Page last updated: 2024-08-21

paraquat and Parkinsonian Disorders

paraquat has been researched along with Parkinsonian Disorders in 65 studies

Research

Studies (65)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	18 (27.69)	29.6817
2010's	38 (58.46)	24.3611
2020's	9 (13.85)	2.80

Authors

Authors	Studies
Bagatini, PB; da Silva, RB; da Veiga, LC; de Miranda Monteiro, VAC; de Revoredo Ribeiro, EC; de Souza Silva, EL; Knijkik, GP; Mestriner, RG; Milanesi, BB; Neves, LT; Neves, PFR; Paz, LV; Sulzbach, JH; Vieira, MQ; Wieck, A; Xavier, LL	1
Cheng, Y; Deng, P; Duan, W; Fu, G; He, H; Hong, H; Lin, X; Lu, Y; Mao, G; Pi, H; Tong, T; Wang, X; Xu, J; Xu, S; Xu, Y; Yang, L; Yu, Z; Zhang, J; Zhou, Z	1
Bove, C; Coleman, FH; Travagli, RA	1
Ding, W; Hong, X; Ji, D; Lin, H; Wu, F	1
Hou, L; Huang, R; Qiu, X; Qu, X; Wang, Q; Zhao, X	1
Freeman, JL; Wasel, O	1
Ahmad, B; Akhtar, MF; Anwar, F; Ismail, T; Nazir, S; Saleem, U; Sanawar, M	1
Chen, YB; Cui, YL; Wang, YQ; Wu, JR	1
Baetu, I; Collins-Praino, LE; El-Gamal, M; Fathalla, AM; Mohamed, W; Moustafa, AA; Salama, M; Soliman, AM	1
Hou, L; Qiu, X; Wang, Q; Zhang, C; Zhao, X	1
Bianchini, MC; Denardin, ELG; Gallarreta, MS; Gayer, MC; Gonçalves, MB; Lemos, MC; Puntel, RL; Rodrigues, DT; Roehrs, R; Soares, JJ	1
He, D; Lei, L; Liu, M; Lou, D; Lu, S; Shi, Y; Song, Y; Wang, Z; Wu, S	1
Adeyemi, OO; Akataobi, OE; Alade, AA; Ishola, IO	1
Ivanets, EV; Menchinskaya, ES; Pislyagin, EA; Smetanina, OF; Trinh, PTH; Yurchenko, AN; Yurchenko, EA	1
Siedlak, SL; Tang, B; Torres, SL; Xu, Q; Zhao, F; Zhu, X	1
Hosamani, R; Krishna, G	1
Anselmi, L; Bove, C; Travagli, RA	1
Chouhan, S; Prakash, J; Singh, SP; Yadav, SK	2
Chauhan, AK; Jain, SK; Shanker, R; Singh, C; Singh, MP; Singhal, NK	1
Dagda, RK; Das Banerjee, T; Janda, E	1
Abdin, MZ; Chaouhan, HS; Chowdhuri, DK; Patel, DK; Pragya, P; Shukla, AK; Tiwari, AK	1
Cao, X; Gao, T; Li, X; Lin, L; Liu, S; Luo, P; Qin, X; Sun, A; Wang, X; Wu, Q; Zhu, X	1
Dou, Y; Jay Smeyne, R; Jiao, Y; Lockwood, G; Pani, A	1
Li, Z; Pi, R; Shen, W; Wang, L	1
Benazzouz, A; Bouabid, S; De Deurwaerdère, P; Faggiani, E; Lakhdar-Ghazal, N; Tinakoua, A	1
Rajini, PS; Rao, SV; Yenisetti, SC	1
Dikalova, YV; Khudoerkov, RM; Sheloukhova, LI; Voronkov, DN	1
Ganini, D; Kumar, A; Mason, RP	1
Jimenez-Del-Rio, M; Quintero-Espinosa, D; Velez-Pardo, C	1
Jimenez-Del-Rio, M; Ortega-Arellano, HF; Velez-Pardo, C	1
Chau, KY; Cooper, JM; Korlipara, LV; Schapira, AH	1
Fitał, M; Kolasiewicz, W; Kuter, K; Nowak, P; Ossowska, K; Songin, M; Strosznajder, JB	1
Gómez-Pastor, R; Lavara-Culebras, E; Matallana, E; Muñoz-Soriano, V; Paricio, N	1
Bhudhikanok, GS; Blair, A; Cambi, F; Chade, AR; Comyns, K; Fernandez, HH; Goldman, SM; Hoppin, JA; Kamel, F; Kasten, M; Korell, M; Langston, JW; Marras, C; Meng, C; Priestley, B; Richards, MB; Ross, GW; Sandler, DP; Tanner, CM; Umbach, DM	1
Bethune, C; Bobyn, J; Clarke, M; Hayley, S; Litteljohn, D; Mangano, EN; Peters, S; So, R	1
Bagatini, PB; Bernardino, GC; Coelho, GP; de Oliveira, RM; Paim, MF; Rodrigues, MF; Saur, L; Schirmer, H; Silva, DV; Souto, AA; Vianna, MR; Xavier, LL	1
Cai, XY; Chen, RR; He, DF; Xu, HY	1
Bethune, C; Hayley, S; Litteljohn, D; Nelson, E	1
Cai, X; Chen, R; He, D; Xu, H	1
Brent, J; Schaeffer, TH	1
Kim, H; Kim, J; Kim, K; Kim, SH; Yim, J	1
Ahmad, I; Kumar, A; Kumar, V; Pandey, HP; Patel, DK; Shukla, S; Singh, BK; Singh, C; Srivastava, G	1
Credle, J; Duka, V; Jones, J; Lee, JH; Oaks, AW; Sidhu, A; Wills, J	1
Dixit, A; Patel, DK; Prakash, O; Singh, MP; Srivastava, G; Yadav, S	1
Bobyn, J; Clarke, M; Gandhi, A; Hayley, S; Mangano, EN; Moloney, K; Nelson, E	1
Bonilla-Ramirez, L; Jimenez-Del-Rio, M; Velez-Pardo, C	1
Colosio, C; Moretto, A	1
Cory-Slechta, DA; Di Monte, DA; Langston, JW; Manning-Bog, AB; McCormack, AL; Thiffault, C; Thiruchelvam, M	1
Bolin, LM; Di Monte, DA; Manning-Bog, AB; McCormack, AL; Purisai, MG	1
Fujimaru, S; Matsubara, K; Ohtaki, K; Saito, O; Shimizu, K; Shiono, H	1
Cicchetti, F; Ficke, BW; Gross, RE; Jimenez, L; Lapointe, N; Roberge-Tremblay, A; Saint-Pierre, M	1
An, JJ; Cho, SW; Choi, HS; Choi, JH; Choi, SY; Eum, WS; Hwang, SI; Kang, JH; Kang, TC; Kim, DW; Kim, SY; Kwon, HJ; Kwon, OS; Lee, SH; Park, J; Won, MH; Yoo, KY	1
Biedka, I; Bortel, A; Dabrowska, J; Kuter, K; Nowak, P; Ossowska, K; Rommelspacher, H; Schulze, G; Smiałowska, M; Wardas, J; Wierońska, J; Zieba, B	1
