papaverine has been researched along with Sleep Wake Disorders in 5 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Sleep Wake Disorders: Abnormal sleep-wake schedule or pattern associated with the CIRCADIAN RHYTHM which affect the length, timing, and/or rigidity of the sleep-wake cycle relative to the day-night cycle.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| DENNEMARK, HG | 1 |
| HARRER, G | 1 |
| Feine-Haake, G | 1 |
| Neiss, A | 1 |
| Weinert, W | 1 |
| Agnoli, A | 2 |
| Piccinelli, A | 1 |
| Neri, G | 1 |
2 trials available for papaverine and Sleep Wake Disorders
| Article | Year |
|---|---|
[The treatment of cerebrovascular insufficiency. Their evaluation in a double-blind study].
Topics: Aged; Aging; Cerebrovascular Disorders; Clinical Trials as Topic; Confusion; Drug Combinations; Drug | 1975 |
[Long-term medical treatment of acute cerebrovascular disease sequelae (comparison papaverine-piribedil].
Topics: Cerebrovascular Circulation; Cerebrovascular Disorders; Clinical Trials as Topic; Dioxoles; Drug Eva | 1974 |
3 other studies available for papaverine and Sleep Wake Disorders
| Article | Year |
|---|---|
[Medical treatment of nervous rhythm disorders, especially dies inversus].
Topics: Humans; Lobelia; Nervous System Diseases; Nitrites; Papaverine; Parasympathomimetics; Phenobarbital; | 1958 |
[ON THE TREATMENT OF SLEEP DISORDERS IN OLD AGE].
Topics: Amobarbital; Geriatrics; Humans; Papaverine; Salicylamides; Secobarbital; Sleep Wake Disorders | 1963 |
[Problems in the long-term medical treatment of sequelae of acute cerebrovascular diseases. Double-blind studies].
Topics: Cerebrovascular Disorders; Cognition Disorders; Emotions; Headache; Humans; Mental Processes; Motor | 1976 |