papaverine has been researched along with Pregnancy in 96 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Papaverine exposure was associated with higher rate of preterm delivery (22." | 5.62 | Pregnancy outcomes following gestational exposure to papaverine: An observational comparative study. ( Barchel, D; Berkovitch, M; Berlin, M; Braun, A; Gilan, A; Gueta, I; Kohn, E; Loebstein, R; Markovits, N, 2021) |
| " For both normal pregnancy and pre-eclampsia, the response of pre-constricted arteries to the endothelium-dependent vasodilator, bradykinin, was minimal." | 3.71 | Functional characteristics of chorionic plate placental arteries from normal pregnant women and women with pre-eclampsia. ( Baker, PN; Crocker, IP; Ong, SS; Warren, AY, 2002) |
| "In drotaverine group, there was a mean 15% reduction in the duration of the first stage of labor and a mean 19% reduction in the second stage." | 2.71 | Drotaverine hydrochloride for augmentation of labor. ( Goel, N; Jain, P; Saxena, A; Singh, KC, 2004) |
| "Papaverine exposure was associated with higher rate of preterm delivery (22." | 1.62 | Pregnancy outcomes following gestational exposure to papaverine: An observational comparative study. ( Barchel, D; Berkovitch, M; Berlin, M; Braun, A; Gilan, A; Gueta, I; Kohn, E; Loebstein, R; Markovits, N, 2021) |
| "Adenosine failed to inhibit hypoxanthine uptake." | 1.30 | Hypoxanthine uptake at the fetal side of human placenta proceeds through a nucleobase-preferring carrier and a non-saturable process. ( Acevedo, CG; Bravo, I; Ramírez, M; Rojas, S, 1997) |
| "Thus pregnancy is associated with a reduced intrinsic tone, possibly because of a reduction in an endothelial constrictor influence on the vascular smooth muscle in isolated rat renal interlobar arteries." | 1.30 | Intrinsic tone and passive mechanics of isolated renal arteries from virgin and late-pregnant rats. ( Conrad, KP; Gandley, RE; Griggs, KC; McLaughlin, MK, 1997) |
| "Since terbutaline treatment in premature labor has been shown to increase phosphodiesterase activity in the myometrium, the phosphodiesterase-inhibiting effect of theophylline and papaverine on myometrial preparations from pregnant women has been studied." | 1.27 | In vitro study of phosphodiesterase-inhibiting drugs: a complement to beta-sympathomimetic drug therapy in premature labor? ( Andersson, RG; Berg, G; Rydén, G, 1983) |
| "Prevention of premature labor is of considerable interest in research and clinics." | 1.25 | The treatment of threatened premature labor by tocolytics, Ca++-Antagonists and anti-inflammatory drugs. ( Mosler, KH, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 73 (76.04) | 18.7374 |
| 1990's | 3 (3.13) | 18.2507 |
| 2000's | 11 (11.46) | 29.6817 |
| 2010's | 3 (3.13) | 24.3611 |
| 2020's | 6 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Domokos, D | 1 |
| Fülöp, F | 1 |
| Falkay, G | 1 |
| Gáspár, R | 1 |
| Rzymski, P | 1 |
| Tomczyk, KM | 1 |
| Wilczak, M | 1 |
| Ikeotuonye, AC | 1 |
| Umeora, OJ | 1 |
| Nwafor, JI | 1 |
| Ojumah, BO | 1 |
| Ekwunife, IC | 1 |
| Dimejesi, IB | 1 |
| Luhach, K | 1 |
| Kulkarni, GT | 1 |