Hansen, JM; Jones, DP; Miller, GW; Ramachandiran, S; Richardson, JR	1
Cumine, S; Di Monte, DA; Isla, MZ; Li, J; McCormack, AL; Purisai, MG	1
Bowling, K; Chaudhuri, A; Funderburk, C; Inamdar, A; Lawal, H; O'Donnell, JM; Wang, Z	1
Biedka, I; Konieczny, J; Kuter, K; Nowak, P; Ossowska, K; Pietraszek, M; Roczniak, W; Smiałowska, M; Wardas, J; Wierońska, J; Wolfarth, S; Zieba, B	1
Chen, L; Ding, Y; Kang, UJ; Yang, W; Zhuang, X	1
Miller, GW	1
Cory-Slechta, DA; Di Monte, DA; Thiruchelvam, M	1
Hayley, S; Mangano, EN	1
Gavin, T; LoPachin, RM	1
James-Kracke, M; Miller, RL; Sun, AY; Sun, GY	1
Baggs, RB; Brockel, BJ; Cory-Slechta, DA; Richfield, EK; Thiruchelvam, M	1

Reviews

6 review(s) available for paraquat and Parkinsonian Disorders

Article	Year
Chemical and Genetic Zebrafish Models to Define Mechanisms of and Treatments for Dopaminergic Neurodegeneration. International journal of molecular sciences, 2020, Aug-20, Volume: 21, Issue:17 Topics: Animals; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Gene Knockdown Techniques; Neurotoxicity Syndromes; Oxidopamine; Paraquat; Parkinson Disease; Parkinsonian Disorders; Protein Serine-Threonine Kinases; Rotenone; Zebrafish; Zebrafish Proteins	2020
Neurotoxin-Induced Rodent Models of Parkinson's Disease: Benefits and Drawbacks. Neurotoxicity research, 2021, Volume: 39, Issue:3 Topics: Animals; Disease Models, Animal; Dopaminergic Neurons; Humans; Neurotoxins; Oxidopamine; Paraquat; Parkinsonian Disorders; Rodentia; Substantia Nigra	2021
How Parkinsonian toxins dysregulate the autophagy machinery. International journal of molecular sciences, 2013, Nov-08, Volume: 14, Issue:11 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Autophagy; Humans; Methamphetamine; Mitophagy; MPTP Poisoning; Neurotoxins; Oxidopamine; Paraquat; Parkinsonian Disorders; Rotenone	2013
Systematic review of parkinsonian syndromes in short- and long-term survivors of paraquat poisoning. Journal of occupational and environmental medicine, 2011, Volume: 53, Issue:11 Topics: Herbicides; Humans; Paraquat; Parkinsonian Disorders; Survivors	2011
The role of pesticide exposure in the genesis of Parkinson's disease: epidemiological studies and experimental data. Toxicology, 2013, May-10, Volume: 307 Topics: Animals; Animals, Genetically Modified; Disease Models, Animal; Environmental Exposure; Herbicides; Humans; Paraquat; Parkinson Disease, Secondary; Parkinsonian Disorders	2013
Oxidative and inflammatory pathways in Parkinson's disease. Neurochemical research, 2009, Volume: 34, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Herbicides; Humans; Inflammation; Lipopolysaccharides; Microglia; Mitogen-Activated Protein Kinases; NADPH Oxidases; Neurotoxins; Nitric Oxide Synthase; Oxidative Stress; Oxidopamine; Paraquat; Parkinson Disease; Parkinsonian Disorders; Protein Kinase C; Rotenone	2009

Other Studies

59 other study(ies) available for paraquat and Parkinsonian Disorders

Article	Year
Age-related tolerance to paraquat-induced parkinsonism in Drosophila melanogaster. Toxicology letters, 2022, May-15, Volume: 361 Topics: Animals; Antioxidants; Drosophila melanogaster; Herbicides; Paraquat; Parkinsonian Disorders	2022
Paraquat exposure induces Parkinsonism by altering lipid profile and evoking neuroinflammation in the midbrain. Environment international, 2022, Volume: 169 Topics: alpha-Synuclein; Animals; Ceramides; Cytokines; Environmental Pollutants; Glycerides; Glycerophospholipids; Herbicides; Humans; Lipopolysaccharides; Mesencephalon; Mice; Mice, Inbred C57BL; Neuroinflammatory Diseases; Neurotoxicity Syndromes; Neurotoxins; Paraquat; Parkinson Disease; Parkinsonian Disorders; RNA, Messenger; Sphingolipids	2022
Characterization of the Basic Membrane Properties of Neurons of the Rat Dorsal Motor Nucleus of the Vagus in Paraquat-Induced Models of Parkinsonism. Neuroscience, 2019, 10-15, Volume: 418 Topics: Action Potentials; Animals; Excitatory Postsynaptic Potentials; Lectins; Male; Membranes; Models, Animal; Neurons; Paraquat; Parkinsonian Disorders; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Synapses; Vagus Nerve	2019
