papaverine has been researched along with Shock, Septic in 4 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Shock, Septic: Sepsis associated with HYPOTENSION or hypoperfusion despite adequate fluid resuscitation. Perfusion abnormalities may include but are not limited to LACTIC ACIDOSIS; OLIGURIA; or acute alteration in mental status.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Papaverine was administered as an intravenous bolus injection after systemic hemodynamic stabilization had been achieved by means of fluid resuscitation combined with dopamine and/or norepinephrine vasopressor medication." | 2.80 | Papaverine improves sublingual blood flow in patients with septic shock. ( Li, H; Wang, Z; Yao, G; Zhu, X, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, H | 1 |
| Zhu, X | 1 |
| Yao, G | 1 |
| Wang, Z | 1 |
| Carol, W | 1 |
| Parfitt, VJ | 1 |
| Wong, R | 1 |
| Dobbie, A | 1 |
| Hartog, M | 1 |
| Gingell, JC | 1 |
| Giertz, H | 1 |
| Hahn, F | 1 |
| Bernauer, W | 1 |
1 trial available for papaverine and Shock, Septic
| Article | Year |
|---|---|
Papaverine improves sublingual blood flow in patients with septic shock.
Topics: Aged; Aged, 80 and over; Female; Hemodynamics; Humans; Male; Microcirculation; Mouth Mucosa; Papaver | 2015 |
3 other studies available for papaverine and Shock, Septic
| Article | Year |
|---|---|
[Obstetrical emergencies, concerning the mother].
Topics: Acute Kidney Injury; Blood Coagulation Disorders; Calcium; Embolism, Amniotic Fluid; Emergencies; Fe | 1975 |
Staphylococcal septicaemia complicating intracavernosal autoinjection therapy for impotence in a man with diabetes.
Topics: Bacteremia; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Erectile Dysfunction; Floxacillin; | 1992 |
On the cause of the different sensitivity to antihistaminics (mepyramine) of anaphylactic, histamine, and anaphylatoxin shock.
Topics: Anaphylaxis; Animals; Bronchi; Bronchial Spasm; Guinea Pigs; Histamine; Histamine H1 Antagonists; Lu | 1968 |