| Singh, VP | 1 |
| Sharma, B | 2 |
| Sharma, N | 1 |
| Dhiman, N | 1 |
| Golani, LK | 1 |
| Gueta, I | 1 |
| Braun, A | 1 |
| Gilan, A | 1 |
| Berlin, M | 1 |
| Kohn, E | 1 |
| Barchel, D | 1 |
| Markovits, N | 1 |
| Berkovitch, M | 1 |
| Loebstein, R | 1 |
| Ibis, E | 1 |
| Hayme, S | 1 |
| Baysal, E | 1 |
| Gul, N | 1 |
| Ozkavukcu, S | 1 |
| Ibrahim, MI | 1 |
| Alzeeniny, HA | 1 |
| Ellaithy, MI | 1 |
| Salama, AH | 1 |
| Abdellatif, MA | 1 |
| Madhu, C | 1 |
| Mahavarkar, S | 1 |
| Bhave, S | 1 |
| Tömösközi, Z | 1 |
| Finance, O | 1 |
| Arányi, P | 1 |
| Ong, SS | 1 |
| Crocker, IP | 2 |
| Warren, AY | 2 |
| Baker, PN | 2 |
| HECKSCHER, S | 1 |
| RIEGER, H | 1 |
| TEN BERGE, B | 1 |
| VAN ASSEN, FJ | 1 |
| BAYER, R | 1 |
| CIUCHTA, HP | 1 |
| GAUTIERI, RF | 2 |
| DOMANY, S | 1 |
| CSEFFALVAY, T | 1 |
| MORANMIRANDA, F | 1 |
| GONNELLA, GC | 1 |
| TOKUDA, G | 1 |
| INOUE, S | 1 |
| SOLLA, E | 1 |
| URANGAIMAZ, FA | 2 |
| TONNELIER, E | 1 |
| KLAUER, D | 1 |
| CHEKERDEMIAN, M | 1 |
| MARZETTI, L | 1 |
| BENAGIANO, G | 1 |
| KOCHSIEK, K | 1 |
| SCHELER, F | 1 |
| SANDBERG, F | 1 |
| INGELMAN-SUNDBERG, A | 1 |
| LINDGREN L RYDEN, G | 1 |
| Singh, KC | 1 |
| Jain, P | 1 |
| Goel, N | 1 |
| Saxena, A | 1 |
| McCALL, ML | 2 |
| FINCH, V | 1 |
| TAYLOR, HW | 2 |
| FINCH, TV | 1 |
| TIMONEN, S | 1 |
| SCHRODERUS, KA | 1 |
| Hammer, ES | 1 |
| Cipolla, MJ | 1 |
| Jain, V | 2 |
| Lim, M | 1 |
| Longo, M | 1 |
| Fisk, NM | 1 |
| Gupta, B | 1 |
| Nellore, V | 1 |
| Mittal, S | 1 |
| Roy, A | 1 |
| Patra, KK | 1 |
| Mukhopadhyay, S | 1 |
| Guha, S | 1 |
| Mosler, KH | 5 |
| Zimmer, F | 1 |
| Castell, R | 1 |
| Ewald, P | 1 |
| Büttner, P | 1 |
| Howard, JM | 1 |
| Krantz, KE | 2 |
| Wilde, CJ | 1 |
| Kuhn, NJ | 1 |
| Berg, G | 2 |
| Andersson, RG | 2 |
| Rydén, G | 2 |
| Pańczyk, T | 4 |
| Zrubek, H | 4 |
| Oleszczuk, J | 5 |
| Sawulicka-Oleszczuk, H | 4 |
| Lopucki, M | 1 |
| Wesołowska-Przystupa, A | 1 |
| Chamley, WA | 1 |
| Parkington, HC | 1 |
| O'Shea, KS | 1 |
| Bednarek, W | 1 |
| Weiss, GK | 1 |
| Dail, WG | 1 |
| Ratner, A | 1 |
| Matsumoto, K | 1 |
| Akimoto, A | 1 |
| Shibata, K | 1 |
| Obata, T | 1 |
| Tsuda, T | 1 |
| Tsuboshima, M | 1 |
| Dabek, W | 1 |
| Otani, T | 1 |
| Kai, S | 1 |
| Narushima, M | 1 |
| Ramírez, M | 1 |
| Acevedo, CG | 1 |
| Rojas, S | 1 |
| Bravo, I | 1 |
| Gandley, RE | 1 |
| Griggs, KC | 1 |
| Conrad, KP | 1 |
| McLaughlin, MK | 1 |
| Vedernikov, YP | 1 |
| Syal, AS | 1 |
| Okawa, T | 1 |
| Saade, GR | 1 |
| Garfield, RE | 1 |
| Sokal, D | 1 |
| Hieu, DT | 1 |
| Weiner, DH | 1 |
| Vinh, DQ | 1 |
| Huu Vach, T | 1 |
| Hanenberg, R | 1 |
| Sharma, JB | 1 |
| Pundir, P | 1 |
| Kumar, A | 1 |
| Murthy, NS | 1 |
| Wareing, M | 1 |
| Taggart, MJ | 1 |
| Jameson, D | 1 |
| Buckle, P | 1 |
| Berić, BM | 1 |
| Kupresanin, M | 1 |
| Loizzi, RF | 1 |
| de Pont, JJ | 1 |
| Bonting, SL | 1 |
| Hussa, RO | 1 |
| Story, MT | 1 |
| Pattillo, RA | 1 |
| Kemp, RG | 1 |
| Ferre, F | 1 |
| Breuiller, M | 1 |
| de Pariente, D | 1 |
| Cedard, L | 1 |
| Linka, F | 2 |
| Hruczkowski, L | 1 |
| Hodgson, BJ | 2 |
| Parnham, MJ | 1 |
| Carol, W | 1 |
| Osa, T | 1 |
| Maruta, K | 1 |
