paraquat has been researched along with Aging in 76 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 5 (6.58) | 18.7374 |
1990's | 11 (14.47) | 18.2507 |
2000's | 32 (42.11) | 29.6817 |
2010's | 25 (32.89) | 24.3611 |
2020's | 3 (3.95) | 2.80 |
Authors | Studies |
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Chen, X; Du, M; Qiu, W; Tian, Y; Wang, S; Wu, D | 1 |
Li, L; Liu, D; Ou, ZL; Zeng, X | 1 |
Eremina, S; Gautier, L; Gusarov, I; Katkova-Zhukotskaya, O; Makarov, AА; Mironov, A; Nudler, E; Pani, B; Shamovsky, I | 1 |
Aravind, L; Bonkowski, MS; Gorbunova, V; Hubbard, BP; Li, J; Ling, AJ; Lou, Z; Moniot, S; Qin, B; Rajman, LA; Sinclair, DA; Steegborn, C; Zhang, D | 1 |
Guan, S; Guo, Y; Sui, T; Wang, L; Wang, M; Wang, Q; Xu, J; Zhang, R; Zhang, Y | 1 |
Chen, W; Cuong, VT; Fei, J; Li, J; Shi, J; Wang, N; Yang, H; Yang, P; Yang, S; Zhang, M | 1 |
Degtyareva, NP; Doetsch, PW; Gordenin, DA; Klimczak, LJ; Placentra, VC; Saini, N; Sterling, JF | 1 |
Furuhata, R; Komata, Y; Morioka, H; Nishio, R; Takeda, A; Tamano, H | 1 |
Cai, DQ; Chang, ZS; Huang, R; Jiang, FQ; Kim, SK; Li, J; Liang, CQ; Park, KS; Peng, WT; Qi, XF; Song, GH; Wu, HY; Xia, JB; Zhao, H; Zheng, L | 1 |
Correnti, C; Ganfornina, MD; Ruiz, M; Sanchez, D; Strong, RK | 1 |
Abdin, MZ; Chaouhan, HS; Kar Chowdhuri, D; Patel, DK; Pragya, P; Shukla, AK | 1 |
Artan, M; Chang, HW; Hwang, AB; Kabir, MH; Kim, S; Lee, C; Lee, D; Lee, SJ; Lee, SS; Mair, WB; Nam, HJ; Ryu, EA; Yang, JS | 1 |
Babu, V; Benzing, T; Castells-Roca, L; Ermolaeva, MA; Frommolt, P; Greiss, S; Mueller, MM; Müller, RU; Schermer, B; Schneider, JI; Schumacher, B; Williams, AB | 1 |
Liu, R; Liu, Y; Pulliam, DA; Salmon, AB | 1 |
Huang, Y; Huang, Z; Jia, W; Li, H; Li, S; Liang, M; Ma, CW; Mao, X; Qin, C; Wang, Q; Zou, Y | 1 |
Bernard, K; Breton, L; Cacho-Valadez, B; Desjardins, D; Hekimi, S; Khaki, A; Liu, JL; Wang, Y; Yee, C | 1 |
Huang, M; Lou, D; Wang, Q; Zhou, Z | 1 |
Ackerson, LC; Cely, I; Chesselet, MF; De La Rosa, K; Gabby, L; Maidment, NT; McDowell, KA; Mortazavi, F; Mulligan, CK; Murphy, NP; Richter, F; Sioshansi, PC; Tsan, L | 1 |
Chen, C; Li, X; Li, Y; Lv, Z; Meng, J; Qiao, X; Zhang, Y | 1 |
Franzoso, G; Liu, B; Neufeld, AH; Papa, S; Suyeoka, G | 1 |
Lublin, AL; Mobbs, CV; Patel, HB; Yen, K | 1 |
Bokov, AF; Khodr, C; Lindsey, ML; Richardson, A; Sabia, MR | 1 |
Chan, D; Cookson, M; Ferree, A; Ghosh, J; Goldstein, L; Guillily, MD; Hisamoto, N; Hsu, CH; Iwatsubo, T; Kuwahara, T; Lanceta, J; Matsumoto, K; Moore, L; Raghavan, K; Saha, S; Segal, L; Wolozin, B | 1 |
Burns, JG; Mery, F | 1 |
Kim, YS; Park, JS; Yoo, MA | 1 |
Fan, H; Guan, S; Huang, L; Li, P; Li, W; Li, Y; Luo, J; Wang, G; Wang, L; Zhu, L | 1 |
Cho, SC; Cho, Y; Choi, JM; Hyun, S; Keam, B; Lee, J; Park, MC; Park, SC | 1 |
Andersen, JK; Oo, ML; Peng, J | 1 |
Claycomb, WC; Giuliani, A; Martinez, C; Pazienza, V; Rosenthal, N; Santini, MP; Vinciguerra, M | 1 |
Hirano, Y; Horiuchi, J; Kuriyama, Y; Miyashita, T; Saitoe, M | 1 |
Golubovskiĭ, MD; Kandalintseva, NV; Men'shchikova, EB; Vaĭsman, NIa; Zenkov, NK | 1 |
Bach, A; Clement, MH; Lin, L; Rakariyatham, K; Rangel, NA; Srinivasan, C; Trinh, K | 1 |
Kim, SK; Sagi, D | 1 |
Arking, R; Hwangbo, DS; Lane, M; Novoseltsev, V; Novoseltseva, J | 1 |
