Page last updated: 2024-08-21

paraquat and Nerve Degeneration

paraquat has been researched along with Nerve Degeneration in 52 studies

Research

Studies (52)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (3.85)	18.2507
2000's	22 (42.31)	29.6817
2010's	23 (44.23)	24.3611
2020's	5 (9.62)	2.80

Authors

Authors	Studies
Naidu, R; See, WZC; Tang, KS	1
Liu, CY; Wang, YL; Yang, HM; Zhang, XF; Zhou, YT	1
Ding, W; Hong, X; Ji, D; Lin, H; Wu, F	1
Hou, L; Huang, R; Qiu, X; Qu, X; Wang, Q; Zhao, X	1
Hou, L; Qiu, X; Wang, Q; Zhang, C; Zhao, X	1
Gartner, A; Jongsma, E; Offenburger, SL	1
Coakley, S; Gartner, A; Hilliard, MA; Ho, XY; Offenburger, SL; Tachie-Menson, T	1
Morioka, H; Nishio, R; Takeda, A; Takeuchi, A; Tamano, H	1
Hou, L; Huang, R; Sun, F; Wang, Q; Zhang, L	1
Beck, M; Botham, PA; Breckenridge, CB; Butt, M; Cook, AR; Mathews, JM; Minnema, D; Smith, LL; Sturgess, NC; Tisdel, MO; Travis, KZ; Wolf, JC; Zadory, D	1
Abdin, MZ; Chaouhan, HS; Kar Chowdhuri, D; Patel, DK; Pragya, P; Shukla, AK	1
Chaouhan, HS; Chowdhuri, DK; Mudiam, MKR; Patel, DK; Pragya, P; Ratnasekhar, C; Shukla, AK	1
Arrant, AE; Bodhicharla, RK; Cyr, DD; González-Hunt, CP; Hammarlund, M; Kosmaczewski, SG; Leung, MC; Margillo, KM; McKeever, MG; Meyer, JN; Ryde, IT	1
Hu, M; Huang, Z; Li, H; Ma, CW; Ma, F; Shi, R; Xiang, Y; Xiao, L; Zhang, J	1
Che, Y; Hou, L; Liu, X; Sun, F; Wang, H; Wang, K; Wang, Q; Zhang, C; Zhao, X; Zhou, X	1
Fischer, LR; Glass, JD	1
Berry, C; La Vecchia, C; Nicotera, P	1
Irizarry, MC; Kachroo, A; Schwarzschild, MA	1
Ahmad, I; Kumar, A; Pandey, HP; Patel, DK; Shukla, S; Singh, BK; Singh, C	1
Andersen, JK; Oo, ML; Peng, J	1
Bagatini, PB; Bernardino, GC; Coelho, GP; de Oliveira, RM; Paim, MF; Rodrigues, MF; Saur, L; Schirmer, H; Silva, DV; Souto, AA; Vianna, MR; Xavier, LL	1
Chesselet, MF; Giza, CC; Hovda, D; Hutson, CB; Lazo, CR; Mortazavi, F	1
Anantharam, V; Jin, H; Kanthasamy, A; Kanthasamy, AG; Song, C	1
Bhattacharyya, A; Chakrabarti, N; Mitra, S	1
Kim, H; Kim, J; Kim, K; Kim, SH; Yim, J	1
Jiao, Y; Lu, L; Smeyne, RJ; Williams, RW	1
Bobyn, J; Clarke, M; Gandhi, A; Hayley, S; Mangano, EN; Moloney, K; Nelson, E	1
Chen, ZY; Edwin Chan, HY; Liang, Y; Ma, KY; Peng, C; Yu, H; Zuo, Y	1
Cory-Slechta, DA; Di Monte, DA; Langston, JW; Manning-Bog, AB; McCormack, AL; Thiffault, C; Thiruchelvam, M	1
Durham, HD; Figlewicz, DA; Kriscenski-Perry, E; Sheu, SS	1
Andersen, JK	1
Besson, MT; Birman, S; Iché, M; Rival, T; Soustelle, L; Strambi, C	1
Uversky, VN	1
Andersen, JK; Atienza, JG; Di Monte, DA; Johnston, LC; McCormack, AL; Vu, S	1
Kadota, S; Li, X; Matsumoto, K; Murakami, Y; Tezuka, Y; Wu, Y	1
Cicchetti, F; Ficke, BW; Gross, RE; Jimenez, L; Lapointe, N; Roberge-Tremblay, A; Saint-Pierre, M	1
Atienza, JG; Di Monte, DA; Langston, JW; McCormack, AL	1
Kordower, JH; O'Malley, J; Soderstrom, K; Steece-Collier, K	1
An, JJ; Cho, SW; Choi, HS; Choi, JH; Choi, SY; Eum, WS; Hwang, SI; Kang, JH; Kang, TC; Kim, DW; Kim, SY; Kwon, HJ; Kwon, OS; Lee, SH; Park, J; Won, MH; Yoo, KY	1
Biedka, I; Bortel, A; Dabrowska, J; Kuter, K; Nowak, P; Ossowska, K; Rommelspacher, H; Schulze, G; Smiałowska, M; Wardas, J; Wierońska, J; Zieba, B	1
Cicchetti, F; Gross, RE; Saint-Pierre, M; Sik, A; Tremblay, ME	1
Achsel, T; Angelini, DF; Bernardi, G; Carrì, MT; Di Penta, A; Maracchioni, A; Totaro, A	1
Cumine, S; Di Monte, DA; Isla, MZ; Li, J; McCormack, AL; Purisai, MG	1
Dias-Santagata, D; Duttaroy, A; Feany, MB; Fulga, TA	1
Biedka, I; Konieczny, J; Kuter, K; Nowak, P; Ossowska, K; Pietraszek, M; Roczniak, W; Smiałowska, M; Wardas, J; Wierońska, J; Wolfarth, S; Zieba, B	1
