paraquat has been researched along with Disease Models, Animal in 248 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (9.27) | 18.7374 |
| 1990's | 8 (3.23) | 18.2507 |
| 2000's | 57 (22.98) | 29.6817 |
| 2010's | 126 (50.81) | 24.3611 |
| 2020's | 34 (13.71) | 2.80 |
| Authors | Studies |
|---|---|
| Dai, Z; Ding, Y; Hu, Y; Hua, H; Li, J; Li, Q; Li, T; Qian, C; Sun, H; Wang, J; Yang, X; Zhang, W | 1 |
| Ahmad, MH; Ali, M; Fatima, M; Mondal, AC; Rizvi, MA | 1 |
| Kuter, KZ; Ossowska, K; Śmiałowska, M | 1 |
| Arsac, JN; Baron, T; Dartiguelongue, M; Davoust, N; Mollereau, B; Sedru, M; Vulin, J | 1 |
| Huang, M; Li, G; Shi, G; Tian, T; Wang, K; Zhang, B; Zhang, C | 1 |
| Chen, H; Cui, J; Gong, Y; Liu, L; Ma, Y; Tian, Y; Tong, F; Wang, J; Wang, Y; Zhang, X | 1 |
| Agarwal, S; Chang, YM; Desai, TD; Ho, TJ; Huang, CY; Ju, DT; Kuo, WW; Liao, SC; Lin, YJ; Sun, JM; Yeh, YL | 1 |
| Cai, Q; Huang, M; Li, G; Shi, G; Wang, K; Zhang, B; Zhang, C | 1 |
| Chang, R; Hou, L; Huang, R; Liu, J; Ruan, Z; Sun, F; Wang, Q; Wang, Y; Zhao, J | 1 |
| Bernardino, L; Cristóvão, AC; Esteves, M; Ferreira, R; Lopes-Nunes, J; Santos, T; Saraiva, C; Vale, A | 1 |
| Cheng, B; Geng, L; Li, R; Lou, X; Lu, K; Song, W; Wang, L; Zhang, S | 1 |
| Alenabi, A; Hallaj-Salahipour, M; Khoramjouy, M; Malekinejad, H; Malekinejad, M; Masoumi Verki, M | 1 |
| Chen, YJ; Lin, NC; Yang, CH; Yeh, AI; Yeh, PT | 1 |
| Alves, G; Beal, MF; Bernardino, L; Campos, FL; Cristóvão, AC; Esteves, M; Fonseca, BM; Guhathakurta, S; Je, G; Kim, YS; Queiroz, J; Salgado, AJ; Sousa, N; Yang, L; Yoon, KS | 1 |
| Chauhan, AK; Mittra, N; Patel, DK; Singh, C; Singh, G | 1 |
| Ding, W; Hong, X; Ji, D; Lin, H; Wu, F | 1 |
| Hou, L; Huang, R; Qiu, X; Qu, X; Wang, Q; Zhao, X | 1 |
| Ambaryan, A; Danilenko, V; Marsova, M; Odorskaya, M; Pavlova, G; Poluektova, E; Revishchin, A | 1 |
| Freeman, JL; Wasel, O | 1 |
| Ahmad, B; Akhtar, MF; Anwar, F; Ismail, T; Nazir, S; Saleem, U; Sanawar, M | 1 |
| Bhattacharyya, A; Chatterjee, S; Dalui, S; Sinha, P | 1 |
| Cui, Y; Mei, L; Tao, Y; Wang, Z; Xin, H | 1 |
| Fu, Y; Lin, Z; Zhang, W; Zheng, F; Zhu, J | 1 |
| Cai, P; Guo, Z; Huang, S; Li, H; Luo, Z; Shao, W; Wang, YL; Wu, J; Wu, S; Yang, H; Zhang, Y; Zheng, F | 1 |
| Chen, YB; Cui, YL; Wang, YQ; Wu, JR | 1 |
| Ayoub, K; Beauchamp, S; Derksen, A; Dwyer, Z; Farmer, K; Fortin, T; Hayley, S; Rudyk, C; Shail, P; Torres, C; Ventura, K | 1 |
| Deng, G; Li, L; Ouyang, Y | 1 |
| Ciesla, L; Harding, T; Liang, Q; Maitra, U | 1 |
| Baetu, I; Collins-Praino, LE; El-Gamal, M; Fathalla, AM; Mohamed, W; Moustafa, AA; Salama, M; Soliman, AM | 1 |
| Chen, Z; Jiang, F; Jiang, Y; Li, S; Liu, W; Wang, T | 1 |
| Amin, F; Boskabady, MH; Kazerani, HR; Memarzia, A; Rad, HK | 1 |
| El-Dash, HA; Fathy, SM; Said, NI | 1 |
| Hou, L; Qiu, X; Wang, Q; Zhang, C; Zhao, X | 1 |
| Amin, F; Boskabady, MH; Kazemi Rad, H; Memarzia, A; Shakeri, F | 1 |
| Chang, Y; Gao, G; Li, X; Li, Y; Shi, Z; Thirupathi, A; Xie, J; Yu, P; Zhang, J; Zuo, Y | 1 |
| Chen, F; Wang, X; Xing, J; Xu, L; Yan, B | 1 |
| Hu, X; Shen, H; Wang, Y; Zhao, M | 1 |
| Mandegary, A; Pardakhty, A; Rajaian, H; Rasooli, R | 1 |
| Attia, HN; Maklad, YA | 1 |
| Anselmi, L; Bove, C; Hampton, J; Toti, L; Travagli, RA | 1 |
| Kamali, Y; Mandegary, A; Nabipour, F; Pourgholamhosein, F; Rasooli, R | 1 |
| Dong, XS; Liu, W; Liu, Z; Song, HW; Yang, C | 1 |
| Chen, H; Chen, Q; Fu, Z; Jiang, CM; Li, ZY; Li, ZZ; Liu, L; Shi, GY; Su, YM; Sui, BW; Sun, HQ; Yang, LZ; Zhang, W; Zhao, WC | 1 |
| Feng, Q; Wang, T; Zhang, L | 1 |
| Connor, JR; Huang, X; Lamendella, R; Meadowcroft, MD; Nandar, W; Neely, EB; Nixon, AM; Purnell, CJ; Snyder, AM; Wright, J | 1 |
| Chen, W; Li, CQ; Lin, H; Xiang, L; Yang, X; Zhang, JF; Zhang, JH | 1 |
| Li, A; Lu, M; Wang, R; Wen, Y; Xu, J; Zhao, X; Zhou, J | 1 |
| Feng, S; He, F; Li, Y; Liu, T; Zhou, A | 1 |
| Che, Y; Hou, L; Li, H; Liu, X; Piao, F; Sun, F; Wang, Q; Zhang, C; Zhang, D | 1 |
| S, N; Shivanandappa, T | 1 |
| Jimenez-Del-Rio, M; Martinez-Perez, DA; Velez-Pardo, C | 1 |
| Chen, F; Fan, H; Hu, L; Huang, H; Lou, J; Yu, Y; Zhu, W | 1 |
| Koike, M; Masuda, I; Mizutani, Y; Nakashima, S; Nojiri, H; Ozawa, Y; Sashihara, K; Sawada, Y; Shimizu, T; Sugimoto, A; Sugiyama, H; Watanabe, K; Yokote, K | 1 |
| Feng, S; Gao, J; Li, Y | 1 |
| Bastías-Candia, S; Inestrosa, NC; Zolezzi, JM | 1 |
| Chen, J; Li, Z; Liu, M; Niu, W; Sun, X; Wang, Y; Wu, H | 1 |
| Lu, J; Meng, X; Wang, R; Xie, H; Zhu, Y | 1 |
| He, D; Lei, L; Liu, M; Lou, D; Lu, S; Shi, Y; Song, Y; Wang, Z; Wu, S | 1 |
| Bian, Z; Chen, J; Feng, N; Wang, C; Zhang, X | 1 |
| Cao, Z; Gao, L; Liu, J; Xu, E; Yuan, H | 1 |
| Brandt, A; Joop, G; Vilcinskas, A | 1 |
| Birman, S; Cassar, M; Hajji, K; Leprince, J; Masmoudi-Kouki, O; Mezghani, S; Mteyrek, A; Sun, J; Vaudry, D | 1 |
| Antonucci, S; Burger, N; Caldwell, ST; Deshwal, S; Di Lisa, F; Di Sante, M; Gruszczyk, AV; Hall, AR; Hartley, RC; Hinchy, EC; Kaludercic, N; Krieg, T; Mulvey, JF; Murphy, MP | 1 |
| Chen, J; Deng, Y; Si, L; Zhou, L | 1 |
| Ding, G; Jiang, C; Ma, S; Wang, X; Xiao, W; Zhang, J; Zhong, R | 1 |
| AlAjmi, MF; El-Aarag, B; El-Seedi, HR; Khalifa, SAM; Magdy, M | 1 |
| Anselmi, L; Bove, C; Travagli, RA | 1 |
| Chang, X; Shao, Y; Zhang, F; Zhang, Y; Zhao, Y; Zhou, Z; Zhu, T | 1 |
| Chouhan, S; Prakash, J; Singh, SP; Yadav, SK | 2 |
| Abad, C; Bala, N; Chesselet, MF; Lee, SK; Nobuta, H; Richter, F; Waschek, JA; Watson, MB; Zhu, C | 1 |
| Chang, ZJ; Li, D; Lu, ZQ; Nan, C; Xu, LY; Zhao, GJ | 1 |
| Dixit, A; Mishra, M; Prakash, O; Singh, MP; Singh, PK; Srivastava, G; Verma, D | 1 |
| Chang, XL; Huang, M; Yang, HF; Zhang, P; Zhou, ZJ | 1 |
| Choi, JS; Gil, HW; Hong, SY; Jou, SS; Kim, YH; Oh, MH; Park, MJ; Song, HY | 1 |
| Chauhan, AK; Jain, SK; Shanker, R; Singh, C; Singh, MP; Singhal, NK | 1 |
| Jian, X; Wang, J; Zhang, W; Zhang, Z; Zhou, Q | 1 |
| Borges, EL; Caliari, MV; da Glória Rodrigues-Machado, M; de Barros Pinheiro, M; Prata, LO; Rodrigues-Machado, MG; Sales, WA; Silva, YA | 1 |
| Armstrong, SM; Moore, C; Willis, GL | 1 |
| Allen, JL; Conrad, K; Cory-Slechta, DA; Liu, X; Oberdörster, G; Weston, D | 1 |
| Ettle, B; Fields, J; Kosberg, K; Mante, M; Masliah, E; Nuber, S; Overk, CR; Rockenstein, E; Tadros, D; Trejo, M | 1 |
| Crouch, PJ; Hannan, AJ; Hilton, JB; Hung, LW; Li, QX; Liddell, JR; Lim, NK; Mclean, CA; Pang, TY; White, AR | 1 |
| Kachroo, A; Schwarzschild, MA | 1 |
| Abdin, MZ; Chaouhan, HS; Chowdhuri, DK; Patel, DK; Pragya, P; Shukla, AK; Tiwari, AK | 1 |
| Lv, L; Qian, J; Ye, S; Ye, Y; Zhu, C | 1 |
| Dong, Y; Li, X; Peng, L; Zhang, Z | 1 |
| Che, L; Di, M; Lan, C; Li, H; Li, L; Liu, L; Su, Q; Wang, J | 2 |
| Gong, J; Hu, M; Li, Y; Wu, W | 1 |
| Chen, X; Han, W; Hong, G; Li, D; Lu, Z; Wang, L | 1 |
| Xu, J; Zheng, J; Zhu, J | 1 |
| Aleksunes, LM; Buckley, B; Gibson, CJ; Goedken, MJ; Richardson, JR; Wen, X; Yang, I | 1 |
| Chiou, SH; Fang, IM; Yang, CH; Yang, CM | 1 |
| Birman, S; Cassar, M; Coulom, H; Han, KA; Iché-Torres, M; Issa, AR; Petitgas, C; Riemensperger, T; Rival, T | 1 |
| Assani, K; Barajas, A; Krantz, DE; Lawal, HO; Lawless, G; Lumintang, YP; Martin, CA; Nunez, V | 1 |
| Han, W; Hong, G; Liu, H; Lu, Y; Lu, Z; Qiu, Q; Wang, L; Wu, D | 1 |
| Achumi, B; Alone, DP; Phom, L; Yenisetti, SC | 1 |
| Chen, D; Jiao, G; Liu, X; Liu, Z; Ma, T; Yang, C | 1 |
| Chen, JH; Feng, S; Jiang, H; Lang, XB; Li, H; Li, M; Lin, C; Lu, YY; Luo, C; Shao, X; Shen, XJ; Wang, YC; Wang, YY; Zhou, Q | 1 |
| Cai, X; Hong, G; Li, D; Li, M; Lu, Z; She, X; Wu, B; Zhao, G | 1 |
| Cappelletti, L; Dallemole, DR; Ellwanger, JH; Franke, SI; Gonçalves da Silva, M; Molz, P; Müller, TE; Pêgas Henriques, JA; Pereira dos Santos, A; Prá, D | 1 |
| Dou, Y; Jay Smeyne, R; Jiao, Y; Lockwood, G; Pani, A | 1 |
| Ding, L; Huang, X; Wu, L; Xu, L; Zhang, Z; Zheng, L | 1 |
| Morrison, BE; Stojkovska, I; Wagner, BM | 1 |
| Corbett, J; Kadiiska, MB; Kumar, A; Leinisch, F; Mason, RP | 1 |
| Gao, B; Hu, N; Li, N; Liu, M; Lu, S; Wang, H; Wang, J; Yu, W; Zhang, G; Zhang, Y; Zheng, Q | 1 |
| Boldt, E; Chen, L; Na, R; Ran, Q | 1 |
| Chen, D; Liu, XW; Liu, Z; Ma, T; Yang, C | 1 |
| Chang, WX; Han, YY; Shen, P | 1 |
| Rajini, PS; Rao, SV; Yenisetti, SC | 1 |
| Akcılar, A; Akcılar, R; Bayat, Z; Koçak, C; Koçak, FE; Şimşek, H; Yümün, G | 1 |
| Dong, MN; Li, YY; Liu, MW; Liu, R; Qian, CY; Su, MX; Wu, HY; Zhang, W | 1 |
| Deyun, C; Jie, Z; Qiaoli, S; Yi, S | 1 |
| Chen, J; Chen, W; Jiang, L; Kang, J; Qian, W; Qiao, L; Sun, H; Wang, J; Zhang, J | 1 |
| Thompson, M; Xu, YH; Zhang, XF | 1 |
| Gu, SY; Lin, SY; Peng, FC; Yeh, TY | 1 |
| Ottesen, EW; Seo, J; Shishimorova, M; Singh, NN; Singh, RN; Sivanesan, S | 1 |
| Altinel, O; Altinel, S; Ates, K; Istanbulluoglu, H; Karslioglu, Y; Korkmaz, A; Ogur, R; Topal, T; Toygar, M; Tuncer, SK; Uysal, B | 1 |
| Dash, D; Singh, R; Tyagi, N | 1 |
| Borderie, D; Charbonnier, F; Eid, AA; Gorgievski, V; Grenier, J; Hichor, M; Massaad, C; Montanaro, J; Petit, PX; Sampathkumar, NK; Tzavara, ET | 1 |
| Ackerson, LC; Cely, I; Chesselet, MF; De La Rosa, K; Gabby, L; Maidment, NT; McDowell, KA; Mortazavi, F; Mulligan, CK; Murphy, NP; Richter, F; Sioshansi, PC; Tsan, L | 1 |
| Gan, SH; Jaafar, H; Kuttulebbai Nainamohamed Salam, S; Muzaimi, M; Sulaiman, SA; Tang, SP | 1 |
| Christian, PK; Guruprasad, BR; Kumar, A; Panchal, K; Tiwari, AK | 1 |
| Che, Y; Hou, L; Liu, X; Sun, F; Wang, H; Wang, K; Wang, Q; Zhang, C; Zhao, X; Zhou, X | 1 |
| He, Q; Liu, SP | 1 |
| Liu, JH; Ma, YT; Sun, ZP | 1 |
| Ban, TT; Chang, XL; Jiang, N; Shao, CF; Wu, QE; Yao, XM; Zhou, ZJ | 1 |
| Chen, W; Huang, JX; Meng, CS; Wang, ML; Zhang, X; Zhu, QH | 1 |
| Davies, KE; Parkinson, NJ; Talbot, K; Turner, BJ | 1 |
| He, XY; Hong, GL; Hu, GX; Li, ZW; Liang, H; Lu, ZQ; Qiu, QM; Sun, Q | 1 |
| Chen, AB; Chen, JY; Hu, Q; Liang, DM; Wang, G; Yang, CY; Yuan, Y; Zhao, QY | 1 |
| Barr, DB; Buckley, B; Montesano, MA; Richfield, EK; Thiruchelvam, M; Winnik, B | 1 |
| Chang, X; Huang, M; Shao, C; Wu, Q; Zhou, Z | 1 |
| Dancheva, VY; Salovsky, PT; Shopova, VL; Stoyanova, AM | 1 |
| Guzman-Martinez, C; Jimenez-Del-Rio, M; Velez-Pardo, C | 1 |
| Baez-Garcia, CS; Cagido, VR; Contador, RS; Faffe, DS; Martini, SV; Morales, MM; Riva, DR; Rocco, PR; Xisto, DG; Zin, WA | 1 |