Baggs, RB; Cory-Slechta, DA; Goodman, BM; Richfield, EK; Thiruchelvam, M | 1 |
Edwards, MG; Klopp, R; Morrow, JD; Prolla, TA; Sarkar, D; Weindruch, R | 2 |
Driver, C; Georgeou, A | 1 |
Baggs, RB; Cory-Slechta, DA; Di Monte, DA; McCormack, A; Richfield, EK; Tank, AW; Thiruchelvam, M | 1 |
Lithgow, GJ; Olsen, A; Sampayo, JN | 1 |
Michaud, S; Morrow, G; Samson, M; Tanguay, RM | 1 |
Gems, D; Keaney, M; Matthijssens, F; Sharpe, M; Vanfleteren, J | 1 |
Allikian, MJ; Bhole, D; Tower, J | 1 |
Holzenberger, M | 1 |
Helfand, SL; Mutcherson, R; Zheng, J | 1 |
Cheng, CM; Li, X; Li, Z; Sun, JL; Wu, YL; Yin, J | 1 |
Ayusawa, D; Endoh, M; Fujii, M; Hossain, MN; Miki, K; Tanaka, N | 1 |
Magwere, T; Murphy, MP; Partridge, L; Riyahi, K; Smith, RA; West, M | 1 |
Cicchetti, F; Gross, RE; Saint-Pierre, M; Sik, A; Tremblay, ME | 1 |
Bonini, NM; Ischiropoulos, H; Meulener, MC; Thompson, L; Thomson, L; Xu, K | 1 |
Andersen, JK; Doctrow, SR; Peng, J; Peng, L; Stevenson, FF | 1 |
Bohmann, D; Sykiotis, GP | 1 |
Carr, CE; Klimczak, RR; Ruvkun, G; Samuelson, AV; Thompson, DB | 1 |
Allhorn, M; Bastiani, MJ; Do Carmo, S; Ganfornina, MD; González, C; Lora, JM; Rassart, E; Sanchez, D; Torres-Schumann, S; Vogel, M | 1 |
Benzer, S; Muffat, J; Walker, DW | 1 |
Halliwell, B | 1 |
Leung, TS; Naqvi, NZ; Naqvi, SM | 1 |
Arking, R; Dudas, SP | 1 |
He, P; Yasumoto, K | 1 |
Hartman, PS; Ishi, N; Suzuki, K; Suzuki, N | 1 |
Corasaniti, MT; Nisticò, G | 1 |
Vanfleteren, JR | 1 |
Honda, S; Ishii, N; Yamamoto, K | 1 |
Nakanishi, Y; Yasumoto, K | 1 |
Kim, YG; Yang, MK | 1 |
Kim, JS; Kim, YG; Na, CS; Pak, SC | 1 |
Ishii, N | 1 |
Fariello, RG; Gerlach, M; Riederer, P; Sulzer, D; Tampellini, D; Zecca, L | 1 |
Bonilla, E; Díaz, S; Medina-Leendertz, S | 1 |
Le Couteur, DG; McLean, AJ; Yang, MC | 1 |
Ayers, L; Kasuyama, RS; Tierney, DF | 1 |
Bus, JS; Gibson, JE | 1 |
Hayashi, S; Seto, NO; Tener, GM | 1 |
Benzi, G; Marzatico, F; Pastoris, O; Villa, RF | 1 |
Ishimoto, K; Kanoh, T; Niwa, Y | 1 |
Milić, B; Petrović, VM; Spasić, M | 1 |
1 review(s) available for paraquat and Aging
Article | Year |
---|---|
Substantia nigra neuromelanin: structure, synthesis, and molecular behaviour.
Topics: Aging; Animals; Cell Death; Chelating Agents; Cholesterol; Humans; Iron; Lipid Metabolism; Locus Coeruleus; Melanins; Paraquat; Parkinson Disease; Pesticides; Substantia Nigra; Toxins, Biological | 2001 |
75 other study(ies) available for paraquat and Aging
Article | Year |
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Protection against oxidative stress and anti-aging effect in Drosophila of royal jelly-collagen peptide.
Topics: Aging; Amino Acids; Animals; Body Weight; Collagen; Drosophila; Fatty Acids; Feeding Behavior; Hydrogen Peroxide; Longevity; Molecular Weight; Oxidative Stress; Paraquat | 2020 |
Carnitine promotes recovery from oxidative stress and extends lifespan in
Topics: Aging; Amyloid beta-Peptides; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Carnitine; DNA-Binding Proteins; Forkhead Transcription Factors; Humans; Hydrogen Peroxide; Longevity; Naphthoquinones; Organic Cation Transport Proteins; Oxidative Stress; Paraquat; Reactive Oxygen Species; Receptor, Insulin; Receptors, Notch; Stress, Physiological; Transcription Factors | 2020 |
Dietary thiols accelerate aging of C. elegans.