| Servin, AL | 1 |
| Jacquot, C | 1 |
| Lussiana, JP | 1 |
| Viel, C | 1 |
| Marshall, JM | 4 |
| Kroeger, EA | 2 |
| Dornhöfer, W | 1 |
| Ehrhart, J | 1 |
| Ward, CO | 1 |
| Marmo, E | 1 |
| Annunziata, A | 1 |
| Urban, J | 1 |
| Czekanowski, R | 1 |
| Lemke, H | 1 |
| Oettel, M | 1 |
| Chemnitius, KH | 1 |
| Osman, OH | 1 |
| Ismail, M | 1 |
| el-Asmar, MF | 1 |
| Ibrahim, SA | 1 |
| Coceani, F | 1 |
| Olley, PM | 1 |
| Hashimoto, H | 1 |
| Unemoto, T | 1 |
| Hayashi, M | 1 |
| Daniel, EE | 1 |
| Ash, JF | 1 |
| Spooner, BS | 1 |
| Wessells, NK | 1 |
| Ifrim, M | 1 |
| Sálájan, V | 1 |
| Kawahara, Y | 1 |
| Yamada, S | 1 |
| Götz, HG | 1 |
| Diamond, J | 2 |
| Ferrero, A | 1 |
| Marzullo, C | 1 |
| Salmoiraghi, ML | 1 |
| Erny, R | 1 |
| Kaern, T | 1 |
| Schäffer, B | 1 |
| Sharley, CB | 1 |
| Dutta, D | 1 |
| Bhargava, KC | 1 |
| Chakravarti, RN | 1 |
| Dhall, SR | 1 |
| Eliason, BC | 1 |
| Posner, HS | 1 |
| Thomsen, K | 1 |
| Schniewind, H | 1 |
| Schultze-Mosgau, H | 1 |
| Krämer, M | 1 |
| Born, H | 1 |
| Amon, K | 1 |
| Amon, I | 1 |
| Chervinskiĭ, AA | 1 |
| Kondranin, GV | 1 |
| Malyshev, IuV | 1 |
| Polianskiĭ, GN | 1 |
| Langanke, D | 1 |
| Keller, J | 1 |
| Chiara, A | 1 |
| Maggioni, G | 1 |
| Hensleigh, PA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of IV PAPAVERINE 80 mg Prior to Catheter Balloon Insertion on Bishop Score and Pain, Double Blinded Randomized Placebo Controlled Trial[NCT05759364] | 128 participants (Anticipated) | Interventional | 2023-05-15 | Recruiting | |||
| Use of Antispasmodic Drotaverine to Shorten the Length of Labor in Nulliparous Women[NCT01639027] | Phase 2/Phase 3 | 352 participants (Actual) | Interventional | 2012-05-31 | Completed | ||
| Liberal Versus Restrictive Platelet Transfusion for Treatment of Hemodynamically Significant Patent Ductus Arteriosus in Thrombocytopenic Preterm Neonates- A Randomized Open Label, Controlled Trial[NCT03022253] | Phase 3 | 44 participants (Anticipated) | Interventional | 2016-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for papaverine and Pregnancy
| Article | Year |
|---|---|
[Clinical pharmacology in obstetrics: regulation of the uterus].
Topics: Adrenergic beta-Agonists; Aspirin; Ergotamine; Female; Humans; Indomethacin; Methylergonovine; Obste | 1975 |
Tocolytic therapy in obstetrics.
Topics: Adrenergic beta-Agonists; Cyclic AMP; Ethanol; Female; Hemorrhage; Humans; Monitoring, Physiologic; | 1974 |
[Obstetric drugs. 16].
Topics: Analgesics; Ergot Alkaloids; Female; Humans; Labor, Induced; Meperidine; Meprobamate; Muscles; Oxyto | 1967 |
7 trials available for papaverine and Pregnancy
| Article | Year |
|---|---|
Drotaverine to shorten the duration of labour in primigravidas: a randomised, double-blind, placebo-controlled trial.
Topics: Double-Blind Method; Female; Humans; Infant, Newborn; Labor Pain; Labor, Obstetric; Oxytocin; Papave | 2022 |
Drotaverine to improve progression of labor among nulliparous women.
Topics: Adult; Double-Blind Method; Female; Humans; Kaplan-Meier Estimate; Labor Pain; Labor Stage, First; P | 2014 |
Drotaverine to improve progression of labor among nulliparous women.
