Page last updated: 2024-11-02

papaverine and Sterility, Male

papaverine has been researched along with Sterility, Male in 3 studies

Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.

Research Excerpts

ExcerptRelevanceReference
"To assess the levels of adrenomedullin (a vasodilatory peptide) in penile blood before and after injection with papaverine in impotent men, and in the internal spermatic vein in infertile patients with varicocele, comparing the results with levels in the brachial vein in the same patients."9.09The role of adrenomedullin in varicocele and impotence. ( Balbay, MD; Davarci, M; Ozbek, E; Soylu, A; Yurekli, M, 2000)
"To assess the levels of adrenomedullin (a vasodilatory peptide) in penile blood before and after injection with papaverine in impotent men, and in the internal spermatic vein in infertile patients with varicocele, comparing the results with levels in the brachial vein in the same patients."5.09The role of adrenomedullin in varicocele and impotence. ( Balbay, MD; Davarci, M; Ozbek, E; Soylu, A; Yurekli, M, 2000)
"Papaverine is a useful tool to replace pentoxifylline in ICSI programs to select viable spermatozoa in frozen-thawed sperm samples displaying no or very poor motility."1.42Papaverine as a replacement for pentoxifylline to select thawed testicular or epididymal spermatozoa before ICSI. ( Avon, C; Charles, O; Cortvrindt, R; Giorgetti, C; Hans, E; Lazdunski, P; Salzmann, J; Terriou, P, 2015)
"Spermatic cord torsion is a true urological emergency."1.36Comparison of the protective effects of papaverine, lidocaine and verapamil on the sperm quality of the testis after induced torsion-detorsion in rats. ( Afrasiabi, MA; Ardeshiri, M; Karbalay-Doust, S; Monabati, A; Noorafshan, A; Shirazi, M, 2010)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Terriou, P1
Hans, E1
Cortvrindt, R1
Avon, C1
Charles, O1
Salzmann, J1
Lazdunski, P1
Giorgetti, C1
Shirazi, M1
Noorafshan, A1
Karbalay-Doust, S1
Ardeshiri, M1
Afrasiabi, MA1
Monabati, A1
Ozbek, E1
Yurekli, M1
Soylu, A1
Davarci, M1
Balbay, MD1

Trials

1 trial available for papaverine and Sterility, Male

ArticleYear
The role of adrenomedullin in varicocele and impotence.
    BJU international, 2000, Volume: 86, Issue:6

    Topics: Adrenomedullin; Adult; Biomarkers; Erectile Dysfunction; Humans; Infertility, Male; Injections; Male

2000

Other Studies

2 other studies available for papaverine and Sterility, Male

ArticleYear
Papaverine as a replacement for pentoxifylline to select thawed testicular or epididymal spermatozoa before ICSI.
    Gynecologie, obstetrique & fertilite, 2015, Volume: 43, Issue:12

    Topics: Animals; Cell Survival; Cryopreservation; Epididymis; Fertilization in Vitro; Hot Temperature; Human

2015
Comparison of the protective effects of papaverine, lidocaine and verapamil on the sperm quality of the testis after induced torsion-detorsion in rats.
    Scandinavian journal of urology and nephrology, 2010, Volume: 44, Issue:3

    Topics: Anesthetics, Local; Animals; Calcium Channel Blockers; Infertility, Male; Lidocaine; Male; Papaverin

2010