Topics: Acetylcysteine; Aging; Animals; Animals, Genetically Modified; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Dietary Supplements; DNA-Binding Proteins; Escherichia coli; Female; Fibroblasts; Gene Expression Regulation; Glutathione; Humans; Male; Paraquat; Reactive Oxygen Species; Sulfhydryl Compounds; Transcription Factors; Unfolded Protein Response | 2021 |
A conserved NAD
Topics: Adaptor Proteins, Signal Transducing; Aging; Animals; Conserved Sequence; DNA Damage; DNA Repair; Fibroblasts; HEK293 Cells; Humans; Mice; Models, Molecular; NAD; Neoplasms; Paraquat; Poly (ADP-Ribose) Polymerase-1; Protein Interaction Domains and Motifs; Radiation Tolerance; RNA, Small Interfering; Sequence Homology, Nucleic Acid | 2017 |
Molecular mechanisms of anti-oxidant and anti-aging effects induced by convallatoxin in Caenorhabditis elegans.
Topics: Aging; Animals; Antioxidants; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Drug Evaluation, Preclinical; Forkhead Transcription Factors; Oxidative Stress; Paraquat; Protein Transport; Reactive Oxygen Species; Strophanthins | 2017 |
The anti-oxidation and anti-aging effects of Ganoderma lucidum in Caenorhabditis elegans.
Topics: Aging; Animals; Antioxidants; Caenorhabditis elegans; Chromium; Gene Expression Profiling; Gene Expression Regulation; Longevity; Oxidation-Reduction; Oxidative Stress; Paraquat; Plant Extracts; Reishi; Signal Transduction | 2019 |
Mutational signatures of redox stress in yeast single-strand DNA and of aging in human mitochondrial DNA share a common feature.
Topics: Aging; Base Sequence; DNA Damage; DNA-Directed DNA Polymerase; DNA, Mitochondrial; DNA, Single-Stranded; Humans; Hydrogen Peroxide; Mutagenesis; Mutation; Mutation Rate; Neoplasms; Oxidation-Reduction; Paraquat; Saccharomyces cerevisiae; Stress, Physiological | 2019 |
Paraquat as an Environmental Risk Factor in Parkinson's Disease Accelerates Age-Related Degeneration Via Rapid Influx of Extracellular Zn
Topics: Aging; Animals; Dopaminergic Neurons; Exocytosis; Extracellular Space; Glutamic Acid; Male; Paraquat; Parkinson Disease; Presynaptic Terminals; Rats, Wistar; Reactive Oxygen Species; Receptors, AMPA; Risk Factors; Substantia Nigra; Zinc | 2019 |
Forkhead box O3 protects the heart against paraquat-induced aging-associated phenotypes by upregulating the expression of antioxidant enzymes.
Topics: Aging; Animals; Antioxidants; Catalase; Forkhead Box Protein O3; Heart; Mice; Mice, Knockout; Paraquat; Phenotype; Protective Agents; Superoxide Dismutase; Up-Regulation | 2019 |
Ligand binding-dependent functions of the lipocalin NLaz: an in vivo study in Drosophila.
Topics: Aging; Alkenes; Amino Acid Sequence; Animals; Animals, Genetically Modified; Carrier Proteins; Cell Line; Cell Survival; Drosophila melanogaster; Drosophila Proteins; Ergosterol; Herbicides; Hydrogen Peroxide; Ligands; Lipocalins; Membrane Glycoproteins; Models, Molecular; Molecular Sequence Data; Oxidants; Paraquat; Point Mutation; Protein Binding; Protein Structure, Tertiary; Reverse Transcriptase Polymerase Chain Reaction; Transcriptome; Tretinoin | 2014 |
Mutation in Drosophila methuselah resists paraquat induced Parkinson-like phenotypes.
Topics: Aging; Animals; Apoptosis; Caspase 3; Dopamine; Dopaminergic Neurons; Drosophila; Drosophila Proteins; Forkhead Transcription Factors; Herbicide Resistance; Herbicides; Male; MAP Kinase Kinase 4; Motor Activity; Mutation; Nerve Degeneration; Neuropeptides; Oxidative Stress; Paraquat; Parkinson Disease, Secondary; Phenotype; Receptors, G-Protein-Coupled | 2014 |
Feedback regulation via AMPK and HIF-1 mediates ROS-dependent longevity in Caenorhabditis elegans.
Topics: Aging; AMP-Activated Protein Kinases; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cell Respiration; Feedback, Physiological; Homeostasis; Iron; Longevity; Mitochondria; Mutation; Paraquat; Phosphorylation; Reactive Oxygen Species; Transcription Factors | 2014 |
DAF-16/FOXO and EGL-27/GATA promote developmental growth in response to persistent somatic DNA damage.
