Page last updated: 2024-11-02

papaverine and Vertigo

papaverine has been researched along with Vertigo in 10 studies

Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.

Vertigo: An illusion of movement, either of the external world revolving around the individual or of the individual revolving in space. Vertigo may be associated with disorders of the inner ear (EAR, INNER); VESTIBULAR NERVE; BRAINSTEM; or CEREBRAL CORTEX. Lesions in the TEMPORAL LOBE and PARIETAL LOBE may be associated with FOCAL SEIZURES that may feature vertigo as an ictal manifestation. (From Adams et al., Principles of Neurology, 6th ed, pp300-1)

Research Excerpts

Excerpt	Relevance	Reference
"This is the first double-blind study in outpatients to evaluate the effectiveness of dihydrogenated ergot alkaloids (DEA) (Hydergine) versus papaverine in the treatment of selected symptoms associated with mental aging."	5.04	Mental decline in the elderly: pharmacotherapy (ergot alkaloids versus papaverine). ( Rosen, HJ, 1975)

Research

Studies (10)

Timeframe	Studies, this research(%)	All Research%
pre-1990	10 (100.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
HOHMANN, H	2
STOLL, HG	1
Byl, FM	1
Rosen, HJ	1
Feine-Haake, G	1
Neiss, A	1
Weinert, W	1
Agnoli, A	2
Piccinelli, A	1
Neri, G	1
Turner, JS	1
Saunders, AZ	1
Per-Lee, JH	1
Straube, G	1

Clinical Trials (2)

Trial Overview

Trial	Phase	Enrollment	Study Type	Start Date	Status
Predictive Factors for Recovery in Idiopathic Sensory Neural Hearing Loss[NCT05112354]	Phase 2	40 participants (Actual)	Interventional	2019-12-01	Completed
Cochlear Implantation in Single Sided Deafness and Asymmetrical Hearing Loss: a Cost/Utility Study.[NCT02204618]		160 participants (Actual)	Interventional	2014-10-31	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for papaverine and Vertigo

Article	Year
Sudden hearing loss: eight years' experience and suggested prognostic table. The Laryngoscope, 1984, Volume: 94, Issue:5 Pt 1 Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Age Factors; Aged; Blood Coagulation Disorders; Chil	1984
Sudden hearing loss: eight years' experience and suggested prognostic table. The Laryngoscope, 1984, Volume: 94, Issue:5 Pt 1 Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Age Factors; Aged; Blood Coagulation Disorders; Chil	1984
Sudden hearing loss: eight years' experience and suggested prognostic table. The Laryngoscope, 1984, Volume: 94, Issue:5 Pt 1 Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Age Factors; Aged; Blood Coagulation Disorders; Chil	1984
Sudden hearing loss: eight years' experience and suggested prognostic table. The Laryngoscope, 1984, Volume: 94, Issue:5 Pt 1 Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Age Factors; Aged; Blood Coagulation Disorders; Chil	1984

Trials

3 trials available for papaverine and Vertigo

Article	Year
Mental decline in the elderly: pharmacotherapy (ergot alkaloids versus papaverine). Journal of the American Geriatrics Society, 1975, Volume: 23, Issue:4 Topics: Aged; Aging; Clinical Trials as Topic; Confusion; Dementia; Depression; Dihydroergotoxine; Ergoloid	1975
[The treatment of cerebrovascular insufficiency. Their evaluation in a double-blind study]. MMW, Munchener medizinische Wochenschrift, 1975, Jun-27, Volume: 117, Issue:26 Topics: Aged; Aging; Cerebrovascular Disorders; Clinical Trials as Topic; Confusion; Drug Combinations; Drug	1975
[Long-term medical treatment of acute cerebrovascular disease sequelae (comparison papaverine-piribedil]. Minerva medica, 1974, Nov-10, Volume: 65, Issue:80 Topics: Cerebrovascular Circulation; Cerebrovascular Disorders; Clinical Trials as Topic; Dioxoles; Drug Eva	1974

Other Studies

6 other studies available for papaverine and Vertigo

Article	Year
[Contribution to the management of labyrinthine and vasomotor vertigo]. Medizinische Klinik, 1956, Mar-02, Volume: 51, Issue:9 Topics: Humans; Meniere Disease; Papaverine; Quinine; Vertigo	1956
[Further experiences with the treatment of labyrinthine & vasomotor dizziness; contribution to the problem of placebos]. Medizinische Klinik, 1958, Aug-29, Volume: 53, Issue:35 Topics: Dizziness; Humans; Meniere Disease; Papaverine; Quinine; Vertigo	1958
[On the medicinal treatment of dizziness]. Zeitschrift fur arztliche Fortbildung, 1960, Apr-01, Volume: 54 Topics: Dizziness; Humans; Meniere Disease; Papaverine; Quinine; Vertigo	1960
[Problems in the long-term medical treatment of sequelae of acute cerebrovascular diseases. Double-blind studies]. Minerva medica, 1976, May-26, Volume: 67, Issue:26 Topics: Cerebrovascular Disorders; Cognition Disorders; Emotions; Headache; Humans; Mental Processes; Motor	1976
A 10-year profile of Meniere's disease and endolymphatic shunt surgery. The Laryngoscope, 1973, Volume: 83, Issue:11 Topics: Adult; Aged; Ear, Inner; Female; Hearing; Histamine; Humans; Labyrinthine Fluids; Male; Meniere Dise	1973
[On the evaluation and treatment of vertigo in the neurological practice]. Die Medizinische Welt, 1969, Feb-01, Volume: 5 Topics: Humans; Papaverine; Quinine; Vertigo	1969