Page last updated: 2024-09-03

parecoxib and Inflammation

parecoxib has been researched along with Inflammation in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (17.65)29.6817
2010's10 (58.82)24.3611
2020's4 (23.53)2.80

Authors

AuthorsStudies
Heitel, P; Kalinowsky, L; Merk, D; Proschak, E1
Li, M; Zheng, Z1
Jin, X; Qin, J; Su, X; Zhao, J1
Chen, Q; Guo, Y; Min, S; Wu, B1
Huang, JM; Jiang, WX; Lv, ZT; Nie, MB; Zhang, B1
Chen, G; Ding, B; Duan, K; Li, X; Li, Y; Ouyang, W; Zhou, L1
Chen, J; Cong, X; Zhan, X; Zheng, W; Zhou, Z1
Wang, S; Wu, H; Wu, Y; Zhu, Y1
Cui, W; Yu, X; Zhang, H1
Chen, G; Li, X; Li, Y; Liang, H; Ouyang, W; Tong, J; Wu, Y; Zhou, L1
Li, P; Liu, Z; Yang, M; Yang, X1
Brack, A; Broscheit, JA; Rittner, HL; Roewer, N; Sauer, RS; Shityakov, S; Sohajda, T1
Herschman, HR; Ishikawa, TO; Jain, NK; Spigelman, I1
Avila, R; Cardenas, R; Quintero, L; Siso, A; Suarez-Roca, H; Urdaneta, A; Urdaneta, B1
Bosselmann, S; Chada, M; Gessner, A; Kandler, M; Nögel, SC; Rascher, W; Schmidt, AM; Schneider, H; Schweer, H; Watzer, B1
Mateos, JL1
Dong, N; Gui, P; Purusram, G; Wang, H; Wu, Q; Xie, W; Yao, S; Yuan, R1

Reviews

3 review(s) available for parecoxib and Inflammation

ArticleYear
Opportunities and Challenges for Fatty Acid Mimetics in Drug Discovery.
    Journal of medicinal chemistry, 2017, 07-13, Volume: 60, Issue:13

    Topics: Animals; Cyclooxygenase Inhibitors; Drug Discovery; Fatty Acids; Humans; Inflammation; Models, Molecular

2017
Intravenous parecoxib for early postoperative cognitive dysfunction in elderly patients: evidence from a meta-analysis.
    Expert review of clinical pharmacology, 2020, Volume: 13, Issue:4

    Topics: Aged; Animals; Asian People; Cyclooxygenase 2 Inhibitors; Humans; Inflammation; Isoxazoles; Postoperative Cognitive Complications; Randomized Controlled Trials as Topic

2020
[Selective inhibitors of cyclooxygenase-2 (COX-2), celecoxib and parecoxib: a systematic review].
    Drugs of today (Barcelona, Spain : 1998), 2010, Volume: 46 Suppl A

    Topics: Animals; Celecoxib; Cyclooxygenase 2 Inhibitors; Drug Administration Routes; Evidence-Based Medicine; Humans; Inflammation; Isoxazoles; Pain; Pain Measurement; Pyrazoles; Structure-Activity Relationship; Sulfonamides; Treatment Outcome

2010

Trials

4 trial(s) available for parecoxib and Inflammation

ArticleYear
[Parecoxib suppresses the increase of neutrophil-to-lymphocyte ratio after the modified radical mastectomy].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2017, Sep-28, Volume: 42, Issue:9

    Topics: Breast Neoplasms; Cyclooxygenase 2 Inhibitors; Female; Humans; Inflammation; Isoxazoles; Lymphocytes; Mastectomy; Neutrophils; Treatment Outcome

2017
Effect of perioperative parecoxib on postoperative pain and local inflammation factors PGE2 and IL-6 for total knee arthroplasty: a randomized, double-blind, placebo-controlled study.
    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2014, Volume: 24, Issue:3

    Topics: Aged; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Cyclooxygenase 2 Inhibitors; Dinoprostone; Double-Blind Method; Female; Humans; Inflammation; Interleukin-6; Isoxazoles; Knee Joint; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Postoperative Nausea and Vomiting; Range of Motion, Articular; Synovial Fluid

2014
Propranolol Attenuates Surgical Stress-Induced Elevation of the Regulatory T Cell Response in Patients Undergoing Radical Mastectomy.
    Journal of immunology (Baltimore, Md. : 1950), 2016, Apr-15, Volume: 196, Issue:8

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Breast Neoplasms; Catecholamines; Cell Proliferation; Cells, Cultured; Dinoprostone; Epinephrine; Female; Forkhead Transcription Factors; Humans; Immune Tolerance; Inflammation; Interferon-gamma; Isoxazoles; Leukocytes, Mononuclear; Lymphocyte Count; Mastectomy, Radical; Middle Aged; Norepinephrine; Propranolol; RNA, Messenger; Stress, Physiological; T-Lymphocytes, Regulatory

2016
The efficacy of parecoxib on systemic inflammatory response associated with cardiopulmonary bypass during cardiac surgery.
    British journal of clinical pharmacology, 2013, Volume: 75, Issue:3

