papaverine has been researched along with Thrombopenia in 3 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This action carried over to ex vivo situation following intraduodenal dosing as demonstrated in rabbits." | 1.27 | Inhibition of platelet aggregation by a new agent, 2,2'-dithiobis-(N-2-hydroxypropyl benzamide) (KF4939). ( Nakamizo, N; Shuto, K; Yamada, K, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yamada, K | 1 |
| Shuto, K | 1 |
| Nakamizo, N | 1 |
| Miller, JA | 1 |
| Cross, DT | 1 |
| Moran, CJ | 1 |
| Dacey, RG | 1 |
| McFarland, JG | 1 |
| Diringer, MN | 1 |
| Kreiskott, H | 1 |
| Hofmann, HP | 1 |
3 other studies available for papaverine and Thrombopenia
| Article | Year |
|---|---|
Inhibition of platelet aggregation by a new agent, 2,2'-dithiobis-(N-2-hydroxypropyl benzamide) (KF4939).
Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Benzamides; Collagen; | 1983 |
Severe thrombocytopenia following intraarterial papaverine administration for treatment of vasospasm.
Topics: Aged; Antibodies; Blood Platelets; Cerebral Angiography; Humans; Infusions, Intra-Arterial; Intracra | 1995 |
[Animal experiment studies on the inhibition of platelet aggregation by verapamil in vitro and in vivo].
Topics: Adenosine Diphosphate; Animals; Aspirin; Depression, Chemical; Dipyridamole; Dogs; Fatty Acids; Huma | 1973 |