sodium Gluconate; Antiprotozoal Agents; Dog Diseases; Dogs; Female; Immunoglobulin G; Leishmania infantum; Leishmaniasis, Visceral; Male; Paromomycin; Proteinuria; Time Factors | 1997 |
Randomised controlled trial of aminosidine (paromomycin) v sodium stibogluconate for treating visceral leishmaniasis in North Bihar, India.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Antimony Sodium Gluconate; Child; Dose-Response Relationship, Drug; Humans; Injections, Intramuscular; Leishmaniasis, Visceral; Middle Aged; Paromomycin; Risk Assessment; Schistosomicides; Treatment Outcome | 1998 |
The treatment of kala-azar: old and new options.
Topics: Amphotericin B; Antimony; Humans; Ketoconazole; Leishmaniasis, Visceral; Paromomycin | 1992 |
60 other study(ies) available for paromomycin and Black Fever
Article | Year |
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Novel arylimidamides for treatment of visceral leishmaniasis.
Topics: Amidines; Animals; Antiprotozoal Agents; Biological Availability; Cricetinae; Disease Models, Animal; Drug Discovery; Female; Furans; Humans; In Vitro Techniques; Leishmania donovani; Leishmania major; Leishmania mexicana; Leishmaniasis, Visceral; Liver; Mesocricetus; Mice; Mice, Inbred BALB C; Microsomes, Liver; Mutagenicity Tests; Parasitemia; Parasitic Sensitivity Tests; Spleen; Tissue Distribution | 2010 |
Development of (6 R)-2-Nitro-6-[4-(trifluoromethoxy)phenoxy]-6,7-dihydro-5 H-imidazo[2,1- b][1,3]oxazine (DNDI-8219): A New Lead for Visceral Leishmaniasis.
Topics: Animals; Antiparasitic Agents; Cell Membrane Permeability; Chagas Disease; Cricetinae; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; ERG1 Potassium Channel; Leishmania donovani; Leishmania infantum; Leishmaniasis, Visceral; Mesocricetus; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Oxazines; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship | 2018 |
Efficacy and safety of a combined treatment of sodium stibogluconate at 20mg/kg/day with upper maximum daily dose limit of 850mg and Paromomycin 15mg/kg/day in HIV negative visceral leishmaniasis patients. A retrospective study, northwest Ethiopia.
Topics: Adolescent; Adult; Antimony Sodium Gluconate; Antiprotozoal Agents; Child; Child, Preschool; Drug Dosage Calculations; Drug Therapy, Combination; Ethiopia; Female; Humans; Leishmaniasis, Visceral; Male; Middle Aged; Paromomycin; Retrospective Studies; Treatment Outcome; Young Adult | 2021 |
Assessment of serum amylase, lipase and associated factors among patients with visceral leishmaniasis treated with sodium stibogluconate/paromomycin at University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia.
Topics: Adolescent; Adult; Amylases; Antimony Sodium Gluconate; Antiprotozoal Agents; Cross-Sectional Studies; Ethiopia; Female; Hospitals, Special; Humans; Leishmaniasis, Visceral; Lipase; Male; Paromomycin; Treatment Outcome; Young Adult | 2021 |
Isolation, typing, and drug susceptibility of Leishmania (Leishmania) infantum isolates from dogs of the municipality of Embu das Artes, an endemic region for canine leishmaniasis in Brazil.
Topics: Animals; Brazil; Dog Diseases; Dogs; Humans; Leishmania infantum; Leishmaniasis, Visceral; Paromomycin | 2022 |
Development and validation of an ultra-high performance liquid chromatography coupled to tandem mass spectrometry method for the quantification of the antileishmanial drug paromomycin in human skin tissue.
Topics: Antiprotozoal Agents; Chromatography, High Pressure Liquid; Humans; Leishmaniasis, Visceral; Paromomycin; Reproducibility of Results; Tandem Mass Spectrometry | 2022 |
Exploring Novel Drug Combinations: The Therapeutic Potential of Selanyl Derivatives for Leishmania Treatment.
Topics: Amphotericin B; Animals; Antiprotozoal Agents; Drug Combinations; Humans; Leishmania infantum; Leishmaniasis, Visceral; Mice; Mice, Inbred BALB C; Paromomycin | 2023 |
Field effectiveness of new visceral leishmaniasis regimens after 1 year following treatment within public health facilities in Bihar, India.