Andersen, JK; Doctrow, SR; Peng, J; Peng, L; Stevenson, FF	1
Miller, RL; Sun, AY; Sun, GY	1
Cavada, C; Cuadrado, A; de Sagarra, MR; Rojo, AI	1
Hayley, S; Mangano, EN	1
Bagetta, G; Iannone, M; Nisticó, G; Rispoli, V; Rotiroti, D; Vecchio, I	1
Bar-Peled, O; Knudson, M; Korsmeyer, SJ; Rothstein, JD	1
Day, BJ; Li, QY; Patel, M; Pedersen, C	1

Reviews

5 review(s) available for paraquat and Nerve Degeneration

Article	Year
Cellular and Molecular Events Leading to Paraquat-Induced Apoptosis: Mechanistic Insights into Parkinson's Disease Pathophysiology. Molecular neurobiology, 2022, Volume: 59, Issue:6 Topics: Apoptosis; Dopaminergic Neurons; Humans; Nerve Degeneration; Paraquat; Parkinson Disease; Substantia Nigra	2022
Paraquat and Parkinson's disease. Cell death and differentiation, 2010, Volume: 17, Issue:7 Topics: Animals; Apoptosis; Disease Models, Animal; Herbicides; Humans; Mice; Nerve Degeneration; Paraquat; Parkinson Disease; Risk Factors	2010
Paraquat and iron exposure as possible synergistic environmental risk factors in Parkinson's disease. Neurotoxicity research, 2003, Volume: 5, Issue:5 Topics: Dopamine; Drug Synergism; Environmental Pollutants; Herbicides; Humans; Iron; Nerve Degeneration; Nerve Tissue Proteins; Paraquat; Parkinson Disease, Secondary; Risk Factors; Synucleins	2003
Neurotoxicant-induced animal models of Parkinson's disease: understanding the role of rotenone, maneb and paraquat in neurodegeneration. Cell and tissue research, 2004, Volume: 318, Issue:1 Topics: Animals; Disease Models, Animal; Fungicides, Industrial; Herbicides; Maneb; Nerve Degeneration; Neurotoxins; Paraquat; Parkinson Disease; Rotenone; Uncoupling Agents	2004
Neural repair strategies for Parkinson's disease: insights from primate models. Cell transplantation, 2006, Volume: 15, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Cell Transplantation; Deep Brain Stimulation; Disease Models, Animal; Fungicides, Industrial; Glial Cell Line-Derived Neurotrophic Factor; Herbicides; Humans; Maneb; Nerve Degeneration; Oxidopamine; Paraquat; Parkinson Disease; Pesticides; Primates; Rotenone	2006

Other Studies

47 other study(ies) available for paraquat and Nerve Degeneration

Article	Year
A time-course study of microglial activation and dopaminergic neuron loss in the substantia nigra of mice with paraquat-induced Parkinson's disease. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2022, Volume: 164 Topics: Animals; Dopamine; Dopaminergic Neurons; Male; Mice; Mice, Inbred C57BL; Microglia; Nerve Degeneration; Paraquat; Parkinson Disease; Substantia Nigra	2022
Poloxamer 188-mediated anti-inflammatory effect rescues cognitive deficits in paraquat and maneb-induced mouse model of Parkinson's disease. Toxicology, 2020, 04-30, Volume: 436 Topics: Animals; Anti-Inflammatory Agents; Behavior, Animal; Cell Proliferation; Cognition; Cognitive Dysfunction; Disease Models, Animal; Dopaminergic Neurons; Hippocampus; Inflammation Mediators; Male; Maneb; Maze Learning; Mice, Inbred C57BL; Microglia; Nerve Degeneration; Paraquat; Parkinsonian Disorders; Pars Compacta; Phagocytosis; Poloxamer; Recognition, Psychology; Synapses	2020
Integrin CD11b mediates locus coeruleus noradrenergic neurodegeneration in a mouse Parkinson's disease model. Journal of neuroinflammation, 2020, May-06, Volume: 17, Issue:1 Topics: Adrenergic Neurons; Animals; CD11b Antigen; Disease Models, Animal; Inflammasomes; Locus Coeruleus; Male; Maneb; Mice; Mice, Inbred C57BL; Mice, Knockout; Microglia; Nerve Degeneration; NLR Family, Pyrin Domain-Containing 3 Protein; Paraquat; Parkinsonian Disorders; Pesticides	2020
