pargyline has been researched along with MPTP Neurotoxicity Syndrome in 9 studies
Pargyline: A monoamine oxidase inhibitor with antihypertensive properties.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pretreatment with pargyline, a monoamine oxidase inhibitor, did not alter the mortality but prevented dopamine depletion." | 1.28 | Effects of internal carotid administration of MPTP on rat brain and blood-brain barrier. ( Dietrich, WD; Harik, SI; Riachi, NJ, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (66.67) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bazzu, G | 1 |
| Rocchitta, G | 1 |
| Migheli, R | 1 |
| Alvau, MD | 1 |
| Zinellu, M | 1 |
| Puggioni, G | 1 |
| Calia, G | 1 |
| Mercanti, G | 1 |
| Giusti, P | 1 |
| Desole, MS | 1 |
| Serra, PA | 1 |
| Andringa, G | 1 |
| Eshuis, S | 1 |
| Perentes, E | 1 |
| Maguire, RP | 1 |
| Roth, D | 1 |
| Ibrahim, M | 1 |
| Leenders, KL | 1 |
| Cools, AR | 1 |
| Watanabe, H | 1 |
| Muramatsu, Y | 1 |
| Kurosaki, R | 1 |
| Michimata, M | 1 |
| Matsubara, M | 1 |
| Imai, Y | 1 |
| Araki, T | 1 |
| Lai, M | 1 |
| Griffiths, H | 1 |
| Pall, H | 1 |
| Williams, A | 1 |
| Lunec, J | 1 |
| Takada, M | 1 |
| Sugimoto, T | 1 |
| Hattori, T | 1 |
| Kohutnicka, M | 1 |
| Lewandowska, E | 1 |
| Kurkowska-Jastrzebska, I | 1 |
| Członkowski, A | 1 |
| Członkowska, A | 1 |
| Riachi, NJ | 2 |
| Behmand, RA | 1 |
| Harik, SI | 2 |
| Pai, KS | 1 |
| Ravindranath, V | 1 |
| Dietrich, WD | 1 |
9 other studies available for pargyline and MPTP Neurotoxicity Syndrome
| Article | Year |
|---|---|
Effects of the neurotoxin MPTP and pargyline protection on extracellular energy metabolites and dopamine levels in the striatum of freely moving rats.
Topics: Animals; Corpus Striatum; Dopamine; Energy Metabolism; Male; Monoamine Oxidase Inhibitors; MPTP Pois | 2013 |
TCH346 prevents motor symptoms and loss of striatal FDOPA uptake in bilaterally MPTP-treated primates.
Topics: Animals; Corpus Striatum; Dihydroxyphenylalanine; Macaca mulatta; Male; Motor Skills Disorders; MPTP | 2003 |
Protective effects of neuronal nitric oxide synthase inhibitor in mouse brain against MPTP neurotoxicity: an immunohistological study.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transpo | 2004 |
An investigation into the role of reactive oxygen species in the mechanism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity using neuronal cell lines.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Catalase; Cell D | 1993 |
MPTP neurotoxicity to cerebellar Purkinje cells in mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Benztropine; Dose-Response Relationship, Drug | 1993 |
Microglial and astrocytic involvement in a murine model of Parkinson's disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Astrocytes; Disease Models, Animal; Dopamine; | 1998 |
Correlation of MPTP neurotoxicity in vivo with oxidation of MPTP by the brain and blood-brain barrier in vitro in five rat strains.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Behavior, Animal; Biogenic Amines; Blood-Brai | 1991 |
Protection and potentiation of MPTP-induced toxicity by cytochrome P-450 inhibitors and inducer: in vitro studies with brain slices.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Cytochrome P-450 Enzyme Inhibitors; Cy | 1991 |
Effects of internal carotid administration of MPTP on rat brain and blood-brain barrier.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Aminoisobutyric Acids; Animals; Biogenic Monoamines; B | 1990 |