| Cicchetti, F; Drouin-Ouellet, J; Gross, RE | 1 |
| Borges, EL; Caliari, MV; Eleto-Silva, A; Pinheiro, MB; Rodrigues-Machado, MG | 1 |
| Berry, C; La Vecchia, C; Nicotera, P | 1 |
| He, F; He, XY; Hong, GL; Li, JR; Liang, H; Lu, ZQ; Qiu, QM | 1 |
| Chang, XL; Huang, M; Wu, Q; Zhang, P; Zhou, ZJ | 1 |
| Fitał, M; Kolasiewicz, W; Kuter, K; Nowak, P; Ossowska, K; Songin, M; Strosznajder, JB | 1 |
| Irizarry, MC; Kachroo, A; Schwarzschild, MA | 1 |
| Cuervo, AM; Di Monte, DA; Mak, SK; Manning-Bog, AB; McCormack, AL | 1 |
| Cannon, JR; Greenamyre, JT | 1 |
| Choi, HJ; Choi, JK; Kim, AY; Kim, W; Koh, EK; Koh, YH; Park, N; Park, Y; Seo, J | 1 |
| Alam, HB; Jo, YH; Kim, K; Kwon, WY; Na, SH; Rhee, JE; Suh, GJ | 1 |
| Bethune, C; Bobyn, J; Clarke, M; Hayley, S; Litteljohn, D; Mangano, EN; Peters, S; So, R | 1 |
| An, Y; Atkinson, C; Du, L; Guo, Y; Jiang, S; Qiao, F; Song, H; Sun, S; Tomlinson, S; Wang, H; Wu, X; Yu, H; Zhao, G; Zhou, Y | 1 |
| Bagatini, PB; Bernardino, GC; Coelho, GP; de Oliveira, RM; Paim, MF; Rodrigues, MF; Saur, L; Schirmer, H; Silva, DV; Souto, AA; Vianna, MR; Xavier, LL | 1 |
| Hu, GX; Li, JW; Lu, ZQ; Shen, XW; Sun, W; Tong, SH; Xiao, M; Yu, XC | 1 |
| Bajo-Grañeras, R; Ganfornina, MD; Martín-Tejedor, E; Sanchez, D | 1 |
| Cai, X; Chen, R; He, D; Xu, H | 1 |
| Sun, HC; Yang, LT; Zhi, QM | 1 |
| Gao, YF; Hu, CL; Liao, XX; Shi, J | 1 |
| Graham, LM; Miyazaki, K; Rosenbaum, MA | 1 |
| Hirano, Y; Horiuchi, J; Kuriyama, Y; Miyashita, T; Saitoe, M | 1 |
| Bové, J; Perier, C | 1 |
| Kim, H; Kim, J; Kim, K; Kim, SH; Yim, J | 1 |
| Tieu, K | 1 |
| Armentero, MT; Blandini, F | 1 |
| Bressac, C; Chevrier, C; Lécureuil, C; Nguyen, TM; Rougière, N | 1 |
| Bobyn, J; Clarke, M; Gandhi, A; Hayley, S; Mangano, EN; Moloney, K; Nelson, E | 1 |
| Fridovich-Keil, JL; Hang, D; Hopson, ML; Jones, DP; Jumbo-Lucioni, PP; Liang, Y | 1 |
| Bi, YQ; Jian, XD; Jiang, J; Liu, F; Liu, HM; Niu, YY; Shang, B; Tian, D; Zhang, W; Zhang, ZC; Zhou, Q | 1 |
| Jian, XD; Ning, Q; Wang, YC; Zhang, ZC; Zhao, B | 1 |
| Abbasi, H; Aran, S; Ghaffari, A; Keshavarz, A; Seifirad, S; Taslimi, S | 1 |
| Desplats, P; Fujita, M; Hashimoto, M; Kosberg, K; Mante, M; Masliah, E; Patel, P; Patrick, C; Rockenstein, E | 1 |
| Bonilla-Ramirez, L; Jimenez-Del-Rio, M; Velez-Pardo, C | 1 |
| Tang, X; Wang, R; Wu, X; Xie, H; Xiong, Y; Xu, R | 1 |
| Colosio, C; Moretto, A | 1 |
| Chi, B; Guo, Y; Huang, B; Liu, H; Song, B; Wu, B; Yang, H | 1 |
| Chen, M; Luo, C; Penalva, R; Xu, H | 1 |
| Costa, AC; Loh, SH; Martins, LM | 1 |
| Grasman, KA; Kimmel, EC; Whitehead, GS | 1 |
| Andressoo, JO; de Waard, H; de Wit, J; Gorgels, TG; Hoeijmakers, JH; van den Aardweg, G; van der Horst, GT; van Steeg, H; Vermeij, M | 1 |
| Di Monte, DA; McCormack, AL | 1 |
| Christians, E; Dessy, C; Foidart, JM; Gustin, P; Munaut, C; Wirth, D | 1 |
| Cheema, SS; Lopes, EC; Turner, BJ | 1 |
| Uversky, VN | 1 |
| Akahori, F; Matsuda, H; Orito, K; Shirai, M; Suzuki, Y | 1 |
| Cheng, CM; Li, X; Li, Z; Sun, JL; Wu, YL; Yin, J | 1 |
| Alamuri, P; Humayun, MZ; Maier, RJ; Taylor, DE; Wang, G | 1 |
| Chen, CM; Chou, HC; Hsu, HH; Wang, LF | 1 |
| Benítez-Díaz, P; Dávila-Ovalles, R; Miranda-Contreras, L; Palacios-Prü, E; Peña-Contreras, Z | 1 |
| Finley, B; Li, AA; McIntosh, LJ; Mink, PJ; Teta, MJ | 1 |
| Alfonso, A; Burnam, L; Hoener, M; Liu, L; Perier, C; Przedborski, S; Rodrigues, CM; Saha, S; Sluder, A; Steer, C; Ved, R; Westlund, B; Wolozin, B | 1 |
| Cicchetti, F; Ficke, BW; Gross, RE; Jimenez, L; Lapointe, N; Roberge-Tremblay, A; Saint-Pierre, M | 1 |
| Chen, SD; Du, YL; Liu, ZG; Lu, GQ | 1 |
| Gupta, YK; Kumar, A; Patel, S; Singh, MP; Singh, V | 1 |
| Kordower, JH; O'Malley, J; Soderstrom, K; Steece-Collier, K | 1 |
| Biedka, I; Bortel, A; Dabrowska, J; Kuter, K; Nowak, P; Ossowska, K; Rommelspacher, H; Schulze, G; Smiałowska, M; Wardas, J; Wierońska, J; Zieba, B | 1 |
| An, JJ; Cho, SW; Choi, HS; Choi, SY; Eum, WS; Kang, JH; Kang, TC; Kim, DW; Kim, SY; Kwon, HJ; Kwon, OS; Lee, SH; Park, J; Won, MH; Yoo, KY | 1 |
| Dias-Santagata, D; Duttaroy, A; Feany, MB; Fulga, TA | 1 |
| Hidaka, K; Ishikawa, T; Katsuyama, H; Miura, Y; Nishimura, Y; Okuyama, T; Otsuki, T; Tomita, M | 1 |
| Di Monte, DA; Khwaja, M; McCormack, A; McIntosh, JM; Quik, M | 1 |
| Bowling, K; Chaudhuri, A; Funderburk, C; Inamdar, A; Lawal, H; O'Donnell, JM; Wang, Z | 1 |
| Chu, ZH; Jian, XD; Kan, BT; Sui, H; Zhang, HT; Zhang, L; Zhang, ZW | 1 |
| Hagiwara, S; Iwasaka, H; Matsumoto, S; Noguchi, T | 1 |
| Guo, G; Jian, X; Ruan, Y; Zhang, Y | 1 |
| Chesselet, MF; Fernagut, PO; Fleming, SM; Hutson, CB; Masliah, E; Salcedo, J; Tetreaut, NA | 1 |
| Cavada, C; Cuadrado, A; de Sagarra, MR; Rojo, AI | 1 |
| Miller, GW | 1 |
| Buckley, B; Mirochnitchenko, O; Prasad, K; Richfield, EK; Thiruchelvam, MJ; Winnik, B | 1 |
| Chen, H; Gao, HB; Hu, L; Huo, SH; Liu, LD; Shi, HW; Su, JL; Tian, YP; Tong, F; Wang, X | 1 |
| Dai, MS; Lin, LF; Zheng, MH | 1 |
| Liu, JH; Lv, CH; Ma, YT; Shi, HW; Sun, ZP; Tian, YP | 1 |
| Higaki, K; Kajimaki, K; Matsuda, J; Nanba, E; Ninomiya, H; Ohno, K; Otsuka, S; Suzuki, Y; Takamura, A | 1 |
| Akahori, F; Kasahara, Y; Sakaguchi, K; Satomi, Y | 1 |
| Patel, S; Singh, K; Singh, MP; Singh, S | 1 |
| Last, JA; Reiser, KM | 1 |
| Bus, JS; Gibson, JE | 1 |
| Ishihara, Y; Kitamura, S; Kurosaki, M; Suzuki, K; Takaku, F; Yamaguchi, K | 1 |
| Haskovcová, I; Velenská, Z | 2 |
| Homma, Y | 1 |
| Carré, P; Léophonte, P | 1 |
| Shek, PN; Suntres, ZE | 1 |
| Luo, XX; Ogata, H; Xu, X | 1 |
| Itakura, Y; Kobayashi, M; Nagao, M; Oono, T; Takatori, T; Yagi, K; Yamada, Y; Zhang, WD | 1 |
| Bagetta, G; Corasaniti, MT; Nisticò, G; Rotiroti, D; Strongoli, MC | 1 |
| Saldiva, PH; Silva, MF; Zin, WA | 1 |
| Loft, S; Sørensen, M | 1 |
| Chen, RC; Chen, TH; Liou, HH; Tsai, MC; Tsai, YF | 1 |
| Allen, MJ; Mason, RJ; Nielsen, LD; Pan, T; Selman, M; Shannon, JM; Shannon, KM | 1 |
| Fukushima, T | 1 |
| Alagözlü, H; Candan, F | 1 |
| Andrews, SC; Bereswill, S; Bissé, E; Greiner, S; Guhl, J; Haas, R; Kavermann, H; Kelly, DJ; Kist, M; Kusters, JG; Odenbreit, S; Stähler, F; van Vliet, AH; Velayudhan, J; Waidner, B | 1 |
| Griffin, M; Smith, LL; Wynne, J | 1 |
| Butler, C | 1 |
| Butler, JE; Ratajczak, HV; Richards, D; Richerson, HB; Seidenfeld, JJ; Swanson, P | 1 |
| Gardiner, TH; Heaton, J; McAnalley, BH; Reynolds, RC | 1 |
| Cegla, UH; Kroidl, RF; Kronberger, H; Weber, H | 1 |
| Gordon, RE; Heller, RF | 1 |
| Gladyshev, IuV; Kolesnikov, SI; Semeniuk, AV; Sviridov, AV | 1 |
| Montaño, M; Montfort, I; Pérez-Tamayo, R; Selman, M | 1 |
| Andrzheiuk, NI; Novoselova, VP | 1 |
| Barrios, R; Montaño, M; Pérez-Tamayo, R; Ramos, C; Selman, M | 1 |
| Boda, D; Németh, I | 1 |
| Ferrans, VJ; Fukuda, Y | 1 |
| Delaval, PM; Gillespie, DJ | 1 |
| Cadot, R; Cuilleron, CY; Descotes, J; Evreux, JC; Grenot, C | 1 |
| Clements, JA; Fisher, HK; Wright, RR | 1 |
| Kimbrough, RD | 1 |
| Enhörning, G; Ivemark, B; Malmqvist, E; Modée, J; Robertson, B | 2 |
22 review(s) available for paraquat and Disease Models, Animal
| Article | Year |
|---|---|
Chemical and Genetic Zebrafish Models to Define Mechanisms of and Treatments for Dopaminergic Neurodegeneration.
Topics: Animals; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Gene Knockdown Techniques; Neurotoxicity Syndromes; Oxidopamine; Paraquat; Parkinson Disease; Parkinsonian Disorders; Protein Serine-Threonine Kinases; Rotenone; Zebrafish; Zebrafish Proteins | 2020 |
Neurotoxin-Induced Rodent Models of Parkinson's Disease: Benefits and Drawbacks.
Topics: Animals; Disease Models, Animal; Dopaminergic Neurons; Humans; Neurotoxins; Oxidopamine; Paraquat; Parkinsonian Disorders; Rodentia; Substantia Nigra | 2021 |
Mesenchymal stem cell therapy for paraquat poisoning: A systematic review and meta-analysis of preclinical studies.
Topics: Acute Lung Injury; Animals; Disease Models, Animal; Evaluation Studies as Topic; Humans; Mesenchymal Stem Cell Transplantation; Paraquat; Pulmonary Edema | 2018 |
Revisiting the Paraquat-Induced Sporadic Parkinson's Disease-Like Model.
Topics: Animals; Disease Models, Animal; Dopamine; Neurotoxicity Syndromes; Paraquat; Parkinson Disease; Substantia Nigra | 2019 |
[The efficacy of traditional Chinese medicin in animal model of lung injury induced by paraquat: a meta-analysis].
Topics: Acute Lung Injury; Animals; Disease Models, Animal; Drugs, Chinese Herbal; Male; Paraquat; Rats; Rats, Sprague-Dawley; Rats, Wistar | 2014 |
Parkinson's disease and enhanced inflammatory response.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Humans; Inflammation; Lipopolysaccharides; Neurons; Oxidative Stress; Oxidopamine; Oxygen; Paraquat; Parkinson Disease; Ubiquitin-Protein Ligases | 2015 |
Multifactorial theory applied to the neurotoxicity of paraquat and paraquat-induced mechanisms of developing Parkinson's disease.
Topics: Animals; Blood-Brain Barrier; Brain; Disease Models, Animal; Dopaminergic Neurons; Electron Transport Complex I; Energy Metabolism; Environmental Pollutants; Herbicides; Humans; Models, Neurological; NADPH Oxidases; Neurotoxins; Nitric Oxide Synthase Type I; Oxidative Stress; Paraquat; Parkinson Disease, Secondary; Risk Factors | 2016 |
Environmental toxins and Parkinson's disease: what have we learned from pesticide-induced animal models?
Topics: Animals; Disease Models, Animal; Environmental Exposure; Humans; Maneb; Paraquat; Parkinson Disease, Secondary; Pesticides; Rotenone | 2009 |
Paraquat and Parkinson's disease.
Topics: Animals; Apoptosis; Disease Models, Animal; Herbicides; Humans; Mice; Nerve Degeneration; Paraquat; Parkinson Disease; Risk Factors | 2010 |
Neurotoxic in vivo models of Parkinson's disease recent advances.
Topics: Animals; Disease Models, Animal; Dopamine; Humans; MPTP Poisoning; Neurotoxicity Syndromes; Neurotoxins; Oxidopamine; Paraquat; Parkinson Disease; Parkinson Disease, Secondary; Rotenone; Sympatholytics; Uncoupling Agents | 2010 |
Neurotoxin-based models of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Behavior, Animal; Cell Death; Disease Models, Animal; Neurotoxins; Oxidopamine; Paraquat; Parkinson Disease, Secondary; Rotenone | 2012 |
A guide to neurotoxic animal models of Parkinson's disease.