Poloxamer 188-mediated anti-inflammatory effect rescues cognitive deficits in paraquat and maneb-induced mouse model of Parkinson's disease. Toxicology, 2020, 04-30, Volume: 436 Topics: Animals; Anti-Inflammatory Agents; Behavior, Animal; Cell Proliferation; Cognition; Cognitive Dysfunction; Disease Models, Animal; Dopaminergic Neurons; Hippocampus; Inflammation Mediators; Male; Maneb; Maze Learning; Mice, Inbred C57BL; Microglia; Nerve Degeneration; Paraquat; Parkinsonian Disorders; Pars Compacta; Phagocytosis; Poloxamer; Recognition, Psychology; Synapses	2020
Integrin CD11b mediates locus coeruleus noradrenergic neurodegeneration in a mouse Parkinson's disease model. Journal of neuroinflammation, 2020, May-06, Volume: 17, Issue:1 Topics: Adrenergic Neurons; Animals; CD11b Antigen; Disease Models, Animal; Inflammasomes; Locus Coeruleus; Male; Maneb; Mice; Mice, Inbred C57BL; Mice, Knockout; Microglia; Nerve Degeneration; NLR Family, Pyrin Domain-Containing 3 Protein; Paraquat; Parkinsonian Disorders; Pesticides	2020
Investigation of anti-Parkinson activity of dicyclomine. The International journal of neuroscience, 2022, Volume: 132, Issue:4 Topics: Animals; Dicyclomine; Disease Models, Animal; Dopamine; Haloperidol; Mice; Paraquat; Parkinson Disease, Secondary; Parkinsonian Disorders; Substantia Nigra	2022
A novel idea for establishing Parkinson's disease mouse model by intranasal administration of paraquat. Neurological research, 2021, Volume: 43, Issue:4 Topics: 3,4-Dihydroxyphenylacetic Acid; Administration, Intranasal; Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Male; Mice; Mice, Inbred C57BL; Paraquat; Parkinsonian Disorders; Poloxamer	2021
Inhibition of NLRP3 inflammasome by glibenclamide attenuated dopaminergic neurodegeneration and motor deficits in paraquat and maneb-induced mouse Parkinson's disease model. Toxicology letters, 2021, Oct-01, Volume: 349 Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Antiparkinson Agents; Disease Models, Animal; Dopaminergic Neurons; Glyburide; Inflammasomes; Lipid Peroxidation; Male; Maneb; Mice, Inbred C57BL; Microglia; Motor Activity; NADPH Oxidase 2; Nerve Degeneration; Neuroprotective Agents; NF-kappa B; Nitric Oxide Synthase Type II; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Paraquat; Parkinsonian Disorders	2021
Paraquat exposure-induced Parkinson's disease-like symptoms and oxidative stress in Drosophila melanogaster: Neuroprotective effect of Bougainvillea glabra Choisy. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 95 Topics: Animals; Dose-Response Relationship, Drug; Drosophila melanogaster; Herbicides; Male; Neuroprotective Agents; Nyctaginaceae; Oxidative Stress; Paraquat; Parkinsonian Disorders; Plant Extracts; Plant Leaves; Treatment Outcome	2017
Mutation of hop-1 and pink-1 attenuates vulnerability of neurotoxicity in C. elegans: the role of mitochondria-associated membrane proteins in Parkinsonism. Experimental neurology, 2018, Volume: 309 Topics: Adenosine Triphosphate; Animals; Animals, Genetically Modified; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Green Fluorescent Proteins; Membrane Potential, Mitochondrial; Membrane Proteins; Microscopy, Electron, Transmission; Mitochondria; Mitochondrial Diseases; Mitochondrial Proteins; Movement; Mutation; Paraquat; Parkinsonian Disorders; Protein Serine-Threonine Kinases; Rotenone	2018
Glimepiride prevents paraquat-induced Parkinsonism in mice: involvement of oxidative stress and neuroinflammation. Fundamental & clinical pharmacology, 2019, Volume: 33, Issue:3 Topics: Animals; Antioxidants; Cytokines; Dose-Response Relationship, Drug; Inflammation; Lipid Peroxidation; Male; Maze Learning; Memory Disorders; Mice; Neuroprotective Agents; Oxidative Stress; Paraquat; Parkinsonian Disorders; Sulfonylurea Compounds; Superoxide Dismutase	2019
Neuroprotective Activity of Some Marine Fungal Metabolites in the 6-Hydroxydopamin- and Paraquat-Induced Parkinson's Disease Models. Marine drugs, 2018, Nov-21, Volume: 16, Issue:11 Topics: Alkaloids; Animals; Antioxidants; Antiparkinson Agents; Aquatic Organisms; Aspergillus; Biological Products; Cell Line, Tumor; Cell Survival; Melatonin; Mice; Neuroprotective Agents; Oxidopamine; Paraquat; Parkinsonian Disorders; Penicillium; Polyketides; Reactive Oxygen Species	2018