Inhibition of NLRP3 inflammasome by glibenclamide attenuated dopaminergic neurodegeneration and motor deficits in paraquat and maneb-induced mouse Parkinson's disease model. Toxicology letters, 2021, Oct-01, Volume: 349 Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Antiparkinson Agents; Disease Models, Animal; Dopaminergic Neurons; Glyburide; Inflammasomes; Lipid Peroxidation; Male; Maneb; Mice, Inbred C57BL; Microglia; Motor Activity; NADPH Oxidase 2; Nerve Degeneration; Neuroprotective Agents; NF-kappa B; Nitric Oxide Synthase Type II; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Paraquat; Parkinsonian Disorders	2021
Mutations in Caenorhabditis elegans neuroligin-like glit-1, the apoptosis pathway and the calcium chaperone crt-1 increase dopaminergic neurodegeneration after 6-OHDA treatment. PLoS genetics, 2018, Volume: 14, Issue:1 Topics: Animals; Animals, Genetically Modified; Apoptosis; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Calcium; Calreticulin; Dopaminergic Neurons; Hydrogen Peroxide; Membrane Proteins; Molecular Chaperones; Mutation; Nerve Degeneration; Nerve Tissue Proteins; Oxidants; Oxidative Stress; Oxidopamine; Paraquat	2018
6-OHDA-induced dopaminergic neurodegeneration in Caenorhabditis elegans is promoted by the engulfment pathway and inhibited by the transthyretin-related protein TTR-33. PLoS genetics, 2018, Volume: 14, Issue:1 Topics: Animals; Animals, Genetically Modified; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Carrier Proteins; Dopaminergic Neurons; Hydrogen Peroxide; Intercellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; Mutation; Nerve Degeneration; Oxidants; Oxidative Stress; Oxidopamine; Paraquat; Signal Transduction	2018
Blockade of Rapid Influx of Extracellular Zn Molecular neurobiology, 2019, Volume: 56, Issue:6 Topics: Animals; Behavior, Animal; Chelating Agents; Dopaminergic Neurons; Extracellular Space; Glutamic Acid; Male; Models, Biological; Movement Disorders; Nerve Degeneration; Paraquat; Parkinson Disease; Rats, Wistar; Reactive Oxygen Species; Substantia Nigra; Zinc	2019
NADPH oxidase regulates paraquat and maneb-induced dopaminergic neurodegeneration through ferroptosis. Toxicology, 2019, 04-01, Volume: 417 Topics: Animals; Cell Line, Tumor; Dopaminergic Neurons; Ferroptosis; Fungicides, Industrial; Herbicides; Humans; Male; Maneb; Mice; Mice, Inbred C57BL; NADPH Oxidases; Nerve Degeneration; Paraquat; Random Allocation	2019
Pharmacokinetic, neurochemical, stereological and neuropathological studies on the potential effects of paraquat in the substantia nigra pars compacta and striatum of male C57BL/6J mice. Neurotoxicology, 2013, Volume: 37 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Astrocytes; Basal Ganglia; Cell Death; Dopamine; Dopaminergic Neurons; Dose-Response Relationship, Drug; Drug Administration Schedule; Half-Life; Herbicides; Homovanillic Acid; Injections, Intraperitoneal; Male; Metabolic Clearance Rate; Mice; Mice, Inbred C57BL; Microglia; MPTP Poisoning; Nerve Degeneration; Paraquat; Substantia Nigra; Tyrosine 3-Monooxygenase	2013
Mutation in Drosophila methuselah resists paraquat induced Parkinson-like phenotypes. Neurobiology of aging, 2014, Volume: 35, Issue:10 Topics: Aging; Animals; Apoptosis; Caspase 3; Dopamine; Dopaminergic Neurons; Drosophila; Drosophila Proteins; Forkhead Transcription Factors; Herbicide Resistance; Herbicides; Male; MAP Kinase Kinase 4; Motor Activity; Mutation; Nerve Degeneration; Neuropeptides; Oxidative Stress; Paraquat; Parkinson Disease, Secondary; Phenotype; Receptors, G-Protein-Coupled	2014
