pargyline has been researched along with Pregnancy in 48 studies
Pargyline: A monoamine oxidase inhibitor with antihypertensive properties.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This model of peripheral aromatization was utilized to evaluate in vivo pharmacological parameters of MDL 18,962 (10-(2-propynyl)estr-4-ene-3,17-dione) such as bioavailability of several formulations, time course and dose responses following different routes of drug administration, pharmacokinetics and tissue distribution of [14C]MDL 18,962." | 1.28 | Human trophoblast xenografts in athymic mice: a model for peripheral aromatization. ( Johnston, JO; Shumaker, RC; Wright, CL, 1989) |
| "[3H]Pargyline has been covalently linked to active sites of both type A and type B monoamine oxidase (MAO) obtained from various tissues." | 1.26 | Studies on the pargyline-binding site of different types of monoamine oxidase. ( Yu, PH, 1981) |
| "[3H]Pargyline was bound to MAO A in a crude mitochondrial fraction from the placental trophoblast of a male newborn and to MAO B in blood platelets from the umbilical vein of the same newborn." | 1.26 | Differences in the structure of A and B forms of human monoamine oxidase. ( Breakefield, XO; Cawthon, RM; Haseltine, FP; Pintar, JE, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 42 (87.50) | 18.7374 |
| 1990's | 4 (8.33) | 18.2507 |
| 2000's | 1 (2.08) | 29.6817 |
| 2010's | 1 (2.08) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Szkilnik, R | 1 |
| Brus, R | 1 |
| Malinowska-Borowska, J | 1 |
| Nowak, D | 1 |
| Waliczek, M | 1 |
| Kostrzewa, RM | 1 |
| Nowak, P | 1 |
| Larsen, TR | 1 |
| Rossen, S | 1 |
| Gramsbergen, JB | 1 |
| Meyerson, BJ | 5 |
| Waldmann, EB | 1 |
| Nickas, G | 1 |
| Dörner, G | 2 |
| Walker, RF | 1 |
| Johnston, JO | 2 |
| Wright, CL | 2 |
| Metcalf, BW | 1 |
| Yu, PH | 1 |
| Phillippe, M | 1 |
| Niloff, JM | 1 |
| Koike, K | 1 |
| Aono, T | 1 |
| Chatani, F | 1 |
| Takemura, T | 1 |
| Kurachi, K | 1 |
| Cawthon, RM | 1 |
| Pintar, JE | 1 |
| Haseltine, FP | 1 |
| Breakefield, XO | 1 |
| Brown, GK | 1 |
| Powell, JF | 1 |
| Craig, IW | 1 |
| Zheng, MQ | 1 |
| Reum, T | 1 |
| Morgenstern, R | 1 |
| Pons, C | 1 |
| Dansette, PM | 1 |
| Gregeois, J | 1 |
| Homberg, JC | 1 |
| Billett, EE | 1 |
| Mansuy, D | 1 |
| Hernández, RJ | 1 |
| Breese, GR | 1 |
| Vogel, RA | 1 |
| Kuhn, CM | 1 |
| Mailman, RB | 1 |
| Mueller, RA | 1 |
| Schanberg, SM | 1 |
| Hinz, G | 1 |
| Döcke, F | 1 |
| Tönjes, R | 1 |
| Rajaofetra, N | 1 |
| Poulat, P | 1 |
| Marlier, L | 1 |
| Geffard, M | 1 |
| Privat, A | 1 |
| Mistry, AM | 1 |
| Vidal, G | 1 |
| Voogt, JL | 1 |
| Cohen, ML | 1 |
| Wittenauer, LA | 1 |
| di Salle, E | 1 |
| Briatico, G | 1 |
| Giudici, D | 1 |
| Ornati, G | 1 |
| Zaccheo, T | 1 |
| Borisova, NA | 1 |
| Gallant, KR | 1 |
| Cherian, MG | 1 |
| Riley, LA | 1 |
| Waguespack, MA | 1 |
| Denney, RM | 2 |
| Shumaker, RC | 1 |
| Riley, L | 1 |
| Brandt, ME | 1 |
| Puett, D | 1 |
| Covey, DF | 1 |
| Zimniski, SJ | 1 |
| Cohen, G | 1 |
| Mytilineou, C | 1 |
| Sadovsky, E | 3 |
| Weinstein, D | 1 |
| Pfeifer, Y | 6 |
| Polishuk, WZ | 1 |
| Sulman, FG | 6 |
| King, CT | 1 |
| Horigan, E | 1 |
| Wilk, AL | 1 |
| Carrer, H | 1 |
| Eliasson, M | 1 |
| Loo, YH | 1 |
| Murphy, DL | 1 |
| Donnelly, CH | 1 |
| Polishuk, WA | 1 |
| Harrison, TS | 1 |
| Freier, DT | 1 |
| Cohen, EL | 1 |
| Huidobro, F | 1 |
| Tamayo, L | 1 |
| Contreras, E | 1 |
| Ratner, A | 1 |
| McCann, SM | 1 |
| Sawyer, CH | 1 |
| Lindström, LH | 1 |
| Lewander, T | 1 |
| Polishuk, Z | 1 |
| Lippmann, W | 1 |
| Sadowsky, E | 1 |
| Koren, Z | 3 |
2 reviews available for pargyline and Pregnancy
| Article | Year |
|---|---|
Sex hormones and neurotransmitters as mediators for sexual differentiation of the brain.
