Page last updated: 2024-11-02

papaverine and Spasm

papaverine has been researched along with Spasm in 47 studies

Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.

Spasm: An involuntary contraction of a muscle or group of muscles. Spasms may involve SKELETAL MUSCLE or SMOOTH MUSCLE.

Research Excerpts

ExcerptRelevanceReference
"This study is planned bringing about a new choice for the prophylaxis of RA spasm which is topical iloprost and compares its efficacy with papaverine and diltiazem."9.12An alternative agent for radial arterial graft spasm: application of topical iloprost. ( Besogul, Y; Ikizler, M; Karakaya, A; Ozdemir, C; Sirmagul, B, 2007)
"Fifty-eight patients were randomized into three groups to compare papaverine's ability to prevent spasm and to treat established spasm."9.11Papaverine delivery to the internal mammary artery pedicle effectively treats spasm. ( Crawford, FA; Crumbley, AJ; Girard, DS; Kratz, JM; Sutton, JP; Williams, TH; Zellner, JL, 2004)
"In phenoxybenzamine-treated sections of radial artery, circulating vasoconstrictor agonists may still contribute to the induction of spasm."7.72Phenoxybenzamine treatment is insufficient to prevent spasm in the radial artery: the effect of other vasodilators. ( Chester, MR; Conant, AR; Dihmis, WC; Oo, AY; Shackcloth, MJ; Simpson, AW, 2003)
"We recommend topical use of papaverine at 37 degrees C to relieve intraoperative spasm of the internal thoracic artery."7.69Effect of normothermic papaverine to relieve intraoperative spasm of the internal thoracic artery. ( Bilgen, F; Coruh, T; Ozler, A; Serbetçioğlu, A; Tarhan, IA; Yapici, MF, 1996)
"Papaverine was topically applied on the renal arteries resulting in vasodilation and reperfusion of the kidney."6.58Periarterial papaverine to treat renal artery vasospasm during robot-assisted laparoscopic partial nephrectomy. ( Cadeddu, JA; Sorokin, I; Stevens, SL, 2018)
"This study is planned bringing about a new choice for the prophylaxis of RA spasm which is topical iloprost and compares its efficacy with papaverine and diltiazem."5.12An alternative agent for radial arterial graft spasm: application of topical iloprost. ( Besogul, Y; Ikizler, M; Karakaya, A; Ozdemir, C; Sirmagul, B, 2007)
"Fifty-eight patients were randomized into three groups to compare papaverine's ability to prevent spasm and to treat established spasm."5.11Papaverine delivery to the internal mammary artery pedicle effectively treats spasm. ( Crawford, FA; Crumbley, AJ; Girard, DS; Kratz, JM; Sutton, JP; Williams, TH; Zellner, JL, 2004)
"In phenoxybenzamine-treated sections of radial artery, circulating vasoconstrictor agonists may still contribute to the induction of spasm."3.72Phenoxybenzamine treatment is insufficient to prevent spasm in the radial artery: the effect of other vasodilators. ( Chester, MR; Conant, AR; Dihmis, WC; Oo, AY; Shackcloth, MJ; Simpson, AW, 2003)
"We recommend topical use of papaverine at 37 degrees C to relieve intraoperative spasm of the internal thoracic artery."3.69Effect of normothermic papaverine to relieve intraoperative spasm of the internal thoracic artery. ( Bilgen, F; Coruh, T; Ozler, A; Serbetçioğlu, A; Tarhan, IA; Yapici, MF, 1996)
"Spasm and endothelial injury during harvesting of saphenous vein grafts can be prevented by a protocol that involves perivenous infiltration with 37 degrees C papaverine hydrochloride solution prior to skin incision, initial distention of the vein with the same warm papaverine solution, storage of the distended vein graft in a cold papaverine solution, and maintenance of the vein in the distended state throughout the operative procedure."3.67A clinical technique for prevention of spasm and preservation of endothelium in saphenous vein grafts. ( Haudenschild, CC; LoGerfo, FW; Quist, WC, 1984)
" Methods of harvesting generally cause spasm of the vein and it has been shown that preventing the spasm by applying papaverine improves long-term patency."3.66Early changes in venous arterial autografts: a scanning electron microscope study. ( Belbeck, LW; Gunstensen, J; Julian, J; Richardson, M; Shand, JE, 1983)
"Papaverine was topically applied on the renal arteries resulting in vasodilation and reperfusion of the kidney."2.58Periarterial papaverine to treat renal artery vasospasm during robot-assisted laparoscopic partial nephrectomy. ( Cadeddu, JA; Sorokin, I; Stevens, SL, 2018)
" Thus, the present investigation revealed the phytochemical constituents and explored the detailed pharmacodynamic basis for the curative use of G."1.72The Detailed Pharmacodynamics of the Gut Relaxant Effect and GC-MS Analysis of the ( Ahmad, W; Amir, M; Ansari, MN; Rehman, NU, 2022)
"Papaverine has been used to prevent graft spasm, but its effect is short-lived."1.35Prevention of arterial graft spasm by botulinum toxin: an in-vitro experiment. ( Imaizumi, M; Iwata, H; Murakami, E; Takemura, H, 2009)
"Vasospasm is known to be present during most microvascular procedures."1.27Experimental vasospasm. ( Seaber, AV, 1987)