Topics: Aging; Animals; Animals, Genetically Modified; Caenorhabditis elegans; Caenorhabditis elegans Proteins; DNA Damage; DNA Repair; DNA-Binding Proteins; Forkhead Transcription Factors; Gene Expression Regulation, Developmental; Herbicides; Paraquat; Signal Transduction; Transcription Factors | 2014 |
Dynamic differences in oxidative stress and the regulation of metabolism with age in visceral versus subcutaneous adipose.
Topics: Adipocytes; Adipogenesis; Aging; Aldehydes; Animals; Cell Respiration; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Intra-Abdominal Fat; Lipolysis; Male; MAP Kinase Kinase 4; Mice; Mice, Inbred C57BL; Mitochondria; Oxidative Stress; Paraquat; Peroxides; Primary Cell Culture; Signal Transduction; Subcutaneous Fat | 2015 |
Bioactive Peptides from Angelica sinensis Protein Hydrolyzate Delay Senescence in Caenorhabditis elegans through Antioxidant Activities.
Topics: Aging; Amino Acid Sequence; Angelica sinensis; Animals; Antioxidants; Caenorhabditis elegans; Cattle; Chromatography, Liquid; Malondialdehyde; Molecular Sequence Data; Oxidation-Reduction; Oxidative Stress; Paraquat; Peptides; Pigments, Biological; Protein Hydrolysates; Reactive Oxygen Species; Tandem Mass Spectrometry | 2016 |
Antioxidants reveal an inverted U-shaped dose-response relationship between reactive oxygen species levels and the rate of aging in Caenorhabditis elegans.
Topics: Acetylcysteine; Aging; Animals; Antioxidants; Ascorbic Acid; Caenorhabditis elegans; Longevity; Mitochondria; Models, Biological; Mutation; Oxidative Stress; Paraquat; Reactive Oxygen Species; Resveratrol; Stilbenes; Superoxide Dismutase | 2017 |
Does age matter? Comparison of neurobehavioral effects of paraquat exposure on postnatal and adult C57BL/6 mice.
Topics: Aging; Animals; Behavior, Animal; Body Weight; Dose-Response Relationship, Drug; Environmental Pollutants; Maze Learning; Mice, Inbred C57BL; Paraquat; Reaction Time; Spatial Learning; Spatial Memory | 2016 |
Effects of decreased dopamine transporter levels on nigrostriatal neurons and paraquat/maneb toxicity in mice.
Topics: Aging; Animals; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Genetic Variation; Male; Maneb; Mice, Knockout; Mice, Mutant Strains; Paraquat; Parkinson Disease; Pars Compacta; Risk | 2017 |
The decay of Redox-stress Response Capacity is a substantive characteristic of aging: Revising the redox theory of aging.
Topics: Aging; AMP-Activated Protein Kinase Kinases; Animals; Caenorhabditis elegans; Catalase; Cellular Senescence; Child, Preschool; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Gene Expression Regulation; Glutathione Peroxidase; Glutathione S-Transferase pi; Heme Oxygenase-1; Humans; Isoenzymes; Male; NF-E2-Related Factor 2; Oxidation-Reduction; Oxidative Stress; Paraquat; Primary Cell Culture; Protein Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Superoxide Dismutase | 2017 |
Growth arrest and DNA damage protein 45b (Gadd45b) protects retinal ganglion cells from injuries.
Topics: Aging; Animals; Antigens, Differentiation; Cell Death; Cells, Cultured; Glutamic Acid; Intraocular Pressure; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidative Stress; Paraquat; Rats; Rats, Wistar; Retina; Retinal Ganglion Cells; RNA, Small Interfering; Tumor Necrosis Factor-alpha | 2009 |
SOD isoforms play no role in lifespan in ad lib or dietary restricted conditions, but mutational inactivation of SOD-1 reduces life extension by cold.
Topics: Aging; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Caloric Restriction; Cellular Senescence; Cold Temperature; Gene Silencing; Isoenzymes; Longevity; Mutation; Oxidative Stress; Paraquat; Stress, Physiological; Superoxide Dismutase; Superoxide Dismutase-1 | 2009 |
Long-lived ames dwarf mice are resistant to chemical stressors.
Topics: Aging; Alanine Transaminase; Animals; Diquat; Dwarfism; Exercise Test; Female; Lipid Peroxidation; Liver; Longevity; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Paraquat | 2009 |
LRRK2 modulates vulnerability to mitochondrial dysfunction in Caenorhabditis elegans.
Topics: Aging; Animals; Animals, Genetically Modified; Caenorhabditis elegans; Dopamine; Gene Knockdown Techniques; Herbicides; Insecticides; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mitochondria; Mortality; Mutation; Neurons; Paraquat; Protein Serine-Threonine Kinases; RNA, Messenger; Rotenone | 2009 |
Transgenerational memory effect of ageing in Drosophila.
Topics: Aging; Animals; Biological Evolution; Drosophila; Insecticide Resistance; Insecticides; Memory; Oxidative Stress; Paraquat; Sex Characteristics | 2010 |
The role of p38b MAPK in age-related modulation of intestinal stem cell proliferation and differentiation in Drosophila.