Topics: Acetylcholinesterase; Androgens; Animals; Avoidance Learning; Brain; Castration; Disorders of Sex De | 1981 |
Monoamine oxidase in man: enzyme characteristics in platelets, plasma, and other human tissues.
Topics: Age Factors; Benzyl Compounds; Bipolar Disorder; Blood Platelets; Brain; Cyanides; Diseases in Twins | 1974 |
46 other studies available for pargyline and Pregnancy
| Article | Year |
|---|---|
Ontogenetic manganese exposure with perinatal 6-OHDA lesioning alters behavioral responses of rats to dopamine D₁ and D2 agonist treatments.
Topics: Animals; Behavior, Animal; Desipramine; Dopamine; Dopamine Agonists; Exploratory Behavior; Female; H | 2014 |
Dopamine release in organotypic cultures of foetal mouse mesencephalon: effects of depolarizing agents, pargyline, nomifensine, tetrodotoxin and calcium.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Calcium; Dopamine; Dopamine Uptake Inhibitors; Female; Fetu | 2008 |
Oestrous behaviour in oestrogen treated ovariectomized rats after chlorpromazine alone or in combination with progesterone, tetrabenazine or reserpine.
Topics: Animals; Body Temperature; Castration; Chlorpromazine; Drug Antagonism; Drug Synergism; Estradiol; E | 1966 |
Pargyline hydrochloride combined with methyclothiazide in the treatment of hypertension.
Topics: Adult; Aged; Drug Synergism; Female; Humans; Hypertension; Male; Methyclothiazide; Middle Aged; Parg | 1967 |
Reinstatement of LH surges by serotonin neuroleptics in aging, constant estrous rats.
Topics: 5-Hydroxytryptophan; Aging; alpha-Methyltyrosine; Animals; Antipsychotic Agents; Castration; Estradi | 1982 |
Time-dependent inhibition of aromatase in trophoblastic tumor cells in tissue culture.
Topics: Androstenedione; Aromatase Inhibitors; Cell Line; Choriocarcinoma; Estrogens; Female; Humans; Kineti | 1984 |
Studies on the pargyline-binding site of different types of monoamine oxidase.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cattle; Clorgyline; Female; Humans; In Vitro Techniques | 1981 |
Metabolism of 3H-dopamine by human chorioamnion in vitro.
Topics: 3-Methoxy-4-hydroxyphenylethanol; 3,4-Dihydroxyphenylacetic Acid; Chromatography, Ion Exchange; Dopa | 1982 |
Improved method for determination of catecholamines in rat brain by isolation on boric acid gel and high-performance liquid chromatography with electrochemical detection.
Topics: Animals; Boric Acids; Brain Chemistry; Catecholamines; Chromatography, Gel; Chromatography, High Pre | 1982 |
Differences in the structure of A and B forms of human monoamine oxidase.
Topics: Adult; Binding Sites; Blood Platelets; Cell Line; Female; Fibroblasts; Humans; Infant, Newborn; Male | 1981 |
Molecular weight differences between human platelet and placental monoamine oxidase.