Topics: Adult; Double-Blind Method; Female; Humans; Kaplan-Meier Estimate; Labor Pain; Labor Stage, First; P | 2014 |
Drotaverine to improve progression of labor among nulliparous women.
Topics: Adult; Double-Blind Method; Female; Humans; Kaplan-Meier Estimate; Labor Pain; Labor Stage, First; P | 2014 |
Drotaverine to improve progression of labor among nulliparous women.
Topics: Adult; Double-Blind Method; Female; Humans; Kaplan-Meier Estimate; Labor Pain; Labor Stage, First; P | 2014 |
A randomised controlled study comparing Drotaverine hydrochloride and Valethamate bromide in the augmentation of labour.
Topics: Adult; Cervical Ripening; Cervix Uteri; Female; Humans; Injections, Intramuscular; Labor Stage, Firs | 2010 |
Drotaverine hydrochloride for augmentation of labor.
Topics: Adult; Analgesia, Obstetrical; Analgesics; Cervix Uteri; Double-Blind Method; Female; Humans; Labor | 2004 |
Drotaverine hydrochloride versus hyoscine-N-butylbromide in augmentation of labor.
Topics: Adult; Butylscopolammonium Bromide; Female; Humans; Labor, Obstetric; Papaverine; Parasympatholytics | 2008 |
Study of drotaverine on first stage of labour and pregnancy outcome.
Topics: Drug-Related Side Effects and Adverse Reactions; Female; Humans; Labor Onset; Labor Stage, First; La | 2007 |
Drotaverine hydrochloride vs. valethamate bromide in acceleration of labor.
Topics: Cervix Uteri; Female; Humans; Labor, Obstetric; Papaverine; Parasympatholytics; Pregnancy; Quaternar | 2001 |
86 other studies available for papaverine and Pregnancy
| Article | Year |
|---|---|
Effects of newly synthetized isoquinoline derivatives on rat uterine contractility and ROCK II activity.
Topics: Animals; Dose-Response Relationship, Drug; Female; Isoquinolines; Molecular Structure; Pregnancy; Pr | 2018 |
The Influence of Oral Drotaverine Administration on Materno-Fetal Circulation during the Second and Third Trimester of Pregnancy.
Topics: Administration, Oral; Female; Humans; Infant, Newborn; Papaverine; Pregnancy; Pregnancy Trimester, S | 2022 |
Attenuation of neurobehavioural abnormalities by papaverine in prenatal valproic acid rat model of ASD.
Topics: Animals; Anticonvulsants; Autism Spectrum Disorder; Dose-Response Relationship, Drug; Doublecortin P | 2021 |
Papaverine ameliorates prenatal alcohol-induced experimental attention deficit hyperactivity disorder by regulating neuronal function, inflammation, and oxidative stress.
Topics: Animals; Anxiety; Attention Deficit Disorder with Hyperactivity; Behavior, Animal; Cell Survival; Cy | 2021 |
Pregnancy outcomes following gestational exposure to papaverine: An observational comparative study.
Topics: Cesarean Section; Female; Gestational Age; Humans; Papaverine; Pregnancy; Pregnancy Outcome; Prematu | 2021 |
Efficacy and safety of papaverine as an in vitro motility enhancer on human spermatozoa.
Topics: Acrosome Reaction; Animals; Asthenozoospermia; Cryopreservation; Female; Fertilization in Vitro; Hum | 2021 |
Drotaverine interacts with the L-type Ca(2+) channel in pregnant rat uterine membranes.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Binding, Competitive; Calcium Channel Blockers; Calciu | 2002 |
Functional characteristics of chorionic plate placental arteries from normal pregnant women and women with pre-eclampsia.
Topics: Adult; Analysis of Variance; Arteries; Bradykinin; Chorion; Endothelium, Vascular; Female; Humans; M | 2002 |
Remarks and observation on obstetric analgesia.
Topics: Analgesia, Obstetrical; Female; Humans; Labor, Obstetric; Meperidine; Papaverine; Pregnancy; Work | 1953 |
[Safe mitigation of labor pain by belladonna-exclud suppository].
Topics: Aminopyrine; Analgesia; Anesthesia; Anesthesia and Analgesia; Atropa belladonna; Barbiturates; Femal | 1955 |
[Diabetes mellitus and pregnancy: labor induction with compositrin].
Topics: Cardiovascular Agents; Diabetes Mellitus; Ergot Alkaloids; Female; Humans; Labor, Induced; Labor, Ob | 1957 |
[Testing labor-accelerating substances with an index of effectiveness].
