papaverine has been researched along with Renal Colic in 4 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Renal Colic: A severe intermittent and spasmodic pain in the lower back radiating to the groin, scrotum, and labia which is most commonly caused by a kidney stone (RENAL CALCULUS) passing through the URETER or by other urinary track blockage. It is often associated with nausea, vomiting, fever, restlessness, dull pain, frequent urination, and HEMATURIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This trial aims to compare a single-dose of Spasmofen rectal suppository to a single intravenous (IV) ketorolac tromethamine 30 mg/2 mL dose in patients with acute renal colic." | 9.19 | Clinical efficacy of Spasmofen® suppository in the emergency treatment of renal colic: a randomized, double-blind, double-dummy comparative trial. ( Helmy, S; Salem, A; Yakoot, M; Yousef, S, 2014) |
| "To evaluate the analgesic efficacy and safety of intramuscular drotaverine hydrochloride vs diclofenac sodium in treatment of acute renal colic." | 9.16 | Intramuscular drotaverine and diclofenac in acute renal colic: a comparative study of analgesic efficacy and safety. ( Akantappa Bandakkanavar, TK; Arora, P; Dash, A; Maiti, R, 2012) |
| " papaverine hydrochloride plus a diclofenac suppository were more effective than the diclofenac suppository alone for treating acute renal colic." | 9.16 | Treatment of loin pain suspected to be renal colic with papaverine hydrochloride: a prospective double-blind randomised study. ( Asgari, SA; Asli, MM; Aval, HB; Enshaei, A; Esmaeili, S; Farzan, A; Ghanaei, MM; Madani, AH; Maghsoudi, PA; Shakiba, M, 2012) |
| " This trial aims to compare a single-dose of Spasmofen rectal suppository to a single intravenous (IV) ketorolac tromethamine 30 mg/2 mL dose in patients with acute renal colic." | 5.19 | Clinical efficacy of Spasmofen® suppository in the emergency treatment of renal colic: a randomized, double-blind, double-dummy comparative trial. ( Helmy, S; Salem, A; Yakoot, M; Yousef, S, 2014) |
| "To evaluate the analgesic efficacy and safety of intramuscular drotaverine hydrochloride vs diclofenac sodium in treatment of acute renal colic." | 5.16 | Intramuscular drotaverine and diclofenac in acute renal colic: a comparative study of analgesic efficacy and safety. ( Akantappa Bandakkanavar, TK; Arora, P; Dash, A; Maiti, R, 2012) |
| " papaverine hydrochloride plus a diclofenac suppository were more effective than the diclofenac suppository alone for treating acute renal colic." | 5.16 | Treatment of loin pain suspected to be renal colic with papaverine hydrochloride: a prospective double-blind randomised study. ( Asgari, SA; Asli, MM; Aval, HB; Enshaei, A; Esmaeili, S; Farzan, A; Ghanaei, MM; Madani, AH; Maghsoudi, PA; Shakiba, M, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yakoot, M | 1 |
| Salem, A | 1 |
| Yousef, S | 1 |
| Helmy, S | 1 |
| Dash, A | 1 |
| Maiti, R | 1 |
| Akantappa Bandakkanavar, TK | 1 |
| Arora, P | 1 |
| Asgari, SA | 1 |
| Asli, MM | 1 |
| Madani, AH | 1 |
| Maghsoudi, PA | 1 |
| Ghanaei, MM | 1 |
| Shakiba, M | 1 |
| Aval, HB | 1 |
| Enshaei, A | 1 |
| Farzan, A | 1 |
| Esmaeili, S | 1 |
| RUTISHAUSER, G | 1 |
3 trials available for papaverine and Renal Colic
| Article | Year |
|---|---|
Clinical efficacy of Spasmofen® suppository in the emergency treatment of renal colic: a randomized, double-blind, double-dummy comparative trial.
Topics: Administration, Rectal; Adult; Codeine; Double-Blind Method; Drug Combinations; Emergency Treatment; | 2014 |
Intramuscular drotaverine and diclofenac in acute renal colic: a comparative study of analgesic efficacy and safety.
Topics: Adult; Analgesics; Diclofenac; Female; Humans; Injections, Intramuscular; Male; Pain Measurement; Pa | 2012 |
Treatment of loin pain suspected to be renal colic with papaverine hydrochloride: a prospective double-blind randomised study.
Topics: Acute Disease; Acute Pain; Adolescent; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; D | 2012 |
1 other study available for papaverine and Renal Colic
| Article | Year |
|---|---|
[On the pathogenesis of ureteral colic].
Topics: Humans; Kidney Diseases; Papaverine; Renal Colic; Ureteral Obstruction | 1962 |