Topics: Animals; Corpus Striatum; Disease Models, Animal; Haplorhini; Lewy Bodies; Mice; MPTP Poisoning; Neurotoxins; Oxidopamine; Paraquat; Parkinson Disease; Parkinson Disease, Secondary; Rats; Rotenone; Substantia Nigra | 2011 |
Animal models of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; alpha-Synuclein; Animals; Animals, Genetically Modified; Disease Models, Animal; Dopamine Agents; Herbicides; Humans; Neurotoxins; Oxidopamine; Paraquat; Parkinson Disease; Parkinson Disease, Secondary; Sympatholytics | 2012 |
[Parasitic wasps, a model for studying male subfertility].
Topics: Animals; Body Weight; Coleoptera; Disease Models, Animal; Female; Haploidy; Host-Parasite Interactions; Hot Temperature; Infertility, Male; Larva; Male; Nymph; Paraquat; Parthenogenesis; Pest Control, Biological; Sex Ratio; Sperm Count; Spermatogenesis; Wasps | 2012 |
The role of pesticide exposure in the genesis of Parkinson's disease: epidemiological studies and experimental data.
Topics: Animals; Animals, Genetically Modified; Disease Models, Animal; Environmental Exposure; Herbicides; Humans; Paraquat; Parkinson Disease, Secondary; Parkinsonian Disorders | 2013 |
Neurotoxicant-induced animal models of Parkinson's disease: understanding the role of rotenone, maneb and paraquat in neurodegeneration.
Topics: Animals; Disease Models, Animal; Fungicides, Industrial; Herbicides; Maneb; Nerve Degeneration; Neurotoxins; Paraquat; Parkinson Disease; Rotenone; Uncoupling Agents | 2004 |
Evaluation of epidemiologic and animal data associating pesticides with Parkinson's disease.
Topics: Animals; Case-Control Studies; Dieldrin; Disease Models, Animal; Fungicides, Industrial; Heptachlor; Humans; Maneb; Occupational Diseases; Occupational Exposure; Paraquat; Parkinson Disease; Permethrin; Pesticides; Pyridazines; Risk Factors | 2005 |
Neural repair strategies for Parkinson's disease: insights from primate models.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Cell Transplantation; Deep Brain Stimulation; Disease Models, Animal; Fungicides, Industrial; Glial Cell Line-Derived Neurotrophic Factor; Herbicides; Humans; Maneb; Nerve Degeneration; Oxidopamine; Paraquat; Parkinson Disease; Pesticides; Primates; Rotenone | 2006 |
Paraquat: model for oxidant-initiated toxicity.
Topics: Animals; Disease Models, Animal; Humans; Lipid Peroxides; Lung Diseases; Oxidants, Photochemical; Oxidation-Reduction; Oxygen; Paraquat; Superoxides | 1984 |
[Cytokines and pulmonary fibroses].
Topics: Animals; Asbestos; Bleomycin; Cytokines; Disease Models, Animal; Fibroblasts; Fibronectins; Humans; Lymphocytes; Macrophages; Mice; Neutrophils; Paraquat; Pulmonary Fibrosis; Rats; Silicon Dioxide | 1993 |
Paraquat: a useful tool for the in vivo study of mechanisms of neuronal cell death.
Topics: Animals; Behavior, Animal; Blood-Brain Barrier; Brain; Cell Death; Disease Models, Animal; Herbicides; Injections, Intraventricular; Neurons; Paraquat; Rats | 1998 |
[Elucidation of paraquat poisoning mechanism and development of the neuronal death model].
Topics: Animals; Chaperonin 60; Disease Models, Animal; Electron Transport Complex I; Herbicides; Humans; Lipid Peroxidation; Mitochondria; NADH, NADPH Oxidoreductases; Niacinamide; Paraquat; Parkinson Disease; Superoxides | 2002 |
226 other study(ies) available for paraquat and Disease Models, Animal
| Article | Year |
|---|---|
Differences in epithelial-mesenchymal-transition in paraquat-induced pulmonary fibrosis in BALB/C and BALB/C (nu/nu) nude mice.
Topics: Adoptive Transfer; Animals; Cells, Cultured; Cytokines; Disease Models, Animal; Epithelial-Mesenchymal Transition; Immunocompromised Host; Inflammation Mediators; Lung; Male; Mice, Inbred BALB C; Mice, Nude; Neutrophils; Paraquat; Pulmonary Fibrosis; T-Lymphocytes | 2021 |
Naringenin alleviates paraquat-induced dopaminergic neuronal loss in SH-SY5Y cells and a rat model of Parkinson's disease.
Topics: Adenosine Triphosphate; Animals; Cell Survival; Cells, Cultured; Disease Models, Animal; Dopaminergic Neurons; Flavanones; Herbicides; Humans; Male; Membrane Potential, Mitochondrial; Neuroprotective Agents; Oxidative Stress; Paraquat; Parkinson Disease; Rats, Wistar; Substantia Nigra | 2021 |
The influence of preconditioning with low dose of LPS on paraquat-induced neurotoxicity, microglia activation and expression of α-synuclein and synphilin-1 in the dopaminergic system.
Topics: alpha-Synuclein; Animals; Carrier Proteins; Disease Models, Animal; Dopaminergic Neurons; Dose-Response Relationship, Drug; Environmental Exposure; Herbicides; Inflammation; Lipopolysaccharides; Microglia; Nerve Tissue Proteins; Neurotoxicity Syndromes; Oxidative Stress; Paraquat; Parkinson Disease; Protective Agents; Rats; Substantia Nigra | 2022 |
Chronic Exposure to Paraquat Induces Alpha-Synuclein Pathogenic Modifications in
Topics: alpha-Synuclein; Animals; Brain; Disease Models, Animal; Dopaminergic Neurons; Drosophila; Herbicides; Male; Neurotoxins; Paraquat; Parkinson Disease | 2021 |
Taurine protects dopaminergic neurons in paraquat-induced Parkinson's disease mouse model through PI3K/Akt signaling pathways.
Topics: Animals; Disease Models, Animal; Dopaminergic Neurons; Mice; Mice, Inbred C57BL; Paraquat; Parkinson Disease; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Taurine | 2022 |
5‑Aminosalicylic acid attenuates paraquat‑induced lung fibroblast activation and pulmonary fibrosis of rats.
Topics: Acute Lung Injury; Animals; Disease Models, Animal; Fibroblasts; Humans; Lung; Male; Mesalamine; Paraquat; Pulmonary Fibrosis; Rats; Signal Transduction; Transforming Growth Factor beta1 | 2022 |
Cryptotanshinone protects against oxidative stress in the paraquat-induced Parkinson's disease model.
Topics: Animals; Disease Models, Animal; Dopaminergic Neurons; Mice; Neuroprotective Agents; Oxidative Stress; Paraquat; Parkinson Disease | 2023 |
Gut dysfunction may be the source of pathological aggregation of alpha-synuclein in the central nervous system through Paraquat exposure in mice.
Topics: alpha-Synuclein; Animals; Central Nervous System; Disease Models, Animal; Fatty Acids, Volatile; Intestinal Diseases; Mice; Mice, Inbred C57BL; Paraquat | 2022 |
Integrin Mac1 mediates paraquat and maneb-induced learning and memory impairments in mice through NADPH oxidase-NLRP3 inflammasome axis-dependent microglial activation.
Topics: alpha-Synuclein; Animals; Disease Models, Animal; Dopaminergic Neurons; Inflammasomes; Integrins; Macrophage-1 Antigen; Macrophages; Maneb; Memory Disorders; Mice; Microglia; NADPH Oxidases; NLR Family, Pyrin Domain-Containing 3 Protein; Paraquat; Parkinson Disease | 2023 |
CtBP Neuroprotective Role in Toxin-Based Parkinson's Disease Models: From Expression Pattern to Dopaminergic Survival.
Topics: Animals; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Oxidopamine; Paraquat; Parkinson Disease; Rats; Substantia Nigra; Transcription Factors | 2023 |
Astaxanthin ameliorates dopaminergic neuron damage in paraquat-induced SH-SY5Y cells and mouse models of Parkinson's disease.
Topics: Animals; Disease Models, Animal; Dopaminergic Neurons; Humans; Mice; Mice, Inbred C57BL; Neuroblastoma; Paraquat; Parkinson Disease | 2023 |
Cardioprotective Effects of Atorvastatin Are Mediated Through PPARγ in Paraquat-Exposed Rats.
Topics: Animals; Antioxidants; Atorvastatin; Cardiotoxicity; Creatine Kinase, MB Form; Cyclooxygenase 2; Disease Models, Animal; Heart Diseases; Lipid Peroxidation; Male; Myocytes, Cardiac; Nitric Oxide; Oxidative Stress; Paraquat; Peroxidase; PPAR gamma; Rats, Wistar; Signal Transduction; Sulfhydryl Compounds | 2019 |
The Ocular Protective Effects of Nano/Submicron Particles Prepared from
Topics: Animals; Antioxidants; Apoptosis; Aqueous Humor; Disease Models, Animal; Electroretinography; Fruit; Glutathione Reductase; Herbicides; Immunohistochemistry; Intravitreal Injections; Lycium; Male; Models, Animal; Nanoparticles; Nanotechnology; Oxidative Stress; Paraquat; Rats; Rats, Wistar; Reactive Oxygen Species; Retina; RNA, Messenger; Superoxide Dismutase | 2020 |
Characterization of a Parkinson's disease rat model using an upgraded paraquat exposure paradigm.
Topics: Animals; Corpus Striatum; Disease Models, Animal; Dopaminergic Neurons; Paraquat; Parkinson Disease; Pars Compacta; Rats; Substantia Nigra | 2020 |
Postnatal zinc or paraquat administration increases paraquat or zinc-induced loss of dopaminergic neurons: insight into augmented neurodegeneration.
Topics: Aldehydes; Animals; Animals, Newborn; Cell Survival; Cytokines; Disease Models, Animal; Dopaminergic Neurons; Glutathione; Lipid Peroxidation; Male; Neurodegenerative Diseases; Oxidative Stress; Paraquat; Rats; Superoxide Dismutase; Zinc | 2020 |
Poloxamer 188-mediated anti-inflammatory effect rescues cognitive deficits in paraquat and maneb-induced mouse model of Parkinson's disease.
Topics: Animals; Anti-Inflammatory Agents; Behavior, Animal; Cell Proliferation; Cognition; Cognitive Dysfunction; Disease Models, Animal; Dopaminergic Neurons; Hippocampus; Inflammation Mediators; Male; Maneb; Maze Learning; Mice, Inbred C57BL; Microglia; Nerve Degeneration; Paraquat; Parkinsonian Disorders; Pars Compacta; Phagocytosis; Poloxamer; Recognition, Psychology; Synapses | 2020 |
Integrin CD11b mediates locus coeruleus noradrenergic neurodegeneration in a mouse Parkinson's disease model.
Topics: Adrenergic Neurons; Animals; CD11b Antigen; Disease Models, Animal; Inflammasomes; Locus Coeruleus; Male; Maneb; Mice; Mice, Inbred C57BL; Mice, Knockout; Microglia; Nerve Degeneration; NLR Family, Pyrin Domain-Containing 3 Protein; Paraquat; Parkinsonian Disorders; Pesticides | 2020 |
Protective effects of Lactobacillus fermentum U-21 against paraquat-induced oxidative stress in Caenorhabditis elegans and mouse models.
Topics: Animals; Antioxidants; Caenorhabditis elegans; Disease Models, Animal; Dopaminergic Neurons; Escherichia coli; Lactobacillus; Limosilactobacillus fermentum; Longevity; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Paraquat; Parkinson Disease; Survival Rate | 2020 |
Investigation of anti-Parkinson activity of dicyclomine.
Topics: Animals; Dicyclomine; Disease Models, Animal; Dopamine; Haloperidol; Mice; Paraquat; Parkinson Disease, Secondary; Parkinsonian Disorders; Substantia Nigra | 2022 |
Reduced Dpp expression accelerates inflammation-mediated neurodegeneration through activated glial cells during altered innate immune response in Drosophila.
Topics: Animals; Disease Models, Animal; Drosophila; Drosophila melanogaster; Drosophila Proteins; Immunity, Innate; Inflammation; Neurodegenerative Diseases; Neuroglia; Paraquat | 2020 |
Arenaria kansuensis attenuates pulmonary fibrosis in mice via the activation of Nrf2 pathway and the inhibition of NF-kB/TGF-beta1/Smad2/3 pathway.
Topics: Acute Lung Injury; Animals; Arenaria Plant; COVID-19; COVID-19 Drug Treatment; Cytokines; Disease Models, Animal; Drugs, Chinese Herbal; Ethanol; Female; Male; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Paraquat; Phytotherapy; Pulmonary Edema; Pulmonary Fibrosis; SARS-CoV-2; Signal Transduction; Smad2 Protein; Smad3 Protein; Survival Rate; Transforming Growth Factor beta1 | 2021 |
Thal protects against paraquat-induced lung injury through a microRNA-141/HDAC6/IκBα-NF-κB axis in rat and cell models.
Topics: Animals; Apoptosis; Cell Line; Disease Models, Animal; Female; Histone Deacetylase 6; Inflammation Mediators; Lung; Lung Injury; MicroRNAs; NF-kappa B; NF-KappaB Inhibitor alpha; Oxidative Stress; Paraquat; Protective Agents; Pulmonary Edema; Pulmonary Fibrosis; Rats, Wistar; Signal Transduction; Thalidomide | 2021 |
Inflammatory lncRNA AK039862 regulates paraquat-inhibited proliferation and migration of microglial and neuronal cells through the Pafah1b1/Foxa1 pathway in co-culture environments.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Cell Proliferation; Coculture Techniques; Disease Models, Animal; Dopaminergic Neurons; Hepatocyte Nuclear Factor 3-alpha; Herbicides; In Situ Hybridization, Fluorescence; Male; Mice; Microglia; Microtubule-Associated Proteins; Neurotoxicity Syndromes; Paraquat; RNA, Long Noncoding | 2021 |
A novel idea for establishing Parkinson's disease mouse model by intranasal administration of paraquat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Administration, Intranasal; Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Male; Mice; Mice, Inbred C57BL; Paraquat; Parkinsonian Disorders; Poloxamer | 2021 |
Characterizing the protracted neurobiological and neuroanatomical effects of paraquat in a murine model of Parkinson's disease.
Topics: Age Factors; Animals; Antigens, Surface; Brain; Caspase 1; Corticosterone; Disease Models, Animal; Dopaminergic Neurons; Inflammation; Magnetic Resonance Imaging; Male; Mice, Inbred C57BL; Milk Proteins; NF-kappa B; Paraquat; Parkinson Disease; Pesticides; Protozoan Proteins; Wiskott-Aldrich Syndrome Protein Family | 2021 |
Modeling paraquat-induced lung fibrosis in
Topics: Acute Lung Injury; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Collagen; Disease Models, Animal; DNA-Binding Proteins; Gene Expression Regulation; Gene Knockdown Techniques; Herbicides; Intracellular Signaling Peptides and Proteins; KRIT1 Protein; NF-E2-Related Factor 2; Oxidative Stress; Paraquat; Pulmonary Edema; Pulmonary Fibrosis; Transcription Factors | 2021 |
GardeninA confers neuroprotection against environmental toxin in a Drosophila model of Parkinson's disease.
Topics: Animals; Disease Models, Animal; Dopaminergic Neurons; Drosophila; Environmental Pollutants; Female; Flavones; Herbicides; Male; Neuroprotection; Neuroprotective Agents; Oxidative Stress; Paraquat; Parkinson Disease | 2021 |
Effect of Fluorofenidone Against Paraquat-Induced Pulmonary Fibrosis Based on Metabolomics and Network Pharmacology.
Topics: Animals; Autophagy; Cadherins; Disease Models, Animal; Gene Regulatory Networks; Humans; Lactosylceramides; Male; Metabolomics; Paraquat; Pulmonary Fibrosis; Pyridones; Rats; Rats, Sprague-Dawley; Signal Transduction | 2021 |
Carvacrol and PPARγ agonist, pioglitazone, affects inhaled paraquat-induced lung injury in rats.
Topics: Animals; Case-Control Studies; Cymenes; Dexamethasone; Disease Models, Animal; Drug Synergism; Gene Expression Regulation; Interleukin-6; Lung Injury; Male; Oxidative Stress; Paraquat; Pioglitazone; Rats; Rats, Wistar; Transforming Growth Factor beta; Treatment Outcome | 2021 |
Neuroprotective effects of pomegranate (Punica granatum L.) juice and seed extract in paraquat-induced mouse model of Parkinson's disease.