Topics: Anesthesia; Anesthesia, Obstetrical; Atropa belladonna; Female; Humans; Labor, Obstetric; Oxytocics; | 1963 |
EFFECT OF CERTAIN DRUGS ON PERFUSED HUMAN PLACENTAS. II. VASODILATORS.
Topics: Female; Humans; Isoproterenol; Nitroglycerin; Papaverine; Perfusion; Pharmacology; Placenta; Pregnan | 1963 |
[ON THE USE OF CONTINUOUS OXYTOCIN DROP INFUSION IN OBSTETRICS].
Topics: Abortion, Induced; Abortion, Spontaneous; Abortion, Threatened; Female; Glucose; Humans; Obstetrics; | 1963 |
[DIFFERENTIAL DIAGNOSIS OF NON-TRAUMATIC COMAS AND THEIR TREATMENT].
Topics: Addison Disease; Adrenal Insufficiency; Adrenocorticotropic Hormone; Carbon Dioxide; Cerebrovascular | 1963 |
[THE CERVIX UTERI AND DRUGS FROM THE OBSTETRICAL VIEWPOINT].
Topics: Cardiovascular Agents; Cervix Uteri; Dihydroergotoxine; Ergot Alkaloids; Estriol; Female; Humans; Hy | 1964 |
[OUR PRINCIPLES OF THERAPY IN MEDICATION IN LABOR (FURTHER OBSERVATIONS ON SERPASIL)].
Topics: Ergonovine; Female; Humans; Labor, Obstetric; Papaverine; Pharmacology; Pregnancy; Quinine; Reserpin | 1964 |
[THERAPEUTICS OF ARTERIAL HYPERTENSION IN PREGNANCY].
Topics: Female; Guanethidine; Hibernation; Humans; Hydralazine; Hypertension; Hypothermia, Induced; Maternal | 1964 |
[CLINICAL EVALUATION OF THE USE OF A DRUG WITH FIBRINOLYTIC ACTION IN THE THERAPY OF GESTOSIS IN THE THIRD TRIMESTER].
Topics: Antihypertensive Agents; Diuretics; Drug Therapy; Female; Humans; Niacin; Nicotinic Acids; Papaverin | 1964 |
[Comparative experimental studies on drugs with peripheral vascular effects with special reference to a placental extract].
Topics: Acetylcholine; Female; Papaverine; Placenta; Placental Extracts; Pregnancy | 1962 |
In vitro studies of the motility of the human uterus. VI. The effects of papaverine, atropine, pethidine, relaxin and spasmaverin on the spontaneous motility on different parts of the pregnant and non-pregnant uterus.
Topics: Atropine; Female; Humans; In Vitro Techniques; Meperidine; Muscle Relaxants, Central; Musculoskeleta | 1961 |
The cerebral effects of papaverine hydrochloride in toxemia of pregnancy.
Topics: Brain; Female; Humans; Papaverine; Pre-Eclampsia; Pregnancy; Sepsis; Toxemia | 1951 |
The cerebral effects of papaverine hydrochloride in toxemia of pregnancy.
Topics: Cerebral Arteries; Cerebral Veins; Female; Humans; Papaverine; Pre-Eclampsia; Pregnancy; Veins | 1951 |
The effect of papaverin on the circulation of pre-eclamptic and eclamptic patients.
Topics: Eclampsia; Female; Humans; Papaverine; Pre-Eclampsia; Pregnancy | 1950 |
Arterial wall hyperplasia is increased in placental compared with myoendometrial radial uterine arteries from late-pregnant rats.
Topics: Animals; Arteries; Case-Control Studies; Female; Hyperplasia; Muscle, Smooth, Vascular; Myometrium; | 2005 |
Inhibitory effect of erythropoietin on contractility of human chorionic plate vessels.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Arteries; Chorion; Enzyme | 2006 |
Tocolysis.
Topics: Animals; Chlordiazepoxide; Diazepam; Female; Guinea Pigs; Humans; In Vitro Techniques; Muscle Contra | 1966 |
[Significance of the enlargement of the pregnant rat uterus in wall tension, elasticity and function of the myometrium].
Topics: Animals; Elasticity; Female; Muscle Contraction; Papaverine; Pregnancy; Pregnancy, Animal; Rats; Ute | 1966 |
Transfer and use of glucose in the human placenta during in vitro perfusion and the associated effects of oxytocin and papaverine.
Topics: Biological Transport; Blood Glucose; Dialysis; Erythrocytes; Female; Glucose; Humans; In Vitro Techn | 1967 |
Lactose synthesis and the utilisation of glucose by rat mammary acini.