Topics: Adult Stem Cells; Aging; Animals; Animals, Genetically Modified; Cell Differentiation; Cell Proliferation; Drosophila melanogaster; Drosophila Proteins; Enterocytes; Enteroendocrine Cells; Gene Expression; Intestinal Mucosa; Intestines; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Mitogen-Activated Protein Kinase 11; Nerve Tissue Proteins; Nuclear Proteins; Oxidative Stress; Paraquat; Receptor Protein-Tyrosine Kinases; Repressor Proteins; Signal Transduction; Stem Cells; Transcription Factors | 2009 |
A deuterohemin peptide extends lifespan and increases stress resistance in Caenorhabditis elegans.
Topics: Aging; Animals; Animals, Genetically Modified; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cytochromes b; Drug Evaluation, Preclinical; Forkhead Transcription Factors; Gene Expression Profiling; Gene Knockdown Techniques; Genes, Helminth; Hemin; Hot Temperature; Longevity; Oligopeptides; Oxidative Stress; Paraquat; Sirtuins; Stress, Physiological; Succinate Dehydrogenase; Transcription Factors | 2010 |
DDS, 4,4'-diaminodiphenylsulfone, extends organismic lifespan.
Topics: Aging; Animals; Antioxidants; Caenorhabditis elegans; Cell Line; Dapsone; Longevity; Mitochondrial Proteins; Muscle, Skeletal; Oxygen Consumption; Paraquat; Pyruvate Kinase; Reactive Oxygen Species | 2010 |
Synergistic effects of environmental risk factors and gene mutations in Parkinson's disease accelerate age-related neurodegeneration.
Topics: Aging; alpha-Synuclein; Animals; Cell Line; Cells, Cultured; Disease Progression; Environmental Exposure; Humans; Iron; Mice; Mice, Transgenic; Mutation; Nerve Degeneration; Paraquat; Parkinson Disease; Rats; Risk Factors | 2010 |
mIGF-1/JNK1/SirT1 signaling confers protection against oxidative stress in the heart.
Topics: Aging; Animals; Animals, Newborn; Heart Failure; Insulin-Like Growth Factor I; Mice; Mice, Transgenic; Mitogen-Activated Protein Kinase 8; Myocardium; Myocytes, Cardiac; Oxidative Stress; Paraquat; Primary Cell Culture; Rats; RNA, Small Interfering; Signal Transduction; Sirtuin 1; Transfection | 2012 |
Reactive oxygen species are not involved in the onset of age-related memory impairment in Drosophila.
Topics: Aging; Animals; Association Learning; Catalase; Disease Models, Animal; Drosophila; Drosophila Proteins; Heat-Shock Proteins; Herbicides; Hydrogen Peroxide; Memory Disorders; Mushroom Bodies; Oxidants; Oxidative Stress; Paraquat; Reactive Oxygen Species | 2012 |
[Effect of antioxidant responsive element inducing phenol on D. melanogaster life span].
Topics: Adaptation, Physiological; Aging; Animals; Antioxidants; Drosophila melanogaster; Female; Herbicides; Hydrogen Peroxide; Longevity; Male; Models, Animal; Oxidants; Oxidative Stress; Paraquat; Phenols; Protective Agents; Sex Factors; Thiosulfonic Acids | 2011 |
Unincorporated iron pool is linked to oxidative stress and iron levels in Caenorhabditis elegans.
Topics: Aging; Animals; Caenorhabditis elegans; Electron Spin Resonance Spectroscopy; Heat-Shock Response; Hydrogen Peroxide; Iron; Oxidants; Oxidative Stress; Paraquat; Reactive Oxygen Species | 2012 |
An engineering approach to extending lifespan in C. elegans.
Topics: Aging; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Animals; Animals, Genetically Modified; Caenorhabditis elegans; Cell Survival; Gene Expression; Humans; Longevity; Oxidative Stress; Paraquat; Zebrafish; Zebrafish Proteins | 2012 |
Different age-specific demographic profiles are generated in the same normal-lived Drosophila strain by different longevity stimuli.
Topics: Aging; Animals; Antioxidants; Drosophila; Drug Resistance; Fertility; Hot Temperature; Longevity; Paraquat; Phenotype | 2002 |
Developmental exposure to the pesticides paraquat and maneb and the Parkinson's disease phenotype.
Topics: Aging; Animals; Animals, Newborn; Body Weight; Cell Count; Chromatography, High Pressure Liquid; Dopamine; Fungicides, Industrial; Herbicides; Homovanillic Acid; Immunohistochemistry; Male; Maneb; Mice; Mice, Inbred C57BL; Motor Activity; Paraquat; Parkinson Disease; Phenotype; Serotonin; Tyrosine 3-Monooxygenase | 2002 |
Age-related impairment of the transcriptional responses to oxidative stress in the mouse heart.
Topics: Aging; Animals; Antioxidants; Dual-Specificity Phosphatases; GADD45 Proteins; Gene Expression Profiling; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Genes, Immediate-Early; Genes, jun; Heart; Injections, Intraperitoneal; Intracellular Signaling Peptides and Proteins; Lipid Peroxidation; Male; Mice; Mice, Inbred C57BL; Oligonucleotide Array Sequence Analysis; Oxidative Stress; Paraquat; Phosphoprotein Phosphatases; Protein Biosynthesis; Protein Tyrosine Phosphatases; Proteins; Transcription, Genetic | 2003 |
Variable effects of vitamin E on Drosophila longevity.