Topics: Adolescent; Amphotericin B; Antiprotozoal Agents; Child; Child, Preschool; Cohort Studies; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; India; Leishmaniasis, Visceral; Male; Paromomycin; Phosphorylcholine; Recurrence; Treatment Outcome | 2019 |
Genomic and Metabolomic Polymorphism among Experimentally Selected Paromomycin-Resistant Leishmania donovani Strains.
Topics: Animals; Antiprotozoal Agents; Drug Resistance; Female; Genomics; Humans; Leishmania donovani; Leishmaniasis, Visceral; Lipidomics; Macrophages; Metabolomics; Mice; Mice, Inbred BALB C; Nepal; Parasitic Sensitivity Tests; Paromomycin; Polymorphism, Genetic | 2019 |
Highly sensitive UPLC-MS/MS method for the quantification of paromomycin in human plasma.
Topics: Adsorption; Africa, Eastern; Antiprotozoal Agents; Calibration; Chromatography, High Pressure Liquid; Drug Monitoring; Drug Stability; Humans; Injections, Intramuscular; Leishmaniasis, Visceral; Limit of Detection; Paromomycin; Reference Standards; Reproducibility of Results; Tandem Mass Spectrometry; Trichloroacetic Acid | 2020 |
Modified solid lipid nanoparticles encapsulated with Amphotericin B and Paromomycin: an effective oral combination against experimental murine visceral leishmaniasis.
Topics: Amphotericin B; Animals; Antiprotozoal Agents; Cell Line; Emulsions; Leishmania donovani; Leishmaniasis, Visceral; Lipids; Male; Mice; Mice, Inbred BALB C; Microscopy, Electron, Transmission; Nanoparticles; Paromomycin; Particle Size; Phosphorylcholine | 2020 |
Geographical Variability in Paromomycin Pharmacokinetics Does Not Explain Efficacy Differences between Eastern African and Indian Visceral Leishmaniasis Patients.
Topics: Antimony Sodium Gluconate; Antiprotozoal Agents; Humans; Kenya; Leishmaniasis, Visceral; Paromomycin | 2021 |
[Hearing loss associated with paromomycin treatment in a patient with visceral leishmaniasis].
Topics: Adult; Antiparasitic Agents; Hearing Loss; Humans; Leishmaniasis, Visceral; Male; Paromomycin | 2017 |
Combined treatment of miltefosine and paromomycin delays the onset of experimental drug resistance in Leishmania infantum.
Topics: Animals; Antiprotozoal Agents; Cricetinae; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Leishmania infantum; Leishmaniasis, Visceral; Mice; Paromomycin; Phosphorylcholine | 2017 |
Recurrence of visceral and muco-cutaneous leishmaniasis in a patient under immunosuppressive therapy.
Topics: Amphotericin B; Antiprotozoal Agents; Biopsy; Female; Humans; Immunocompromised Host; Leishmania; Leishmaniasis, Cutaneous; Leishmaniasis, Visceral; Macrophages; Middle Aged; Paromomycin; Phosphorylcholine; Polymerase Chain Reaction; Recurrence | 2017 |
Transcriptome profiling identifies genes/pathways associated with experimental resistance to paromomycin in Leishmania donovani.
Topics: Amlodipine; Animals; Anti-Bacterial Agents; Antimony; Antiprotozoal Agents; ATP-Binding Cassette Transporters; Drug Resistance; Gene Expression Profiling; Humans; Leishmania donovani; Leishmaniasis, Visceral; Life Cycle Stages; Macrophages; Metabolic Networks and Pathways; Mice; Nitric Oxide; Parasitic Sensitivity Tests; Paromomycin; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Verapamil | 2017 |
Using focused pharmacovigilance for ensuring patient safety against antileishmanial drugs in Bangladesh's National Kala-azar Elimination Programme.
Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Amphotericin B; Antiprotozoal Agents; Bangladesh; Female; Humans; Leishmania donovani; Leishmania tropica; Leishmaniasis, Cutaneous; Leishmaniasis, Visceral; Male; Middle Aged; Myocardial Infarction; Paromomycin; Patient Safety; Pharmacovigilance; Phosphorylcholine; Quality of Life; Recurrence; Survival Analysis | 2018 |
Eliminating visceral leishmaniasis in South Asia: the road ahead.