Topics: Animals; Apoptosis; Disease Models, Animal; Inflammation; Male; Mice; Neuroprotective Agents; Oxidative Stress; Paraquat; Parkinson Disease; Plant Extracts; Pomegranate; Seeds | 2021 |
Inhibition of NLRP3 inflammasome by glibenclamide attenuated dopaminergic neurodegeneration and motor deficits in paraquat and maneb-induced mouse Parkinson's disease model.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Antiparkinson Agents; Disease Models, Animal; Dopaminergic Neurons; Glyburide; Inflammasomes; Lipid Peroxidation; Male; Maneb; Mice, Inbred C57BL; Microglia; Motor Activity; NADPH Oxidase 2; Nerve Degeneration; Neuroprotective Agents; NF-kappa B; Nitric Oxide Synthase Type II; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Paraquat; Parkinsonian Disorders | 2021 |
Systemic inflammation and oxidative stress induced by inhaled paraquat in rat improved by carvacrol, possible role of PPARγ receptors.
Topics: Administration, Inhalation; Animals; Cymenes; Disease Models, Animal; Herbicides; Inflammation; Lung; Male; Oxidative Stress; Paraquat; PPAR gamma; Rats; Rats, Wistar | 2021 |
Ferritinophagy-Mediated Ferroptosis Involved in Paraquat-Induced Neurotoxicity of Dopaminergic Neurons: Implication for Neurotoxicity in PD.
Topics: Amino Acid Transport System y+; Animals; Autophagy; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Dopaminergic Neurons; Down-Regulation; Ferritins; Ferroptosis; Humans; Iron; Male; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Nuclear Receptor Coactivators; Paraquat; Parkinson Disease; Reactive Oxygen Species | 2021 |
HMGB1-TLR4-IL23-IL17A axis promotes paraquat-induced acute lung injury by mediating neutrophil infiltration in mice.
Topics: Acute Lung Injury; Animals; Biomarkers; Cytokines; Disease Models, Animal; HMGB1 Protein; Immunohistochemistry; Inflammation Mediators; Interleukin-17; Interleukin-23; Mice; Mice, Knockout; Neutrophil Infiltration; Neutrophils; Paraquat; Receptors, Antigen, T-Cell, gamma-delta; Signal Transduction; T-Lymphocyte Subsets; Toll-Like Receptor 4 | 2017 |
Liver X Receptor Agonist TO901317 Attenuates Paraquat-Induced Acute Lung Injury through Inhibition of NF-
Topics: Acute Lung Injury; Animals; Antioxidants; Apoptosis; Disease Models, Animal; Humans; Hydrocarbons, Fluorinated; Inflammation; Interleukin-1beta; Lipid Peroxidation; Liver X Receptors; MAP Kinase Signaling System; Mice; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Paraquat; Reactive Oxygen Species; Sulfonamides; Tumor Necrosis Factor-alpha | 2017 |
Preference of Aerosolized Pirfenidone to Oral Intake: An Experimental Model of Pulmonary Fibrosis by Paraquat.
Topics: Administration, Inhalation; Administration, Oral; Aerosols; Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Delivery Systems; Male; Oxidative Stress; Paraquat; Pulmonary Fibrosis; Pyridones; Rats; Rats, Sprague-Dawley | 2018 |
Neuroprotective effects of coenzyme Q10 on paraquat-induced Parkinson's disease in experimental animals.
Topics: Animals; Disease Models, Animal; Levodopa; Male; Mice; Mitochondria; Neurons; Neuroprotective Agents; Oxidative Stress; Paraquat; Parkinson Disease; Protein Carbonylation; Ubiquinone | 2018 |
A Nigro-Vagal Pathway Controls Gastric Motility and Is Affected in a Rat Model of Parkinsonism.
Topics: Animals; Brain Stem; Disease Models, Animal; Gastric Emptying; Immunohistochemistry; Male; Motor Activity; Neural Pathways; Neuroanatomical Tract-Tracing Techniques; Neurotransmitter Agents; Optogenetics; Paraquat; Parkinson Disease, Secondary; Pars Compacta; Rats, Sprague-Dawley; Receptors, Dopamine D1; Stomach; Time Factors; Vagus Nerve | 2017 |
Combination Therapy with Pirfenidone plus Prednisolone Ameliorates Paraquat-Induced Pulmonary Fibrosis.
Topics: Animals; Anti-Inflammatory Agents; Cytoprotection; Disease Models, Animal; Drug Therapy, Combination; Gene Expression Regulation; Glucocorticoids; Hydroxyproline; Inflammation Mediators; Lung; Male; Matrix Metalloproteinase 2; Oxidative Stress; Paraquat; Prednisolone; Pulmonary Fibrosis; Pyridones; Rats, Sprague-Dawley; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha | 2018 |
Protective Effects of Chymostatin on Paraquat-Induced Acute Lung Injury in Mice.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Cathepsin G; Cytokines; Cytoprotection; Disease Models, Animal; Female; HMGB1 Protein; Inflammation Mediators; Lung; Mice, Inbred ICR; Oligopeptides; Paraquat; Proteoglycans; Pulmonary Edema; Time Factors; Transcription Factor RelA | 2018 |
Triptolide suppresses paraquat induced idiopathic pulmonary fibrosis by inhibiting TGFB1-dependent epithelial mesenchymal transition.
Topics: Animals; Cell Line; Cell Movement; Disease Models, Animal; Diterpenes; Drugs, Chinese Herbal; Epithelial Cells; Epithelial-Mesenchymal Transition; Epoxy Compounds; Humans; Idiopathic Pulmonary Fibrosis; Lung; Mice; Molecular Docking Simulation; Paraquat; Phenanthrenes; Protein Binding; Transforming Growth Factor beta1 | 2018 |
Necrostatin-1 Protects Against Paraquat-Induced Cardiac Contractile Dysfunction via RIP1-RIP3-MLKL-Dependent Necroptosis Pathway.
Topics: Animals; Antioxidants; Calcium Signaling; Cardiotoxicity; Cell Death; Cytoprotection; Disease Models, Animal; GTPase-Activating Proteins; Imidazoles; Indoles; Mice, Inbred C57BL; Myocardial Contraction; Myocytes, Cardiac; Oxidative Stress; Paraquat; Protein Kinases; Reactive Oxygen Species; Receptor-Interacting Protein Serine-Threonine Kinases; Ventricular Dysfunction, Left; Ventricular Function, Left | 2018 |
HFE Genotype Restricts the Response to Paraquat in a Mouse Model of Neurotoxicity.
Topics: Animals; Brain; Disease Models, Animal; Gastrointestinal Microbiome; Gene-Environment Interaction; Genetic Variation; Genotype; Hemochromatosis Protein; Herbicides; Mice; Mice, Transgenic; Neurotoxicity Syndromes; Paraquat; Parkinson Disease; Tyrosine 3-Monooxygenase | 2018 |
Imbalance of Th17/Treg in the Pathogenesis of Mice with Paraquat-induced Acute Lung Injury.
Topics: Acute Lung Injury; Animals; Apoptosis; Biomarkers; Cytokines; Disease Models, Animal; Herbicides; Immunohistochemistry; Immunophenotyping; Lymphocyte Count; Male; Mice; Paraquat; T-Lymphocytes, Regulatory; Th17 Cells | 2017 |
Astrocytic JWA deletion exacerbates dopaminergic neurodegeneration by decreasing glutamate transporters in mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amino Acid Transport System X-AG; Animals; Astrocytes; Carrier Proteins; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Excitatory Amino Acid Transporter 2; Gene Knockout Techniques; Glial Fibrillary Acidic Protein; Glutamic Acid; Heat-Shock Proteins; Male; Membrane Transport Proteins; Mice; Mice, Knockout; Mitogen-Activated Protein Kinases; MPTP Poisoning; Neurogenesis; Neurotoxins; Paraquat; Phosphatidylinositol 3-Kinases; STAT3 Transcription Factor | 2018 |
Taurine protects dopaminergic neurons in a mouse Parkinson's disease model through inhibition of microglial M1 polarization.
Topics: alpha-Synuclein; Animals; Disease Models, Animal; Dopaminergic Neurons; Gait; Gene Expression; Male; Maneb; Mice; Mice, Inbred C57BL; Microglia; NADPH Oxidase 2; NADPH Oxidases; Neuroprotective Agents; NF-kappa B; Paraquat; Parkinson Disease, Secondary; Signal Transduction; Taurine | 2018 |
Neuroprotective action of 4-Hydroxyisophthalic acid against paraquat-induced motor impairment involves amelioration of mitochondrial damage and neurodegeneration in Drosophila.
Topics: Acetylcholinesterase; Animals; Brain; Disease Models, Animal; Drosophila melanogaster; Female; Herbicides; Male; Mitochondria; Motor Activity; Movement Disorders; Neuroprotective Agents; Oxidative Stress; Paraquat; Parkinson Disease, Secondary; Phthalic Acids | 2018 |
Epigallocatechin-3-Gallate Protects and Prevents Paraquat-Induced Oxidative Stress and Neurodegeneration in Knockdown dj-1-β Drosophila melanogaster.
Topics: Animals; Animals, Genetically Modified; Antioxidants; Catechin; Disease Models, Animal; Dose-Response Relationship, Drug; Drosophila melanogaster; Drosophila Proteins; Female; Herbicides; Lipid Peroxidation; Locomotion; Male; Minocycline; Nerve Tissue Proteins; Neurodegenerative Diseases; Neuroprotective Agents; Oxidative Stress; Paraquat; Protein Deglycase DJ-1; Tyrosine 3-Monooxygenase | 2018 |
The activation of STIM1 mediates S-phase arrest and cell death in paraquat induced acute lung intoxication.
Topics: Acute Lung Injury; Animals; Calcium Signaling; Cell Cycle Proteins; Cell Death; Cell Line; Cell Proliferation; Disease Models, Animal; Epithelial Cells; Lung; Male; Mice, Inbred C57BL; Neoplasm Proteins; Oxidative Stress; Paraquat; S Phase Cell Cycle Checkpoints; Stromal Interaction Molecule 1 | 2018 |
Apple procyanidins promote mitochondrial biogenesis and proteoglycan biosynthesis in chondrocytes.
Topics: Animals; Cartilage, Articular; Cell Line; Chondrocytes; Disease Models, Animal; DNA, Mitochondrial; Gene Expression; Humans; Male; Malus; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Organelle Biogenesis; Osteoarthritis; Paraquat; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Polyphenols; Primary Cell Culture; Proanthocyanidins; Proteoglycans; Superoxide Dismutase | 2018 |
Prolonged low-dose cyclophosphamide treatment after pulse therapy attenuates lung injury in rats with paraquat intoxication.
Topics: Acute Lung Injury; Animals; Biomarkers; Cyclophosphamide; Cytoprotection; Disease Models, Animal; Drug Administration Schedule; Hydroxyproline; Immunosuppressive Agents; Injections, Intraperitoneal; Lung; Paraquat; Pulmonary Edema; Pulmonary Fibrosis; Pulse Therapy, Drug; Rats, Wistar; Time Factors | 2018 |
Tanshinone IIA attenuates paraquat‑induced acute lung injury by modulating angiotensin‑converting enzyme 2/angiotensin‑(1‑7) in rats.
Topics: Abietanes; Acute Lung Injury; Angiotensin I; Angiotensin-Converting Enzyme 2; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Biopsy; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Gene Expression; Immunohistochemistry; L-Lactate Dehydrogenase; Male; Neutrophil Infiltration; Paraquat; Peptide Fragments; Peptidyl-Dipeptidase A; Rats | 2018 |
The KCa3.1 blocker TRAM-34 inhibits proliferation of fibroblasts in paraquat-induced pulmonary fibrosis.
Topics: Actins; Animals; Cell Proliferation; Cells, Cultured; Collagen Type I; Disease Models, Animal; Fibroblasts; Intermediate-Conductance Calcium-Activated Potassium Channels; Lung; Male; Paraquat; Potassium Channel Blockers; Pulmonary Fibrosis; Pyrazoles; Rats, Sprague-Dawley; Signal Transduction; Time Factors; Transforming Growth Factor beta1 | 2018 |
Mutation of hop-1 and pink-1 attenuates vulnerability of neurotoxicity in C. elegans: the role of mitochondria-associated membrane proteins in Parkinsonism.
Topics: Adenosine Triphosphate; Animals; Animals, Genetically Modified; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Green Fluorescent Proteins; Membrane Potential, Mitochondrial; Membrane Proteins; Microscopy, Electron, Transmission; Mitochondria; Mitochondrial Diseases; Mitochondrial Proteins; Movement; Mutation; Paraquat; Parkinsonian Disorders; Protein Serine-Threonine Kinases; Rotenone | 2018 |
Rapamycin reduces mortality in acute-stage paraquat-induced toxicity in zebrafish.
Topics: Acute Disease; Animals; Disease Models, Animal; Paraquat; Sirolimus; Survival Rate; Zebrafish | 2019 |
[Exploration about the protection mechanism of 5-hydroxy-1-methylhydantoin on paraquat poisoning model].
Topics: Acute Kidney Injury; Animals; Disease Models, Animal; Hydantoins; Mice; Paraquat; Protective Agents | 2018 |
Tribolium castaneum as a whole-animal screening system for the detection and characterization of neuroprotective substances.
Topics: Animals; Diet; Dietary Supplements; Disease Models, Animal; Drug Evaluation, Preclinical; Neuroprotective Agents; Paraquat; Parkinson Disease; Tribolium | 2019 |
Neuroprotective effects of PACAP against paraquat-induced oxidative stress in the Drosophila central nervous system.
Topics: Animals; Central Nervous System; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Drosophila Proteins; Humans; Neuroprotective Agents; Neurotoxicity Syndromes; Oxidative Stress; Paraquat; Parkinson Disease; Pituitary Adenylate Cyclase-Activating Polypeptide; Reactive Oxygen Species; Receptors, G-Protein-Coupled | 2019 |
Selective mitochondrial superoxide generation in vivo is cardioprotective through hormesis.
Topics: Animals; Animals, Newborn; Apoptosis; Disease Models, Animal; Herbicides; Hormesis; Male; Mice; Mice, Inbred C57BL; Mitochondria, Heart; Myocardial Reperfusion Injury; Myocytes, Cardiac; Paraquat; Rats; Rats, Wistar; Superoxides | 2019 |
Role of bone marrow mesenchymal stem cells in the development of PQ‑induced pulmonary fibrosis.
Topics: Alveolar Epithelial Cells; Animals; Apoptosis; Biomarkers; Disease Models, Animal; Endothelial Cells; Epithelial-Mesenchymal Transition; Herbicides; Immunohistochemistry; Male; Mesenchymal Stem Cells; Mice; Paraquat; Pulmonary Fibrosis | 2019 |
Reduning injection ameliorates paraquat-induced acute lung injury by regulating AMPK/MAPK/NF-κB signaling.
Topics: A549 Cells; Acute Lung Injury; Administration, Oral; AMP-Activated Protein Kinases; Animals; Dexamethasone; Disease Models, Animal; Drugs, Chinese Herbal; Gene Expression Regulation; Humans; Injections, Intraperitoneal; Male; Mice; Mitogen-Activated Protein Kinases; NF-kappa B; Paraquat; Peroxidase; Phosphorylation; Signal Transduction | 2019 |
Melittin Exerts Beneficial Effects on Paraquat-Induced Lung Injuries In Mice by Modifying Oxidative Stress and Apoptosis.
Topics: Animals; Apoptosis; Biopsy; Catalase; Disease Models, Animal; Glutathione Peroxidase; Histocytochemistry; Lung Injury; Malondialdehyde; Melitten; Mice; Nitric Oxide; Oxidation-Reduction; Oxidative Stress; Paraquat; Proto-Oncogene Proteins c-bcl-2; Superoxide Dismutase | 2019 |
Altered gastric tone and motility response to brain-stem dopamine in a rat model of parkinsonism.
Topics: Animals; Brain Stem; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Gastrointestinal Motility; Male; Neural Inhibition; Neuronal Plasticity; Paraquat; Parkinsonian Disorders; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Stomach; Vagus Nerve | 2019 |
Paraquat Preferentially Induces Apoptosis of Late Stage Effector Lymphocyte and Impairs Memory Immune Response in Mice.
Topics: Adaptive Immunity; Adjuvants, Immunologic; Animals; Apoptosis; Disease Models, Animal; Female; Hemocyanins; Herbicides; Immunologic Memory; Mice; Mice, Inbred C57BL; Paraquat | 2019 |
Neuroprotective role of Withania somnifera root extract in maneb-paraquat induced mouse model of parkinsonism.
Topics: Animals; Disease Models, Animal; Maneb; Mice; Neuroprotective Agents; Paraquat; Parkinsonian Disorders; Plant Extracts; Plant Roots; Withania | 2013 |
PACAP deficiency sensitizes nigrostriatal dopaminergic neurons to paraquat-induced damage and modulates central and peripheral inflammatory activation in mice.