Metabolomic Analysis Provides Insights on Paraquat-Induced Parkinson-Like Symptoms in Drosophila melanogaster. Molecular neurobiology, 2016, Volume: 53, Issue:1 Topics: Animals; Behavior, Animal; Brain; Drosophila melanogaster; Gas Chromatography-Mass Spectrometry; Metabolic Networks and Pathways; Metabolome; Metabolomics; Motor Activity; Nerve Degeneration; Oxidative Stress; Paraquat; Parkinson Disease; Principal Component Analysis; Reproducibility of Results	2016
Exposure to mitochondrial genotoxins and dopaminergic neurodegeneration in Caenorhabditis elegans. PloS one, 2014, Volume: 9, Issue:12 Topics: Adrenergic Agents; Animals; Caenorhabditis elegans; DNA Damage; DNA, Mitochondrial; Dopamine; Dopamine Agents; Dopaminergic Neurons; Mitochondria; Mutagens; Nerve Degeneration; Oxidopamine; Paraquat	2014
Antioxidant and neuroprotective effects of Dictyophora indusiata polysaccharide in Caenorhabditis elegans. Journal of ethnopharmacology, 2016, Nov-04, Volume: 192 Topics: Adenosine Triphosphate; Agaricales; Amyloid beta-Peptides; Animals; Animals, Genetically Modified; Antioxidants; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Dose-Response Relationship, Drug; Energy Metabolism; Malondialdehyde; Membrane Potential, Mitochondrial; Mitochondria; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Oxidative Stress; Paraquat; Peptides; Polysaccharides; Reactive Oxygen Species; Superoxide Dismutase; Time Factors	2016
Paraquat and maneb co-exposure induces noradrenergic locus coeruleus neurodegeneration through NADPH oxidase-mediated microglial activation. Toxicology, 2017, 04-01, Volume: 380 Topics: Acetophenones; Adrenergic Neurons; Animals; Disease Models, Animal; Enzyme Inhibitors; Locus Coeruleus; Male; Maneb; Mice; Mice, Inbred C57BL; Microglia; NADPH Oxidases; Nerve Degeneration; Neurotoxicity Syndromes; NF-kappa B; Paraquat; Parkinson Disease; Risk Factors	2017
Oxidative stress induced by loss of Cu,Zn-superoxide dismutase (SOD1) or superoxide-generating herbicides causes axonal degeneration in mouse DRG cultures. Acta neuropathologica, 2010, Volume: 119, Issue:2 Topics: Animals; Axons; Cells, Cultured; Diquat; Ganglia, Spinal; Herbicides; Humans; Mice; Mice, Transgenic; Nerve Degeneration; Oxidative Stress; Paraquat; Superoxide Dismutase; Superoxide Dismutase-1; Superoxides	2010
Caffeine protects against combined paraquat and maneb-induced dopaminergic neuron degeneration. Experimental neurology, 2010, Volume: 223, Issue:2 Topics: Animals; Caffeine; Cell Count; Chronic Disease; Disease Models, Animal; Dopamine; Drug Interactions; Fungicides, Industrial; Herbicides; Locomotion; Male; Maneb; Mice; Mice, Inbred C57BL; Nerve Degeneration; Neurons; Neuroprotective Agents; Paraquat; Substantia Nigra	2010
Effect of zinc and paraquat co-exposure on neurodegeneration: Modulation of oxidative stress and expression of metallothioneins, toxicant responsive and transporter genes in rats. Free radical research, 2010, Volume: 44, Issue:8 Topics: Animals; Blotting, Western; Cytochrome P-450 CYP2E1; Dopamine Plasma Membrane Transport Proteins; Glutathione Transferase; Male; Metallothionein; Motor Activity; Nerve Degeneration; Oxidative Stress; Paraquat; Rats; Rats, Wistar; Tissue Distribution; Vesicular Monoamine Transport Proteins; Zinc	2010
