papaverine has been researched along with Varicocele in 1 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Varicocele: A condition characterized by the dilated tortuous veins of the SPERMATIC CORD with a marked left-sided predominance. Adverse effect on male fertility occurs when varicocele leads to an increased scrotal (and testicular) temperature and reduced testicular volume.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess the levels of adrenomedullin (a vasodilatory peptide) in penile blood before and after injection with papaverine in impotent men, and in the internal spermatic vein in infertile patients with varicocele, comparing the results with levels in the brachial vein in the same patients." | 9.09 | The role of adrenomedullin in varicocele and impotence. ( Balbay, MD; Davarci, M; Ozbek, E; Soylu, A; Yurekli, M, 2000) |
| "To assess the levels of adrenomedullin (a vasodilatory peptide) in penile blood before and after injection with papaverine in impotent men, and in the internal spermatic vein in infertile patients with varicocele, comparing the results with levels in the brachial vein in the same patients." | 5.09 | The role of adrenomedullin in varicocele and impotence. ( Balbay, MD; Davarci, M; Ozbek, E; Soylu, A; Yurekli, M, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ozbek, E | 1 |
| Yurekli, M | 1 |
| Soylu, A | 1 |
| Davarci, M | 1 |
| Balbay, MD | 1 |
1 trial available for papaverine and Varicocele
| Article | Year |
|---|---|
The role of adrenomedullin in varicocele and impotence.
Topics: Adrenomedullin; Adult; Biomarkers; Erectile Dysfunction; Humans; Infertility, Male; Injections; Male | 2000 |