pargyline has been researched along with Choriocarcinoma in 2 studies
Pargyline: A monoamine oxidase inhibitor with antihypertensive properties.
Choriocarcinoma: A malignant metastatic form of trophoblastic tumors. Unlike the HYDATIDIFORM MOLE, choriocarcinoma contains no CHORIONIC VILLI but rather sheets of undifferentiated cytotrophoblasts and syncytiotrophoblasts (TROPHOBLASTS). It is characterized by the large amounts of CHORIONIC GONADOTROPIN produced. Tissue origins can be determined by DNA analyses: placental (fetal) origin or non-placental origin (CHORIOCARCINOMA, NON-GESTATIONAL).
| Excerpt | Relevance | Reference |
|---|---|---|
| " This model of peripheral aromatization was utilized to evaluate in vivo pharmacological parameters of MDL 18,962 (10-(2-propynyl)estr-4-ene-3,17-dione) such as bioavailability of several formulations, time course and dose responses following different routes of drug administration, pharmacokinetics and tissue distribution of [14C]MDL 18,962." | 1.28 | Human trophoblast xenografts in athymic mice: a model for peripheral aromatization. ( Johnston, JO; Shumaker, RC; Wright, CL, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Johnston, JO | 2 |
| Wright, CL | 2 |
| Metcalf, BW | 1 |
| Shumaker, RC | 1 |
2 other studies available for pargyline and Choriocarcinoma
| Article | Year |
|---|---|
Time-dependent inhibition of aromatase in trophoblastic tumor cells in tissue culture.
Topics: Androstenedione; Aromatase Inhibitors; Cell Line; Choriocarcinoma; Estrogens; Female; Humans; Kineti | 1984 |
Human trophoblast xenografts in athymic mice: a model for peripheral aromatization.
Topics: Androstenedione; Animals; Aromatase Inhibitors; Choriocarcinoma; Female; Humans; Mice; Mice, Inbred | 1989 |