Topics: Aging; Animals; Antioxidants; Circadian Rhythm; Drosophila melanogaster; Herbicides; Humans; Life Expectancy; Male; Paraquat; Vitamin E | 2003 |
Age-related irreversible progressive nigrostriatal dopaminergic neurotoxicity in the paraquat and maneb model of the Parkinson's disease phenotype.
Topics: Aging; Animals; Cell Count; Corpus Striatum; Disease Susceptibility; Dopamine; Drug Combinations; Glutamate Decarboxylase; Male; Maneb; Mice; Mice, Inbred C57BL; Motor Activity; Neurons; Neurotoxins; Paraquat; Parkinson Disease, Secondary; Phenotype; Serotonin; Substantia Nigra; Tyrosine 3-Monooxygenase | 2003 |
Oxidative stress in Caenorhabditis elegans: protective effects of superoxide dismutase/catalase mimetics.
Topics: Aging; Animals; Antioxidants; Caenorhabditis elegans; Catalase; Ethylenediamines; Organometallic Compounds; Oxidative Stress; Paraquat; Salicylates; Superoxide Dismutase | 2003 |
Overexpression of the small mitochondrial Hsp22 extends Drosophila life span and increases resistance to oxidative stress.
Topics: Aging; Animals; Drosophila melanogaster; Drosophila Proteins; Genetic Vectors; Heat-Shock Proteins; Hot Temperature; Longevity; Male; Mitochondria; Motor Activity; Motor Neurons; Nerve Tissue Proteins; Oxidative Stress; Paraquat; Reactive Oxygen Species; Recombinant Fusion Proteins; Stress, Physiological | 2004 |
Superoxide dismutase mimetics elevate superoxide dismutase activity in vivo but do not retard aging in the nematode Caenorhabditis elegans.
Topics: Aging; Animals; Antinematodal Agents; Biomimetics; Caenorhabditis elegans; Cyanides; Cytosol; Dose-Response Relationship, Drug; Escherichia coli; Ethylenediamines; Free Radicals; Herbicides; Manganese Compounds; Mitochondria; Naphthoquinones; Organometallic Compounds; Oxidants; Oxygen Consumption; Paraquat; Reactive Oxygen Species; Salicylates; Superoxide Dismutase; Superoxides; Time Factors | 2004 |
Impairment of the transcriptional responses to oxidative stress in the heart of aged C57BL/6 mice.
Topics: Aging; Animals; DNA Damage; GADD45 Proteins; Inflammation; Intracellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL; Myocardium; Oligonucleotide Array Sequence Analysis; Oxidative Stress; Paraquat; Protein Isoforms; Proteins; RNA, Messenger; Time Factors; Transcription, Genetic | 2004 |
Doxycycline-regulated over-expression of hsp22 has negative effects on stress resistance and life span in adult Drosophila melanogaster.
Topics: Aging; Animals; Coumarins; Disease Susceptibility; Doxycycline; Drosophila melanogaster; Drosophila Proteins; Drug Resistance; Gene Expression Regulation; Genes, Reporter; Heat Stress Disorders; Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Longevity; Male; Oxidative Stress; Paraquat; Transcription, Genetic | 2004 |
The role of insulin-like signalling in the regulation of ageing.
Topics: Aging; Animals; Down-Regulation; Female; Heterozygote; Insulin-Like Growth Factor I; Longevity; Male; Mice; Oxidative Stress; Paraquat; Receptor, IGF Type 1; Signal Transduction | 2004 |
Calorie restriction delays lipid oxidative damage in Drosophila melanogaster.
Topics: Aging; Aldehydes; Animals; Brain; Caloric Restriction; Drosophila melanogaster; Enzyme-Linked Immunosorbent Assay; Fat Body; Female; Lipid Peroxidation; Longevity; Male; Mitochondrial Proteins; Muscles; Oxidative Stress; Paraquat | 2005 |
Paraquat induces selective dopaminergic nigrostriatal degeneration in aging C57BL/6 mice.
Topics: Aging; Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Male; Mice; Mice, Inbred C57BL; Motor Activity; Paraquat; Parkinson Disease, Secondary; Substantia Nigra; Tyrosine 3-Monooxygenase | 2005 |
Uncoupling of longevity and paraquat resistance in mutants of the nematode Caenorhabditis elegans.
Topics: Aging; Animals; Caenorhabditis elegans; Drug Resistance; Longevity; Models, Animal; Oxidative Stress; Paraquat | 2005 |
The effects of exogenous antioxidants on lifespan and oxidative stress resistance in Drosophila melanogaster.