Synergistic effects of environmental risk factors and gene mutations in Parkinson's disease accelerate age-related neurodegeneration. Journal of neurochemistry, 2010, Volume: 115, Issue:6 Topics: Aging; alpha-Synuclein; Animals; Cell Line; Cells, Cultured; Disease Progression; Environmental Exposure; Humans; Iron; Mice; Mice, Transgenic; Mutation; Nerve Degeneration; Paraquat; Parkinson Disease; Rats; Risk Factors	2010
The role of calcium channel blockers and resveratrol in the prevention of paraquat-induced parkinsonism in Drosophila melanogaster: a locomotor analysis. Invertebrate neuroscience : IN, 2011, Volume: 11, Issue:1 Topics: Animals; Antioxidants; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Disease Models, Animal; Dopamine; Drosophila melanogaster; Nerve Degeneration; Paraquat; Parkinsonian Disorders; Resveratrol; Stilbenes; Substantia Nigra	2011
Traumatic brain injury in adult rats causes progressive nigrostriatal dopaminergic cell loss and enhanced vulnerability to the pesticide paraquat. Journal of neurotrauma, 2011, Volume: 28, Issue:9 Topics: Animals; Brain Injuries; Cell Death; Corpus Striatum; Dopamine; Herbicides; Male; Nerve Degeneration; Neurons; Paraquat; Rats; Rats, Sprague-Dawley; Substantia Nigra; Tyrosine 3-Monooxygenase	2011
Paraquat induces epigenetic changes by promoting histone acetylation in cell culture models of dopaminergic degeneration. Neurotoxicology, 2011, Volume: 32, Issue:5 Topics: Acetylation; Animals; Cell Culture Techniques; Cells, Cultured; Dopaminergic Neurons; Epigenesis, Genetic; Female; Histone Deacetylases; Histones; Mice; Mice, Inbred C57BL; Nerve Degeneration; Paraquat; Pregnancy; Rats	2011
Differential regional expression patterns of α-synuclein, TNF-α, and IL-1β; and variable status of dopaminergic neurotoxicity in mouse brain after Paraquat treatment. Journal of neuroinflammation, 2011, Nov-24, Volume: 8 Topics: alpha-Synuclein; alpha-Tocopherol; Animals; Antioxidants; Behavior, Animal; Catalase; DNA-Binding Proteins; Dopaminergic Neurons; Dose-Response Relationship, Drug; Frontal Lobe; Glutathione Transferase; Herbicides; Hippocampus; Humans; Interleukin-1beta; Male; Mice; Nerve Degeneration; Nerve Tissue Proteins; Nuclear Proteins; Paraquat; Random Allocation; Reactive Oxygen Species; Substantia Nigra; Superoxide Dismutase; Survival Rate; Tumor Necrosis Factor-alpha; Tyrosine 3-Monooxygenase	2011
Glutathione s-transferase omega 1 activity is sufficient to suppress neurodegeneration in a Drosophila model of Parkinson disease. The Journal of biological chemistry, 2012, Feb-24, Volume: 287, Issue:9 Topics: Animals; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins; Glutathione Transferase; Herbicides; JNK Mitogen-Activated Protein Kinases; Male; Mitochondrial Proton-Translocating ATPases; Mutagenesis, Site-Directed; Nerve Degeneration; Oxidative Stress; Paraquat; Parkinsonian Disorders; Phenotype; Signal Transduction; Tubulin; Ubiquitin-Protein Ligases; Unfolded Protein Response	2012
Genetic dissection of strain dependent paraquat-induced neurodegeneration in the substantia nigra pars compacta. PloS one, 2012, Volume: 7, Issue:1 Topics: Animals; Dopaminergic Neurons; Female; Gene Expression Profiling; Genetic Association Studies; Genetic Predisposition to Disease; Herbicides; Male; Mice; Mice, Inbred C57BL; Microarray Analysis; Nerve Degeneration; Paraquat; Species Specificity; Substantia Nigra	2012
Viral-toxin interactions and Parkinson's disease: poly I:C priming enhanced the neurodegenerative effects of paraquat. Journal of neuroinflammation, 2012, May-04, Volume: 9 Topics: Animals; Antiviral Agents; Corpus Striatum; Disease Models, Animal; Drug Synergism; Male; Mice; Mice, Inbred C57BL; Nerve Degeneration; Paraquat; Parkinsonian Disorders; Poly I-C	2012
