papaverine has been researched along with Renal Artery Stenosis in 11 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study was to assess the hyperemic effects of papaverine and dopamine in the renal microcirculation of hypertensive patients with renal artery stenosis (RAS)." | 7.81 | Comparison of the renal hyperemic effects of papaverine and dopamine in patients with renal artery stenosis. ( Derkacz, A; Gosławska, K; Mazur, G; Mysiak, A; Początek, K; Podgórski, M; Poręba, R; Protasiewicz, M; Szymańska-Chabowska, A; Witkowski, A, 2015) |
| " Resting Pd/Pa ratio (ratio of mean distal to lesion and mean proximal pressures) and translesional systolic pressure gradient were obtained and FFR and hyperemic translesional systolic and mean pressure gradients (HSG and HMG) were registered after papaverine induced maximum hyperemia-pre and poststent implantation." | 3.88 | Initial experience with the use of fractional flow reserve in the hemodynamic evaluation of transplant renal artery stenosis. ( Alves, CMR; Barbosa, AHP; Batista, MC; Caixeta, A; Carvalho, AC; Gomes Júnior, MPM; Pestana, JOM, 2018) |
| "The purpose of this study was to assess the hyperemic effects of papaverine and dopamine in the renal microcirculation of hypertensive patients with renal artery stenosis (RAS)." | 3.81 | Comparison of the renal hyperemic effects of papaverine and dopamine in patients with renal artery stenosis. ( Derkacz, A; Gosławska, K; Mazur, G; Mysiak, A; Początek, K; Podgórski, M; Poręba, R; Protasiewicz, M; Szymańska-Chabowska, A; Witkowski, A, 2015) |
| "Physiological assessment of renal artery stenosis using Pd/Pa ratio and papaverine- induced renal fractional fl ow reserve did not predict hypertension response after renal artery stenting." | 3.79 | Prognostic value of renal fractional flow reserve in blood pressure response after renal artery stenting (PREFER study). ( Florczak, E; Januszewicz, A; Januszewicz, M; Kądziela, J; Kalińczuk, Ł; Michałowska, I; Norwa-Otto, B; Prejbisz, A; Warchoł, E; Witkowski, A, 2013) |
| " Intrarenal papaverine neither prolonged the QT interval nor induced ventricular arrhythmias and the safety of which will need to be corroborated in a large study." | 3.76 | Physiological assessment of renal artery stenosis: comparisons of resting with hyperemic renal pressure measurements. ( Fahsah, I; Jevans, AJ; Kapoor, N; Karim, R; Leesar, MA, 2010) |
| "Hyperemia was induced by administration of intrarenal papavarine." | 1.33 | Renal fractional flow reserve: a hemodynamic evaluation of moderate renal artery stenoses. ( Almagor, Y; Bashir, R; Meerkin, D; Rosenfield, K; Shalman, E; Subramanian, R; White, CJ, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (27.27) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 5 (45.45) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gomes Júnior, MPM | 1 |
| Alves, CMR | 1 |
| Barbosa, AHP | 1 |
| Caixeta, A | 1 |
| Batista, MC | 1 |
| Pestana, JOM | 1 |
| Carvalho, AC | 1 |
| Kądziela, J | 1 |
| Januszewicz, A | 1 |
| Prejbisz, A | 1 |
| Michałowska, I | 1 |
| Januszewicz, M | 1 |
| Florczak, E | 1 |
| Kalińczuk, Ł | 1 |
| Norwa-Otto, B | 1 |
| Warchoł, E | 1 |
| Witkowski, A | 2 |
| Protasiewicz, M | 1 |
| Początek, K | 1 |
| Poręba, R | 1 |
| Derkacz, A | 1 |
| Podgórski, M | 1 |
| Gosławska, K | 1 |
| Szymańska-Chabowska, A | 1 |
| Mazur, G | 1 |
| Mysiak, A | 1 |
| Kapoor, N | 1 |
| Fahsah, I | 1 |
