pargyline has been researched along with Pheochromocytoma in 4 studies
Pargyline: A monoamine oxidase inhibitor with antihypertensive properties.
Pheochromocytoma: A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The toxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), 1-methyl-4-(2'-ethylphenyl)-1,2,3,6-tetrahydropyridine (2'Et-MPTP), and their corresponding pyridinium species was studied in the rat pheochromocytoma PC12 cell line." | 3.68 | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine- and 1-methyl-4-(2'-ethylphenyl)-1,2,3,6-tetrahydropyridine-induced toxicity in PC12 cells: role of monoamine oxidase A. ( Basma, AN; Geller, HM; Giovanni, A; Heikkila, RE; Nicklas, WJ, 1990) |
| "Cells prepared from a transplantable rat pheochromocytoma synthesize norepinephrine from 14C-tyrosine, at a rate of 9." | 3.65 | Regulation of catecholamine biosynthesis in a transplantable rat pheochromocytoma. ( Chalfie, M; Perlman, RL, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chalfie, M | 1 |
| Perlman, RL | 1 |
| Basma, AN | 1 |
| Heikkila, RE | 1 |
| Nicklas, WJ | 1 |
| Giovanni, A | 1 |
| Geller, HM | 1 |
| Wagner, JA | 1 |
| Harrison, TS | 1 |
| Freier, DT | 1 |
| Cohen, EL | 1 |
4 other studies available for pargyline and Pheochromocytoma
| Article | Year |
|---|---|
Regulation of catecholamine biosynthesis in a transplantable rat pheochromocytoma.
Topics: Animals; Brocresine; Calcium; Cells, Cultured; Chromaffin System; Cycloheximide; Dihydroxyphenylalan | 1977 |
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine- and 1-methyl-4-(2'-ethylphenyl)-1,2,3,6-tetrahydropyridine-induced toxicity in PC12 cells: role of monoamine oxidase A.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adrenal Gland Neoplasms; Animals; Cell Survival; Clorg | 1990 |
Structure of catecholamine secretory vesicles from PC12 cells.
Topics: Adrenal Gland Neoplasms; Animals; Catecholamines; Cell Line; Centrifugation, Density Gradient; Cytop | 1985 |
Proceedings: Recurrent pheochromocytoma.
Topics: Abdominal Neoplasms; Adolescent; Adrenal Gland Neoplasms; Adult; Child; Epinephrine; Female; Hormone | 1974 |