Conditional Haploinsufficiency of β-Catenin Aggravates Neuronal Damage in a Paraquat-Based Mouse Model of Parkinson Disease. Molecular neurobiology, 2019, Volume: 56, Issue:7 Topics: Animals; beta Catenin; Dopaminergic Neurons; Female; Haploinsufficiency; Male; Mice; Mice, Knockout; Paraquat; Parkinsonian Disorders	2019
Central nervous system agents in medicinal chemistry, 2019, Volume: 19, Issue:1 Topics: Animals; Bacopa; Brain; Dietary Supplements; Exploratory Behavior; Male; Mice; Oxidative Stress; Paraquat; Parkinsonian Disorders; Phenotype	2019
Altered gastric tone and motility response to brain-stem dopamine in a rat model of parkinsonism. American journal of physiology. Gastrointestinal and liver physiology, 2019, 07-01, Volume: 317, Issue:1 Topics: Animals; Brain Stem; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Gastrointestinal Motility; Male; Neural Inhibition; Neuronal Plasticity; Paraquat; Parkinsonian Disorders; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Stomach; Vagus Nerve	2019
Neuroprotective role of Withania somnifera root extract in maneb-paraquat induced mouse model of parkinsonism. Neurochemical research, 2013, Volume: 38, Issue:5 Topics: Animals; Disease Models, Animal; Maneb; Mice; Neuroprotective Agents; Paraquat; Parkinsonian Disorders; Plant Extracts; Plant Roots; Withania	2013
Mucuna pruriens seed extract reduces oxidative stress in nigrostriatal tissue and improves neurobehavioral activity in paraquat-induced Parkinsonian mouse model. Neurochemistry international, 2013, Volume: 62, Issue:8 Topics: Animals; Behavior, Animal; Catalase; Corpus Striatum; Disease Models, Animal; Male; Malondialdehyde; Mice; Mucuna; Oxidative Stress; Paraquat; Parkinsonian Disorders; Plant Extracts; Seeds; Substantia Nigra	2013
Silymarin- and melatonin-mediated changes in the expression of selected genes in pesticides-induced Parkinsonism. Molecular and cellular biochemistry, 2013, Volume: 384, Issue:1-2 Topics: Animals; Antioxidants; Apoptosis; Cell Cycle; Disease Models, Animal; Gene Expression Regulation; Inflammation; Ion Channels; Male; Maneb; Melatonin; Mice; Mitochondria; Oxidative Stress; Paraquat; Parkinsonian Disorders; Pesticides; Signal Transduction; Silymarin	2013
Heat shock protein-70 (Hsp-70) suppresses paraquat-induced neurodegeneration by inhibiting JNK and caspase-3 activation in Drosophila model of Parkinson's disease. PloS one, 2014, Volume: 9, Issue:6 Topics: Animals; Apoptosis; Caspase 3; Disease Models, Animal; Dopaminergic Neurons; Drosophila melanogaster; Drosophila Proteins; HSP70 Heat-Shock Proteins; JNK Mitogen-Activated Protein Kinases; Motor Activity; Oxidative Stress; Paraquat; Parkinsonian Disorders; Up-Regulation	2014
Soluble Epoxide Hydrolase Deficiency or Inhibition Attenuates MPTP-Induced Parkinsonism. Molecular neurobiology, 2015, Volume: 52, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 8,11,14-Eicosatrienoic Acid; Adamantane; Animals; Behavior, Animal; Cell Survival; Cells, Cultured; Dopaminergic Neurons; Epoxide Hydrolases; Lauric Acids; Male; Mice, Inbred C57BL; Mice, Knockout; Neuroprotective Agents; Paraquat; Parkinsonian Disorders; Rotarod Performance Test; Solubility; Substantia Nigra; Tyrosine 3-Monooxygenase; Up-Regulation	2015
Acute Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) or Paraquat on Core Temperature in C57BL/6J Mice. Journal of Parkinson's disease, 2015, Volume: 5, Issue:2 Topics: Animals; Body Temperature; Corpus Striatum; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; MPTP Poisoning; Paraquat; Parkinsonian Disorders; Purines; Substantia Nigra	2015
L-F001, a multifunctional ROCK inhibitor prevents paraquat-induced cell death through attenuating ER stress and mitochondrial dysfunction in PC12 cells. Biochemical and biophysical research communications, 2015, Aug-28, Volume: 464, Issue:3 Topics: Animals; Antiparkinson Agents; Azepines; Cell Death; Dopaminergic Neurons; Endoplasmic Reticulum Stress; Glutathione; Mitochondria; Paraquat; Parkinsonian Disorders; PC12 Cells; Protein Kinase Inhibitors; Rats; Reactive Oxygen Species; rho-Associated Kinases; Sulfonamides	2015
The impact of combined administration of paraquat and maneb on motor and non-motor functions in the rat. Neuroscience, 2015, Dec-17, Volume: 311 Topics: Animals; Anxiety Disorders; Central Nervous System Agents; Corpus Striatum; Depressive Disorder; Dopamine; Male; Maneb; Motor Activity; Neurons; Norepinephrine; Paraquat; Parkinsonian Disorders; Rats, Sprague-Dawley; Serotonin; Subthalamic Nucleus	2015