    Topics: Adult; Biomarkers; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Creatine Kinase; Creatine Kinase, MB Form; Cyclooxygenase 2 Inhibitors; Cytokines; Enzyme-Linked Immunosorbent Assay; Female; Heart Valve Prosthesis Implantation; Humans; Inflammation; Isoxazoles; Leukocyte Count; Male; Middle Aged; Mitral Valve; Postoperative Complications; Treatment Outcome; Troponin T

2013

Other Studies

10 other study(ies) available for parecoxib and Inflammation

ArticleYear
Protective effect of parecoxib sodium against ischemia reperfusion‑induced intestinal injury.
    Molecular medicine reports, 2021, Volume: 24, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Cyclooxygenase 2 Inhibitors; Inflammation; Isoxazoles; Male; Malondialdehyde; Oxidative Stress; Peroxidase; Protective Agents; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction

2021
Parecoxib mitigates lung ischemia-reperfusion injury in rats by reducing oxidative stress and inflammation and up-regulating HO-1 expression.
    Acta cirurgica brasileira, 2021, Volume: 36, Issue:9

    Topics: Animals; Heme Oxygenase-1; Inflammation; Isoxazoles; Lung; Lung Injury; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reperfusion Injury

2021
Parecoxib ameliorates renal toxicity and injury in sepsis-induced mouse model and LPS-induced HK-2 cells.
    Drug development research, 2022, Volume: 83, Issue:3

    Topics: Acute Kidney Injury; Animals; Apoptosis; Cyclooxygenase 2; Disease Models, Animal; I-kappa B Kinase; Inflammation; Isoxazoles; Lipopolysaccharides; Mice; NF-kappa B; Sepsis

2022
Effects of Parecoxib on Pain Threshold and Inflammatory Factors IL-1β, IL-6 and TNF-
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2019, Volume: 29, Issue:6

    Topics: Animals; Bone Neoplasms; Cancer Pain; Cyclooxygenase 2 Inhibitors; Down-Regulation; Female; Hyperalgesia; Inflammation; Interleukin-1beta; Interleukin-6; Isoxazoles; Pain Threshold; Random Allocation; Rats; Rats, Sprague-Dawley; Spinal Cord; Tumor Necrosis Factor-alpha

2019
The Study of Different Approaches of Parecoxib Sodium Pretreatment on the Behavior of Rats with Neuropathic Pain.
    Cell biochemistry and biophysics, 2015, Volume: 72, Issue:1

    Topics: Analgesics; Animals; Disease Models, Animal; Drug Administration Schedule; Hot Temperature; Inflammation; Injections, Intraperitoneal; Injections, Spinal; Isoxazoles; Male; Neuralgia; Pain Management; Pain Measurement; Random Allocation; Rats; Rats, Sprague-Dawley; Spinal Nerves

2015
[Effect of parecoxib on hippocampal inflammation and memory function in aged rats after splenectomy].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2016, Jun-28, Volume: 41, Issue:6

    Topics: Animals; Cyclooxygenase 2; Hippocampus; Inflammation; Interleukin-1beta; Isoxazoles; Male; Memory; Rats; Rats, Sprague-Dawley; Splenectomy; Tumor Necrosis Factor-alpha

2016
A Novel Approach for the Control of Inflammatory Pain: Prostaglandin E2 Complexation by Randomly Methylated β-Cyclodextrins.
    Anesthesia and analgesia, 2017, Volume: 124, Issue:2

    Topics: Animals; beta-Cyclodextrins; Computer Simulation; Cyclooxygenase 2 Inhibitors; Dinoprostone; Electrophoresis, Capillary; Hyperalgesia; Inflammation; Inflammation Mediators; Isoxazoles; Male; Methylation; Pain; Pain Measurement; Pain Threshold; Postural Balance; Rats; Rats, Wistar

2017
COX-2 expression and function in the hyperalgesic response to paw inflammation in mice.
    Prostaglandins, leukotrienes, and essential fatty acids, 2008, Volume: 79, Issue:6

    Topics: Animals; Blotting, Western; Brain; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Disease Models, Animal; Edema; Gene Expression Regulation, Enzymologic; Hindlimb; Hyperalgesia; Inflammation; Isoxazoles; Mice; Mice, Inbred C57BL; Mice, Knockout; Reverse Transcriptase Polymerase Chain Reaction; Spinal Cord; Zymosan

2008
Lack of correlation between the central anti-nociceptive and peripheral anti-inflammatory effects of selective COX-2 inhibitor parecoxib.
    Brain research bulletin, 2009, Aug-28, Volume: 80, Issue:1-2

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Extremities; Inflammation; Isoenzymes; Isoxazoles; Ketoprofen; Male; Membrane Proteins; Rats; Rats, Sprague-Dawley

2009
Parecoxib does not suppress thromboxane synthesis in newborn piglets with group B streptococcal sepsis.
    Prostaglandins & other lipid mediators, 2009, Volume: 90, Issue:1-2

    Topics: Animals; Animals, Newborn; Cyclooxygenase 2 Inhibitors; Dinoprostone; Epoprostenol; Gene Expression Regulation; Hemodynamics; Indomethacin; Inflammation; Isoxazoles; Lung; Platelet Count; Receptors, Prostaglandin E; Sepsis; Streptococcal Infections; Streptococcus agalactiae; Swine; Thromboxanes

2009