Research

Studies (47)

TimeframeStudies, this research(%)All Research%
pre-199031 (65.96)18.7374
1990's5 (10.64)18.2507
2000's8 (17.02)29.6817
2010's2 (4.26)24.3611
2020's1 (2.13)2.80

Authors

AuthorsStudies
Rehman, NU1
Ansari, MN1
Ahmad, W1
Amir, M1
Sorokin, I1
Stevens, SL1
Cadeddu, JA1
Sciahbasi, A1
Cuono, A1
Marrangoni, A1
Rigattieri, S1
Yoshizaki, T1
Tabuchi, N1
Toyama, M1
Murakami, E1
Iwata, H1
Imaizumi, M1
Takemura, H1
Conant, AR1
Shackcloth, MJ1
Oo, AY1
Chester, MR1
Simpson, AW1
Dihmis, WC1
DAHLBOM, R1
EDLUND, T1
EKSTRAND, T1
LOHI, A1
ABBEY, P1
AMOROSO, EC2
CONNOLLY, JE2
HADFIELD, GJ2
KINMONTH, JB2
LEE, RH2
HARLACHER, A1
ARRIGONI-MARTELLI, E1
KRAMER, M1
SHEVCHENKO, AI1
ELLIS, PP1
LENDE, RA1
MARKLAND, C1
BYRNE-QUINN, E1
MAYERHOFER, E1
Girard, DS1
Sutton, JP1
Williams, TH1
Crumbley, AJ1
Zellner, JL1
Kratz, JM1
Crawford, FA1
Sanders, LH1
Newman, MA1
Ozdemir, C1
Ikizler, M1
Besogul, Y1
Karakaya, A1
Sirmagul, B1
LoGerfo, FW1
Haudenschild, CC1
Quist, WC1
De Maeyer, P1
Oosterlinck, W1
De Sy, W1
Shand, JE1
Richardson, M1
Belbeck, LW1
Julian, J1
Gunstensen, J1
Feikes, HL1
Roberts, AJ1
Samson, RH1
Gupta, SK1
Scher, LA1
Veith, FJ1
Bilgen, F1
Yapici, MF1
Serbetçioğlu, A1
Tarhan, IA1
Coruh, T1
Ozler, A1
Erdinc, M1
Ocal, A1
Arquilla, B1
Gupta, R1
Gernshiemer, J1
Fischer, M1
Harrison, WE1
Mellor, AJ1
Clark, J1
Singer, DR1
Reuse-Blom, S1
Gabrielian, ES1
Akopov, SE1
Ghazarian, AV1
Hartsock, LA1
Seaber, AV2
Urbaniak, JR1
Valentine, RJ1
Whelan, TV1
Meyers, HF1
Sardo, P1
Cepich, MS1
Giulini, SM1
Zaritsky, A1
Pollak, S1
Frideman, P1
Swarts, Y1
Maitai, CK1
Njoroge, DK1
Munenge, RW1
Agosti, A1
Mantovani, P1
Mori, L1
Göthlin, J1
Olin, T1
Dreikorn, K1
Beduhn, D1
Fournier, AM1
Mourou, M1
Chiousse, E1
László, G1
Kareva, GF1
Kapp, J1
Mahaley, MS1
Odom, GL1
Filipowski, P1
Somorjai, K1
Hahn, F1
Teschendorf, HJ1
Kretzschmar, R1
Gossow, U1
Glanzmann, C1
Upson, JF1
Harrod, DB1
Tanaka, T1
Smyth, EH1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Topical Nitroglycerine Treatment for Radial Artery Spasm Prevention[NCT02832115]Phase 4100 participants (Actual)Interventional2016-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change in Radial Artery Dimension Measured in mm^2.