Topics: Animals; Bucladesine; Cyclic AMP; Female; Glucose; Intracellular Fluid; Lactation; Lactose; Mammary | 1981 |
In vitro study of phosphodiesterase-inhibiting drugs: a complement to beta-sympathomimetic drug therapy in premature labor?
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adult; Drug Interactions; Female; Humans; Muscle Relaxation; My | 1983 |
[Metabolism of triglycerides of the placenta during extraorganic circulation].
Topics: Energy Metabolism; Female; Humans; Maternal-Fetal Exchange; Metaproterenol; Papaverine; Perfusion; P | 1984 |
Relaxin inhibits the plateau component of the action potential in the circular myometrium of the rat.
Topics: Action Potentials; Animals; Calcium; Dinoprost; Female; In Vitro Techniques; Isoproterenol; Membrane | 1984 |
Calcium and neural tube closure defects: an in vitro study.
Topics: Animals; Calcimycin; Calcium; Central Nervous System; Female; Mice; Neural Tube Defects; Papaverine; | 1982 |
[Energetic metabolism of the placenta and vascular blood flow as criteria for the choice of drugs in risk pregnancy--results of our investigations].
Topics: Female; Humans; Metaproterenol; Papaverine; Placenta; Pregnancy; Pressure; Risk; Vascular Resistance | 1983 |
Evidence for direct neural control of ovarian steroidogenesis in rats.
Topics: Animals; Diestrus; Electric Stimulation; Female; Ovary; Papaverine; Phentolamine; Pregnancy; Progest | 1982 |
[Effects of 16,16-dimethyl-trans-delta 2-PGE1 methyl ester (ONO-802) on uterine motility (author's transl)].
Topics: Alprostadil; Animals; Cricetinae; Dose-Response Relationship, Drug; Female; Papaverine; Pregnancy; P | 1981 |
[Metabolic capacity of human placenta with regard to carbohydrate metabolism under the effect of orciprenaline and papaverine under experimental conditions].
Topics: Female; Humans; In Vitro Techniques; Lactates; Metaproterenol; Oxidation-Reduction; Papaverine; Perf | 1980 |
[Effect of orciprenaline and papaverine on glucose ultilization in the placenta, perfused in vitro].
Topics: Dose-Response Relationship, Drug; Female; Glucose; Humans; In Vitro Techniques; Metaproterenol; Papa | 1980 |
Ejaculation obtained by intracavernous papaverine in a cervical spinal cord injury patient resulting in pregnancy and childbirth. Case report.
Topics: Adult; Ejaculation; Electric Stimulation; Female; Humans; Injections; Male; Papaverine; Penis; Pregn | 1994 |
Hypoxanthine uptake at the fetal side of human placenta proceeds through a nucleobase-preferring carrier and a non-saturable process.
Topics: Adenine; Adenosine; Biological Transport; Blood Flow Velocity; Female; Fetus; Guanine; Humans; Hypox | 1997 |
Intrinsic tone and passive mechanics of isolated renal arteries from virgin and late-pregnant rats.
Topics: Animals; Endothelium, Vascular; Female; In Vitro Techniques; Muscle Tonus; Muscle, Smooth, Vascular; | 1997 |
The role of cyclic nucleotides in the spontaneous contractility and responsiveness to nitric oxide of the rat uterus at midgestation and term.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Colforsin; Cyclic AMP; Cyclic GMP; Female; Guanylate Cyclase; | 2000 |
Long-term follow-up after quinacrine sterilization in Vietnam. Part I: interim efficacy analysis.
Topics: Administration, Intravaginal; Administration, Oral; Adult; Cohort Studies; Delayed-Action Preparatio | 2000 |
Characterization of small arteries isolated from the human placental chorionic plate.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Arteries; Chorionic Villi | 2002 |
A comparison of anti-inflammatory and other compounds on the spontaneously contracting pregnant rat uterus.
Topics: Animals; Anti-Inflammatory Agents; Chlorpromazine; Desipramine; Diazepam; Female; In Vitro Technique | 1977 |
[Legal abortion during the first trimester of pregnancy at the University Hospital for Women in Novi Sad (1960-1975)].
Topics: Abortion, Therapeutic; Atropine; Female; Hospitals, University; Humans; Muscle Relaxation; Papaverin | 1977 |
Inhibition by cyclic AMP of lactose production in lactating guinea pig mammary gland slices.
Topics: Animals; Bucladesine; Colchicine; Cyclic AMP; Cytochalasin B; Dose-Response Relationship, Drug; Epin | 1975 |
Effect of cyclic 3':5'-AMP derivatives prostaglandins and related agents on human chorionic gonadotropin secretion in human malignant trophoblast in culture.