Topics: Aging; Animals; Animals, Genetically Modified; Antioxidants; Dose-Response Relationship, Drug; Drosophila melanogaster; Female; Free Radicals; Genes, Insect; Homozygote; Longevity; Male; Models, Statistical; Onium Compounds; Organophosphorus Compounds; Oxidative Stress; Paraquat; RNA Interference; Sex Factors; Superoxide Dismutase; Temperature; Time Factors; Trityl Compounds; Ubiquinone | 2006 |
Temporal effects of paraquat/maneb on microglial activation and dopamine neuronal loss in older rats.
Topics: Aging; Animals; Cell Death; Dopamine; Drug Administration Schedule; Drug Combinations; Male; Maneb; Microglia; Nerve Degeneration; Neurons; Paraquat; Rats; Rats, Sprague-Dawley; Time Factors | 2006 |
Mutational analysis of DJ-1 in Drosophila implicates functional inactivation by oxidative damage and aging.
Topics: Aging; Animals; Animals, Genetically Modified; Cysteine; DNA Mutational Analysis; Drosophila melanogaster; Drosophila Proteins; Herbicides; Humans; Mice; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Oxidative Stress; Paraquat; Parkinson Disease; Protein Deglycase DJ-1 | 2006 |
Iron and paraquat as synergistic environmental risk factors in sporadic Parkinson's disease accelerate age-related neurodegeneration.
Topics: Aging; Animals; Cell Line; Cells, Cultured; Drug Synergism; Environmental Exposure; Herbicides; Iron; Male; Mice; Mice, Inbred C57BL; Nerve Degeneration; Neurons; Neuroprotective Agents; Organometallic Compounds; Paraquat; Parkinson Disease; Rats; Salicylates; Substantia Nigra; Superoxide Dismutase | 2007 |
Keap1/Nrf2 signaling regulates oxidative stress tolerance and lifespan in Drosophila.
Topics: Aging; Animals; Cell Survival; Conserved Sequence; Drosophila; Drosophila Proteins; Female; Gene Expression Regulation; Intracellular Signaling Peptides and Proteins; Kelch-Like ECH-Associated Protein 1; Life Expectancy; Male; Mutation; NF-E2-Related Factor 2; Oxidative Stress; Paraquat; Signal Transduction; Transcriptional Activation | 2008 |
Identification of Caenorhabditis elegans genes regulating longevity using enhanced RNAi-sensitive strains.
Topics: Aging; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Drug Resistance; Genes, Helminth; Heat-Shock Response; Longevity; Mutation; Paraquat; Pigmentation; Receptor, Insulin; RNA Interference | 2007 |
Apolipoprotein D is involved in the mechanisms regulating protection from oxidative stress.
Topics: Aging; Animals; Apolipoproteins D; Behavior, Animal; Brain; Glycoproteins; Humans; Learning; Lipid Peroxidation; Lipocalins; Membrane Transport Proteins; Mice; Mice, Transgenic; Motor Activity; Nervous System; Oxidative Stress; Paraquat; Survival Analysis; Transgenes; Up-Regulation | 2008 |
Human ApoD, an apolipoprotein up-regulated in neurodegenerative diseases, extends lifespan and increases stress resistance in Drosophila.
Topics: Aging; Amyloid beta-Peptides; Animals; Animals, Genetically Modified; Apolipoproteins D; Carrier Proteins; Drosophila melanogaster; Drosophila Proteins; Glycoproteins; Humans; Lipid Peroxides; Longevity; Membrane Glycoproteins; Membrane Transport Proteins; Neurodegenerative Diseases; Paraquat; Peptide Fragments; RNA, Messenger; Up-Regulation | 2008 |
Oxygen is poisonous: the nature and medical importance of oxygen radicals.
Topics: Adult; Aging; Animals; Bacteria, Aerobic; Bacteria, Anaerobic; Free Radicals; Humans; Hydrogen Peroxide; Infant, Newborn; Oxidation-Reduction; Oxygen; Paraquat; Phagocytosis; Structure-Activity Relationship; Superoxides | 1984 |
Paraquat toxicity to Louisiana crayfish (Procambarus clarkii).
Topics: Aging; Animals; Astacoidea; Hydrogen-Ion Concentration; Lethal Dose 50; Louisiana; Oxygen; Paraquat; Temperature; Time Factors | 1980 |
A coordinate upregulation of antioxidant gene activities is associated with the delayed onset of senescence in a long-lived strain of Drosophila.
Topics: Aging; Animals; Antioxidants; Catalase; Drosophila melanogaster; Drug Resistance; Gene Expression; Glutathione Transferase; Longevity; Paraquat; Phenotype; RNA, Messenger; Superoxide Dismutase; Up-Regulation; Xanthine Dehydrogenase | 1995 |
Dietary butylated hydroxytoluene counteracts with paraquat to reduce the rate of hepatic DNA single strand breaks in senescence-accelerated mice.
Topics: Aging; Animals; Butylated Hydroxytoluene; Diet; DNA Damage; DNA, Single-Stranded; Drug Interactions; Liver; Male; Mice; Mice, Inbred Strains; Oxidative Stress; Paraquat | 1994 |
The radiation-sensitive mutant rad-8 of Caenorhabditis elegans is hypersensitive to the effects of oxygen on aging and development.
