papaverine has been researched along with Stroke in 4 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
| Excerpt | Relevance | Reference |
|---|---|---|
| "This small study suggests that intra-arterial infusion of papaverine for the treatment of cerebral vasospasm after mechanical thrombectomy in acute ischemic stroke is effective and safe." | 7.81 | Intra-arterial administration of papaverine during mechanical thrombectomy for acute ischemic stroke. ( Al Shameri, RA; Baltsavias, G; Luft, A; Valavanis, A; Yella, S, 2015) |
| "Selective intraarterial infusion of papaverine is used in the treatment of symptomatic cerebral vasospasm induced by aneurysmal subarachnoid hemorrhage (SAH)." | 7.71 | Reversal of radiographically impending stroke with multiple intraarterial papaverine infusions in severe diffuse cerebral vasospasm induced by subarachnoid hemorrhage. ( Couldwell, WT; Liu, JK; Oestreich, HM; Tenner, MS, 2001) |
| "This small study suggests that intra-arterial infusion of papaverine for the treatment of cerebral vasospasm after mechanical thrombectomy in acute ischemic stroke is effective and safe." | 3.81 | Intra-arterial administration of papaverine during mechanical thrombectomy for acute ischemic stroke. ( Al Shameri, RA; Baltsavias, G; Luft, A; Valavanis, A; Yella, S, 2015) |
| "Selective intraarterial infusion of papaverine is used in the treatment of symptomatic cerebral vasospasm induced by aneurysmal subarachnoid hemorrhage (SAH)." | 3.71 | Reversal of radiographically impending stroke with multiple intraarterial papaverine infusions in severe diffuse cerebral vasospasm induced by subarachnoid hemorrhage. ( Couldwell, WT; Liu, JK; Oestreich, HM; Tenner, MS, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baltsavias, G | 1 |
| Yella, S | 1 |
| Al Shameri, RA | 1 |
| Luft, A | 1 |
| Valavanis, A | 1 |
| Lima, B | 1 |
| Nowicki, ER | 1 |
| Blackstone, EH | 1 |
| Williams, SJ | 1 |
| Roselli, EE | 1 |
| Sabik, JF | 1 |
| Lytle, BW | 1 |
| Svensson, LG | 1 |
| NUTI, A | 1 |
| SCIAGRA, A | 1 |
| Liu, JK | 1 |
| Tenner, MS | 1 |
| Oestreich, HM | 1 |
| Couldwell, WT | 1 |
4 other studies available for papaverine and Stroke
| Article | Year |
|---|---|
Intra-arterial administration of papaverine during mechanical thrombectomy for acute ischemic stroke.
Topics: Aged; Brain Ischemia; Combined Modality Therapy; Female; Fibrinolytic Agents; Humans; Infusions, Int | 2015 |
Spinal cord protective strategies during descending and thoracoabdominal aortic aneurysm repair in the modern era: the role of intrathecal papaverine.
Topics: Aged; Aortic Aneurysm, Thoracic; Blood Vessel Prosthesis Implantation; Chi-Square Distribution; Fema | 2012 |
[Research on the action of vasoactive drugs on cerebral circulation in patients suffering from apoplectic strokes. III. Action of papaverine].
Topics: Brain; Cardiovascular System; Cerebrovascular Circulation; Humans; Papaverine; Stroke | 1959 |
Reversal of radiographically impending stroke with multiple intraarterial papaverine infusions in severe diffuse cerebral vasospasm induced by subarachnoid hemorrhage.
Topics: Adult; Brain Ischemia; Female; Humans; Infusions, Intra-Arterial; Male; Papaverine; Stroke; Subarach | 2001 |