Topics: Adenine; Adenylyl Cyclases; Bucladesine; Cell Line; Chorionic Gonadotropin; Cyclic AMP; Female; Fluo | 1977 |
[3'5'-Cyclic AMP phosphodiesterase activity in the internal and external layers of human myometrium at the end of pregnancy].
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Caffeine; Female; Humans; Imidazoles; Indomethacin; Kinetics; M | 1977 |
The treatment of threatened premature labor by tocolytics, Ca++-Antagonists and anti-inflammatory drugs.
Topics: Adrenergic beta-Agonists; Animals; Anti-Inflammatory Agents; Aspirin; Calcium; Drug Therapy, Combina | 1975 |
[Effect of orciprenaline and papaverine on the pressure during the perfusion of the human placenta in experimental conditions].
Topics: Female; Humans; Metaproterenol; Papaverine; Placenta; Pregnancy; Pressure | 1978 |
Effect of isoproterenol on uptake of calcium-45 by pregnant human and rat myometrium.
Topics: Animals; Calcium; Calcium Radioisotopes; Female; Humans; In Vitro Techniques; Isoproterenol; Lithium | 1976 |
The effect of metyrapone on uterine prostaglandin output and smooth muscle activity.
Topics: Animals; Female; Ileum; In Vitro Techniques; Isoproterenol; Metyrapone; Muscle, Smooth; Papaverine; | 1976 |
[Obstetrical emergencies, concerning the mother].
Topics: Acute Kidney Injury; Blood Coagulation Disorders; Calcium; Embolism, Amniotic Fluid; Emergencies; Fe | 1975 |
The mechanical response of rat myometrium to adenosine triphosphate in Ca-free solution.
Topics: Adenosine Triphosphate; Animals; Calcium; Cyclic AMP; Female; In Vitro Techniques; Papaverine; Potas | 1987 |
Effects of different phosphodiesterase-inhibiting drugs on human pregnant myometrium: an in vitro study.
Topics: Female; Humans; In Vitro Techniques; Muscle Relaxation; Myometrium; Papaverine; Phosphodiesterase In | 1987 |
Metabolism of 6,7-dimethoxy 4-(p-chlorobenzyl)-isoquinoline. I. Single-dose pharmacokinetics in the rat and mouse.
Topics: Animals; Autoradiography; Biotransformation; Blood Vessels; Female; Kinetics; Liver; Male; Mice; Pap | 1985 |
Adrenergic influences on uterine smooth muscle.
Topics: Animals; Butyrates; Calcium; Chlorides; Cyclic AMP; Female; In Vitro Techniques; Isoproterenol; Lant | 1973 |
Beta-adrenergic effects on rat myometrium: mechanisms of membrane hyperpolarization.
Topics: Adrenergic beta-Agonists; Aminophylline; Animals; Calcium; Cell Membrane; Cell Membrane Permeability | 1973 |
Effect of certain drugs on perfused human placenta. 8. Angiotensin-II antagonists.
Topics: Acetates; Angiotensin II; Atropine; Blood Pressure Determination; Cobalt; Cocaine; Cyproheptadine; D | 1968 |
[Pharmacodynamic properties of 1-(2'-piperidine-ethyl)-4,4-bis-(para-methoxy-phenyl)-2,5-imidazolidinedione-chlorhydrate (I. 255). Studies of the effect on musculature of intestine gallbladder, uterus, bladder and trachea in vitro].
Topics: Acetylcholine; Animals; Atropine; Barium; Cats; Chlorides; Colon; Depression, Chemical; Duodenum; Fe | 1970 |
Effect of blockade of adrenergic alpha-receptors on the activity of preparations stimulating and inhibiting the contraction of the rat uterus.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Animals; Epinephrine; Female; Norepinephrine; Oxytocics | 1970 |
[Pharmacologic-endocrinological findings in animal experiments with TURISYNCHRON and SUISYNCHROM. 2. Toxicologic findings].
Topics: Acute Disease; Administration, Oral; Animals; Atropine; Body Weight; Chlorpromazine; Chronic Disease | 1974 |
Effect on the rat uterus of the venom from the scorpion Leiurus quinquestriatus.
Topics: Animals; Atropine; Chlorpheniramine; Cocaine; Diphenhydramine; Estrus; Female; Hexamethonium Compoun | 1972 |
The response of the ductus arteriosus to prostaglandins.
Topics: Anaerobiosis; Animals; Dose-Response Relationship, Drug; Ductus Arteriosus; Female; In Vitro Techniq | 1973 |
Inhibitory action of spermine on the contractions of rat uterus.
