pargyline has been researched along with Disease Models, Animal in 23 studies
Pargyline: A monoamine oxidase inhibitor with antihypertensive properties.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Both paroxetine and pargyline were effective in reducing the immobility time of stressed OVX mice in the FST." | 1.38 | Effects of diphenyl diselenide on depressive-like behavior in ovariectomized mice submitted to subchronic stress: involvement of the serotonergic system. ( Bazanella Sampaio, T; Mozzaquatro Gai, B; Nogueira, CW; Pinton, S; Trevisan da Rocha, J; Zeni, G, 2012) |
| "Pretreatment with pargyline attenuated the MPTP-induced clinical signs, MRI and MRS changes, and the histopathological and immunoreactivity alterations." | 1.32 | Proton magnetic resonance imaging and spectroscopy identify metabolic changes in the striatum in the MPTP feline model of parkinsonism. ( Hadjiconstantinou, M; Neff, NH; Podell, M; Smith, MA, 2003) |
| "Experimental allergic encephalomyelitis (EAE), a T cell-mediated autoimmune disease can be transferred with lymphoid cells from actively immunized rats into naive recipients." | 1.28 | The role of mast cells in the elicitation of experimental allergic encephalomyelitis. ( Dietsch, GN; Hinrichs, DJ, 1989) |
| "Indoleamine-induced myoclonus in guinea pigs is a specific model of brainstem 5-HT function that can be used to characterize the indoleamine systems initiating myoclonus." | 1.27 | 5-HT-mediated myoclonus in the guinea pig as a model of brainstem 5-HT and tryptamine receptor action. ( Jenner, P; Luscombe, G; Marsden, CD, 1986) |
| " Chronic administration of imipramine-HCl (1 and 5 mg/kg, i." | 1.27 | Effects of antidepressant drugs on a quickly-learned conditioned-suppression response in mice. ( Kameyama, T; Nagasaka, M; Yamada, K, 1985) |
| "0 mg/kg) attenuated, in a dose-response fashion, the induction of stereotyped behavior and hyperactivity by pargyline (0." | 1.26 | Testosterone-attenuated stereotype and hyperactivity induced by beta-phenylethylamine in pargyline-pretreated rats. ( Freemark, M; Gillin, JC; Moja, EA; Stoff, DM; Wyatt, RJ, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (47.83) | 18.7374 |
| 1990's | 3 (13.04) | 18.2507 |
| 2000's | 2 (8.70) | 29.6817 |
| 2010's | 4 (17.39) | 24.3611 |
| 2020's | 3 (13.04) | 2.80 |
| Authors | Studies |
|---|---|
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Jiang, X | 2 |
| Guo, J | 2 |
| Lv, Y | 1 |
| Yao, C | 2 |
| Zhang, C | 2 |
| Mi, Z | 1 |
| Shi, Y | 1 |
| Gu, J | 1 |
| Zhou, T | 2 |
| Bai, R | 2 |
| Xie, Y | 2 |
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Zhang, Y | 1 |
| Zhang, J | 1 |
| Zhong, Z | 1 |
| Ge, J | 1 |
| Baranyi, M | 1 |
| Porceddu, PF | 1 |
| Gölöncsér, F | 1 |
| Kulcsár, S | 1 |
| Otrokocsi, L | 1 |
| Kittel, Á | 1 |
| Pinna, A | 1 |
| Frau, L | 1 |
| Huleatt, PB | 1 |
| Khoo, ML | 1 |
| Chai, CL | 1 |
| Dunkel, P | 1 |
| Mátyus, P | 1 |
| Morelli, M | 1 |
| Sperlágh, B | 1 |
| Chaaya, R | 1 |
| Alfarano, C | 1 |
| Guilbeau-Frugier, C | 1 |
| Coatrieux, C | 1 |
| Kesteman, AS | 1 |
| Parini, A | 1 |
| Fares, N | 1 |
| Gue, M | 1 |
| Schanstra, JP | 1 |
| Bascands, JL | 1 |
| Trevisan da Rocha, J | 1 |
| Mozzaquatro Gai, B | 1 |
| Pinton, S | 1 |
| Bazanella Sampaio, T | 1 |
| Nogueira, CW | 1 |
| Zeni, G | 1 |
| Podell, M | 1 |
| Hadjiconstantinou, M | 1 |
| Smith, MA | 1 |
| Neff, NH | 1 |
| Bhadra, S | 1 |
| Prather, PL | 1 |
| Elkhayat, I | 1 |
| Benjamin, D | 1 |
| Harris, CM | 1 |
| Lal, H | 1 |
| Zimniski, SJ | 1 |
| Brandt, ME | 1 |
| Covey, DF | 1 |
| Puett, D | 1 |
| Kohutnicka, M | 1 |
| Lewandowska, E | 1 |
| Kurkowska-Jastrzebska, I | 1 |
| Członkowski, A | 1 |
| Członkowska, A | 1 |
| Andringa, G | 1 |
| Cools, AR | 1 |
| Freemark, M | 1 |
| Stoff, DM | 2 |
| Moja, EA | 2 |
| Gillin, JC | 2 |
| Wyatt, RJ | 2 |
| Gross, S | 1 |
| Coleman, M | 1 |
| Randall, J | 1 |
| Luscombe, G | 1 |
| Jenner, P | 2 |
| Marsden, CD | 2 |
| Dietsch, GN | 1 |
| Hinrichs, DJ | 1 |
| Barbeau, A | 1 |
| Dallaire, L | 1 |
| Buu, NT | 1 |
| Veilleux, F | 1 |
| Boyer, H | 1 |
| de Lanney, LE | 1 |
| Irwin, I | 1 |
| Langston, EB | 1 |
| Langston, JW | 1 |
| Kameyama, T | 1 |
| Nagasaka, M | 1 |
| Yamada, K | 1 |
| Yu, MK | 1 |
| Wright, TL | 1 |
| Dettbarn, WD | 1 |
| Olson, WH | 1 |
| Plotnikoff, NP | 1 |
| Kastin, AJ | 1 |
| Anderson, MS | 1 |
| Schally, AV | 1 |
| Hunt, WA | 1 |
| Majchrowicz, E | 1 |
1 review available for pargyline and Disease Models, Animal
| Article | Year |
|---|---|
The actions of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in animals as a model of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzaze | 1986 |
22 other studies available for pargyline and Disease Models, Animal
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Rational design, synthesis and biological evaluation of novel multitargeting anti-AD iron chelators with potent MAO-B inhibitory and antioxidant activity.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Behavior, Animal; Binding Sites; Ce | 2020 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
N-Propargylamine-hydroxypyridinone hybrids as multitarget agents for the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Blood-Brain Barrier; Disease Models, Animal; Drug Design; Drug Stability | 2021 |
Novel (Hetero)arylalkenyl propargylamine compounds are protective in toxin-induced models of Parkinson's disease.