Evidence of neuroprotective effects of saffron and crocin in a Drosophila model of parkinsonism. Neurotoxicology, 2016, Volume: 52 Topics: Acetylcholinesterase; Animals; Antioxidants; Biomarkers; Carotenoids; Crocus; Disease Models, Animal; Dopamine; Drosophila melanogaster; Glutathione; Hydrogen Peroxide; Locomotion; Longevity; Mitochondria; Neuroprotective Agents; Nitric Oxide; Oxidative Stress; Paraquat; Parkinsonian Disorders; Phytotherapy; Plant Extracts; Protein Carbonylation; Reactive Oxygen Species; Rotenone; Sulfhydryl Compounds	2016
Quantitative Evaluation of Changes in the Striatal Astrocyte Axons in Simulated Parkinsonism. Bulletin of experimental biology and medicine, 2016, Volume: 160, Issue:4 Topics: Animals; Astrocytes; Axons; Corpus Striatum; Glial Fibrillary Acidic Protein; Male; Oxidopamine; Paraquat; Parkinsonian Disorders; Rats; Rats, Wistar; Rotenone	2016
Role of cytochrome c in α-synuclein radical formation: implications of α-synuclein in neuronal death in Maneb- and paraquat-induced model of Parkinson's disease. Molecular neurodegeneration, 2016, 11-24, Volume: 11, Issue:1 Topics: alpha-Synuclein; Animals; Cell Death; Cytochromes c; Free Radicals; Immunohistochemistry; Male; Maneb; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Confocal; Neurons; Oligonucleotide Array Sequence Analysis; Oxidative Stress; Paraquat; Parkinsonian Disorders; Pesticides	2016
Knockdown transgenic Lrrk Drosophila resists paraquat-induced locomotor impairment and neurodegeneration: A therapeutic strategy for Parkinson's disease. Brain research, 2017, 02-15, Volume: 1657 Topics: Animals; Animals, Genetically Modified; Antioxidants; Cell Survival; Dopamine; Dopaminergic Neurons; Drosophila melanogaster; Drosophila Proteins; Female; Minocycline; Motor Activity; Oxidative Stress; Paraquat; Parkinsonian Disorders; Protein Serine-Threonine Kinases; RNA Interference; RNAi Therapeutics; Tyrosine 3-Monooxygenase	2017
Minocycline protects, rescues and prevents knockdown transgenic parkin Drosophila against paraquat/iron toxicity: Implications for autosomic recessive juvenile parkinsonism. Neurotoxicology, 2017, Volume: 60 Topics: Animals; Animals, Genetically Modified; Brain; Dopaminergic Neurons; Drosophila melanogaster; Drosophila Proteins; Female; Gene Knockdown Techniques; Iron; Lipid Peroxidation; Male; Minocycline; Motor Activity; Neuroprotective Agents; Oxidative Stress; Paraquat; Parkinsonian Disorders; Survival Analysis; Ubiquitin-Protein Ligases	2017
Protection against paraquat and A53T alpha-synuclein toxicity by cabergoline is partially mediated by dopamine receptors. Journal of the neurological sciences, 2009, Mar-15, Volume: 278, Issue:1-2 Topics: alpha-Synuclein; Analysis of Variance; Apoptosis; Blotting, Western; Cabergoline; Caspase 3; Cell Line; Enzyme Activation; Ergolines; Glutathione; Humans; Immunohistochemistry; JNK Mitogen-Activated Protein Kinases; Lactate Dehydrogenases; Membrane Potential, Mitochondrial; Paraquat; Parkinsonian Disorders; Reactive Oxygen Species; Receptors, Dopamine D2	2009
Glycogen synthase kinase 3β and its phosphorylated form (Y216) in the paraquat-induced model of parkinsonism. Neurotoxicity research, 2011, Volume: 19, Issue:1 Topics: Animals; Corpus Striatum; Disease Models, Animal; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Male; Mesencephalon; Motor Activity; Paraquat; Parkinsonian Disorders; Phosphorylation; Rats; Rats, Wistar; Substantia Nigra; Tyrosine	2011
Effects of pharmacological agents on the lifespan phenotype of Drosophila DJ-1beta mutants. Gene, 2010, Aug-15, Volume: 462, Issue:1-2 Topics: Animals; Antioxidants; Brain; Dopamine; Drosophila; Mutation; Oxidative Stress; Paraquat; Parkinson Disease; Parkinsonian Disorders; Phenotype; Reactive Oxygen Species	2010
Rotenone, paraquat, and Parkinson's disease. Environmental health perspectives, 2011, Volume: 119, Issue:6 Topics: Aged; Case-Control Studies; Female; Herbicides; Humans; Insecticides; Iowa; Male; Middle Aged; Mitochondria; North Carolina; Occupational Exposure; Oxidative Stress; Paraquat; Parkinson Disease; Parkinsonian Disorders; Rotenone	2011