Black rice extract extends the lifespan of fruit flies. Food & function, 2012, Volume: 3, Issue:12 Topics: Animals; Animals, Genetically Modified; Antioxidants; Catalase; Diet; Drosophila melanogaster; Drosophila Proteins; Endopeptidases; Gene Expression Regulation; Longevity; Nerve Degeneration; Oryza; Oxidative Stress; Paraquat; Plant Extracts; Seeds; Superoxide Dismutase; Superoxide Dismutase-1	2012
Environmental risk factors and Parkinson's disease: selective degeneration of nigral dopaminergic neurons caused by the herbicide paraquat. Neurobiology of disease, 2002, Volume: 10, Issue:2 Topics: 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Biomarkers; Dopamine; Environmental Exposure; gamma-Aminobutyric Acid; Gliosis; Herbicides; Homovanillic Acid; Humans; Injections, Intraperitoneal; Male; Mesencephalon; Mice; Mice, Inbred C57BL; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Paraquat; Parkinson Disease; Parkinson Disease, Secondary; Parkinsonian Disorders; Risk Factors; Substantia Nigra; Tyrosine 3-Monooxygenase	2002
Synergistic effects of low level stressors in an oxidative damage model of spinal motor neuron degeneration. Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases, 2002, Volume: 3, Issue:3 Topics: Animals; Cell Death; Cells, Cultured; Dose-Response Relationship, Drug; Drug Synergism; Embryo, Mammalian; Ganglia, Spinal; Glutamic Acid; Heating; Mice; Motor Neurons; Nerve Degeneration; Oxidation-Reduction; Oxidative Stress; Paraquat; Receptors, Kainic Acid; Spinal Cord	2002
Decreasing glutamate buffering capacity triggers oxidative stress and neuropil degeneration in the Drosophila brain. Current biology : CB, 2004, Apr-06, Volume: 14, Issue:7 Topics: Animals; Brain; DNA Primers; Drosophila; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Fluorescence; Gene Silencing; Glutamic Acid; Humans; Melatonin; Microscopy, Electron, Scanning; Movement; Nerve Degeneration; Neuropil; Oxidative Stress; Paraquat; Reverse Transcriptase Polymerase Chain Reaction; Riluzole; RNA Interference	2004
Role of oxidative stress in paraquat-induced dopaminergic cell degeneration. Journal of neurochemistry, 2005, Volume: 93, Issue:4 Topics: Aldehydes; Analysis of Variance; Animals; Cell Count; Dopamine; Drug Administration Schedule; Ferritins; Herbicides; Humans; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Degeneration; Oxidative Stress; Paraquat; Promoter Regions, Genetic; Time Factors; Tyrosine; Tyrosine 3-Monooxygenase	2005
Neuroprotective effects of Polygonum multiflorum on nigrostriatal dopaminergic degeneration induced by paraquat and maneb in mice. Pharmacology, biochemistry, and behavior, 2005, Volume: 82, Issue:2 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antiparkinson Agents; Chromatography, High Pressure Liquid; Dopamine; Fungicides, Industrial; Herbicides; Immunohistochemistry; Levodopa; Male; Maneb; Mice; Mice, Inbred C57BL; Motor Activity; Neostriatum; Nerve Degeneration; Neuroprotective Agents; Paraquat; Parkinson Disease, Secondary; Phytotherapy; Plant Roots; Polygonum; Substantia Nigra; Tyrosine 3-Monooxygenase	2005
Systemic exposure to paraquat and maneb models early Parkinson's disease in young adult rats. Neurobiology of disease, 2005, Volume: 20, Issue:2 Topics: Age of Onset; Animals; Cells, Cultured; Coculture Techniques; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Encephalitis; Fungicides, Industrial; Gliosis; Herbicides; Male; Maneb; Microglia; Nerve Degeneration; Neurons; Paraquat; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Rats, Wistar; Substantia Nigra	2005