Topics: Amphotericin B; Animals; Antiprotozoal Agents; Bangladesh; Disease Vectors; Drug Therapy, Combination; Epidemiological Monitoring; Humans; India; International Cooperation; Leishmaniasis, Visceral; Neglected Diseases; Nepal; Paromomycin; Phosphorylcholine; Program Development; Program Evaluation | 2019 |
Mannosylated thiolated paromomycin-loaded PLGA nanoparticles for the oral therapy of visceral leishmaniasis.
Topics: Animals; Antiprotozoal Agents; Cells, Cultured; Flow Cytometry; Lectins, C-Type; Leishmania donovani; Leishmaniasis, Visceral; Mannose Receptor; Mannose-Binding Lectins; Mice; Mice, Inbred BALB C; Nanoparticles; Paromomycin; Receptors, Cell Surface | 2019 |
Comment on: leishmaniasis: an update of current pharmacotherapy.
Topics: Amphotericin B; Antiprotozoal Agents; Humans; Leishmaniasis, Visceral; Organometallic Compounds; Paromomycin; Phosphorylcholine | 2013 |
Clinical aspects of paediatric visceral leishmaniasis in North-west Ethiopia.
Topics: Amebicides; Amphotericin B; Antimony Sodium Gluconate; Antiprotozoal Agents; Child; Child, Preschool; Comorbidity; Cross-Sectional Studies; Ethiopia; Female; HIV Infections; Humans; Intestinal Diseases, Parasitic; Leishmaniasis, Visceral; Male; Malnutrition; Paromomycin; Prospective Studies; Treatment Outcome; Vitamin D Deficiency | 2015 |
In Vivo Selection of Paromomycin and Miltefosine Resistance in Leishmania donovani and L. infantum in a Syrian Hamster Model.
Topics: Animals; Antiprotozoal Agents; Cricetinae; Disease Models, Animal; Drug Resistance; Female; Leishmania donovani; Leishmania infantum; Leishmaniasis, Visceral; Parasitic Sensitivity Tests; Paromomycin; Phosphorylcholine | 2015 |
Sodium stibogluconate and paromomycin for treating visceral leishmaniasis under routine conditions in eastern Sudan.
Topics: Adolescent; Adult; Anemia; Antimony Sodium Gluconate; Antiprotozoal Agents; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Leishmaniasis, Visceral; Lost to Follow-Up; Male; Malnutrition; Paromomycin; Patient Selection; Prevalence; Recurrence; Retrospective Studies; Sudan; Treatment Failure | 2015 |
Comparative Fitness of a Parent Leishmania donovani Clinical Isolate and Its Experimentally Derived Paromomycin-Resistant Strain.
Topics: Animals; Antiprotozoal Agents; Drug Resistance; Female; Genetic Fitness; In Vitro Techniques; Leishmania donovani; Leishmaniasis, Visceral; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Paromomycin | 2015 |
Evidence of a drug-specific impact of experimentally selected paromomycin and miltefosine resistance on parasite fitness in Leishmania infantum.
Topics: Animals; Antiprotozoal Agents; Disease Models, Animal; Drug Resistance; Female; Humans; Leishmania infantum; Leishmaniasis, Visceral; Mice, Inbred BALB C; Paromomycin; Phosphorylcholine; Selection, Genetic; Virulence | 2016 |
The Leishmaniasis East Africa Platform (LEAP): strengthening clinical trial capacity in resource-limited countries to deliver new treatments for visceral leishmaniasis.
Topics: Africa, Eastern; Antimony Sodium Gluconate; Antiprotozoal Agents; Biomedical Research; Capacity Building; Cooperative Behavior; Endemic Diseases; Humans; Leishmaniasis, Visceral; Neglected Diseases; Paromomycin | 2016 |
Safety and Effectiveness of Sodium Stibogluconate and Paromomycin Combination for the Treatment of Visceral Leishmaniasis in Eastern Africa: Results from a Pharmacovigilance Programme.
Topics: Administration, Intravenous; Adolescent; Adult; Africa, Eastern; Antimony Sodium Gluconate; Antiprotozoal Agents; Child; Child, Preschool; Coinfection; Drug Therapy, Combination; Female; HIV Infections; Humans; Leishmaniasis, Visceral; Male; Middle Aged; Paromomycin; Pharmacovigilance; Prospective Studies; Recurrence; Treatment Outcome; Young Adult | 2017 |
Tetany in kala azar patients treated with paromomycin.
Topics: Adolescent; Anti-Bacterial Agents; Calcium; Child; Child, Preschool; Female; Humans; Leishmaniasis, Visceral; Male; Paromomycin; Randomized Controlled Trials as Topic; Tetany | 2008 |
Anthropometrically derived dosing and drug costing calculations for treating visceral leishmaniasis in Bihar, India.
