Page last updated: 2024-11-02

papaverine and Ureteral Calculi

papaverine has been researched along with Ureteral Calculi in 8 studies

Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.

Ureteral Calculi: Stones in the URETER that are formed in the KIDNEY. They are rarely more than 5 mm in diameter for larger renal stones cannot enter ureters. They are often lodged at the ureteral narrowing and can cause excruciating renal colic.

Research Excerpts

ExcerptRelevanceReference
"Drotaverine was effective in 79% of patients and placebo in only 46% (P < 0."2.71The effect of drotaverine hydrochloride in acute colicky pain caused by renal and ureteric stones. ( Blaskó, G; Jelakovic, B; Köszegi, G; Molnár, DL; Mrklic, B; Romics, I; Timberg, G, 2003)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19905 (62.50)18.7374
1990's0 (0.00)18.2507
2000's3 (37.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yencilek, F1
Aktas, C1
Goktas, C1
Yilmaz, C1
Yilmaz, U1
Sarica, K1
Romics, I1
Molnár, DL1
Timberg, G1
Mrklic, B1
Jelakovic, B1
Köszegi, G1
Blaskó, G1
Ukhal', MI1
Melenevskiĭ, DA1
Vecsey, D1
Bick, C1
Suckow, B1
Heil, G1
Lehtonen, T1
Holm-Nielsen, P1
Fjeldborg, N1
Dorff, B1
Holmlund, D1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy of Tramadol Hcl in the Treatment of Renal Colic[NCT00310908]Phase 4100 participants (Anticipated)Interventional2006-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

4 trials available for papaverine and Ureteral Calculi

ArticleYear
Role of papaverine hydrochloride administration in patients with intractable renal colic: randomized prospective trial.
    Urology, 2008, Volume: 72, Issue:5

    Topics: Adolescent; Adult; Colic; Female; Follow-Up Studies; Humans; Male; Middle Aged; Pain Measurement; Pa

2008
The effect of drotaverine hydrochloride in acute colicky pain caused by renal and ureteric stones.
    BJU international, 2003, Volume: 92, Issue:1

    Topics: Acute Disease; Adult; Colic; Double-Blind Method; Female; Humans; Kidney Calculi; Male; Pain Measure

2003
[Using prostaglandin inhibitor dicloberl in patients with ureteral calculi].
    Likars'ka sprava, 2004, Issue:2

    Topics: Adult; Aged; Analgesics, Opioid; Diclofenac; Drug Therapy, Combination; Female; Humans; Male; Middle

2004
Passage of ureteral concretions. A clinical and experimental study on the role of different therapeutic methods and urinary tract infection on the passage of ureteral concretions.
    Annales chirurgiae et gynaecologiae Fenniae. Supplementum, 1972, Volume: 181

    Topics: Aminophylline; Animals; Anti-Infective Agents, Urinary; Cystoscopy; Diuresis; Female; Furosemide; Hu

1972

Other Studies

4 other studies available for papaverine and Ureteral Calculi

ArticleYear
Importance of No-Spa and Probon combination in the conservative treatment of ureterolithiasis patients.
    Therapia Hungarica (English edition), 1984, Volume: 32, Issue:3

    Topics: Adult; Aged; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Papaverine; Parasympathol

1984
[Indomethacin in the treatment of ureteral colic caused by calculi].
    Zeitschrift fur Urologie und Nephrologie, 1986, Volume: 79, Issue:12

    Topics: Adolescent; Adult; Aged; Aminopyrine; Analgesics; Colic; Dipyrone; Drug Therapy, Combination; Female

1986
Treatment of juxtavesical ureteral calculi with lumbar sympathetic block.
    Scandinavian journal of urology and nephrology, 1969, Volume: 3, Issue:1

    Topics: Adult; Aged; Autonomic Nerve Block; Female; Hematuria; Humans; Lumbosacral Region; Male; Papaverine;

1969
Ureteral stones. An experimental and clinical study of the mechanism of the passage and arrest of ureteral stones.
    Scandinavian journal of urology and nephrology, 1968, Volume: 1

    Topics: Adult; Aluminum; Animals; Biomechanical Phenomena; Contrast Media; Dilatation; Elastic Tissue; Elast

1968