| Karim, R | 1 |
| Jevans, AJ | 1 |
| Leesar, MA | 1 |
| Kern, MJ | 1 |
| Mounier-Vehier, C | 1 |
| Cocheteux, B | 1 |
| Haulon, S | 1 |
| Devos, P | 1 |
| Lions, C | 1 |
| Gautier, C | 1 |
| Carre, A | 1 |
| Beregi, JP | 1 |
| Subramanian, R | 1 |
| White, CJ | 1 |
| Rosenfield, K | 1 |
| Bashir, R | 1 |
| Almagor, Y | 1 |
| Meerkin, D | 1 |
| Shalman, E | 1 |
| Slovut, DP | 1 |
| Lookstein, R | 1 |
| Bacharach, JM | 1 |
| Olin, JW | 1 |
| Honda, N | 1 |
| Morikawa, A | 1 |
| Nihei, H | 1 |
| Aizawa, C | 1 |
| Yoshitoshi, Y | 1 |
| Amplatz, K | 1 |
| Labay, P | 1 |
| Boyarsky, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prognostic Value of Renal Fractional Flow Reserve in Hypertensive Patients With Renal Artery Stenosis Qualified to Renal Artery Stenting[NCT01128933] | 45 participants (Actual) | Interventional | 2006-06-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
11 other studies available for papaverine and Renal Artery Stenosis
| Article | Year |
|---|---|
Initial experience with the use of fractional flow reserve in the hemodynamic evaluation of transplant renal artery stenosis.
Topics: Adult; Angioplasty, Balloon; Catheterization, Peripheral; Computed Tomography Angiography; Female; H | 2018 |
Prognostic value of renal fractional flow reserve in blood pressure response after renal artery stenting (PREFER study).
Topics: Aged; Angioplasty; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Female; Humans; Hypertensi | 2013 |
Comparison of the renal hyperemic effects of papaverine and dopamine in patients with renal artery stenosis.
Topics: Aged; Dopamine; Female; Humans; Hyperemia; Kidney; Male; Microcirculation; Middle Aged; Papaverine; | 2015 |
Physiological assessment of renal artery stenosis: comparisons of resting with hyperemic renal pressure measurements.
Topics: Aged; Aorta; Arrhythmias, Cardiac; Biomarkers; Blood Pressure; Blood Pressure Determination; Chi-Squ | 2010 |
Can we apply coronary physiologic methods to renal artery stenosis assessment?
Topics: Biomarkers; Blood Pressure; Blood Pressure Determination; Coronary Circulation; Coronary Stenosis; H | 2010 |
Changes in renal blood flow reserve after angioplasty of renal artery stenosis in hypertensive patients.
Topics: Aged; Angioplasty, Balloon; Female; Humans; Hypertension, Renal; Male; Middle Aged; Papaverine; Rena | 2004 |
Renal fractional flow reserve: a hemodynamic evaluation of moderate renal artery stenoses.
Topics: Aged; Angiography; Cohort Studies; Female; Hemodynamics; Humans; Hyperemia; Linear Models; Male; Mid | 2005 |
Correlation between noninvasive and endovascular Doppler in patients with atherosclerotic renal artery stenosis: a pilot study.
Topics: Aged; Aged, 80 and over; Analysis of Variance; Arteriosclerosis; Comorbidity; Endosonography; Female | 2006 |
Postocclusive vascular responses in isolated perfused kidney of rabbits.
Topics: Acetylcholine; Angiotensin II; Animals; Atropine; Carbon Dioxide; Constriction; Dilatation; Hydrogen | 1972 |
Angiography in assessing renovascular hypertension: past and present.
Topics: Angiography; Arteriosclerosis; Arteriovenous Fistula; Catheterization; Child; Contrast Media; Histor | 1974 |
Ureteral peristaltic response to renal compression and other maneuvers: renal-ureteral coupling as a physiological concept.
Topics: Animals; Diuresis; Dogs; Isoproterenol; Kidney; Kidney Cortex; Kidney Pelvis; Papaverine; Phenoxyben | 1973 |