Topics: Adolescent; Adult; Age Distribution; Aged; Amphotericin B; Anthropometry; Antiprotozoal Agents; Body Weight; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Costs; Female; Humans; India; Infant; Leishmaniasis, Visceral; Liposomes; Male; Middle Aged; Paromomycin; Phosphorylcholine; Sex Distribution | 2009 |
Cost-effectiveness projections of single and combination therapies for visceral leishmaniasis in Bihar, India.
Topics: Adolescent; Adult; Amphotericin B; Antiprotozoal Agents; Child; Cost-Benefit Analysis; Direct Service Costs; Drug Administration Schedule; Drug Costs; Female; Hospital Costs; Humans; India; Leishmaniasis, Visceral; Male; Paromomycin; Phosphorylcholine; Practice Guidelines as Topic; Young Adult | 2009 |
Drug targeting to macrophages using paromomycin-loaded albumin microspheres for treatment of visceral leishmaniasis: an in vitro evaluation.
Topics: Albumins; Animals; Antiprotozoal Agents; Cell Line; Drug Carriers; Drug Delivery Systems; Leishmania donovani; Leishmaniasis, Visceral; Mice; Microspheres; Paromomycin | 2011 |
Visceral Leishmaniasis treated with antimonials/paromomycin followed by itraconazole/miltefosine after standard therapy failures in a human immunodeficiency virus-infected patient.
Topics: AIDS-Related Opportunistic Infections; HIV; HIV Infections; HIV-1; Humans; Itraconazole; Leishmaniasis; Leishmaniasis, Cutaneous; Leishmaniasis, Visceral; Opportunistic Infections; Parasitic Sensitivity Tests; Paromomycin; Phosphorylcholine; Recurrence; Treatment Failure | 2010 |
Cost-effectiveness analysis of combination therapies for visceral leishmaniasis in the Indian subcontinent.
Topics: Amphotericin B; Antiprotozoal Agents; Bangladesh; Cost-Benefit Analysis; Drug Therapy, Combination; Humans; India; Leishmaniasis, Visceral; Models, Statistical; Nepal; Paromomycin; Phosphorylcholine | 2010 |
Immunomodulatory effect of picroliv on the efficacy of paromomycin and miltefosine in combination in experimental visceral leishmaniasis.
Topics: Animals; Antiprotozoal Agents; Cell Proliferation; Cinnamates; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Glycosides; Leishmania donovani; Leishmaniasis, Visceral; Lymphocytes; Male; Mesocricetus; Paromomycin; Phagocytosis; Phosphorylcholine; Random Allocation; Reactive Nitrogen Species; Reactive Oxygen Species; Vanillic Acid | 2011 |
Treatment of visceral leishmaniasis in 2010: direction from Bihar State, India.
Topics: Amphotericin B; Animals; Antiprotozoal Agents; Drug Therapy, Combination; Humans; India; Leishmania donovani; Leishmaniasis, Visceral; Paromomycin; Phosphorylcholine; Treatment Outcome | 2010 |
Combination therapy with paromomycin-associated stearylamine-bearing liposomes cures experimental visceral leishmaniasis through Th1-biased immunomodulation.
Topics: Amines; Animals; Anti-Bacterial Agents; Cells, Cultured; Cricetinae; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Immunity, Humoral; Immunologic Factors; Interleukin-10; Leishmaniasis, Visceral; Liposomes; Mice; Mice, Inbred BALB C; Paromomycin; Phosphatidylcholines; Transforming Growth Factor beta | 2011 |
Combination therapy for visceral leishmaniasis.
Topics: Amphotericin B; Antiprotozoal Agents; Drug Administration Schedule; Drug Therapy, Combination; Humans; India; Leishmaniasis, Visceral; Paromomycin; Phosphorylcholine; Randomized Controlled Trials as Topic | 2011 |
Post-kala-azar dermal leishmaniasis in a patient treated with injectable paromomycin for visceral leishmaniasis in India.
Topics: Adult; Antiprotozoal Agents; Female; Humans; Leishmania donovani; Leishmaniasis, Cutaneous; Leishmaniasis, Visceral; Paromomycin; Secondary Prevention | 2012 |
Paromomycin-loaded albumin microspheres: efficacy and stability studies.
