papaverine has been researched along with Prostatic Neoplasms in 6 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Prostatic Neoplasms: Tumors or cancer of the PROSTATE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The intracorporeal injection of papaverine (ICP) is now a well recognized therapeutic option in the management of impotence." | 5.06 | Intracorporeal papaverine injection in androgen deprived men. ( Desai, KM; Gilbert, HW; Gillatt, DA; Gingell, JC, 1990) |
| "Men with impotence of any etiology have been entered on a program to evaluate prospectively the efficacy of intracavernosal injection of vasoactive compounds in producing a satisfactory erection with pharmacologic means." | 2.67 | Pharmacologic erection with intracavernosal injection for men with sexual dysfunction following irradiation: a preliminary report. ( English, W; Goodman, RL; Hanno, PM; Pierce, LJ; Wein, AJ; Whittington, R, 1991) |
| "Three human prostate cancer cell lines PC-3, DU145 and LNCaP were treated with one of the phosphodiesterase inhibitors, papaverine, 3-isobutyl-1-methylxanthine (IBMX) or theophylline, for 6 days." | 1.30 | The effect of papaverine on morphologic differentiation, proliferation and invasive potential of human prostatic cancer LNCaP cells. ( Goto, T; Hida, A; Hosaka, Y; Kasuya, Y; Kawabe, K; Kitamura, T; Matsushima, H; Ohta, Y; Simizu, T; Takeda, K, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Musialik, E | 1 |
| Ryszawy, D | 1 |
| Madeja, Z | 1 |
| Korohoda, W | 1 |
| Goto, T | 1 |
| Matsushima, H | 1 |
| Kasuya, Y | 1 |
| Hosaka, Y | 1 |
| Kitamura, T | 1 |
| Kawabe, K | 1 |
| Hida, A | 1 |
| Ohta, Y | 1 |
| Simizu, T | 1 |
| Takeda, K | 1 |
| Baniel, J | 1 |
| Israilov, S | 1 |
| Segenreich, E | 1 |
| Livne, PM | 1 |
| Pierce, LJ | 1 |
| Whittington, R | 1 |
| Hanno, PM | 1 |
| English, W | 1 |
| Wein, AJ | 1 |
| Goodman, RL | 1 |
| Gilbert, HW | 1 |
| Gillatt, DA | 1 |
| Desai, KM | 1 |
| Gingell, JC | 1 |
| Brosman, S | 1 |
2 trials available for papaverine and Prostatic Neoplasms
| Article | Year |
|---|---|
Pharmacologic erection with intracavernosal injection for men with sexual dysfunction following irradiation: a preliminary report.
Topics: Adenoma; Aged; Erectile Dysfunction; Humans; Male; Middle Aged; Papaverine; Penile Erection; Phentol | 1991 |
Intracorporeal papaverine injection in androgen deprived men.
Topics: Erectile Dysfunction; Humans; Injections; Libido; Male; Multicenter Studies as Topic; Papaverine; Pe | 1990 |
4 other studies available for papaverine and Prostatic Neoplasms
| Article | Year |
|---|---|
Morpho-physiological heterogeneity of cells within two rat prostate carcinoma cell lines AT-2 and MAT-LyLu differing in the degree of malignancy observed by cell cloning and the effects of caffeine, theophylline and papaverine upon a proportion of the clo
Topics: Animals; Caffeine; Cell Line, Tumor; Cell Movement; Clone Cells; Connexin 43; Male; Neoplasm Invasiv | 2013 |
The effect of papaverine on morphologic differentiation, proliferation and invasive potential of human prostatic cancer LNCaP cells.
Topics: 1-Methyl-3-isobutylxanthine; Cell Differentiation; Cell Division; Cell Size; Cyclic AMP; Diffusion C | 1999 |
Comparative evaluation of treatments for erectile dysfunction in patients with prostate cancer after radical retropubic prostatectomy.
Topics: Aged; Erectile Dysfunction; Humans; Injections; Male; Middle Aged; Papaverine; Phosphodiesterase Inh | 2001 |
The management of impotence following pelvic surgery.
Topics: Erectile Dysfunction; Humans; Male; Papaverine; Penile Erection; Penis; Phentolamine; Postoperative | 1988 |