Granulocyte macrophage-colony stimulating factor protects against substantia nigra dopaminergic cell loss in an environmental toxin model of Parkinson's disease. Neurobiology of disease, 2011, Volume: 43, Issue:1 Topics: Animals; Cell Death; Disease Models, Animal; Dopamine; Granulocyte-Macrophage Colony-Stimulating Factor; Herbicides; Injections, Intralesional; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Neurons; Neuroprotective Agents; Paraquat; Parkinsonian Disorders; Substantia Nigra	2011
The role of calcium channel blockers and resveratrol in the prevention of paraquat-induced parkinsonism in Drosophila melanogaster: a locomotor analysis. Invertebrate neuroscience : IN, 2011, Volume: 11, Issue:1 Topics: Animals; Antioxidants; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Disease Models, Animal; Dopamine; Drosophila melanogaster; Nerve Degeneration; Paraquat; Parkinsonian Disorders; Resveratrol; Stilbenes; Substantia Nigra	2011
[Effects of co-exposure to paraquat and maneb on system of substantial nigra and striatum in rats]. Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 2011, Volume: 29, Issue:1 Topics: Animals; Corpus Striatum; Male; Maneb; Paraquat; Parkinsonian Disorders; Pesticides; Rats; Rats, Sprague-Dawley; Substantia Nigra	2011
The effects of paraquat on regional brain neurotransmitter activity, hippocampal BDNF and behavioural function in female mice. Neuroscience letters, 2011, Sep-20, Volume: 502, Issue:3 Topics: Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Female; Herbicides; Hippocampus; Mice; Mice, Inbred C57BL; Neurotransmitter Agents; Paraquat; Parkinsonian Disorders; Synaptic Transmission	2011
Differential effects of activating D1 and D2 receptors on electrophysiology of neostriatal neurons in a rat model of Parkinson's disease induced by paraquat and maneb. Neuroscience research, 2011, Volume: 71, Issue:4 Topics: Animals; Disease Models, Animal; Electrophysiological Phenomena; Fungicides, Industrial; Herbicides; Male; Maneb; Neocortex; Paraquat; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2	2011
Glutathione s-transferase omega 1 activity is sufficient to suppress neurodegeneration in a Drosophila model of Parkinson disease. The Journal of biological chemistry, 2012, Feb-24, Volume: 287, Issue:9 Topics: Animals; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins; Glutathione Transferase; Herbicides; JNK Mitogen-Activated Protein Kinases; Male; Mitochondrial Proton-Translocating ATPases; Mutagenesis, Site-Directed; Nerve Degeneration; Oxidative Stress; Paraquat; Parkinsonian Disorders; Phenotype; Signal Transduction; Tubulin; Ubiquitin-Protein Ligases; Unfolded Protein Response	2012
Involvement of NADPH oxidase and glutathione in zinc-induced dopaminergic neurodegeneration in rats: similarity with paraquat neurotoxicity. Brain research, 2012, Feb-15, Volume: 1438 Topics: Acetophenones; Acetylcysteine; Animals; Apoptosis; Caspases; CD11b Antigen; Corpus Striatum; Cytochromes c; Dopamine; Dopaminergic Neurons; Enzyme Inhibitors; Glutathione; Male; Membrane Glycoproteins; Mitochondria; Motor Activity; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Paraquat; Parkinsonian Disorders; Phosphoproteins; Rats; Rats, Wistar; Serotonin; Substantia Nigra; Tyrosine 3-Monooxygenase	2012
Paraquat, but not maneb, induces synucleinopathy and tauopathy in striata of mice through inhibition of proteasomal and autophagic pathways. PloS one, 2012, Volume: 7, Issue:1 Topics: alpha-Synuclein; Animals; Autophagy; Case-Control Studies; Corpus Striatum; Down-Regulation; Fungicides, Industrial; Herbicides; Humans; Male; Maneb; Mice; Mice, Inbred C57BL; Paraquat; Parkinsonian Disorders; Proteasome Endopeptidase Complex; Signal Transduction; Tauopathies	2012
Resveratrol potentiates cytochrome P450 2 d22-mediated neuroprotection in maneb- and paraquat-induced parkinsonism in the mouse. Free radical biology & medicine, 2012, Apr-15, Volume: 52, Issue:8 Topics: Animals; Blotting, Western; Chromatography, High Pressure Liquid; Corpus Striatum; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Dopamine; Fungicides, Industrial; Herbicides; Male; Maneb; Mice; Neuroprotective Agents; Paraquat; Parkinsonian Disorders; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes	2012