Topics: Albumins; Amebicides; Animals; Cells, Cultured; Drug Carriers; Drug Delivery Systems; Drug Stability; Humans; Leishmania donovani; Leishmaniasis, Visceral; Macrophages; Mice; Mice, Inbred BALB C; Microspheres; Paromomycin | 2013 |
Drug susceptibility in Leishmania isolates following miltefosine treatment in cases of visceral leishmaniasis and post kala-azar dermal leishmaniasis.
Topics: Adolescent; Adult; Animals; Antiprotozoal Agents; Child; Female; Humans; India; Inhibitory Concentration 50; Leishmania donovani; Leishmaniasis, Cutaneous; Leishmaniasis, Visceral; Macrophages; Male; Middle Aged; Parasitic Sensitivity Tests; Paromomycin; Phosphorylcholine; Young Adult | 2012 |
Experimental induction of paromomycin resistance in antimony-resistant strains of L. donovani: outcome dependent on in vitro selection protocol.
Topics: Animals; Antimony; Antiprotozoal Agents; Cricetinae; Drug Resistance; Genomic Instability; Humans; India; Inhibitory Concentration 50; Leishmania donovani; Leishmaniasis, Visceral; Mesocricetus; Mice; Mice, Inbred BALB C; Nepal; Parasitic Sensitivity Tests; Parasitology; Paromomycin; Selection, Genetic; Serial Passage | 2012 |
The in vivo susceptibility of Leishmania donovani to sodium stibogluconate is drug specific and can be reversed by inhibiting glutathione biosynthesis.
Topics: Amphotericin B; Animals; Antimony Sodium Gluconate; Buthionine Sulfoximine; Drug Resistance; Female; Glutathione; Leishmania donovani; Leishmaniasis, Visceral; Male; Mice; Mice, Inbred BALB C; Paromomycin; Phosphorylcholine | 2003 |
[Therapeutic options for visceral leishmaniasis].
Topics: Aminoquinolines; Amphotericin B; Antiprotozoal Agents; Humans; Leishmaniasis, Visceral; Paromomycin | 2005 |
Challenges in the management of visceral leishmaniasis.
Topics: Amebicides; Amphotericin B; Antimony Sodium Gluconate; Antiparasitic Agents; Antiprotozoal Agents; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique, Indirect; Humans; Immunoglobulin G; Leishmaniasis, Visceral; Paromomycin; Pentamidine; Phosphorylcholine | 2005 |
Taking a bite out of vector-transmitted infectious diseases.
Topics: Animals; Antiprotozoal Agents; Communicable Disease Control; Communicable Diseases; Disease Reservoirs; Disease Transmission, Infectious; Disease Vectors; Humans; Leishmaniasis, Visceral; Paromomycin; Psychodidae; Vaccines | 2007 |
Treatment of kala-azar in southern Sudan using a 17-day regimen of sodium stibogluconate combined with paromomycin: a retrospective comparison with 30-day sodium stibogluconate monotherapy.
Topics: Adolescent; Antimony Sodium Gluconate; Antiprotozoal Agents; Child; Child, Preschool; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Infant; Infant, Newborn; Leishmaniasis, Visceral; Male; Medical Records; Paromomycin; Retrospective Studies; Sudan; Treatment Outcome | 2007 |
Straight talk from... Victoria Hale.
Topics: Academies and Institutes; Drug Industry; Humans; Leishmaniasis, Visceral; Organizations, Nonprofit; Paromomycin | 2007 |
Diffuse cutaneous dissemination of visceral leishmaniasis during human immunodeficiency virus (HIV) infection, despite negligible immunodeficiency: repeated failure of liposomal amphotericin B administration, followed by successful long-term pentamidine a
Topics: Adult; Amphotericin B; Antiprotozoal Agents; Drug Carriers; HIV Infections; Humans; Leishmaniasis, Visceral; Liposomes; Male; Paromomycin; Pentamidine; Treatment Failure | 2008 |
A new breakthrough in treatment of visceral leishmaniasis in children.
Topics: Anemia; Animals; Anti-Bacterial Agents; Antiprotozoal Agents; Child; Child, Preschool; Female; Fever; Follow-Up Studies; Hepatomegaly; Humans; Infant; Injections, Intramuscular; Leishmania donovani; Leishmaniasis, Visceral; Leukocyte Count; Male; Pakistan; Paromomycin; Platelet Count; Splenomegaly | 1995 |
The sensitivity of Leishmania species to aminosidine.