Decreased susceptibility to oxidative stress underlies the resistance of specific dopaminergic cell populations to paraquat-induced degeneration. Neuroscience, 2006, Aug-25, Volume: 141, Issue:2 Topics: Aldehydes; Analysis of Variance; Animals; Calbindin 1; Calbindins; Cell Count; Dopamine; Herbicides; Immunohistochemistry; Male; Mesencephalon; Mice; Nerve Degeneration; Neurons; Oxidative Stress; Paraquat; S100 Calcium Binding Protein G; Time Factors; Tyrosine 3-Monooxygenase	2006
Transduced Tat-alpha-synuclein protects against oxidative stress in vitro and in vivo. Journal of biochemistry and molecular biology, 2006, May-31, Volume: 39, Issue:3 Topics: alpha-Synuclein; Animals; Astrocytes; Cell Death; Cell Survival; Gene Products, tat; Genetic Vectors; HSP70 Heat-Shock Proteins; Humans; Male; Mice; Mice, Inbred C57BL; Mutation; Nerve Degeneration; Neurons; Oxidative Stress; Paraquat; Parkinsonian Disorders; Protein Transport; Recombinant Fusion Proteins; Transduction, Genetic	2006
Degeneration of dopaminergic mesocortical neurons and activation of compensatory processes induced by a long-term paraquat administration in rats: implications for Parkinson's disease. Neuroscience, 2006, Sep-15, Volume: 141, Issue:4 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Cerebral Cortex; Chromatography, High Pressure Liquid; Disease Models, Animal; Dopamine; Herbicides; Homovanillic Acid; Immunohistochemistry; Male; Nerve Degeneration; Neurons; Paraquat; Parkinsonian Disorders; Rats; Rats, Wistar; Tyrosine 3-Monooxygenase; Ventral Tegmental Area	2006
Temporal effects of paraquat/maneb on microglial activation and dopamine neuronal loss in older rats. Journal of neurochemistry, 2006, Volume: 98, Issue:3 Topics: Aging; Animals; Cell Death; Dopamine; Drug Administration Schedule; Drug Combinations; Male; Maneb; Microglia; Nerve Degeneration; Neurons; Paraquat; Rats; Rats, Sprague-Dawley; Time Factors	2006
Mitochondrial damage modulates alternative splicing in neuronal cells: implications for neurodegeneration. Journal of neurochemistry, 2007, Volume: 100, Issue:1 Topics: Adenosine Triphosphate; Alternative Splicing; Cell Line; Cycloheximide; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression Regulation; Glioma; Humans; Mitochondria; Nerve Degeneration; Neuroblastoma; Neurons; Neurotoxins; Paraquat; Protein Synthesis Inhibitors; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors	2007
Microglial activation as a priming event leading to paraquat-induced dopaminergic cell degeneration. Neurobiology of disease, 2007, Volume: 25, Issue:2 Topics: Animals; Anti-Inflammatory Agents; Biomarkers; Dopamine; Encephalitis; Gliosis; Herbicides; Inflammation Mediators; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Microglia; Minocycline; NADPH Oxidases; Nerve Degeneration; Neurotoxins; Oxidative Stress; Paraquat; Parkinsonian Disorders; Substantia Nigra	2007
Oxidative stress mediates tau-induced neurodegeneration in Drosophila. The Journal of clinical investigation, 2007, Volume: 117, Issue:1 Topics: Alzheimer Disease; Animals; Disease Models, Animal; Drosophila; Humans; Nerve Degeneration; Oxidative Stress; Paraquat; tau Proteins; Tauopathies; Vitamin E	2007
Toxic influence of subchronic paraquat administration on dopaminergic neurons in rats. Brain research, 2007, Jun-25, Volume: 1155 Topics: Animals; Caudate Nucleus; Dopamine; Drug Administration Schedule; Gene Expression Regulation, Enzymologic; Glutamate Decarboxylase; Herbicides; Isoenzymes; Nerve Degeneration; Neurons; Paraquat; Parkinsonian Disorders; Putamen; Rats; RNA, Messenger	2007