Topics: Analysis of Variance; Animals; Calcium-Binding Proteins; Disease Models, Animal; DNA-Binding Proteins; Dopaminergic Neurons; Herbicides; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microfilament Proteins; Microglia; Neurotoxicity Syndromes; Paraquat; Pituitary Adenylate Cyclase-Activating Polypeptide; Substantia Nigra; T-Lymphocytes; Tumor Necrosis Factor-alpha; Tyrosine 3-Monooxygenase | 2013 |
[Effect of thalidomide in a mouse model of paraquat-induced acute lung injury and the underlying mechanisms].
Topics: Acute Lung Injury; Animals; Cytokines; Disease Models, Animal; Male; Mice; Mice, Inbred ICR; NF-kappa B p50 Subunit; Paraquat; Thalidomide; Transcription Factor RelA | 2013 |
Mucuna pruriens seed extract reduces oxidative stress in nigrostriatal tissue and improves neurobehavioral activity in paraquat-induced Parkinsonian mouse model.
Topics: Animals; Behavior, Animal; Catalase; Corpus Striatum; Disease Models, Animal; Male; Malondialdehyde; Mice; Mucuna; Oxidative Stress; Paraquat; Parkinsonian Disorders; Plant Extracts; Seeds; Substantia Nigra | 2013 |
Minocycline, levodopa and MnTMPyP induced changes in the mitochondrial proteome profile of MPTP and maneb and paraquat mice models of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Disease Models, Animal; Dopamine; Homeodomain Proteins; Levodopa; Male; Maneb; Metalloporphyrins; Mice; Microglia; Minocycline; Mitochondria; Paraquat; Parkinson Disease, Secondary; Proteome; Stathmin; Superoxide Dismutase | 2013 |
[Effects of pyrrolidine dithiocarbamate on expressions of α-smooth muscle actin, integrin α5 and fibronectin in acute paraquat poisoned rats].
Topics: Actins; Animals; Disease Models, Animal; Fibronectins; Integrin alpha5; Male; Paraquat; Pulmonary Fibrosis; Pyrrolidines; Rats; Rats, Sprague-Dawley; Thiocarbamates | 2013 |
The dose of cyclophosphamide for treating paraquat-induced rat lung injury.
Topics: Acute Lung Injury; Animals; Catalase; Cyclophosphamide; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Immunosuppressive Agents; Inflammation Mediators; Lung; Lung Injury; Male; Oxidative Stress; Paraquat; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Superoxide Dismutase; Transforming Growth Factor beta1; X-Ray Microtomography | 2013 |
Silymarin- and melatonin-mediated changes in the expression of selected genes in pesticides-induced Parkinsonism.
Topics: Animals; Antioxidants; Apoptosis; Cell Cycle; Disease Models, Animal; Gene Expression Regulation; Inflammation; Ion Channels; Male; Maneb; Melatonin; Mice; Mitochondria; Oxidative Stress; Paraquat; Parkinsonian Disorders; Pesticides; Signal Transduction; Silymarin | 2013 |
Using bosentan to treat paraquat poisoning-induced acute lung injury in rats.
Topics: Acute Lung Injury; Alveolar Epithelial Cells; Animals; Bosentan; Disease Models, Animal; Endothelin-1; Hydroxyproline; Male; Paraquat; Rats; Rats, Wistar; Sulfonamides; Transforming Growth Factor beta1 | 2013 |
Effect of lung fibrosis on glycogen content in different extrapulmonary tissues.
Topics: Animals; Bleomycin; Diaphragm; Disease Models, Animal; Glycogen; Lung; Male; Mice; Mice, Inbred BALB C; Muscle, Skeletal; Myocardium; Paraquat; Pulmonary Fibrosis; Rats; Rats, Wistar | 2014 |
Parkinson's disease, lights and melanocytes: looking beyond the retina.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Disease Models, Animal; Female; Light; Male; Melanocytes; Motor Activity; Oxidopamine; Paraquat; Parkinson Disease; Rats; Rats, Sprague-Dawley; Retina; Rotenone | 2014 |
Consequences of developmental exposure to concentrated ambient ultrafine particle air pollution combined with the adult paraquat and maneb model of the Parkinson's disease phenotype in male mice.
Topics: Air Pollutants; Animals; Animals, Newborn; Cell Count; Corpus Striatum; Disease Models, Animal; Drug Combinations; Female; Fungicides, Industrial; Herbicides; Male; Maneb; Mice; Mice, Inbred C57BL; Motor Activity; Nanoparticles; Paraquat; Parkinson Disease; Particulate Matter; Silicones; Substantia Nigra; Tyrosine 3-Monooxygenase | 2014 |
Environmental neurotoxic challenge of conditional alpha-synuclein transgenic mice predicts a dopaminergic olfactory-striatal interplay in early PD.
Topics: Aged; Aged, 80 and over; alpha-Synuclein; Alzheimer Disease; Animals; Autophagy; Cell Line, Tumor; Corpus Striatum; Disease Models, Animal; Dopaminergic Neurons; Female; Gene Expression Regulation; Humans; Male; Mice; Mice, Transgenic; Mutation; Neural Pathways; Neurotoxins; Olfactory Bulb; Paraquat | 2014 |
Localized changes to glycogen synthase kinase-3 and collapsin response mediator protein-2 in the Huntington's disease affected brain.
Topics: Adenosine Triphosphate; Aged; Aged, 80 and over; Animals; beta Catenin; Cell Line; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Female; Gene Expression Regulation; Glycogen Synthase Kinase 3; Humans; Huntingtin Protein; Huntington Disease; Intercellular Signaling Peptides and Proteins; Male; Mice; Mice, Transgenic; Middle Aged; Nerve Tissue Proteins; Neurons; Paraquat; Phosphorylation; Signal Transduction | 2014 |
Allopurinol reduces levels of urate and dopamine but not dopaminergic neurons in a dual pesticide model of Parkinson's disease.
Topics: Allopurinol; Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Enzyme Inhibitors; Male; Maneb; Mice; Mice, Inbred C57BL; Motor Activity; Paraquat; Parkinson Disease; Pesticides; Uric Acid | 2014 |
Heat shock protein-70 (Hsp-70) suppresses paraquat-induced neurodegeneration by inhibiting JNK and caspase-3 activation in Drosophila model of Parkinson's disease.
Topics: Animals; Apoptosis; Caspase 3; Disease Models, Animal; Dopaminergic Neurons; Drosophila melanogaster; Drosophila Proteins; HSP70 Heat-Shock Proteins; JNK Mitogen-Activated Protein Kinases; Motor Activity; Oxidative Stress; Paraquat; Parkinsonian Disorders; Up-Regulation | 2014 |
FTY720 attenuates paraquat-induced lung injury in mice.
Topics: Actins; Acute Lung Injury; Animals; Body Weight; Bronchoalveolar Lavage Fluid; Collagen Type I; Collagen Type III; Disease Models, Animal; Fingolimod Hydrochloride; Interleukin-1beta; Interleukin-6; Lung; Lung Injury; Mice; Mice, Inbred C57BL; Paraquat; Propylene Glycols; Pulmonary Edema; Pulmonary Fibrosis; Sphingosine; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2014 |
[Total flavonoids from Astragalus complanatus attenuates lung injury following paraquat poisoning in rats through inhibiting excessive endoplasmic reticulum stress and c-Jun N-terminal kinase pathway].
Topics: Acute Disease; Animals; Astragalus Plant; Disease Models, Animal; Endoplasmic Reticulum Stress; Flavonoids; JNK Mitogen-Activated Protein Kinases; Lung Injury; Male; Paraquat; Rats; Rats, Sprague-Dawley; Signal Transduction | 2014 |
[Reproduction of acute lung injury model induced by paraquat in piglet].
Topics: Acute Lung Injury; Animals; Disease Models, Animal; Female; Paraquat; Swine | 2014 |
[The interventional effect of Xuebijing injection on expression of mitochondrial fusion protein 2 and the ultrastructure changes in lung tissues in rats with paraquat poisoning].
Topics: Animals; Disease Models, Animal; Drugs, Chinese Herbal; GTP Phosphohydrolases; Lung; Male; Membrane Proteins; Mitochondria; Mitochondrial Proteins; Paraquat; Rats; Rats, Wistar | 2014 |
[Tumor necrosis factor-α induced protein 6 attenuates acute kidney injury following paraquat poisoning in rats].
Topics: Acute Kidney Injury; Animals; Cell Adhesion Molecules; Disease Models, Animal; Male; Paraquat; Rats; Rats, Sprague-Dawley; Recombinant Proteins | 2014 |
MDR1 transporter protects against paraquat-induced toxicity in human and mouse proximal tubule cells.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; Cyclosporins; Disease Models, Animal; Gene Expression Regulation; HEK293 Cells; Herbicides; Humans; Kidney Diseases; Kidney Tubules, Proximal; Mice, Inbred C57BL; Mice, Knockout; Paraquat; Renal Elimination; RNA Interference; RNA, Messenger; Time Factors; Transfection | 2014 |
Induced pluripotent stem cells without c-Myc ameliorate retinal oxidative damage via paracrine effects and reduced oxidative stress in rats.
Topics: Animals; Apoptosis; Brain-Derived Neurotrophic Factor; Cell Line, Tumor; Chemokine CXCL12; Disease Models, Animal; Electroretinography; Humans; Induced Pluripotent Stem Cells; Mice; Mice, Inbred C57BL; Oxidative Stress; Paracrine Communication; Paraquat; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Retinal Diseases; Superoxide Dismutase | 2014 |
A dopamine receptor contributes to paraquat-induced neurotoxicity in Drosophila.
Topics: Age Factors; Animals; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Drosophila melanogaster; Drosophila Proteins; Environmental Exposure; Female; Humans; Neurotoxicity Syndromes; Paraquat; Parkinson Disease; Receptors, Dopamine; Receptors, Dopamine D1; Ryanodine Receptor Calcium Release Channel | 2015 |
Synergistic effects on dopamine cell death in a Drosophila model of chronic toxin exposure.
Topics: Animals; Cell Death; Disease Models, Animal; Dopaminergic Neurons; Drosophila melanogaster; Maneb; Motor Activity; Paraquat; Parkinson Disease, Secondary; Pesticides; Survival Analysis; Ubiquitin-Protein Ligases; Ziram | 2014 |
[Curcumin alleviated liver oxidative stress injury of rat induced by paraquat].
Topics: Animals; Catalase; Curcumin; Disease Models, Animal; Heme Oxygenase (Decyclizing); Liver; Male; Malondialdehyde; NAD(P)H Dehydrogenase (Quinone); Oxidative Stress; Paraquat; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2014 |
Curcumin's neuroprotective efficacy in Drosophila model of idiopathic Parkinson's disease is phase specific: implication of its therapeutic effectiveness.
Topics: Animals; Brain; Chromatography, High Pressure Liquid; Curcumin; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Drosophila melanogaster; Drug Resistance; Humans; Longevity; Movement; Neuroprotective Agents; Paraquat; Parkinson Disease; Time Factors; Treatment Outcome | 2014 |
The mechanism of rapamycin in the intervention of paraquat-induced acute lung injury in rats.
Topics: Acute Lung Injury; Animals; Disease Models, Animal; Female; Herbicides; Male; Paraquat; Rats; Rats, Wistar; Sirolimus | 2015 |
Effects of rapamycin against paraquat-induced pulmonary fibrosis in mice.
Topics: Actins; Animals; Body Weight; Collagen; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Herbicides; Immunohistochemistry; Immunosuppressive Agents; Lung; Male; Methylprednisolone; Mice; Mice, Inbred C57BL; Paraquat; Prognosis; Pulmonary Fibrosis; Sirolimus; Transforming Growth Factor beta1; Treatment Outcome | 2015 |
[Effect of thalidomide in a mouse model of paraquat-induced acute lung injury and the underlying mechanisms].
Topics: Acute Lung Injury; Animals; Disease Models, Animal; Lung; Male; Malondialdehyde; Mice; Mice, Inbred ICR; NF-E2-Related Factor 2; Paraquat; Signal Transduction; Thalidomide | 2014 |
Selenium reduces bradykinesia and DNA damage in a rat model of Parkinson's disease.
Topics: Animals; Comet Assay; Disease Models, Animal; DNA Damage; Hypokinesia; Male; Paraquat; Parkinson Disease; Rats; Rats, Wistar; Selenium | 2015 |
Acute Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) or Paraquat on Core Temperature in C57BL/6J Mice.
Topics: Animals; Body Temperature; Corpus Striatum; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; MPTP Poisoning; Paraquat; Parkinsonian Disorders; Purines; Substantia Nigra | 2015 |
Effects of different tidal volume ventilation on paraquat-induced acute lung injury in piglets.
Topics: Acute Lung Injury; Animals; Blood Gas Analysis; Cardiac Output; Disease Models, Animal; Hemodynamics; Herbicides; Injections, Intraperitoneal; Paraquat; Positive-Pressure Respiration; Respiratory Distress Syndrome; Swine; Tidal Volume; Time Factors | 2015 |
Salidroside alleviates paraquat-induced rat acute lung injury by repressing TGF-β1 expression.
Topics: Acute Lung Injury; Animals; Disease Models, Animal; Glucosides; Herbicides; Immunohistochemistry; Lung; Male; Paraquat; Phenols; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Transforming Growth Factor beta1 | 2014 |
Formation and Implications of Alpha-Synuclein Radical in Maneb- and Paraquat-Induced Models of Parkinson's Disease.
Topics: alpha-Synuclein; Animals; Cyclic N-Oxides; Disease Models, Animal; Dopaminergic Neurons; Injections, Intraperitoneal; Male; Maneb; Mesencephalon; Mice, Inbred C57BL; Microglia; Models, Biological; NADPH Oxidases; Nitric Oxide Synthase Type II; Paraquat; Parkinson Disease; Peroxynitrous Acid; Spin Labels; Substantia Nigra; Tyrosine 3-Monooxygenase | 2016 |
Cardiac-Specific Knockout of ETA Receptor Mitigates Paraquat-Induced Cardiac Contractile Dysfunction.
Topics: Animals; Apoptosis; Calcium Signaling; Cardiotoxicity; Disease Models, Animal; Female; Heart Diseases; HSP90 Heat-Shock Proteins; Male; Mice, Knockout; Mitochondria, Heart; Myocardial Contraction; Myocytes, Cardiac; Oxidative Phosphorylation; Paraquat; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Receptor, Endothelin A; Uncoupling Protein 2; Ventricular Function, Left | 2016 |
NLRP3 inflammasome activation by mitochondrial reactive oxygen species plays a key role in long-term cognitive impairment induced by paraquat exposure.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Carrier Proteins; Cognition Disorders; Disease Models, Animal; Electron Transport Complex I; Electron Transport Complex IV; Herbicides; Humans; Hydrogen Peroxide; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondria; Nerve Tissue Proteins; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Paraquat; Presenilin-1; Reactive Oxygen Species | 2015 |
Rapamycin reverses paraquat-induced acute lung injury in a rat model through inhibition of NFκB activation.
Topics: Acute Lung Injury; Animals; Biomarkers; Bronchoalveolar Lavage Fluid; Carbon Dioxide; Disease Models, Animal; Glutathione Peroxidase; Hydrogen-Ion Concentration; Lung; Male; Malondialdehyde; Neutrophils; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Paraquat; Phosphorylation; Rats, Sprague-Dawley; Signal Transduction; Sirolimus; Superoxide Dismutase; Time Factors | 2015 |
Involvement of epithelial-to-mesenchymal transition and associated transforming growth factor-β/Smad signaling in paraquat-induced pulmonary fibrosis.
Topics: Actins; Animals; Cadherins; Cell Line, Tumor; Disease Models, Animal; Epithelial-Mesenchymal Transition; Herbicides; Humans; Male; Paraquat; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; RNA Interference; RNA, Small Interfering; Signal Transduction; Smad2 Protein; Transforming Growth Factor beta1; Vimentin | 2015 |
Evidence of neuroprotective effects of saffron and crocin in a Drosophila model of parkinsonism.
Topics: Acetylcholinesterase; Animals; Antioxidants; Biomarkers; Carotenoids; Crocus; Disease Models, Animal; Dopamine; Drosophila melanogaster; Glutathione; Hydrogen Peroxide; Locomotion; Longevity; Mitochondria; Neuroprotective Agents; Nitric Oxide; Oxidative Stress; Paraquat; Parkinsonian Disorders; Phytotherapy; Plant Extracts; Protein Carbonylation; Reactive Oxygen Species; Rotenone; Sulfhydryl Compounds | 2016 |
Hyperbaric oxygen treatment ameliorates lung injury in paraquat intoxicated rats.
