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pargyline and Nerve Degeneration

pargyline has been researched along with Nerve Degeneration in 11 studies

Pargyline: A monoamine oxidase inhibitor with antihypertensive properties.

Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.

Research Excerpts

ExcerptRelevanceReference
"In pargyline treated rats, 17 h after denervation, noradrenaline stores were 90% of control glands."5.26Electron microscopic evidence that bretylium and pargyline delay adrenergic nerve degeneration after sympathectomy of the pineal gland. ( Gomez-Dumm, GL; Perec, CJ; Sanz, NR; Stefano, FJ, 1982)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19909 (81.82)18.7374
1990's1 (9.09)18.2507
2000's1 (9.09)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sanz, NR1
Gomez-Dumm, GL1
Perec, CJ3
Stefano, FJ3
Arbilla, S2
Lipska, BK1
Chrapusta, SJ1
Egan, MF1
Weinberger, DR1
Andringa, G1
van Oosten, RV1
Unger, W1
Hafmans, TG1
Veening, J1
Stoof, JC1
Cools, AR1
Hedreen, J1
Holzwarth-McBride, MA1
Sladek, JR1
Knigge, KM1
Butcher, LL1
Luthman, J1
Jonsson, G1
Clineschmidt, BV1
Sims, KL1
Bloom, FE1

Other Studies

11 other studies available for pargyline and Nerve Degeneration

ArticleYear
Electron microscopic evidence that bretylium and pargyline delay adrenergic nerve degeneration after sympathectomy of the pineal gland.
    Naunyn-Schmiedeberg's archives of pharmacology, 1982, Volume: 319, Issue:2

    Topics: Adrenergic Fibers; Animals; Bretylium Compounds; Female; Microscopy, Electron; Nerve Degeneration; N

1982
Delay by bretylium of adrenergic nerve degeneration after sympathectomy of the submaxillary gland.
    European journal of pharmacology, 1980, Jan-25, Volume: 61, Issue:2

    Topics: Animals; Bretylium Compounds; Dose-Response Relationship, Drug; Drug Interactions; Female; Metaramin

1980
Neonatal excitotoxic ventral hippocampal damage alters dopamine response to mild repeated stress and to chronic haloperidol.
    Synapse (New York, N.Y.), 1995, Volume: 20, Issue:2

    Topics: Animals; Corpus Striatum; Dopamine; Female; Frontal Lobe; Haloperidol; Handling, Psychological; Hipp

1995
Systemic administration of the propargylamine CGP 3466B prevents behavioural and morphological deficits in rats with 6-hydroxydopamine-induced lesions in the substantia nigra.
    The European journal of neuroscience, 2000, Volume: 12, Issue:8

    Topics: Animals; Antibodies; Apoptosis; Behavior, Animal; Body Weight; Denervation; Dopamine; Exploratory Be

2000
Neuronal degeneration caused by lateral ventricular injection of 6-hydroxy-dopamine. I. The ventral premammillary nucleus and other cell groups.
    Brain research, 1978, Nov-17, Volume: 157, Issue:1

    Topics: Animals; Axonal Transport; Cerebral Aqueduct; Hydroxydopamines; Hypothalamus, Middle; Injections, In

1978
Delay in nerve degeneration after sympathectomy of the submaxillary gland of the rat by treatment with pargyline, nialamide or beta-TM-10.
    The Journal of pharmacology and experimental therapeutics, 1977, Volume: 202, Issue:3

    Topics: Animals; Choline; Female; In Vitro Techniques; Metaraminol; Monoamine Oxidase; Nerve Degeneration; N

1977
Monosodium glutamate induced lesions of the arcurate nucleus. II. Fluorescence histochemistry of catecholamines.
    The Anatomical record, 1976, Volume: 186, Issue:2

    Topics: Animals; Catecholamines; Female; Fluorescence; Histocytochemistry; Hypothalamus; Hypothalamus, Anter

1976
Degenerative processes after punctate intracerebral administration of 6-hydroxydopamine.
    Journal of neural transmission, 1975, Volume: 37, Issue:3

    Topics: Acetylcholinesterase; Animals; Brain; Dihydrolipoamide Dehydrogenase; Drug Synergism; Female; Hydrox

1975
Effects of the parkinsonism-inducing neurotoxin MPTP and its metabolite MPP+ on sympathetic adrenergic nerves in mouse iris and atrium.
    Medical biology, 1986, Volume: 64, Issue:2-3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Adrenergic Fibers; Animal

1986
Spinal monoamines and the toxic interaction between monoamine oxidase inhibitors and tricyclic antidepressants.
    European journal of pharmacology, 1972, Volume: 19, Issue:1

    Topics: Animals; Antidepressive Agents; Cats; Drug Interactions; Female; Hydrazines; Imipramine; Male; Monoa

1972
Rat brain L-3,4-dihydroxyphenylalanine and L-5-hydroxytryptophan decarboxylase activities: differential effect of 6-hydroxydopamine.
    Brain research, 1973, Jan-15, Volume: 49, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Brain Stem; Carboxy-Lyases; Catecholamines; Cerebellum; Cerebral Corte

1973