Change in Radial artery cross sectional area in mm^2 - Before application of topical nitroglycerine / placebo (Pre dilation) vs Prior to arterial puncture after application of topical nitroglycerine / placebo (Post-dilation) (NCT02832115)
Timeframe: Application of nitroglycerine / placebo until prior to arterial puncture. Approximate 60 to 120 minutes

Interventionmm^2 (Mean)
Study2.5
Control-0.2

Number of Patients With Procedural Failure

Need to abort procedure or convert to transfemoral access (NCT02832115)
Timeframe: Intraprocedural: From procedure start to application of radial band. Approximate time 30 to 90 minutes.

InterventionParticipants (Count of Participants)
Study0
Control4

Patient Discomfort or Pain During Procedure (Visual Analog Scale 0-10)

Patient discomfort or pain during procedure measured using Visual analog scale 0-10, 0 being no discomfort or pain (best) and 10 being worst discomfort or pain (worst) (NCT02832115)
Timeframe: Intraprocedural: From procedure start to application of radial band. Approximate time 30 to 90 minutes.

Interventionscore on a scale (Mean)
Study0.792
Control0.875

Radial Artery Spasm

"Incidence of radial artery spasm indicated by a Radial artery spasm score of 1 or more. Radial artery spasm score is sum of:~Intraprocedural pain in the forearm aggravated by movement of the catheter/sheath - Absent :0; Present:1~Difficulty in manipulating the catheter- Absence :0; Present:1~Difficulty with sheath removal: Absent: 0; Present:1~Additional use of intraarterial nitroglycerine or verapamil after the initial vasodilator cocktail- No:0; Yes:1" (NCT02832115)
Timeframe: Intraprocedural: From procedure start to application of radial band. Approximate time 30 to 90 minutes.

InterventionParticipants (Count of Participants)
Study8
Control15

Radial Pulse at End of Procedure

Radial pulse at end of procedure 0- 4+, 0 indicating no palpable pulse (worst); 1 + indicating a faint, but detectable pulse; 2 + suggesting a slightly more diminished pulse than normal; 3 + is a normal pulse; and 4 + indicating a bounding pulse (best). (NCT02832115)
Timeframe: At the end of transradial cardiac catheterization after sheath removal

Interventionscore on a scale (Mean)
Study2.208333333
Control2.166666667

Reviews

1 review available for papaverine and Spasm

ArticleYear
Periarterial papaverine to treat renal artery vasospasm during robot-assisted laparoscopic partial nephrectomy.
    Journal of robotic surgery, 2018, Volume: 12, Issue:1

    Topics: Adult; Humans; Intraoperative Complications; Ischemia; Kidney; Kidney Diseases; Male; Nephrectomy; P

2018

Trials

3 trials available for papaverine and Spasm

ArticleYear
Papaverine delivery to the internal mammary artery pedicle effectively treats spasm.
    The Annals of thoracic surgery, 2004, Volume: 78, Issue:4

    Topics: Arterial Occlusive Diseases; Female; Humans; Injections; Internal Mammary-Coronary Artery Anastomosi

2004
An alternative agent for radial arterial graft spasm: application of topical iloprost.
    Scandinavian cardiovascular journal : SCJ, 2007, Volume: 41, Issue:3

    Topics: Administration, Topical; Aged; Arterial Occlusive Diseases; Coronary Artery Bypass; Diltiazem; Dose-

2007
[Study of the effectivenss of Halidor on surgical patients].
    Orvosi hetilap, 1968, May-26, Volume: 109, Issue:21

    Topics: Cholelithiasis; Clinical Trials as Topic; Cycloheptanes; Fumarates; Humans; Kidney Calculi; Morphine

1968

Other Studies

43 other studies available for papaverine and Spasm

ArticleYear
The Detailed Pharmacodynamics of the Gut Relaxant Effect and GC-MS Analysis of the
    Molecules (Basel, Switzerland), 2022, Dec-14, Volume: 27, Issue:24

    Topics: Animals; Antidiarrheals; Diarrhea; Fruit; Gas Chromatography-Mass Spectrometry; Grewia; Jejunum; Mic

2022
Papaverine use for radial artery sheath entrapment.
    Anatolian journal of cardiology, 2019, Volume: 22, Issue:1

    Topics: Aged; Aged, 80 and over; Female; Humans; Male; Middle Aged; Papaverine; Percutaneous Coronary Interv

