Page last updated: 2024-11-02

pargyline and Breast Neoplasms

pargyline has been researched along with Breast Neoplasms in 8 studies

Pargyline: A monoamine oxidase inhibitor with antihypertensive properties.

Breast Neoplasms: Tumors or cancer of the human BREAST.

Research Excerpts

ExcerptRelevanceReference
" Among the steroid substrate analogs, 4-hydroxyandrostenedione has been shown to be effective in breast cancer patients with advanced disease and was recently approved for treatment in the United Kingdom."4.78Aromatase, its inhibitors and their use in breast cancer treatment. ( Brodie, AM, 1993)
"Treatment of ER-positive xenograft-based breast tumors with PELP1-siRNA-DOPC or pargyline reduced tumor volume by 58."1.38Targeting the PELP1-KDM1 axis as a potential therapeutic strategy for breast cancer. ( Cortez, V; Lopez-Berestein, G; Mann, M; Miyata, N; Rodriguez-Aguayo, C; Sood, AK; Suzuki, T; Tekmal, S; Vadlamudi, RK, 2012)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19903 (37.50)18.7374
1990's1 (12.50)18.2507
2000's0 (0.00)29.6817
2010's4 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bansode, P1
Anantacharya, R1
Dhanavade, M1
Kamble, S1
Barale, S1
Sonawane, K1
Satyanarayan, ND1
Rashinkar, G1
Pollock, JA1
Larrea, MD1
Jasper, JS1
McDonnell, DP1
McCafferty, DG1
Cortez, V1
Mann, M1
Tekmal, S1
Suzuki, T1
Miyata, N1
Rodriguez-Aguayo, C1
Lopez-Berestein, G1
Sood, AK1
Vadlamudi, RK1
Vasilatos, SN1
Katz, TA1
Oesterreich, S1
Wan, Y1
Davidson, NE1
Huang, Y1
MacIndoe, JH1
Woods, GR1
Etre, LA1
Covey, DF3
Perel, E1
Davis, SP1
Killinger, DW1
Brodie, AM1
Brandt, ME1
Puett, D1
Garola, R1
Fendl, K1
Zimniski, SJ1

Reviews

2 reviews available for pargyline and Breast Neoplasms

ArticleYear
Aromatase, its inhibitors and their use in breast cancer treatment.
    Pharmacology & therapeutics, 1993, Volume: 60, Issue:3

    Topics: Aminoglutethimide; Androstenedione; Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Breast N

1993
Aromatase and aromatase inhibitors: from enzymology to selective chemotherapy.
    Progress in clinical and biological research, 1988, Volume: 262

    Topics: Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Neoplas

1988

Other Studies

6 other studies available for pargyline and Breast Neoplasms

ArticleYear
Evaluation of drug candidature: In silico ADMET, binding interactions with CDK7 and normal cell line studies of potentially anti-breast cancer enamidines.
    Computational biology and chemistry, 2019, Volume: 83

    Topics: Amines; Animals; Antineoplastic Agents; Azides; Binding Sites; Breast Neoplasms; Cell Proliferation;

2019
Lysine-specific histone demethylase 1 inhibitors control breast cancer proliferation in ERĪ±-dependent and -independent manners.
    ACS chemical biology, 2012, Jul-20, Volume: 7, Issue:7

    Topics: Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Enzyme Inhibitors; Estrogen Receptor alpha;

2012
Targeting the PELP1-KDM1 axis as a potential therapeutic strategy for breast cancer.
    Breast cancer research : BCR, 2012, Jul-19, Volume: 14, Issue:4

    Topics: Animals; Benzamides; Breast Neoplasms; Carcinogens; Cell Line, Tumor; Cell Proliferation; Co-Repress

2012
Crosstalk between lysine-specific demethylase 1 (LSD1) and histone deacetylases mediates antineoplastic efficacy of HDAC inhibitors in human breast cancer cells.
    Carcinogenesis, 2013, Volume: 34, Issue:6

    Topics: Apoptosis; Apoptosis Regulatory Proteins; Breast Neoplasms; Cadherins; Cell Line, Tumor; Cell Prolif

2013
Comparative studies of aromatase inhibitors in cultured human breast cancer cells.
    Cancer research, 1982, Volume: 42, Issue:8 Suppl

    Topics: Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Cell Line; Dihydrotestos

1982
Effects of 4-hydroxy-4-androstene-3, 17-dione and 10-propargylestr-4-ene-3, 17-dione on the metabolism of androstenedione in human breast carcinoma and breast adipose tissues.
    Steroids, 1981, Volume: 38, Issue:4

    Topics: Adipose Tissue; Androstenedione; Breast; Breast Neoplasms; Female; Humans; Kinetics; Pargyline

1981