Viral-toxin interactions and Parkinson's disease: poly I:C priming enhanced the neurodegenerative effects of paraquat. Journal of neuroinflammation, 2012, May-04, Volume: 9 Topics: Animals; Antiviral Agents; Corpus Striatum; Disease Models, Animal; Drug Synergism; Male; Mice; Mice, Inbred C57BL; Nerve Degeneration; Paraquat; Parkinsonian Disorders; Poly I-C	2012
Low doses of paraquat and polyphenols prolong life span and locomotor activity in knock-down parkin Drosophila melanogaster exposed to oxidative stress stimuli: implication in autosomal recessive juvenile parkinsonism. Gene, 2013, Jan-10, Volume: 512, Issue:2 Topics: Animals; Animals, Genetically Modified; Antioxidants; Disease Models, Animal; Dopaminergic Neurons; Drosophila melanogaster; Drosophila Proteins; Gene Knockdown Techniques; Herbicides; Humans; Longevity; Motor Activity; Oxidative Stress; Paraquat; Parkinsonian Disorders; Polyphenols; Ubiquitin-Protein Ligases	2013
Environmental risk factors and Parkinson's disease: selective degeneration of nigral dopaminergic neurons caused by the herbicide paraquat. Neurobiology of disease, 2002, Volume: 10, Issue:2 Topics: 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Biomarkers; Dopamine; Environmental Exposure; gamma-Aminobutyric Acid; Gliosis; Herbicides; Homovanillic Acid; Humans; Injections, Intraperitoneal; Male; Mesencephalon; Mice; Mice, Inbred C57BL; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Paraquat; Parkinson Disease; Parkinson Disease, Secondary; Parkinsonian Disorders; Risk Factors; Substantia Nigra; Tyrosine 3-Monooxygenase	2002
Alpha-synuclein overexpression protects against paraquat-induced neurodegeneration. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, Apr-15, Volume: 23, Issue:8 Topics: alpha-Synuclein; Animals; Cell Count; Cell Survival; HSP70 Heat-Shock Proteins; Humans; Macromolecular Substances; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Nerve Tissue Proteins; Neurodegenerative Diseases; Neurons; Paraquat; Parkinsonian Disorders; Promoter Regions, Genetic; Silver Staining; Substantia Nigra; Synucleins; Tyrosine 3-Monooxygenase	2003
Paraquat induces long-lasting dopamine overflow through the excitotoxic pathway in the striatum of freely moving rats. Brain research, 2003, Jun-27, Volume: 976, Issue:2 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine Plasma Membrane Transport Proteins; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Herbicides; Homovanillic Acid; Male; Membrane Glycoproteins; Membrane Transport Proteins; Motor Activity; Nerve Tissue Proteins; Neuroprotective Agents; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Paraquat; Parkinsonian Disorders; Quinoxalines; Rats; Rats, Wistar; Selegiline	2003
Systemic exposure to paraquat and maneb models early Parkinson's disease in young adult rats. Neurobiology of disease, 2005, Volume: 20, Issue:2 Topics: Age of Onset; Animals; Cells, Cultured; Coculture Techniques; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Encephalitis; Fungicides, Industrial; Gliosis; Herbicides; Male; Maneb; Microglia; Nerve Degeneration; Neurons; Paraquat; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Rats, Wistar; Substantia Nigra	2005
Transduced Tat-alpha-synuclein protects against oxidative stress in vitro and in vivo. Journal of biochemistry and molecular biology, 2006, May-31, Volume: 39, Issue:3 Topics: alpha-Synuclein; Animals; Astrocytes; Cell Death; Cell Survival; Gene Products, tat; Genetic Vectors; HSP70 Heat-Shock Proteins; Humans; Male; Mice; Mice, Inbred C57BL; Mutation; Nerve Degeneration; Neurons; Oxidative Stress; Paraquat; Parkinsonian Disorders; Protein Transport; Recombinant Fusion Proteins; Transduction, Genetic	2006
Degeneration of dopaminergic mesocortical neurons and activation of compensatory processes induced by a long-term paraquat administration in rats: implications for Parkinson's disease. Neuroscience, 2006, Sep-15, Volume: 141, Issue:4 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Cerebral Cortex; Chromatography, High Pressure Liquid; Disease Models, Animal; Dopamine; Herbicides; Homovanillic Acid; Immunohistochemistry; Male; Nerve Degeneration; Neurons; Paraquat; Parkinsonian Disorders; Rats; Rats, Wistar; Tyrosine 3-Monooxygenase; Ventral Tegmental Area	2006