2019
Verapamil and nitroglycerin improves the patency rate of radial artery grafts.
    Asian cardiovascular & thoracic annals, 2008, Volume: 16, Issue:5

    Topics: Administration, Topical; Aged; Coronary Artery Bypass; Drug Combinations; Female; Graft Occlusion, V

2008
Prevention of arterial graft spasm by botulinum toxin: an in-vitro experiment.
    Interactive cardiovascular and thoracic surgery, 2009, Volume: 9, Issue:3

    Topics: Animals; Aorta, Abdominal; Aortic Diseases; Botulinum Toxins; Cardiovascular Agents; Dose-Response R

2009
Phenoxybenzamine treatment is insufficient to prevent spasm in the radial artery: the effect of other vasodilators.
    The Journal of thoracic and cardiovascular surgery, 2003, Volume: 126, Issue:2

    Topics: Adrenergic alpha-Agonists; Aged; Angiotensin II; Coronary Artery Bypass; Diltiazem; Dose-Response Re

2003
The activity of 10-amino-acylphenothiazines, basically substituted derivatives of phenothiazine-10-carboxylic acid, atropine, papaverine and some other spasmolytic drugs against barium- and acetylcholine-induced spasms of guinea-pig and rat ileum.
    Acta pharmacologica et toxicologica, 1953, Volume: 9, Issue:2

    Topics: Acetylcholine; Animals; Atropine; Barium; Carboxylic Acids; Guinea Pigs; Ileum; Muscle Relaxants, Ce

1953
Use of papaverine in traumatic arterial spasm after supracondylar fracture of humerus.
    British medical journal, 1955, Dec-31, Volume: 2, Issue:4956

    Topics: Fractures, Bone; Humans; Humeral Fractures; Humerus; Papaverine; Spasm

1955
Traumatic arterial spasm; its relief in man and in monkeys.
    The British journal of surgery, 1956, Volume: 44, Issue:184

    Topics: Animals; Arteries; Disease; Haplorhini; Humans; Male; Papaverine; Spasm; Vascular Diseases

1956
Traumatic arterial spasm; its relief in man and in monkeys.
    The British journal of surgery, 1956, Volume: 44, Issue:184

    Topics: Animals; Arteries; Disease; Haplorhini; Humans; Male; Papaverine; Spasm; Vascular Diseases

1956
Traumatic arterial spasm; its relief in man and in monkeys.
    The British journal of surgery, 1956, Volume: 44, Issue:184

    Topics: Animals; Arteries; Disease; Haplorhini; Humans; Male; Papaverine; Spasm; Vascular Diseases

1956
Traumatic arterial spasm; its relief in man and in monkeys.
    The British journal of surgery, 1956, Volume: 44, Issue:184

    Topics: Animals; Arteries; Disease; Haplorhini; Humans; Male; Papaverine; Spasm; Vascular Diseases

1956
[Postoperative use of the spasmolytic parinokhellin in thoracic surgery].
    Munchener medizinische Wochenschrift (1950), 1957, Aug-23, Volume: 99, Issue:34

    Topics: Humans; Khellin; Papaverine; Parasympatholytics; Postoperative Period; Spasm; Thoracic Surgery; Thor

1957
[Comparative studies of spasmolytic activity in vitro and in vivo].
    Bollettino della Societa italiana di biologia sperimentale, 1958, Sep-30, Volume: 34, Issue:18

    Topics: Atropine; In Vitro Techniques; Muscle Relaxants, Central; Papaverine; Parasympatholytics; Scopolamin

1958
[The effect of various pharmacological substances on the response of smooth muscle to direct electrical stimulation].
    Biulleten' eksperimental'noi biologii i meditsiny, 1962, Volume: 54

    Topics: Anticonvulsants; Atropine; Diphenhydramine; Diphenylacetic Acids; Electric Stimulation; Epinephrine;

1962
INDUCED SPASM IN THE RETINAL ARTERIOLES OF CATS. II. INFLUENCES OF PHYSICAL FACTORS AND DRUGS.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1964, Volume: 71

    Topics: Arterioles; Caffeine; Cats; Epinephrine; Histamine; Neostigmine; Niacinamide; Norepinephrine; Papave

1964
RENAL ARTERY SPASM.
    The Journal of urology, 1964, Volume: 91

    Topics: Animals; Histology; Kidney; Papaverine; Procaine; Rabbits; Renal Artery; Research; Spasm; Vascular D

1964
PROLONGED ARTERIOSPASM AFTER OVERDOSE OF ORAL ERGOTAMINE TARTRATE IN MIGRAINE.
    British medical journal, 1964, Aug-29, Volume: 2, Issue:5408