Topics: Blood Platelets; Electrophoresis, Polyacrylamide Gel; Female; Humans; In Vitro Techniques; Kinetics; | 1980 |
[Experimental studies of intra-amniotic pargyline and/or reserpine for termination of midterm pregnancy (author's transl)].
Topics: Abortion, Induced; Amnion; Animals; Female; Pargyline; Pregnancy; Pregnancy Trimester, Second; Rabbi | 1980 |
Fetal mesencephalic grafts influence the dopamine release in the non-lesioned striatum of 6-OHDA-lesioned rats: a behavioral and in vivo voltammetric study.
Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Brain Tissue Transplantation; Dopamine; Electro | 1994 |
Human anti-mitochondria autoantibodies appearing in iproniazid-induced immunoallergic hepatitis recognize human liver monoamine oxidase B.
Topics: Antibody Specificity; Antigen-Antibody Reactions; Autoantibodies; Chemical and Drug Induced Liver In | 1996 |
Na+-K+-ATPase activity in the brain cortex of rats ontogenetically malnourished, and treated with serotonin precursors.
Topics: 5-Hydroxytryptophan; Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Enzyme Activation; | 1979 |
Behavioral and prolactin responses to 5-hydroxytryptophan in rats treated during development with 5,7-dihydroxytryptamine.
Topics: 5-Hydroxytryptophan; 5,7-Dihydroxytryptamine; Animals; Animals, Newborn; Behavior, Animal; Benserazi | 1978 |
Effects of psychotrophic drugs on brain differentiation in female rats.
Topics: Aging; Animals; Animals, Newborn; Brain; Cell Differentiation; Estrus; Female; Male; Pargyline; Preg | 1977 |
Pre- and postnatal development of noradrenergic projections to the rat spinal cord: an immunocytochemical study.
Topics: Aging; Animals; Embryonic and Fetal Development; Female; Gestational Age; Immunohistochemistry; Moto | 1992 |
Dopaminergic and serotonergic activity in the hypothalamus during early and late pregnancy.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Amines; Dopamine; Female; Hydroxyindoleacetic Acid | 1991 |
Serotonin receptor activation of phosphoinositide turnover in uterine, fundal, vascular, and tracheal smooth muscle.
Topics: Animals; Aorta, Thoracic; Ergolines; Female; Gastric Fundus; Guinea Pigs; In Vitro Techniques; Muscl | 1987 |
Aromatase inhibition and experimental antitumor activity of FCE 24304, MDL 18962 and SH 489.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Androstadienes; Androstenedione; Animals; Antineoplastic Agents; A | 1989 |
[The formation of catecholaminergic structures in the mediobasal hypothalamus of the rat].
Topics: Animals; Catecholamines; Female; Glyoxylates; Histological Techniques; Hypothalamus, Middle; Microsc | 1989 |
Metabolic changes in glutathione and metallothionein in newborn rat liver.
Topics: Alkynes; Animals; Animals, Newborn; Buthionine Sulfoximine; Cysteine; Female; gamma-Glutamyltransfer | 1989 |
Characterization and quantitation of monoamine oxidases A and B in mitochondria from human placenta.
Topics: Binding Sites; Female; Humans; Immunoblotting; Mitochondria; Monoamine Oxidase; Pargyline; Phenethyl | 1989 |
Human trophoblast xenografts in athymic mice: a model for peripheral aromatization.
Topics: Androstenedione; Animals; Aromatase Inhibitors; Choriocarcinoma; Female; Humans; Mice; Mice, Inbred | 1989 |
Characterization of MAO A and MAO B in human placental mitochondria by activity, immunoblotting and radioimmunoassay with monoclonal antibodies and active site labeling with 3H-pargyline.
Topics: Antibodies, Monoclonal; Binding Sites; Female; Humans; Immunoblotting; In Vitro Techniques; Mitochon | 1988 |
Characterization of pregnant mare's serum gonadotropin-stimulated rat ovarian aromatase and its inhibition by 10-propargylestr-4-ene-3,17-dione.
Topics: Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Female; Gonadotropins, Equine; Humans; Ki | 1988 |
Studies on the mechanism of action of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Culture Techniques; Female; Kinetics; Monoami | 1985 |
Prevention of serotonin abortion by serotonin antagonists in rats.