Topics: Acute Lung Injury; Animals; Disease Models, Animal; Herbicides; Hyperbaric Oxygenation; Male; Oxidative Stress; Paraquat; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction | 2015 |
Radix puerariae extracts ameliorate paraquat-induced pulmonary fibrosis by attenuating follistatin-like 1 and nuclear factor erythroid 2p45-related factor-2 signalling pathways through downregulation of miRNA-21 expression.
Topics: Animals; Antioxidants; Collagen; Disease Models, Animal; Down-Regulation; Drugs, Chinese Herbal; Follistatin-Related Proteins; Gene Knockdown Techniques; Herbicides; Mice; Mice, Inbred C57BL; MicroRNAs; NF-E2-Related Factor 2; Paraquat; Pueraria; Pulmonary Fibrosis; Reactive Oxygen Species; Signal Transduction | 2016 |
KLF2 and caveolin-1 as early indicators of acute lung injury induced by paraquat.
Topics: Acute Lung Injury; Animals; Caveolin 1; Disease Models, Animal; Herbicides; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Lung; Male; Paraquat; Rats; Rats, Wistar | 2016 |
Integrated long non-coding RNA analyses identify novel regulators of epithelial-mesenchymal transition in the mouse model of pulmonary fibrosis.
Topics: A549 Cells; Animals; Disease Models, Animal; Epithelial Cells; Epithelial-Mesenchymal Transition; Gene Expression Profiling; Gene Ontology; Homeodomain Proteins; Humans; Lung; Mice, Inbred BALB C; Paraquat; Pulmonary Fibrosis; Repressor Proteins; Reproducibility of Results; RNA, Long Noncoding; Zinc Finger E-box Binding Homeobox 2 | 2016 |
Unfractionated bone marrow cells attenuate paraquat-induced glomerular injury and acute renal failure by modulating the inflammatory response.
Topics: Acute Kidney Injury; Animals; Bone Marrow Transplantation; Cells, Cultured; Cytokines; Disease Models, Animal; Female; Gene Expression Regulation; Intracellular Signaling Peptides and Proteins; Kidney Glomerulus; Membrane Proteins; Mice; Paraquat; Th1 Cells; Th2 Cells | 2016 |
Oxidative Stress Triggers Body-Wide Skipping of Multiple Exons of the Spinal Muscular Atrophy Gene.
Topics: Alternative Splicing; Animals; Base Sequence; Biological Assay; Disease Models, Animal; Exons; Gene Expression; Humans; Introns; Mice; Mice, Transgenic; Motor Neurons; Muscular Atrophy, Spinal; Nucleic Acid Conformation; Oxidative Stress; Paraquat; Survival of Motor Neuron 1 Protein; Survival of Motor Neuron 2 Protein; Transgenes | 2016 |
Poly-ADP-ribose polymerase inhibition provides protection against lung injury in a rat paraquat toxicity model.
Topics: Animals; Antioxidants; Benzamides; Biomarkers; Disease Models, Animal; Female; Injections, Intraperitoneal; Lipid Peroxidation; Lung Injury; Neopterin; Paraquat; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats, Sprague-Dawley | 2016 |
Curcumin inhibits paraquat induced lung inflammation and fibrosis by extracellular matrix modifications in mouse model.
Topics: Acute Lung Injury; Administration, Intranasal; Animals; Anti-Inflammatory Agents; Collagen; Curcumin; Disease Models, Animal; Fibrosis; Lung; Male; Mice, Inbred Strains; Oxidative Stress; Paraquat; Pneumonia | 2016 |
Paraquat Induces Peripheral Myelin Disruption and Locomotor Defects: Crosstalk with LXR and Wnt Pathways.
Topics: Animals; Cell Line; Demyelinating Diseases; Disease Models, Animal; Gene Expression Regulation; Herbicides; Lipid Peroxidation; Liver X Receptors; Male; Mice; Myelin Proteins; Myelin Sheath; Oxidative Stress; Paraquat; Protein Aggregation, Pathological; Protein Carbonylation; Reactive Oxygen Species; Schwann Cells; Wnt Signaling Pathway | 2017 |
Effects of decreased dopamine transporter levels on nigrostriatal neurons and paraquat/maneb toxicity in mice.
Topics: Aging; Animals; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Genetic Variation; Male; Maneb; Mice, Knockout; Mice, Mutant Strains; Paraquat; Parkinson Disease; Pars Compacta; Risk | 2017 |
Tualang Honey Protects the Rat Midbrain and Lung against Repeated Paraquat Exposure.
Topics: Animals; Antioxidants; Disease Models, Animal; Herbicides; Honey; Immunohistochemistry; Lung; Male; Mesencephalon; Neuroprotective Agents; Paraquat; Rats; Rats, Sprague-Dawley | 2017 |
Supplementation of Spirulina (Arthrospira platensis) Improves Lifespan and Locomotor Activity in Paraquat-Sensitive DJ-1β
Topics: Animals; Antioxidants; Dietary Supplements; Disease Models, Animal; Drosophila melanogaster; Herbicides; Locomotion; Longevity; Oxidation-Reduction; Paraquat; Parkinson Disease; Phycocyanin; Spirulina; Superoxide Dismutase | 2017 |
Paraquat and maneb co-exposure induces noradrenergic locus coeruleus neurodegeneration through NADPH oxidase-mediated microglial activation.
Topics: Acetophenones; Adrenergic Neurons; Animals; Disease Models, Animal; Enzyme Inhibitors; Locus Coeruleus; Male; Maneb; Mice; Mice, Inbred C57BL; Microglia; NADPH Oxidases; Nerve Degeneration; Neurotoxicity Syndromes; NF-kappa B; Paraquat; Parkinson Disease; Risk Factors | 2017 |
[Change of endothelin-1 and nitrogen monoxide in rats with paraquat poisoning].
Topics: Animals; Disease Models, Animal; Endothelin-1; Male; Nitric Oxide; Paraquat; Rats; Rats, Sprague-Dawley | 2008 |
[Change of JNK and c-Jun in lung injury associated with paraquat poisoning of rats].
Topics: Acute Lung Injury; Animals; Disease Models, Animal; JNK Mitogen-Activated Protein Kinases; Lung; Male; Paraquat; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley | 2008 |
[Influence of pyrrolidine dithiocarbamate (PDTC) on expression of transforming growth factor beta(1), matrix metalloproteinase-2 and tissue inhibitor-1 of metalloproteinase in rats with pulmonary damage induced by paraquat].
Topics: Acute Lung Injury; Animals; Disease Models, Animal; Lung; Male; Matrix Metalloproteinase 2; Paraquat; Pyrrolidines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Thiocarbamates; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta1 | 2008 |
[Experimental study on therapeutic efficacy of tetrandrine on lung injury induced by acute of paraquat poisoning].
Topics: Acute Disease; Animals; Benzylisoquinolines; Disease Models, Animal; Glutathione Peroxidase; Lung; Lung Injury; Male; Malondialdehyde; Paraquat; Rats; Rats, Wistar; Superoxide Dismutase | 2008 |
Survival motor neuron deficiency enhances progression in an amyotrophic lateral sclerosis mouse model.
Topics: Amyotrophic Lateral Sclerosis; Animals; Cell Line; Cell Nucleus; Disease Models, Animal; Disease Progression; Female; Male; Mice; Mice, Knockout; Mice, Transgenic; Mutation, Missense; Neurons; Oxidants; Paraquat; RNA, Messenger; Spinal Cord; Superoxide Dismutase; Superoxide Dismutase-1; Survival of Motor Neuron 1 Protein | 2009 |
[Expression of inflammatory factors in lung tissue of acute paraquat poisoned rats].
Topics: Acute Disease; Animals; Disease Models, Animal; HMGB1 Protein; Interleukin-10; Lung; Male; Paraquat; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tumor Necrosis Factor-alpha | 2009 |
[Effects of ulinastatin to pro-inflammatory mediators in rats with acute paraquat intoxication].
Topics: Acute Disease; Animals; Disease Models, Animal; Female; Glycoproteins; Inflammation Mediators; Interleukin-1beta; Interleukin-2; Paraquat; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 2009 |
Quantification of Paraquat, MPTP, and MPP+ in brain tissue using microwave-assisted solvent extraction (MASE) and high-performance liquid chromatography-mass spectrometry.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Chromatography, High Pressure Liquid; Disease Models, Animal; Dopamine Agents; Estrogen Receptor alpha; Herbicides; Mice; Microwaves; Paraquat; Parkinson Disease; Piperidines; Pyrazoles; Solvents; Tandem Mass Spectrometry | 2009 |
Pyrrolidine dithiocarbamate attenuates paraquat-induced lung injury in rats.
Topics: Animals; Antioxidants; Cytokines; Disease Models, Animal; Humans; Lung Injury; Male; Paraquat; Pyrrolidines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Thiocarbamates; Treatment Outcome | 2009 |
Protective effects of a superoxide dismutase/catalase mimetic compound against paraquat pneumotoxicity in rat lung.
Topics: Animals; Antioxidants; Bronchoalveolar Lavage Fluid; Catalase; Disease Models, Animal; Herbicides; Lung; Male; Organometallic Compounds; Oxidative Stress; Paraquat; Rats; Rats, Wistar; Salicylates; Superoxide Dismutase | 2009 |
The effects of polyphenols on survival and locomotor activity in Drosophila melanogaster exposed to iron and paraquat.
Topics: Animals; Antioxidants; Disease Models, Animal; Drosophila melanogaster; Female; Ferric Compounds; Flavonoids; Motor Activity; Neuroprotective Agents; Oxidative Stress; Paraquat; Parkinson Disease; Phenols; Polyphenols; Survival Rate | 2010 |
Recruitment maneuver: RAMP versus CPAP pressure profile in a model of acute lung injury.
Topics: Acute Lung Injury; Analysis of Variance; Animals; Collagen Type III; Disease Models, Animal; Gene Expression Regulation; Lung; Lung Volume Measurements; Paraquat; Positive-Pressure Respiration; Rats; Rats, Wistar; Recruitment, Neurophysiological; Respiratory Mechanics; RNA, Messenger | 2009 |
Glycogen content is affected differently in acute pulmonary and extra-pulmonary lung injury.
Topics: Acute Lung Injury; Animals; Diaphragm; Disease Models, Animal; Glycogen; Herbicides; Injections, Intraperitoneal; Kidney; Lung; Male; Muscle, Skeletal; Myocardium; Organ Specificity; Paraquat; Rats; Rats, Wistar; Respiratory Distress Syndrome | 2009 |
[Expression of thrombomodulin, endothelial protein C receptor in lung tissue of acute paraquat poisoned rats and intervention of sodium dimercaptopropane sulfonate].
Topics: Animals; Antigens, CD; Disease Models, Animal; Lung; Male; Paraquat; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; RNA, Messenger; Thrombomodulin; Unithiol | 2009 |
[Change of oxidative stress and nuclear factor-kappa B in acute paraquat poisoned rats].
Topics: Animals; Disease Models, Animal; Lung; Male; NF-kappa B; Oxidative Stress; Paraquat; Rats; Rats, Sprague-Dawley | 2009 |
Glycogen synthase kinase 3β and its phosphorylated form (Y216) in the paraquat-induced model of parkinsonism.
Topics: Animals; Corpus Striatum; Disease Models, Animal; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Male; Mesencephalon; Motor Activity; Paraquat; Parkinsonian Disorders; Phosphorylation; Rats; Rats, Wistar; Substantia Nigra; Tyrosine | 2011 |
Caffeine protects against combined paraquat and maneb-induced dopaminergic neuron degeneration.
Topics: Animals; Caffeine; Cell Count; Chronic Disease; Disease Models, Animal; Dopamine; Drug Interactions; Fungicides, Industrial; Herbicides; Locomotion; Male; Maneb; Mice; Mice, Inbred C57BL; Nerve Degeneration; Neurons; Neuroprotective Agents; Paraquat; Substantia Nigra | 2010 |
Lysosomal degradation of alpha-synuclein in vivo.
Topics: alpha-Synuclein; Animals; Autophagy; Disease Models, Animal; Herbicides; HSC70 Heat-Shock Proteins; Humans; Lysosomal-Associated Membrane Protein 2; Lysosomes; Male; Mesencephalon; Mice; Mice, Transgenic; Neurons; Paraquat; Parkinson Disease | 2010 |
Role of growth factors in acute lung injury induced by paraquat in a rat model.
Topics: Acute Lung Injury; Animals; Cytokines; Disease Models, Animal; Gene Expression; Herbicides; Insulin-Like Growth Factor I; Intercellular Signaling Peptides and Proteins; Lung; Male; Paraquat; Platelet-Derived Growth Factor; Pulmonary Edema; Rats; Rats, Wistar; Transforming Growth Factor beta1 | 2011 |
Normal prion protein in Drosophila enhances the toxicity of pathogenic polyglutamine proteins and alters susceptibility to oxidative and autophagy signaling modulators.
Topics: Adenine; Animals; Animals, Genetically Modified; Autophagy; Disease Models, Animal; Dithiothreitol; Drosophila melanogaster; Eye; Lithium Chloride; Machado-Joseph Disease; Mice; Models, Genetic; Neurons; Oxidative Stress; Paraquat; Peptides; Prions; Unfolded Protein Response; Water | 2011 |
Therapeutic hypothermia attenuates acute lung injury in paraquat intoxication in rats.
Topics: Acute Lung Injury; Animals; Disease Models, Animal; Hypothermia, Induced; Male; Paraquat; Rats; Rats, Sprague-Dawley; Survival Rate; Treatment Outcome | 2011 |
Granulocyte macrophage-colony stimulating factor protects against substantia nigra dopaminergic cell loss in an environmental toxin model of Parkinson's disease.
Topics: Animals; Cell Death; Disease Models, Animal; Dopamine; Granulocyte-Macrophage Colony-Stimulating Factor; Herbicides; Injections, Intralesional; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Neurons; Neuroprotective Agents; Paraquat; Parkinsonian Disorders; Substantia Nigra | 2011 |
Complement inhibition alleviates paraquat-induced acute lung injury.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Antibodies, Monoclonal; Complement Activation; Complement C1q; Complement C3; Disease Models, Animal; Lung; Mice; Mice, Inbred C57BL; Mice, Knockout; Paraquat; Receptor, Anaphylatoxin C5a; Receptors, Complement; Recombinant Fusion Proteins; Signal Transduction; Time Factors | 2011 |
The role of calcium channel blockers and resveratrol in the prevention of paraquat-induced parkinsonism in Drosophila melanogaster: a locomotor analysis.
Topics: Animals; Antioxidants; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Disease Models, Animal; Dopamine; Drosophila melanogaster; Nerve Degeneration; Paraquat; Parkinsonian Disorders; Resveratrol; Stilbenes; Substantia Nigra | 2011 |
[The study of effects of pirfenidone on the pulmonary fibrosis induced by paraquat in mice].
Topics: Animals; Disease Models, Animal; Lung; Male; Mice; Mice, Inbred ICR; Paraquat; Pulmonary Fibrosis; Pyridones; Transforming Growth Factor beta | 2011 |
Apolipoprotein D mediates autocrine protection of astrocytes and controls their reactivity level, contributing to the functional maintenance of paraquat-challenged dopaminergic systems.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Apolipoproteins D; Apoptosis; Astrocytes; Brain; Cells, Cultured; Cerebral Cortex; Chromatography, High Pressure Liquid; Disease Models, Animal; Dopamine; Flow Cytometry; Gene Expression Regulation; Herbicides; Homovanillic Acid; Humans; Hypokinesia; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Neurons; Paraquat; Signal Transduction; Thiobarbituric Acid Reactive Substances | 2011 |
Differential effects of activating D1 and D2 receptors on electrophysiology of neostriatal neurons in a rat model of Parkinson's disease induced by paraquat and maneb.
Topics: Animals; Disease Models, Animal; Electrophysiological Phenomena; Fungicides, Industrial; Herbicides; Male; Maneb; Neocortex; Paraquat; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2 | 2011 |
Protective effect of ambroxol against paraquat-induced pulmonary fibrosis in rats.
Topics: Ambroxol; Animals; Collagen; Cytokines; Disease Models, Animal; Expectorants; Lung; Male; Oxidative Stress; Paraquat; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Treatment Outcome | 2011 |
[Pulmonary platelet endothelial cell adhesion molecule-1 (PECAM-1) in rabbits after acute paraquat (PQ) poisoning].