    Topics: Anticoagulants; Arteries; Ergotamine; Humans; Migraine Disorders; Papaverine; Poisoning; Spasm; Toxi

1964
[36 years' experience with the use of papaverine in the treatment of pyloric spasm in younger infants and in the newborn].
    Annales paediatrici. International review of pediatrics, 1951, Volume: 176, Issue:2

    Topics: Humans; Infant; Infant, Newborn; Papaverine; Pylorus; Spasm

1951
Intractable postoperative internal thoracic artery spasm managed with angiographic intraluminal papaverine.
    The Journal of thoracic and cardiovascular surgery, 2005, Volume: 130, Issue:3

    Topics: Aged; Aged, 80 and over; Female; Humans; Injections, Intra-Arterial; Internal Mammary-Coronary Arter

2005
A clinical technique for prevention of spasm and preservation of endothelium in saphenous vein grafts.
    Archives of surgery (Chicago, Ill. : 1960), 1984, Volume: 119, Issue:10

    Topics: Blood Vessel Prosthesis; Humans; Microscopy, Electron, Scanning; Papaverine; Saphenous Vein; Spasm;

1984
Prevention of vasospasms during extensive renal surgery. An experimental study in rats.
    European urology, 1981, Volume: 7, Issue:4

    Topics: Animals; Kidney; Male; Mannitol; Papaverine; Perfusion; Phenoxybenzamine; Preoperative Care; Rats; R

1981
Early changes in venous arterial autografts: a scanning electron microscope study.
    Canadian journal of surgery. Journal canadien de chirurgie, 1983, Volume: 26, Issue:2

    Topics: Animals; Arteries; Dogs; Endothelium; Female; Male; Microscopy, Electron, Scanning; Papaverine; Spas

1983
Harvesting and protection of the saphenous vein associated with early delivery of blood cardioplegia in coronary artery bypass graft surgery.
    American heart journal, 1982, Volume: 104, Issue:2 Pt 1

    Topics: Constriction; Coronary Artery Bypass; Heart Arrest, Induced; Humans; Myocardial Revascularization; P

1982
Arterial spasm complicating distal vascular bypass procedures.
    Archives of surgery (Chicago, Ill. : 1960), 1982, Volume: 117, Issue:7

    Topics: Aged; Arteries; Female; Humans; Leg; Male; Middle Aged; Papaverine; Postoperative Complications; Rad

1982
Effect of normothermic papaverine to relieve intraoperative spasm of the internal thoracic artery.
    The Annals of thoracic surgery, 1996, Volume: 62, Issue:3

    Topics: Administration, Topical; Adult; Aged; Blood Flow Velocity; Coronary Artery Bypass; Female; Humans; I

1996
Internal thoracic artery spasm and normothermic papaverine.
    The Annals of thoracic surgery, 1997, Volume: 64, Issue:4

    Topics: Coronary Artery Bypass; Humans; Hypothermia; Mammary Arteries; Papaverine; Spasm; Vasoconstriction;

1997
Acute arterial spasm in an extremity caused by inadvertent intra-arterial injection successfully treated in the emergency department.
    The Journal of emergency medicine, 2000, Volume: 19, Issue:2

    Topics: Adult; Alcohol Withdrawal Delirium; Angiography; Anti-Anxiety Agents; Arm; Brachial Artery; Chlordia

2000
Vasodilator pre-treatment of human radial arteries; comparison of effects of phenoxybenzamine vs papaverine on norepinephrine-induced contraction in vitro.
    European heart journal, 2001, Volume: 22, Issue:23

    Topics: Aged; Analysis of Variance; Coronary Artery Bypass; Female; Humans; Male; Middle Aged; Papaverine; P

2001
Action of papaverine on serum-induced spasms in cerebral arterioles.
    Bibliotheca anatomica, 1979, Issue:18

    Topics: Animals; Arterioles; Blood; Cerebrovascular Circulation; Papaverine; Rabbits; Spasm; Time Factors; V

1979
Cerebral-artery spasm in vitro.
    Lancet (London, England), 1990, Jan-13, Volume: 335, Issue:8681

    Topics: Arteriosclerosis; Cerebral Arteries; Dinoprost; Humans; In Vitro Techniques; Muscle Contraction; Nif

1990
Inhibition of epinephrine-induced vasospasm with adrenoreceptor blockade in the rat cremaster muscle.
    Microsurgery, 1991, Volume: 12, Issue:1