Iron and paraquat as synergistic environmental risk factors in sporadic Parkinson's disease accelerate age-related neurodegeneration. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Jun-27, Volume: 27, Issue:26 Topics: Aging; Animals; Cell Line; Cells, Cultured; Drug Synergism; Environmental Exposure; Herbicides; Iron; Male; Mice; Mice, Inbred C57BL; Nerve Degeneration; Neurons; Neuroprotective Agents; Organometallic Compounds; Paraquat; Parkinson Disease; Rats; Salicylates; Substantia Nigra; Superoxide Dismutase	2007
Cytotoxicity of paraquat in microglial cells: Involvement of PKCdelta- and ERK1/2-dependent NADPH oxidase. Brain research, 2007, Sep-05, Volume: 1167 Topics: Animals; Brain; Cell Line; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Herbicides; Mice; Microglia; NADPH Oxidases; Nerve Degeneration; Neurotoxins; Oxidative Stress; Paraquat; Parkinson Disease; Phosphoproteins; Protein Kinase C-delta; Protein Transport; Reactive Oxygen Species; Signal Transduction	2007
Chronic inhalation of rotenone or paraquat does not induce Parkinson's disease symptoms in mice or rats. Experimental neurology, 2007, Volume: 208, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Administration, Inhalation; Administration, Intranasal; Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Drug Administration Schedule; Herbicides; Insecticides; Male; Mice; Mice, Inbred C57BL; Motor Activity; Nerve Degeneration; Neurons; Paraquat; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Rotenone; Substantia Nigra	2007
Inflammatory priming of the substantia nigra influences the impact of later paraquat exposure: Neuroimmune sensitization of neurodegeneration. Neurobiology of aging, 2009, Volume: 30, Issue:9 Topics: Animals; Cytokines; Drug Administration Schedule; Drug Interactions; Drug Synergism; Encephalitis; Hazardous Substances; Herbicides; Inflammation Mediators; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Microglia; Nerve Degeneration; Neuroimmunomodulation; Paraquat; Parkinsonian Disorders; Substantia Nigra	2009
Neurodegeneration produced by intrahippocampal injection of paraquat is reduced by systemic administration of the 21-aminosteroid U74389F in rats. Free radical research, 1994, Volume: 21, Issue:2 Topics: Animals; Antioxidants; Free Radicals; Hippocampus; Male; Motor Activity; Nerve Degeneration; Nervous System Diseases; Paraquat; Pregnatrienes; Rats; Rats, Wistar; Seizures	1994
Motor neuron degeneration is attenuated in bax-deficient neurons in vitro. Journal of neuroscience research, 1999, Mar-01, Volume: 55, Issue:5 Topics: Animals; Aspartic Acid; Astrocytes; bcl-2-Associated X Protein; Cell Death; Cell Division; Cell Nucleus; Cell Size; Cell Survival; Cells, Cultured; Culture Media, Serum-Free; Female; Genotype; Kainic Acid; Male; Mice; Motor Neurons; Nerve Degeneration; Paraquat; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Spinal Cord; Superoxides	1999
Dependence of excitotoxic neurodegeneration on mitochondrial aconitase inactivation. Journal of neurochemistry, 2001, Volume: 78, Issue:4 Topics: Aconitate Hydratase; Animals; Astrocytes; Cell Death; Cell Fractionation; Cells, Cultured; Enzyme Inhibitors; Fumarate Hydratase; Glucose; Kainic Acid; Metalloporphyrins; Mitochondria; N-Methylaspartate; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Oxygen; Paraquat; Rats; Superoxides	2001