Divergent mechanisms of paraquat, MPP+, and rotenone toxicity: oxidation of thioredoxin and caspase-3 activation. Toxicological sciences : an official journal of the Society of Toxicology, 2007, Volume: 95, Issue:1 Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Caspase 3; Cell Line, Tumor; Cell Survival; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Enzyme Activation; Herbicides; Humans; Insecticides; JNK Mitogen-Activated Protein Kinases; Mitochondrial Proteins; Neurons; Oxidation-Reduction; Paraquat; Parkinsonian Disorders; Rotenone; Thioredoxins; Transfection	2007
Microglial activation as a priming event leading to paraquat-induced dopaminergic cell degeneration. Neurobiology of disease, 2007, Volume: 25, Issue:2 Topics: Animals; Anti-Inflammatory Agents; Biomarkers; Dopamine; Encephalitis; Gliosis; Herbicides; Inflammation Mediators; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Microglia; Minocycline; NADPH Oxidases; Nerve Degeneration; Neurotoxins; Oxidative Stress; Paraquat; Parkinsonian Disorders; Substantia Nigra	2007
Interaction of genetic and environmental factors in a Drosophila parkinsonism model. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Mar-07, Volume: 27, Issue:10 Topics: Animals; Biopterins; Catalase; Cell Aggregation; Disease Models, Animal; Dopamine; Drosophila; Drosophila Proteins; Dyskinesia, Drug-Induced; Female; Gene Expression Regulation; Genetic Predisposition to Disease; Hazardous Substances; Herbicides; Homeostasis; Longevity; Male; Mutation; Neurons; Paraquat; Parkinsonian Disorders	2007
Toxic influence of subchronic paraquat administration on dopaminergic neurons in rats. Brain research, 2007, Jun-25, Volume: 1155 Topics: Animals; Caudate Nucleus; Dopamine; Drug Administration Schedule; Gene Expression Regulation, Enzymologic; Glutamate Decarboxylase; Herbicides; Isoenzymes; Nerve Degeneration; Neurons; Paraquat; Parkinsonian Disorders; Putamen; Rats; RNA, Messenger	2007
Paraquat induces dopaminergic dysfunction and proteasome impairment in DJ-1-deficient mice. Human molecular genetics, 2007, Dec-01, Volume: 16, Issue:23 Topics: Adenosine Triphosphate; Animals; Brain; Dopamine; Herbicides; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2; Oncogene Proteins; Paraquat; Parkinsonian Disorders; Peroxiredoxins; Proteasome Endopeptidase Complex; Protein Deglycase DJ-1; Psychomotor Performance; Ubiquitination	2007
Paraquat: the red herring of Parkinson's disease research. Toxicological sciences : an official journal of the Society of Toxicology, 2007, Volume: 100, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Disease Models, Animal; Humans; Molecular Structure; Oxidative Stress; Paraquat; Parkinsonian Disorders; Reproducibility of Results; Structure-Activity Relationship	2007
Letter regarding: "Paraquat: the red herring of Parkinson's disease research". Toxicological sciences : an official journal of the Society of Toxicology, 2008, Volume: 103, Issue:1 Topics: Herbicides; Humans; Paraquat; Parkinsonian Disorders	2008
Inflammatory priming of the substantia nigra influences the impact of later paraquat exposure: Neuroimmune sensitization of neurodegeneration. Neurobiology of aging, 2009, Volume: 30, Issue:9 Topics: Animals; Cytokines; Drug Administration Schedule; Drug Interactions; Drug Synergism; Encephalitis; Hazardous Substances; Herbicides; Inflammation Mediators; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Microglia; Nerve Degeneration; Neuroimmunomodulation; Paraquat; Parkinsonian Disorders; Substantia Nigra	2009
Response to "Paraquat: the red herring of Parkinson's disease research". Toxicological sciences : an official journal of the Society of Toxicology, 2008, Volume: 103, Issue:1 Topics: Herbicides; Humans; Paraquat; Parkinsonian Disorders	2008
Potentiated and preferential effects of combined paraquat and maneb on nigrostriatal dopamine systems: environmental risk factors for Parkinson's disease? Brain research, 2000, Aug-11, Volume: 873, Issue:2 Topics: Animals; Body Weight; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Environmental Exposure; Lung; Male; Maneb; Mice; Mice, Inbred C57BL; Motor Activity; Neostriatum; Neural Pathways; Neurons; Paraquat; Parkinsonian Disorders; Risk Factors; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase	2000