Topics: Abortion, Induced; Animals; Atropine; Benzocycloheptenes; Dimethylamines; Ergolines; Female; Gestati | 1973 |
Fetal outcome from prolonged versus acute drug administration in the pregnant rat.
Topics: Abnormalities, Drug-Induced; Aminopropionitrile; Animals; Cleft Palate; Collagen; Demyelinating Dise | 1972 |
5-Hydroxytryptamine and sexual behavior in the female rat.
Topics: Amino Acids; Animals; Apomorphine; Castration; Circadian Rhythm; Electroshock; Estrus; Exploratory B | 1974 |
Serotonin deficiency in experimental hyperphenylalaninemia.
Topics: 5-Hydroxytryptophan; Animals; Biphenyl Compounds; Brain; Carbon Radioisotopes; Carboxy-Lyases; Dopa | 1974 |
The use of antiserotonin-cyproheptadine HCL in pregnancy: an experimental and clinical study.
Topics: Abortion, Habitual; Abortion, Spontaneous; Animals; Cyproheptadine; Female; Fetus; Humans; Hydroxyin | 1972 |
Proceedings: Recurrent pheochromocytoma.
Topics: Abdominal Neoplasms; Adolescent; Adrenal Gland Neoplasms; Adult; Child; Epinephrine; Female; Hormone | 1974 |
Effects of methadone on the action of catecholamines in isolated preparations.
Topics: Acetylcholine; Animals; Barium; Cats; Cocaine; Drug Antagonism; Drug Synergism; Epinephrine; Female; | 1971 |
Effect of reserpine on plasma LH levels in ovariectomized and cycling proestrus rats.
Topics: Animals; Castration; Estrus; Female; Hypothalamo-Hypophyseal System; Luteinizing Hormone; Monoamine | 1971 |
Monoamines and ovulation in the rat.
Topics: 5-Hydroxytryptophan; Animals; Animals, Newborn; Brain; Catecholamines; Depression, Chemical; Dihydro | 1968 |
Monoamines and hormone activated oestrous behaviour in the ovariectomized hamster.
Topics: 5-Hydroxytryptophan; Animals; Biogenic Amines; Brain; Castration; Cricetinae; Depression, Chemical; | 1970 |
The effect of pilocarpine in combination with monoamine oxidase inhibitors, imipramine or desmethylimipramine on oestrous behaviour in female rats.
Topics: Amines; Animals; Body Temperature; Castration; Central Nervous System; Desipramine; Drug Synergism; | 1970 |
Serotonin synthesis inhibition and estrous behavior in female rats.
Topics: Animals; Brain Chemistry; Castration; Dopamine; Estradiol; Estrus; Female; Pargyline; Phenylalanine; | 1970 |
Effect of cyproheptadiae (periactin) on accumulation of (14C)5-hydroxytryptamine in pregnant rats.
Topics: Animals; Carbon Isotopes; Cyproheptadine; Drug Synergism; Female; Fetus; Injections, Subcutaneous; M | 1971 |
Relationship between hypothalamic norepinephrine and serotonin and gonadotrophin secretion in the hamster.
Topics: Animals; Cricetinae; Estrus; Female; Gonadotropins; Hypothalamus; Methyltyrosines; Norepinephrine; O | 1968 |
Prevention of serotonin abortion in pregnant rats by five serotonin antagonists.
Topics: Abortion, Habitual; Abortion, Spontaneous; Anilides; Animals; Cyproheptadine; Ergolines; Female; Fet | 1969 |
Accumulation of [14C]5-hydroxytryptamine in the pregnant rat uterus after treatment with a monoamine oxidase inhibitor.
Topics: Animals; Carbon Isotopes; Estrogens; Female; Fetus; Pargyline; Pregnancy; Progesterone; Rats; Seroto | 1969 |
The significance of mono-amine oxidase in amniotic fluid in human foetal development.
Topics: Abortion, Therapeutic; Adult; Amniotic Fluid; Female; Fetus; Humans; Injections; Monoamine Oxidase; | 1965 |
Induction of legal abortion by intra-uterine instillation of pargyline hydrochloride (eutonyl).
Topics: Abortion, Legal; Adult; Female; Humans; Pargyline; Pregnancy | 1966 |