pargyline has been researched along with Osteoarthritis in 1 studies
Pargyline: A monoamine oxidase inhibitor with antihypertensive properties.
Osteoarthritis: A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with tranylcypromine and pargyline, which are potent inhibitors of LSD1, prevented IL-1β-induced H3K9 demethylation at the mPGES-1 promoter and expression of mPGES-1." | 1.40 | Lysine-specific demethylase 1-mediated demethylation of histone H3 lysine 9 contributes to interleukin 1β-induced microsomal prostaglandin E synthase 1 expression in human osteoarthritic chondrocytes. ( Afif, H; Benderdour, M; El Mansouri, FE; Fahmi, H; Kapoor, M; Martel-Pelletier, J; Nebbaki, SS; Pelletier, JP, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| El Mansouri, FE | 1 |
| Nebbaki, SS | 1 |
| Kapoor, M | 1 |
| Afif, H | 1 |
| Martel-Pelletier, J | 1 |
| Pelletier, JP | 1 |
| Benderdour, M | 1 |
| Fahmi, H | 1 |
1 other study available for pargyline and Osteoarthritis
| Article | Year |
|---|---|
Lysine-specific demethylase 1-mediated demethylation of histone H3 lysine 9 contributes to interleukin 1β-induced microsomal prostaglandin E synthase 1 expression in human osteoarthritic chondrocytes.
Topics: Adult; Aged; Aged, 80 and over; Blotting, Western; Cells, Cultured; Chondrocytes; Gene Expression; H | 2014 |