Topics: Aging; Animals; Caenorhabditis elegans; Fertility; Longevity; Mutation; Oxygen; Paraquat; Radiation Tolerance; Survival Rate | 1993 |
Determination of paraquat in rat brain by high-performance liquid chromatography.
Topics: Aging; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Male; Paraquat; Rats; Rats, Wistar; Spectrophotometry, Ultraviolet | 1993 |
Oxidative stress and ageing in Caenorhabditis elegans.
Topics: Aging; Animals; Caenorhabditis elegans; Catalase; Drug Resistance; Glutathione Peroxidase; Microsomes; Oxidation-Reduction; Paraquat; Superoxide Dismutase; Superoxides | 1993 |
Properties of an oxygen-sensitive mutant mev-3 of the nematode Caenorhabditis elegans.
Topics: Aging; Animals; Body Constitution; Caenorhabditis elegans; Fertility; Life Expectancy; Mutation; Oxygen; Paraquat; Reactive Oxygen Species | 1996 |
Induction after administering paraquat of heme oxygenase-1 and heat shock protein 70 in the liver of senescence-accelerated mice.
Topics: Aging; Animals; Enzyme Induction; Heme Oxygenase (Decyclizing); Herbicides; HSP70 Heat-Shock Proteins; In Vitro Techniques; Liver; Male; Mice; Mice, Inbred Strains; Oxidation-Reduction; Paraquat | 1997 |
Protective role of germanium-132 against paraquat-induced oxidative stress in the livers of senescence-accelerated mice.
Topics: Aging; Animals; Antioxidants; Catalase; DNA Damage; Free Radicals; Germanium; Herbicides; Lipid Peroxidation; Liver; Malondialdehyde; Mice; Mice, Inbred Strains; Microscopy, Electron; Organometallic Compounds; Oxidative Stress; Paraquat; Propionates; Superoxide Dismutase | 1999 |
Effects of yukmi, an herbal formula, on the liver of senescence accelerated mice (SAM) exposed to oxidative stress.
Topics: Aging; Animals; Antioxidants; Catalase; Drugs, Chinese Herbal; Liver; Malondialdehyde; Mice; Mitochondria, Liver; Oxidants; Oxidative Stress; Paraquat; Plant Extracts; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2000 |
Oxidative stress and aging in Caenorhabditis elegans.
Topics: Aging; Animals; Caenorhabditis elegans; Longevity; Mutation; Oxidative Stress; Oxygen; Paraquat | 2000 |
Extension of life span and stress resistance of Drosophila melanogaster by long-term supplementation with melatonin.
Topics: Aging; Animals; Antioxidants; Drosophila melanogaster; Drug Resistance; Free Radical Scavengers; Free Radicals; Longevity; Male; Melatonin; Models, Biological; Oxidative Stress; Paraquat; Stress, Physiological; Temperature | 2002 |
Age-related alteration in hepatic disposition of the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and pesticides.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Aging; Animals; DDT; Dopamine Agents; Liver; Malathion; Male; Paraquat; Perfusion; Pesticides; Rats; Rats, Inbred F344 | 2002 |
Altered sensitivity to oxygen toxicity.
Topics: Aging; Animals; Body Weight; Drug Tolerance; Glucose; Glucosephosphate Dehydrogenase; In Vitro Techniques; Lung; Male; Mice; Oxygen; Oxygen Consumption; Paraquat; Rats; Species Specificity; Thiourea | 1977 |
Postnatal toxicity of chronically administered paraquat in mice and interactions with oxygen and bromobenzene.
Topics: Aging; Animals; Animals, Newborn; Bromobenzenes; Drug Interactions; Drug Stability; Female; Gestational Age; Growth; Lung; Maternal-Fetal Exchange; Mice; Oxygen; Paraquat; Pregnancy; Pregnancy, Animal | 1975 |
Overexpression of Cu-Zn superoxide dismutase in Drosophila does not affect life-span.
Topics: Aging; Animals; Animals, Genetically Modified; Blotting, Northern; Blotting, Southern; Drosophila melanogaster; Free Radicals; Gene Expression; Paraquat; Superoxide Dismutase; Transformation, Genetic | 1990 |
Influence of oxidative stress on the age-linked alterations of the cerebral glutathione system.
Topics: Administration, Oral; Aging; Amitrole; Animals; Ditiocarb; Frontal Lobe; Glutathione; Hydrogen Peroxide; Male; Oxidation-Reduction; Oxygen; Paraquat; Phosphatidylcholines; Rats; Rats, Inbred Strains; Superoxides | 1990 |
Induction of superoxide dismutase in leukocytes by paraquat: correlation with age and possible predictor of longevity.
Topics: Adult; Aged; Aged, 80 and over; Aging; Disease Susceptibility; Enzyme Induction; Female; Humans; Leukocytes; Longevity; Male; Middle Aged; Paraquat; Superoxide Dismutase | 1990 |
Age-dependent resistance to the toxic effects of paraquat in relation to superoxide dismutase activity in rat lung.
Topics: Aging; Animals; Liver; Lung; Paraquat; Rats; Superoxide Dismutase | 1986 |