pargyline and Interstitial Cell Tumor studies

pargyline and Interstitial Cell Tumor

Pargyline: A monoamine oxidase inhibitor with antihypertensive properties.

Research Excerpts

Excerpt	Relevance	Reference
"The murine Leydig cell tumor (M5480A) possesses high levels of estrogen receptor and is known to produce estrogens."	1.28	Effect of 4-hydroxyandrostenedione on murine Leydig tumor cell steroidogenesis. ( Brandt, ME; Brodie, AM; Melner, MH; Puett, D; Zimniski, SJ, 1991)
"The murine Leydig cell tumor (M5480A) was assayed for the presence of aromatase activity and for the effects of 10-propargylestr-4-ene-3,17-dione (PED), an aromatase inhibitor, on steroidogenesis."	1.27	Inhibition of Leydig tumor cell steroidogenesis by 10-propargylestr-4-ene-3,17-dione, an irreversible aromatase inhibitor. ( Brandt, ME; Covey, DF; Melner, MH; Puett, D; Zimniski, SJ, 1985)

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (33.33)	18.7374
1990's	2 (66.67)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

1 (33.33)

18.7374

1990's

2 (66.67)

18.2507

2000's

0 (0.00)

29.6817

2010's

0 (0.00)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Doody, KM	1
Murry, BA	1
Mason, JI	1
Zimniski, SJ	2
Brandt, ME	2
Melner, MH	2
Brodie, AM	1
Puett, D	2
Covey, DF	1

Studies

Doody, KM

Murry, BA

Mason, JI

Zimniski, SJ

Brandt, ME

Melner, MH

Brodie, AM

Puett, D

Covey, DF

Other Studies

3 other studies available for pargyline and Interstitial Cell Tumor

Article	Year
The use of rat Leydig tumor (R2C) and human hepatoma (HEPG2) cells to evaluate potential inhibitors of rat and human steroid aromatase. Journal of enzyme inhibition, 1990, Volume: 4, Issue:2 Topics: Androstenedione; Animals; Antineoplastic Agents; Aromatase Inhibitors; Carcinoma, Hepatocellular; Ce	1990
Effect of 4-hydroxyandrostenedione on murine Leydig tumor cell steroidogenesis. Cancer research, 1991, Jul-15, Volume: 51, Issue:14 Topics: Androstenedione; Animals; Aromatase Inhibitors; Leydig Cell Tumor; Male; Mice; Pargyline; Pregnenolo	1991
Inhibition of Leydig tumor cell steroidogenesis by 10-propargylestr-4-ene-3,17-dione, an irreversible aromatase inhibitor. Cancer research, 1985, Volume: 45, Issue:10 Topics: Androstenedione; Animals; Aromatase Inhibitors; Leydig Cell Tumor; Male; Mice; Mice, Inbred C57BL; O	1985

Article

Year

The use of rat Leydig tumor (R2C) and human hepatoma (HEPG2) cells to evaluate potential inhibitors of rat and human steroid aromatase.

Journal of enzyme inhibition, 1990, Volume: 4, Issue:2

Topics: Androstenedione; Animals; Antineoplastic Agents; Aromatase Inhibitors; Carcinoma, Hepatocellular; Ce

1990

Effect of 4-hydroxyandrostenedione on murine Leydig tumor cell steroidogenesis.

Cancer research, 1991, Jul-15, Volume: 51, Issue:14

Topics: Androstenedione; Animals; Aromatase Inhibitors; Leydig Cell Tumor; Male; Mice; Pargyline; Pregnenolo

1991

Inhibition of Leydig tumor cell steroidogenesis by 10-propargylestr-4-ene-3,17-dione, an irreversible aromatase inhibitor.

Cancer research, 1985, Volume: 45, Issue:10

Topics: Androstenedione; Animals; Aromatase Inhibitors; Leydig Cell Tumor; Male; Mice; Mice, Inbred C57BL; O

1985