papaverine has been researched along with Pulmonary Edema in 13 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Pulmonary Edema: Excessive accumulation of extravascular fluid in the lung, an indication of a serious underlying disease or disorder. Pulmonary edema prevents efficient PULMONARY GAS EXCHANGE in the PULMONARY ALVEOLI, and can be life-threatening.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hypocapnia/alkalosis is a consequence of several lung and metabolic pathologies." | 1.35 | [Effect of hypocapnia/alkalosis on the fluid filtration rate in isolated and perfused rabbit lungs]. ( Caraballo, JC; Castro, I; Gutiérrez, J; Pezzulo, A; Sánchez-de León, R; Trejo, H; Urich, D, 2008) |
| "These findings indicate that H2O2 causes pulmonary edema by elevating hydrostatic pressure and increasing vascular permeability." | 1.31 | Activation of rho is involved in the mechanism of hydrogen-peroxide-induced lung edema in isolated perfused rabbit lung. ( Chiba, Y; Ishii, Y; Kitamura, S; Sugiyama, Y, 2001) |
| "In papaverine-treated rabbits, all arterioles dilated and a larger increase in perivascular interstitial thickness was observed." | 1.31 | Pulmonary microvascular and perivascular interstitial geometry during development of mild hydraulic edema. ( Bettinelli, D; Boschetti, F; Candiani, A; Crisafulli, B; Del Fabbro, M; Miserocchi, G; Negrini, D, 2001) |
| "This reaction was accompanied by pulmonary edema." | 1.29 | Role of neuropeptides in acetylcholine-induced edema in isolated and perfused rabbit lungs. ( Ansay, M; Delaunois, A; Gustin, P, 1993) |
| "The results indicate that IL-2 causes pulmonary edema secondary to an increase in Ppc." | 1.28 | IL-2 induces pulmonary edema and vasoconstriction independent of circulating lymphocytes. ( Everitt, J; Ferro, TJ; Johnson, A; Malik, AB, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (53.85) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 4 (30.77) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Urich, D | 2 |
| Trejo, H | 1 |
| Pezzulo, A | 1 |
| Caraballo, JC | 2 |
| Gutiérrez, J | 2 |
| Castro, I | 1 |
| Sánchez-de León, R | 1 |
| Trejo, HE | 1 |
| Pezzulo, AA | 1 |
| Castro, IJ | 1 |
| Centeno, GR | 1 |
| Sánchez de León, R | 1 |
| Delaunois, A | 1 |
| Gustin, P | 1 |
| Ansay, M | 1 |
| Fike, CD | 1 |
| Kaplowitz, MR | 1 |
| Chiba, Y | 1 |
| Ishii, Y | 1 |
| Kitamura, S | 1 |
| Sugiyama, Y | 1 |
| Negrini, D | 1 |
| Candiani, A | 1 |
| Boschetti, F | 1 |
| Crisafulli, B | 1 |
| Del Fabbro, M | 1 |
| Bettinelli, D | 1 |
| Miserocchi, G | 1 |
| Kurygin, GV | 1 |
| Kopylov, VN | 1 |
| Heffner, JE | 1 |
| Cook, JA | 1 |
| Halushka, PV | 1 |
| Ferro, TJ | 1 |
| Johnson, A | 2 |
| Everitt, J | 1 |
| Malik, AB | 1 |
| Lamm, WJ | 1 |
| Luchtel, D | 1 |
| Albert, RK | 1 |
| Raj, JU | 1 |
| Chen, P | 1 |
| Shasby, DM | 1 |
| Shasby, SS | 1 |
| Peach, MJ | 1 |
13 other studies available for papaverine and Pulmonary Edema
| Article | Year |
|---|---|
[Effect of hypocapnia/alkalosis on the fluid filtration rate in isolated and perfused rabbit lungs].
Topics: Adrenergic beta-Agonists; Alkalosis; Animals; Anti-Inflammatory Agents; Blood Pressure; Fenoterol; F | 2008 |
Beneficial effects of hydrocortisone and papaverine on a model of pulmonary embolism induced by autologous blood clots in isolated and perfused rabbit lungs.
Topics: Animals; Anti-Inflammatory Agents; Disease Models, Animal; Hemodynamics; Hydrocortisone; In Vitro Te | 2007 |
Role of neuropeptides in acetylcholine-induced edema in isolated and perfused rabbit lungs.
Topics: Acetylcholine; Animals; Arachidonic Acid; Capillary Permeability; Capsaicin; Female; Male; Neuropept | 1993 |
Effect of airway and left atrial pressures on microvascular and interstitial pressures in adult lungs.
Topics: Air Pressure; Animals; Atrial Function; Blood Gas Analysis; Blood Pressure; Extracellular Space; Hea | 1993 |
Activation of rho is involved in the mechanism of hydrogen-peroxide-induced lung edema in isolated perfused rabbit lung.
Topics: Amides; Animals; Blood Pressure; Capillaries; Capillary Permeability; Enzyme Inhibitors; Hydrogen Pe | 2001 |
Pulmonary microvascular and perivascular interstitial geometry during development of mild hydraulic edema.
Topics: Animals; Blood Pressure; Extracellular Space; Microcirculation; Papaverine; Pulmonary Alveoli; Pulmo | 2001 |
[Prevention of acute pulmonary edema in irradiated organisms].
Topics: Aminocaproic Acid; Animals; Chloramines; Dihydroergotoxine; Female; Insulin; Male; Papaverine; Pulmo | 1977 |
Human platelets modulate edema formation in isolated rabbit lungs.
Topics: Animals; Aspirin; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Dehydroepiandrosterone; | 1989 |
IL-2 induces pulmonary edema and vasoconstriction independent of circulating lymphocytes.
Topics: Animals; Capillary Permeability; Endothelium, Vascular; Female; Guinea Pigs; Imidazoles; In Vitro Te | 1989 |
PMA-induced pulmonary edema: mechanisms of the vasoactive response.
Topics: Animals; Blood Pressure; Capillary Permeability; Female; Guinea Pigs; Male; Papaverine; Perfusion; P | 1988 |
Sites of leakage in three models of acute lung injury.
Topics: Animals; Arteries; Arterioles; Blood Pressure; Capillary Permeability; Disease Models, Animal; Embol | 1988 |
Effect of edema on segmental vascular resistance in isolated lamb lungs determined by micropuncture.
Topics: Animals; Animals, Newborn; Blood Pressure; In Vitro Techniques; Microcirculation; Microspheres; Orga | 1987 |
Polymorphonuclear leukocyte: arachidonate edema.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Catalase; Catechols; Endothelium; Epoprosteno | 1985 |