Topics: Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Male; Oxidative St | 2016 |
Pargyline reduces renal damage associated with ischaemia-reperfusion and cyclosporin.
Topics: Animals; Cyclosporine; Disease Models, Animal; Immunosuppressive Agents; Kidney; Kidney Diseases; Ma | 2011 |
Effects of diphenyl diselenide on depressive-like behavior in ovariectomized mice submitted to subchronic stress: involvement of the serotonergic system.
Topics: Animals; Antidepressive Agents; Benzene Derivatives; Cerebral Cortex; Depression; Disease Models, An | 2012 |
Proton magnetic resonance imaging and spectroscopy identify metabolic changes in the striatum in the MPTP feline model of parkinsonism.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Aspartic Acid; Brain; Cats; Choline; Corpus S | 2003 |
Anxiogenic effect of disulfiram evaluated in an animal model.
Topics: Acetaldehyde; Animals; Appetitive Behavior; Arousal; Conditioning, Operant; Discrimination Learning; | 1993 |
Inhibition of growth and appearance of estrogen-dependent rat mammary tumors by 10-propargylestr-4-ene-3,17-dione, an aromatase inhibitor.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Androstenedione; Animals; Antineoplastic Agents; Aromatase Inhibit | 1993 |
Microglial and astrocytic involvement in a murine model of Parkinson's disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Astrocytes; Disease Models, Animal; Dopamine; | 1998 |
The neuroprotective effects of CGP 3466B in the best in vivo model of Parkinson's disease, the bilaterally MPTP-treated rhesus monkey.
Topics: Animals; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Macaca mulatta; Male; Neur | 2000 |
Testosterone-attenuated stereotype and hyperactivity induced by beta-phenylethylamine in pargyline-pretreated rats.
Topics: Animals; Behavior; Disease Models, Animal; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induce | 1978 |
Disruption of conditioned avoidance behavior by n,n-dimethyltryptamine (DMT) and stereotype by beta-phenylethylamine (PEA): animal models of attentional defects in schizophrenia.
Topics: Animals; Attention; Avoidance Learning; Behavior; Chlorpromazine; Conditioning, Operant; Disease Mod | 1978 |
Pargyline-induced myopathy in rats and vitamin B6.
Topics: Animals; Disease Models, Animal; Female; Magnesium; Muscles; Muscular Diseases; Pargyline; Pyridoxin | 1975 |
5-HT-mediated myoclonus in the guinea pig as a model of brainstem 5-HT and tryptamine receptor action.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Brain; Carbidopa; Disease Models, Animal; Guinea Pig | 1986 |
The role of mast cells in the elicitation of experimental allergic encephalomyelitis.
Topics: Animals; Chromones; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Hyp | 1989 |
New amphibian models for the study of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Brain Chemistry; | 1985 |
Effects of antidepressant drugs on a quickly-learned conditioned-suppression response in mice.
Topics: Acridines; Amitriptyline; Animals; Antidepressive Agents; Depressive Disorder; Desipramine; Diphenhy | 1985 |
Pargyline-induced myopathy with histochemical characteristics of Duchenne muscular dystrophy.
Topics: Acetylcholine; Adenosine Triphosphatases; Animals; Aorta, Abdominal; Biogenic Amines; Disease Models | 1974 |
Deserpidine antagonism by a tripeptide, L-prolyl-L-leucyglycinamide.
Topics: Animals; Depression; Dihydroxyphenylalanine; Disease Models, Animal; Dose-Response Relationship, Dru | 1973 |
Turnover rates and steady-state levels of brain serotonin in alcohol-dependent rats.
Topics: Alcoholic Intoxication; Alcoholism; Animals; Brain; Chromatography, Gas; Disease Models, Animal; Eth | 1974 |