papaverine has been researched along with Schizophrenia in 2 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Menniti, FS | 1 |
| Chappie, TA | 1 |
| Humphrey, JM | 1 |
| Schmidt, CJ | 1 |
| Lambert, PA | 1 |
| Bouchardy, M | 1 |
1 review available for papaverine and Schizophrenia
| Article | Year |
|---|---|
Phosphodiesterase 10A inhibitors: a novel approach to the treatment of the symptoms of schizophrenia.
Topics: Corpus Striatum; Humans; Models, Biological; Molecular Structure; Papaverine; Phosphodiesterase Inhi | 2007 |
1 other study available for papaverine and Schizophrenia
| Article | Year |
|---|---|
[Can psychiatric disorders on the aged be influenced by affecting the cerebral circulation?].
Topics: Aged; Cerebrovascular Disorders; Dementia; Ergot Alkaloids; Female; Humans; Male; Middle Aged; Neuro | 1968 |