Topics: Animals; Disease Models, Animal; Female; Lung; Lung Injury; Male; Paraquat; Platelet Endothelial Cell Adhesion Molecule-1; Rabbits | 2011 |
Hypercholesterolemia and oxidative stress inhibit endothelial cell healing after arterial injury.
Topics: Acetylcysteine; Animals; Antioxidants; Biomarkers; Carotid Artery Injuries; Carotid Artery, Common; Cell Proliferation; Disease Models, Animal; Endothelial Cells; Hypercholesterolemia; Male; Mice; Mice, Inbred C57BL; Oxidants; Oxidative Stress; Paraquat; Time Factors; Wound Healing | 2012 |
Reactive oxygen species are not involved in the onset of age-related memory impairment in Drosophila.
Topics: Aging; Animals; Association Learning; Catalase; Disease Models, Animal; Drosophila; Drosophila Proteins; Heat-Shock Proteins; Herbicides; Hydrogen Peroxide; Memory Disorders; Mushroom Bodies; Oxidants; Oxidative Stress; Paraquat; Reactive Oxygen Species | 2012 |
Glutathione s-transferase omega 1 activity is sufficient to suppress neurodegeneration in a Drosophila model of Parkinson disease.
Topics: Animals; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins; Glutathione Transferase; Herbicides; JNK Mitogen-Activated Protein Kinases; Male; Mitochondrial Proton-Translocating ATPases; Mutagenesis, Site-Directed; Nerve Degeneration; Oxidative Stress; Paraquat; Parkinsonian Disorders; Phenotype; Signal Transduction; Tubulin; Ubiquitin-Protein Ligases; Unfolded Protein Response | 2012 |
Viral-toxin interactions and Parkinson's disease: poly I:C priming enhanced the neurodegenerative effects of paraquat.
Topics: Animals; Antiviral Agents; Corpus Striatum; Disease Models, Animal; Drug Synergism; Male; Mice; Mice, Inbred C57BL; Nerve Degeneration; Paraquat; Parkinsonian Disorders; Poly I-C | 2012 |
Oxidative stress contributes to outcome severity in a Drosophila melanogaster model of classic galactosemia.
Topics: Animals; Antioxidants; Ascorbic Acid; Cysteine; Dimethyl Sulfoxide; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins; Galactose; Galactosemias; Galactosephosphates; Gene Expression; Gene Knockout Techniques; Genes, Insect; Glutathione; Glutathione Transferase; Humans; Mutation; Oxidative Stress; Paraquat; Reactive Oxygen Species; UDPglucose-Hexose-1-Phosphate Uridylyltransferase; Xanthones | 2013 |
[Experimental anticoagulant therapy of acute lung injury induced by paraquat].
Topics: Acute Lung Injury; Animals; Anticoagulants; Aspirin; Disease Models, Animal; Drug Therapy, Combination; Heparin, Low-Molecular-Weight; Male; Paraquat; Rats; Rats, Wistar | 2012 |
[The experimental study of therapeutical effects of KANGFUXINYE on upper gastrointestinal injury induced by paraquat in rats].
Topics: Animals; Biological Products; Disease Models, Animal; Gastrointestinal Diseases; Lipid Peroxidation; Male; Malondialdehyde; Paraquat; Rats; Rats, Wistar; Superoxide Dismutase | 2012 |
Effect of pirfenidone on pulmonary fibrosis due to paraquat poisoning in rats.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Ascorbic Acid; Disease Models, Animal; Herbicides; Injections, Intraperitoneal; Injections, Intravenous; Life Expectancy; Male; Paraquat; Pulmonary Fibrosis; Pyridones; Rats; Rats, Wistar; Survival Rate; Vitamin E | 2012 |
Combined exposure to Maneb and Paraquat alters transcriptional regulation of neurogenesis-related genes in mice models of Parkinson's disease.
Topics: alpha-Synuclein; Animals; Disease Models, Animal; Gene Expression Regulation; Gene-Environment Interaction; Hippocampus; Humans; Immunohistochemistry; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Maneb; Mice; Mice, Transgenic; Neurogenesis; Paraquat; Parkinson Disease; Pesticides; Protein Serine-Threonine Kinases; Real-Time Polymerase Chain Reaction; Transcription, Genetic | 2012 |
Low doses of paraquat and polyphenols prolong life span and locomotor activity in knock-down parkin Drosophila melanogaster exposed to oxidative stress stimuli: implication in autosomal recessive juvenile parkinsonism.
Topics: Animals; Animals, Genetically Modified; Antioxidants; Disease Models, Animal; Dopaminergic Neurons; Drosophila melanogaster; Drosophila Proteins; Gene Knockdown Techniques; Herbicides; Humans; Longevity; Motor Activity; Oxidative Stress; Paraquat; Parkinsonian Disorders; Polyphenols; Ubiquitin-Protein Ligases | 2013 |
Paraquat-induced pulmonary fibrosis starts at an early stage of inflammation in rats.
Topics: Actins; Animals; Bronchoalveolar Lavage Fluid; Collagen Type III; Disease Models, Animal; Disease Progression; Herbicides; Humans; Inflammation; Lung; Male; Paraquat; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley | 2012 |
Central nervous system damage due to acute paraquat poisoning: an experimental study with rat model.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antigens, Nuclear; Apoptosis; Astrocytes; Biomarkers; Brain; Brain Edema; Deoxyguanosine; Disease Models, Animal; Fluorescent Antibody Technique; Herbicides; Lipid Peroxidation; Microglia; Microscopy, Confocal; Microscopy, Electron, Transmission; Nerve Tissue Proteins; Neurons; Neurotoxicity Syndromes; Oxidative Stress; Paraquat; Rats; Rats, Sprague-Dawley; Time Factors | 2013 |
Paraquat-induced retinal degeneration is exaggerated in CX3CR1-deficient mice and is associated with increased retinal inflammation.
Topics: Animals; CX3C Chemokine Receptor 1; Disease Models, Animal; DNA; Fluorescein Angiography; Fundus Oculi; Gene Expression Regulation; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Microscopy, Electron, Transmission; Oxidative Stress; Paraquat; Real-Time Polymerase Chain Reaction; Receptors, Chemokine; Retina; Retinal Degeneration; Retinitis; Signal Transduction | 2013 |
Drosophila Trap1 protects against mitochondrial dysfunction in a PINK1/parkin model of Parkinson's disease.
Topics: Animals; Animals, Genetically Modified; Disease Models, Animal; Dopamine; Drosophila; Drosophila Proteins; Herbicides; HSP90 Heat-Shock Proteins; Mitochondria; Mutation; Oxidative Stress; Paraquat; Parkinson Disease; Protein Serine-Threonine Kinases; PTEN Phosphohydrolase; TNF Receptor-Associated Factor 1; Ubiquitin-Protein Ligases | 2013 |
Lung function and airway inflammation in rats following exposure to combustion products of carbon-graphite/epoxy composite material: comparison to a rodent model of acute lung injury.
Topics: Animals; Bronchoalveolar Lavage Fluid; Chemokine CXCL2; Disease Models, Animal; Epoxy Compounds; Graphite; Herbicides; Histocytochemistry; Interferon-gamma; Male; Monokines; Paraquat; Pneumonia; Random Allocation; Rats; Rats, Inbred F344; Respiratory Distress Syndrome; Respiratory Function Tests; Smoke; Smoke Inhalation Injury; Tumor Necrosis Factor-alpha | 2003 |
Cell type-specific hypersensitivity to oxidative damage in CSB and XPA mice.
Topics: Animals; Cockayne Syndrome; Disease Models, Animal; DNA Damage; DNA Repair; Gamma Rays; Mice; Oxidative Stress; Paraquat; X-Rays; Xeroderma Pigmentosum | 2003 |
Effects of L-dopa and other amino acids against paraquat-induced nigrostriatal degeneration.
Topics: Amino Acids; Animals; Corpus Striatum; Disease Models, Animal; Levodopa; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Paraquat; Parkinson Disease, Secondary; Substantia Nigra; Tyrosine 3-Monooxygenase | 2003 |
Differential heat shock gene hsp70-1 response to toxicants revealed by in vivo study of lungs in transgenic mice.
Topics: Air Pollutants; Animals; Cadmium; Disease Models, Animal; Female; Gene Expression Regulation; Heat-Shock Response; HSP70 Heat-Shock Proteins; Luciferases; Lung; Male; Mice; Mice, Transgenic; Oxidative Stress; Ozone; Paraquat; Parathion; Promoter Regions, Genetic; Protozoan Proteins; Respiratory Mucosa; Stress, Physiological; Toxins, Biological | 2002 |
Inducible superoxide dismutase 1 aggregation in transgenic amyotrophic lateral sclerosis mouse fibroblasts.
Topics: Acetylcysteine; Amyotrophic Lateral Sclerosis; Animals; Animals, Newborn; Blotting, Western; Cell Survival; Chelating Agents; Chlorides; Copper; Detergents; Disease Models, Animal; Ditiocarb; Fibroblasts; Humans; Immunohistochemistry; Mice; Mice, Transgenic; Minocycline; Mutation; Oxidative Stress; Paraquat; Peroxynitrous Acid; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Binding; Solubility; Spinal Cord; Superoxide Dismutase; Superoxide Dismutase-1; Zinc Compounds | 2004 |
Chymase is activated in the pulmonary inflammation and fibrosis induced by paraquat in hamsters.
Topics: Animals; Chymases; Cricetinae; Disease Models, Animal; Enzyme Activation; Herbicides; Male; Paraquat; Peptidyl-Dipeptidase A; Pneumonia; Pulmonary Fibrosis; Serine Endopeptidases; Toxicity Tests, Acute; Toxicity Tests, Chronic | 2004 |
Paraquat induces selective dopaminergic nigrostriatal degeneration in aging C57BL/6 mice.
Topics: Aging; Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Male; Mice; Mice, Inbred C57BL; Motor Activity; Paraquat; Parkinson Disease, Secondary; Substantia Nigra; Tyrosine 3-Monooxygenase | 2005 |
The Helicobacter pylori MutS protein confers protection from oxidative DNA damage.
Topics: Animals; Disease Models, Animal; DNA; DNA Damage; Electrophoretic Mobility Shift Assay; Gene Deletion; Guanine; Helicobacter Infections; Helicobacter pylori; Hydrogen Peroxide; Mice; Mice, Inbred C57BL; Mutagenesis, Insertional; MutS DNA Mismatch-Binding Protein; Oxidants; Oxidation-Reduction; Oxygen; Paraquat; Protein Binding | 2005 |
Transforming growth factor-beta1 upregulation is independent of angiotensin in paraquat-induced lung fibrosis.
Topics: Actins; Angiotensin II; Animals; Collagen Type I; Collagen Type III; Disease Models, Animal; Hydroxyproline; Lung; Male; Microscopy, Polarization; Paraquat; Peptidyl-Dipeptidase A; Proto-Oncogene Proteins c-myc; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; RNA, Messenger; Time Factors; Toxicity Tests; Transforming Growth Factor beta; Transforming Growth Factor beta1; Up-Regulation | 2005 |
Effects of prenatal paraquat and mancozeb exposure on amino acid synaptic transmission in developing mouse cerebellar cortex.
Topics: Animals; Aspartic Acid; Cerebellar Cortex; Disease Models, Animal; Down-Regulation; Female; Fungicides, Industrial; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Herbicides; Hyperkinesis; Maneb; Mice; Motor Activity; Neural Inhibition; Paraquat; Pregnancy; Prenatal Exposure Delayed Effects; Synaptic Transmission; Zineb | 2005 |
Similar patterns of mitochondrial vulnerability and rescue induced by genetic modification of alpha-synuclein, parkin, and DJ-1 in Caenorhabditis elegans.
Topics: 3-Hydroxybutyric Acid; alpha-Synuclein; Amino Acid Sequence; Animals; Animals, Genetically Modified; Antioxidants; Apoptosis; Benzoates; Benzothiazoles; Bile Acids and Salts; Caenorhabditis elegans; Cholagogues and Choleretics; Copper; Disease Models, Animal; Electron Transport Complex I; Gene Deletion; Gene Expression Regulation; Gene Library; Genetic Techniques; Humans; Immunoblotting; Intracellular Signaling Peptides and Proteins; Ions; Iron; Mitochondria; Molecular Sequence Data; Mutagenesis; Mutation; Neurons; Oncogene Proteins; Oxygen Consumption; Paraquat; Parkinson Disease; Polyenes; Probucol; Protein Deglycase DJ-1; Pyrazoles; Pyridazines; RNA, Small Interfering; Rotenone; Sequence Homology, Amino Acid; Sodium Azide; Taurochenodeoxycholic Acid; Thiazoles; Time Factors; Transgenes; Ubiquitin-Protein Ligases | 2005 |
Systemic exposure to paraquat and maneb models early Parkinson's disease in young adult rats.
Topics: Age of Onset; Animals; Cells, Cultured; Coculture Techniques; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Encephalitis; Fungicides, Industrial; Gliosis; Herbicides; Male; Maneb; Microglia; Nerve Degeneration; Neurons; Paraquat; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Rats, Wistar; Substantia Nigra | 2005 |
[Effects of different doses of levodopa on paraquat-induced neurotoxicity: an experiment with mice].
Topics: alpha-Synuclein; Animals; Blood-Brain Barrier; Disease Models, Animal; Dose-Response Relationship, Drug; Levodopa; Male; Mice; Mice, Inbred C57BL; Neurons; Paraquat; Substantia Nigra; Tyrosine 3-Monooxygenase | 2005 |
Status of antioxidant defense system and expression of toxicant responsive genes in striatum of maneb- and paraquat-induced Parkinson's disease phenotype in mouse: mechanism of neurodegeneration.
Topics: Analysis of Variance; Animals; Catalase; Corpus Striatum; Cytochrome P-450 CYP2E1; Disease Models, Animal; Gene Expression; Glutathione Transferase; Herbicides; Lipid Peroxidation; Male; Maneb; Mice; Paraquat; Parkinson Disease; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Superoxide Dismutase; Time Factors | 2006 |
Degeneration of dopaminergic mesocortical neurons and activation of compensatory processes induced by a long-term paraquat administration in rats: implications for Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Cerebral Cortex; Chromatography, High Pressure Liquid; Disease Models, Animal; Dopamine; Herbicides; Homovanillic Acid; Immunohistochemistry; Male; Nerve Degeneration; Neurons; Paraquat; Parkinsonian Disorders; Rats; Rats, Wistar; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 2006 |
PEP-1-SOD fusion protein efficiently protects against paraquat-induced dopaminergic neuron damage in a Parkinson disease mouse model.
Topics: alpha-Synuclein; Animals; Astrocytes; Cells, Cultured; Disease Models, Animal; Dopamine Agents; Enzyme Stability; Gene Expression; HSP70 Heat-Shock Proteins; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Neurons; Oxidative Stress; Paraquat; Parkinson Disease; Recombinant Fusion Proteins; Serine Endopeptidases; Superoxide Dismutase | 2006 |
Oxidative stress mediates tau-induced neurodegeneration in Drosophila.
Topics: Alzheimer Disease; Animals; Disease Models, Animal; Drosophila; Humans; Nerve Degeneration; Oxidative Stress; Paraquat; tau Proteins; Tauopathies; Vitamin E | 2007 |
Mouse model of paraquat-poisoned lungs and its gene expression profile.
Topics: Administration, Intranasal; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression; Gene Expression Profiling; Genetic Markers; Herbicides; Lung; Mice; Mice, Inbred C57BL; Paraquat; Pulmonary Fibrosis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2007 |
Nicotine partially protects against paraquat-induced nigrostriatal damage in mice; link to alpha6beta2* nAChRs.
Topics: Analysis of Variance; Animals; Autoradiography; Brain Injuries; Bridged Bicyclo Compounds, Heterocyclic; Cell Count; Conotoxins; Corpus Striatum; Disease Models, Animal; Dopamine; Drug Interactions; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Paraquat; Protein Binding; Pyridines; Receptors, Nicotinic; Substantia Nigra | 2007 |
Interaction of genetic and environmental factors in a Drosophila parkinsonism model.
Topics: Animals; Biopterins; Catalase; Cell Aggregation; Disease Models, Animal; Dopamine; Drosophila; Drosophila Proteins; Dyskinesia, Drug-Induced; Female; Gene Expression Regulation; Genetic Predisposition to Disease; Hazardous Substances; Herbicides; Homeostasis; Longevity; Male; Mutation; Neurons; Paraquat; Parkinsonian Disorders | 2007 |
[Changes of serum cytokine caused by acute paraquat poisoning].