Topics: Animals; Antimony Sodium Gluconate; Cells, Cultured; Cricetinae; Drug Combinations; Drug Interactions; Female; Leishmania; Leishmania donovani; Leishmaniasis, Visceral; Macrophages, Peritoneal; Male; Mesocricetus; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Microbial Sensitivity Tests; Paromomycin | 1995 |
Therapeutic effect of reference antileishmanial agents in murine visceral leishmaniasis due to Leishmania infantum.
Topics: Amphotericin B; Animals; Antiprotozoal Agents; Female; Leishmania infantum; Leishmaniasis, Visceral; Liver Diseases, Parasitic; Lung Diseases, Parasitic; Meglumine; Meglumine Antimoniate; Mice; Mice, Inbred BALB C; Organometallic Compounds; Parasitology; Paromomycin; Splenic Diseases | 1996 |
Efficacy of aminosidine administered alone or in combination with meglumine antimoniate for the treatment of experimental visceral leishmaniasis caused by Leishmania infantum.
Topics: Animals; Antiprotozoal Agents; Disease Models, Animal; Drug Therapy, Combination; Female; Leishmania infantum; Leishmaniasis, Visceral; Liver; Meglumine; Meglumine Antimoniate; Mice; Mice, Inbred BALB C; Organometallic Compounds; Paromomycin; Spleen | 1997 |
Clinical recovery and limited cure in canine visceral leishmaniasis treated with aminosidine (paromomycin).
Topics: Animals; Antiprotozoal Agents; Disease Reservoirs; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Leishmaniasis, Visceral; Paromomycin; Recurrence; Treatment Outcome | 1998 |
Comparative efficacy of meglumine antimoniate and aminosidine sulphate, alone or in combination, in canine leishmaniasis.
Topics: Animals; Antiprotozoal Agents; Dog Diseases; Dogs; Drug Therapy, Combination; Leishmania infantum; Leishmaniasis, Visceral; Meglumine; Meglumine Antimoniate; Organometallic Compounds; Paromomycin; Treatment Outcome | 1998 |
Synergistic effect of Ir-(COT)-pentamidine alizarin red and pentamidine, amphotericin B, and paromomycin on Leishmania donovani.
Topics: Amphotericin B; Animals; Antiprotozoal Agents; Drug Synergism; Female; Iridium; Leishmania donovani; Leishmaniasis, Visceral; Macrophages; Mice; Mice, Inbred BALB C; Organometallic Compounds; Paromomycin; Pentamidine; Random Allocation | 1998 |
Clarification of comments on trial of aminosidine in visceral leishmaniasis.
Topics: Anti-Bacterial Agents; Antimony; Drug Costs; Drug Therapy, Combination; Humans; Leishmaniasis, Visceral; Paromomycin | 1998 |
Comparison of the efficacy of free and non-ionic-surfactant vesicular formulations of paromomycin in a murine model of visceral leishmaniasis.
Topics: Animals; Antiprotozoal Agents; Chemistry, Pharmaceutical; Disease Models, Animal; Drug Delivery Systems; Drug Evaluation, Preclinical; Female; Leishmania donovani; Leishmaniasis, Visceral; Mice; Mice, Inbred BALB C; Paromomycin; Surface-Active Agents; Treatment Outcome | 1998 |
Drug watch.
Topics: Administration, Inhalation; Amebicides; Antimony Sodium Gluconate; Antiprotozoal Agents; Diabetes Mellitus, Type 1; Humans; Insulin; Leishmaniasis, Visceral; Paromomycin | 1998 |
Disposition of antimony and aminosidine combination after multiple subcutaneous injections in dogs.
Topics: Amebicides; Animals; Antimony; Antiprotozoal Agents; Area Under Curve; Chromatography, Liquid; Dog Diseases; Dogs; Drug Therapy, Combination; Female; Fluorometry; Half-Life; Injections, Subcutaneous; Least-Squares Analysis; Leishmania infantum; Leishmaniasis, Visceral; Male; Meglumine; Meglumine Antimoniate; Organometallic Compounds; Paromomycin; Spectrophotometry, Atomic | 1999 |
Drug resistance in Indian visceral leishmaniasis.
Topics: Aminoquinolines; Amphotericin B; Antimony; Antiprotozoal Agents; Dose-Response Relationship, Drug; Drug Resistance; Geography; History, 20th Century; History, 21st Century; Humans; India; Leishmaniasis, Visceral; Paromomycin; Pentamidine; Phosphorylcholine; Treatment Outcome | 2001 |