    Topics: Animals; Arteries; Epinephrine; Male; Muscles; Papaverine; Phentolamine; Rats; Receptors, Adrenergic

1991
Nonocclusive mesenteric ischemia in renal patients: recognition and prevention of intestinal gangrene.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1990, Volume: 15, Issue:6

    Topics: Aged; Humans; Infarction; Intestines; Ischemia; Kidney Failure, Chronic; Male; Mesenteric Arteries;

1990
Experimental vasospasm.
    Microsurgery, 1987, Volume: 8, Issue:4

    Topics: Animals; Electromagnetic Phenomena; Lidocaine; Microsurgery; Muscles; Papaverine; Parasympatholytics

1987
[Diagnostic and therapeutic role of angiography in acute vascular insufficiency of the superior mesenteric artery].
    La Radiologia medica, 1988, Volume: 75, Issue:4

    Topics: Aged; Embolism; Female; Humans; Injections, Intra-Arterial; Male; Mesenteric Arteries; Mesenteric Va

1988
[Reactive vasospasm in the newborn treated by papaverine infusion].
    Harefuah, 1987, May-01, Volume: 112, Issue:9

    Topics: Catheterization; Humans; Infant, Low Birth Weight; Infant, Newborn; Infusions, Intra-Arterial; Ische

1987
A comparative study of two antispasmodic products: Buscopan and NO-Spa.
    East African medical journal, 1985, Volume: 62, Issue:7

    Topics: Animals; Butylscopolammonium Bromide; Disease Models, Animal; Guinea Pigs; Ileal Diseases; Papaverin

1985
Action of caerulein and related substances on the sphincter of Oddi.
    Naunyn-Schmiedebergs Archiv fur Pharmakologie, 1971, Volume: 268, Issue:1

    Topics: Ampulla of Vater; Animals; Bile Ducts; Cattle; Cholecystokinin; Depression, Chemical; Drug Antagonis

1971
Traumatic arterial spasm. An angiographic study in rabbits.
    Acta radiologica: diagnosis, 1970, Volume: 10, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Anesthesia, Conduction; Anesthetics, Local;

1970
[Treatment of renal vasospasm in shock (author's transl)].
    Urologia internationalis, 1973, Volume: 28, Issue:3

    Topics: Angiography; Animals; Cadaver; Dogs; Humans; Kidney; Kidney Transplantation; Papaverine; Phenoxybenz

1973
[Nafditrofuryl and carotid spasms].
    Journal de radiologie, d'electrologie, et de medecine nucleaire, 1972, Volume: 53, Issue:12

    Topics: Carotid Artery Diseases; Cerebral Angiography; Child; Diagnosis, Differential; Ethylamines; Furans;

1972
[The effect of pharmacologic agents coronary circulation in experimental spasms of heart vessels].
    Vestnik Akademii meditsinskikh nauk SSSR, 1963, Volume: 18, Issue:1

    Topics: Animals; Blood Circulation; Cats; Coronary Vessels; Methods; Morphine; Nitroglycerin; Papaverine; Ph

1963
Experimental evaluation of potential spasmolytic drugs.
    Journal of neurosurgery, 1970, Volume: 32, Issue:4

    Topics: Animals; Cats; Choline; Isosorbide Dinitrate; Magnesium Sulfate; Papaverine; Parasympatholytics; Pho

1970
[The antiallergic activity of tritoqualine].
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:10

    Topics: Anaphylaxis; Animals; Asthma; Barium; Benzofurans; Gastric Juice; Guinea Pigs; Heart; Histamine; Ile

1970
The influence of spasm on small arterial anastomoses.
    The Journal of surgical research, 1968, Volume: 8, Issue:3

    Topics: Animals; Arteries; Brachial Artery; Dogs; Femoral Artery; Papaverine; Spasm; Sympathectomy

1968
[Experimental study on cerebral angiospasm, with special reference to the intracranial vertebro-basilar system].
    Shinkei kenkyu no shimpo. Advances in neurological sciences, 1968, Volume: 12, Issue:2

    Topics: Acetylcholine; Animals; Basilar Artery; Cats; Cerebral Angiography; Mesenteric Arteries; Papaverine;

1968
Major arterial injury in closed fracture of the neck of the humerus. Report of a case.
    The Journal of bone and joint surgery. British volume, 1969, Volume: 51, Issue:3

    Topics: Aged; Amputation, Surgical; Arm; Axillary Artery; Brachial Artery; Female; Forearm; Gangrene; Humans

1969