Topics: Acute Disease; Animals; Cytokines; Disease Models, Animal; Female; Interleukin-10; Interleukin-1beta; Interleukin-6; Male; Paraquat; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 2007 |
An antisense oligonucleotide to HSP47 inhibits paraquat-induced pulmonary fibrosis in rats.
Topics: Animals; Antifibrinolytic Agents; Disease Models, Animal; Drug Therapy, Combination; Herbicides; HSP47 Heat-Shock Proteins; Hydroxyproline; Immunoenzyme Techniques; Intubation, Intratracheal; Lung; Male; Oligonucleotides, Antisense; Paraquat; Pulmonary Fibrosis; Rats; Rats, Wistar | 2007 |
Anti-TGF-beta1 antibody: an effective treatment for lung injury caused by paraquat in the future.
Topics: Animals; Antibodies; Disease Models, Animal; Lung; Lung Injury; Paraquat; Rats; Rats, Wistar; Transforming Growth Factor beta1 | 2008 |
Behavioral and histopathological consequences of paraquat intoxication in mice: effects of alpha-synuclein over-expression.
Topics: alpha-Synuclein; Analysis of Variance; Animals; Behavior, Animal; Cell Count; Disease Models, Animal; Gene Expression Regulation; Humans; Locus Coeruleus; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Neurons; Neurotoxicity Syndromes; Paraquat; Psychomotor Performance; Substantia Nigra; Tyrosine 3-Monooxygenase | 2007 |
Chronic inhalation of rotenone or paraquat does not induce Parkinson's disease symptoms in mice or rats.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Administration, Inhalation; Administration, Intranasal; Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Drug Administration Schedule; Herbicides; Insecticides; Male; Mice; Mice, Inbred C57BL; Motor Activity; Nerve Degeneration; Neurons; Paraquat; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Rotenone; Substantia Nigra | 2007 |
Paraquat: the red herring of Parkinson's disease research.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Disease Models, Animal; Humans; Molecular Structure; Oxidative Stress; Paraquat; Parkinsonian Disorders; Reproducibility of Results; Structure-Activity Relationship | 2007 |
Prolonged toxicokinetics and toxicodynamics of paraquat in mouse brain.
Topics: Administration, Oral; Animals; Brain; Disease Models, Animal; Half-Life; Herbicides; Injections, Intramuscular; Lipid Peroxidation; Male; Mice; Paraquat; Parkinson Disease, Secondary; Proteasome Endopeptidase Complex | 2007 |
[Changes of p38 MAPK and nuclear factor-kappa B in lung tissue of acute paraquat poisoned rats].
Topics: Acute Lung Injury; Animals; Disease Models, Animal; Female; Lung; Male; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Paraquat; Phosphorylation; Rats; Rats, Sprague-Dawley | 2007 |
[Increased expression of placenta growth factor in lung tissue of paraquat-induced rat pulmonary fibrosis model].
Topics: Animals; Disease Models, Animal; Female; Hydroxyproline; Lung; Paraquat; Placenta Growth Factor; Pregnancy Proteins; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2007 |
[Effects of high dose ambroxol on lung injury induced by paraquat in rats].
Topics: Acute Lung Injury; Ambroxol; Animals; Disease Models, Animal; Lung; Male; Oxidative Stress; Paraquat; Rats; Rats, Sprague-Dawley | 2007 |
Enhanced autophagy and mitochondrial aberrations in murine G(M1)-gangliosidosis.
Topics: Adenine; Adenosine Triphosphate; Animals; Apoptosis Regulatory Proteins; Astrocytes; Autophagy; Beclin-1; beta-Galactosidase; Brain; Cells, Cultured; Disease Models, Animal; Electron Transport Complex IV; Enzyme Inhibitors; G(M1) Ganglioside; Gangliosidosis, GM1; Lysosomes; Mice; Mice, Knockout; Microtubule-Associated Proteins; Mitochondria; Paraquat; Protein Kinases; Proteins; Signal Transduction; TOR Serine-Threonine Kinases | 2008 |
Novel and extensive aspects of paraquat-induced pulmonary fibrogenesis: comparative and time-course microarray analyses in fibrogenic and non-fibrogenic rats.
Topics: Animals; Apoptosis; bcl-Associated Death Protein; Body Weight; Cluster Analysis; Collagen; Disease Models, Animal; Gene Expression Profiling; Hydroxyproline; Lung; Male; Oligonucleotide Array Sequence Analysis; Organ Size; Paraquat; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Time Factors; Transforming Growth Factors | 2007 |
Gene expression profiles of mouse striatum in control and maneb + paraquat-induced Parkinson's disease phenotype: validation of differentially expressed energy metabolizing transcripts.
Topics: Animals; Blotting, Western; Corpus Striatum; Disease Models, Animal; Energy Metabolism; Fungicides, Industrial; Gene Expression Profiling; Herbicides; Male; Maneb; Mice; Oligonucleotide Array Sequence Analysis; Paraquat; Phenotype; RNA, Messenger | 2008 |
Pulmonary fibrosis in experimental acute respiratory disease.
Topics: Acute Disease; Animals; Bleomycin; Collagen; Disease Models, Animal; Lung Diseases; Male; Ozone; Paraquat; Pulmonary Fibrosis; Rats; Respiratory Distress Syndrome | 1981 |
[Experimental study on paraquat-induced pneumonitis--therapeutic effects of prednisolone and elastase].
Topics: Animals; Disease Models, Animal; Drug Evaluation; Male; Pancreatic Elastase; Paraquat; Prednisolone; Pulmonary Fibrosis; Rats; Rats, Inbred Strains | 1983 |
[Changes in the lung tissue of newborn rats after paraquat as a model of respiratory distress].
Topics: Animals; Animals, Newborn; Disease Models, Animal; Humans; Infant, Newborn; Lung; Paraquat; Rats; Rats, Inbred Strains; Respiratory Distress Syndrome, Newborn | 1984 |
[Lung changes after paraquat as an experimental model of the respiratory distress in the newborn and diffuse interstitial fibrosis of the lung].
Topics: Animals; Disease Models, Animal; Female; Humans; Infant, Newborn; Lung; Male; Paraquat; Pulmonary Fibrosis; Rats; Respiratory Distress Syndrome, Newborn | 1981 |
[Experimental models of lung diseases pulmonary fibrosis (idiopathic interstitial pneumonia) (author's transl)].
Topics: Animals; Blood Sedimentation; Disease Models, Animal; Dogs; Leukocyte Count; Paraquat; Pulmonary Alveoli; Pulmonary Fibrosis; Respiratory Function Tests | 1981 |
Liposomal alpha-tocopherol alleviates the progression of paraquat-induced lung damage.
Topics: Alkaline Phosphatase; Animals; Body Weight; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Environmental Exposure; Glutathione; Injections, Intraperitoneal; Lipid Peroxidation; Liposomes; Lung; Lung Diseases; Male; Organ Size; Paraquat; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Vitamin E | 1995 |
Comparison of effects of margarite extract and recombinant human superoxide dismutase on paraquat-induced superoxide anion radicals in rat lung.
Topics: Animals; Anions; Chromatography, High Pressure Liquid; Disease Models, Animal; Electrophoresis; Female; Lung Diseases; Male; Paraquat; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Superoxide Dismutase; Superoxides | 1994 |
Immunohistochemical localization and dynamics of paraquat in the stomach and esophagus of rats.
Topics: Animals; Disease Models, Animal; Esophagus; Evaluation Studies as Topic; Forensic Medicine; Immunohistochemistry; Male; Paraquat; Poisoning; Rats; Rats, Sprague-Dawley; Solubility; Stomach; Time Factors; Tissue Distribution | 1993 |
Airspace configuration at different transpulmonary pressures in normal and paraquat-induced lung injury in rats.
Topics: Air Pressure; Analysis of Variance; Animals; Disease Models, Animal; Herbicides; Inhalation; Paraquat; Plethysmography; Positive-Pressure Respiration; Pulmonary Alveoli; Pulmonary Gas Exchange; Rats; Rats, Wistar; Respiration; Respiratory Distress Syndrome; Respiratory Mechanics | 1998 |
No significant paraquat-induced oxidative DNA damage in rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Deoxyguanosine; Disease Models, Animal; DNA Damage; Herbicides; Liver; Lung; Male; Paraquat; Rats; Rats, Wistar; Reactive Oxygen Species | 2000 |
Attenuation of paraquat-induced dopaminergic toxicity on the substantia nigra by (-)-deprenyl in vivo.
Topics: Animals; Apomorphine; Behavior, Animal; Chromatography, High Pressure Liquid; Disease Models, Animal; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Interactions; Herbicides; Male; Neuroprotective Agents; Paraquat; Rats; Rats, Wistar; Selegiline; Stereotyped Behavior; Substantia Nigra | 2001 |
Serum SP-D is a marker of lung injury in rats.
Topics: Animals; Antimetabolites, Antineoplastic; Biomarkers; Bleomycin; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Fibroblast Growth Factor 7; Fibroblast Growth Factors; Gene Expression; Glycoproteins; Herbicides; Hydrochloric Acid; Hyperplasia; Instillation, Drug; Lung Diseases; Male; Oxygen; Paraquat; Pulmonary Alveoli; Pulmonary Surfactant-Associated Protein D; Pulmonary Surfactants; Rats; Rats, Inbred F344; RNA, Messenger; Specific Pathogen-Free Organisms | 2002 |
Captopril inhibits the pulmonary toxicity of paraquat in rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Disease Models, Animal; Drug Combinations; Glutathione; Glutathione Peroxidase; Hydroxyproline; Lipid Peroxidation; Lung; Male; Paraquat; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2001 |
Essential role of ferritin Pfr in Helicobacter pylori iron metabolism and gastric colonization.
Topics: Animals; Bacterial Proteins; Biological Transport; Cation Transport Proteins; Disease Models, Animal; Ferritins; Gerbillinae; Helicobacter Infections; Helicobacter pylori; Hydrogen-Ion Concentration; Iron; Mutagenesis; Oxidative Stress; Paraquat; Repressor Proteins; Stomach; Superoxides | 2002 |
Changes in transglutaminase activity in an experimental model of pulmonary fibrosis induced by paraquat.
Topics: Animals; Collagen; Disease Models, Animal; DNA; Female; gamma-Glutamyltransferase; Hydroxyproline; Lung; Paraquat; Procollagen-Proline Dioxygenase; Pulmonary Fibrosis; Rats; Subcellular Fractions; Thymidine | 1979 |
Pulmonary interstitial fibrosis from paraquat in the hamster.
Topics: Adrenocorticotropic Hormone; Animals; Body Weight; Cricetinae; Disease Models, Animal; Freund's Adjuvant; Injections; Male; Paraquat; Pulmonary Fibrosis | 1975 |
Models of pulmonary fibrosis: misadventures and ramifications.
Topics: Aerosols; Animals; Antigens; Disease Models, Animal; Hypersensitivity, Delayed; Immunoglobulin A, Secretory; Lung; Macrophages; Ovalbumin; Paraquat; Pulmonary Fibrosis; Rabbits | 1979 |
Changes in the pulmonary uptake and binding of drugs in an experimental model of lung fibrosis.
Topics: Animals; Dexamethasone; Disease Models, Animal; Isoniazid; Lung; Male; Paraquat; Penicillin G; Pulmonary Fibrosis; Rats | 1979 |
[Report of the 40th meeting of the work group on the pathophysiology of breathing of the Society for Pathophysiology and the Society for Bronchopneumonology and Tuberculosis of the DDR. Animal experimental models of acute and chronic lung diseases].
Topics: Acute Disease; Animals; Asthma; Chronic Disease; Disease Models, Animal; Disseminated Intravascular Coagulation; Guinea Pigs; Lung Diseases; Paraquat; Pneumonia, Aspiration; Pulmonary Surfactants; Rabbits; Rats; Respiration, Artificial; Shock; Swine; Thiocyanates | 1978 |
[Experimental model of pulmonary fibrosis in the rat using paraquat injection].
Topics: Animals; Disease Models, Animal; Injections, Intraperitoneal; Male; Paraquat; Pulmonary Fibrosis; Rats; Time Factors | 1975 |
Taurine protection of lungs in hamster models of oxidant injury: a morphologic time study of paraquat and bleomycin treatment.
Topics: Animals; Antioxidants; Bleomycin; Cricetinae; Diet; Disease Models, Animal; Fresh Water; Lung Diseases; Male; Mesocricetus; Paraquat; Taurine | 1992 |
[Morphological evidence of the possible role of cytochrome P-450 in the development of an autoimmune process in the liver].
Topics: Animals; Autoimmune Diseases; Cytochrome P-450 Enzyme System; Disease Models, Animal; Immunohistochemistry; Lipid Peroxidation; Liver; Liver Diseases; Male; Microscopy, Electron; Paraquat; Rats | 1991 |
A new model of diffuse interstitial pulmonary fibrosis in the rat.
Topics: Animals; Bleomycin; Collagen; Disease Models, Animal; Lung; Male; Oxygen; Paraquat; Pulmonary Fibrosis; Rats; Rats, Inbred Strains | 1985 |
[Lung changes in rats under the action of paraquat and the importance of antioxidants].
Topics: Animals; Antioxidants; Disease Models, Animal; Drug Evaluation, Preclinical; Lung; Paraquat; Pulmonary Atelectasis; Pulmonary Fibrosis; Rats; Rats, Inbred Strains; Tuberculosis, Pulmonary | 1989 |
Experimental pulmonary fibrosis induced by paraquat plus oxygen in rats: a morphologic and biochemical sequential study.
Topics: Animals; Collagen; Disease Models, Animal; Lung; Male; Microscopy, Electron; Oxygen; Paraquat; Pulmonary Fibrosis; Rats; Rats, Inbred Strains | 1989 |
The ratio of oxidized/reduced glutathione as an index of oxidative stress in various experimental models of shock syndrome.
Topics: Animals; Animals, Newborn; Coronary Disease; Disease Models, Animal; Glutathione; Glutathione Disulfide; Oxidation-Reduction; Paraquat; Rats; Reference Values; Shock; Shock, Hemorrhagic; Shock, Septic; Swine | 1989 |
Pulmonary elastic fiber degradation in paraquat toxicity. An electron microscopic immunohistochemical study.
Topics: Animals; Disease Models, Animal; Elastin; Immunohistochemistry; Lung; Macaca fascicularis; Microscopy, Electron; Paraquat; Pulmonary Fibrosis | 1988 |
Pulmonary dysfunction during paraquat-induced lung injury: a model of acute alveolar injury.
Topics: Animals; Disease Models, Animal; Dogs; Lung; Lung Compliance; Lung Volume Measurements; Paraquat; Pulmonary Alveoli; Pulmonary Gas Exchange; Respiratory Insufficiency | 1985 |
Increased plasma paraquat levels in intoxicated mice following antiparaquat F(ab')2 treatment.
Topics: Animals; Disease Models, Animal; Immunization, Passive; Immunoglobulin Fab Fragments; Male; Mice; Mice, Inbred C57BL; Paraquat | 1985 |
Pulmonary effects of the herbicide paraquat studied 3 days after injection in rats.
Topics: Animals; Body Weight; Disease Models, Animal; Female; Lipid Metabolism; Lung; Organ Size; Paraquat; Phosphatidylcholines; Pulmonary Atelectasis; Pulmonary Surfactants; Rats; Respiration; Therapeutic Irrigation | 1973 |
Toxic effects of the herbicide paraquat.
Topics: Administration, Oral; Adult; Animals; Burns, Chemical; Child, Preschool; Disease Models, Animal; Epithelial Cells; Epithelium; Humans; Intestinal Absorption; Lethal Dose 50; Lung; Microscopy, Electron; Paraquat; Pulmonary Alveoli; Pulmonary Edema; Pulmonary Fibrosis; Rats; Skin Absorption | 1974 |
Paraquat poisoning as an experimental model of idiopathic respiratory distress.
Topics: Animals; Disease Models, Animal; Female; Herbicides; Humans; Infant, Newborn; Lung; Paraquat; Pyridinium Compounds; Rats; Respiratory Distress Syndrome, Newborn | 1970 |
Experimental respiratory distress induced by paraquat.
Topics: Animals; Disease Models, Animal; Female; Herbicides; Humans; Infant, Newborn; Inflammation; Lung; Lung Diseases; Paraquat; Pulmonary Alveoli; Pulmonary Surfactants; Pyridinium Compounds; Rats; Respiratory Distress Syndrome, Newborn; Respiratory Insufficiency; Surface Tension | 1971 |