Topics: Animals; Calcium; Electrophysiology; Female; Muscle Contraction; Muscle, Smooth; Papaverine; Pregnan | 1973 |
Studies concerning the source of calcium for contraction of rat myometrium.
Topics: Acetylcholine; Action Potentials; Animals; Calcium; Calcium Radioisotopes; Carbon Radioisotopes; Chl | 1973 |
Effects of papaverine and calcium-free medium on salivary gland morphogenesis.
Topics: Animals; Calcium; Culture Media; Epithelial Cells; Epithelium; Female; In Vitro Techniques; Mice; Mi | 1973 |
[Correlation between pregnancy complications and congenital malformations in the newborn infant].
Topics: Abnormalities, Drug-Induced; Carbohydrate Metabolism; Congenital Abnormalities; Drug-Related Side Ef | 1973 |
[Pharmacological studies on the vascular system of the human placenta].
Topics: Acetylcholine; Atropine; Blood Vessels; Caffeine; Carbon Dioxide; Ephedrine; Epinephrine; Ergotamine | 1974 |
Smooth muscle relaxants: dissociation between resting membrane potential and resting tension in rat myometrium.
Topics: Animals; Catecholamines; Epinephrine; Female; In Vitro Techniques; Isoproterenol; Membrane Potential | 1969 |
A comparison of the effects of various smooth muscle relaxants on the electrical and mechanical activity of rat uterus.
Topics: Action Potentials; Animals; Calcium; Cell Membrane; Electricity; Epinephrine; Female; In Vitro Techn | 1969 |
[Intensive therapy of gestoses. Our experience in the years 1969-1971].
Topics: Betamethasone; Brain Edema; Diazepam; Ergoloid Mesylates; Female; Furosemide; Humans; Mannitol; Papa | 1971 |
[Effects of uterine contraction on the fetus].
Topics: Anesthesia, Obstetrical; Female; Fetal Diseases; Fetal Heart; Fetus; Humans; Labor, Obstetric; Metap | 1972 |
Effectiveness of induction of labor by intraveneous oxytocin.
Topics: Birth Weight; Cesarean Section; Delivery, Obstetric; Female; Gestational Age; Humans; Infant, Newbor | 1971 |
The value of physiotherapy in obstetrics.
Topics: Acetaminophen; Anesthesia, Obstetrical; Anesthetics, Local; Aspirin; Codeine; Conditioning, Psycholo | 1970 |
Therapeutic studies in experimental amniotic fluid embolism in rabbits.
Topics: Anaphylaxis; Animals; Atropine; Bronchial Spasm; Disease Models, Animal; Electrocardiography; Emboli | 1970 |
Reduced passage of carbon-14-dieldrin to the fetal rat by phenobarbital but not by eight other drugs or dieldrin.
Topics: Administration, Oral; Ammonium Chloride; Animals; Aspirin; Bicarbonates; Brain; Brain Chemistry; Car | 1971 |
[Effect and passage of vasoactive drugs in the in vitro perfused placenta of guinea pigs].
Topics: Amides; Animals; Dextrans; Epinephrine; Female; Glucose; Guinea Pigs; Indoles; Lysergic Acid Diethyl | 1967 |
[Experimental studies of a new spasmoanalgetic on the rat uterus and 1st clinical experience in obstetrics].
Topics: Acetates; Adult; Animals; Female; Humans; In Vitro Techniques; Injections, Intravenous; Labor, Obste | 1968 |
[Use of mannitol and vasodilators for preventing and treating acute renal insufficiency].
Topics: Abortion, Septic; Acute Kidney Injury; Aminophylline; Female; Humans; Mannitol; Papaverine; Poisonin | 1968 |
[Problems of labor pain inhibition by pharmacological agents].
Topics: Bronchodilator Agents; Chlordiazepoxide; Diazepam; Female; Halothane; Humans; Infant Mortality; Isop | 1969 |
[Effect of papaquine on the course of labor and puerperium in comparison with dolcontral and spasmonal].
Topics: Analgesics; Brain Injuries; Dystocia; Female; Humans; Infant Mortality; Infant, Newborn; Obstetric L | 1965 |
[On medico-surgical induction of labor. Clinical study of 310 cases].
Topics: Adult; Castor Oil; Ergonovine; Female; Humans; Labor, Induced; Papaverine; Pregnancy; Quinine | 1965 |
Extracorporeal perfusion of the human placenta. I. Placental transfer of ascorbic acid.
Topics: Ascorbic Acid; Female; Humans; In Vitro Techniques; Oxytocin; Papaverine; Perfusion; Placenta; Pregn | 1966 |